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https://www.readbyqxmd.com/read/27907042/role-of-platelet-parameters-on-neovascular-glaucoma-a-retrospective-case-control-study-in-china
#1
Shengjie Li, Wenjun Cao, Xinghuai Sun
PURPOSE: Retinal vein occlusion (RVO) and diabetic retinopathy (DR) are two major sight-threatening diseases which may lead to neovascular glaucoma (NVG). The aim of this study was to explore the association between platelet parameters and NVG. METHODS: A total of 185 subjects were enrolled for the study from January, 2012 to December, 2015 at the Eye-ENT Hospital of Fudan University. Patients include those with NVG secondary to RVO (RVO group, n = 38), patients with NVG secondary to DR (DR group, n = 47), diabetics mellitus without retinopathy (DM group, n = 52), and healthy individuals (control group, n = 48)...
2016: PloS One
https://www.readbyqxmd.com/read/27906814/prevalence-and-visual-outcome-of-glaucoma-with-uveitis-in-a-thai-population
#2
Kessara Pathanapitoon, Sarunya Smitharuck, Paradee Kunavisarut, Aniki Rothova
OBJECTIVE: The aim of this study was to report on the prevalence of uveitic secondary glaucoma (USG) and ocular hypertension in patients with uveitis in Thailand, and to identify factors associated with the development of USG and its visual outcome. DESIGN: This is a retrospective cohort study. METHODS: We included 174 consecutive uveitis patients (237 affected eyes) visiting the Ophthalmology Department of Chiang Mai University Hospital, Thailand, from January 2013 to March 2013...
November 30, 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27903184/microinvasive-tumor-endoresection-in-combination-with-ocular-stereotactic-radiosurgery
#3
Oleg A Sinyavskiy, Roman L Troyanovsky, Pavel I Ivanov, Alexandr S Golovin, Andrey V Tibilov, Svetlana N Solonina, Anna M Astapenko, Irina S Zubatkina
OBJECTIVE The use of Gamma Knife radiosurgery (GKRS) as monotherapy in the treatment of uveal melanoma (UM) allows clinicians to achieve high local tumor control with low recurrence but does not prevent secondary enucleation due to glaucoma in cases of large tumors. The authors analyzed indications for tumor endoresection (ER), the time interval between irradiation and surgery, and the features and results of performing ER for UM after GKRS. METHODS Thirty-seven patients between 28 and 78 years of age (16 male and 11 female patients) with UM underwent GKRS with a dose of 70 to 80 Gy that was applied to the center of the tumor with complete immobilization of the eye during the procedure...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27895936/neovascular-glaucoma-a-review
#4
REVIEW
Gustavo B Rodrigues, Ricardo Y Abe, Camila Zangalli, Savio L Sodre, Flavia A Donini, Danilo C Costa, Andre Leite, Joao P Felix, Marcelo Torigoe, Alberto Diniz-Filho, Homero Gusmão de Almeida
Neovascular glaucoma (NVG) is a secondary glaucoma generally associated with poor visual prognosis. The development of new vessels over the iris and the iridocorneal angle can obstruct aqueous humor outflow and lead to increased intraocular pressure. The underlying pathogenesis in most cases is posterior segment ischemia, which is most commonly secondary to proliferative diabetic retinopathy or central vein retinal occlusion. The neovascularization process in the eye is driven by the events that alter the homeostatic balance between pro-angiogenic factors, such as the vascular endothelial growth factor and anti-angiogenic factors, such as the pigment-epithelium-derived factor...
2016: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/27893525/outcomes-of-descemet-membrane-endothelial-keratoplasty-in-patients-with-previous-glaucoma-surgery
#5
Carolina Aravena, Fei Yu, Sophie X Deng
PURPOSE: To evaluate outcomes of Descemet membrane endothelial keratoplasty (DMEK) in eyes with previous trabeculectomy or a drainage device. METHODS: This is a retrospective study of 108 consecutive DMEK performed between October 2013 and December 2015. All eyes were divided into 3 groups: surgical treatment (ST) group, medical treatment (MT) group, and control group. Visual improvement, endothelial cell loss, and postoperative complications, including rejection, graft failure, and intraocular pressure elevation (≥25 mm Hg) were evaluated...
November 23, 2016: Cornea
https://www.readbyqxmd.com/read/27884546/-results-of-trabeculectomy-with-anti-vgef-therapy-in-the-treatment-of-neovascular-glaucoma-secondary-to-retinal-vein-occlusion-report-of-21%C3%A2-cases-followed-at-bukavu-eye-clinic-from-january-1%C3%A2-to-december-31th-2015
#6
T B Kabesha, D Kabesha, V Maloba, C Mwamba, B Chenge, A Mukalay
PURPOSE: To evaluate the results of anti-VGEF with trabeculectomy in the treatment of neovascular glaucoma, a severe complication of retinal vein occlusion (RVO). PATIENTS AND METHODS: This is a prospective case series of consecutive patients with neovascular glaucoma secondary to retinal vein occlusion. All patients underwent panretinal photocoagulation and a mean of 3 anti-VEGF injections prior to trabeculectomy. Ophthalmic parameters were recorded pre- and postoperatively: visual acuity (VA), intraocular pressure (IOP), iris examination, gonioscopy and fundus examination, and as necessary, fluorescein angiography...
November 21, 2016: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/27875487/microvascular-compromise-develops-following-nerve-fiber-layer-damage-in-normal-tension-glaucoma-without-choroidal-vasculature-involvement
#7
Eun Jung Lee, Sibum Kim, Sungsoon Hwang, Jong Chul Han, Changwon Kee
PURPOSE: To investigate capillary densities in patients with unilateral normal-tension glaucoma (NTG) and normal controls using optical coherence tomography-angiography. MATERIALS AND METHODS: We recruited 13 patients with unilateral NTG and 13 healthy controls. Optical coherence tomography-angiography was performed and pure peripapillary retinal capillary density was calculated after manually excluding large vessels and the optic disc. Paired comparison of capillary densities was performed among 3 categories of eye: NTG eye, fellow eye, and normal eye...
November 21, 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27872755/changes-in-anterior-segment-morphology-of-iris-bombe-before-and-after-laser-peripheral-iridotomy-in-patients-with-uveitic-secondary-glaucoma
#8
Wakako Ikegawa, Takashi Suzuki, Koji Namiguchi, Shiro Mizoue, Atsushi Shiraishi, Yuichi Ohashi
Purpose. To quantify changes in anterior segment (AS) parameters after laser peripheral iridotomy (LPI) using AS-optical coherence tomography (OCT) of iris bombe. Method. AS images of eight eyes were captured before and after iris bombe and more than 2 weeks after LPI (post-LPI) using AS-OCT. We compared the following AS parameters: anterior chamber depth (ACD), anterior chamber volume (ACV), iris curvature (IC), iris thickness at 500 μm from the scleral spur (IT-1) in the middle between the iris root and pupillary margin (IT-2) and 500 μm from the pupillary margin (IT-3) to the anterior chamber angle (ACA) (angle opening distance [AOD750]), and trabecular iris space area...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27862125/cases-of-advanced-visual-field-loss-at-referral-to-glaucoma-clinics-more-men-than-women
#9
David P Crabb, Luke J Saunders, Laura A Edwards
PURPOSE: In many medical conditions 'late presentation' of disease is more of a problem for men than women. Risk of sight loss from glaucoma is certainly greater in those detected with advanced disease. We performed a retrospective study to test the hypothesis that men are more likely than women to have advanced visual field loss at referral to glaucoma clinics. METHODS: We used 152 918 Humphrey visual fields from 32 147 patients from three regionally different hospitals in England; no other clinical data were made available apart from patient's age, sex and examination dates...
November 9, 2016: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/27861311/effect-of-trabeculotomy-on-corneal-endothelial-cell-loss-in-cases-of-postpenetrating-keratoplasty-glaucoma
#10
Ayaka Kusakabe, Naoki Okumura, Koichi Wakimasu, Kanae Kayukawa, Masami Kondo, Noriko Koizumi, Chie Sotozono, Shigeru Kinoshita, Kazuhiko Mori
PURPOSE: The aim of this study was to evaluate the effect of trabeculotomy (TLO) on glaucoma and endothelial cell loss after penetrating keratoplasty (PK). METHODS: A retrospective study was conducted on consecutive patients who underwent PK and in whom more than 24 months of follow-up was available. Patients were categorized into the PK+TLO group [ie, TLO for post-PK glaucoma (n = 10)] and the PK group [PK alone (n = 73)]. Intraocular pressure (IOP) was evaluated during each follow-up examination...
November 16, 2016: Cornea
https://www.readbyqxmd.com/read/27860168/use-of-a-350-mm-2-baerveldt-glaucoma-drainage-device-to-maintain-vision-and-control-intraocular-pressure-in-dogs-with-glaucoma-a-retrospective-study-2013-2016
#11
Kathleen L Graham, David Donaldson, Francis A Billson, F Mark Billson
OBJECTIVE: To evaluate the 350-mm(2) Baerveldt glaucoma drainage device (GDD) in dogs with refractory glaucoma when modifications to address postoperative hypotony (extraluminal ligature; intraluminal stent) and the fibroproliferative response (intraoperative Mitomycin-C; postoperative oral colchicine and prednisolone) are implemented as reported in human ophthalmology. DESIGN: Retrospective case series. ANIMALS: Twenty-eight client-owned dogs (32 eyes) including seven dogs (nine eyes) with primary glaucoma and 21 dogs (23 eyes) with secondary glaucoma...
November 16, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27849312/oct-angiography-of-the-peripapillary-retina-in-primary-open-angle-glaucoma
#12
Eun Ji Lee, Kyoung Min Lee, Seung Hyen Lee, Tae-Woo Kim
Purpose: The purpose of this study was to investigate the topographic relationship between the decreased parapapillary retinal microvasculature as assessed by optical coherence tomography angiography (OCTA) and retinal nerve fiber layer (RNFL) defect in eyes with primary open-angle glaucoma (POAG) and a localized RNFL defect. Methods: The peripapillary retinal circulation was evaluated using the OCTA centered on the optic nerve head in 98 POAG eyes having a localized RNFL defect and 45 healthy control eyes...
November 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27844100/-secondary-diseases-in-high-myopia
#13
F Ziemssen, W Lagrèze, B Voykov
BACKGROUND: Eyes with high myopia (axial length ≥ 26.5 mm) do not just have a different size. Due to morphological and structural changes there is a considerably increased risk for many different secondary diseases. OBJECTIVE: Determination of the incidence and mortality in high myopia, discussion of effects and clinical signs, presentation of treatment recommendations and counselling. MATERIAL AND METHODS: A systematic search of the literature was carried out and a discussion on basic principles and epidemiological investigations is presented...
November 14, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27834964/a-review-of-145%C3%A2-234-ophthalmic-patient-episodes-lost-to-follow-up
#14
A Davis, A Baldwin, M Hingorani, A Dwyer, D Flanagan
PurposeLost to follow-up and delays in follow-up care are a major problem in chronic diseases, particularly when irreversible progression precedes symptoms. The NPSA Glaucoma Safety Alert in 2009 highlighted the risk and requirements for consistent robust review systems in ophthalmology. In response, Moorfields Eye Hospital reviewed the records of all patients in all subspecialties without review appointments booked. The purpose of this study was to determine whether ophthalmic patients lost to follow-up had come to harm and develop investigation techniques to optimise safety, which do not put excessive demands on clinical staff time...
November 11, 2016: Eye
https://www.readbyqxmd.com/read/27828849/preliminary-results-of-co2-laser-assisted-sclerectomy-surgery-class-in-the-treatment-of-advanced-glaucoma-in-a-chinese-population
#15
Doris W F Yick, Jacky W Y Lee, Susanna Tsang, Barry Y M Yeung, Can Y F Yuen
To evaluate the efficacy and safety of CO2 laser-assisted sclerectomy surgery (CLASS) in Chinese patients with advanced glaucoma.Patients with advanced glaucoma who were candidates for glaucoma filtration surgery were included. The intraocular pressure (IOP) and number of antiglaucoma medications were documented before surgery and at all postoperative clinic visits. All intra- and postoperative complications were documented. The primary outcome measures were the changes in IOP and medication use before and after the procedure as well as complications from the procedure...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27815676/-recovery-time-as-a-potential-new-progression-parameter-for-patients-with-advanced-glaucomatous-optic-atrophy
#16
B Hohberger, S Mißlinger, F Horn, J Kremers
BACKGROUND: Functional tests in glaucoma diagnosis can monitor a potential perimetric progression. However white-on-white perimetry is limited in advanced glaucoma, whereas contrasts were detected reproducibly. Especially when stressing (i. e. adapting) the visual system, subsequent measurements yielded different results-the visual system needs a "recovery time". In the present study the recovery time was investigated in patients with advanced glaucoma. Additionally correlation analysis was done with standard perimetric parameters...
November 4, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27815624/contralateral-eye-comparison-study-in-mics-migs-trabectome%C3%A2-vs-istent-inject%C3%A2
#17
Johannes Gonnermann, Eckart Bertelmann, Milena Pahlitzsch, Anna-Karina B Maier-Wenzel, Necip Torun, Matthias K J Klamann
PURPOSE: To compare the safety and efficacy profile after combined micro-incision cataract surgery (MICS) and micro-invasive glaucoma surgery (MIGS) with the ab interno trabeculectomy (Trabectome®) in one eye versus two iStent® inject devices in the contralateral eye in patients with open-angle glaucoma (OAG) and cataract. METHODS: This retrospective, intraindividual eye comparison study included 27 patients (54 eyes) who were treated with combined MICS and ab interno trabeculectomy (group I, Trabectome®) in one eye and two iStent® inject devices (group II, GTS 400) in the fellow eye...
November 4, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27811562/outcomes-of-descemet-stripping-automated-endothelial-keratoplasty-in-toxic-anterior-segment-syndrome-after-phacoemulsification
#18
Manpreet Kaur, Jeewan S Titiyal, Ruchita Falera, Tarun Arora, Namrata Sharma
PURPOSE: To evaluate the visual and anatomical outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK) in patients with toxic anterior segment syndrome (TASS). METHODS: Fourteen eyes of 14 patients who underwent clear corneal DSAEK for endothelial decompensation secondary to TASS after phacoemulsification were included in this prospective study. Intraoperative surgical difficulties were noted. Preoperative and postoperative evaluation of visual acuity, slit-lamp examination, intraocular pressure, central corneal thickness, and endothelial count was performed in all cases...
November 2, 2016: Cornea
https://www.readbyqxmd.com/read/27800258/secondary-glaucoma-associated-with-encircling-scleral-buckle-migration-into-the-cornea
#19
Şengül Özdek, Murat Hasanreisoğlu, Ufuk Adıgüzel, Zeynep Aktaş
Transmuscular migration of the encircling band through rectus muscles and straddling of the cornea has only been reported in a few cases previously in the literature. This rare condition has never been associated with glaucoma. In this report, we aimed to describe a unique case with transmuscular migration of encircling buckle as a probable cause of glaucoma. A 17-year-old female presented with transmuscular migration of buckle and high intraocular pressure (IOP). Limbal/corneal migration of the silicone band was thought to be the main reason for the IOP rise; therefore, scleral band removal was performed...
January 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27800256/transpupillary-argon-laser-cyclophotocoagulation-in-a-refractory-traumatic-glaucoma-patient-with-aphakia-and-aniridia
#20
Umut Duygu Uzunel, Berna Yüce, Tuncay Küsbeci, Halil Ateş
We present a case of transpupillary argon laser cyclophotocoagulation (TALC) in a patient with traumatic aniridia and aphakia secondary to blunt trauma who had previous bilateral trabeculectomy. Four months after the trauma the patient's intraocular pressure (IOP) rose to 35 mmHg despite topical antiglaucomatous medication. Inferior 180 degrees cyclophotocoagulation was performed with transpupillary argon laser in the first session and his IOP fell to values of 12-17 mmHg. Twelve weeks after TALC, his IOP rose to 22 mmHg and we had to apply TALC to the residual ciliary processes...
January 2016: Turkish Journal of Ophthalmology
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