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https://www.readbyqxmd.com/read/28725332/thyrotoxic-valvulopathy-case-report-and-review-of-the-literature
#1
Keniel Pierre, Sushee Gadde, Bassam Omar, G Mustafa Awan, Christopher Malozzi
We report a 42-year-old female who was admitted for abdominal pain, and also endorsed dyspnea, fatigue and chronic palpitations. Past medical history included asthma, patent ductus arteriosus repaired in childhood and ill-defined thyroid disease. Physical examination revealed blood pressure of 136/88 mm Hg and heart rate of 149 beats per minute. Cardiovascular exam revealed an irregularly irregular rhythm, and pulmonary exam revealed mild expiratory wheezing. Abdomen was tender. Electrocardiogram revealed atrial fibrillation with rapid ventricular response which responded to intravenous diltiazem...
June 2017: Cardiology Research
https://www.readbyqxmd.com/read/28724192/handheld-echocardiography-during-hospitalization-for-acute-myocardial-infarction
#2
Michael W Cullen, Jeffrey B Geske, Nandan S Anavekar, J Wells Askew, Bradley R Lewis, Jae K Oh
BACKGROUND: Handheld echocardiography (HHE) is concordant with standard transthoracic echocardiography (TTE) in a variety of settings but has not been thoroughly compared to traditional TTE in patients with acute myocardial infarction (AMI). HYPOTHESIS: Completed by experienced operators, HHE provides accurate diagnostic capabilities compared with standard TTE in AMI patients. METHODS: This study prospectively enrolled patients admitted to the coronary care unit with AMI...
July 19, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28720600/is-the-mechanism-of-re-expansion-pulmonary-oedema-in-a-heart-lung-interaction
#3
Candy Masego Mokotedi, Martin Balik
The mechanism of re-expansion pulmonary oedema (Re-PE) is unclear. There are multiple variables in play when evaluating the response to evacuation of pleural fluid. We present an educational case of a critically ill patient admitted for respiratory failure who was fully dependent on ventricular pacing set at a constant rate throughout the episode of Re-PE. The transthoracic echocardiography (TTE) showed an ejection fraction of 38%, moderate mitral regurgitation (MR), mildly dilated right ventricle and moderate pulmonary hypertension...
July 18, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28715068/severe-mitral-regurgitation-is-associated-with-increased-copeptin-levels-in-heart-failure-with-reduced-ejection-fraction
#4
Alven Kılıcgedık, Elıf Eroglu, Gokhan Kahvecı, Khaganı Isgandarov, Emrah Acar, Semi Ozturk, Regayip Zehir, Seyhmus Kulahcıoglu, Cuneyt Toprak, Ali Yaman, Ibrahım Akın Izgı, Cevat Kirma
BACKGROUND AND AIM: The objective of this study was to assess the potential role of mitral regurgitation (MR) in the release of copeptin in HF patients with reduced ejection fraction (HFREF). METHODS: The study included 63 patients of whom 33 had functional mild MR (Group 1) and 30 had functional severe MR (Group 2).The functional classes of the groups were both NYHA Class III. Blood samples for the determination of plasma copeptin and B-type natriuretic peptide (BNP) levels were obtained at the same day with the echocardiographic examination...
July 17, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28712562/abnormal-right-atrial-performance-in-repaired-tetralogy-of-fallot-a-cmr-feature-tracking-analysis
#5
Shelby Kutty, Quanliang Shang, Navya Joseph, Johannes T Kowallick, Andreas Schuster, Michael Steinmetz, David A Danford, Phillip Beerbaum, Samir Sarikouch
BACKGROUND: We hypothesized that right atrial (RA) performance is abnormal in repaired tetralogy of Fallot (TOF). METHODS: TOF patients were prospectively enrolled for cardiovascular magnetic resonance (CMR), echocardiography and exercise stress following a standardized 14-center protocol. Peak RA longitudinal strain (RALS) and right ventricular longitudinal strain (RVLS) were measured using CMR feature tracking (FT) and correlated to RA and RV end diastolic volumes (EDVi) and ejection fraction (EF)...
July 8, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28712559/impact-of-percutaneous-mitral-valvuloplasty-on-left-ventricular-function-in-patients-with-mitral-stenosis-assessed-by-3d-echocardiography
#6
William Antonio M Esteves, Lucas Lodi-Junqueira, Juliana Rodrigues Soares, Guilherme Rafael Sant'Anna Athayde, Gabriela Assunção Goebel, Lucas Amorim Carvalho, Xin Zeng, Judy Hung, Timothy C Tan, Maria Carmo Pereira Nunes
BACKGROUND: The status of intrinsic left ventricular (LV) contractility in patients with isolated rheumatic mitral stenosis (MS) has been debated. The acute changes in loading conditions after percutaneous mitral valvuloplasty (PMV) may affect LV performance. We aimed to examine the acute effects of PMV on LV function and identify factors associated with LV ejection fraction (LVEF) changes, and determinants of long-term events following the procedure. METHODS: One hundred and forty-two patients who underwent PMV for symptomatic rheumatic MS (valve area of 0...
June 23, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28708196/assessment-of-mitral-apparatus-in-patients-with-acute-inferoposterior-myocardial-infarction-and-ischaemic-mitral-regurgitation-with-two-dimensional-echocardiography-from-anatomically-correct-imaging-planes
#7
Karolina Mėlinytė, Živile Valuckiene, Renaldas Jurkevičius
BACKGROUND: Ischaemic mitral regurgitation (IMR) is associated with adverse prognosis after myocardial infarction (MI) as a result of left ventricular remodelling and geometric deformation of the mitral apparatus (MA). AIM: The aim of this study was to assess MA from anatomically correct imaging planes in acute inferoposterior MI and IMR. METHODS: Ninety-three patients with no structural cardiac valve abnormalities and the first acute inferoposterior MI were prospectively enrolled into the study...
2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28706863/non-functional-tricuspid-valve-disease
#8
REVIEW
Dale S Adler
Only 75% of severe tricuspid regurgitation is classified as functional, or related primarily to pulmonary hypertension, right ventricular dysfunction, or a combination of both. Non-functional tricuspid regurgitation occurs when there is damage to the tricuspid leaflets, chordae, papillary muscles, or annulus, independent of right ventricular dysfunction or pulmonary hypertension. The entities that cause non-functional tricuspid regurgitation include rheumatic and myxomatous disease, acquired and genetic connective tissue disorders, endocarditis, sarcoid, pacing, RV biopsy, blunt trauma, radiation, carcinoid, ergot alkaloids, dopamine agonists, fenfluramine, cardiac tumors, atrial fibrillation, and congenital malformations...
May 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28706743/when-is-the-optimal-timing-of-surgical-intervention-for-severe-functional-tricuspid-regurgitation
#9
Nobuhiro Nakanishi, Masanobu Ishii, Koichi Kaikita, Ken Okamoto, Yasuhiro Izumiya, Eiichiro Yamamoto, Seiji Takashio, Seiji Hokimoto, Toshihiro Fukui, Kenichi Tsujita
Functional tricuspid regurgitation (TR) is a serious pathology to be noted for severe right heart failure (HF) and poor prognosis; however, the conventional assessment of TR has some limitations and the optimal timing of surgical intervention remains unclear. A 79-year-old Japanese female was admitted to our hospital to undergo cardiac surgery, because edema gradually got worse despite the increase in diuretics. She had a history of atrial fibrillation (AF) and chronic HF due to severe TR and had been treated with a furosemide for leg edema 4 years ago...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28705792/deletion-of-fstl1-follistatin-like-1-from-the-endocardial-endothelial-lineage-causes-mitral-valve-disease
#10
Stuti Prakash, Luis J J Borreguero, Marc Sylva, Lorena Flores Ruiz, Fereshte Rezai, Quinn D Gunst, José-Luis de la Pompa, Jan M Ruijter, Maurice J B van den Hoff
OBJECTIVE: Fstl1 (Follistatin-like 1) is a secreted protein that is expressed in the atrioventricular valves throughout embryonic development, postnatal maturation, and adulthood. In this study, we investigated the loss of Fstl1 in the endocardium/endothelium and their derived cells. APPROACH AND RESULTS: We conditionally ablated Fstl1 from the endocardial lineage using a transgenic Tie2-Cre mouse model. These mice showed a sustained Bmp and Tgfβ signaling after birth...
July 13, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/28705383/ischemic-or-nonischemic-functional-mitral-regurgitation-and-outcomes-in-patients-with-acute-decompensated-heart-failure-with-preserved-or-reduced-ejection-fraction
#11
Katsuya Kajimoto, Yuichiro Minami, Shigeru Otsubo, Naoki Sato
The aim of this study was to evaluate the association of functional mitral regurgitation (FMR), preserved or reduced ejection fraction (EF), and ischemic or nonischemic origin with outcomes in patients discharged alive after hospitalization for acute decompensated heart failure (HF). Of the 4,842 patients enrolled in the Acute Decompensated Heart Failure Syndromes (ATTEND) registry, 3,357 patients were evaluated to assess the association of FMR, preserved or reduced EF, and ischemic or nonischemic origin with the primary end point (all-cause death and readmission for HF after discharge)...
June 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28698259/reversibility-of-cardiac-function-predicts-outcome-after-transcatheter-aortic-valve-replacement-in-patients-with-severe-aortic-stenosis
#12
Kimi Sato, Arnav Kumar, Brandon M Jones, Stephanie L Mick, Amar Krishnaswamy, Richard A Grimm, Milind Y Desai, Brian P Griffin, L Leonardo Rodriguez, Samir R Kapadia, Nancy A Obuchowski, Zoran B Popović
BACKGROUND: Reversibility of left ventricular (LV) dysfunction in high-risk aortic stenosis patient and its impact on survival after transcatheter aortic valve replacement (TAVR) are unclear. We aimed to evaluate longitudinal changes of LV structure and function after TAVR and their impact on survival. METHODS AND RESULTS: We studied 209 patients with aortic stenosis who underwent TAVR from May 2006 to December 2012. Echocardiograms were used to calculate LV end-diastolic volume index (LVEDVi), LV ejection fraction, LV mass index (LVMi), and global longitudinal strain before, immediately (<10 days), late (1-3 months), and yearly after TAVR...
July 11, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28694396/assessment-of-subclinical-left-ventricular-systolic-function-using-strain-imaging-in-the-follow-up-of-patients-with-chronic-mitral-regurgitation
#13
Selen Yurdakul, Ali Doğan, Saide Aytekin
OBJECTIVE: Determining optimal timing for surgery in asymptomatic mitral regurgitation (MR) remains a challenge. The aim of this study was to evaluate subclinical changes in left ventricular (LV) systolic functions using velocity vector imaging (VVI) during follow-up of patients with chronic mitral regurgitation (MR). METHODS: A total of 54 patients (mean age: 57.9±8 years; 55% male) with moderate-to-severe MR and normal LV ejection fraction (EF), and 30 healthy controls (mean age: 56±6...
July 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28689751/postprocedural-changes-of-tricuspid-regurgitation-after-mitraclip-therapy-for-mitral-regurgitation
#14
Kentaro Toyama, Kengo Ayabe, Saibal Kar, Shunsuke Kubo, Toshinori Minamishima, Florian Rader, Takahiro Shiota, Toshihiko Nishioka, Robert J Siegel
The effect of percutaneous mitral valve repair using the MitraClip system on tricuspid regurgitation (TR) has not been well investigated. We retrospectively analyzed 102 consecutive patients who underwent the successful MitraClip procedure, and who also had a preprocedural and 1-year follow-up transthoracic echocardiography. TR severity was graded by standard guideline-recommended criteria. At 1 year after the MitraClip procedure, the degree of TR regressed (at least 1 grade) in 23% of the patients, was unchanged in 62% of the patients, and progressed in 16% of the patients...
June 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28684442/impact-of-the-left-ventricular-mass-index-on-the-outcomes-of-severe-aortic-stenosis
#15
Eri Minamino-Muta, Takao Kato, Takeshi Morimoto, Tomohiko Taniguchi, Moriaki Inoko, Tetsuya Haruna, Toshiaki Izumi, Shoichi Miyamoto, Eisaku Nakane, Kenichi Sasaki, Moritoshi Funasako, Koji Ueyama, Shinichi Shirai, Takeshi Kitai, Chisato Izumi, Kazuya Nagao, Tsukasa Inada, Eiji Tada, Akihiro Komasa, Katsuhisa Ishii, Naritatsu Saito, Ryuzo Sakata, Kenji Minatoya, Takeshi Kimura
OBJECTIVE: To elucidate the factors associated with high left ventricular mass index (LVMI) and to test the hypothesis that high LVMI is associated with worse outcome in severe aortic stenosis (AS). METHODS: We analysed 3282 patients with LVMI data in a retrospective multicentre registry enrolling consecutive patients with severe AS in Japan. The management strategy, conservative or initial aortic valve replacement (AVR), was decided by the attending physician. High LVMI was defined as LVMI >115 g/m(2) for males and >95 g/m(2) for females...
July 6, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28679970/clinical-significance-of-pulmonary-arterial-capacitance-calculated-by-echocardiography-in-patients-with-advanced-heart-failure
#16
Yuki Saito, Tomohito Ohtani, Hidetaka Kioka, Toshinari Onishi, Yasumasa Tsukamoto, Kei Nakamoto, Tatsunori Taniguchi, Satoshi Nakatani, Atsushi Hirayama, Yasushi Sakata
BACKGROUND: Advanced left heart failure (HF) often accompanies post-capillary pulmonary hypertension related to RV afterload. Although pulmonary arterial capacitance (PAC), a measure of pulmonary artery compliance, reflects right ventricular (RV) afterload, the clinical utility of PAC obtained by echocardiography (echo-PAC) is not well established in advanced HF.Methods and Results:We performed right heart catheterization in advanced HF patients (n=30), calculating echo-PAC as stroke volume/(tricuspid regurgitation pressure gradient-pulmonary regurgitation pressure gradient)...
July 4, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28676179/transaortic-edge-to-edge-mitral-valve-repair-for-moderate-secondary-functional-mitral-regurgitation-in-patients-undergoing-aortic-root-valve-intervention
#17
Shiv Kumar Choudhary, Atul Abraham, Amol Bhoje, Parag Gharde, Manoj Sahu, Sachin Talwar, Balram Airan
OBJECTIVE: The present study evaluates the feasibility, safety, and efficacy of edge-to-edge repair for moderate secondary/functional mitral regurgitation in patients undergoing aortic valve/root interventions. METHODS: Sixteen patients underwent transaortic edge-to-edge mitral valve repair. Mitral regurgitation was 2+ in 8 patients and 3+ in 6 patients. Two patients in whom cardiac arrest developed preoperatively had severe (4+) mitral regurgitation. Patients underwent operation for severe aortic regurgitation ± aortic root lesions...
June 13, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28668430/pixel-wise-derivation-of-pulmonary-regurgitation-index-could-influence-clinical-decision-a-phase-contrast-mr-imaging-study-on-patients-with-repaired-tetralogy-of-fallot
#18
Pei-Hsin Wu, Hsiao-Wen Chung, Ming-Ting Wu, Cheng-Wen Ko
PURPOSE: Regurgitant fraction (RF) measured from 2D phase-contrast MRI has been used as a standard to quantitate the degree of pulmonary regurgitation and serves as a determinant indicator of prognosis for tetralogy of Fallot after surgical repair. This study demonstrated the potential underestimate of RF using the conventional definition and its impact on clinical decision when backward flow occurred during systolic periods. METHODS: Quantitative flow parameters, including forward flow volume (FFV), backward flow volume (BFV), and RF were estimated by two approaches: One derived from conventional ROI-averaged curve (bulk quantity) and the other in a pixel-wise manner to spatially reflect inhomogeneous flow profile (pixel-wise quantity)...
August 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28655164/role-of-diastolic-function-indices-in-the-risk-stratification-of-patients-with-mixed-aortic-valve-disease
#19
Alexander C Egbe, Arooj R Khan, Amber Boler, Sameh M Said, Jeffrey B Geske, William R Miranda, Emmanuel Akintoye, Heidi M Connolly, Carole A Warnes, Jae K Oh
Aims: Determine the role of diastolic function indices in pre-operative and post-operative risk stratification in patients with moderate mixed aortic valve disease (MAVD). Methods and results: A retrospective study was conducted of asymptomatic patients with moderate MAVD (a combination of moderate aortic stenosis and moderate aortic regurgitation) and an ejection fraction of 50% or more who were followed up at Mayo Clinic from 1 January 2004, to 31 December 2013...
June 23, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28645469/transcatheter-mitral-valve-repair-with-mitraclip-for-symptomatic-functional-mitral-valve-regurgitation
#20
REVIEW
Rodrigo Mendirichaga, Vikas Singh, Vanessa Blumer, Manuel Rivera, Alex P Rodriguez, Mauricio G Cohen, William W O'Neill, Sammy Elmariah
Transcatheter edge-to-edge mitral valve repair (TMVr) with MitraClip has proved to be safe and effective for high-risk surgical patients with severe symptomatic degenerative mitral regurgitation. There is paucity of data regarding its use in functional mitral regurgitation (FMR). The objective of this study was to evaluate the use of MitraClip in patients with symptomatic moderate or severe FMR and a high surgical risk. Medical libraries were systematically searched for studies assessing the use of MitraClip for patients with symptomatic moderate or severe FMR and a high surgical risk...
May 30, 2017: American Journal of Cardiology
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