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https://www.readbyqxmd.com/read/29165431/spinal-accessory-nerve-preservation-in-modified-neck-dissections-surgical-and-functional-outcomes
#1
V Popovski, A Benedetti, D Popovic-Monevska, A Grcev, A Stamatoski, J Zhivadinovik
The spinal accessory nerve (SAN) or XI cranial nerve is frequently encountered during neck surgery, and as such is at risk of iatrogenic injury, resulting in "shoulder syndrome". Modified neck dissection (MND) with preservation of the SAN is based on desire to minimise the functional deformity associated with section of the eleventh nerve. The aim of this study was to analyse the intra-operative variations of the spinal accessory nerve pathway and to evaluate shoulder dysfunction postoperatively. The cross-sectional demonstration analysis was created through the medical records retrospectively of 165 consecutive patients who underwent neck dissections at our institution in the past 5 years with attention to ultrasound and MRI preoperative findings, type of neck dissection, type of identification and dissection of SAN, postoperative morbidity and survival rate...
October 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29160774/etchant-free-transfer-of-2d-nanostructures
#2
Fu Zhang, Chad Erb, Lauren Runkle, Xiaotian Zhang, Nasim Alem
The effective use of the van der Waals 2D materials relies on their successful transfer from the growth substrate onto other target substrates in the form of large films or flakes. In particular, it is important to transfer such atomically thin samples to various substrates with minimal sample damage and exposure to etchants and chemicals to realize their applications. Here we develop a universal transfer method that not only is free of reactive etchants, but also can maintain the film morphology intact with no tears and cracks...
November 21, 2017: Nanotechnology
https://www.readbyqxmd.com/read/29153108/evaluation-of-a-semi-automated-computer-algorithm-for-measuring-total-fat-and-visceral-fat-content-in-lambs-undergoing-in-vivo-whole-body-computed-tomography
#3
Alana J Rosenblatt, Peter V Scrivani, Yves R Boisclair, Anthony P Reeves, Jose M Ramos-Nieves, Yiting Xie, Hollis N Erb
Computed tomography (CT) is a suitable tool for measuring body fat, since it is non-destructive and can be used to differentiate metabolically active visceral fat from total body fat. Whole body analysis of body fat is likely to be more accurate than single CT slice estimates of body fat. The aim of this study was to assess the agreement between semi-automated computer analysis of whole body volumetric CT data and conventional proximate (chemical) analysis of body fat in lambs. Data were collected prospectively from 12 lambs that underwent duplicate whole body CT, followed by slaughter and carcass analysis by dissection and chemical analysis...
October 2017: Veterinary Journal
https://www.readbyqxmd.com/read/29148032/secondary-glaucoma-in-uveitis-comparison-of-the-optic-nerve-head-morphology-among-a-nonmydriatic-fundus-camera-hrt-and-sd-oct
#4
Milena Pahlitzsch, Matthias K J Klamann, Saskia Jacob, Carl Erb, Sibylle Winterhalter, Necip Torun, Anna-Karina B Maier, Eckart Bertelmann
PURPOSE: To assess the correlation between the disc damage likelihood scale (DDLS) objectively measured by a nonmydriatic fundus camera, confocal laser scanning ophthalmoscopy (HRT3), and spectral-domain optical coherence tomography (SD-OCT) in uveitic glaucoma. METHODS: A total of 59 patients with uveitic glaucoma (21 female, 38 male; mean age 56.8 ± 18.7 years) were included in this prospective cross-sectional study. All patients were measured by the Kowa Nonmyd WX 3D camera (2D/3D nonmydriatic retinal camera, Kowa Company), the HRT3 (Heidelberg Engineering), and SD-OCT (Carl Zeiss Meditec) by one examiner on the same day...
November 4, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29146616/therapeutic-potential-of-afatinib-for-cancers-with-erbb2-her2-transmembrane-domain-mutations-g660d-and-v659e
#5
Hiromasa Yamamoto, Shinichi Toyooka, Takashi Ninomiya, Shigemi Matsumoto, Masashi Kanai, Shuta Tomida, Katsuyuki Kiura, Manabu Muto, Ken Suzawa, Patrice Desmeules, Mark G Kris, Bob T Li, Marc Ladanyi
We previously reported on a family with hereditary lung cancer, in which a germline mutation in the transmembrane domain (G660D) of avian erythroblastic leukemia viral oncogene homolog 2 (erb-b2 receptor tyrosine kinase 2) (ERBB2; human epidermal growth factor receptor 2 [HER2]) seemed to be responsible for the cancer predisposition. Although few data are available on treatment, anti-ERBB2 therapeutic agents may be effective for ERBB2-mutant cancers. The familial lung cancer patient in one of the authors' institutes developed bone metastasis with enlarging lung tumors and was treated with the ERBB2 inhibitor afatinib...
November 16, 2017: Oncologist
https://www.readbyqxmd.com/read/29138387/strategies-for-feeding-the-world-more-sustainably-with-organic-agriculture
#6
Adrian Muller, Christian Schader, Nadia El-Hage Scialabba, Judith Brüggemann, Anne Isensee, Karl-Heinz Erb, Pete Smith, Peter Klocke, Florian Leiber, Matthias Stolze, Urs Niggli
Organic agriculture is proposed as a promising approach to achieving sustainable food systems, but its feasibility is also contested. We use a food systems model that addresses agronomic characteristics of organic agriculture to analyze the role that organic agriculture could play in sustainable food systems. Here we show that a 100% conversion to organic agriculture needs more land than conventional agriculture but reduces N-surplus and pesticide use. However, in combination with reductions of food wastage and food-competing feed from arable land, with correspondingly reduced production and consumption of animal products, land use under organic agriculture remains below the reference scenario...
November 14, 2017: Nature Communications
https://www.readbyqxmd.com/read/29138006/distorted-leukocyte-migration-angiogenesis-wound-repair-and-metastasis-in-tspan8-and-tspan8-cd151-double-knockout-mice-indicate-complementary-activities-of-tspan8-and-cd51
#7
Kun Zhao, Ulrike Erb, Thilo Hackert, Margot Zöller, Shijing Yue
No abstract text is available yet for this article.
November 11, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29119226/-current-developments-in-minimally-invasive-glaucoma-surgery
#8
EDITORIAL
C Erb
No abstract text is available yet for this article.
November 8, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29117383/assisted-reproductive-technology-in-europe-2013-results-generated-from-european-registers-by-eshre
#9
C Calhaz-Jorge, C De Geyter, M S Kupka, J de Mouzon, K Erb, E Mocanu, T Motrenko, G Scaravelli, C Wyns, V Goossens
STUDY QUESTION: Are there any changes in the treatments involving ART and IUI initiated in Europe during 2013 compared with previous years? SUMMARY ANSWER: An increase in the overall number of ART cycles resulting from a higher number of countries reporting data was evident, the pregnancy rates (PRs) in 2013 remained stable compared with those reported in 2012, the number of transfers with multiple embryos (3+) was lower than ever before yet the multiple delivery rates (DRs) remained unchanged, and IUI activity and success rates were similar to those of last years...
October 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29110122/-suprachoroidal-minimally-invasive-glaucoma-surgery-procedures-and-clinical-outcome
#10
REVIEW
C Erb
The uveoscleral outflow route is via the ciliary muscles into the suprachoroidal spaces and then to the orbital blood and lymph systems. The main driving force behind this uveoscleral outflow is the high oncotic pressure in the choroidal vessels. Currently, the CyPass microstent is the only available suprachoroidal device for ab interno minimally invasive glaucoma surgery. The CyPass achieves a maximum reduction of intraocular pressure (IOP) to 16-17 mm Hg over 12-24 months and is approved for mild to moderate primary open-angle glaucoma...
November 6, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29109006/the-rs2292239-polymorphism-in-erbb3-gene-is-associated-with-risk-for-type-1-diabetes-mellitus-in-a-brazilian-population
#11
Natália Emerim Lemos, Cristine Dieter, Luiza Emy Dorfman, Taís Silveira Assmann, Guilherme Coutinho Kullmann Duarte, Luis Henrique Canani, Andrea Carla Bauer, Daisy Crispim
The Erb-b2 receptor tyrosine kinase 3 (ERBB3) belongs to a family of epidermal growth factor receptors of protein tyrosine kinases, and regulates cell survival, differentiation and proliferation in several cell types. Previous studies have suggested that ERBB3 contributes to T1DM pathogenesis by modulating antigen presenting cell function, autoimmunity and cytokine-induced beta-cell apoptosis. Accordingly, some genome-wide association studies identified ERBB3 gene as a susceptibility locus for T1DM, with the strongest association signal being observed for the rs2292239 single nucleotide polymorphism (SNP) in intron 7 of the gene...
November 3, 2017: Gene
https://www.readbyqxmd.com/read/29104616/consumption-based-conservation-targeting-linking-biodiversity-loss-to-upstream-demand-through-a-global-wildlife-footprint
#12
Justin Kitzes, Eric Berlow, Erin Conlisk, Karlheinz Erb, Katsunori Iha, Neo Martinez, Erica A Newman, Christoph Plutzar, Adam B Smith, John Harte
Although most conservation efforts address the direct, local causes of biodiversity loss, effective long-term conservation will require complementary efforts to reduce the upstream economic pressures, such as demands for food and forest products, which ultimately drive these downstream losses. Here, we present a wildlife footprint analysis that links global losses of wild birds to consumer purchases across 57 economic sectors in 129 regions. The United States, India, China, and Brazil have the largest regional wildlife footprints, while per-person footprints are highest in Mongolia, Australia, Botswana, and the United Arab Emirates...
September 2017: Conservation Letters
https://www.readbyqxmd.com/read/29068771/investigation-of-a-worker-death-while-agitating-manure-in-a-non-enclosed-storage
#13
John M Shutske, Daniel Schaefer, Rebecca Larson, Kevin Erb, Cheryl Skjolaas, Stephanie Leonard, Jeff Nelson, Elizabeth Binversie, Scott Rifleman
An in-depth investigation of an unusual, non-enclosed manure storage hydrogen sulfide fatality on a Holstein beef production operation is presented. The case involved several factors that likely played a role in the young farmer's death. These included zero wind movement, a reported temperature inversion in the area, relatively cool late summer outdoor temperatures on the morning of the incident, higher outdoor temperatures the week prior, and a high by-product steer ration containing ingredients that contributed significant sulfur content to the stored manure...
October 25, 2017: Journal of Agromedicine
https://www.readbyqxmd.com/read/29068059/recent-progress-of-retroauricular-robotic-thyroidectomy-with-the-new-surgical-robotic-system
#14
Hyung Kwon Byeon, F Christopher Holsinger, Umamaheswar Duvvuri, Da Hee Kim, Jae Hong Park, Estelle Chang, Se-Heon Kim, Yoon Woo Koh
OBJECTIVE: Previously, we have reported the feasibility of retroauricular (RA) robotic thyroidectomy. Despite its promising surgical outcomes, there were certain intrinsic mechanical limitations inherent to the da Vinci Si System (Intuitive Surgical, Sunnyvale, California, U.S.A.). Since the advent of an upgraded model, the Xi System (Intuitive Surgical), we have actively incorporated the new model into performing RA thyroidectomy. Here, we intend to verify the feasibility of RA robotic thyroidectomy using the new da Vinci Xi System (Intuitive Surgical) with comparison of the former Si-applied surgery (Intuitive Surgical)...
October 25, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29048672/de-novo-synthesis-of-c4-4a-in-hepatocellular-carcinoma-promotes-migration-and-invasion-of-tumor-cells
#15
Magdalena Görtz, Uwe Galli, Thomas Longerich, Margot Zöller, Ulrike Erb, Peter Schemmer
C4.4A is a glycoprotein that is upregulated in several human malignancies, including colorectal, breast and renal cell carcinomas. Due to its highly restricted expression in healthy tissue, C4.4A was proposed as a potential diagnostic marker. Thus, the present study was designed to evaluate C4.4A expression and function in hepatocellular carcinoma (HCC) for the first time. Immunohistochemistry was performed to detect expression of C4.4A in human sections of healthy liver, primary HCC in the liver and metastatic HCC in the lung...
September 20, 2017: Oncology Reports
https://www.readbyqxmd.com/read/29044128/effects-of-vessel-traffic-and-underwater-noise-on-the-movement-behaviour-and-vocalisations-of-bottlenose-dolphins-in-an-urbanised-estuary
#16
Sarah A Marley, Chandra P Salgado Kent, Christine Erbe, Iain M Parnum
The potential disturbance of dolphins from tourism boats has been widely discussed in the literature, in terms of both physical vessel presence and associated underwater noise. However, less attention has been paid to the potential impact of non-tourism vessels, despite these being much more widespread and occurring in greater numbers throughout coastal dolphin habitats. The Indo-Pacific bottlenose dolphin (T. aduncus) community using the Fremantle Inner Harbour, Western Australia, is exposed to high levels of vessel traffic...
October 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29037469/management-of-patients-with-adenocarcinoma-or-squamous-cancer-of-the-esophagus
#17
David H Ilson, Richard Hillegersberg
Esophageal cancer is characterized by the early and frequent metastasis. Surgery is the primary treatment for early-stage disease, whereas patients with patients with locally advanced disease receive peri-operative chemotherapy or chemoradiotherapy. Squamous cancers can be treated with primary chemoradiotherapy without surgery, depending on their response to therapy and patient tolerance for subsequent surgery. Chemotherapy with a fluorinated pyrimidine and a platinum agent, followed by later treatment with taxanes and irinotecan, provides some benefit...
October 13, 2017: Gastroenterology
https://www.readbyqxmd.com/read/29019571/prognostic-factors-and-overall-survival-of-breast-cancer-in-the-city-of-goiania-brazil-a-population-based-study
#18
Ruffo de Freitas, Rodrigo Disconzi Nunes, Edesio Martins, Maria Paula Curado, Nilceana Maya Aires Freitas, Leonardo Ribeiro Soares, José Carlos Oliveira
OBJECTIVE: to analyze the overall survival and prognostic factors of women with breast cancer in the city of Goiânia. METHODS: this is a retrospective, cross-sectional, observational study that included women with malignant neoplasms of the breast identified by the Goiânia Population-based Cancer Registry. The variables studied were age at diagnosis, tumor size, staging, axillary lymph node involvement, tumor grade, disease extent, hormone receptors, and c-erb-B2 oncoprotein...
September 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28990415/redox-regulation-of-heme-oxygenase-2-and-the-transcription-factor-rev-erb-through-heme-regulatory-motifs
#19
Angela S Fleischhacker, Eric L Carter, Stephen W Ragsdale
SIGNIFICANCE: Heme binds to and serves as a cofactor for a myriad of proteins that are involved in diverse biological processes. Hemoproteins also exhibit varying modes of heme binding, suggesting that the protein environment contributes to the functional versatility of this prosthetic group. The subject of this review is a subset of hemoproteins that contain at least one heme regulatory motif (HRM), which is a short sequence containing a Cys-Pro core that, in many cases, binds heme with the Cys acting as an axial ligand...
November 14, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28981613/-wrong-way-up-temporal-and-spatial-dynamics-of-the-networks-for-body-motion-processing-at-9-4-t
#20
Marina A Pavlova, Michael Erb, Gisela E Hagberg, Joana Loureiro, Alexander N Sokolov, Klaus Scheffler
Body motion delivers a wealth of socially relevant information. Yet display inversion severely impedes biological motion (BM) processing. It is largely unknown how the brain circuits for BM are affected by display inversion. As upright and upside-down point-light BM displays are similar, we addressed this issue by using ultrahigh field functional MRI at 9.4 T providing for high sensitivity and spatial resolution. Whole-brain analysis along with exploration of the temporal dynamics of the blood-oxygen-level-dependent response reveals that in the left hemisphere, inverted BM activates anterior networks likely engaged in decision making and cognitive control, whereas readily recognizable upright BM activates posterior areas solely...
July 10, 2017: Cerebral Cortex
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