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Neurogenic bladder disability

Rebecca Haddad, Alix Verrando, Claire Hentzen, Laura Weglinski, Frédérique Le Breton, Delphine Verollet, Gérard Amarenco
OBJECTIVE: Self-clean intermittent catheterization (CIC) is a part of the arsenal of treatment strategies of neurogenic bladder (1). The acquisition of this technique depends on environment and parameters related to the patients, that can be measured by the FIM score (Functional Independence Measure), validated in various neurological populations (2). The objective of this study is to determine whether disability, as measured by the FIM, is predictive of the acquisition and the retention of CIC...
September 2016: Annals of Physical and Rehabilitation Medicine
A J Wright, O Fletcher, D Scrutton, G Baird
INTRODUCTION: The attainment of continence is an important milestone in all children, including those with disability. OBJECTIVE: To describe the age of bladder and bowel continence in children with bilateral cerebral palsy (BCP), and the association with intellectual impairment (II) and severity of motor disability. PATIENTS AND METHODS: The parents of 346 children with BCP were interviewed as part of a population-based prospective study of the children at 3, 7, and 17 years of age...
December 2016: Journal of Pediatric Urology
Eugenia Fragalà, Giorgio Ivan Russo, Alessandro Di Rosa, Raimondo Giardina, Salvatore Privitera, Vincenzo Favilla, Francesco Patti, Blayne Welk, Sebastiano Cimino, Tommaso Castelli, Giuseppe Morgia
PURPOSE: To determine the relationship between the neurogenic bladder symptoms score (NBSS) and urodynamic examination in patients affected by multiple sclerosis (MS) and related lower urinary tract dysfunction (LUTD). METHODS: We recruited 122 consecutive patients with MS in remission and LUTD from January 2011 to September 2013 who underwent their first urodynamic examination. Neurological impairment was assessed using the Expanded Disability Status Scale (EDSS) and bladder symptoms were studied with the NBSS...
December 2015: International Neurourology Journal
Andrea Nevedal, Anna L Kratz, Denise G Tate
PURPOSE: Neurogenic bladder and bowel (NBB) is a chronic condition hindering the functioning and quality of life (QOL) of people with spinal cord injury (SCI). NBB research has focused on men with SCI leaving unanswered questions about women's experiences of living with NBB. The purpose of this study was to identify and describe women's experiences of living with SCI and NBB. METHOD: Secondary analysis of semi-structured interviews from a larger qualitative study of women with SCI (N = 50) was carried out...
2016: Disability and Rehabilitation
Anne P Cameron, Gianna M Rodriguez, Amy Gursky, Chang He, J Quentin Clemens, John T Stoffel
PURPOSE: Patients with neurological conditions often experience severe debilitating lower urinary and bowel dysfunction in addition to the physical disabilities. However, only the bladder has received the attention of medical providers with neurogenic bowel being poorly understood and characterized. MATERIALS AND METHODS: This is a cross-sectional analysis of a prospective institutional neurogenic bladder database from 2010 to 2013. RESULTS: Of the 175 patients 60...
November 2015: Journal of Urology
Johann Hofereiter, Matthew D Smith, Jai Seth, Katarina Ivana Tudor, Zoe Fox, Anton Emmanuel, Elaine Murphy, Robin H Lachmann, Jalesh Panicker
BACKGROUND: X-linked adrenoleukodystrophy (X-ALD) is a disorder caused by mutations in the ABCD1 gene. The commonest phenotype of X-ALD is adrenomyeloneuropathy (AMN), which is characterised by involvement of the spinal cord and peripheral nerves. The aim of this study was to evaluate bladder and bowel symptoms in men with AMN and female X-ALD carriers. METHODS: In this cross-sectional study, patients with confirmed mutation of the ABCD1 gene attending a tertiary care service were approached about bladder and bowel complaints and completed the Urinary Symptom Profile (USP), Qualiveen Short Form (SF-Qualiveen), International Prostate Symptom Score (IPSS) and Neurogenic Bowel Dysfunction (NBD) questionnaires...
2015: JIMD Reports
Kemal Nas, Levent Yazmalar, Volkan Şah, Abdulkadir Aydın, Kadriye Öneş
Spinal cord injury (SCI) is the injury of the spinal cord from the foramen magnum to the cauda equina which occurs as a result of compulsion, incision or contusion. The most common causes of SCI in the world are traffic accidents, gunshot injuries, knife injuries, falls and sports injuries. There is a strong relationship between functional status and whether the injury is complete or not complete, as well as the level of the injury. The results of SCI bring not only damage to independence and physical function, but also include many complications from the injury...
January 18, 2015: World Journal of Orthopedics
B Tsang, L Stothers, A Macnab, D Lazare, M Nigro
AIMS: Validated questionnaires are increasingly the preferred method used to obtain historical information. Specialized questionnaires exist validated for patients with neurogenic disease including neurogenic bladder. Those currently available are systematically reviewed and their potential for clinical and research use are described. METHODS: A systematic search via Medline and PubMed using the key terms questionnaire(s) crossed with Multiple Sclerosis (MS) and Spinal Cord Injury (SCI) for the years 1946 to January 22, 2014 inclusive...
March 2016: Neurourology and Urodynamics
Shaoping Hou, Alexander G Rabchevsky
Spinal cord injury (SCI) results not only in motor and sensory deficits but also in autonomic dysfunctions. The disruption of connections between higher brain centers and the spinal cord, or the impaired autonomic nervous system itself, manifests a broad range of autonomic abnormalities. This includes compromised cardiovascular, respiratory, urinary, gastrointestinal, thermoregulatory, and sexual activities. These disabilities evoke potentially life-threatening symptoms that severely interfere with the daily living of those with SCI...
October 2014: Comprehensive Physiology
E Fragalà, G I Russo, A Di Rosa, R Giardina, S Privitera, V Favilla, T Castelli, M Chisari, A Caramma, F Patti, S Cimino, G Morgia
BACKGROUND AND PURPOSE: Sexual dysfunction (SD) is prevalent in multiple sclerosis (MS) patients and affects quality of life. Furthermore, lower urinary tract dysfunction (LUTD) is common in MS patients. Our aim was to determine the relationship between urodynamic findings and SD in a cohort of MS patients with LUTD. METHODS: From January 2011 to September 2013, 135 consecutive patients with MS in remission phase and LUTD underwent a first urodynamic examination, according to the International Continence Society criteria...
March 2015: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
Aaron Saguil, Shawn Kane, Edwin Farnell
Multiple sclerosis (MS) is the most common permanently disabling disorder of the central nervous system in young adults. Relapsing remitting MS is the most common type, and typical symptoms include sensory disturbances, Lhermitte sign, motor weakness, optic neuritis, impaired coordination, and fatigue. The course of disease is highly variable. The diagnosis is clinical and involves two neurologic deficits or objective attacks separated in time and space. Magnetic resonance imaging is helpful in confirming the diagnosis and excluding mimics...
November 1, 2014: American Family Physician
Rosalie M Grivell, Chad Andersen, Jodie M Dodd
BACKGROUND: Spina bifida is a fetal neural tube defect (NTD), which may be diagnosed in utero and is compatible with life postnatally, albeit often with significant disability and morbidity. Although postnatal repair is possible, with increasing in utero diagnosis with ultrasound, the condition has been treated during pregnancy (prenatal repair) with the aim of decreased morbidity for the child. The procedure that is performed during pregnancy does have potential morbidities for the mother, as it involves maternal surgery to access the fetus...
2014: Cochrane Database of Systematic Reviews
Nobuhiko Okamoto, Fuyuki Miya, Tatsuhiko Tsunoda, Keiko Yanagihara, Mitsuhiro Kato, Shinji Saitoh, Mami Yamasaki, Yonehiro Kanemura, Kenjiro Kosaki
Kinesins are a large superfamily of molecular motors. They move along microtubule filaments and are powered by the hydrolysis of ATP. This transport system is essential for neuronal function and survival. KIF1A belongs to the kinesin 3 family and involves in the anterograde transport of synaptic vesicle precursors along axons. Several studies confirmed that KIF1A mutations cause spastic paraplegia and sensory neuropathy in an autosomal-recessive fashion. A missense mutation in the KIF1A gene (p.Thr99Met) has been reported in a patient with intellectual disability (ID), axial hypotonia and peripheral spasticity...
November 2014: Journal of Human Genetics
L Gaspard, B Tombal, R-J Opsomer, Y Castille, V Van Pesch, C Detrembleur
AIM: This randomized controlled trial compare the efficacy of pelvic floor muscle training vs. transcutaneous posterior tibial nerve stimulation. PATIENTS AND METHODS: Inclusion criteria were EDSS score<7 and presence of lower urinary tract symptoms. Exclusion criteria were multiple sclerosis relapse during the study, active urinary tract infection and pregnancy. The primary outcome was quality of life (SF-Qualiveen questionnaire). Secondary outcomes included overactive bladder (USP questionnaire) score and frequency of urgency episodes (3-day bladder diary)...
September 2014: Progrès en Urologie
M de Sèze, X Gamé
GOAL: The aim was to review the literature on genito-urinary dysfunction in multiple sclerosis (MS). MATERIAL: A literature review through the PubMed library until August, 31 2013 was carried out using the following keywords: multiple sclerosis and neurogenic bladder, neuropathic bladder, bladder, management, follow-up, urological complications, urological treatment, sexual dysfunction, female sexual function, male sexual function, erectile dysfunction, anorectal, faecal, constipation, bowel, pregnancy, parturition, delivery, breast-feeding...
June 2014: Progrès en Urologie
Marc Possover
STUDY OBJECTIVE: To show a new technique of laparoscopic implantation of electrodes for stimulation of the pudendal nerve for treatment of fecal incontinence and/or overactive bladder with urinary incontinence. DESIGN: Step-by-step explanation of the technique using videos and pictures (educative video). SETTING: Hyperactivity of the bladder with urinary incontinence, in particular the non-neurogenic form of the condition, but also fecal incontinence may affect millions of women worldwide without any comorbidities and in particular without any neurologic disorders or prolapsed organs...
September 2014: Journal of Minimally Invasive Gynecology
Gael J Yonnet, Anette S Fjeldstad, Noel G Carlson, John W Rose
Bladder dysfunction in multiple sclerosis (MS) can be socially disabling, have negative psychological and economic consequences, and impair patients' quality of life. Knowledge of the functional anatomy and physiology of the urinary tract is essential to understand the symptoms associated with central nervous system lesions and the pharmacotherapies used to treat them. Treatments for neurogenic detrusor overactivity (NDO) have consisted mainly of administration of anticholinergic drugs, which have been shown to provide suboptimal clinical benefits and be poorly tolerated...
2013: International Journal of MS Care
Nicolas Mingat, Emmanuel Villar, Julien Allard, Evelyne Castel-Lacanal, Julien Guillotreau, Bernard Malavaud, Pascal Rischmann, Ivan Tack, Alain Ruffion, Xavier Gamé
OBJECTIVE: To evaluate the precision of methods used to assess renal function in patients with neurogenic voiding dysfunction. MATERIALS AND METHODS: This multicenter prospective study, which was set in Toulouse and Lyon, France, included 60 patients (mean age, 48.9 ± 15.2 years) with neurogenic bladder and sphincter dysfunction. The correlation and the concordance with the inulin clearance of each method of renal function evaluation were assessed. RESULTS: The correlation of serum creatinine with inulin clearance was low when using serum creatinine-based equations such as the Modification of Diet in Renal Disease (simplified and complete) and Cockcroft-Gault equations...
November 2013: Urology
P G Shvarts, V V Dutov, A S Kadykov, V V Shvedkov, S V Popov, A N Plotnikov
Disorders of urination, along with motor and cognitive disorders, are characteristic of different forms of chronic cerebral vascular diseases (CCVD). Irritation symptoms are more frequent in subcortical arteriosclerotic encephalopathy (SAE) and multi infarct hypertonic encephalopathy (MIHE). Overactive urine bladder syndrome (OUBS) caused by neurogenic detrusive hyperactivity manifests itself in frequent urination, nocturia and imperative enuresis and thus decreases quality of life and results in disability of patents with CCVD...
2013: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
Dogan Kose, Yahya Paksoy, Yavuz Koksal, Ekrem Unal
PURPOSE: Lymphomas are the third most common childhood malignant disease after leukemia and central nervous system (CNS) tumors. Early diagnosis of these complications will reduce mortality and morbidity. In this study we aimed to review the neurological complications of childhood non Hodgkin Lymphoma (NHL). PATIENTS AND METHODS: Forty four children with NHL between 2006 and 2012 were investigated retrospectively and 14 cases with neurological complications were identified...
April 2014: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
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