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https://www.readbyqxmd.com/read/28492049/a-review-of-laser-and-light-therapy-in-melasma
#1
REVIEW
M K Trivedi, F C Yang, B K Cho
Melasma is a dysregulation of the homeostatic mechanisms that control skin pigmentation and excess pigment is produced. Traditional treatment approaches with topical medications and chemical peels are commonly used but due to the refractory and recurrent nature of melasma, patients often seek alternative treatment strategies such as laser and light therapy. Several types of laser and light therapy have been studied in the treatment of melasma. Intense pulsed light, low fluence Q-switched lasers, and non-ablative fractionated lasers are the most common lasers and light treatments that are currently performed...
March 2017: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/28349023/fractional-carbon-dioxide-laser-and-its-combination-with-subcision-in-improving-atrophic-acne-scars
#2
Mohammad Ali Nilforoushzadeh, Gita Faghihi, Fariba Jaffary, Elaheh Haftbaradaran, Sayed Mohsen Hoseini, Nafiseh Mazaheri
BACKGROUND: Acne is a very common skin disease in which scars are seen in 95% of the patients. Although numerous treatments have been recommended, researchers are still searching for a single modality to treat the complication due to its variety in shape and depth. We compared the effects of fractional carbon dioxide (CO2) laser alone and in combination with subcision in the treatment of atrophic acne scars. MATERIALS AND METHODS: This clinical trial study was performed in Skin Diseases and Leishmaniasis Research Center (Isfahan, Iran) during 2011-2012...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28328709/the-clinical-and-histological-effect-of-a-low-fluence-q-switched-1-064-nm-neodymium-yttrium-aluminum-garnet-laser-for-the-treatment-of-melasma-and-solar-lentigo-in-asians-prospective-randomized-and-split-face-comparative-study
#3
Chikako Kaminaka, Fukumi Furukawa, Yuki Yamamoto
BACKGROUND: The low-fluence Q-switched 1,064-nm neodymium:yttrium-aluminum-garnet laser (QSNYL) is popular for melasma treatment among Asians. OBJECTIVE: This study was to evaluate the clinical and histological effects of the low-fluence QSNYL for treatment of melasma and solar lentigo. MATERIALS AND METHODS: In this randomized split-face clinical study, 22 patients with melasma or solar lentigo received low-fluence QSNYL weekly for 10 sessions on one cheek...
March 21, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28274355/topical-treatments-for-acne
#4
Marita Kosmadaki, Andreas Katsambas
Topical drugs have been used successfully to treat acne for decades. This review discusses the use, efficacy, and safety of options available via prescription. Topical antibiotics, dapsone, benzyl peroxide, azelaic acid, and topical retinoids are included. Topical antibiotics should not be used as monotherapy but rather be combined with other agents to avoid resistant Propionibacterium acnes strains. Benzoyl peroxide is effective in preventing bacteria resistance. Topical retinoids address primarily the comedonal but also the inflammatory lesions of acne...
March 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28216035/sun-protective-behaviors-in-patients-with-cutaneous-hyperpigmentation-a-cross-sectional-study
#5
Mayra B C Maymone, Hind H Neamah, Stephen A Wirya, Nicole M Patzelt, Pedro Q Zancanaro, Neelam A Vashi
BACKGROUND: Disorders of hyperpigmentation are seen commonly in clinical practice. Despite numerous studies investigating sun-protective habits among healthy persons, little is known about these behaviors within patient populations with hyperpigmentation disorders. OBJECTIVE: We sought to examine photo-protective behaviors and their associations in individuals with disorders of hyperpigmentation. METHODS: This cross-sectional study was conducted with 404 adults who complained of cutaneous hyperpigmentation...
May 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28114204/treatment-of-postinflammatory-hyperpigmentation-with-a-combination-of-glycolic-acid-peels-and-a-topical-regimen-in-dark-skinned-patients-a-comparative-study
#6
RANDOMIZED CONTROLLED TRIAL
Rashmi Sarkar, Nisha V Parmar, Sheilly Kapoor
BACKGROUND: Facial postinflammatory hyperpigmentation (PIH) is challenging to manage in patients with skin of color because of the risk of subsequent treatment-related hyperpigmentation. OBJECTIVE: To evaluate the safety and efficacy of combining glycolic acid (GA) peels with a modified Kligman formula (MKF) containing hydroquinone 2%, tretinoin 0.05%, and hydrocortisone 1% for the treatment of facial PIH in Indian patients. METHODS: Thirty Indian patients (Fitzpatrick skin Types III-V) with facial PIH were randomly assigned to 2 groups of 15 each...
April 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27976510/evaluation-of-salicylic-acid-peeling-in-comparison-with-topical-tretinoin-in-the-treatment-of-postinflammatory-hyperpigmentation
#7
Basma Morad Mohamed Ali, Shereen Farouk Gheida, Nageh Ahmed El Mahdy, Shery Nashaat Sadek
BACKGROUND: Postinflammatory hyperpigmentation (PIH) is an acquired hyperpigmentation that involves areas of prior cutaneous inflammation. In addition to prevention, there are a variety of medications and procedures used to treat PIH. AIM OF THE WORK: The aim of this work was to evaluate the efficacy, tolerability, and safety of salicylic acid peeling in comparison with topical tretinoin in the treatment of PIH. PATIENTS AND METHODS: This study included forty-five patients with PIH lesions...
December 15, 2016: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27973642/laser-treatments-for-postinflammatory-hyperpigmentation-a-systematic-review
#8
Oma Agbai, Iltefat Hamzavi, Jared Jagdeo
Importance: Lasers are gaining interest as a treatment option for postinflammatory hyperpigmentation (PIH) but can pose a clinical dilemma given the risk for laser-induced or exacerbated PIH. Objective: To assess the clinical evidence for the use of lasers in the treatment of PIH. Evidence Review: A systematic review was performed by searching PubMed databases from January 1, 1990, through May 31, 2016. Included studies involved laser treatment for PIH with the degree of pigmentation as a measure of outcome...
December 14, 2016: JAMA Dermatology
https://www.readbyqxmd.com/read/27918005/a-review-of-melasma-treatment-focusing-on-laser-and-light-devices
#9
REVIEW
Janet Y Li, Elizabeth Rc Geddes, Deanne M Robinson, Paul M Friedman
Melasma is a pigmentary disorder of unclear etiology with numerous treatment options and high recurrence rates. Laser and light therapies may be utilized cautiously as second- or third-line options for recalcitrant melasma, but low-energy settings are preferred due to the risk of postinflammatory hyperpigmentation and melasma stimulation. Commonly used lasers include the low-fluence 1064-nm Q-switched neodymium-doped yttrium aluminum garnet laser, nonablative fractionated lasers, and intense pulsed light. Strict sun protection, concomitant use of bleaching agents, and maintenance treatments are necessary...
December 2016: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/27918004/what-devices-to-use-or-not-use-in-skin-of-color
#10
Murad Alam
Lasers and light sources, as well as other energy devices, including radiofrequency, ultrasound, and cold-based therapies, can be used for treatment of aging, dyschromic, or texturally uneven skin. In patients with ethnic skin (ie, skin of color), energy devices are used more cautiously to avoid adverse events. The most common and concerning adverse event is postinflammatory hyperpigmentation. Lower fluence, longer pulse durations, and careful device selection can mitigate the risk of scarring and pigmentary abnormality...
December 2016: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/27900835/treatment-of-cutaneous-larva-migrans-with-a-single-session-of-carbon-dioxide-laser-a-study-of-ten-cases-in-the-philippines
#11
Livia Francine Soriano, Miriam Emily Piansay-Soriano
BACKGROUND: Cutaneous larva migrans (CLM) has a detrimental effect on patients' emotional and physical quality of life. Due to local unavailability of gold standard oral treatments for CLM, carbon dioxide laser was attempted. We present a case series where a single session of carbon dioxide laser treatment was associated with cessation of signs and symptoms of CLM. AIMS: The aim of this study was to assess the efficacy of a single session of carbon dioxide laser in the treatment of CLM...
March 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27786580/postinflammatory-hyperpigmentation-associated-with-treatment-of-solar-lentigines-using-a-q-switched-532-nm-nd-yag-laser-a-multicenter-survey
#12
Hyun Ji Kang, Jung Im Na, Jong Hee Lee, Mi Ryung Roh, Joo Yeon Ko, Sung Eun Chang
PURPOSE: To characterize the risk factors of Korean patients for postinflammatory hyperpigmentation (PIH) during treatment of solar lentigines using a Q-switched 532-nm Nd: YAG (QS 532 NY) laser. MATERIALS AND METHODS: The present retrospective multicenter study was conducted at the dermatology clinics of five tertiary hospitals in Korea. Between October 2007 and January 2013, 516 patients were enrolled and reviewed for clinical features and factors associated with PIH...
November 15, 2016: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/27770491/an-efficacy-and-safety-of-nanofractional-radiofrequency-for-the-treatment-of-striae-alba
#13
Napatthaorn Pongsrihadulchai, Thep Chalermchai, Suwirakorn Ophaswongse, Suriya Pongsawat, Montree Udompataikul
BACKGROUND: Striae distensae (SD) is a form of dermal scar. A number of treatments have been proposed, but they usually have unsatisfactory result especially in striae alba. Recently, nanofractional RF has been developed. Its mechanism of action is to stimulate dermal remodeling and epidermal re-epithelization. AIM: To evaluate the efficacy and safety of nanofractional RF in the treatment of striae alba. PATIENTS/METHODS: This is an experimental, assessor-blinded, before-after study...
March 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27766668/two-histopathological-patterns-of-postinflammatory-hyperpigmentation-epidermal-and-dermal
#14
Ji-Youn Park, Ji-Hye Park, Sang Jin Kim, Ji Eun Kwon, Hee Young Kang, Eun-So Lee, You Chan Kim
BACKGROUND: Postinflammatory hyperpigmentation (PIH) commonly occurs, but the histopathological features are not well characterized. METHODS: A total of 21 PIH patients' medical charts were reviewed. Punch biopsies from lesional and perilesional normal skin were performed. Sections were stained with hematoxylin-eosin, Fontana-Masson, NKI/beteb, microphthalmia-associated transcription factor (MITF), CD68, c-kit, factor XIIIa, MMP-2 and MMP-9. RESULTS: Fontana-Masson-stained sections suggested two obvious PIH groups: epidermal (13 cases) and dermal (8 cases) pigmentation...
February 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/27762482/treatment-of-erythematotelangiectatic-rosacea-with-the-fractionation-of-high-fluence-long-pulsed-595-nm-pulsed-dye-laser
#15
Jin Ok Baek, Hoon Hur, Ha Ryeong Ryu, Jeong Soo Kim, Kyung Real Lee, Yu Ri Kim, Kwang Ho Choi
Various lasers have been used for the treatment of erythematotelangiectatic rosacea (ETR) that does not respond to systemic or topical therapy. The pulsed dye lasers (PDLs) are an effective option for ETR, and the purpuragenic fluence proved to be superior until now. Given that purpura and subsequent possible postinflammatory hyperpigmentation (PIH) are occasionally unbearable in some patients, and several studies using the low nonpurpuragenic fluence were reported. To deliver the sufficient high fluence of a PDL without generating purpura, we designed the fractionation of high fluence using five passes and longer pulse duration (6 milliseconds) of a PDL in succession...
October 20, 2016: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27755171/microneedling-a-comprehensive-review
#16
Angela Hou, Brandon Cohen, Adele Haimovic, Nada Elbuluk
BACKGROUND: Microneedling is a minimally invasive procedure that uses fine needles to puncture the epidermis. The microwounds created stimulate the release of growth factors and induce collagen production. The epidermis remains relatively intact, therefore helping to limit adverse events. The indications for microneedling therapy have grown significantly, and it is becoming a more widely used treatment in dermatology. OBJECTIVE: A comprehensive review of microneedling in human subjects and its applications in dermatology...
March 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27743393/adjuvant-alternative-treatment-with-chemical-peeling-and-subsequent-iontophoresis-for-postinflammatory-hyperpigmentation-erosion-with-inflamed-red-papules-and-non-inflamed-atrophic-scars-in-acne-vulgaris
#17
Ichiro Kurokawa, Naoki Oiso, Akira Kawada
The standard management of acne vulgaris in Japan includes a combination of topical treatment with benzoyl peroxide (BPO) and BPO/clindamycin (CLDM), topical adapalene and systemic antimicrobials. However, the treatment of therapy-resistant complications such as postinflammatory hyperpigmentation (PIH), erosions with inflamed red papules and atrophic scars has not been established. We performed chemical peeling with glycolic acid and iontophoresis with ascorbyl 2-phosphate 6-palmitate and DL-α-tocopherol phosphate for the treatment of PIH, erosions with inflamed red papules and non-inflamed atrophic scars in 31 patients with acne vulgaris (mild to severe severity), and evaluated the efficacy and safety of these interventions...
October 15, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27696509/inhibitory-effect-of-660-nm-led-on-melanin-synthesis-in-in%C3%A2-vitro-and-in%C3%A2-vivo
#18
Chang Taek Oh, Tae-Rin Kwon, Eun Ja Choi, Soon Re Kim, Joon Seok, Seog Kyun Mun, Kwang Ho Yoo, Yeon Shik Choi, Sun Young Choi, Beom Joon Kim
BACKGROUND: Skin hyperpigmentary disorders including postinflammatory hyperpigmentation, melasma, solar lentigines, and conditions like freckles are common. The light-emitting diodes (LEDs) are the latest category of nonthermal and noninvasive phototherapy to be considered in skin pigmentation disorder treatment. PURPOSE: The purpose of this study was to investigate the effects of 660-nm LED on inhibition of melanogenesis. We investigated whether a 660-nm LED affected melanin synthesis in in vitro and in vivo models, and we explored the mechanisms involved...
January 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/27688436/skin-hyperpigmentation-in-indian-population-insights-and-best-practice
#19
Stephanie Nouveau, Divya Agrawal, Malavika Kohli, Francoise Bernerd, Namita Misra, Chitra Shivanand Nayak
Skin pigmentation is one of the most strikingly variable phenotypes in humans, therefore making cutaneous pigmentation disorders frequent symptoms manifesting in a multitude of forms. The most common among them include lentigines, postinflammatory hyperpigmentation, dark eye circles, and melasma. Variability of skin tones throughout the world is well-documented, some skin tones being reported as more susceptible to pigmentation disorders than others, especially in Asia and India. Furthermore, exposure to ultraviolet radiation is known to trigger or exacerbate pigmentation disorders...
September 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27519176/dermal-remodeling-of-burn-scar-by-fractional-co2-laser
#20
Sang-Jun Lee, Dong-Hye Suh, Ji Min Lee, Kye-Yong Song, Hwa Jung Ryu
BACKGROUND: Ablative CO2 fractional lasers have recently been introduced for burn scar treatment because of pronounced clinical outcomes with fewer treatment sessions than nonablative fractional laser. OBJECTIVE: This study was conducted to observe clinical as well as histologic changes of burn scars after treatment with CO2 fractional laser. MATERIALS AND METHODS: Eleven patients (one female and 10 males, aged 31-59 years) with skin phototypes III to V with burn scars received 10 sessions of fractional CO2 laser treatments (UltraPulse(®) Encore; Lumenis, Santa Clara, CA, USA) over an average 5-week interval...
October 2016: Aesthetic Plastic Surgery
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