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Very low carbohydrate diet

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https://www.readbyqxmd.com/read/27922863/suppression-of-myocardial-18f-fdg-uptake-through-prolonged-high-fat-high-protein-and-very-low-carbohydrate-diet-before-fdg-pet-ct-for-evaluation-of-patients-with-suspected-cardiac-sarcoidosis
#1
Yang Lu, Christopher Grant, Karen Xie, Nadera J Sweiss
BACKGROUND: A major obstacle in using FDG-PET/CT to diagnose cardiac sarcoidosis (CS) is the unpredictable physiological myocardial FDG uptake. We hypothesized that a prolonged 72-hour pretest high-fat, high-protein, and very-low-carbohydrate (HFHPVLC) diet preparation could suppress physiologic myocardial uptake of FDG and thus help to identify active CS. METHODS: This retrospective study included 215 FDG-PET/CT tests from 207 patients with biopsy-proven sarcoidosis and clinical suspicion for CS between July 2014 and December 2015...
December 3, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27903745/inhibiting-microglia-expansion-prevents-diet-induced-hypothalamic-and-peripheral-inflammation
#2
Caroline André, Omar Guzman-Quevedo, Charlotte Rey, Julie Rémus-Borel, Samantha Clark, Ashley Castellanos-Jankiewicz, Elodie Ladeveze, Thierry Leste-Lasserre, Agnes Nadjar, Djoher Nora Abrous, Sophie Laye, Daniela Cota
Cell proliferation and neuroinflammation in the adult hypothalamus may contribute to the pathogenesis of obesity. Here we tested whether the intertwining of these two processes has a role in the metabolic changes caused by three weeks of saturated high-fat diet (HFD) consumption.As compared to chow, HFD-fed mice rapidly increased body weight and fat mass, and specifically showed increased microglia number in the arcuate nucleus (ARC) of the hypothalamus. Microglia expansion required the adequate presence of fats and carbohydrates in the diet, since feeding mice a very high-fat, very low-carbohydrate diet did not affect cell proliferation...
November 30, 2016: Diabetes
https://www.readbyqxmd.com/read/27903520/visceral-adiposity-and-metabolic-syndrome-after-very-high-fat-and-low-fat-isocaloric-diets-a-randomized-controlled-trial
#3
Vivian L Veum, Johnny Laupsa-Borge, Øyvin Eng, Espen Rostrup, Terje H Larsen, Jan Erik Nordrehaug, Ottar K Nygård, Jørn V Sagen, Oddrun A Gudbrandsen, Simon N Dankel, Gunnar Mellgren
BACKGROUND: Different aspects of dietary pattern, including macronutrient and food profiles, may affect visceral fat mass and metabolic syndrome. OBJECTIVE: We hypothesized that consuming energy primarily from carbohydrate or fat in diets with similar food profiles would differentially affect the ability to reverse visceral adiposity and metabolic syndrome. DESIGN: Forty-six men (aged 30-50 y) with body mass index (in kg/m(2)) >29 and waist circumference >98 cm were randomly assigned to a very high-fat, low-carbohydrate (VHFLC; 73% of energy fat and 10% of energy carbohydrate) or low-fat, high-carbohydrate (LFHC; 30% of energy fat and 53% of energy carbohydrate) diet for 12 wk...
November 30, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27891164/a-low-carbohydrate-high-fat-diet-decreases-lean-mass-and-impairs-cardiac-function-in-pair-fed-female-c57bl-6j-mice
#4
Jessica Nilsson, Madelene Ericsson, Masoumeh Motamedi Joibari, Fredrick Anderson, Leif Carlsson, Stefan K Nilsson, Anna Sjödin, Jonas Burén
BACKGROUND: Excess body fat is a major health issue and a risk factor for the development of numerous chronic diseases. Low-carbohydrate diets like the Atkins Diet are popular for rapid weight loss, but the long-term consequences remain the subject of debate. The Scandinavian low-carbohydrate high-fat (LCHF) diet, which has been popular in Scandinavian countries for about a decade, has very low carbohydrate content (~5 E %) but is rich in fat and includes a high proportion of saturated fatty acids...
2016: Nutrition & Metabolism
https://www.readbyqxmd.com/read/27876096/a-randomised-controlled-trial-of-the-effects-of-very-low-carbohydrate-and-high-carbohydrate-diets-on-cognitive-performance-in-patients-with-type-2-diabetes
#5
Jeannie Tay, Ian T Zajac, Campbell H Thompson, Natalie D Luscombe-Marsh, Vanessa Danthiir, Manny Noakes, Jonathan D Buckley, Gary A Wittert, Grant D Brinkworth
This study compared the longer-term effects of a very low-carbohydrate, high-fat diet with a high-carbohydrate, low-fat diet on cognitive performance in individuals with type 2 diabetes (T2D). In total, 115 obese adults with T2D (sixty-six males, BMI: 34·6 (sd 4·3) kg/m2, age: 58 (sd 7) years, HbA1c: 7·3 (sd 1·1) %, diabetes duration: 8 (sd 6) years) were randomised to consume either an energy-restricted, very low-carbohydrate, low-saturated-fat (LC) diet or an energy-matched high unrefined carbohydrate, low-fat (HC) diet with supervised aerobic/resistance exercise (60 min, 3 d/week) for 52 weeks...
November 23, 2016: British Journal of Nutrition
https://www.readbyqxmd.com/read/27875499/impact-of-acute-dietary-manipulations-on-dxa-and-bia-body-composition-estimates
#6
Grant M Tinsley, Flor E Morales, Jeffrey S Forsse, Peter W Grandjean
PURPOSE: To examine the effects of acute pre-assessment diets on body composition estimates obtained by dual-energy x-ray absorptiometry (DXA) and bioelectrical impedance analysis (BIA). METHODS: In a counterbalanced design, 48 males and females were provided with two one-day diets: high-carbohydrate diet (9 g CHO/kg) and very low-carbohydrate diet (1 to 1.5 g CHO/kg). For each condition, body composition was assessed in the morning after an overnight fast, in the afternoon after feeding, and the following morning after a second overnight fast...
November 21, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27826354/the-effects-on-weight-loss-and-gene-expression-in-adipose-and-hepatic-tissues-of-very-low-carbohydrate-and-low-fat-isoenergetic-diets-in-diet-induced-obese-mice
#7
Tomomi Yamazaki, Sumire Okawa, Mayumi Takahashi
BACKGROUND: Obesity is caused by excessive fat or carbohydrate intake. The improvement of obesity is an important issue, especially in Western societies. Both low-carbohydrate diet (LCD) and low-fat diet (LFD) are used to achieve weight loss in humans. To clarify the mechanisms underlying LCD-induced weight loss, especially in early stage, we compared the gene expression in liver, white adipose tissue (WAT) and brown adipose tissue (BAT) of a very-low carbohydrate diet (VLCD)- and LFD-fed diet-induced obese (DIO) mice...
2016: Nutrition & Metabolism
https://www.readbyqxmd.com/read/27822291/monitoring-for-compliance-with-a-ketogenic-diet-what-is-the-best-time-of-day-to-test-for-urinary-ketosis
#8
Paul Urbain, Hartmut Bertz
BACKGROUND: The ketogenic diet (KD) is a very low-carbohydrate, high-fat and adequate-protein diet with no calorie limit that induces a metabolic condition called "physiological ketosis". It was first introduced to treat epilepsy in the 1920s and has become quite popular recently as weight-loss and performance-enhancing diet. Its therapeutic use in a range of diseases is under investigation. During KD interventions people are supposed to monitor compliance with the dietary regimen by daily urine testing for ketosis...
2016: Nutrition & Metabolism
https://www.readbyqxmd.com/read/27756449/microalgae-as-a-safe-food-source-for-animals-nutritional-characteristics-of-the-acidophilic-microalga-coccomyxa-onubensis
#9
Francisco Navarro, Eduardo Forján, María Vázquez, Zaida Montero, Elisabeth Bermejo, Miguel Ángel Castaño, Alberto Toimil, Enrique Chagüaceda, Miguel Ángel García-Sevillano, Marisa Sánchez, María José Domínguez, Rosario Pásaro, Inés Garbayo, Carlos Vílchez, José María Vega
BACKGROUND: Edible microalgae are marine or fresh water mesophilic species. Although the harvesting of microalgae offers an abundance of opportunities to the food and pharmaceutical industries, the possibility to use extremophilic microalgae as a food source for animals is not well-documented. OBJECTIVE: We studied the effects of dietary supplementation of a powdered form of the acidophilic microalga Coccomyxa onubensis on growth and health parameters of laboratory rats...
2016: Food & Nutrition Research
https://www.readbyqxmd.com/read/27754766/the-effects-of-different-high-protein-low-carbohydrates-proprietary-foods-on-blood-sugar-in-healthy-subjects
#10
Alessandra Lodi, Bettina Karsten, Gerardo Bosco, Manuel Gómez-López, Paula Paraguassú Brandão, Antonino Bianco, Antonio Paoli
: The aim of this study was to analyze the effects on blood sugar concentrations through the calculation of the glycemic score (GS) of 10 different high-protein low-carbohydrates (CHOs) proprietary foods that are commonly used as meals during very low-CHO ketogenic diets or during low-CHO diets. Fourteen healthy females were tested for their glycemic response curve elicited by 1000 kJ of glucose three times within a 3-week period (one test each week) compared with one of 10 test foods once on separate days twice a week...
October 18, 2016: Journal of Medicinal Food
https://www.readbyqxmd.com/read/27733400/dietary-glycemic-index-glycemic-load-and-refined-carbohydrates-are-associated-with-risk-of-stroke-a-prospective-cohort-study-in-urban-chinese-women
#11
Danxia Yu, Xianglan Zhang, Xiao-Ou Shu, Hui Cai, Honglan Li, Ding Ding, Zhen Hong, Yong-Bing Xiang, Yu-Tang Gao, Wei Zheng, Gong Yang
BACKGROUND: Epidemiologic evidence on dietary carbohydrates and stroke risk remains controversial. Very few prospective cohort studies have been conducted in Asian populations, who usually consume a high-carbohydrate diet and have a high burden of stroke. OBJECTIVE: We examined dietary glycemic index (GI), glycemic load (GL), and intakes of refined and total carbohydrates in relation to risks of total, ischemic, and hemorrhagic stroke and stroke mortality. DESIGN: This study included 64,328 Chinese women, aged 40-70 y, with no history of cardiovascular disease, diabetes, or cancer...
November 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27723053/diet-e-ect-on-short-and-long-term-glycaemic-response-in-adult-healthy-cats
#12
Nadia Musco, Serena Calabro, Raffaella Tudisco, Micaela Grossi, Laura Addi, Giuseppe Moniello, Pietro Lombardi, Monica Isabella Cutrignelli
In the paper the short- and long-term glycaemic response after 4 diet programmes was evaluated. Each diet programme was alternatively administered to 6 healthy cats for 30 days. At the end of each period cats were weighed and underwent blood sampling for glucose and fructosamine determination. Glycaemia was measured every 2 hours for 24 hours using an automated glucometer. Very high protein level and low starch (VHP/LS) and high protein and moderate starch level (HP/LS) diets showed glucose (Mean and Peak) and fructosamine values signi cantly lower compared to the moderate protein and high starch diets (MP/HS)...
August 3, 2016: Veterinaria Italiana
https://www.readbyqxmd.com/read/27703476/diet-related-knowledge-and-physical-activity-in-a-large-cohort-of-insulin-treated-type-2-diabetes-patients-progens-arena-study
#13
Tomasz Klupa, Michał Możdżan, Janina Kokoszka-Paszkot, Magdalena Kubik, Małgorzata Masierek, Margerita Czerwińska, Maciej T Małecki
There is no doubt that behavioral intervention is crucial for type 2 diabetes mellitus (T2DM) prevention and management. We aimed to estimate dietary habits and diet-oriented knowledge as well as the level of physical activity in 2500 insulin-treated Polish type 2 diabetes mellitus (T2DM) patients (55.4% women). The mean age of the study participants was 64.9 ± 9.3 years, mean BMI was 31.4 kg/m(2) ± 4.5, mean diabetes duration was 12.4 ± 6.9 years, and mean baseline HbA1c was 8.5%  ± 1.2. At the study onset, all the patients completed a questionnaire concerning health-oriented behavior...
2016: International Journal of Endocrinology
https://www.readbyqxmd.com/read/27650783/progressing-insights-into-the-role-of-dietary-fats-in-the-prevention-of-cardiovascular-disease
#14
REVIEW
Peter L Zock, Wendy A M Blom, Joyce A Nettleton, Gerard Hornstra
Dietary fats have important effects on the risk of cardiovascular disease (CVD). Abundant evidence shows that partial replacement of saturated fatty acids (SAFA) with unsaturated fatty acids improves the blood lipid and lipoprotein profile and reduces the risk of coronary heart disease (CHD). Low-fat diets high in refined carbohydrates and sugar are not effective. Very long-chain polyunsaturated n-3 or omega-3 fatty acids (n-3 VLCPUFA) present in fish have multiple beneficial metabolic effects, and regular intake of fatty fish is associated with lower risks of fatal CHD and stroke...
November 2016: Current Cardiology Reports
https://www.readbyqxmd.com/read/27649232/sustaining-effect-of-intensive-nutritional-intervention-combined-with-health-education-on-dietary-behavior-and-plasma-glucose-in-type-2-diabetes-mellitus-patients
#15
Rui Fan, Meihong Xu, Junbo Wang, Zhaofeng Zhang, Qihe Chen, Ye Li, Jiaojiao Gu, Xiaxia Cai, Qianying Guo, Lei Bao, Yong Li
Diabetes mellitus is very common in elderly Chinese individuals. Although nutritional intervention can provide a balanced diet, the sustaining effect on at-home dietary behavior and long-term plasma glucose control is not clear. Consequently, we conducted a long-term survey following one month of experiential nutritional intervention combined with health education. Based on the Dietary Guidelines for a Chinese Resident, we found that the food items met the recommended values, the percentages of energy provided from fat, protein, and carbohydrate were more reasonable after one year...
September 13, 2016: Nutrients
https://www.readbyqxmd.com/read/27643725/short-term-safety-tolerability-and-efficacy-of-a-very-low-calorie-ketogenic-diet-interventional-weight-loss-program-versus-hypocaloric-diet-in-patients-with-type-2-diabetes-mellitus
#16
A Goday, D Bellido, I Sajoux, A B Crujeiras, B Burguera, P P García-Luna, A Oleaga, B Moreno, F F Casanueva
UNLABELLED: Brackground:The safety and tolerability of very low-calorie-ketogenic (VLCK) diets are a current concern in the treatment of obese type 2 diabetes mellitus (T2DM) patients. OBJECTIVE: Evaluating the short-term safety and tolerability of a VLCK diet (<50 g of carbohydrate daily) in an interventional weight loss program including lifestyle and behavioral modification support (Diaprokal Method) in subjects with T2DM. METHODS: Eighty-nine men and women, aged between 30 and 65 years, with T2DM and body mass index between 30 and 35 kg m(-)(2) participated in this prospective, open-label, multi-centric randomized clinical trial with a duration of 4 months...
September 19, 2016: Nutrition & Diabetes
https://www.readbyqxmd.com/read/27627075/-changes-in-nutritional-recommendations-for-a-healthy-population-and%C3%A2-their-influence-on-a-diabetic-diet
#17
Michal Anděl, Ludmila Brunerová, Pavel Dlouhý, Jan Polák, Jan Gojda, Pavel Kraml
UNLABELLED: Recently, thousands of papers brought knowledge about effects of nutrients on cellular level, in experimental animals and in human experiments on one side, the results of epidemiological studies on the other side have suggested the nutrients and foods for healthy diet and nutrients and foods, which should be consumed only in limited amount. Among foods, which should be avoided, those with higher content of trans-fatty acids. Their daily intake should not exceed 1 % of total energy intake...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27609769/weight-loss-following-diet-induced-obesity-does-not-alter-colon-tumorigenesis-in-the-aom-mouse-model
#18
Kandy T Velázquez, Reilly T Enos, Meredith S Carson, Taryn L Cranford, Jackie E Bader, Ioulia Chatzistamou, Udai P Singh, Prakash S Nagarkatti, Mitzi Nagarkatti, J Mark Davis, James A Carson, E Angela Murphy
Obesity presents a significant public health concern given its association with increased cancer incidence, unfavorable prognosis, and metastasis. However, there is very little literature on the effects of weight loss, following obesity, on risk for colon cancer or liver cancer. Therefore, we sought to study whether intentional weight loss through diet manipulation was capable of mitigating colon and liver cancer in mice. We fed mice with a high-fat diet (HFD) comprised of 47% carbohydrates, 40% fat, and 13% protein for 20 wk to mimic human obesity...
October 1, 2016: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/27560647/dietary-intake-and-cardiovascular-risk-factors-in-icelanders-following-voluntarily-a-low-carbohydrate-diet
#19
Anita S Elidottir, Thorhallur I Halldorsson, Ingibjörg Gunnarsdottir, Alfons Ramel
BACKGROUND/AIM: Most studies regarding low-carbohydrate diets (LCDs) have been intervention studies. The aim of the current study was to investigate dietary intake and cardiovascular risk factors among individuals who voluntarily follow a LCD. METHODS: A cross-sectional study was conducted (N = 54, 20-66yrs) in Reykjavik, Iceland. Participants recorded food intake for three days. Blood samples were analyzed for cardiovascular risk factors. RESULTS: Nearly half of the participants were obese and around 60% had been on a LCD for ≥ 6 months...
2016: PloS One
https://www.readbyqxmd.com/read/27557542/ketogenic-diet-and-cancer-a-perspective
#20
Christopher Smyl
Research of the last two decades showed that chronic low-grade inflammation, elevated blood glucose and insulin levels may play role in the onset of a number of non-communicable diseases such as type 2 diabetes and some forms of cancer. Regular exercise and fasting can ameliorate high blood glucose and insulin levels as well as increase the concentration of plasma ketone bodies. These, in consequence, may lead to reduction of inflammation. Exercise or severe restriction of caloric intake is not always advisable for patients, in particular those suffering from cancer...
2016: Recent Results in Cancer Research
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