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JOURNAL ARTICLE
Amy Ming-Fang Yen, Chen-Yang Hsu, Ting-Yu Lin, Chiu-Wen Su, Han-Mo Chiu, Tony Hsiu-Hsi Chen, Sam Li-Sheng Chen
IMPORTANCE: Given a gradient relationship between fecal hemoglobin (f-Hb) concentration and colorectal neoplasia demonstrated previously, using f-Hb-guided interscreening interval has increasingly gained attention in population-based fecal immunological test (FIT), but it is very rare to address how to implement such a precision strategy and whether it can economize the use of FIT and colonoscopy. OBJECTIVE: To demonstrate the applicability of personalized colorectal cancer (CRC) screening with f-Hb-guided screening intervals to reduce the number of FITs and colonoscopy with as equivalent efficacy as universal biennial screening equivalent efficacy as universal biennial screening...
May 9, 2024: JAMA Oncology
#2
JOURNAL ARTICLE
Yao Liu, Yanan Li, Wenli Chen, Dandan Ming, Wenji Luo, Jiabi Liang
OBJECTIVE: Individual differences challenge the treatment of vancomycin, linezolid and voriconazole in severe infections. This study aimed to build a simple and economical method for simultaneous determination of the three antibiotics in human plasma by ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) and provided a reference for therapeutic drug monitoring (TDM) of infected patients. METHODS: The plasma samples were precipitated by acetonitrile and detected and separated on a shim-pack GIST C18 column following the gradient elution within 5 min...
May 9, 2024: Journal of Chromatographic Science
#3
JOURNAL ARTICLE
Tielong Wu
Nowadays, concurrent attention to economic development and ecological issues is becoming an important trend. In this paper, we measure the eco-efficiency of 285 Chinese cities from 2003 to 2019 using a non-radial directional distance function and the data envelopment analysis method, based on which we analyze the club convergence of cities' eco-efficiency using the logt test; we estimate the impact of open public data platforms on eco-efficiency and its convergence using a multi-period difference in difference model and panel-ordered logit model, respectively...
May 9, 2024: Environmental Science and Pollution Research International
#4
Katja C Heinz, Charlotte Beaudart, Damon Willems, Mickaël Hiligsmann
BACKGROUND: Treatment preference research can support shared and informed decision making for currently available atopic dermatitis (AD) treatments, and simultaneously guide research and development for future therapies. In this systematic literature review, we aimed to provide an overview of preferences for AD treatments. METHODS: This systematic literature review was conducted in the Medline and Embase (via Ovid) databases, supplemented by manual searching. Quantitative research published from 2010 to September 2023 that investigated preferences for AD treatments were included...
May 9, 2024: Patient
#5
JOURNAL ARTICLE
Yang Hu, Jian Cai, Yifu Song, Guoqiang Li, Yi Gong, Xingyu Jiang, Xiangming Tang, Keqiang Shao, Guang Gao
It is necessary to predict the critical transition of lake ecosystems due to their abrupt, non-linear effects on social-economic systems. Given the promising application of paleolimnological archives to tracking the historical changes of lake ecosystems, it is speculated that they can also record the lake's critical transition. We studied Lake Dali-Nor in the arid region of Inner Mongolia because of the profound shrinking the lake experienced between the 1300 s and the 1600 s. We reconstructed the succession of bacterial communities from a 140-cm-long sediment core at 4-cm intervals and detected the critical transition...
May 9, 2024: Microbial Ecology
#6
JOURNAL ARTICLE
M Alessandra Antonelli, Giorgia Marini
This paper investigates the role of institutional quality in explaining cross-regional variation in population health status in Italy. We first introduce a composite Regional Health Status Indicator summarizing life expectancy, mortality and morbidity data. Then, we study the empirical relationship between this indicator and a set of socioeconomic, health system and institutional controls at the Italian regional level over the period of 2011-2019. We find that institutional quality is a driver of population health...
May 9, 2024: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
#7
JOURNAL ARTICLE
Kalidhas Muthu, Sivakumar Ramamoorthy
Flood disasters are frequent natural disasters that occur annually during the monsoon season and significantly impact urban areas. This area is characterized by impermeable concrete surfaces, which increase runoff and are particularly susceptible to flooding. Therefore, this study aims to adopt Bi-variate statistical methods such as frequency ratio (FR) and weight of evidence (WOE) to map flood susceptibility in an urbanized watershed. The study area encompasses an urbanized watershed surrounding the Chennai Metropolitan area in southern India...
May 9, 2024: Environmental Monitoring and Assessment
#8
JOURNAL ARTICLE
Xiaojing Li, Qian Xu, Meijuan Qi, Jingwen Chen, Jiaxu Liu, Hong-Bin Xie, Ning He, Shaoyun Chen
To address the issue of high energy consumption associated with monoethanolamine (MEA) regeneration in the CO2 capture process, solid acid catalysts have been widely investigated due to their performance in accelerating carbamate decomposition. The recently discovered carbon nanotube (CNT) catalyst presents efficient catalytic activity for bicarbonate decomposition. In this paper, bifunctional catalysts SO4 2- /TiO2 -CNT (STC) were prepared, which could simultaneously catalyze carbamate and bicarbonate decomposition, and outstanding catalytic performance has been exhibited...
May 9, 2024: ACS Applied Materials & Interfaces
#9
REVIEW
Eduardo T Cánepa, Bruno G Berardino
Early-life adversities, whether prenatal or postnatal exposure, have been linked to adverse mental health outcomes later in life increasing the risk of several psychiatric disorders. Research on its neurobiological consequences demonstrated an association between exposure to adversities and persistent alterations in the structure, function, and connectivity of the brain. Consistent evidence supports the idea that regulation of gene expression through epigenetic mechanisms are involved in embedding the impact of early-life experiences in the genome and mediate between social environments and later behavioral phenotypes...
May 22, 2024: Biochemical Journal
#10
JOURNAL ARTICLE
H Blake, J Hassard, T Dulal-Arthur, M Wishart, S Roper, J Bourke, V Belt, C Bartle, N Pahl, S Leka, L Thomson
BACKGROUND: Mental ill health has a high economic impact on society and employers. National and international policy advocates line manager (LM) training in mental health as a key intervention, but little is known about employer training provisions. AIMS: To explore the prevalence and characteristics of organizations that offer LM training in mental health. METHODS: Secondary analysis of existing longitudinal anonymised organizational-level survey data derived from computer-assisted telephone interview surveys collected in four waves (2020:1900 firms, 2021:1551, 2022:1904, 2023:1902) in England, before, during and after a global pandemic...
May 9, 2024: Occupational Medicine
#11
JOURNAL ARTICLE
GDP-mannose pyrophosphorylase is an efficient target in Xanthomonas citri for citrus canker control.
André Vessoni Alexandrino, Mariana Pegrucci Barcelos, Leonardo Bruno Federico, Tamiris Garcia da Silva, Lúcia Bonci Cavalca, Carlos Henrique Alves de Moraes, Henrique Ferreira, Carlton Anthony Taft, Franklin Behlau, Carlos Henrique Tomich de Paula Silva, Maria Teresa Marques Novo-Mansur
UNLABELLED: Xanthomonas citri subsp. citri (Xcc) is a bacterium that causes citrus canker, an economically important disease that results in premature fruit drop and reduced yield of fresh fruit. In this study, we demonstrated the involvement of XanB, an enzyme with phosphomannose isomerase (PMI) and guanosine diphosphate-mannose pyrophosphorylase (GMP) activities, in Xcc pathogenicity. Additionally, we found that XanB inhibitors protect the host against Xcc infection. Besides being deficient in motility, biofilm production, and ultraviolet resistance, the xanB deletion mutant was unable to cause disease, whereas xanB complementation restored wild-type phenotypes...
May 9, 2024: Microbiology Spectrum
#12
JOURNAL ARTICLE
Anup Kumar Yadav, Dhananjay Yadav, Vipin Kumar, Subhasish Ray, Maya Shankar Singh
Herein, we report a viable protocol to access furo[3,2- c ]chromen-4-ones by engaging easily accessible 4-hydroxy coumarins as a three-atom CCO unit and thioamides as a C2 coupling partner, mediated by phenyliodine(III) diacetate (PIDA) at room temperature in a highly efficient and pot-/step-economical manner. This strategy not only avoids potential toxicity and tiresome workup conditions, but also features operational simplicity, a broad substrate scope, good functional group tolerance, high yields, easy scalability and exclusive selectivity...
May 9, 2024: Organic & Biomolecular Chemistry
#13
JOURNAL ARTICLE
Anna Rogozińska-Pawełczyk
OBJECTIVES: This study focuses on analyzing the impact of innovative human resource management practices (IHRMP) on knowledge worker burnout, and how organizational support and employee effort help explain this relationship in the context of the business services sector. To explore the problem, investigated whether IHRMP have a significant negative impact on employee burnout, and organizational support and employee effort mediate the negative impact of IHRMP on employee burnout. MATERIAL AND METHODS: A survey was conducted, collected using the computer assisted web interview method on 1000 knowledge workers employed at business services sector (BSS) organizations in Poland...
May 8, 2024: International Journal of Occupational Medicine and Environmental Health
#14
JOURNAL ARTICLE
Kimmo Suokas, Maija Lindgren, Mika Gissler, Emmi Liukko, Laura Schildt, Raimo K R Salokangas, Päivi Rissanen, Tapio Gauffin, Petri Näätänen, Minna Holm, Jaana Suvisaari
BACKGROUND: Timely outpatient follow-up and readmission after discharge are common quality indicators in psychiatric care, but their association varies in previous research. We aimed to examine whether the impact of outpatient follow-up and other factors on readmission risk evolves over time in people with non-affective psychotic disorder (NAP). METHODS: The Finnish Quality of Care Register includes all people diagnosed with NAP since January 2010. Here, we followed patients with a hospital discharge between 2017 and 2021 until readmission, death, or up to 365 days...
May 9, 2024: Psychological Medicine
#15
JOURNAL ARTICLE
Jaehyuk Jung, Kyeong-Eun Lee, Seri Hong, Jae Bum Park, Inchul Jeong
BACKGROUND: While unemployment is known to increase the risk of suicide, its cumulative effect remains underexplored. This study investigates how unemployment affects suicide mortality and whether the effect varies based on the number of unemployment spells using two years of nationwide data. METHODS: Using the data from the National Statistical Office and Employment Insurance Database for 2018 and 2019, we identified an average of 2365 cases of suicide over two years among 7...
May 9, 2024: Psychological Medicine
#16
JOURNAL ARTICLE
Yoshiko Atsuta, Helen Baldomero, Daniel Neumann, Anna Sureda, Jakob D DeVos, Minako Iida, Amado Karduss, Duncan Purtill, Alaa M Elhaddad, Nosa G Bazuaye, Carmem Bonfim, Rafael De la Camara, Naeem A Chaudhri, Fabio Ciceri, Cinthya Correa, Cristobal Frutos, Sebastian Galeano, Laurent Garderet, Oscar Gonzalez-Ramella, Raffaella Greco, Nada Hamad, Mette D Hazenberg, Mary M Horowitz, Krzysztof Kalwak, Bor-Sheng Ko, Yoshihisa Kodera, Mickey Bc Koh, Kaiyan Liu, Donal P McLornan, Joon Ho Moon, Benedicte Neven, Shinichiro Okamoto, Marcelo C Pasquini, Jakob R Passweg, Kristjan Paulson, Damiano Rondelli, Annalisa Ruggeri, Adriana Seber, John A Snowden, Alok Srivastava, Jeff Szer, Daniel Weisdorf, Nina Worel, Hildegard Greinix, Wael Saber, Mahmoud Aljurf, Dietger Niederwieser
Promoting access to and excellence in hematopoietic cell transplantation (HCT) by collecting and disseminating data on global HCT activities is one of the principal activities of the Worldwide Network for Blood and Marrow Transplantation, a non-Governmental organization in working relations with the World Health Organization. HCT activities are recorded annually by member societies, national registries and individual centers including indication, donor type (allogeneic/autologous), donor match and stem cell source (bone marrow/peripheral blood stem cells/cord blood)...
May 9, 2024: Haematologica
#17
JOURNAL ARTICLE
Trafford R Crump, Gunnar Siljedal, Ezekiel Weis, Alex Ragan, Jason M Sutherland
This paper examines the contentious issue of using contracted surgical facilities (CSFs) for scheduled eye surgeries within Canada's publicly funded healthcare system. Despite the debate over the use of CSFs, there is a stark lack of Canadian-focused empirical evidence to guide policy decisions. This paper uses the Organisation for Economic Co-operation and Development's healthcare system performance conceptual model - access, quality and cost/expenditures - as a framework to explore the debates surrounding CSFs...
February 2024: Healthcare Policy
#18
JOURNAL ARTICLE
Zeeshan Ali Lashari, Bashirul Haq, Dhafer Al Shehri, Amir Al Ahmed, Najeebullah Lashari, Ehsan Zaman, S M Zakir Hossain
The transition of the global energy market towards an environment-friendly, sustainable society requires a profound transformation from fossil fuel to zero carbon emission fuel. To cope with this goal production of renewable energy is accelerating worldwide. Hydrogen is a clean energy carrier, due to its clean combustion and abundance. Nonetheless, its storage is a critical challenge to its success. Hydrogen must be stored long after being produced and transported to a storage site. Physical hydrogen storage (PHS) is vital among hydrogen storage modes, and its shortcoming needs to overcome for its successful and economic benefits...
May 9, 2024: Chemistry, An Asian Journal
#19
JOURNAL ARTICLE
Keshia R De Guzman, Anthony C Smith, Centaine L Snoswell
AIM: To identify and quantify general practitioner (GP) preferences related to service attributes of clinical consultations, including telehealth consultations, in Australia. BACKGROUND: GPs have been increasingly using telehealth to deliver patient care since the onset of the 2019 coronavirus disease (COVID-19) pandemic. GP preferences for telehealth service models will play an important role in the uptake and sustainability of telehealth services post-pandemic...
May 9, 2024: Primary Health Care Research & Development
#20
JOURNAL ARTICLE
Jingyi Ma, Kimberly Eadie, Ahmed Fahal, Annelies Verbon, Wendy W J van de Sande
BACKGROUND: in vitro susceptibility testing for the non-sporulating fungus Madurella mycetomatis is performed with a hyphal suspension as starting inoculum and a viability dye for endpoint reading. Here we compared the performance of four different viability dyes for their use in in vitro susceptibility testing of M. mycetomatis. METHODS: To compare the reproducibility and the agreement between the viability dyes 2,3-bis-(2-methoxy-4-nitro-5-sulfphenyl)-2H-tetrazolium-5-carboxanilide salt (XTT), resazurin, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium salt (MTS) and luciferin, the in vitro susceptibilities of 14 genetically diverse M...
May 9, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
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