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https://www.readbyqxmd.com/read/28719834/the-exon3-deleted-growth-hormone-receptor-gene-polymorphism-d3-ghr-is-associated-with-insulin-and-spontaneous-growth-in-short-sga-children-nesgas
#1
Mathilde Gersel Wegmann, Ajay Thankamony, Edna Roche, Hilary Hoey, Jeremy Kirk, Guftar Shaikh, Sten-A Ivarsson, Olle Söder, David B Dunger, Anders Juul, Rikke Beck Jensen
OBJECTIVE: The effect of a common polymorphism in the Growth Hormone (GH) receptor (d3-GHR) gene on growth, metabolism and body composition was examined in short children born small for gestational age (SGA) on GH treatment. DESIGN: In 96 prepubertal, short SGA children treated with high-dose GH (67μg/kg/day) in the NESGAS study, insulin sensitivity (IS), insulin secretion and disposition index (DI) were determined during the first year of treatment. Body composition was analysed by DXA...
July 12, 2017: Growth Hormone & IGF Research
https://www.readbyqxmd.com/read/28718273/3d-quantitative-evaluation-of-spine-proprioceptive-perception-motor-control-through-instinctive-self-correction-manoeuvre-in-healthy-young-subjects-posture-an-observational-study
#2
Moreno D'Amico, Edyta Kinel, Piero Roncoletta
BACKGROUND: Conservative treatment in spine deformities and spine related disorders is mainly based on proper individual proprioceptive and motor control training. For these reasons, conservative treatment involves the stimulation of individual capability of perceiving/reducing deformities, blocks and/or improper spine posture by voluntary control. The literature describes that habitually adopted relaxed postures often exacerbate low back pain. Typically, youths can be referred to therapeutic programs aimed at improving the quality of body posture along with fostering the awareness of the importance of correct posture...
July 18, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28716983/systematic-review-of-the-cost-and-cost-effectiveness-of-rapid-endovascular-therapy-for-acute-ischemic-stroke
#3
Laura K Sevick, Sarah Ghali, Michael D Hill, Vishva Danthurebandara, Diane L Lorenzetti, Tom Noseworthy, Eldon Spackman, Fiona Clement
BACKGROUND AND PURPOSE: Rapid endovascular therapy (EVT) is an emerging treatment option for acute ischemic stroke. Several economic evaluations have been published examining the cost-effectiveness of EVT, and many international bodies are currently making adoption decisions. The objective of this study was to establish the cost-effectiveness of EVT for ischemic stroke patients and to synthesize all the publicly available economic literature. METHODS: A systematic review of the published literature was conducted to identify economic evaluations and cost analyses of EVT for acute ischemic stroke patients...
July 17, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28716692/the-fatigue-of-a-full-body-resistance-exercise-session-in-trained-men
#4
Paul W M Marshall, Rebecca Cross, Michael Haynes
OBJECTIVES: We examined the fatigue and recovery for 48h following a full-body resistance exercise session in trained men. DESIGN: Experimental cross-sectional study. METHODS: Eight resistance trained men volunteered to participate (mean±SD; age 27.0±6.0 years, height 1.79±0.05m, weight 81.8±6.8kg, training experience 7.8±5.0 years). Fatigue and pain was measured before, after, 1h post, 24h and 48h post the full-body resistance exercise session, which was based on in-season models used in contact team sports (e...
July 4, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28715584/reduced-retinal-vessel-density-in-obstructive-sleep-apnea-syndrome-patients-an-optical-coherence-tomography-angiography-study
#5
Jian Yu, Kuanlin Xiao, Jingjing Huang, Xinghuai Sun, Chunhui Jiang
Purpose: To examine the retinal vasculature in patients with obstructive sleep apnea-hypopnea syndrome (OSAS) and to determine the correlation between retinal vascularity and the severity of OSAS. Design: Prospective, cross-sectional study. Methods: Sixty-nine consecutive subjects who underwent polysomnography were enrolled. Patients were divided into three groups according to the severity of OSAS, which was defined using the apnea-hypopnea index (AHI) as normal-to-mild (AHI <15), moderate (≥15 to <30), or severe (≥30)...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28715482/impact-of-maternal-body-mass-index-and-gestational-weight-gain-on-neonatal-outcomes-among-healthy-middle-eastern-females
#6
Tatiana Papazian, Georges Abi Tayeh, Darine Sibai, Hala Hout, Imad Melki, Lydia Rabbaa Khabbaz
BACKGROUND: Studies on the relative impact of body mass index in women in childbearing age and gestational weight gain on neonatal outcomes are scarce in the Middle East. OBJECTIVES: The primary objective of this research was to assess the impact of maternal body mass index (BMI) and gestational weight gain (GWG) on neonatal outcomes. The effect of maternal age and folic acid supplementation before and during pregnancy was also examined. SUBJECTS AND METHODS: This is a retrospective cross sectional observational study of 1000 full term deliveries of women enrolled thru the National Collaborative Perinatal Neonatal Network, in Lebanon...
2017: PloS One
https://www.readbyqxmd.com/read/28715310/discovering-ways-to-mend-growing-bodies-the-bioengineering-of-devices-for-the-youngest-patients-brings-unique-challenges-and-rewards
#7
David L Chandler
Some babies are born with a rare condition known as esophageal atresia, in which part of the connection between the throat and stomach is missing or nonfunctional. While this was once untreatable and fatal, in recent years surgeons have developed a method using traction to stretch the tissues out on each end until, over time, they are long enough to be sewn together and so substitute for the missing portion of the esophagus. The procedure has allowed many infant patients to go home with a full, normal life ahead of them...
July 2017: IEEE Pulse
https://www.readbyqxmd.com/read/28715283/temperate-water-immersion-as-a-treatment-for-hyperthermic-humans-wearing-american-football-uniforms
#8
Kevin C Miller, Tyler Truxton, Blaine Long
CONTEXT:   Cold-water immersion (CWI; 10°C) can effectively reduce body core temperature even if a hyperthermic human is wearing a full American football uniform (PADS) during treatment. Temperate-water immersion (TWI; 21°C) may be an effective alternative to CWI if resources for the latter (eg, ice) are unavailable. OBJECTIVE:   To measure rectal temperature (Trec) cooling rates, thermal sensation, and Environmental Symptoms Questionnaire (ESQ) scores of participants wearing PADS or shorts, undergarments, and socks (NOpads) before, during, and after TWI...
July 17, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28715054/sustainability-of-prevention-practices-at-the-workplace-safety-simplification-productivity-and-effectiveness
#9
A Messineo, M S Cattaruzza, C Prestigiacomo, F Giordano, L T Marsella
Traditional full-time employment has evolved into various types of occupational situations, and, nowadays, new work organization strategies have been developed. Previously overlooked risk factors have emerged, such as traffic accidents while commuting or during work hours, poor work organization, and detrimental lifestyles (like alcohol and substance abuse, although recent statistics seem to show a declining trend for the latter). The global scenario shows greater attention to occupational risks, but also, to the reduced degree of protection...
September 2017: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/28714541/full-night-measurement-of-level-of-obstruction-in-sleep-apnea-utilizing-continuous-manometry
#10
Hahn Jin Jung, Jee Hye Wee, Chae-Seo Rhee, Jeong-Whun Kim
OBJECTIVES/HYPOTHESIS: To determine the average proportion of retropalatal or retroglossal obstruction occurring during a whole night in single patients with obstructive sleep apnea. STUDY DESIGN: Retrospective analysis. METHODS: Patients who underwent full-night polysomnography and upper airway pressure manometry at the same time were retrospectively enrolled. Airway obstruction levels were categorized into retropalatal or retroglossal obstruction according to the pressure change shown during pressure manometry...
July 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28713734/treatment-of-micrognathia-by-intraoral-distraction-osteogenesis-a-prospective-study
#11
M Baskaran, S Gidean Arularasan, T K Divakar, Rohini Thirunavukkarasu
PURPOSE: Maxillofacial deformities are always psychologically and physically distressing to the patients and is also challenging to the treating surgeons. The term Micrognathia means a "small jaw". True micrognathia, where the maxilla or the mandibular skeleton does not grow to the full size can be congenital or acquired. Distraction osteogenesis also called as callus distraction or callostasis or osteodistraction or distraction histogenesis is a biological process of regenerating newly formed bone and adjacent soft tissue by a gradual and controlled traction of surgically separated bone segments...
January 2017: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28713281/effectiveness-of-traditional-strength-vs-power-training-on-muscle-strength-power-and-speed-with-youth-a-systematic-review-and-meta-analysis
#12
REVIEW
David G Behm, James D Young, Joseph H D Whitten, Jonathan C Reid, Patrick J Quigley, Jonathan Low, Yimeng Li, Camila D Lima, Daniel D Hodgson, Anis Chaouachi, Olaf Prieske, Urs Granacher
Numerous national associations and multiple reviews have documented the safety and efficacy of strength training for children and adolescents. The literature highlights the significant training-induced increases in strength associated with youth strength training. However, the effectiveness of youth strength training programs to improve power measures is not as clear. This discrepancy may be related to training and testing specificity. Most prior youth strength training programs emphasized lower intensity resistance with relatively slow movements...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28713029/successive-odor-matching-and-non-matching-to-sample-in-rats-a-reversal-design
#13
Katherine Bruce, Katherine Dyer, Michael Mathews, Catharine Nealley, Tiffany Phasukkan, Ashley Prichard, Mark Galizio
There is a growing body of research on matching- and non-matching-to-sample (MTS, NMTS) relations with rats using olfactory stimuli; however, the specific characteristics of this relational control are unclear. In the current study we examine MTS and NMTS in rats with an automated olfactometer using a successive (go, no-go) procedure. Ten rats were trained to either match- or non-match-to-sample with common scents (apple, cinnamon, etc.) as olfactory stimuli. After matching or non-matching training with four odorants, rats were tested for transfer twice with four new odorants on each test...
July 13, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/28712784/effects-of-interventions-with-therapeutic-suits-clothing-on-impairments-and-functional-limitations-of-children-with-cerebral-palsy-a-systematic-review
#14
REVIEW
Kênnea M Almeida, Sérgio T Fonseca, Priscilla R P Figueiredo, Amanda A Aquino, Marisa C Mancini
BACKGROUND: Therapeutic suits or clothing whether associated with intensive protocols or not, became popular in the rehabilitation of children with cerebral palsy. Studies have reported positive effects of these suits on children's posture, balance, motor function and gait. A summary of current literature may help guide therapeutic actions. OBJECTIVE: To evaluate the available evidence on the effects of interventions based on the use of therapeutic suits in the treatment of impairments and functional limitations of children with cerebral palsy...
July 5, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28712529/dynamic-simulation-of-knee-joint-loading-during-gait-using-force-feedback-control-and-surrogate-contact-modelling
#15
Jonathan P Walter, Marcus G Pandy
The aim of this study was to perform multi-body, muscle-driven, forward-dynamics simulations of human gait using a 6-degree-of-freedom (6-DOF) model of the knee in tandem with a surrogate model of articular contact and force control. A forward-dynamics simulation incorporating position, velocity and contact force-feedback control (FFC) was used to track full-body motion capture data recorded for multiple trials of level walking and stair descent performed by two individuals with instrumented knee implants. Tibiofemoral contact force errors for FFC were compared against those obtained from a standard computed muscle control algorithm (CMC) with a 6-DOF knee contact model (CMC6); CMC with a 1-DOF translating hinge-knee model (CMC1); and static optimization with a 1-DOF translating hinge-knee model (SO)...
July 13, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28711049/quantitative-estimation-of-localization-errors-of-3d-transition-metal-pseudopotentials-in-diffusion-monte-carlo
#16
Allison L Dzubak, Jaron T Krogel, Fernando A Reboredo
The necessarily approximate evaluation of non-local pseudopotentials in diffusion Monte Carlo (DMC) introduces localization errors. We estimate these errors for two families of non-local pseudopotentials for the first-row transition metal atoms Sc-Zn using an extrapolation scheme and multideterminant wavefunctions. Sensitivities of the error in the DMC energies to the Jastrow factor are used to estimate the quality of two sets of pseudopotentials with respect to locality error reduction. The locality approximation and T-moves scheme are also compared for accuracy of total energies...
July 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28710207/comorbidities-complications-and-mortality-in-people-of-south-asian-ethnicity-with-type-1-diabetes-compared-with-other-ethnic-groups-a-systematic-review
#17
Komil N Sarwar, Phoebe Cliff, Ponnusamy Saravanan, Kamlesh Khunti, Krishnarajah Nirantharakumar, Parth Narendran
OBJECTIVE: The aim of this systematic review is to explore the association of South Asian (SA) ethnicity on comorbidities, microvascular and macrovascular complications and mortality compared with other ethnic groups in people with type 1 diabetes mellitus (T1DM). DESIGN: Systematic review. METHOD: A systematic literature search strategy was designed and carried out using Medline and Embase for full-text and abstract studies published in English from 1946 to February 2016...
July 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28709904/the-effects-of-gaze-stabilization-on-gait-parameters-in-individuals-with-parkinson-s-disease
#18
Rebecca J Reed-Jones, Douglas W Powell
The purpose of this study was to examine the effects of gaze fixation on head stabilization and gait during straight over ground walking in individuals with Parkinson's disease (PD). Eight individuals with PD (Age: 62.3±8.1years) volunteered for the study. Full body kinematic data were collected at 120Hz using a Vicon motion capture system. Two visual conditions were used to determine the effects of gaze fixation: FREE gaze and FIXED gaze. During FIXED gaze, participants were required to fixate on a still target 13meters ahead...
July 11, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28708734/t2-correction-in-dynamic-contrast-enhanced-magnetic-resonance-imaging-of-glioblastoma-from-a-half-dose-of-high-relaxivity-contrast-agent
#19
Silvano Filice, Girolamo Crisi, Gunter Erb
OBJECTIVE: The aim of this study was to evaluate the arterial input function (AIF) and tissue enhancement time curve (tissue function [TF]) obtained after the administration of a half-dose gadobenate dimeglumine (0.05-mmol/kg body weight [bw]) compared with a full dose (0.1-mmol/kg bw) of a standard-relaxivity contrast agent. METHODS: We enrolled 40 adult patients with glioblastoma in an interindividual comparative study. Patients were randomized to 1 of the 2 study arms: 20 patients received 0...
July 13, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28707543/pet-mri-knocking-on-the-doors-of-the-rich-and-famous
#20
Thomas Beyer, Marcus Hacker, Vicky Goh
Since 2010 the portfolio of PET-based imaging has been expanded by industry with the introduction of combined whole-body PET/MRI systems with the intent of merging PET-based molecular imaging with the strengths of MRI. PET/MRI has created a lot of hype in the scientific community but comparatively little traction in the clinic. The first years of whole-body PET/MRI were used to address inherent technical challenges, however, it is now time to make use of the full potential of this integrated imaging modality...
July 14, 2017: British Journal of Radiology
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