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https://www.readbyqxmd.com/read/29776697/cinnamtannin-b-1-a-novel-antioxidant-for-sperm-in-red-deer
#1
F Sánchez-Rubio, M R Fernández-Santos, L Castro-Vázquez, O García-Álvarez, A Maroto-Morales, A J Soler, F Martínez-Pastor, J J Garde
Cinnamtannin B-1 (CNB-1) is a naturally occurring trimeric A-type proanthocyanidin contained in several plants such as cinnamon (Cinnamomum zeylanicum). It is considered to be a potent antioxidant. The protective effect of CNB-1 against oxidative stress was assessed in red deer epididymal sperm incubated at 37 °C. Cryopreserved sperm from six stags were thawed, pooled and extended to 400 × 106 sperm/ml in BGM (bovine gamete medium). After being aliquoted, the samples were supplemented with different concentrations of CNB-1 (0, 0...
May 15, 2018: Animal Reproduction Science
https://www.readbyqxmd.com/read/29769067/antioxidant-capacity-of-cinnamon-extract-for-palm-oil-stability
#2
Muhammad Zia Shahid, Hafiza Saima, Adeela Yasmin, Muhammad Tahir Nadeem, Muhammad Imran, Muhammad Afzaal
BACKGROUND: Spices and their bioactive components are more promising attractions for their inclusion in diet-based regimes to improve human health. These are sources of natural antioxidants and play an important role in the chemoprevention of diseases and aging. The aim of the current study was to explore the antioxidant potential of cinnamon; a widely used spice throughout the world. METHODS: The current research was aimed to investigate the antioxidant potential of cinnamon extract...
May 16, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29761921/trans-cinnamic-aldehyde-inhibit-aggregatibacter-actinomycetemcomitans-induced-inflammation-thp-1-derived-macrophages-via-autophagy-activation
#3
Jin Chung, Sumi Kim, Hyun Ah Lee, Mi Hee Park, Seyeon Kim, Yu Ri Song, HeeSam Na
OBJECTIVES: Inflammation is an essential response against bacterial infection as a host defense mechanism, which can lead to tissue damage. Aggregatibacter actinomycetemcomitans (Aa) is major pathogen for aggressive periodontitis characterized by rapid destruction of periodontal tissue surrounding teeth. Trans-cinnamic aldehyde is a key bioactive compound of the cinnamon extracts, which has anti-inflammatory, antioxidant, antipyretic, antimicrobial, and anti-cancer properties. The objective of the present study was to investigate the anti-inflammatory effect of trans-cinnamic aldehyde against Aa infection in human THP-1 derived macrophages and on Aa-induced periodontitis in mice...
May 15, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/29751902/impact-of-chitosan-based-edible-coatings-functionalized-with-natural-compounds-on-colletotrichum-fragariae-development-and-the-quality-of-strawberries
#4
R I Ventura-Aguilar, S Bautista-Baños, G Flores-García, L Zavaleta-Avejar
The antifungal effect of chitosan edible coatings (ChEC) functionalized with cinnamon essential oil and aqueous extract of Roselle calyces on Colletotrichum fragariae growth and physical-chemical, physiological and nutraceutical features of strawberries at 5 and 20 °C were evaluated. ChEC was characterized with respect to its water vapor permeability (WVP) and mechanical properties. Results indicated that C. fragariae grew from the third day in strawberries stored at 20 °C, whilst at 5 °C disease symptoms were observed after 10 days in fruit inoculated and treated with ChEC after 24 h...
October 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29750248/physician-preparedness-for-big-genomic-data-a-review-of-genomic-medicine-education-initiatives-in-the-united-states
#5
Caryn Kseniya Rubanovich, Cynthia Cheung, Jess Mandel, Cinnamon S Bloss
In the last decade, genomic medicine education initiatives have surfaced across the spectrum of physician training in order to help address a gap in genomic medicine preparedness among physicians. The approaches are diverse and stem from the belief that 21st century physicians must be proficient in genomic medicine applications as they will be leaders in the precision medicine movement. We conducted a review of literature in genomic medicine education and training for medical students, graduate medical education, and practicing physicians with articles published between June 2015 and January 2018 to gain a picture of the current state of genomic medicine education with a focus on the United States...
May 10, 2018: Human Molecular Genetics
https://www.readbyqxmd.com/read/29738503/investigation-of-the-antifungal-activity-and-mode-of-action-of-thymus-vulgaris-citrus-limonum-pelargonium-graveolens-cinnamomum-cassia-ocimum-basilicum-and-eugenia-caryophyllus-essential-oils
#6
Katarzyna Gucwa, Sławomir Milewski, Tomasz Dymerski, Piotr Szweda
The antimicrobial activity of plant oils and extracts has been recognized for many years. In this study the activity of Thymus vulgaris , Citrus limonum , Pelargonium graveolens , Cinnamomum cassia , Ocimum basilicum , and Eugenia caryophyllus essential oils (EOs) distributed by Pollena Aroma (Nowy Dwór Mazowiecki, Poland) was investigated against a group of 183 clinical isolates of C. albicans and 76 isolates of C. glabrata . All of the oils exhibited both fungistatic and fungicidal activity toward C. albicans and C...
May 8, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29737802/cinnamon-improves-metabolic-factors-without-detectable-effects-on-adiponectin-in-women-with-polycystic-ovary-syndrome
#7
Azam Borzoei, Maryam Rafraf, Mohammad Asghari-Jafarabadi
BACKGROUND AND OBJECTIVES: The objectives of this study were to investigate the effects of cinnamon supplementation on glycemic indices, serum lipids and adiponectin in patients with polycystic ovary syndrome (PCOS). METHODS AND STUDY DESIGN: This double-blind randomized controlled clinical trial was conducted on 84 overweight or obese PCOS patients. Subjects in cinnamon (n=42) and placebo (n=42) groups were given 3 cinnamon capsules (each one contained 500 mg cinnamon) or placebo daily for 8 weeks...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29733733/characteristics-of-likely-precision-medicine-initiative-participants-drawn-from-a-large-blood-donor-population
#8
Cinnamon S Bloss, Justin Stoler, Cynthia E Schairer, Sara B Rosenthal, Cynthia Cheung, Holly M Rus, Jessica L Block, Jiue-An Jay Yang, Doug Morton, Helen Bixenman, David Wellis
A goal of the Precision Medicine Initiative All of Us Research Program (AoURP) is recruitment of participants who reflect the diversity of the US. Recruitment from among blood bank donors, which may better reflect the demographic makeup of local communities, is one proposed strategy. We evaluated this strategy by analyzing the results of a survey of San Diego Blood Bank donors conducted in November 2015. Whites were more likely than nonwhites to respond to the survey (7.1 percent versus 3.9 percent). However, race was not a significant predictor of interest in participating in precision medicine research...
May 2018: Health Affairs
https://www.readbyqxmd.com/read/29732971/upregulation-of-suppressor-of-cytokine-signaling-3-in-microglia-by-cinnamic-acid
#9
Sudipta Chakrabarti, Malabendu Jana, Avik Roy, Kalipada Pahan
Neuroinflammation plays an important role in the pathogenesis of various neurodegenerative diseases including Alzheimer's disease (AD). Suppressor of cytokine signaling 3 (SOCS3) is an anti-inflammatory molecule that suppresses cytokine signaling and inflammatory gene expression in different cells including microglia. However, pathways through which SOCS3 could be upregulated are poorly described. Cinnamic acid is a metabolite of cinnamon, a natural compound that is being widely used all over the world as a spice or flavoring agent...
May 6, 2018: Current Alzheimer Research
https://www.readbyqxmd.com/read/29722610/cinnamon-consumption-improves-clinical-symptoms-and-inflammatory-markers-in-women-with-rheumatoid-arthritis
#10
Farideh Shishehbor, Mahnaz Rezaeyan Safar, Elham Rajaei, Mohammad Hosein Haghighizadeh
OBJECTIVE: This study evaluated the effect of cinnamon on disease activity, serum levels of some inflammatory markers, and cardiovascular risk factors in women with rheumatoid arthritis (RA). METHODS: In this randomized double-blind clinical trial, 36 women with RA were randomly divided to 2 groups, receiving 4 capsules of either 500 mg cinnamon powder or placebo daily for 8 weeks. Fasting blood sugar (FBS), lipid profile, liver enzymes, serum levels of C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), erythrocyte sedimentation rate (ESR), blood pressure, and clinical symptoms were determined at baseline and end of the week 8...
May 3, 2018: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29714150/cinnamon-polyphenol-extract-exerts-neuroprotective-activity-in-traumatic-brain-injury-through-modulation-of-nfr2-and-cytokine-expression
#11
Burak Yulug, Ertugrul Kilic, Serdar Altunay, Cenk Ersavas, Cemal Orhan, Arman Dalay, Nurhan Sahin, Mehmet Tuzcu, Vijaya Juturu, Kazim Sahin
INTRODUCTION: Cinnamon cinnamon polyphenol extract is a traditional spice commonly used in different areas of the world for treatment of different disease conditions which are associated with inflammation and oxidative stress. Despite many preclinical studies showing the anti-oxidative, anti-inflammatory effects of CN, the underlying mechanisms in signaling pathways via which cinnamon protects the brain after brain trauma remained largely unknown. However, there is still no preclinical study delineating the possible molecular mechanism of neuroprotective effects cinnamon polyphenol extractin TBI...
April 30, 2018: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/29705440/the-association-between-quality-of-life-and-complementary-and-alternative-medicine-use-in-patients-with-diabetes-mellitus
#12
Ali Candar, Hakan Demirci, Ayse Karalar Baran, Yakup Akpınar
AIM: In the current study, we aimed to evaluate the relationship between life quality and use of complementary and alternative medicine (CAM) in patients with diabetes mellitus. METHODS: The Audit of Diabetes-Dependent Quality of Life (ADDQOL-19) scale was applied to 453 diabetic patients. Socio-demographic characteristics of the patients and their CAM usage were recorded. RESULTS: The rate of CAM use among diabetic patients was 46.1%. The most preferred practices were herbal medicine, including black cumin (26...
May 2018: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29702210/antibacterial-mechanisms-of-cinnamon-and-its-constituents-a-review
#13
REVIEW
N G Vasconcelos, J Croda, S Simionatto
BACKGROUND: In the current healthcare environment, an alarming rise in multi-drug resistant bacterial infections has led to a global health threat. The lack of new antibiotics has created a need for developing alternative strategies. OBJECTIVE: Understanding the antibacterial mechanisms of Cinnamon and its constituents is crucial to enhance it as a potential new source of antibiotic. The objective of this review is to provide a compilation of all described mechanisms of antibacterial action of Cinnamon and its constituents and synergism with commercial antibiotics in order to better understand how Cinnamon and its constituents can collaborate as alternative treatment to multi-drug resistant bacterial infections...
April 24, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29688798/susceptibility-distribution-to-essential-oils-of-salmonella-enterica-strains-involved-in-animal-and-public-health-and-comparison-of-the-typhimurium-and-enteritidis-serotypes
#14
Ana Lucía Solarte, Rafael Jesús Astorga, Fabiana Carolina de Aguiar, Cristina De Frutos, Belén Barrero-Domínguez, Belén Huerta
To determine the distribution of the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of essential oils (EOs) of cinnamon (Cinnamomum zeylanicum), clove (Eugenia caryophyllata), oregano (Origanum vulgare), common thyme (Thymus vulgaris), and red thyme (Thymus zygis) against Salmonella enterica, double serial dilutions of each EO were challenged with 85 Salmonella strains belonging to 23 serotypes of animal origin. The results showed the bactericidal character of the EOs tested against S...
April 24, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29687910/failure-to-find-ethanol-induced-conditioned-taste-aversion-in-honey-bees-apis-mellifera-l
#15
Christopher A Varnon, Christopher W Dinges, Tim E Black, Harrington Wells, Charles I Abramson
BACKGROUND: Conditioned taste aversion (CTA) learning is a highly specialized form of conditioning found across taxa that leads to avoidance of an initially neutral stimulus, such as taste or odor, that is associated with, but is not the cause of, a detrimental health condition. The present study examines if honey bees (Apis mellifera L.) develop ethanol-induced CTA. METHODS: Restrained bees were first administered a sucrose solution that was cinnamon scented, lavender scented, or unscented, and contained either 0%, 2...
April 24, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29681979/kainari-a-unique-greek-traditional-herbal-tea-from-the-island-of-lesvos-chemical-analysis-and-antioxidant-and-antimicrobial-properties
#16
Evangelia Bampali, Konstantia Graikou, Nektarios Aligiannis, Ioanna Chinou
The chemical composition, as well as the total phenolic content (TPC) and the potential antioxidant and antimicrobial activity, of three Kainari-herbal tea samples from different areas of Lesvos Island (Greece) was evaluated. The rich aroma of the mixtures was studied through GC-MS, as well as through Headspace Solid-Phase Microextraction (HS-SPME)/GC-MS analyses. Cinnamon, clove, nutmeg, pepper, and ginger were identified as main ingredients, while, throughout the chemical analysis of the volatiles of one selected sample, several secondary metabolites have been isolated and identified on the basis of GC-MS as well as spectral evidence as eugenol, cinnamic aldehyde and myristicin, cinnamyl alcohol, alpha-terpinyl acetate, and β -caryophyllene...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29674380/odor-discrimination-learning-in-the-indian-greater-short-nosed-fruit-bat-cynopterus-sphinx-differential-expression-of-egr-1-c-fos-and-pp-1-in-the-olfactory-bulb-amygdala-and-hippocampus
#17
Murugan Mukilan, Wieslaw Bogdanowicz, Ganapathy Marimuthu, Koilmani Emmanuvel Rajan
Activity-dependent expression of immediate-early genes (IEGs) is induced by exposure to odor. The present study was designed to investigate whether there is differential expression of IEGs ( Egr-1 , C-fos ) in the brain region mediating olfactory memory in the Indian greater short-nosed fruit bat Cynopterus sphinx We assumed that differential expression of IEGs in different brain regions may orchestrate a preference odor (PO) and aversive odor (AO) memory in C. sphinx We used preferred (0.8% wt/wt of cinnamon powder) and aversive (0...
April 19, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29666549/reinforced-cassava-starch-based-edible-film-incorporated-with-essential-oil-and-sodium-bentonite-nanoclay-as-food-packaging-material
#18
Butsadee Iamareerat, Manisha Singh, Muhammad Bilal Sadiq, Anil Kumar Anal
Biodegradable packaging in food materials is a green technology based novel approach to replace the synthetic and conventional packaging systems. This study is aimed to formulate the biodegradable cassava starch based films incorporated with cinnamon essential oil and sodium bentonite clay nanoparticles. The films were characterized for their application as a packaging material for meatballs. The cassava starch films incorporated with sodium bentonite and cinnamon oil showed significant antibacterial potential against all test bacteria; Escherichia coli , Salmonella typhimurium and Staphylococcus aureus...
May 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29661513/cinnamon-a-systematic-review-of-adverse-events
#19
REVIEW
Mahdie Hajimonfarednejad, Mohadeseh Ostovar, Mohammad Javad Raee, Mohammad Hashem Hashempur, Johannes Gottfried Mayer, Mojtaba Heydari
Cinnamon, from the genus Cinnamomum and Lauraceae family, has been used as a popular spice for thousands of years around the world. Many studies have shown therapeutic effects of cinnamon including its antimicrobial, antiviral, antifungal, antioxidant, antitumor, antihypertensive, antilipemic, antidiabetic, gastroprotective, and immunomodulatory effects. Due to popular use of cinnamon and several human reports on adverse events associated with short or long term use of cinnamon, we aimed to systematically review its human reports of adverse event...
April 5, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29660773/active-chicken-meat-packaging-based-on-polylactide-films-and-bimetallic-ag-cu-nanoparticles-and-essential-oil
#20
Jasim Ahmed, Yasir Ali Arfat, Anibal Bher, Mehrajfatema Mulla, Harsha Jacob, Rafael Auras
Plasticized polylactide (PLA) composite films with multifunctional properties were created by loading bimetallic silver-copper (Ag-Cu) nanoparticles (NPs) and cinnamon essential oil (CEO) into polymer matrix via compression molding technique. Rheological, structural, thermal, barrier, and antimicrobial properties of the produced films, and its utilization in the packaging of chicken meat were investigated. PLA/PEG/Ag-Cu/CEO composites showed a very complex rheological system where both plasticizing and antiplasticizing effects were evident...
April 16, 2018: Journal of Food Science
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