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https://www.readbyqxmd.com/read/29331224/centrifugal-partition-chromatography-enables-selective-enrichment-of-trimeric-and-tetrameric-proanthocyanidins-for-biomaterial-development
#1
Rasika S Phansalkar, Joo-Won Nam, Shao-Nong Chen, James B McAlpine, Ariene A Leme, Berdan Aydin, Ana-Karina Bedran-Russo, Guido F Pauli
Proanthocyanidins (PACs) find wide applications for human use including food, cosmetics, dietary supplements, and pharmaceuticals. The chemical complexity associated with PACs has triggered the development of various chromatographic techniques, with countercurrent separation (CCS) gaining in popularity. This study applied the recently developed DESIGNER (Depletion and Enrichment of Select Ingredients Generating Normalized Extract Resources) approach for the selective enrichment of trimeric and tetrameric PACs using centrifugal partition chromatography (CPC)...
December 21, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29325862/antibacterial-effects-of-cinnamon-cinnamomum-zeylanicum-bark-essential-oil-on-porphyromonas-gingivalis
#2
Yue Wang, Yi Zhang, Yan-Qin Shi, Xian-Hua Pan, Yan-Hua Lu, Ping Cao
The objective of this study was to investigate the antibacterial effects of cinnamon (Cinnamomum zeylanicum) bark essential oil (CBEO) and its principal constituent cinnamaldehyde against Porphyromonas gingivalis and to elucidate the antibacterial mechanism. GC-MS analysis showed that cinnamaldehyde was the major constituent in CBEO (57.97%). The minimum inhibition concentrations (MICs) of CBEO and cinnamaldehyde were 6.25 μg/mL and 2.5 μM for P. gingivalis, respectively. Nucleic acid and protein leakage was observed with increasing concentrations of CBEO and cinnamaldehyde...
January 8, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29322000/effects-of-cinnamon-supplementation-on-antioxidant-status-and-serum-lipids-in-women-with-polycystic-ovary-syndrome
#3
Azam Borzoei, Maryam Rafraf, Shirin Niromanesh, Laya Farzadi, Fateme Narimani, Farideh Doostan
Background: The objectives of study were to investigate the effects of cinnamon supplementation on antioxidant status and serum lipids in women with polycystic ovary syndrome (PCOS). Methods: This double-blind randomized controlled clinical trial was conducted on 84 overweight or obese PCOS patients; aged 20-38 years. Subjects in cinnamon (n = 42) and placebo (n = 42) groups were given 3 cinnamon capsules (each one contained 500 mg cinnamon) or placebo daily for 8 weeks...
January 2018: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29321988/hypolipidemic-effects-of-s-linalool-and-essential-oil-from-cinnamomum-osmophloeum-ct-linalool-leaves-in-mice
#4
Bing-Ho Cheng, Lee-Yan Sheen, Shang-Tzen Chang
Cinnamomum osmophloeum ( tǔ ròu guì) ct. linalool is one of the chemotypes of the indigenous cinnamon in Taiwan. S-(+)-linalool is the major constituent of leaf essential oil (LEO) of C. osmophloeum ct. linalool. This study aimed to investigate its physiological effects including body weight changes, blood biochemical values, and histopathological changes in mice. The mice were treated with LEO, S-(+)-linalool, and R-(-)-linalool. Results demonstrated similar physiological changes in mice treated with LEO and S-(+)-linalool, but significantly different effects in the body weight, TG, TC and blood glucose of R-(-)-linalool group...
January 2018: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29319361/cinnamon-cinnamomum-zeylanicum-as-an-antidote-or-a-protective-agent-against-natural-or-chemical-toxicities-a-review
#5
Mahyar Dorri, Shirin Hashemitabar, Hossein Hosseinzadeh
Cinnamon (Cinnamomum zeylanicum, Lauraceae) is a food additive greatly used for its taste. However, recently this medicinal plant has been brought to attention due to its medical effects. Cinnamon has constituents such as cinnamaldehyde and cinnamic acid that offers some health benefits including antioxidant and free-radical scavenging properties, lowering of blood glucose, anti-cholesterolemic, analgesic, antimicrobial, anti-inflammatory, anti-yeast, anti-secretagogue, and anti-gastric ulcer effects. This review summarizes various in vitro and animal studies on the protective effects of cinnamon against natural and chemical toxins...
January 10, 2018: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/29301737/privacy-policies-for-apps-targeted-toward-youth-descriptive-analysis-of-readability
#6
Gitanjali Das, Cynthia Cheung, Camille Nebeker, Matthew Bietz, Cinnamon Bloss
BACKGROUND: Due to the growing availability of consumer information, the protection of personal data is of increasing concern. OBJECTIVE: We assessed readability metrics of privacy policies for apps that are either available to or targeted toward youth to inform strategies to educate and protect youth from unintentional sharing of personal data. METHODS: We reviewed the 1200 highest ranked apps from the Apple and Google Play Stores and systematically selected apps geared toward youth...
January 4, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29298969/-dietetary-recommendation-for-non-alcoholic-fatty-liver-disease
#7
REVIEW
Anna Jeznach-Steinhagen, Joanna Ostrowska, Aneta Czerwonogrodzka-Senczyna, Iwona Boniecka, Wioletta Gronostajska
Non-alcoholic Fatty Liver Disease (NAFLD) is currently the most common chronic liver disease in the developed world. Nowadays, in the adult population of Europe it is estimated at 14% to 21%. Its most important risk factors are obesity and metabolic syndrome. Introducing lifestyle changes such as: dietary intervention and increased physical activity are the first-line treatment and are intended to support not only NAFLD but also associated diseases such as obesity, insulin resistance, diabetes and dyslipidemia...
December 22, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29287447/the-effect-of-edible-coating-based-on-arabic-gum-sodium-caseinate-and-essential-oil-of-cinnamon-and-lemon-grass-on-guava
#8
Sanchita Biswas Murmu, Hari Niwas Mishra
The effect of five coating formulations viz.: (A) 5% Arabic gum (AG)+1% sodium caseinate (SC)+1% cinnamon oil (CE); (B) 5% AG + 1% SC + 2% CE; (C) 5% AG + 1% SC + 1% lemongrass oil (LG); (D) 5% AG + 1% SC + 2% LG; and (E) 5% AG + 1% SC + 2% CE + 2% LG on guava during 35 days storage at 4-7 °C was investigated. Thereafter samples were allowed to ripen for five days at 25 ± 2 °C. The quality of guava was analyzed at an interval of 7, 21, 35 and 40 days. The coating applications resulted in lower activity of PPO & POD, higher DPPH radical scavenging activity, higher retention of ascorbic acid, phenol & flavonoid content, exhibited slower rise of reducing and total sugar in guava pulp...
April 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29286537/investigating-the-relationships-between-alcohol-consumption-cannabis-use-and-circulating-cytokines-a-preliminary-analysis
#9
Hollis C Karoly, L Cinnamon Bidwell, Raeghan Mueller, Kent Hutchison
BACKGROUND: In recent years, human and animal studies have converged to support altered inflammatory signaling as one molecular mechanism underlying the pathophysiology of alcohol use disorders (AUDs). Alcohol binds to receptors on immune cells, triggering signaling pathways that produce pro-inflammatory cytokines. Chronic inflammation is associated with tissue damage, which may contribute to negative effects of AUD. Conversely, cannabis is associated with decreased inflammatory signaling, and animal studies suggest that cannabinoids may impact alcohol-induced inflammation...
December 29, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29284146/antioxidative-and-immunostimulatory-effect-of-dietary-cinnamon-nanoparticles-on-the-performance-of-nile-tilapia-oreochromis-niloticus-l-and-its-susceptibility-to-hypoxia-stress-and-aeromonas-hydrophila-infection
#10
Mohsen Abdel-Tawwab, Fatma Samir, Asmaa S Abd El-Naby, Mohamed N Monier
An experiment was conducted to evaluate the effect of dietary cinnamon nanoparticles (CNP) on growth performance, antioxidant and digestive enzymes activities, and innate immunity of Nile tilapia, Oreochromis niloticus (L.). Fish (9.7 ± 0.3 g) were fed on diets enriched with 0.0, 0.25, 0.5, 1.0, 3.0, 5.0, and 10.0 g CNP/kg diet for 8 weeks. After the feeding trial, fish were challenged against hypoxia stress or pathogenic bacteria (Aeromonas hydrophila) infection. Fish performance was significantly improved with increasing CNP levels over the control diet...
December 25, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29282046/evaluation-of-pharmacodynamic-properties-and-safety-of-cinnamomum-zeylanicum-ceylon-cinnamon-in-healthy-adults-a-phase-i-clinical-trial
#11
Priyanga Ranasinghe, Ranil Jayawardena, Shehani Pigera, Wasundara Sevwandi Wathurapatha, Hasitha Dhananjaya Weeratunga, G A Sirimal Premakumara, Prasad Katulanda, Godwin Roger Constantine, Priyadarshani Galappaththy
BACKGROUND: Cinnamon is considered as a treatment for many ailments in native medicine. Evidence suggests that Cinnamomum zeylanicum (CZ) has anti-microbial, anti-parasitic, anti-oxidant, blood glucose lowering properties and beneficial cardiovascular effects. The present study aims to evaluate Pharmacodynamic properties and safety of CZ in healthy adults using a Phase I Clinical Trial. METHODS: This phase I clinical trial was conducted at the Department of Pharmacology, Faculty of Medicine, University of Colombo, Sri Lanka...
December 28, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29258915/cinnamon-a-promising-prospect-towards-alzheimer-s-disease
#12
REVIEW
Saeideh Momtaz, Shokoufeh Hassani, Fazlullah Khan, Mojtaba Ziaee, Mohammad Abdollahi
Over the last decades, an exponential increase of efforts concerning the treatment of Alzheimer's disease (AD) has been practiced. Phytochemicals preparations have a millenary background to combat various pathological conditions. Various cinnamon species and their biologically active ingredients have renewed the interest towards the treatment of patients with mild-to-moderate AD through the inhibition of tau protein aggregation and prevention of the formation and accumulation of amyloid-β peptides into the neurotoxic oligomeric inclusions, both of which are considered to be the AD trademarks...
December 16, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29250843/insulin-resistance-improvement-by-cinnamon-powder-in-polycystic-ovary-syndrome-a-randomized-double-blind-placebo-controlled-clinical-trial
#13
Mahdie Hajimonfarednejad, Majid Nimrouzi, Mojtaba Heydari, Mohammad Mehdi Zarshenas, Mohammad Javad Raee, Bahia Namavar Jahromi
Our aim is to assess the effect of cinnamon powder capsules on insulin resistance, anthropometric measurements, glucose and lipid profiles, and androgens of women with polycystic ovarian syndrome (PCOS). Out of 80 women that were diagnosed as PCOS by Rotterdam Criteria, 66 were enrolled in this randomized double-blind placebo-controlled clinical trial. All of the PCOS women were taking medroxy progesterone acetate 10 mg/day for the last 10 days of their menstrual cycles. The cases were randomly allocated to 2 groups...
December 18, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29246829/hyperspectral-imaging-for-label-free-in-vivo-identification-of-myocardial-scars-and-sites-of-radiofrequency-ablation-lesions
#14
Luther M Swift, Huda Asfour, Narine Muselimyan, Cinnamon Larson, Kenneth Armstrong, Narine A Sarvazyan
BACKGROUND: Treatment of cardiac arrhythmias often involves ablating viable muscle tissue within or near islands of scarred myocardium. Yet, today there are limited means by which the boundaries of such scars can be visualized during surgery and distinguished from the sites of acute injury caused by radiofrequency (RF) ablation. OBJECTIVE: We sought to explore a hyperspectral imaging (HSI) methodology to delineate and distinguish scar tissue from tissue injury caused by RF ablation...
December 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29238281/differential-inhibitory-activities-of-four-plant-essential-oils-on-in-vitro-growth-of-fusarium-oxysporum-f-sp-fragariae-causing-fusarium-wilt-in-strawberry-plants
#15
Jin Young Park, Su Hyeon Kim, Na Hee Kim, Sang Woo Lee, Yong-Chull Jeun, Jeum Kyu Hong
The objective of this study was to determine inhibitory activities of four volatile plant essential oils (cinnamon oil, fennel oil, origanum oil and thyme oil) on in vitro growth of Fusarium oxysporum f. sp. fragariae causing Fusarium wilt of strawberry plants. Results showed that these essential oils inhibited in vitro conidial germination and mycelial growth of F. oxysporum f. sp. fragariae in a dose-dependent manner. Cinnamon oil was found to be most effective one in suppressing conidial germination while fennel oil, origanum oil and thyme oil showed moderate inhibition of conidial germination at similar levels...
December 2017: Plant Pathology Journal
https://www.readbyqxmd.com/read/29237511/toxic-effects-of-two-essential-oils-and-their-constituents-on-the-mealworm-beetle-tenebrio-molitor
#16
L C Martínez, A Plata-Rueda, H C Colares, J M Campos, M H Dos Santos, F L Fernandes, J E Serrão, J C Zanuncio
The study identified insecticidal effects from the cinnamon and clove essential oils in Tenebrio molitor L. (Coleoptera: Tenebrionidae). The lethal concentrations (LC50 and LC90), lethal time, and repellent effect on larvae, pupae, and adults of T. molitor after exposure to six concentrations of each essential oil and toxic compounds were evaluated. The chemical composition of the cinnamon oil was also determined and primary compounds were eugenol (10.19%), trans-3-caren-2-ol (9.92%), benzyl benzoate (9.68%), caryophyllene (9...
December 14, 2017: Bulletin of Entomological Research
https://www.readbyqxmd.com/read/29231606/-clinical-study-of-medicinal-cake-separated-moxibustion-for-senile-osteoporosis
#17
Yuqing Zeng, Dingyan Bi, Zhan Yi, Jianwei Lu, Fuhua Zhong, Binfeng Jiang
OBJECTIVE: To explore the clinical efficacy and partial mechanism of medicinal-cake-separated moxibustion for senile osteoporosis. METHODS: Sixty cases of senile osteoporosis were randomly divided into an observation group and a control group according to the random digits table, 30 cases in each one. The two groups were both treated with basic treatment of western medicine. The acupoints included four groups:① Dazhui (GV 14), Dazhu (BL 11) and Ganshu (BL 18); ② Zhongwan (CV 12), Danzhong (CV 17) and Zusanli (ST 36); ③ Pishu (BL 20), Shenshu (BL 23) and Mingmen (GV 4); ④ Shenque (CV 8) and Guanyuan (CV 4)...
May 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29224633/over-the-counter-medicines-and-diabetes-care
#18
Jeff Taylor
OBJECTIVES: People with diabetes turn to over-the-counter (OTC) medicines for many ailments. The focus of this brief review is the impact common OTC medicines might have on this group of patients. METHODS: Three types of OTC medicines were selected as most deserving of attention: 3 herbal agents, nonsteroidal anti-inflammatory drugs (NSAIDs) and cough/cold products. Existing literature was used to determine precautions that might be in order. RESULTS: Herbal/natural agents with the potential to impact blood sugar have been identified in various reports...
December 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29221803/optimizing-non-pharmacologic-management-of-hypertriglyceridemia
#19
REVIEW
Alexandra Byrne, Sunal Makadia, Aimee Sutherland, Michael Miller
The cornerstone of initial management for hypertriglyceridemia (HTG) is lifestyle modification. The combination of weight loss through caloric restriction, alteration in macronutrient composition and increased energy expenditure reduces TG levels by approximately 50%. The addition of cinnamon, cacao products and isocaloric substitution of 1 serving of nuts may contribute another 5-15% lowering of TG. This can be particularly beneficial in patients with HTG who are at increased risk of cardiovascular disease...
December 5, 2017: Archives of Medical Research
https://www.readbyqxmd.com/read/29209220/the-traditional-japanese-herbal-medicine-hachimijiogan-elicits-neurite-outgrowth-effects-in-pc12-cells-and-improves-cognitive-in-ad-model-rats-via-phosphorylation-of-creb
#20
Kaori Kubota, Haruka Fukue, Hitomi Sato, Kana Hashimoto, Aya Fujikane, Hiroshi Moriyama, Takuya Watanabe, Shutaro Katsurabayashi, Mosaburo Kainuma, Katsunori Iwasaki
Hachimijiogan (HJG) is a traditional herbal medicine that improves anxiety disorders in patients with dementia. In this study, we tested the hypothesis that HJG exerts neurotrophic factor-like effects to ameliorate memory impairment in Alzheimer disease (AD) model rats. First, we describe that HJG acts to induce neurite outgrowth in PC12 cells (a rat pheochromocytoma cell line) like nerve growth factor (NGF) in a concentration-dependent manner (3 μg/ml HJG, p < 0.05; 10-500 μg/ml HJG, p < 0.001). While six herbal constituents of HJG, Rehmannia root, Dioscorea rhizome, Rhizoma Alismatis, Poria sclerotium, Moutan bark, and Cinnamon bark, could induce neurite outgrowth effects, the effect was strongest with HJG (500 μg/ml)...
2017: Frontiers in Pharmacology
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