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"Hypoplastic left heart"

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https://www.readbyqxmd.com/read/29900667/the-risk-of-overzealous-application-of-hybrid-strategies-for-patients-with-biventricular-cardiac-anomalies-invited-commentary-regarding-hybrid-strategies-for-high-risk-non-hypoplastic-left-heart-syndrome-patients
#1
https://www.readbyqxmd.com/read/29896780/hybrid-strategies-for-high-risk-non-hypoplastic-left-heart-syndrome-patients
#2
Syed M Rehman, Antonio Ravaglioli, Kanchana Singappuli, Kevin Roman, James Gnanapragasam, Duminda Samarasinghe, Nicola Viola
Single-stage repair of complex cardiac abnormalities in high-risk neonates presents formidable challenges. The majority of hybrid strategies involving bilateral pulmonary artery banding (bPAB) with or without patent ductus arteriosus (PDA) stenting is described in the setting of hypoplastic left heart syndrome. We present a series of cases describing two-stage repair with initial palliative hybrid procedures involving bPAB with or without PDA stenting. This allows weight gain and stabilization of circulation before complete repair, provides good results, and may overcome risk factors associated with single-stage repair in neonates...
June 12, 2018: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29890146/anomalous-origin-of-left-coronary-artery-from-aortic-arch-associated-with-hlhs
#3
Satoshi Asada, Masaaki Yamagishi, Koichi Nishida, Shintaro Okazaki, Yoshinobu Nakayama, Osamu Monta, Yasushi Tsutsumi, Hirokazu Ohashi
Anomalous origin of the coronary artery from the aortic arch associated with hypoplastic left heart syndrome is an extremely rare anomaly. Coronary anomalies can significantly deteriorate the clinical outcomes of hypoplastic left heart syndrome. We describe the case of a newborn with concomitant hypoplastic left heart syndrome and abnormal origin of the left coronary artery arising from the distal aortic arch.
June 8, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29886615/-postoperative-management-of-hypoplastic-left-heart-syndrome-after-norwood-stage%C3%A2-operation
#4
Z J Zheng, X J Wu, S S Shi
No abstract text is available yet for this article.
June 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29859676/preoperative-cerebral-hemodynamics-from-birth-to-surgery-in-neonates-with-critical-congenital-heart-disease
#5
Jennifer M Lynch, Tiffany Ko, David R Busch, John J Newland, Madeline E Winters, Kobina Mensah-Brown, Timothy W Boorady, Rui Xiao, Susan C Nicolson, Lisa M Montenegro, J William Gaynor, Thomas L Spray, Arjun G Yodh, Maryam Y Naim, Daniel J Licht
BACKGROUND: Hypoxic-ischemic white matter brain injury commonly occurs in neonates with critical congenital heart disease. Recent work has shown that longer time to surgery is associated with increased risk for this injury. In this study we investigated changes in perinatal cerebral hemodynamics during the transition from fetal to neonatal circulation to ascertain mechanisms that might underlie this risk. METHODS: Neonates with either transposition of the great arteries (TGA) or hypoplastic left heart syndrome (HLHS) were recruited for preoperative noninvasive optical monitoring of cerebral oxygen saturation, cerebral oxygen extraction fraction, and cerebral blood flow using diffuse optical spectroscopy and diffuse correlation spectroscopy, 2 noninvasive optical techniques...
May 3, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29846596/utility-of-a-super-flexible-three-dimensional-printed-heart-model-in-congenital-heart-surgery
#6
Takaya Hoashi, Hajime Ichikawa, Tomohiro Nakata, Masatoshi Shimada, Hideto Ozawa, Akihiko Higashida, Kenichi Kurosaki, Suzu Kanzaki, Isao Shiraishi
OBJECTIVES: The objective of this study was to assess the utility of 3D printed heart models of congenital heart disease for preoperative surgical simulation. METHODS: Twenty patient-specific 3D models were created between March 2015 and August 2017. All operations were performed by a young consultant surgeon who had no prior experience with complex biventricular repair. All 15 patients with balanced ventricles had outflow tract malformations (double-outlet right ventricle in 7 patients, congenitally corrected transposition of great arteries in 5, transposition of great arteries in 1, interrupted aortic arch Type B in 1, tetralogy of Fallot with pulmonary atresia and major aortopulmonary collateral arteries in 1)...
May 28, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29845825/managing-fertile-women-under-lithium-treatment-the-challenge-of-a-teratology-information-service
#7
Caterina Neri, Carmen De Luca, Luisa D'oria, Angelo Licameli, Marta Nucci, Marcella Pellegrino, Alessandro Caruso, Marco De Santis
BACKGROUND: The objective of the present study is to review the literature regarding the management of fertile patients under lithium treatment for bipolar disorder and to report the experience of our Teratology Information Service over the past thirteen years in managing women treated with lithium during preconception, pregnancy and breastfeeding. METHODS: This research focuses on a selective review of the literature and a retrospective survey has been carried out on fertile women under lithium treatment who called our service at A...
June 2018: Minerva Ginecologica
https://www.readbyqxmd.com/read/29803061/cerebral-abscess-in-a-young-adult-with-hypoplastic-left-heart-syndrome
#8
Garret P Greeneway, James L West, Daniel E Couture, Wesley Hsu
BACKGROUND: Cerebral abscesses are rare, potentially life-threatening entities that result from local spread or hematogenous dissemination to the brain. Prompt diagnosis and initiation of treatment is key in lowering morbidity and preventing mortality associated with cerebral abscesses. Congenital heart diseases with right-to-left intracardiac shunts can be complicated by brain abscesses via paradoxical embolism of infected microthrombi. Hypoplastic left heart syndrome (HLHS) is a rare congenital heart disease characterized by an underdeveloped left heart that utilizes intracardiac shunting to achieve adequate systemic circulation...
May 23, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29794380/successful-treatment-of-protein-losing-enteropathy-and-plastic-bronchitis-by-biphasic-cuirass-ventilation-in-a-patient-with-failing-fontan-circulation
#9
Seigo Okada, Jun Muneuchi, Yusaku Nagatomo, Kaori Nonaka, Chiaki Iida, Hiromitsu Shirouzu, Ryohei Matsuoka, Mamie Watanabe, Kunitaka Joo
We present a 16-year-old male patient with hypoplastic left heart syndrome who developed protein-losing enteropathy (PLE) and plastic bronchitis (PB) after a Fontan operation. He received medical therapies, including albumin infusion, unfractionated heparin, and high-dose anti-aldosterone therapy but could not obtain clinical relief. Biphasic cuirass ventilation (BCV) led to expectoration of bronchial casts and prompt resolution of PB. Notably, clinical symptoms related to PLE were dramatically improved after starting BCV...
May 23, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29788322/outcomes-and-risk-factors-associated-with-tricuspid-valve-repair-in-children-with-hypoplastic-left-heart-syndrome
#10
Bahaaldin Alsoufi, Raina Sinha, Courtney McCracken, Janet Figueroa, Firat Altin, Kirk Kanter
OBJECTIVES: Tricuspid valve (TV) competence is important for successful palliation of hypoplastic left heart syndrome (HLHS). We report our experience with TV repair in HLHS patients with a focus on TV and right ventricular (RV) function and associated clinical outcomes. METHODS: From 2002 to 2012, 219 neonates with HLHS underwent the Norwood operation. Thirty patients who underwent TV repair at various stages comprised our current series cohort. Echocardiographic and clinical data were reviewed to determine the effectiveness of TV repair and outcomes of the patients...
May 19, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29787689/patient-specific-multiscale-computational-fluid-dynamics-assessment-of-embolization-rates-in-the-hybrid-norwood-effects-of-size-and-placement-of-the-reverse-blalock-taussig-shunt
#11
Ray Otto Prather, John Seligson, Marcus Ni, Eduardo Divo, Alain Kassab, William DeCampli
The hybrid Norwood operation is performed to treat hypoplastic left heart syndrome. Distal arch obstruction may compromise flow to the brain. In a variant of this procedure, a synthetic graft (RBTS) is placed between the pulmonary trunk and innominate artery to improve upper torso blood flow. Thrombi originating in the graft may embolize to the brain. In this study we used computational fluid dynamics (CFD) and particle tracking to investigate the patterns of particle embolization as a function of the anatomic position of the RBTS...
May 22, 2018: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29784679/surgical-palliation-for-hypoplastic-left-heart-syndrome-for-now-just-keep-doing-what-you-do-best
#12
EDITORIAL
Charles D Fraser
No abstract text is available yet for this article.
May 22, 2018: Circulation
https://www.readbyqxmd.com/read/29777898/a-survey-of-health-professionals-views-on-acceptable-gestational-age-and-termination-of-pregnancy-for-fetal-anomaly
#13
Lisa Crowe, Ruth H Graham, Stephen C Robson, Judith Rankin
Termination of pregnancy for fetal anomaly is legal in the UK with no upper limit, if two doctors, in good faith, agree "there is a substantial risk that if the child were born it would suffer from such physical or mental abnormalities as to be seriously handicapped". This is Clause E of the Human Fertlisation and Embryology Act. The most commonly sighted Clause is C, which states "the pregnancy has not exceeded its twenty-fourth week and that the continuance of the pregnancy would involve risk, greater than if the pregnancy were terminated, of injury to the physical or mental health of the pregnant woman"...
May 16, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29777281/right-ventricular-systolic-function-parameters-in-hypoplastic-left-heart-syndrome
#14
S Javed Zaidi, Jamie Penk, Vivian W Cui, Supaluck Kanjanauthai, David A Roberson
Assessment of the systolic function of the right ventricle (RV) in patients with hypoplastic left heart syndrome (HLHS) is important. The asymmetric shape and heavy trabeculations make accurate assessment of RV systolic function challenging. Novel measures of RV function could be helpful in distinguishing reduced versus preserved function in HLHS and may also be worse in HLHS with preserved function compared to normal controls. These novel methods offer promise, but research and clinical applicability is hindered as no cut-off values for normal function have been established...
May 18, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29774394/longitudinal-health-care-cost-in-hypoplastic-left-heart-syndrome-palliation
#15
Jesse E Hansen, Nicolas L Madsen, Laurie Bishop, David L S Morales, Jeffrey B Anderson
Management of hypoplastic left heart syndrome (HLHS) is resource intensive. Heath care systems are pressured to provide value to patients by improving outcomes while decreasing costs. A single-center retrospective cohort of infants with HLHS who underwent Norwood procedure or hybrid Norwood from 2004 to 2014 and survived to first outpatient follow up were studied. The primary outcome was total cost through 12 months with a sub-analysis of patients with 60 months of data. Costs were calculated using internal cost accounting system and reported by cost center...
May 17, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29770299/regenerative-medicine-therapy-for-single-ventricle-congenital-heart-disease
#16
REVIEW
Chetan Ambastha, Gregory J Bittle, David Morales, Nathaniel Parchment, Progyaparamita Saha, Rachana Mishra, Sudhish Sharma, Alexander Vasilenko, Muthukumar Gunasekaran, Manal T Al-Suqi, Deqiang Li, Peixin Yang, Sunjay Kaushal
One of the most complex forms of congenital heart disease (CHD) involving single ventricle physiology is hypoplastic left heart syndrome (HLHS), characterized by underdevelopment of the left ventricle (LV), mitral and aortic valves, and narrowing of the ascending aorta. The underdeveloped LV is incapable of providing long-term systemic flow, and if left untreated, the condition is fatal. Current treatment for this condition consists of three consecutive staged palliative operations: the first is conducted within the first few weeks of birth, the second between 4 to 6 months, and the third and final surgery within the first 4 years...
April 2018: Translational Pediatrics
https://www.readbyqxmd.com/read/29756326/gastrostomy-tube-placement-among-infants-with-hypoplastic-left-heart-syndrome-undergoing-stage-1-palliation
#17
Parthak Prodhan, Xinyu Tang, Jeffrey Gossett, Brandon Beam, Janet Simsic, Nancy Ghanayem, Nahed O ElHassan
OBJECTIVE: Different feeding strategies have been suggested to improve growth and survival of infants with hypoplastic left heart syndrome following stage 1 palliation. The study objective was to assess hospital mortality following stage 1 palliation among infants with hypoplastic left heart syndrome who had two feeding modalities, gastrostomy tube vs no gastrostomy tube. DESIGN: Retrospective study design. SETTING: Multicenter pediatric heath information system database...
May 13, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/29754919/balloon-expandable-stents-for-recoarctation-of-the-aorta-in-small-children-two-centre-experience
#18
K Gendera, P Ewert, D Tanase, S Georgiev, T Genz, P Bambul Heck, T Moszura, I Malcic, J Cleuziou, A Eicken
BACKGROUND: In young patients with native aortic coarctation (CoA), the management of choice is surgery. However, in re-coarctation (re-CoA) surgery is associated with increased morbidity and even mortality. Some children with native CoA present relative contraindications for surgery. METHODS: From 2006 to 2017, thirty-four patients (male n = 20; 59%) from two centres with re-CoA (31) and native CoA (3) were managed by stent implantation with premounted balloon expandable stents...
July 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29754202/regional-differences-in-cost-and-length-of-stay-in-neonates-with-hypoplastic-left-heart-syndrome
#19
Luma Essaid, Paula D Strassle, Eric G Jernigan, Jennifer S Nelson
Hypoplastic left heart syndrome (HLHS) is a highly resource-intensive diagnosis. Geographic variation in cost and length of stay (LOS) in HLHS is not well described. Neonates diagnosed with HLHS between 2000 and 2012 were identified using the Kids' Inpatient Database. Hospitalizations were stratified into two groups: (1) birth and (2) secondary. United States regional differences in hospital charges and LOS were compared using adjusted linear regression. Of 2431 birth hospitalizations, 449 neonates (18.5%) died while inpatient and mortality rates differed by region (p = 0...
May 12, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29748699/longitudinal-deformation-of-the-right-ventricle-in-hypoplastic-left-heart-syndrome-a-comparative-study-of-2d-feature-tracking-magnetic-resonance-imaging-and-2d-speckle-tracking-echocardiography
#20
Mona Salehi Ravesh, Carsten Rickers, Finn Jonathan Bannert, David Hautemann, Abdullah Al Bulushi, Dominik Daniel Gabbert, Philip Wegner, Eva Kis, Jan Hinnerk Hansen, Michaeal Jerosch-Herold, H-H Kramer, Jana Logoteta
In hypoplastic left heart syndrome (HLHS), long-term outcome is closely related to right ventricular function. Echocardiography and magnetic resonance imaging (MRI) are routinely used for functional assessment. MRI 2D-tissue feature tracking (2D-FT) allows quantification of myocardial deformation but has not yet been applied to HLHS patients. We sought to investigate the feasibility of this technique and to compare the results to 2D-speckle tracking echocardiography (2D-STE). In routine MRI 2D anatomical four chamber view, cine images were recorded in 55 HLHS patients (median age 4...
May 10, 2018: Pediatric Cardiology
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