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https://www.readbyqxmd.com/read/27896585/effect-of-an-herbal-mixture-of-cinnamon-cortex-persicae-semen-and-natril-sulfas-on-collagen-induced-arthritis-and-lipopolysaccharides-induced-nuclear-factor-%C3%AE%C2%BA-b-signaling
#1
Ji-Won Lee, Jae-Hwan Lew, Tae-Woo Kim, Hee Kang
OBJECTIVE: To investigate the anti-arthritic and anti-inflammatory effects of the mixture of three herbal agents, Cinnamon Cortex, Persica Semen, and Natril Sulfas (CPN), the major ingredients of Taoren Chengqi Decoction (). METHODS: Collagen-induced arthritis (CIA) was induced by immunization with bovine type II collagen on day 1 and 21. DBA/1J mice were orally administered the water extract of CPN (100 and 500 mg/kg) and indomethacin (1 mg/kg) or vehicle (water) 3 times per week for 6 weeks...
November 17, 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27892897/the-importance-of-selected-spices-in-cardiovascular-diseases
#2
Bartosz Kulczyński, Anna Gramza-Michałowska
Cardiovascular diseases are the leading cause of death worldwide. Literature data indicate that, due to these diseases, approximately 17.5 million people died in 2012. Types of cardiovascular disease include ischemic heart disease, cerebrovascular disease, peripheral vascular disease, congenital heart disease, rheumatic heart disease, cardiomyopathy and arrhythmia. Proper nutrition is an important factor in reducing the risk of cardiovascular events. An interesting element of our diets is spices. For thousands of years, they have been used in the treatment of many diseases: bacterial infections, coughs, colds, and liver diseases...
November 14, 2016: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/27889776/cinnamic-acid-cinn-induces-apoptosis-and-proliferation-in-human-nasopharyngeal-carcinoma-cells
#3
Guangying Qi, Jian Chen, Changrong Shi, Yukun Wang, Sisi Mi, Wenhua Shao, Xiangyuan Yu, Yili Ma, Jiapu Ling, Jian Huang
BACKGROUND/AIMS: CINN is the main ingredient of the traditional Chinese medicine cinnamon. The purpose of the present study was to investigate the effects of CINN on the proliferation and apoptosis of NPC cells and to elucidate the underlying molecular mechanisms. MATERIALS AND METHODS: CNE2 human NPC cells were treated with various CINN concentrations. The effects of CINN on the proliferation and apoptosis of CNE2 NPC cells were examined using the MTT assay and flow cytometric analysis...
November 25, 2016: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/27884762/pleasantness-familiarity-and-identification-of-spice-odors-are-interrelated-and-enhanced-by-consumption-of-herbs-and-food-neophilia
#4
Antti Knaapila, Oskar Laaksonen, Markus Virtanen, Baoru Yang, Hanna Lagström, Mari Sandell
The primary dimension of odor is pleasantness, which is associated with a multitude of factors. We investigated how the pleasantness, familiarity, and identification of spice odors were associated with each other and with the use of the respective spice, overall use of herbs, and level of food neophobia. A total of 126 adults (93 women, 33 men; age 25-61 years, mean 39 years) rated the odors from 12 spices (oregano, anise, rosemary, mint, caraway, sage, thyme, cinnamon, fennel, marjoram, garlic, and clove) for pleasantness and familiarity, and completed a multiple-choice odor identification...
November 21, 2016: Appetite
https://www.readbyqxmd.com/read/27869756/a-review-of-temperature-ph-and-other-factors-that-influence-the-survival-of-salmonella-in-mayonnaise-and-other-raw-egg-products
#5
REVIEW
Thilini Piushani Keerthirathne, Kirstin Ross, Howard Fallowfield, Harriet Whiley
Salmonellosis is one of the main causes of foodborne illnesses worldwide, with outbreaks predominately linked to contamination of eggs and raw egg products, such as mayonnaise. This review explores previous studies that have investigated Salmonella control mechanisms utilized in the production of raw egg mayonnaise and other food products. Apart from the use of pasteurized eggs, the main control mechanism identified is the pH of the raw egg products, which plays an important role in the consistency and stability while affecting the survival of Salmonella spp...
November 18, 2016: Pathogens
https://www.readbyqxmd.com/read/27869684/quantitative-structure-activity-relationship-of-cinnamaldehyde-compounds-against-wood-decaying-fungi
#6
Dongmei Yang, Hui Wang, Haijian Yuan, Shujun Li
Cinnamaldehyde, of the genius Cinnamomum, is a major constituent of the bark of the cinnamon tree and possesses broad-spectrum antimicrobial activity. In this study, we used best multiple linear regression (BMLR) to develop quantitative structure activity relationship (QSAR) models for cinnamaldehyde derivatives against wood-decaying fungi Trametes versicolor and Gloeophyllun trabeum. Based on the two optimal QSAR models, we then designed and synthesized two novel cinnamaldehyde compounds. The QSAR models exhibited good correlation coefficients: R²Tv = 0...
November 17, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27865616/phenylpropanoids-from-cinnamon-bark-reduced-%C3%AE-amyloid-production-by-the-inhibition-of-%C3%AE-secretase-in-chinese-hamster-ovarian-cells-stably-expressing-amyloid-precursor-protein
#7
Yu Jeong Kang, Dae-Gun Seo, So-Young Park
β-Amyloid (Aβ) is a substance of Alzheimer disease (AD), which is generated via the amyloidogenic pathway from amyloid precursor protein (APP) by β-secretase and γ-secretase. Inhibition of Aβ production is a potential therapeutic approach to AD. Thus, we tested the hypothesis that cinnamon bark (Cinnamomi Cortex Spissus), the dried bark of Cinnamomum cassia Blume (Lauraceae), and its constituents are beneficial to AD. The methanol extract of cinnamon bark efficiently reduced Aβ40 production in Chinese hamster ovarian (CHO) cells stably expressing APP as determined by enzyme-linked immunosorbent assay...
October 15, 2016: Nutrition Research
https://www.readbyqxmd.com/read/27864554/nostril-advantage-in-trigeminal-olfactory-perception-and-its-relation-to-handedness
#8
Simona Manescu, Benjhyna Daniel, Renée-Pier Filiou, Franco Lepore, Johannes Frasnelli
INTRODUCTION: Few studies investigated nostril-advantage in chemosensory perception, particularly, in relation to handedness. The aim of the present article was therefore to assess whether trigeminal/olfactory perception is altered by handedness. METHODS: We tested 50 (all right-handed) and 43 (22 left-handed) participants in Studies 1 and 2, respectively. We used binary mixtures of cinnamaldehyde and eucalyptol, in different proportions presented as physical mixtures (the same exact mixture presented birhinally to each nostril) or as a dichorhinic mixtures (different mixtures presented to each nostril)...
November 17, 2016: Perception
https://www.readbyqxmd.com/read/27832194/privacy-attitudes-among-early-adopters-of-emerging-health-technologies
#9
Cynthia Cheung, Matthew J Bietz, Kevin Patrick, Cinnamon S Bloss
INTRODUCTION: Advances in health technology such as genome sequencing and wearable sensors now allow for the collection of highly granular personal health data from individuals. It is unclear how people think about privacy in the context of these emerging health technologies. An open question is whether early adopters of these advances conceptualize privacy in different ways than non-early adopters. PURPOSE: This study sought to understand privacy attitudes of early adopters of emerging health technologies...
2016: PloS One
https://www.readbyqxmd.com/read/27830552/demonstrating-potential-of-cell-therapy-for-wilson-s-disease-with-the-long-evans-cinnamon-rat-model
#10
Fadi Luc Jaber, Yogeshwar Sharma, Sanjeev Gupta
Wilson's disease (WD) is characterized by the inability to excrete copper (Cu) from the body with progressive tissue injury, especially in liver and brain. The molecular defect in WD concerns mutations in ATP7B gene leading to loss of Cu transport from the hepatocyte to the bile canaliculus. While drugs, e.g., Cu chelators, have been available for several decades, these must be taken lifelong, which can be difficult due to issues of compliance or side effects. Many individuals may require liver transplantation, which can also be difficult due to donor organ shortages...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27788205/a-cinnamon-derived-procyanidin-compound-displays-anti-hiv-1-activity-by-blocking-heparan-sulfate-and-co-receptor-binding-sites-on-gp120-and-reverses-t-cell-exhaustion-via-impeding-tim-3-and-pd-1-upregulation
#11
Bridgette Janine Connell, Sui-Yuan Chang, Ekambaranellore Prakash, Rahima Yousfi, Viswaraman Mohan, Wilfried Posch, Doris Wilflingseder, Christiane Moog, Eiichi N Kodama, Pascal Clayette, Hugues Lortat-Jacob
Amongst the many strategies aiming at inhibiting HIV-1 infection, blocking viral entry has been recently recognized as a very promising approach. Using diverse in vitro models and a broad range of HIV-1 primary patient isolates, we report here that IND02, a type A procyanidin polyphenol extracted from cinnamon, that features trimeric and pentameric forms displays an anti-HIV-1 activity against CXCR4 and CCR5 viruses with 1-7 μM ED50 for the trimer. Competition experiments, using a surface plasmon resonance-based binding assay, revealed that IND02 inhibited envelope binding to CD4 and heparan sulphate (HS) as well as to an antibody (mAb 17b) directed against the gp120 co-receptor binding site with an IC50 in the low μM range...
2016: PloS One
https://www.readbyqxmd.com/read/27783121/raman-spectroscopy-electronic-microscopy-and-spme-gc-ms-to-elucidate-the-mode-of-action-of-a-new-antimicrobial-food-packaging-material
#12
Isabel Clemente, Margarita Aznar, Jesús Salafranca, Cristina Nerín
One critical challenge when developing a new antimicrobial packaging material is to demonstrate the mode of action of the antimicrobials incorporated into the packaging. For this task, several analytical techniques as well as microbiology are required. In this work, the antimicrobial properties of benzyl isothiocyanate, allyl isothiocyanate and essential oils of cinnamon and oregano against several moulds and bacteria have been evaluated. Benzyl isothiocyanate showed the highest antimicrobial activity and it was selected for developing the new active packaging material...
October 25, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27781067/quantitative-scrutinization-of-aflatoxins-in-different-spices-from-pakistan
#13
Narjis Naz, Aiza Kashif, Kinza Kanwal, Abdul Muqeet Khan, Mateen Abbas
The current research work aimed to access the contamination level of aflatoxins B1, B2, G1, and G2 in the household spices that are widely consumed in huge amounts. 200 different spice samples, 100 packed and 100 unpacked, were analyzed for the aflatoxins profile by HPLC with an incidence of 61.5% contamination out of which 53.66% samples exceed the EU limit. The results disclosed that the unpacked samples are more contaminated as compared to the packed samples except for white cumin seeds. Among packed and unpacked samples of spices, the maximum value of aflatoxins was detected in fennel, that is, 27...
2016: International Journal of Analytical Chemistry
https://www.readbyqxmd.com/read/27774415/cinnamon-extract-lowers-glucose-insulin-and-cholesterol-in-people-with-elevated-serum-glucose
#14
Richard A Anderson, Zhiwei Zhan, Rencai Luo, Xiuhua Guo, Qingqing Guo, Jin Zhou, Jiang Kong, Paul A Davis, Barbara J Stoecker
Cinnamon ( ròu guì) has in vitro insulin potentiating activity, and proanthocyanidins from cinnamon prevent in vitro formation of advanced glycation end products. Some human studies were equivocal, but several have shown beneficial effects of cinnamon supplementation on circulating glucose, lipids, and/or insulin. This placebo-controlled double-blind trial tested the effects of a dried water extract of cinnamon (Cinnamomum cassia) on circulating glucose, lipids, insulin, and insulin resistance. Men and women from Beijing and Dalian, China, were invited to participate if they had fasting serum glucose >6...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27771918/cinnamon-and-chronic-diseases
#15
Mitra Hariri, Reza Ghiasvand
Cinnamon (Cinnamomum zeylanicum and Cinnamon cassia), the eternal tree of tropical medicine, belongs to the Lauraceae family and is one of the most important spices used daily by people all over the world. It contains a lot of manganese, iron, dietary fiber, and calcium. Cinnamon contains derivatives, such as cinnamaldehyde, cinnamic acid, cinnamate, and numerous other components such as polyphenols and antioxidant, anti-inflammatory, antidiabetic, antimicrobial, anticancer effects. Several reports have dealt with the numerous properties of cinnamon in the forms of bark, essential oils, bark powder, and phenolic compounds, and each of these properties can play a key role in human health...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27768930/survey-for-the-presence-of-ascaridoid-larvae-in-the-cinnamon-flounder-pseudorhombus-cinnamoneus-temminck-schlegel-pleuronectiformes-paralichthyidae
#16
Liang Li, Jin-Yu Zhao, Hui-Xia Chen, Hui-Dong Ju, Meng An, Zhen Xu, Lu-Ping Zhang
The cinnamon flounder Pseudorhombus cinnamoneus is a frequently consumed marine fish in China. However, the occurrence of ascaridoid larvae in P. cinnamoneus remains unclear. In the present study, a total of 85 P. cinnamoneus caught from the Yellow Sea (off Shidao, 36°52'57″N, 122°26'42″E) in 2011, which is located between mainland China and the Korean Peninsula, was investigated for ascaridoid larval infection. Four ascaridoid larval types, including Anisakis type I of Berland (1961), Hysterothylacium type of Smith (1983), Hysterothylacium type HL of Guo et al...
October 14, 2016: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/27744281/primary-screening-of-plant-essential-oils-as-insecticides-fumigants-and-repellents-against-the-health-pest-paederus-fuscipes-coleoptera-staphylinidae
#17
Qiang Zhang, Xuan Wu, Zhiping Liu
The contact and fumigant toxicity as well as repellent activity of 10 plant essential oils were evaluated against Paederus fuscipes Curtis adults. Essential oils were identified through gas chromatography-mass spectrometry analysis. Results showed that wintergreen oil exhibited optimal contact and fumigant toxicity but had no significant repellent activity against P. fuscipes The LC50 values of fumigant toxicity of wintergreen oil were 2.680 and 1.591 µL/L air after 1 and 8 h of exposure, respectively...
October 15, 2016: Journal of Economic Entomology
https://www.readbyqxmd.com/read/27706951/inhibition-of-pancreatic-lipase-and-amylase-by-extracts-of-different-spices-and-plants
#18
Mohamed Sellami, Hanen Louati, Jannet Kamoun, Ali Kchaou, Mohamed Damak, Youssef Gargouri
The aim of this study is to search new anti-obesity and anti-diabetic agents from plant and spices crude extracts as alternative to synthetic drugs. The inhibitory effect of 72 extracts was evaluated, in vitro, on lipase and amylase activities. Aqueous extracts of cinnamon and black tea exhibited an appreciable inhibitory effect on pancreatic amylase with IC50 values of 18 and 87 μg, respectively. Aqueous extracts of cinnamon and mint showed strong inhibitory effects against pancreatic lipase with IC50 of 45 and 62 μg, respectively...
October 6, 2016: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/27706567/cinnamon-effectively-inhibits-the-activity-of-leukemia-stem-cells
#19
X Guan, M C Su, R B Zhao, H M Ouyang, X D Dong, P Hu, Q Pei, J Lu, Z F Li, C R Zhang, T-H Yang
Cinnamon is the main component of Sanyangxuedai, which is one of the effective traditional Chinese medicines for treating malignancies. Leukemia is a prevalent malignant disease that Sanyangxuedai has been used to treat. Although successful in several studies, there is a lack of solid evidence as to why Sanyangxuedai has an effect on leukemia, and little is known about the underlying mechanisms. In this study, the active ingredients of cinnamon were isolated, purified, and identified. The transwell transport pool formed with the Caco-2 cell model was used to filter the active ingredients of cinnamon by simulating the gastrointestinal barrier in vitro...
August 19, 2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27699851/cinnamon-sugar-scrub-dermatitis-natural-is-not-always-best
#20
Shehla Admani, Hannah Hill, Sharon E Jacob
Children are at risk of developing allergic contact dermatitis to fragrances. Personal hygiene products, even those labeled hypoallergenic or considered all natural, may be a significant source of fragrance exposure in this population.
October 4, 2016: Pediatric Dermatology
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