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https://www.readbyqxmd.com/read/29166710/-effects-of-hydrogen-on-the-lung-damage-of-mice-at-early-stage-of-severe-burn
#1
C Qin, Y X Bian, T T Feng, J H Zhang, Y H Yu
Objective: To investigate the effects of hydrogen on the lung damage of mice at early stage of severe burn. Methods: One hundred and sixty ICR mice were divided into sham injury, hydrogen, pure burn, and burn+ hydrogen groups according to the random number table, with 40 mice in each group. Mice in pure burn group and burn+ hydrogen group were inflicted with 40% total body surface area full-thickness scald (hereafter referred to as burn) on the back, while mice in sham injury group and hydrogen group were sham injured...
November 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29166709/-effects-of-dexmedetomidine-on-myocardium-of-rats-with-severe-burn-at-early-stage
#2
D Wang, P L Yang, X Zhang, Y Liu
Objective: To investigate the effects of dexmedetomidine on myocardium of rats at early stage after severe burn. Methods: Twenty specific pathogen free male SD rats were immersed in 90 ℃ hot water for 20 s, causing 30% total body surface area (TBSA) full-thickness scald (hereafter referred to as burn) on the back. And then they were divided into burn resuscitation group (BR) and burn resuscitation+ dexmedetomidine group (BRD) according to the random number table, with 10 rats in each group. Sodium lactate Ringer's solution (2 mL·kg(-1)·%TBSA(-1)) were intraperitoneally injected into rats of both groups after burn...
November 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29166708/-effects-of-astragalus-polysaccharide-on-cardiac-dysfunction-in-rabbits-with-severe-scald-injury
#3
L Zhong, J H Zhan, J H Luo, X Cheng
Objective: To investigate the effects of astragalus polysaccharide (AP) on cardiac dysfunction in rabbits with severe scald injury. Methods: Sixty-four New Zealand white rabbits were divided into pure scald group and AP group according to the random number table, with 32 rabbits in each group. Rabbits in the two groups were all inflicted with 30% total body surface area full-thickness scald on the back. Immediately after injury, rabbits in two groups were intraperitoneally injected with lactated Ringer's solution once for antishock...
November 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29166319/cardiometabolic-impact-of-changing-sitting-standing-and-stepping-in-the-workplace
#4
Elisabeth Ah Winkler, Sebastien Chastin, Elizabeth G Eakin, Neville Owen, Anthony D LaMontagne, Marj Moodie, Paddy C Dempsey, Bronwyn A Kingwell, David W Dunstan, Genevieve N Healy
BACKGROUND: According to cross-sectional and acute experimental evidence, reducing sitting time should improve cardio-metabolic health risk biomarkers. Furthermore, the improvements obtained may depend on whether sitting is replaced with standing or ambulatory activities. Based on data from the Stand Up Victoria multi-component workplace intervention, we examined this issue using compositional data analysis - a method that can examine and compare all activity changes simultaneously. METHODS: Participants receiving the intervention (n=136 ≥0...
November 21, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29166079/strong-correlation-in-incremental-full-configuration-interaction
#5
Paul M Zimmerman
Incremental Full Configuration Interaction (iFCI) reaches high accuracy electronic energies via a many-body expansion of the correlation energy. In this work, the Perfect Pairing (PP) ansatz replaces the Hartree-Fock reference of the original iFCI method. This substitution captures a large amount of correlation at zero-order, which allows iFCI to recover the remaining correlation energy with low-order increments. The resulting approach, PP-iFCI, is size consistent, size extensive, and systematically improvable with increasing order of incremental expansion...
June 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29165731/effects-of-the-actn3-r577x-genotype-on-the-muscular-strength-and-range-of-motion-before-and-after-eccentric-contractions-of-the-elbow-flexors
#6
Naoki Kikuchi, Yosuke Tsuchiya, Koichi Nakazato, Naokata Ishii, Eisuke Ochi
The purpose of present study was to examine the association between ACTN3 R577X genotype and functional characteristics of elbow flexors before and after isokinetic eccentric contractions (ECCs). Fifty-two men (age: 20.8±3.8 years, height: 172.5±5.9 cm, body mass: 64.7±6.5 kg, BMI: 21.7±1.7) who had not participated in any regular resistance training for at least 1 year prior to this study were recruited. ECCs consisted of five sets of six maximal voluntary isokinetic (30°/s) ECCs of the elbow flexors with a range of motion (ROM) from 90° flexion to 0° (full extension)...
November 17, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29164776/nutritional-screening-and-dietitian-consultation-rates-in-a-geriatric-evaluation-and-management-unit
#7
Elsa Dent, Olivia Wright, Emiel O Hoogendijk, Ruth E Hubbard
AIM: Nutritional screening may not always lead to intervention. The present study aimed to determine: (i) the rate of nutritional screening in hospitalised older adults; (ii) whether nutritional screening led to dietitian consultation and (iii) factors associated with malnutrition. METHODS: In this prospective study of patients aged ≥70 years admitted to a Geriatric Evaluation and Management Unit (GEMU), malnutrition was screened for using the Mini Nutritional Assessment Short Form (MNA-SF) and identified using the Mini Nutritional Assessment (MNA)...
November 22, 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/29164228/emg-driven-forward-dynamics-simulation-to-estimate-in-vivo-joint-contact-forces-during-normal-smooth-and-bouncy-gait
#8
Swithin Razu, Trent M Guess
This study leveraged data from the "Sixth Grand Challenge Competition to Predict in Vivo Knee Loads" to create a full-body musculoskeletal model that incorporates subject specific geometries of the right leg in order to concurrently predict knee contact forces, ligament forces, muscle forces, and ground contact forces. The objectives of this paper are twofold: First, to describe an electromyography (EMG)-driven modeling methodology to predict knee contact forces, and second to validate model predictions by evaluating the model predictions against known values for a patient with an instrumented total knee replacement (TKR) for three distinctly different gait styles (normal, smooth, and bouncy gait)...
November 21, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29164167/single-leg-hop-test-performance-and-isokinetic-knee-strength-after-anterior-cruciate-ligament-reconstruction-in-athletes
#9
Ted Sueyoshi, Akihiro Nakahata, Gen Emoto, Tomoki Yuasa
Background: Isokinetic strength and hop tests are commonly used to assess athletes' readiness to return to sport after knee surgery. Purpose/Hypothesis: The purpose of this study was to investigate the results of single-leg hop and isokinetic knee strength testing in athletes who underwent anterior cruciate ligament reconstruction (ACLR) upon returning to sport participation as well as to study the correlation between these 2 test batteries. The secondary purpose was to compare the test results by graft type (patellar tendon or hamstring)...
November 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29163952/in-office-arthroscopy-for-the-evaluation-of-chronic-knee-pain-a-case-report
#10
Jacob A West, Nirav H Amin
This is a case report detailing the use of in-office needle arthroscopy (mi-eye 2™) in a patient with chronic knee pain and inconclusive magnetic resonance imaging findings. The patient is a 40-year-old male who presented to our clinic after an extended history of right knee pain along the medial aspect with previous failed treatments. Magnetic resonance imaging without contrast had demonstrated full-thickness chondral fissuring of the lateral patellar facet, mild abnormal signals of the proximal patellar tendon and Hoffa's fat pad, and intact anterior cruciate ligament and posterior cruciate ligament...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/29163414/control-of-antimicrobial-resistance-requires-an-ethical-approach
#11
REVIEW
Ben Parsonage, Philip K Hagglund, Lloyd Keogh, Nick Wheelhouse, Richard E Brown, Stephanie J Dancer
Ethical behavior encompasses actions that benefit both self and society. This means that tackling antimicrobial resistance (AMR) becomes an ethical obligation, because the prospect of declining anti-infectives affects everyone. Without preventive action, loss of drugs that have saved lives over the past century, will condemn ourselves, people we know, and people we don't know, to unacceptable risk of untreatable infection. Policies aimed at extending antimicrobial life should be considered within an ethical framework, in order to balance the choice, range, and quality of drugs against stewardship activities...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29163361/girls-with-a-history-of-premature-adrenarche-have-advanced-growth-and-pubertal-development-at-the-age-of-12-years
#12
Jani Liimatta, Pauliina Utriainen, Raimo Voutilainen, Jarmo Jääskeläinen
Background: Premature adrenarche (PA) has been linked to early thelarche and menarche, but longitudinal data on growth and pubertal development after PA are insufficient. Methods: Growth and pubertal development of mostly full-term and appropriate for gestational age-born 43 PA (36 girls) and 63 control children (52 girls) were analyzed prospectively. Children examined first at the mean age of 7.6 years were reexamined at the mean age of 12.0 years. Results: The PA girls but not the boys were taller and had higher body mass index (BMI) than the controls...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29163212/regulation-of-skeletal-muscle-plasticity-by-protein-arginine-methyltransferases-and-their-potential-roles-in-neuromuscular-disorders
#13
REVIEW
Derek W Stouth, Tiffany L vanLieshout, Nicole Y Shen, Vladimir Ljubicic
Protein arginine methyltransferases (PRMTs) are a family of enzymes that catalyze the methylation of arginine residues on target proteins, thereby mediating a diverse set of intracellular functions that are indispensable for survival. Indeed, full-body knockouts of specific PRMTs are lethal and PRMT dysregulation has been implicated in the most prevalent chronic disorders, such as cancers and cardiovascular disease (CVD). PRMTs are now emerging as important mediators of skeletal muscle phenotype and plasticity...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29162619/updated-systematic-review-of-exercise-studies-in-breast-cancer-survivors-attention-to-the-principles-of-exercise-training
#14
REVIEW
Sarah E Neil-Sztramko, Kerri M Winters-Stone, Kelcey A Bland, Kristin L Campbell
OBJECTIVES: To update our previous evaluation of the exercise interventions used in randomised controlled trials of breast cancer survivors in relation to (1) the application of the principles of exercise training in the exercise prescription; (2) the reporting of the components of the exercise prescription; and (3) the reporting of adherence of participants to the prescribed interventions. DESIGN: Systematic review. DATA SOURCES: The OVID Medline, Embase, CINAHL and SPORTDiscus electronic databases were searched from January 2010 to January 2017...
November 21, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29162577/cohort-profile-the-mayo-clinic-cohort-study-of-oophorectomy-and-aging-2-moa-2-in-olmsted-county-minnesota-usa
#15
Walter A Rocca, Liliana Gazzuola Rocca, Carin Y Smith, Brandon R Grossardt, Stephanie S Faubion, Lynne T Shuster, Elizabeth A Stewart, Michelle M Mielke, Kejal Kantarci, Virginia M Miller
PURPOSE: This cohort study was established to investigate the effects of unilateral and bilateral oophorectomy on the ageing processes in women. PARTICIPANTS: We used the records-linkage system of the Rochester Epidemiology Project (REP, http://www.rochesterproject.org) to identify 570 women who underwent unilateral oophorectomy and 1653 women who underwent bilateral oophorectomy in Olmsted County, Minnesota from 1988 through 2007 (20 years). Each woman was matched by age (±1 year) to a population-based referent woman who had not undergone any oophorectomy (570 referent women) or bilateral oophorectomy (1653 referent women)...
November 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/29162153/managing-toxicities-associated-with-immune-checkpoint-inhibitors-consensus-recommendations-from-the-society-for-immunotherapy-of-cancer-sitc-toxicity-management-working-group
#16
I Puzanov, A Diab, K Abdallah, C O Bingham, C Brogdon, R Dadu, L Hamad, S Kim, M E Lacouture, N R LeBoeuf, D Lenihan, C Onofrei, V Shannon, R Sharma, A W Silk, D Skondra, M E Suarez-Almazor, Y Wang, K Wiley, H L Kaufman, M S Ernstoff
Cancer immunotherapy has transformed the treatment of cancer. However, increasing use of immune-based therapies, including the widely used class of agents known as immune checkpoint inhibitors, has exposed a discrete group of immune-related adverse events (irAEs). Many of these are driven by the same immunologic mechanisms responsible for the drugs' therapeutic effects, namely blockade of inhibitory mechanisms that suppress the immune system and protect body tissues from an unconstrained acute or chronic immune response...
November 21, 2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/29161903/spatial-resolution-measurements-using-radia-diagnostic-software-with-sedentexct-image-quality-phantom-in-cone-beam-ct-for-dental-use
#17
Hiroshi Watanabe, Yoshikazu Nomura, Ami Kuribayashi, Tohru Kurabayashi
OBJECTIVES: We aimed to employ the Radia diagnostic software with the Safety and Efficacy of a New Emerging Dental X-ray Modality (SEDENTEXCT) image quality (IQ) phantom in computed tomography (CT), and to evaluate its validity. METHODS: The SEDENTEXCT IQ phantom and Radia diagnostic software were employed. The phantom was scanned using one medical full-body CT and two dento-maxillo-facial cone beam CTs. The obtained images were imported to the Radia software, and the spatial resolution outputs were evaluated...
November 21, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/29159880/swim-bladder-mycosis-in-pretty-tetra-hemigrammus-pulcher-caused-by-exophiala-pisciphila-and-phaeophleospora-hymenocallidicola-and-experimental-verification-of-pathogenicity
#18
J Řehulka, A Kubátová, V Hubka
Spontaneous invasive and chronic disseminated mycosis affected Hemigrammus pulcher kept in a public aquarium, and infection was manifested by inappetence, exophthalmia, erratic swimming, eroded scales, anaemia of the gills and abdominal distension. Internally, there was a grossly swollen swim bladder with a thickened wall filled with a dark mass. The body cavities contained a clear, light amber fluid and a swollen intestine which was full of a watery fluid containing small gas bubbles. Histopathology revealed a granulomatous inflammatory response with fungal hyphae in the lumen and wall of the swim bladder, hepatopancreas, spleen and kidneys with signs of nephrohydrosis...
November 21, 2017: Journal of Fish Diseases
https://www.readbyqxmd.com/read/29159533/reduced-bone-mineral-density-in-human-immunodeficiency-virus-infected-individuals-a-meta-analysis-of-its-prevalence-and-risk-factors
#19
S S L Goh, P S M Lai, A T B Tan, S Ponnampalavanar
A meta-analysis was conducted to evaluate the prevalence of osteopenia/osteoporosis in human immunodeficiency virus (HIV)-infected individuals. The prevalence of osteopenia/osteoporosis in HIV-infected and antiretroviral therapy (ART)-treated individuals was significantly higher than respective controls. Evidence regarding bone loss within first year of HIV infection or ART initiation was preliminary. PURPOSE: The aim of the study is to systematically review published literature on the prevalence of osteopenia/osteoporosis and its associated risk factors in HIV-infected individuals...
November 20, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/29158981/fitness-implications-of-sex-specific-catch-up-growth-in-nephila-senegalensis-a-spider-with-extreme-reversed-ssd
#20
Rainer Neumann, Nicole Ruppel, Jutta M Schneider
Background: Animal growth is often constrained by unfavourable conditions and divergences from optimal body size can be detrimental to an individual's fitness, particularly in species with determinate growth and a narrow time-frame for life-time reproduction. Growth restriction in early juvenile stages can later be compensated by means of plastic developmental responses, such as adaptive catch-up growth (the compensation of growth deficits through delayed development). Although sex differences regarding the mode and degree of growth compensation have been coherently predicted from sex-specific fitness payoffs, inconsistent results imply a need for further research...
2017: PeerJ
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