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https://www.readbyqxmd.com/read/28239913/-sky-full-of-stars-pattern-dermoscopic-findings-in-a-desmoplastic-giant-congenital-melanocytic-nevus
#1
Pablo Martín-Carrasco, José Bernabeu-Wittel, Javier Dominguez-Cruz, Teresa Zulueta Dorado, Julian Conejo-Mir Sanchez
Desmoplastic giant congenital melanocytic nevus (DGCN) is an uncommon variant of congenital nevus, presenting as a progressive induration and hypopigmentation of the lesion that occasionally causes hair loss and even total or partial disappearance of the nevus. A 6-month-old girl with a giant congenital melanocytic nevus that involved the entire posterior side of the right thigh was seen in our department. Nine months later, the peripheral area of the nevus presented as a marked induration with hypopigmentation...
February 27, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28229821/integration-of-capillary-microscopy-and-dermoscopy-into-the-rheumatology-fellow-curriculum
#2
Christopher Hatzis, Daniele Lerner, Stephen Paget, Maurizio Cutolo, Vanessa Smith, Robert Spiera, Jessica Gordon
OBJECTIVES: This study evaluates a novel, three-part nailfold capillaroscopy training curriculum for adult and paediatric rheumatology fellows. METHODS: All rheumatology fellows training at an academic medical centre took part in the three-part nailfold capillaroscopy curriculum. Tests of fellows' usage, interest, confidence, and ability in nailfold capillaroscopy were taken at multiple time-points throughout the curriculum. RESULTS: Fellows self-reported high levels of interest, increased confidence in delineating normal and abnormal nailfold capillaries (p=0...
February 10, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28226758/a-deep-bag-of-features-model-for-the-classification-of-melanomas-in-dermoscopy-images
#3
S Sabbaghi, M Aldeen, R Garnavi, S Sabbaghi, M Aldeen, R Garnavi, M Aldeen, S Sabbaghi, R Garnavi
Deep learning and unsupervised feature learning have received great attention in past years for their ability to transform input data into high level representations using machine learning techniques. Such interest has been growing steadily in the field of medical image diagnosis, particularly in melanoma classification. In this paper, a novel application of deep learning (stacked sparse auto-encoders) is presented for skin lesion classification task. The stacked sparse auto-encoder discovers latent information features in input images (pixel intensities)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226756/multi-scale-classification-based-lesion-segmentation-for-dermoscopic-images
#4
Mani Abedini, Noel Codella, Rajib Chakravorty, Rahil Garnavi, David Gutman, Brian Helba, John R Smith, Mani Abedini, Noel Codella, Rajib Chakravorty, Rahil Garnavi, David Gutman, Brian Helba, John R Smith, John R Smith, Rahil Garnavi, David Gutman, Mani Abedini, Brian Helba, Rajib Chakravorty, Noel Codella
This paper presents a robust segmentation method based on multi-scale classification to identify the lesion boundary in dermoscopic images. Our proposed method leverages a collection of classifiers which are trained at various resolutions to categorize each pixel as "lesion" or "surrounding skin". In detection phase, trained classifiers are applied on new images. The classifier outputs are fused at pixel level to build probability maps which represent lesion saliency maps. In the next step, Otsu thresholding is applied to convert the saliency maps to binary masks, which determine the border of the lesions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28223744/usefulness-of-dermoscopy-in-the-differential-diagnosis-of-ruptured-and-unruptured-epidermal-cysts
#5
Kee Suck Suh, Dong Young Kang, Jong Bin Park, Myeong Hyeon Yang, Joon Hee Kim, Kang Hoon Lee, Sang Hwa Han, Yun Deok Choi, Sang Tae Kim, Min Soo Jang
BACKGROUND: An epidermal cyst is a common keratin-filled epithelial-lined cyst. The treatment of choice for epidermal cysts is surgical excision. If the cyst becomes ruptured, incision and drainage with oral antibiotic therapy or intralesional steroid injection are required. OBJECTIVE: To analyze the dermoscopic features that can differentiate between ruptured and unruptured epidermal cysts. METHODS: The clinical and dermoscopic features of the pathologically confirmed epidermal cysts of two subgroups of 38 patients, 20 with unruptured cysts and 18 with ruptured cysts, were reviewed...
February 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28218469/diagnostic-accuracy-of-reflectance-confocal-microscopy-using-vivascope-for-detecting-and-monitoring-skin-lesions-a-systematic-review
#6
S J Edwards, G Osei-Assibey, R Patalay, V Wakefield, C Karner
BACKGROUND: Skin cancer is one of the most common cancers in the UK. Patients with suspicious skin lesions are assessed clinically with/without dermoscopy, and lesions still considered suspicious are then surgically removed or have the diagnosis confirmed by a punch biopsy. AIM: To evaluate the diagnostic accuracy of the in vivo VivaScope(©) reflective confocal microscopy (RCM) system, a noninvasive technology designed to provide a more accurate presurgical diagnosis, leading to fewer biopsies of benign lesions, or to provide greater accuracy for lesion margins...
February 20, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28218344/familial-melanoma-associated-with-li-fraumeni-syndrome-and-atypical-mole-syndrome-total-body-digital-photography-dermoscopy-and-confocal-microscopy
#7
Priscila Giavedoni, Marnie Ririe, Cristina Carrera, Susana Puig, Josep Malvehy
Li-Fraumeni syndrome (LFS) is a rare autosomal dominant disorder caused by a mutation in the p53 gene. Melanoma is considered to be a rare, controversial component of LFS. The aim of this study is to describe the utility of systematic screening for melanoma in patients with LFS and atypical mole syndrome. Two 28-year-old identical twin sisters with LFS and atypical moles were monitored by physical examination, total-body digital photography and dermoscopy be-tween 2006 and 2014. A total of 117, predominantly dark-brown, reticular naevi were identified on case 1 and 105 on case 2...
February 20, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28217488/dermoscopy-of-erythema-multiforme
#8
Feroze Kaliyadan
No abstract text is available yet for this article.
January 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28212774/using-a-chalazion-clamp-to-enhance-dermoscopy-of-oral-mucosal-lesions
#9
Abhijeet Kumar Jha, Juhi Pathak
No abstract text is available yet for this article.
March 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28196618/dermoscopic-features-predicting-the-presence-of-mitoses-in-thin-melanoma
#10
S Ribero, G Argenziano, A Lallas, E Moscarella, E Benati, M Raucci, S Piana, C Longo
BACKGROUND: The latest AJCC classification has included the number of mitoses as a factor for upstaging thin melanomas. Meanwhile, while dermoscopy has often been used to predict melanoma thickness, its value in predicting number of mitoses remains unknown. OBJECTIVE: Our aim is to evaluate the correlation between dermoscopic features and the presence of mitoses in a consecutive cohort of thin melanomas. METHODS: A case control study has been performed to identify specific dermoscopic parameters that could differentiate thin melanomas with 1 or more mitoses per mm2 from those without mitoses...
February 3, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28191689/non-invasive-skin-imaging-for-the-diagnosis-of-myiasis
#11
E Cinotti, B Labeille, F Cambazard, F Dupuis, P Rubegni, J L Perrot
A 52-year-old man presented with a painful ulceration of the scalp (Fig. 1a). He had returned from Guyana the previous week. Dermoscopic examination (FotoFinder Systems GmbH, Bad Birnbach, Germany) showed an intermittent dynamic aspect changing from a sanguineous roundish ulcer (Fig. 1b) to a peculiar roundish structure characterized by a yellowish peripheral ring and a central brownish part (Fig. 1c). High-definition optical coherence tomography (HD-OCT; Skintell(®) ; Agfa Gevaert, Antverpen, Belgium) showed a skin cavity (Fig...
February 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28191686/dermoscopy-of-uncommon-variants-of-dermatofibrosarcoma-protuberans
#12
Claudia Costa, Milena Cappello, Giuseppe Argenziano, Vincenzo Piccolo, Massimiliano Scalvenzi
Darier-Ferrand dermatofibrosarcoma protuberans (DFSP) is a locally aggressive fibrohistiocytic tumour with a low metastatic potential.(1) Because of its rarity, slow progression and lack of early clinical clues, the diagnosis of DFSP is often delayed. Classical DFSP clinically appeared like an indurated, irregularly-shaped plaques exhibiting flesh to reddish-brown colour. Some lesions also showed thin teleangectasia on the surface (Fig. 1, a). This article is protected by copyright. All rights reserved.
February 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28191661/combined-in-vivo-reflectance-confocal-microscopy-and-digital-dermoscopy-for-follow-up-of-patients-at-high-risk-of-malignant-melanoma-a-prospective-case-series-study
#13
Uxúa Floristán Muruzábal, Reyes Gamo Villegas, Ana Pampín Franco, Fernando Pinedo Moraleda, Elia Pérez Fernández, José Luis López-Estebaranz
Digital dermoscopy (DD) follow up is a useful strategy for monitoring patients at high risk of melanoma. Reflectance confocal microscopy (RCM) is a valuable second-level examination after dermoscopy for the evaluation of difficult to diagnose lesions. The aim of this study was to assess the value of RCM in routine DD monitoring of patients at high risk of melanoma. In this prospective study, performed over 22 months, changing melanocytic lesions were detected by DD and excised. RCM imaging was performed before surgical excision of all the lesions, and histopathology used as the gold standard diagnostic test...
February 13, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28150346/dermoscopic-features-of-nail-psoriasis-treated-with-biologics
#14
Yuki Hashimoto, Miki Uyama, Yuko Takada, Kenji Yoshida, Akira Ishiko
Although psoriatic nail lesions are small, they cause considerable discomfort for patients and adversely affect quality of life. Few studies have evaluated the dermoscopic features of psoriatic nails. The aim of this study was to clarify the dermoscopic features of nail psoriasis and identify those that reflect psoriatic activity. During biologic treatment of psoriasis, six patients with psoriatic nails twice underwent dermoscopic examination, with an interval of 17-42 weeks. We used the modified Nail Psoriasis Severity Index score and Psoriasis Area and Severity Index score to identify and assess dermoscopic features...
February 2, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28132411/a-case-report-of-disappearing-pigmented-skin-lesions-associated-with-pembrolizumab-treatment-for-metastatic-melanoma
#15
Z J Wolner, A A Marghoob, M P Pulitzer, M A Postow, M A Marchetti
Pembrolizumab is an immune checkpoint inhibitor that targets the programmed cell death (PD)-1 receptor. Common cutaneous adverse side effects of PD-1 inhibitors include maculopapular rash, pruritus, vitiligo, and lichenoid skin and mucosal reactions. Here, we describe a man in his sixties with metastatic melanoma treated with pembrolizumab who subsequently developed fading or disappearance of pigmented skin lesions, lightening of the skin, and poliosis of the eyebrows, eyelashes, and scalp and body hair. Compared to baseline high-resolution three-dimensional total body photography, we observed fading or disappearing of solar lentigines, seborrheic keratoses, and melanocytic naevi, suggesting that PD-1 inhibitors may affect the evolution of these benign skin lesions...
January 28, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28128081/dermoscopic-findings-in-patients-with-pigmented-purpuric-dermatoses
#16
Seray Külcü Çakmak, Arzu Kılıç, Ahu Yorulmaz, Duru Onan, Derya Yayla, Ferda Artüz
Pigmented purpuric dermatoses (PPD) are a group of chronic and relapsing cutaneous disorders characterized by a distinct purpuric rash. The diagnosis is made with clinical and histopathological findings. Dermoscopy has rarely been used in the diagnosis of PPD. The aim of our study is to describe the dermoscopic findings in patients with PPD. Eighteen patients who were clinically and histopathologically diagnosed with PPD were studied prospectively. The type and duration of PPD, associated diseases, and medication history of the patients were noted...
December 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28121084/melanoma-clinical-and-dermoscopic-diagnosis
#17
Gabriella Brancaccio, Teresa Russo, Aimilios Lallas, Elvira Moscarella, Marina Agozzino, Giuseppe Argenziano
Missing the diagnosis of a melanoma is the worst dermatologist nightmare, especially when melanomas have a non-alarming clinical appearance and imitate a completely benign lesion. The use of dermoscopy has provided an effective tool to facilitate the differential diagnosis and to increasingly allow an early diagnosis of melanoma. The aim of this article is to summarize the most recent and important clinical and dermoscopic pearls to recognize melanoma at the earliest stages of its development.
January 24, 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28118479/update-on-dermoscopy-of-spitz-reed-naevi-and-management-guidelines-by-the-international-dermoscopy-society
#18
REVIEW
A Lallas, Z Apalla, D Ioannides, E Lazaridou, A Kyrgidi, P Broganelli, R Alfano, I Zalaudek, G Argenziano
Spitzoid lesions represent a challenging and controversial group of tumours, in terms of clinical recognition, biologic behavior and management strategies. Although Spitz naevi are considered benign tumours, their clinical and dermoscopic morphologic overlap with spitzoid melanoma renders the management of spitzoid lesions particularly difficult. The controversy deepens because of the existence of tumours that cannot be safely histopathologically diagnosed as naevi or melanomas (atypical Spitz tumours). The dual objective of the present study was to provide an updated classification on dermoscopy of Spitz naevi, and management recommendations of spitzoid looking lesions based on a consensus among experts in the field...
January 24, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28111793/dermoscopy-of-papular-epidermal-nevus-with-skyline-basal-cell-layer
#19
Riccardo Balestri, Laura Rizzoli, Giulia Rech, Carlo Renè Girardelli
Papular epidermal nevus with skyline basal cell layer (PENS) is a newly described keratinocytic nevus whose dermoscopic characteristics have not been clarified. We used a dermatoscope to investigate the multiple PENSs of a patient with PENS syndrome. All the lesions shared a common dermoscopic homogeneous white pattern surrounded by peripheral, slightly dotted hyperpigmentation. The smallest lesions had no other features, whereas the largest lesions had some scaling, directly proportional to their dimension, and a central, clear, pink discoloration...
January 23, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28109068/the-impact-of-dermoscopy-on-melanoma-detection-in-the-practice-of-dermatologists-in-europe-results-of-a-pan-european-survey
#20
A M Forsea, P Tschandl, I Zalaudek, V Del Marmol, H P Soyer, G Argenziano, A C Geller
BACKGROUND: Dermoscopy is a widely used technique that can increase the sensitivity and specificity of melanoma detection. Information is lacking on the impact of dermoscopy use on the detection of melanoma in the real-life practice of European dermatologists. OBJECTIVE: To identify factors that influence the benefit of using dermoscopy for increasing melanoma detection and lowering the number of unnecessary biopsies in the practice of European dermatologists. METHODS: We conducted a survey of dermatologists registered in 32 European countries regarding: the demographic and practice characteristics, dermoscopy training and use, opinions on dermoscopy and the self-estimated impact of dermoscopy use on the number of melanomas detected and the number of unnecessary biopsies performed in practice...
January 21, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
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