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https://www.readbyqxmd.com/read/29457428/-percutaneous-poking-reduction-with-bone-grafting-and-limited-internal-fixation-for-the-treatment-of-calcaneal-fractures
#1
Hua Chen, Yu-Wei Li, Hong Jiang, Zhi-Gang Zhang, Bin-Jie Lu
OBJECTIVE: To investigate clinical effects of percutaneous poking reduction with bone grafting and limited internal fixation for the treatment of calcaneal fractures. METHODS: From May 2013 to October 2016, 53 patients with closed calcaneal fractures were analyzed, and were divided into treatment group and control group. There were 33 patients in treatment group including 25 males and 8 females, aged from 15 to 82 years old with an average of(44.7±14.2) years old; 17 cases were type II and 16 cases were type III according to Sanders classification; treated by percutaneous poking reduction with bone grafting and limited internal fixation...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29457399/-osseous-bridge-resection-for-the-treatment-of-adult-talocalaneal-coalitions-without-arthritis
#2
Bing Xie, Shuo Yan, Hao Zhang, Yuan-Wei Wang, Jing Tian
OBJECTIVE: To analyze clinical outcomes of osseous-bridge resection for the treatment of adult symptomatic talocalcaneal coalitions without arthritis. METHODS: The clinical data of 12 patients (15 feet) with symptomatic talocalcaneal coalitions without arthtitis from January 2013 to June 2016 were respectively analyzed. All cases were secondary talocalcaneal coalition. There were 9 males (11 feet) and 3 females (4 feet) with a mean (26.6±3.3) years old (ranged, 18 to 33 years old)...
November 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29455065/foot-and-mouth-disease-virus-type-o-specific-mutations-determine-rna-dependent-rna-polymerase-fidelity-and-virus-attenuation
#3
Chen Li, Haiwei Wang, Tiangang Yuan, Andrew Woodman, Decheng Yang, Guohui Zhou, Craig E Cameron, Li Yu
Previous studies have shown that the FMDV Asia1/YS/CHA/05 high-fidelity mutagen-resistant variants are attenuated (Zeng et al., 2014). Here, we introduced the same single or multiple-amino-acid substitutions responsible for increased 3Dpol fidelity of type Asia1 FMDV into the type O FMDV O/YS/CHA/05 infectious clone. The rescued viruses O-DA and O-DAMM are lower replication fidelity mutants and showed an attenuated phenotype. These results demonstrated that the same amino acid substitution of 3Dpol in different serotypes of FMDV strains had different effects on viral fidelity...
February 15, 2018: Virology
https://www.readbyqxmd.com/read/29454975/prefrontal-cortex-activation-during-obstacle-negotiation-what-s-the-effect-size-and-timing
#4
Inbal Maidan, Shiran Shustak, Topaz Sharon, Hagar Bernad-Elazari, Nimrod Geffen, Nir Giladi, Jeffrey M Hausdorff, Anat Mirelman
BACKGROUND: Obstacle negotiation is a daily activity that requires the integration of sensorimotor and cognitive information. Recent studies provide evidence for the important role of prefrontal cortex during obstacle negotiation. We aimed to explore the effects of obstacle height and available response time on prefrontal activation. METHODS: Twenty healthy young adults (age: 30.1 ± 1.0 years; 50% women) walked in an obstacle course while negotiating anticipated and unanticipated obstacles at heights of 50 mm and 100 mm...
February 15, 2018: Brain and Cognition
https://www.readbyqxmd.com/read/29451921/the-effectiveness-of-non-surgical-intervention-foot-orthoses-for-paediatric-flexible-pes-planus-a-systematic-review-update
#5
Sindhrani Dars, Hayley Uden, Helen A Banwell, Saravana Kumar
BACKGROUND: Flexible pes planus (flat feet) in children is a common presenting condition in clinical practice due to concerns amongst parents and caregivers. While Foot Orthoses (FOs) are a popular intervention, their effectiveness remains unclear. Thus, the aim of this systematic review was to update the current evidence base for the effectiveness of FOs for paediatric flexible pes planus. METHODS: A systematic search of electronic databases (Cochrane, Medline, AMED, EMBASE, CINHAL, SportDiscus, Scopus and PEDro) was conducted from January 2011 to July 2017...
2018: PloS One
https://www.readbyqxmd.com/read/29444576/-fractures-of-the-fifth-metatarsal-base
#6
K Bušková, D Kuběnová, M Tuček
Fractures of the fifth metatarsal base are among the most common fractures of the foot. They are typically caused by indirect violence during sports activities. This region is also a site where stress fractures occur frequently. Diagnosis is based on the patients medical history, clinical examination and imaging methods. The fundamental imaging method is radiography of the foot in three views. MRI is used primarily for early diagnosis of stress fractures. CT examination is beneficial mainly in complex foot injuries, in order to rule out associated fractures...
2018: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/29443774/sanders-type-iiiab-calcaneal-fracture-without-broken-lateral-wall-a-case-report-and-review-of-literature
#7
Zhenshuang Yue, Yanghua Tang, Zhongqing Hu, Wenjie Zheng
RATIONALE: The calcaneal fracture without broken lateral wall is rare and the open anatomic reduction and internal fixation (ORIF) is necessary when the subtalar joint articular surface is broken and collapsed. PATIENT CONCERNS: A 45-year-old male was admitted to our department with complaints of heel pain and swelling after falling down from 1-m-high stone. He was unable to bear weight on his right foot. DIAGNOSES: Imaging studies confirmed that it was a sanders type IIIAB calcaneal fracture without broken lateral wall and the middle part of the posterior calcaneal articular facet collapsed...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29441101/high-dose-rate-brachytherapy-in-the-treatment-of-skin-kaposi-sarcoma
#8
María Ángeles González Ruiz, Juan Quirós Rivero, Julia Luisa Muñoz García, Joaquín José Cabrera Rodríguez, Yesika Ríos Kavadoy, María Francisca Ropero Carmona, Almudena Corbacho Campos, Fernando García Urra, María Cristina Cruz Muñoz, Amanda Ruiz Herrero, Pedro Almendral Manzano
Purpose: The aim of the study is to review our experience in treatment of Kaposi sarcoma (KS) lesions with high-dose-rate (HDR) brachytherapy. Material and methods: We present five new KS lesions (three patients) that were treated in our hospital from May 2016 to February 2017 with HDR brachytherapy using Valencia applicators. The treatment was delivered in 5 Gy fractions over five sessions, on alternate days. Total dose of 25 Gy (EQD2 31.25 Gy) was delivered. All patients were male, Caucasian, without a history of HIV, organ transplantation, or current immunosuppressive therapy...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29437059/a-new-and-reliable-classification-system-for-fractures-of-the-navicular-and-associated-injuries-to-the-midfoot
#9
M J Petrie, C M Blakey, C Chadwick, H G Davies, C M Blundell, M B Davies
AIMS: Fractures of the navicular can occur in isolation but, owing to the intimate anatomical and biomechanical relationships, are often associated with other injuries to the neighbouring bones and joints in the foot. As a result, they can lead to long-term morbidity and poor function. Our aim in this study was to identify patterns of injury in a new classification system of traumatic fractures of the navicular, with consideration being given to the commonly associated injuries to the midfoot...
February 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29436863/proinsulin-expressing-dendritic-cells-in-type-2-neuropathic-diabetic-patients-with-and-without-foot-lesions
#10
Maria Sambataro, Luisa Sambado, Enrica Trevisiol, Matilde Cacciatore, Anna Furlan, Piero Maria Stefani, Elena Seganfreddo, Elisabetta Durante, Stefania Conte, Silvia Della Bella, Agostino Paccagnella, Angelo Paolo Dei Tos
Diabetic neuropathy is the most common complication of diabetes and is frequently associated with foot ischemia and infection, but its pathogenesis is controversial. We hypothesized that proinsulin expression in peripheral blood mononuclear cells is a process relevant to this condition and could represent a link among hyperglycemia, nerve susceptibility, and diabetic foot lesions. We assessed proinsulin expression by using flow cytometry in dendritic cells from control participants and patients with type 2 diabetic with or without peripheral neuropathy or accompanied by diabetic foot...
February 12, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29435274/topical-5-potassium-permanganate-solution-accelerates-the-healing-process-in-chronic-diabetic-foot-ulcers
#11
Iván Delgado-Enciso, Violeta M Madrigal-Perez, Agustin Lara-Esqueda, Martha G Diaz-Sanchez, Jose Guzman-Esquivel, Luis E Rosas-Vizcaino, Oscar O Virgen-Jimenez, Juleny Kleiman-Trujillo, Maria R Lagarda-Canales, Gabriel Ceja-Espiritu, Viridiana Rangel-Salgado, Uriel A Lopez-Lemus, Josuel Delgado-Enciso, Agustin D Lara-Basulto, Alejandro D Soriano Hernández
Potassium permanganate has been reported to be an effective treatment for certain types of wounds. The aim of the present study was to evaluate the use of potassium permanganate in the treatment of diabetic foot ulcers. A single-blind, randomized, controlled clinical trial was conducted on patients with type 2 diabetes mellitus that presented with a foot ulcer persisting for >3 months. The control group (n=10) was treated with the current standard treatment, which comprises of measures for reducing pressure in the ulcerated area, daily cleansing of the ulcer with potable water and antiseptic wash solution, and the application of a disinfectant solution on the entire surface area of the ulcer; while the intervention group (n=15) received the standard treatment plus 5% topical potassium permanganate solution applied once a day for 21 days...
February 2018: Biomedical Reports
https://www.readbyqxmd.com/read/29423640/effectiveness-of-custom-made-foot-orthoses-for-treating-forefoot-pain-a-systematic-review
#12
REVIEW
Isabel Arias-Martín, María Reina-Bueno, Pedro V Munuera-Martínez
PURPOSE: Pain in and around the metatarsal heads, the metatarsal phalangeal joints and the surrounding soft tissues is called metatarsalgia. Non-operative treatment of metatarsalgia includes foot orthoses. Foot orthoses may be classified as standard or custom-made. A systematic review was carried out to determine whether custom-made foot orthoses are effective for treating forefoot pain. METHODS: The MEDLINE, CINAHL, The Cochrane Library and PEDro databases were searched for relevant articles reporting patients undergoing treatment for forefoot pain by means of custom-made foot orthoses...
February 8, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29421811/swiprosin-1-promotes-mitochondria-dependent-apoptosis-of-glomerular-podocytes-via-p38-mapk-pathway-in-early-stage-diabetic-nephropathy
#13
Rong-Mei Wang, Zhi-Bin Wang, Yue Wang, Wei-Ye Liu, Ya Li, Ling-Chang Tong, Su Zhang, Ding-Feng Su, Yong-Bing Cao, Ling Li, Li-Chao Zhang
BACKGROUND/AIMS: Podocyte injury, especially podocyte apoptosis, plays a major role in early-stage diabetic nephropathy (DN). Swiprosin-1, also known as EF hand domain containing 2 (EFhd2), is a Ca2+-binding protein in different cell types. However, the function of swiprosin-1 in podocytes remains unknown. METHODS: The expression and distribution of swiprosin-1 were investigated in the mouse renal glomerulus and conditionally immortalized mouse podocyte cell line MPC-5...
February 2, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29417781/-surgical-treatment-for-talar-neck-fracture-of-hawkins-iii-iv-type-with-compression-hollow-screws-combined-with-external-fixator
#14
Xian-Xun Wang, Chang-Tao Wan, Li Yu
OBJECTIVE: To investigate the clinical effects of compression hollow screws combined with external fixator in treating talar neck fracture of Hawkins III, IV type. METHODS: From March 2010 to August 2014, 15 patients with talar neck fractures of Hawkins III, IV type were treated by open reduction and compression hollow screws fixation complicated with external fixator fixation. Including 9 males and 6 females, aged from 17 to 65 years old with an average of 37.5 years old...
May 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29417353/perioperative-management-with-phosphodiesterase-type-5-inhibitor-and-prostaglandin-e1-for-moderate-portopulmonary-hypertension-following-adult-to-adult-living-donor-liver-transplantation-a-case-report
#15
Takashi Onoe, Asuka Tanaka, Kohei Ishiyama, Kentaro Ide, Hirotaka Tashiro, Hideki Ohdan
BACKGROUND: Portopulmonary hypertension (PPH) is a relatively rare but well-recognized complication of end-stage liver disease. Moderate or severe PPH (mean pulmonary artery pressure [mPAP] ≥ 35 mmHg) is usually a contraindication for liver transplantation due to high operation-related mortality. Here, we report on a patient with moderate PPH whose condition was successfully managed with a phosphodiesterase type 5 (PDE5) inhibitor (tadalafil) and prostaglandin E1, who experienced rapid improvement of PPH after living-donor liver transplantation (LDLT)...
February 7, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29415761/direct-serogrouping-of-dichelobacter-nodosus-from-victorian-farms-using-conventional-multiplex-polymerase-chain-reaction
#16
Nickala Best, Jacek Gwozdz, Robert Suter, Grant Rawlin, Travis Beddoe
OBJECTIVE: Dichelobacter nodosus is the causative agent of footrot in sheep. Ovine footrot is a major problem in Australia that results in large economic losses and a represents a very significant animal welfare issue. D. nodosus is divided into 10 serogroups (A-I, M), based on sequence variation in the type IV fimbriae gene, fimA. Control of the bacteria is possible through use of serogroup-specific vaccination, however traditional identification of the serogroups of D. nodosus on infected sheep is time-consuming and costly...
February 7, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29415676/chiari-malformation-type-1-presenting-as-unilateral-progressive-foot-drop-a-case-report-and-review-of-literature
#17
Chamara Jayamanne, Lakkumar Fernando, Sachith Mettananda
BACKGROUND: Foot drop is a disabling clinical condition with multiplicity of causes, which requires detailed evaluation to identify the exact aetiology. Here, we report an extremely rare cause of foot drop in a child, which if not recognized early, could lead to multiple complications. CASE PRESENTATION: A 6-year-old girl presented with difficulty in walking and left sided foot droop for1-month duration. On examination she had reduced muscle power in dorsiflexors and plantar flexors and diminished knee and absent ankle jerk in the left side...
February 7, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29412695/high-injury-burden-in-elite-adolescent-athletes-a-52-week-prospective-study
#18
Philip von Rosen, Annette Heijne, Anna Frohm, Cecilia Friden, Anders Kottorp
CONTEXT:   Our understanding of the injury burden in elite adolescent athletes in most sports is limited or unknown because of the lack of prospective, long-term injury studies. OBJECTIVE:   To describe injury patterns in terms of type, location, prevalence and incidence, recurrence, and severity grade; time to first injury; and prevalence of illness in elite adolescent athletes and to compare differences in injury data by sex and sport type. DESIGN:   Cohort study...
February 7, 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29409278/involvement-of-foot-in-patients-with-spondyloarthritis-prevalence-and-clinical-features
#19
Hana Sahli, Asma Bachali, Raoudha Tekaya, Ines Mahmoud, Yassine Sedki, Olfa Saidane, Leila Abdelmoula
BACKGROUND: The purpose of this study was to evaluate the foot involvement in a group of patients with spondyloarthritis in regard to symptoms, type and frequency of deformities, location and radiological changes. METHODS: We conducted a cross sectional study including 60 patients with spondyloarthritis over a period of six months. Anamnesis, clinical examination, podoscopic examination, biological tests and X-rays of feet were done for each patient. RESULTS: Foot involvement was found in 31 patients (52%)...
November 10, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29409205/clinical-characteristics-and-surgical-experience-of-type-iii-wagstaffe-fractures-pay-attention-to-concomitant-chondral-injury-of-the-talus
#20
Ming Zhang, Yun-Feng Chen, Lei Wang, Fan Li, Hai-Feng Wei, Zhong-Min Shi
BACKGROUND: The purpose of this study was to investigate clinical characteristics and surgical management of Type III Wagstaffe fracture. METHODS: From August 2012 to July 2015, 13 patients with Type III Wagstaffe fractures were surgically treated. During operation, the cartilage of joint surface was explored. Wagstaffe fragment was fixed with cannulated screw or suture, Chaput fragment was fixed with cannulated screw or plate, and Cotton test was performed to evaluate the stability of syndesmosis during the operation...
April 27, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
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