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Marina Venturini, Arianna Zanca, Ausilia Maria Manganoni, Laura Pavoni, Giulio Gualdi, PierGiacomo Calzavara-Pinton
No abstract text is available yet for this article.
November 2016: Journal of the American Academy of Dermatology
C Navarrete-Dechent, F Fich, S Gonzalez
Trichomycosis (Trichobacteriosis) is an asymptomatic, superficial infection, caused by a corenyform-actinomycetes bacterium. Though classically affecting the armpits, when affecting atypical locations, such as the scalp or genitals, naked eye examination is vague with a broad differential diagnosis. This article is protected by copyright. All rights reserved.
October 14, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
Kohei Nojima, Takeshi Namiki, Shown Tokoro, Keiko Miura, Hiroo Yokozeki
An early and accurate diagnosis is critical for the optimal management of subungual melanoma; the absence of Hutchinson's nail sign makes an accurate diagnosis extremely difficult. Previous publications show that most subungual melanomas have Hutchinson's nail sign. In this report, we present a rare case of a subungual melanoma without Hutchinson's nail sign and discuss the importance of cautious evaluations of Hutchinson's nail sign by dermoscopy.
October 12, 2016: Australasian Journal of Dermatology
Abhijeet K Jha, Sidharth Sonthalia, Rashmi Sarkar
No abstract text is available yet for this article.
September 2016: Indian Dermatology Online Journal
Ajay K Rai
No abstract text is available yet for this article.
September 2016: Indian Dermatology Online Journal
Nigel G Maher, Annalisa Solinas, Richard A Scolyer, Pascale Guitera
OBJECTIVE: To improve prebiopsy diagnostic accuracy and surgical management of pigmented appearing lesions on the lips, particularly melanoma, using in vivo reflectance confocal microscopy (RCM). STUDY DESIGN: Prospective case series over a 12-month period between 2015 and 2016. The setting was two specialist dermatology referral centers with expertise in confocal microscopy. The study population was a consecutive sample of patients with pigmentation of the lip for which the cause was uncertain clinically, whose differential diagnosis included melanoma, and who had undergone both in vivo RCM and subsequent biopsy...
August 24, 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
G Richtig, L Byrom, R Kupsa, H Schaider, R Hofmann-Wellenhof, I H Wolf, H P Soyer, E Richtig
Whether or not pregnancy favours the occurrence and growth of melanoma is a source of controversy in the literature. Several case reports have shown dramatic courses of diseases in pregnancy. We present a case of a 36-year-old woman with multiple naevi with one melanoma detected in 2009 in the first trimester and a second primary melanoma in 2010 in the third trimester of her pregnancy. Both lesions have been present for at least 5 years and have been interpreted as dysplastic naevi. Because of their growth during pregnancy they were removed...
October 8, 2016: British Journal of Dermatology
E Benati, S Ribero, C Longo, S Piana, S Puig, C Carrera, F Cicero, H Kittler, T Deinlein, I Zalaudek, W Stolz, A Scope, G Pellacani, E Moscarella, B M Piraccini, M Starace, G Argenziano
BACKGROUND: Longitudinal melanonychia might be difficult to differentiate and the use of dermoscopy can be useful for the preoperative evaluation and management decision. OBJECTIVES: The aim of our study was to investigate clinical and dermoscopic criteria of acquired longitudinal melanonychia in adults to identify the best predictors of melanoma using a multivariate analysis and to explore eventual new dermoscopic criteria for nail melanoma diagnosis. METHODS: In this retrospective observational study, 82 histopathologically diagnosed, acquired nail pigmented bands were collected and examined...
October 1, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
Eunice Song, Jane M Grant-Kels, Helen Swede, Jody L D'Antonio, Avery Lachance, Soheil S Dadras, Arni K Kristjansson, Katalin Ferenczi, Hanspaul S Makkar, Marti J Rothe
BACKGROUND: Several technologies have been developed to aid dermatologists in the detection of melanoma in vivo including dermoscopy, multispectral digital skin lesion analysis (MDSLA), and reflectance confocal microscopy (RCM). To our knowledge, there have been no studies directly comparing MDSLA and RCM. OBJECTIVE: We conducted a repeated measures analysis comparing the sensitivity and specificity of MDSLA and RCM in the detection of melanoma (n = 55 lesions from 36 patients)...
September 29, 2016: Journal of the American Academy of Dermatology
Syril Keena T Que, Jane M Grant-Kels, Harold S Rabinovitz, Margaret Oliviero, Alon Scope
The clinical diagnosis of tumors on the curved surfaces of the face, around the eyes, and on the mucosal surfaces can be difficult, while biopsies and excisions can have functional and aesthetic consequences. To avoid unnecessary surgery, clinicians have been aiming to attain accurate noninvasive diagnosis of lesions at these sites. However, acquisition of high-quality images with dermoscopy and with traditional wide-probe reflectance confocal microscopy (WP-RCM) have been hampered with technical difficulties...
October 2016: Dermatologic Clinics
Phoebe Star, Pascale Guitera
Distinguishing lentigo maligna (LM) and lentigo maligna melanoma (LMM) from background pigmented non-melanoma lesions is challenging. The field of solar damage can obscure clinical assessment, and diagnostic ambiguities are created due to the overlap of the clinical features of LM with other benign lesions. Moreover, margin assessment on histology is limited by the resemblance between melanocytic hyperplasia of actinically damaged skin and scattered atypical melanocytes of LM/LMM. Dermoscopy has made a significant contribution but is often not sufficient for diagnosis and margin assessment...
October 2016: Dermatologic Clinics
Cristina Carrera, Ashfaq A Marghoob
Reflectance confocal microscopy (RCM) together with dermoscopy enables improved differentiation of melanomas from most nevi. The resulting high sensitivity for detecting melanoma with RCM is complemented by a concomitant increased specificity, which results in the reduction of unnecessary biopsies of nevi. Although RCM can achieve high diagnostic accuracy for early melanoma detection, false-negative and false-positive cases of melanoma are occasionally encountered. This article reviews the essential clues and pitfalls for the diagnosis of melanoma via RCM and highlights the importance of evaluating RCM findings in light of the clinical scenario and dermoscopic features...
October 2016: Dermatologic Clinics
Syril Keena T Que, Jane M Grant-Kels, Caterina Longo, Giovanni Pellacani
The use of reflectance confocal microscopy (RCM) and other noninvasive imaging devices can potentially streamline clinical care, leading to more precise and efficient management of skin cancer. This article explores the potential role of RCM in cutaneous oncology, as an adjunct to more established techniques of detecting and monitoring for skin cancer, such as dermoscopy and total body photography. Discussed are current barriers to the adoption of RCM, diagnostic workflows and standards of care in the United States and Europe, and medicolegal issues...
October 2016: Dermatologic Clinics
Caterina Longo, Francesca Specchio, Simone Ribero, Valeria Coco, Athanassios Kyrgidis, Elvira Moscarella, Moira Ragazzi, Ketty Peris, Giuseppe Argenziano
BACKGROUND: Several dermoscopic criteria for diagnosing BCC have been identified over the last years with the aim to help recognition of the tumour among others entities. However, few literature data are available regarding the identification of specific diagnostic criteria of small size BCCs OBJECTIVES: the aims of this study were 1) to investigate whether small size BCCs (<5 mm) are typified by specific dermoscopic criteria compared to larger BCCs (>5 mm) in a consecutive cohort of excised lesions and 2) to explore whether small BCCs belong to distinct histologic subtype METHODS: Histopathologically proven BCCs with a full set of clinical and dermoscopic images were retrieved in order to have a case-control study of small (<5mm in size) and large (>5mm in size) tumors...
September 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
P Huet, G Barnéon, B Cribier
No abstract text is available yet for this article.
September 24, 2016: Annales de Dermatologie et de Vénéréologie
Eric Ehrsam, Joseph R Kallini, Damien Lebas, Amor Khachemoune, Philippe Modiano, Hervé Cotten
Fully regressive melanoma is a phenomenon in which the primary cutaneous melanoma becomes completely replaced by fibrotic components as a result of host immune response. Although 10 to 35 percent of cases of cutaneous melanomas may partially regress, fully regressive melanoma is very rare; only 47 cases have been reported in the literature to date. AH of the cases of fully regressive melanoma reported in the literature were diagnosed in conjunction with metastasis on a patient. The authors describe a case of fully regressive melanoma without any metastases at the time of its diagnosis...
August 2016: Journal of Clinical and Aesthetic Dermatology
Richard R Winkelmann, Aaron S Farberg, Natalie Tucker, Richard White, Darrell S Rigel
BACKGROUND: Early detection and subsequent management of melanoma are critical for patient survival. New technologies have been developed to augment clinician analysis of suspicious pigmented skin lesions. OBJECTIVE: To determine how information provided by a multispectral digital skin lesion analysis device affects the biopsy decisions of international dermatologists following clinical and dermoscopic pigmented skin lesion evaluation. METHODS: Participants at a dermoscopy conference in Vienna, Austria, were shown 12 clinical and dermoscopic images of pigmented skin lesions (2 melanomas in situ, 3 invasive melanomas, and 7 low-grade dysplastic nevi) previously analyzed by multispectral digital skin lesion analysis...
July 2016: Journal of Clinical and Aesthetic Dermatology
Muhsin A Al-Dhalimi, Murtadha H Al-Janabi
BACKGROUND: Lasers have been the treatment of choice for Port-wine stain (PWS). However, only one type of laser is not a panacea for all PWS malformations. This is may be due to the great heterogeneity of phenotypic presentation of this congenital anomaly as color, depth, and the site of the lesion. For the treatment of PWS, flash lamp-pumped pulsed dye laser, carbon dioxide, argon, krypton, copper bromide, frequency-doubled neodymium:yttrium-aluminum-garnet (Nd:YAG), and also intense pulsed light sources can be used...
September 26, 2016: Lasers in Surgery and Medicine
Lauren M Madigan, German Treyger, Laurie L Kohen
BACKGROUND: For even seasoned practitioners, early melanomas can be difficult to distinguish from melanocytic nevi. Although serial digital dermoscopy is considered by many to be the gold standard for monitoring patients at high risk, poor compliance can seriously alter efficacy. In 2014, a concerning compliance rate of 25% was reported from a single, private clinic. Information is currently limited regarding the determinants of compliance and whether patients at high risk return at an acceptable rate...
September 21, 2016: Journal of the American Academy of Dermatology
Zorica Đorđević Brlek, Ružica Jurakić Tončić, Jaka Radoš, Branka Marinović
Nodular melanoma is the most aggressive subtype of melanoma, with rapid growth rate and metastatic potential. It is usually diagnosed at a locally advanced stage (Breslow thickness <2 mm) and is therefore associated with a poor prognosis. Nodular melanoma often does not fit the classic clinical ABCD criteria, but rather the EFG rule or 3 Cs criteria. Missing the diagnosis of nodular melanoma is a dermatologist's worst nightmare, especially since nodular melanomas can have a non-alarming clinical appearance and imitate a wide range of benign lesions...
August 2016: Acta Dermatovenerologica Croatica: ADC
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