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skull base tumour

Venkatraman Bhat, Jenna Devere, Athira Ramakrishanan, Moni A Kuriakose
A case of malignant cutaneous lesion of the face diagnosed initially as sebaceous carcinoma, subsequently proven to be squamous cell carcinoma is presented. Patient was initially evaluated at an outside institution by computed tomography, which indicated extension of lesion to the maxillary sinus. Patient underwent local resection. Further imaging by magnetic resonance imaging was done for recurrent tumour. Examination revealed extensive, large volume, perineural extension of the disease via infraorbital nerve to the cavernous sinus...
September 2016: Journal of Maxillofacial and Oral Surgery
N-X Bonne, F Dubrulle, M Risoud, C Vincent
The surgical management of skull base lesions is difficult due to the complex anatomy of the region and the intimate relations between the lesion and adjacent nerves and vessels. Minimally invasive approaches are increasingly used in skull base surgery to ensure an optimal functional prognosis. Three-dimensional (3D) computed tomography (CT) reconstruction facilitates surgical planning by visualizing the anatomical relations of the lesions in all planes (arteries, veins, nerves, inner ear) and simulation of the surgical approach in the operating position...
October 5, 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
Alvaro Otero-Rodriguez, Maria Dolores Tabernero, Maria Cristina Munoz-Martin, Pablo Sousa, Alberto Orfao, Daniel Pascual-Argente, Maria Gonzalez-Tablas, Laura Ruiz-Martin
BACKGROUND: Since 1957, Simpson grading system is considered a predictive system for meningiomas recurrences. However, since then, there has been a great development of surgical equipment and neurosurgical technique, so the re-evaluation of this grading system should be considered. This study aims to assess if the recurrence rates and recurrence-free survivals (RFS) are different after Simpson grades I, II, and III resections in World Health Organization (WHO) grade I meningiomas METHOD: We retrospectively reviewed the data of patients who underwent surgical treatment of WHO grade I meningiomas located in convexity (group 1), falx/parasagittal (group 2), skull base, and tentorium (group 3) between June 1991 and December 2011...
September 13, 2016: World Neurosurgery
Eleni Daniel, Robert Jones, Matthew Bull, John Newell-Price
INTRODUCTION: Patients with SDHx mutations need long-term radiological surveillance for the development of paragangliomas and phaeochromocytomas, but no longitudinal data exist. We assessed the performance of rapid-sequence non-contrast magnetic resonance imaging (MRI) in the long-term monitoring of patients with SDHx mutations. METHODS: Retrospective study between 2005-2015 at a University Hospital and regional endocrine genetics referral center. Clinical and imaging data of forty-seven patients with SDHx mutations [SDHB (36), SDHC (6), SDHD (5)] who had surveillance for detection of paragangliomas by rapid-sequence non-contrast MRI (base of skull to pubic symphysis) were collected...
September 15, 2016: European Journal of Endocrinology
Soroush Larjani, Eric Monteiro, Ian Witterick, Allan Vescan, Gelareh Zadeh, Fred Gentili, David P Goldstein, John R de Almeida
BACKGROUND: The Skull Base Inventory (SBI) was developed to assess the quality of life of patients undergoing endoscopic or open approaches for anterior and central skull base pathologies. In this study, we sought to establish the discriminative and evaluative properties for this instrument. METHODS: The SBI was administered in a cross-sectional fashion to patients who previously had skull base surgery after treatment and then again 2 weeks after completing the instrument...
2016: Journal of Otolaryngology—Head & Neck Surgery
Veena Sheshadri, Suparna Bharadwaj, B A Chandramouli
BACKGROUND AND AIMS: Intra-operative identification and preservation of extraocular motor nerves is one of the main goals of surgeries for skull base tumours and this is done by monitoring the extraocular movement (EOM). Intra-operative electromyographic monitoring has been reported, but it is a complex and skilful process. Electrooculography (EOG) is a simple and reliable technique for monitoring EOMs. We aimed to assess the utility of EOG monitoring in preventing extraocular motor nerve dysfunction during skull base surgeries...
August 2016: Indian Journal of Anaesthesia
Samuel J C Fishpool, Anthony Amato-Watkins, Caroline Hayhurst
The objective is to assess whether free middle turbinate (FMT) graft reconstruction, after endoscopic endonasal pituitary surgery, combines an acceptably low post-operative cerebrospinal fluid (CSF) leak rate with acceptable rhinological morbidity. This study identified 50 patients who underwent endoscopic endonasal pituitary surgery by the senior author in our teaching hospital between May 2011 and June 2012. FMT graft reconstruction was used in 32 cases. 18 patients were judged pre-operatively as not suitable for FMT reconstruction according to a novel skull base reconstructive algorithm...
September 1, 2016: European Archives of Oto-rhino-laryngology
C R Wirtz
Intraoperative navigation systems are widely used in ENT, oral and maxillofacial, and neurosurgery. The benefits of such systems have been demonstrated in various applications, including intracranial and skull base surgery. Intraoperative shift, "brain shift" and changes in anatomy caused by the surgical procedure itself impair the accuracy of navigation and represent factors limiting its application, particularly in glioma and metastatic brain surgery. For this reason, intraoperative imaging was incorporated into neurosurgery...
September 2016: HNO
N Phillips, P Nix
BACKGROUND: Endoscopic endonasal surgery to access the anterior skull base has evolved in many centres worldwide and provides a minimally invasive alternative, with better patient experience, to open techniques. METHOD: We present a basic approach to a midline lesion that is the fundamental starting point for wider access to the skull base. CONCLUSION: The nuances of this technique illustrated here have been developed in many centres to provide a safe procedure that has a low incidence of complications and excellent potential...
October 2016: Acta Neurochirurgica
İhsan Doğan, Gökmen Kahiloğullari, Haydar Sekmen, Ümit Eroğlu, Onur Özgüral, Ağahan Ünlü
AIM: The objective of this study was to report our clinical experience, surgical treatment algorithm and technique in reconstruction of uncomplicated and small-size calvarial defects by performing autolog split-bone grafting technique on anatomical findings and patients outcome. MATERIAL AND METHODS: In thirty-six patients (aged between 28 and 125 months; median age, 68.75 months, minimum follow-up 14 months), following the resection of pathological skull region, the defective calvarial zone without bone (area, 3...
March 28, 2016: Turkish Neurosurgery
Thomas H Newman, Geoffrey A Tipper, Zakier Hussain
Sinonasal adenocarcinomas are rare, locally invasive tumours. In this case the symptomatic profile was unusual and the diagnosis was missed at the primary care stage. Interestingly this would be the first documented case with an absent ipsilateral olfactory bulb. A 55-year old male presented with symptoms of behavioural change and mild headaches. He was later found to have a large Sinonasal adenocarcinoma which penetrated the skull base. This was treated by a combined craniotomy and endonasal approach. Sinonasal adenocarcinomas are unusual tumours and further research is required in order to clarify management strategies and prognosis...
2016: Journal of Surgical Case Reports
C C Yong, A Soni-Jaiswal, J J Homer
BACKGROUND: The subcranial approach is a modification of traditional craniofacial resection. It provides similar broad access to the anterior skull base, but with lower mortality and morbidity. It has been the surgical technique of choice at our institution since 2006 for treating advanced stage sinonasal tumours (American Joint Committee on Cancer stage III or above). This paper reports our experience and outcomes. METHOD AND RESULTS: Eighteen patients underwent subcranial craniofacial resection over a seven-year period, this being combined with a second adjunctive procedure in 89 per cent of cases...
August 2016: Journal of Laryngology and Otology
V F Antoniv, I V Koval', V I Popadyuk, T V Antoniv, V M Aksenov
The objective of the present work was to describe the poorly known history of the development of the nomenclature of glomus tumours (chemodectomas) of the base of the skull, elucidate etiology and pathogenesis of these neoplasms. The authors present a chronological table illustrating the progress of etiological and pathogenetic studies as well as the surgical treatment of the tumours. The results of analysis and discussion of the controversial issues of the nomenclature are reported.
2016: Vestnik Otorinolaringologii
Geoffrey Mortuaire, Xavier Leroy, Claire Vandenhende-Szymanski, Dominique Chevalier, Anne-Sophie Thisse
Endoscopic sinus surgery (ESS) is considered as a valid option in the management of nasal adenocarcinoma (ADC). Comparative studies with open approaches are still required. A monocentric retrospective study was carried out from May 2002 to December 2013, including 43 patients with intestinal-type adenocarcinoma of the ethmoid sinus. Non-resectable tumours or recurrences were excluded. Before 2008, open approach with lateral rhinotomy (LR) was performed as the gold standard of treatment. From 2008, ESS was systematically used as a first-line option as long as a complete resection was achievable...
June 30, 2016: European Archives of Oto-rhino-laryngology
Marco Krengli, Arturo Poletti, Eleonora Ferrara, Piero Fossati
AIM: The aim of this study is to review the clinical series in which tumour seeding was reported after skull base surgery for chordomas. BACKGROUND: The occurrence of implantation of cancer cells during surgical procedures for the removal of chordoma is a rare event described by a number of authors in a few patient series and case reports. MATERIALS AND METHODS: Literature search was performed by PubMed and Scopus by using the words "surgical tumour seeding, tumour implantation, surgical pathway recurrence, skull base chordoma, and clivus chordoma"...
July 2016: Reports of Practical Oncology and Radiotherapy
Arturo Mario Poletti, Siba Prasad Dubey, Giovanni Colombo, Giovanni Cugini, Antonio Mazzoni
AIM: To define a better treatment of sporadic endolymphatic sac tumours (ELST) analysing our experience and literature available data. BACKGROUND: ELST can arise as sporadic case (rare) or as a part of von Hippel-Lindau (VHL) disease. It is a low grade malignancy with local spread by continuity. MATERIALS AND METHODS: we described our experience with 7 cases with up to date follow up. RESULTS: Five cases were free of disease after first surgical procedure...
July 2016: Reports of Practical Oncology and Radiotherapy
Vittoria Colia, Salvatore Provenzano, Nadia Hindi, Paolo G Casali, Silvia Stacchiotti
This review highlights the data currently available on the activity of systemic therapy in chondrosarcoma, chordoma, giant cell tumour of the bone (GCTB) and solitary fibrous tumour, i.e., four rare sarcomas amongst mesenchymal malignancy arising from the skull base.
July 2016: Reports of Practical Oncology and Radiotherapy
Piero Fossati, Andrea Vavassori, Letizia Deantonio, Eleonora Ferrara, Marco Krengli, Roberto Orecchia
An extremely large variety of benign and malignant tumours occur at skull base; these tumour lesions are in the proximity to structures deputed to relevant physiologic functions, limiting extensive surgical approaches to this body district. Most recent progresses of surgery and radiotherapy have allowed to improve local control with acceptable rates of side effects. Various photon radiotherapy techniques are employed, including 3-dimensional conformal radiotherapy, intensity modulated radiotherapy (IMRT), stereotactic radiotherapy (SRT) and brachytherapy that is manly limited to the treatment of primary or recurrent nasopharyngeal carcinoma...
July 2016: Reports of Practical Oncology and Radiotherapy
Antonio Mazzoni, Marco Krengli
Surgery has evolved greatly over the last decades thanks to the more sophisticated and conservative surgical approaches and also thanks to the progress of diagnostic imaging. An added value is represented by the increased experience of the professionals and the close multidisciplinarity of the procedures including neurosurgeons, otolaryngologists and maxillo-facial surgeons. One of the most recent developments is the endoscopic surgery allowing for more conservative and cosmetically satisfactory outcomes. Radiation therapy has greatly changed over the last decades thanks to the technology advances related both to the availability of new imaging modalities and techniques of radiation delivery...
July 2016: Reports of Practical Oncology and Radiotherapy
Stefanie Catherine Thust, Tarek Yousry
The skull base is a highly complex and difficult to access anatomical region, which constitutes a relatively common site for neoplasms. Imaging plays a central role in establishing the differential diagnosis, to determine the anatomic tumour spread and for operative planning. All skull base imaging should be performed using thin-section multiplanar imaging, whereby CT and MRI can be considered complimentary. An interdisciplinary team approach is central to improve the outcome of these challenging tumours.
July 2016: Reports of Practical Oncology and Radiotherapy
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