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https://www.readbyqxmd.com/read/27870908/n-terminal-pro-b-type-natriuretic-peptide-as-a-biomarker-for-loss-of-muscle-mass-in-prevalent-hemodialysis-patients
#1
Misa Ikeda, Hirokazu Honda, Keiko Takahashi, Kanji Shishido, Takanori Shibata
Protein-energy wasting (PEW) is common in hemodialysis (HD) patients. A recent study demonstrated that a high level of N-terminal pro-B-type natriuretic peptide (NT-proBNP) may be associated with PEW in those patients. This prospective study aimed to assess the association of NT-proBNP with body composition and muscle loss. A cohort of prevalent HD patients (n = 238) was examined. Blood samples were obtained at baseline to measure high-sensitive C-reactive protein (hsCRP), interleukin-6 (IL-6), adiponectin and NT-proBNP...
2016: PloS One
https://www.readbyqxmd.com/read/27843947/relationship-between-interdialytic-weight-gain-and-blood-pressure-in-pediatric-patients-on-chronic-hemodialysis
#2
Olivera Marsenic, Michael Anderson, Kevin G Couloures
Overhydration is reported to be the main cause of hypertension (HTN) as well as to have no association with HTN in hemodialysis (HD) population. This is the first report of the relationship between interdialytic weight gain (IDWG) and pre-HD blood pressure (BP) in pediatric patients in relation to residual urine output (RUO). We studied 170 HD sessions and interdialytic periods performed during a 12-week period in 5 patients [age 4-17 years, weight 20.8-66 kg, 3 anuric (102 HD sessions), and 2 nonanuric (68 HD sessions)]...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27834525/protecting-vulnerable-skin-from-moisture-associated-skin-damage
#3
Mark Collier, Debbie Simon
The skin, the body's largest organ, has several functions. Its barrier role can be undermined if it is in contact with urine, faeces and other sources of excess moisture; overhydration can also increase the likelihood of injury from friction through contact with clothing, incontinence pads or bed linen. If skin has been damaged by moisture or is at risk of this, its health can be supported through cleansing to maintain its acid mantle followed by protection with barrier products. Barrier preparations are available in different forms, and their effectiveness varies...
November 10, 2016: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/27734218/the-importance-of-residual-renal-function-in-peritoneal-dialysis
#4
Dorota Sikorska, Krzysztof Pawlaczyk, Anna Olewicz-Gawlik, Natasza Czepulis, Bartlomiej Posnik, Ewa Baum, Maria Wanic-Kossowska, Bengt Lindholm, Andrzej Oko
BACKGROUND: Peritoneal dialysis (PD) patients with preserved residual diuresis have a lower risk of death and complications. Here we analyzed associations between residual diuresis and presence of fluid overload and biomarkers of cardiac strain and nutrition in PD patients. METHODS: Among 44 PD patients placed into three subgroups, depending on volume of residual diuresis (group A ≤ 500; group B 600-1900; and group C ≥ 2000 mL/day), we examined: overhydration (OH) assessed by bioimpedance analysis (BIA; yielding OH index OHBIA) and by clinical criteria (edema and hypertension); nutritional status (by subjective global assessment, SGA); metabolic status (electrolytes, serum lipid profile, CRP, and albumin); biomarkers of fluid overload and cardiac strain (N-terminal probrain natriuretic peptide, NT-proBNP, and troponin T, TnT); and, echocardiography and chest X-ray...
December 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27677366/changes-in-body-composition-following-haemodialysis-as-assessed-by-bioimpedance-spectroscopy
#5
K Tangvoraphonkchai, A Davenport
BACKGROUND/OBJECTIVES: Patients with chronic kidney disease treated by haemodialysis (HD) are at increased risk of sarcopenia. Bioelectrical impedance spectroscopy (BIS) can be used to determine body composition, and is one of the several potential screening tools for sarcopenia. The newer generation of portable hand-held devices can be readily used in dialysis centres. The results from BIS devices using a two-compartmental model of body composition can be affected by hydration status and so ideally measurements should be made when patients are not overhydrated...
September 28, 2016: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27659663/direct-cardiac-involvement-in-childhood-hemolytic-uremic-syndrome-case-report-and-review-of-the-literature
#6
Davide Rigamonti, Giacomo D Simonetti
: Overhydration, hypertension, anemia, or dyselectrolytemias sometimes cause cardiovascular impairment in childhood hemolytic-uremic syndrome. Here, we report the case of a 4.5-year-old boy with hemolytic-uremic syndrome and sudden onset, 6 h later, of hemodynamic compromise secondary to a cardiac thrombotic micro-angiopathy. The child died. In the literature, we found 18 further cases with cardiac compromise ≤25 days after diagnosis. The following causes were found: micro-angiopathy, pericardial blood causing tamponade, and myocarditis...
September 23, 2016: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27648408/is-overhydration-in-peritoneal-dialysis-patients-associated-with-cardiac-mortality-that-might-be-reversible
#7
Elizabeth Oei, Klara Paudel, Annemarie Visser, Hazel Finney, Stanley L Fan
AIM: To study the relationship between overhydration (OH) in peritoneal dialysis (PD) patients and cardiac mortality. METHODS: OH, as measured by body composition monitor (BCM), is associated with increased mortality in dialysis patients. BCM has been used to guide treatment on the assumption that correcting OH will improve cardiac morbidity and mortality although data demonstrating causality that is reversible is limited. We wished to determine if OH in PD patients predicted cardiac mortality, and if there was a correlation between OH and cardiac troponin-T (cTnT) levels...
September 6, 2016: World Journal of Nephrology
https://www.readbyqxmd.com/read/27647998/overhydration-negatively-affects-quality-of-life-in-peritoneal-dialysis-patients-evidence-from-a-prospective-observational-study
#8
Hye Eun Yoon, Young Joo Kwon, Ho Cheol Song, Jin Kuk Kim, Young Rim Song, Seok Joon Shin, Hyung Wook Kim, Chang Hwa Lee, Tae Won Lee, Young Ok Kim, Byung Soo Kim, Kyoung Hyoub Moon, Yoon Kyung Chang, Seong Suk Kim, Kitae Bang, Jong Tae Cho, Sung Ro Yun, Ki Ryang Na, Yang Wook Kim, Byoung Geun Han, Jong Hoon Chung, Kwang Young Lee, Jong Hyeok Jeong, Eun Ah Hwang, Yong-Soo Kim
UNLABELLED: Backgound: This study evaluated whether the hydration status affected health-related quality of life (HRQOL) during 12 months in peritoneal dialysis (PD) patients. METHODS: The hydration status and the HRQOL were examined at baseline and after 12 months using a bioimpedance spectroscopy and Kidney Disease Quality of Life-Short Form, respectively in PD patients. Four hundred eighty-one patients were included and divided according to the baseline overhydration (OH) value; normohydration group (NH group, -2L≤ OH ≤+2L, n=266) and overhydration group (OH group, OH >+2L, n=215)...
2016: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/27575931/echocardiographic-findings-in-haemodialysis-patients-according-to-their-state-of-hydration
#9
María Cristina Di Gioia, Raul Gascuena, Paloma Gallar, Gabriela Cobo, Rosa Camacho, Nuria Acosta, Zsofia Baranyi, Isabel Rodriguez, Aniana Oliet, Olimpia Ortega, Inmaculada Fernandez, Carmen Mon, Milagros Ortiz, Mari C Manzano, Juan C Herrero, José I Martinez, Joaquín Palma, Ana Vigil
BACKGROUND: Chronic fluid overload is frequent in hemodialysis patients (P) and it associates with hypertension, left ventricular hypertrophy (LVH) and higher mortality. Moreover, echocardiographic data assessing fluid overload is limited. Our aim was to evaluate the relationship between fluid overload measured by bioimpedance spectroscopy (BIS) and different echocardiographic parameters. METHODS: Cross-sectional observational study including 76 stable patients...
August 26, 2016: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/27548748/are-we-being-drowned-by-overhydration-advice-on-the-internet
#10
Martin D Hoffman, Theodore L Bross, R Tyler Hamilton
OBJECTIVE: Because inappropriate recommendations about hydration during exercise appear widespread and potentially dangerous, we assessed the quality of a sampling of information currently available to the public on the Internet. METHODS: Internet searches using the Google search engine were conducted using the terms "hydration," "hydration guidelines," "drinking fluids" and "drinking guidelines" combined with "and exercise." From the first 50 websites for each search phrase, duplicates were removed yielding 141 unique websites that were categorized by source and examined for specific hydration related information and recommendations...
August 22, 2016: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/27515857/pre-dialysis-and-post-dialysis-hydration-status-and-n-terminal-pro-brain-natriuretic-peptide-and-survival-in-haemodialysis-patients
#11
Kamonwan Tangvoraphonkchai, Andrew Davenport
PURPOSE: Many dialysis centres have no formal program for assessing and adjusting post-haemodialysis (HD) target weight. Apart from clinical assessment, there are bioimpedance devices and natriuretic peptides that could potentially aid clinical management. We wished to determine whether pre- or post-HD bioimpedance assessment of extracellular water (ECW) or N terminal probrain natriuretic peptide (NT-proBNP) affected patient outcomes. METHODS: Multi-frequency bioimpedance assessments (MFBIA) were made before and after the midweek dialysis session, along with a post-dialysis NT-proBNP measurement...
August 19, 2016: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/27497672/pulmonary-function-in-patients-with-end-stage-renal-disease-effects-of-hemodialysis-and-fluid-overload
#12
Süreyya Yılmaz, Yasar Yildirim, Zülfükar Yilmaz, Ali Veysel Kara, Mahsuk Taylan, Melike Demir, Mehmet Coskunsel, Ali Kemal Kadiroglu, Mehmet Emin Yilmaz
BACKGROUND Respiratory system disorders are one of the most prevalent complications in end-stage renal disease patients on hemodialysis. However, the pathogenesis of impaired pulmonary functions has not been completely elucidated in these patients. We designed a study to investigate acute effects of hemodialysis treatment on spirometry parameters, focusing on the relationship between pulmonary function and fluid status in hemodialysis patients. MATERIAL AND METHODS We enrolled 54 hemodialysis patients in this study...
2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27478611/intradialytic-hypertension-during-chronic-haemodialysis-and-subclinical-fluid-overload-assessed-by-bioimpedance-spectroscopy
#13
Sajith Sebastian, Christelle Filmalter, Justin Harvey, Mogamat-Yazied Chothia
BACKGROUND: Intradialytic hypertension (IDH) increases morbidity and mortality. The prevalence in South Africa is unknown. The pathogenesis is unclear, but it has been suggested that IDH may be due to subclinical fluid overload. The objective of this study was to determine the prevalence of IDH and to evaluate its association with fluid overload using bioimpedance spectroscopy (BIS). METHODS: A cross-sectional study involving 190 chronic haemodialysis patients in the Western Cape province of South Africa was conducted between January 2013 and May 2014...
August 2016: Clinical Kidney Journal
https://www.readbyqxmd.com/read/27452672/adropin-and-irisin-levels-in-relation-to-nutrition-body-composition-and-insulin-resistance-in-patients-with-end-stage-renal-disease-on-chronic-hemodialysis-and-peritoneal-dialysis
#14
Małgorzata Kałużna, Krzysztof Hoppe, Krzysztof Schwermer, Aisha Y Ibrahim, Krzysztof Pawlaczyk, Katarzyna Ziemnicka
INTRODUCTION    Newly discovered myokines, adropin, and irisin, are regulators of energy homeostasis and metabolism in humans. In end-stage renal disease (ESRD), the significance and role of irisin and adropin as metabolism regulators are still unclear. OBJECTIVES    The aim of this study was to evaluate serum adropin and irisin levels and establish their relation to insulin resistance, nutritional status, and hydration status in patients on chronic hemodialysis (HD) and on peritoneal dialysis (PD). PATIENTS AND METHODS    The study consisted of 71 subjects, including 48 patients (18 women, 30 men; median age, 56...
July 25, 2016: Polskie Archiwum Medycyny Wewnętrznej
https://www.readbyqxmd.com/read/27415758/overhydration-is-a-strong-predictor-of-mortality-in-peritoneal-dialysis-patients-independently-of-cardiac-failure
#15
Valérie Jotterand Drepper, Lars P Kihm, Florian Kälble, Christian Diekmann, Joerg Seckinger, Claudia Sommerer, Martin Zeier, Vedat Schwenger
BACKGROUND: Overhydration is a common problem in peritoneal dialysis patients and has been shown to be associated with mortality. However, it still remains unclear whether overhydration per se is predictive of mortality or whether it is mainly a reflection of underlying comorbidities. The purpose of our study was to assess overhydration in peritoneal dialysis patients using bioimpedance spectroscopy and to investigate whether overhydration is an independent predictor of mortality. METHODS: We analyzed and followed 54 peritoneal dialysis patients between June 2008 and December 2014...
2016: PloS One
https://www.readbyqxmd.com/read/27402760/akap220-manages-apical-actin-networks-that-coordinate-aquaporin-2-location-and-renal-water-reabsorption
#16
Jennifer L Whiting, Leah Ogier, Katherine A Forbush, Paula Bucko, Janani Gopalan, Ole-Morten Seternes, Lorene K Langeberg, John D Scott
Filtration through the kidney eliminates toxins, manages electrolyte balance, and controls water homeostasis. Reabsorption of water from the luminal fluid of the nephron occurs through aquaporin-2 (AQP2) water pores in principal cells that line the kidney-collecting duct. This vital process is impeded by formation of an "actin barrier" that obstructs the passive transit of AQP2 to the plasma membrane. Bidirectional control of AQP2 trafficking is managed by hormones and signaling enzymes. We have discovered that vasopressin-independent facets of this homeostatic mechanism are under the control of A-Kinase Anchoring Protein 220 (AKAP220; product of the Akap11 gene)...
July 26, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27377748/the-influence-of-environmental-variables-on-platelet-concentration-in-horse-platelet-rich-plasma
#17
Riccardo Rinnovati, Noemi Romagnoli, Fabio Gentilini, Carlotta Lambertini, Alessandro Spadari
Platelet-rich plasma (PRP) commonly refers to blood products which contain a higher platelet (PLT) concentration as compared to normal plasma. Autologous PRP has been shown to be safe and effective in promoting the natural processes of soft tissue healing or reconstruction in humans and horses. Variability in PLT concentration has been observed in practice between PRP preparations from different patients or from the same individual under different conditions. A change in PLT concentration could modify PRP efficacy in routine applications...
2016: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/27371776/preliminary-observations-on-the-association-between-serum-il-6-and-hydration-status-and-cardiovascular-risk-in-patients-treated-with-peritoneal-dialysis
#18
Dorota Sikorska, Krzysztof Pawlaczyk, Magdalena Roszak, Natasza Czepulis, Andrzej Oko, Marek Karczewski, Andrzej Breborowicz, Janusz Witowski
INTRODUCTION: Systemic inflammation, as defined by elevated blood IL-6, is a strong independent predictor of peritoneal dialysis (PD) patient survival. The present study has aimed to determine whether there exists a particular "phenotype" associated with high systemic IL-6 that characterizes PD patients in terms of their fluid status and cardiac parameters. METHODS: Fifty-seven prevalent PD patients were classified according to serum concentrations of IL-6. The degree of overhydration was assessed by bioimpedance analysis (BIA)...
September 2016: Cytokine
https://www.readbyqxmd.com/read/27353637/advances-in-understanding-the-pathogenesis-of-the-red-cell-volume-disorders
#19
REVIEW
Catherine Badens, Hélène Guizouarn
Genetic defects of erythrocyte transport proteins cause disorders of red blood cell volume that are characterized by abnormal permeability to the cations Na(+) and K(+) and, consequently, by changes in red cell hydration. Clinically, these disorders are associated with chronic haemolytic anaemia of variable severity and significant co-morbidities, such as iron overload. This review provides an overview of recent insights into the molecular basis of this group of rare anaemias involving cation channels and transporters dysfunction...
September 2016: British Journal of Haematology
https://www.readbyqxmd.com/read/27346666/predialysis-volume-overload-and-patient-reported-sleep-duration-and-quality-in-patients-receiving-hemodialysis
#20
Adrian P Abreo, Lorien S Dalrymple, Glenn M Chertow, George A Kaysen, Charles A Herzog, Kirsten L Johansen
Introduction Previous studies of patients with end-stage renal disease have examined the role of fluid shifts on apnea-hypopnea episodes, but the association between volume overload and patient-reported sleep quality or duration has not been well-established. Methods We studied the association between predialysis bioimpedance spectroscopy-derived volume estimates and self-reported sleep quality and duration in 638 patients in the United States Renal Data System ACTIVE/ADIPOSE study receiving hemodialysis from 2009 to 2011...
June 27, 2016: Hemodialysis International
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