keyword
MENU ▼
Read by QxMD icon Read
search

Bethesda

keyword
https://www.readbyqxmd.com/read/27913858/limitation-of-intraoperative-frozen-section-during-thyroid-surgery
#1
Sandrine Estebe, Cecile Montenat, Adrien Tremoureux, Chloé Rousseau, François Bouilloud, Franck Jegoux
Retrospective analysis on 312 patients, operated for thyroid nodules between 2014 and 2015, was conducted to evaluate the impact of frozen section analysis on the strategy of thyroid nodule surgery. One hundred and ninety-three patients were included. They all underwent preoperative US, fine needle aspiration cytology (FNAC), per operative frozen section (FS) and post operative definitive pathological analysis. Se, Sp, VPP and VPN of FNAC and FS were calculated and compared (McNemar's test). Multivariate analysis was performed to identify independent factor of good results...
December 2, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27911001/diagnostic-accuracy-of-thyroid-imaging-reporting-and-data-system-in-the-prediction-of-malignancy-in-nodules-with-atypia-and-follicular-lesion-of-undetermined-significance-cytologies
#2
Husniye Baser, Bekir Cakir, Oya Topaloglu, Afra Alkan, Sefika Burcak Polat, Hayriye Tatli Dogan, Mustafa Omer Yazicioğlu, Cevdet Aydin, Reyhan Ersoy
OBJECTIVE: Thyroid Imaging Reporting and Data System (TIRADS) is a simple and reliable reporting system for the prediction of malignancy. We aimed to determine the role of TIRADS in the prediction of malignancy in subcategories of Bethesda Category III, atypia of undetermined significance (AUS) and follicular lesion of undetermined significance (FLUS). DESIGN & PATIENTS: A total of 461 nodules with AUS cytology in 450 patients and 179 nodules with FLUS cytology in 168 patients were included...
November 7, 2016: Clinical Endocrinology
https://www.readbyqxmd.com/read/27906671/risk-stratification-of-thyroid-nodules-with-bethesda-category-iii-results-on-fine-needle-aspiration-cytology-the-additional-value-of-acoustic-radiation-force-impulse-elastography
#3
Chong-Ke Zhao, Hui-Xiong Xu, Jun-Mei Xu, Cheng-Yu Sun, Wei Chen, Bo-Ji Liu, Xiao-Wan Bo, Dan Wang, Shen Qu
To assess the value of conventional ultrasound, conventional strain elastography (CSE) and acoustic radiation force impulse (ARFI) elastography in differentiating likelihood of malignancy for Bethesda category III thyroid nodules. 103 thyroid nodules with Bethesda category III results on fine-needle aspiration cytology (FNAC) in 103 patients were included and all were pathologically confirmed after surgery. Conventional ultrasound, CSE and ARFI elastography including ARFI imaging and point shear wave speed (SWS) measurement were performed...
November 29, 2016: Oncotarget
https://www.readbyqxmd.com/read/27904904/clinical-evaluation-of-glycopegylated-recombinant-fviii-efficacy-and-safety-in-severe-haemophilia-a
#4
Paul Giangrande, Tatiana Andreeva, Pratima Chowdary, Silke Ehrenforth, Hideji Hanabusa, Frank W G Leebeek, Steven R Lentz, Laszlo Nemes, Lone Hvitfeldt Poulsen, Elena Santagostino, Chur Woo You, Wan Hui Ong Clausen, Peter G Jönsson, Johannes Oldenburg
Turoctocog alfa pegol (N8-GP) is a novel glycoPEGylated extended half-life recombinant factor VIII (FVIII) product developed for prophylaxis and treatment of bleeds in patients with haemophilia A, to enable higher activity levels with less frequent injections compared with standard FVIII products. This phase III (NCT01480180), multinational, open-label, non-randomised trial evaluated the safety and clinical efficacy of N8-GP when administered for treatment of bleeds and for prophylaxis, in previously treated patients aged ≥12 years with severe haemophilia A...
December 1, 2016: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/27904118/acquired-factor-v-inhibitors-in-a-patient-with-end-stage-renal-disease
#5
Atsushi Kitazawa, Hideo Misawa, Katsuhiro Nagahori, Ryo Koda, Atsunori Yoshino, Shinya Kawamoto, Tetsuro Takeda
We report a case of acquired factor V inhibitors (AFVIs) in a patient with end-stage renal disease receiving warfarin therapy for atrial fibrillation. A 72-year-old Japanese man was admitted to our hospital complaining of tarry stools and abdominal pain. The laboratory findings revealed eosinophilia (52.1%), prolonged activated partial thromboplastin time (APTT) (98 s), PT (84 s), a factor V (FV) activity of <3%, and an FV inhibitor level of 6 Bethesda units/mL. After administration of prednisolone was started, his coagulation findings improved...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27902587/influence-of-factor-viii-level-and-its-inhibitor-titer-on-the-therapeutic-response-to-corticosteroids-alone-in-the-management-of-acquired-hemophilia-a-retrospective-single-center-study
#6
Mathieu Vautier, Hubert de Boysson, Christian Creveuil, Yohan Repesse, Annie Borel-Derlon, Xavier Troussard, Gandhi L Damaj, Boris Bienvenu, Philippe Gautier, Achille Aouba
The treatment of acquired hemophilia (AH) involves discussing whether corticosteroids should be administered alone or combined with immunosuppressant drugs, which increase the risk of infection especially in elderly patients and/or those with autoimmunity or neoplastic diseases, who represent the target population of the disease. Prognostic factors highlighting adequate responses to corticosteroids alone must be identified for satisfactory clinical response and lower infectious risk.We aimed to evaluating the efficacy of corticosteroids alone in the management of AH depending on factor VIII (FVIII, ≥ or <1 IU/dL) levels and/or inhibitor (INH, ≤ or >20 Bethesda units per milliliter [BU/mL]) titer...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27900100/avoidance-of-unnecessary-fine-needle-aspiration-with-the-use-of-the-thyroid-imaging-reporting-data-system-classification-and-strain-elastography-based-on-the-bethesda-system-for-reporting-thyroid-cytopathology
#7
Murat Erkan, Sule Canberk, Gamze Z Kilicoglu, Mine Onenerk, Atay Uludokumaci, Pembegul Gunes, Tugba Atasoy
Thyroid fine-needle aspiration (FNA) biopsy has been widely accepted as an accurate and cost-effective tool in the management of thyroid nodules. To avoid unnecessary FNAs and provide appropriate management, patient evaluation should be based on a multidisciplinary approach. For this purpose, the Thyroid Imaging Reporting and Data System (TI-RADS) and strain elastography (SE) were proposed as tools for the risk assessment of malignancy in thyroid nodules. The aim of the present study was to analyze the utility of TI-RADS system and SE, along with FNA, and prospectively evaluate 369 consecutive patients referred for FNA of a thyroid nodule...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27893191/young-investigator-challenge-molecular-testing-in-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features
#8
Xiaoyin Sara Jiang, Grant P Harrison, Michael B Datto
BACKGROUND: Molecular testing provides an important ancillary study for thyroid nodules with indeterminate cytology. The nomenclature shift to "noninvasive follicular thyroid neoplasm with papillary-like nuclear features" (NIFTP) will impact the performance of molecular tests. For the current study, the authors reviewed the performance of the Afirma gene-expression classifier (GEC) and the University of Pittsburgh Medical Center (UPMC) targeted mutation panel tests in thyroid nodules that were subsequently diagnosed as NIFTP on surgical resection...
November 28, 2016: Cancer
https://www.readbyqxmd.com/read/27889996/elevated-microsatellite-alterations-at-selected-tetranucleotide-repeats-emast-and-microsatellite-instability-in-patients-with-colorectal-cancer-and-its-clinical-features
#9
H S Lee, K U Park, D-W Kim, M H Ihn, W H Kim, A N Seo, H E Chang, S K Nam, S Y Lee, H-K Oh, S-B Kang
PURPOSE: Recently, a different type of microsatellite instability (MSI) instability designated 'elevated microsatellite alterations at selected tetranucleotide repeats' (EMAST) has been reported in several neoplasms, but its clinical implications remain unclear. We aimed to determine the relationships among EMAST, MSI and clinicopathologic characteristics, including oncologic outcomes, in colorectal cancer (CRC). MATERIALS AND METHODS: We evaluated 100 sporadic CRC cases subjected to surgery using five markers (MYCL1, D9S242, D20S85, D8S321, and D20S82) for EMAST and the Bethesda panel for MSI status...
November 23, 2016: Current Molecular Medicine
https://www.readbyqxmd.com/read/27886713/automated-classification-of-pap-smear-images-to-detect-cervical-dysplasia
#10
Kangkana Bora, Manish Chowdhury, Lipi B Mahanta, Malay Kumar Kundu, Anup Kumar Das
BACKGROUND AND OBJECTIVES: The present study proposes an intelligent system for automatic categorization of Pap smear images to detect cervical dysplasia, which has been an open problem ongoing for last five decades. METHODS: The classification technique is based on shape, texture and color features. It classifies the cervical dysplasia into two-level (normal and abnormal) and three-level (Negative for Intraepithelial Lesion or Malignancy, Low-grade Squamous Intraepithelial Lesion and High-grade Squamous Intraepithelial Lesion) classes reflecting the established Bethesda system of classification used for diagnosis of cancerous or precancerous lesion of cervix...
January 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/27882552/trends-and-the-utilization-of-transoral-robotic-surgery-with-neck-dissection-in-new-york-state
#11
Catherine H Frenkel, Jie Yang, Mengru Zhang, Elliot Regenbogen, Dana A Telem, Ghassan J Samara
OBJECTIVES: The timing of neck dissection (ND) in relation to transoral robotic surgery (TORS) is controversial. This study identifies local practice patterns and economic and social access disparities during adoption of TORS. STUDY DESIGN: We analyzed utilization patterns of TORS and ND using the New York Statewide Planning and Research Cooperative System all-payer administrative database. Statewide head and neck cancer incidence from the Centers for Disease Control and Prevention (Bethesda, MD) was used to control for overall cancer incidence...
November 24, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27872683/safe-and-effective-sofosbuvir-based-therapy-in-patients-with-mental-health-disease-on-hepatitis-c-virus-treatment
#12
Lydia Shuk Yee Tang, Jack Masur, Zayani Sims, Amy Nelson, Anu Osinusi, Anita Kohli, Sarah Kattakuzhy, Michael Polis, Shyam Kottilil
AIM: To study impact of baseline mental health disease on hepatitis C virus (HCV) treatment; and Beck's Depression Inventory (BDI) changes with sofosbuvir- and interferon-based therapy. METHODS: This is a retrospective cohort study of participants from 5 studies enrolled from single center trials conducted at the Clinical Research Center of the National Institutes of Health, Bethesda, MD, United States. All participants were adults with chronic HCV genotype 1 infection and naïve to HCV therapy...
November 8, 2016: World Journal of Hepatology
https://www.readbyqxmd.com/read/27867809/fixation-of-split-thickness-skin-graft-using-fast-clotting-fibrin-glue-containing-undiluted-high-concentration-thrombin-or-sutures-a-comparison-study
#13
Hyun Ho Han, Daiwon Jun, Suk-Ho Moon, In Sook Kang, Min Cheol Kim
OBJECTIVE: For skin defects caused by full-thickness burns, trauma, or tumor tissue excision, skin grafting is one of the most convenient and useful treatment methods. In this situation, graft fixation is important in skin grafting. This study was performed to compare the effectiveness of skin graft fixation between high-concentration fibrin sealant and sutures. There have been numerous studies using fibrin sealant for graft fixation, but they utilized slow-clotting fibrin sealant containing less than 10 IU/mL thrombin...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27860048/the-growing-problem-of-antimicrobial-resistance
#14
Palle Holmstrup, Bjarne Klausen
Antibiotic therapy over the years has saved millions of lives, but antimicrobial resistance (AMR) is a current threat to human health. An interesting review on AMR has recently been presented in the Journal of American Medical Association (Marston et al., 2016). The review is authored by five staff members at National Institutes of Health in Bethesda, Maryland, and the purpose of the review was to identify factors associated with AMR, the current epidemiology of important resistant organisms, and possible solutions to the AMR problem...
November 17, 2016: Oral Diseases
https://www.readbyqxmd.com/read/27859783/practical-usefulness-of-atypical-endometrial-cell-categories-within-the-new-classification-of-endometrial-cytology-when-applied-to-conventional-smears
#15
S Munakata, S Sasaki, M Takase, R Okatake, Y Suzuki, T Yamamoto, K Yanoh
OBJECTIVE: Endometrial cytology has been widely used as a screening tool in Japan. Traditionally, a three-tier reporting system, consisting of 'negative', 'suspicious' and 'positive' categories, has been used. However, a more descriptive system, the New Terminology in Endometrial Cytology (NTEMC), which is based on the Bethesda System for uterine cervical cytology, was introduced recently. The objective of this study was to validate the NTEMC criteria. METHODS: Endometrial cytology specimens that had been categorised as 'suspicious' were collected in our hospital between 2003 and 2013, and from these, 106 specimens with corresponding histological results, were re-evaluated according to the NTEMC criteria...
November 17, 2016: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/27858974/report-and-research-agenda-of-the-american-geriatrics-society-and-national-institute-on-aging-bedside-to-bench-conference-on-sleep-circadian-rhythms-and-aging-new-avenues-for-improving-brain-health-physical-health-and-functioning
#16
Constance H Fung, Michael V Vitiello, Cathy A Alessi, George A Kuchel
The American Geriatrics Society, with support from the National Institute on Aging and other funders, held its eighth Bedside-to-Bench research conference, entitled "Sleep, Circadian Rhythms, and Aging: New Avenues for Improving Brain Health, Physical Health and Functioning," October 4 to 6, 2015, in Bethesda, Maryland. Part of a conference series addressing three common geriatric syndromes-delirium, sleep and circadian rhythm (SCR) disturbance, and voiding dysfunction-the series highlighted relationships and pertinent clinical and pathophysiological commonalities between these three geriatric syndromes...
November 14, 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27852075/thyroid-atypia-follicular-lesion-of-undetermined-significance-attitudes-towards-the-diagnosis-of-bethesda-system-iii-nodules
#17
Lourdes Estrada Muñoz, Cristina Díaz Del Arco, Luis Ortega Medina, M Jesús Fernández Aceñero
OBJECTIVES: To review our institutional experience and to analyze the clinical decisions made after a cytological diagnosis of atypia of undetermined significance or follicular lesion of undetermined significance (AUS/FLUS). STUDY DESIGN: This is a retrospective review of all thyroid fine-needle aspiration (FNA) cytologies performed in the Hospital Clínico San Carlos (Madrid) between 2010 and 2014. RESULTS: One hundred thirty thyroid FNA were categorized as AUS/FLUS (5%)...
November 17, 2016: Acta Cytologica
https://www.readbyqxmd.com/read/27849500/the-u-s-army-occupational-and-environmental-medicine-residency-at-aberdeen-proving-ground-maryland-1960-1996
#18
Joel C Gaydos, Timothy M Mallon, William A Rice
BACKGROUND: Reorganization of the Army and critical assessment of Army Graduate Medical Education programs prompted the Occupational and Environmental Medicine (OEM) Consultant to the Army Surgeon General to initiate a review of current Army OEM residency training. Available information indicated the Army OEM residency at Aberdeen Proving Ground, MD, was the first and longest operating Army OEM residency. Describing this residency was identified as the first step in the review, with the objectives of determining why the residency was started and sustained and its relevance to the needs of the Army...
November 2016: Military Medicine
https://www.readbyqxmd.com/read/27847394/sex-determination-of-adult-human-maxillary-sinuses-on-panoramic-radiographs
#19
Cristhiane Leao de Queiroz, Andrea Sayuri Silveira Dias Terada, Thais Uenoyama Dezem, Lais Gomes de Araújo, Rodrigo Galo, Christiano Oliveira-Santos, Ricardo Henrique Alves da Silva
The purpose of this study was to evaluate dimensions of adult human maxillary sinuses on panoramic radiographs and their possible application on the sex determination for forensic purposes. The sample comprised 64 database panoramic radiographs from individuals aged 20 years or older (32 male and 32 female subjects), with complete permanent dentition (or absence of third molars). One examiner measured the width and height of the right and left maxillary sinuses using the software Image J 1.47v (National Institutes of Health, Bethesda, USA)...
September 2016: Acta Stomatologica Croatica
https://www.readbyqxmd.com/read/27826468/digital-analysis-of-eyelid-features-and-eyebrow-position-following-co2-laser-assisted-blepharoptosis-surgery
#20
Xiaodong Zheng, Hirohiko Kakizaki, Tomoko Goto, Atsushi Shiraishi
BACKGROUND: To compare the margin reflex distance of the upper (MRD-1) and lower (MRD-2) eyelids and the eyebrow height (EBH) in patients with involutional and hard contact lens wear--induced blepharoptosis before and after ptosis surgery. METHODS: Sixty patients with acquired blepharoptosis were studied. Group 1 consisted of 30 patients with involutional ptosis (age, 75.8 ± 6.4 years), and group 2 consisted of 30 patients with hard contact lens wear-induced ptosis (age, 50...
October 2016: Plastic and Reconstructive Surgery. Global Open
keyword
keyword
4860
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"