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Hemodynamics excercise

M Christ, J Zange, C P Janson, K Müller, P Kuklinski, B M Schmidt, H C Tillmann, R Gerzer, M Wehling
Non-genomic effects of aldosterone on oxidative metabolism of skeletal muscle have been shown, recently. To further characterize these rapid effects on the increase of phosphocreatine (PCr) in the recovery period after isometric exercise, a randomized cross-over placebo-controlled study was conducted on 9 healthy volunteers. Hypoxia was chosen to test the dependence of the effect on oxygen supply and thus its relation to oxidative vs non-oxidative metabolism. Parameters related to the energy metabolism of calf muscles were measured by 31P magnetic resonance spectroscopy during four repetitive contractions in four different tests (hypoxia [FiO2=0...
September 2001: Journal of Endocrinological Investigation
R S Kronenberg, P Safar, Leej, F Wright, W Noble, E Wahrenbrock, R Hickey, E Nemoto, J W Severinghaus
Pulmonary hemodynamics and gas exchange were studied in four physicians during 72 hr acclimatization to 12,470 ft. Pulmonary catheters were left in three subjects for 72 hr. Resting mean pulmonary arterial pressure (PAP) rose progressively during the first 24 hr from 10.3 +/-1.0 to 21.1 +/-4.0 torr and remained at this level. During this same 24 hr period cardiac output increased from 7.1 +/-1.4 to 8.4 +/-2.0 liters/min and total pulmonary resistance rose from 122 +/-16 to 209 +/-40 dynes.sec/cm(-5). Excercise at 60 w after 24 hr of hypoxia increased PAP to 28...
April 1971: Journal of Clinical Investigation
F De Vito, A Giordano, P Giannuzzi, L Tavazzi
UNLABELLED: Two hundred and forty patients with recent inferior myocardial infarction were studied by a symptom-limited ergometric test with haemodynamic monitoring (triple lumen tip-thermistor Swan-Ganz catheter) in order to investigate and quantify the haemodynamic effects of exercise-induced myocardial ischaemia in post-infarct patients and to assess whether the ST-segment changes give any indication of the degree of ventricular impairment. One hundred and thirteen patients showed no ST-segment changes during excercise; ST-segment elevation in leads with abnormal Q wave occurred in 14 patients, ST-segment depression was recorded in 88 subjects, and both ST-segment elevation and depression were found in 27 patients...
April 1988: European Heart Journal
F V Arsent'ev, V A Barkov, T S Petrukhin
The authors modified the Valsalva test by employing a strictly staged dosed loading with the help of a water manometer for recording rheopneumogrammes in normal individuals and in pulmonary patients. In the absence of clinical signs of cardiac pathology this method permitted to reveal latent disorders in the contractility of the right heart and its reserve capacity. The shifts in the rheographic data of the patients differed significantly from those obtained in the normals. The obtained data indicate that the intrathoracic pressure plays a certain role in the development of pulmonary hypertension...
December 1975: Kardiologiia
S Nitter-Hauge, K V Hall, T Froysaker
A comparison is made between the clinical and haemodynamic results after mitral valve replacement with the Lillehei-Kaster and the Björk-Shiley disc valve prostheses, which were used alternatively in 54 patients with isolated mitral valve disease. No difference in functional improvement in the two groups was noted. Haemodynamic studies indicated a striking decrease in left atrial and pulmonary artery pressure, irrespective of the type of prosthesis inserted. Cardiac output incresed after operation, but was significantly different from the pre-operative value only in patients with the Björk-Shiley prosthesis, which also had a more favourable relationship between cardiac output and oxygen uptake during excercise than the Lillehei-Kaster prosthesis...
1977: Scandinavian Journal of Thoracic and Cardiovascular Surgery
K Haerten, A Both, J Lück, J Herzer, F Loogen
After mitral valve replacement hemodynamic abnormalities persist. These abnormalities were studied 1 year postoperatively. In 50 randomized patients; 15 with Starr-Edwards (SEM), 15 with Lillehei-Kaster (LKM) and 20 with Björk-Shiley (BSM) prostheses at rest and during exercise. Simultaneously were determined: pulmonary arterial pressure, left atrial pressure, left ventricular enddiastolic pressure, mean diastolic pressure gradient across the prostheses, cardiac index, stroke volume index, valve orifice area, and ejection fraction...
May 1977: Zeitschrift Für Kardiologie
E Sauer, H Sebening, L Lutilsky, H Dressler, G Hör, H W Pabst, H Blömer
ECG-gated cardiac blood pool scintigraphy permits a non-invasive determination of the end-diastolic and end-systolic ventricular volumes and of the ejection fraction as well as a qualitative description of regional ventricular wall motion at rest and during excercise. In 6 healthy persons a significant increase of the ejection fraction from 66 +/- 7% at rest to 78 +/- 3% during exercise (p less than 0.01) was observed. In contrast, the ejection fraction decreased in 15 out of 18 patients with coronary artery disease, with a significant (p less than 0...
October 1978: Nuklearmedizin. Nuclear Medicine
K Motyka, S Kozłowski
Seven young, male subjects were tested before and immediately after 6 weeks high-mountain expedition. Cardio-respiratory measurements were performed at rest and during standard physical excercise (10 min, 100 W) when breathing atmospheric air or hypoxic mixture (14% O2 in N2). After the expedition an increased V o2 max (16% an average) and diminished heart rate response to submaximal exercise were found. This was observed during air and hypoxic mixture breathing. There was significant increase in stroke volume and cardiac output during the exercise...
March 1979: Acta Physiologica Polonica
A W Langer, P A Obrist, J A McCubbin
The purpose of this study was to examine whether the hemodynamic and metabolic consequences of a physical (treadmill excercise) and behavioral (signaled shock-avoidance) stressor could be differentiated. To do this, direct continuous recordings of cardiac output, systolic and diastolic blood pressure, and discrete determinations of the arterial-mixed venous oxygen ((a-v)O2) content difference were analyzed in six dogs during exposure to three grades of treadmill exercise and when working on a shock-avoidance task...
February 1979: American Journal of Physiology
G Koch
The effect of 3'-chloro-2'-[N-methyl-N[(morpholino-carbonyl)methyl]aminomethyl]benzanilide-hydrochloride (forminoben-HCl, Noleptan) on pulse rates and blood pressures, ventilation and gas exchange, and acid base balance was studied in eleven patients aged 31 to 72 years at rest and during a standardised excercise. Mean systolic and diastolic blood pressures decreased at rest before and 10 min after work as well as during work. Mean alveolar ventilation was reduced by 9% at rest and was unchanged during work...
1976: Arzneimittel-Forschung
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