Jwan A Naser, Francisco B Alexandrino, Tomonari Harada, Hector I Michelena, Barry A Borlaug, Mackram F Eleid, Grace Lin, Christopher Scott, Austin M Kennedy, Patricia A Pellikka, Vuyisile T Nkomo, Sorin V Pislaru
BACKGROUND: The natural history of moderate/severe atrial functional mitral regurgitation (AFMR) is unknown. OBJECTIVES: The authors sought to study the incidence of left ventricular (LV) systolic dysfunction (LVSD), progression or regression of ≥mild-moderate AFMR, and impact on mortality. METHODS: Adults with left atrial (LA) volume index ≥40 mL/m2 , ≥mild-moderate AFMR, and follow-up echocardiogram were followed for incident LVSD (ejection fraction <50% and ≥10% lower than baseline), progression of mild-moderate/moderate AFMR to severe, and persistent regression of AFMR to no/trivial...
March 17, 2024: Journal of the American College of Cardiology