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Neurogenic bladder disability

Meheroz H Rabadi, Christopher E Aston
BACKGROUND: Examining factors that increase risk of death in veterans with multiple sclerosis (MS) may help reduce MS-related mortality. We sought to determine predictors of mortality in veterans with MS attending an outpatient clinic. METHODS: Review of electronic medical records of 226 veterans with MS regularly followed up from January 1, 2000, through December 31, 2014. RESULTS: Mortality at the end of the 15-year study period was 14%...
September 2017: International Journal of MS Care
N Brownrigg, L H Braga, M Rickard, F Farrokhyar, B Easterbrook, A Dekirmendjian, K Jegatheeswaran, J DeMaria, A J Lorenzo
INTRODUCTION: Bladder and bowel dysfunction (BBD) can negatively impact the quality of life (QoL) of children. Urotherapy is an accepted treatment option for BBD; however, literature that examines the impact of management options on QoL in this population is scarce. OBJECTIVE: To determine whether a bladder training video (BTV) is non-inferior to standard urotherapy (SU) in improving QoL in children with BBD. METHODS: Children aged 5-10 years and who scored ≥11 on the Vancouver Non-Neurogenic Lower Urinary Tract Dysfunction/Dysfunctional Elimination Syndrome Questionnaire (NLUTD/DES) were recruited from a pediatric tertiary care center...
August 2017: Journal of Pediatric Urology
Isaac D Palma-Zamora, Humphrey O Atiemo
Neurogenic bladder is a chronic and disabling condition associated with multiple comorbidities and a widespread economic impact. Literature on cost of care and resource utilization is sparse and heterogeneous. Nonstandardized approaches, impact perspectives, and types of costs are used to describe the economic implications of neurogenic bladder. The financial toll is difficult to ascertain due to indirect and intangible costs exacerbated by the underlying disability. Health resource utilization based on clinical manifestations of neurogenic bladder may serve as an alternative measure...
August 2017: Urologic Clinics of North America
J Bremer, B Domurath, R Böthig, A Kaufmann, V Geng
BACKGROUND: Using the CE mark of therapeutic appliances is, on its own, not sufficient enough for their appropriate and effective application. In order to treat the patient successfully, not jeopardizing the success of the treatment, medical quality criteria for therapeutic appliances care are necessary to acceptably compensate for a patient's disabilities. OBJECTIVES: Medical quality criteria are formulated for the most frequently used urological aids and devices, considering hygienic requirements, international literature and the practical experience of physicians and nurses with regard to the care of patients with neurogenic urinary bladder dysfunction...
July 13, 2017: Der Urologe. Ausg. A
Sanjeev Rastogi
INTRODUCTION: Neurogenic bladder is a common urological condition among elderly. It results in incontinence or retention of the urine depending on the synergy of bladder smooth muscles and urethral sphincter. There can also be a condition where retention causes overflow incontinence. Retention of urine in this condition is caused by relative lack of contractility of bladder smooth muscles in response to the stretch reflex. As a result, there is no urge and therefore the bladder remains over-distended causing retention of urine...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
Juan Francisco Vázquez-Costa, Salvador Arlandis, David Hervas, Esther Martínez-Cuenca, Fernando Cardona, Jordi Pérez-Tur, Enrique Broseta, Teresa Sevilla
INTRODUCTION: Lower urinary tract symptoms (LUTS) are frequent in motor neuron disease (MND) patients, but clinical factors related to them are unknown. We describe differences in LUTS among MND phenotypes and their relationship with other clinical characteristics, including prognosis. METHODS: For this study, we collected clinical data of a previously published cohort of patients diagnosed with classical amyotrophic lateral sclerosis (cALS), progressive muscular atrophy (PMA) or primary lateral sclerosis (PLS) with and without LUTS...
July 15, 2017: Journal of the Neurological Sciences
Rebecca Haddad, Alix Verrando, Claire Hentzen, Laura Weglinski, Frédérique Le Breton, Delphine Verollet, Gérard Amarenco
OBJECTIVE: Self-clean intermittent catheterization (CIC) is a part of the arsenal of treatment strategies of neurogenic bladder (1). The acquisition of this technique depends on environment and parameters related to the patients, that can be measured by the FIM score (Functional Independence Measure), validated in various neurological populations (2). The objective of this study is to determine whether disability, as measured by the FIM, is predictive of the acquisition and the retention of CIC...
September 2016: Annals of Physical and Rehabilitation Medicine
A J Wright, O Fletcher, D Scrutton, G Baird
INTRODUCTION: The attainment of continence is an important milestone in all children, including those with disability. OBJECTIVE: To describe the age of bladder and bowel continence in children with bilateral cerebral palsy (BCP), and the association with intellectual impairment (II) and severity of motor disability. PATIENTS AND METHODS: The parents of 346 children with BCP were interviewed as part of a population-based prospective study of the children at 3, 7, and 17 years of age...
December 2016: Journal of Pediatric Urology
Eugenia Fragalà, Giorgio Ivan Russo, Alessandro Di Rosa, Raimondo Giardina, Salvatore Privitera, Vincenzo Favilla, Francesco Patti, Blayne Welk, Sebastiano Cimino, Tommaso Castelli, Giuseppe Morgia
PURPOSE: To determine the relationship between the neurogenic bladder symptoms score (NBSS) and urodynamic examination in patients affected by multiple sclerosis (MS) and related lower urinary tract dysfunction (LUTD). METHODS: We recruited 122 consecutive patients with MS in remission and LUTD from January 2011 to September 2013 who underwent their first urodynamic examination. Neurological impairment was assessed using the Expanded Disability Status Scale (EDSS) and bladder symptoms were studied with the NBSS...
December 2015: International Neurourology Journal
Andrea Nevedal, Anna L Kratz, Denise G Tate
PURPOSE: Neurogenic bladder and bowel (NBB) is a chronic condition hindering the functioning and quality of life (QOL) of people with spinal cord injury (SCI). NBB research has focused on men with SCI leaving unanswered questions about women's experiences of living with NBB. The purpose of this study was to identify and describe women's experiences of living with SCI and NBB. METHOD: Secondary analysis of semi-structured interviews from a larger qualitative study of women with SCI (N = 50) was carried out...
2016: Disability and Rehabilitation
Anne P Cameron, Gianna M Rodriguez, Amy Gursky, Chang He, J Quentin Clemens, John T Stoffel
PURPOSE: Patients with neurological conditions often experience severe debilitating lower urinary and bowel dysfunction in addition to the physical disabilities. However, only the bladder has received the attention of medical providers with neurogenic bowel being poorly understood and characterized. MATERIALS AND METHODS: This is a cross-sectional analysis of a prospective institutional neurogenic bladder database from 2010 to 2013. RESULTS: Of the 175 patients 60...
November 2015: Journal of Urology
Johann Hofereiter, Matthew D Smith, Jai Seth, Katarina Ivana Tudor, Zoe Fox, Anton Emmanuel, Elaine Murphy, Robin H Lachmann, Jalesh Panicker
BACKGROUND: X-linked adrenoleukodystrophy (X-ALD) is a disorder caused by mutations in the ABCD1 gene. The commonest phenotype of X-ALD is adrenomyeloneuropathy (AMN), which is characterised by involvement of the spinal cord and peripheral nerves. The aim of this study was to evaluate bladder and bowel symptoms in men with AMN and female X-ALD carriers. METHODS: In this cross-sectional study, patients with confirmed mutation of the ABCD1 gene attending a tertiary care service were approached about bladder and bowel complaints and completed the Urinary Symptom Profile (USP), Qualiveen Short Form (SF-Qualiveen), International Prostate Symptom Score (IPSS) and Neurogenic Bowel Dysfunction (NBD) questionnaires...
2015: JIMD Reports
Kemal Nas, Levent Yazmalar, Volkan Şah, Abdulkadir Aydın, Kadriye Öneş
Spinal cord injury (SCI) is the injury of the spinal cord from the foramen magnum to the cauda equina which occurs as a result of compulsion, incision or contusion. The most common causes of SCI in the world are traffic accidents, gunshot injuries, knife injuries, falls and sports injuries. There is a strong relationship between functional status and whether the injury is complete or not complete, as well as the level of the injury. The results of SCI bring not only damage to independence and physical function, but also include many complications from the injury...
January 18, 2015: World Journal of Orthopedics
B Tsang, L Stothers, A Macnab, D Lazare, M Nigro
AIMS: Validated questionnaires are increasingly the preferred method used to obtain historical information. Specialized questionnaires exist validated for patients with neurogenic disease including neurogenic bladder. Those currently available are systematically reviewed and their potential for clinical and research use are described. METHODS: A systematic search via Medline and PubMed using the key terms questionnaire(s) crossed with Multiple Sclerosis (MS) and Spinal Cord Injury (SCI) for the years 1946 to January 22, 2014 inclusive...
March 2016: Neurourology and Urodynamics
Shaoping Hou, Alexander G Rabchevsky
Spinal cord injury (SCI) results not only in motor and sensory deficits but also in autonomic dysfunctions. The disruption of connections between higher brain centers and the spinal cord, or the impaired autonomic nervous system itself, manifests a broad range of autonomic abnormalities. This includes compromised cardiovascular, respiratory, urinary, gastrointestinal, thermoregulatory, and sexual activities. These disabilities evoke potentially life-threatening symptoms that severely interfere with the daily living of those with SCI...
October 2014: Comprehensive Physiology
E Fragalà, G I Russo, A Di Rosa, R Giardina, S Privitera, V Favilla, T Castelli, M Chisari, A Caramma, F Patti, S Cimino, G Morgia
BACKGROUND AND PURPOSE: Sexual dysfunction (SD) is prevalent in multiple sclerosis (MS) patients and affects quality of life. Furthermore, lower urinary tract dysfunction (LUTD) is common in MS patients. Our aim was to determine the relationship between urodynamic findings and SD in a cohort of MS patients with LUTD. METHODS: From January 2011 to September 2013, 135 consecutive patients with MS in remission phase and LUTD underwent a first urodynamic examination, according to the International Continence Society criteria...
March 2015: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
Aaron Saguil, Shawn Kane, Edwin Farnell
Multiple sclerosis (MS) is the most common permanently disabling disorder of the central nervous system in young adults. Relapsing remitting MS is the most common type, and typical symptoms include sensory disturbances, Lhermitte sign, motor weakness, optic neuritis, impaired coordination, and fatigue. The course of disease is highly variable. The diagnosis is clinical and involves two neurologic deficits or objective attacks separated in time and space. Magnetic resonance imaging is helpful in confirming the diagnosis and excluding mimics...
November 1, 2014: American Family Physician
Rosalie M Grivell, Chad Andersen, Jodie M Dodd
BACKGROUND: Spina bifida is a fetal neural tube defect (NTD), which may be diagnosed in utero and is compatible with life postnatally, albeit often with significant disability and morbidity. Although postnatal repair is possible, with increasing in utero diagnosis with ultrasound, the condition has been treated during pregnancy (prenatal repair) with the aim of decreased morbidity for the child. The procedure that is performed during pregnancy does have potential morbidities for the mother, as it involves maternal surgery to access the fetus...
October 28, 2014: Cochrane Database of Systematic Reviews
Nobuhiko Okamoto, Fuyuki Miya, Tatsuhiko Tsunoda, Keiko Yanagihara, Mitsuhiro Kato, Shinji Saitoh, Mami Yamasaki, Yonehiro Kanemura, Kenjiro Kosaki
Kinesins are a large superfamily of molecular motors. They move along microtubule filaments and are powered by the hydrolysis of ATP. This transport system is essential for neuronal function and survival. KIF1A belongs to the kinesin 3 family and involves in the anterograde transport of synaptic vesicle precursors along axons. Several studies confirmed that KIF1A mutations cause spastic paraplegia and sensory neuropathy in an autosomal-recessive fashion. A missense mutation in the KIF1A gene (p.Thr99Met) has been reported in a patient with intellectual disability (ID), axial hypotonia and peripheral spasticity...
November 2014: Journal of Human Genetics
L Gaspard, B Tombal, R-J Opsomer, Y Castille, V Van Pesch, C Detrembleur
AIM: This randomized controlled trial compare the efficacy of pelvic floor muscle training vs. transcutaneous posterior tibial nerve stimulation. PATIENTS AND METHODS: Inclusion criteria were EDSS score<7 and presence of lower urinary tract symptoms. Exclusion criteria were multiple sclerosis relapse during the study, active urinary tract infection and pregnancy. The primary outcome was quality of life (SF-Qualiveen questionnaire). Secondary outcomes included overactive bladder (USP questionnaire) score and frequency of urgency episodes (3-day bladder diary)...
September 2014: Progrès en Urologie
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