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https://www.readbyqxmd.com/read/29675390/childhood-glaucoma-profile-in-dakahelia-egypt-a-retrospective-study
#1
Tharwat H Mokbel, Eman M El Hefney, Sherein M Hagras, Ahmed A ALNagdy, Amani E Badawi, Manal A Kasem, Shereen M El Shaer
AIM: To analyze childhood glaucoma regarding its demographics, presentations, different causes and surgical modalities used among patients in Dakahelia and to apply the Childhood Glaucoma Research Network (CGRN) classification retrospectively to evaluate its convenience. METHODS: A retrospective study in which the medical files of all glaucoma patients <16 years old presented to Mansoura Ophthalmic Center, Mansoura University from 2014 to 2017, were retrieved and analyzed...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29675383/clinical-outcomes-of-patterned-laser-trabeculoplasty-as-adjuvant-therapy-in-open-angle-glaucoma-and-ocular-hypertension
#2
Gustavo Espinoza, Leonardo Castellanos, Ignacio Rodriguez-Una, Paul Anthony Camacho, Juan Camilo Parra
AIM: To assess the efficacy and safety of patterned laser trabeculoplasty (PLT) as an adjunctive treatment in open angle glaucoma (OAG) or ocular hypertension (OHT) patients who were under antiglaucoma medical treatment. METHODS: This study was a retrospective review of primary or secondary OAG patients and OHT patients with medically uncontrolled (≥18 mm Hg) intraocular pressure (IOP) who underwent 360° PLT from June 2016 to August 2016. Follow-up visits at week 1, and 1, 3 and 6mo were performed...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29675382/long-term-outcomes-of-uveitic-glaucoma-treated-with-ahmed-valve-implant-in-a-series-of-chinese-patients
#3
Ning Bao, Zheng-Xuan Jiang, Paul Coh, Li-Ming Tao
AIM: To report long-term outcomes of secondary glaucoma due to uveitis treated with Ahmed glaucoma valve (AGV) implantation in a series of Chinese patients. METHODS: The retrospective study included 67 eyes from 56 patients with uveitic glaucoma who underwent AGV implantation. Success of the treatment was defined as patients achieving intraocular pressure (IOP) levels between 6 and 21 mm Hg with or without additional anti-glaucoma medications and/or a minimum of 20% reduction from baseline IOP...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29675026/multiplex-cytokine-analysis-of-aqueous-humor-in-juvenile-idiopathic-arthritis-associated-anterior-uveitis-with-or-without-secondary-glaucoma
#4
Dirk Bauer, Maren Kasper, Karoline Walscheid, Jörg M Koch, Philipp S Müther, Bernd Kirchhof, Arnd Heiligenhaus, Carsten Heinz
Patients with juvenile idiopathic arthritis often develop chronic anterior uveitis (JIAU). JIAU patients possess a particularly high risk for developing secondary glaucoma when inflammatory inactivity has been achieved. By using multiplex bead assay analysis, we assessed levels of pro- and anti-inflammatory cytokines, chemokines, or metalloproteinases in the aqueous humor (AH) of patients with clinically inactive JIAU with (JIAUwG) or without secondary glaucoma (JIAUwoG), or from patients with senile cataract as controls...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29651348/dna-methylation-status-of-the-interspersed-repetitive-sequences-for-line-1-alu-herv-e-and-herv-k-in-trabeculectomy-specimens-from-glaucoma-eyes
#5
Sunee Chansangpetch, Sasiprapa Prombhul, Visanee Tantisevi, Pimpayao Sodsai, Anita Manassakorn, Nattiya Hirankarn, Shan C Lin
Background/Aims: Epigenetic mechanisms via DNA methylation may be related to glaucoma pathogenesis. This study aimed to determine the global DNA methylation level of the trabeculectomy specimens among patients with different types of glaucoma and normal subjects. Methods: Trabeculectomy sections from 16 primary open-angle glaucoma (POAG), 12 primary angle-closure glaucoma (PACG), 16 secondary glaucoma patients, and 10 normal controls were assessed for DNA methylation using combined-bisulfite restriction analysis...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29644538/a-review-of-the-clinical-usefulness-of-selective-laser-trabeculoplasty-in-exfoliative-glaucoma
#6
REVIEW
Andreas Katsanos, Anastasios G Konstas, Dimitrios G Mikropoulos, Luciano Quaranta, Irini C Voudouragkaki, Georgios P Athanasopoulos, Ioannis Asproudis, Miguel A Teus
In the last decade, selective laser trabeculoplasty (SLT) has been commonly used in the management of several different types of glaucoma, as either primary or adjunct therapy. The technique has an excellent safety profile and is at least as effective as argon laser trabeculoplasty. Although the actual mechanism of action of SLT remains unclear, evidence has shown that it does not induce morphologically evident trabecular meshwork alterations. SLT's non-disruptive mode of action offers the advantage of repeatability...
April 11, 2018: Advances in Therapy
https://www.readbyqxmd.com/read/29643776/patch-grafting-using-an-ologen-collagen-matrix-to-manage-tubal-exposure-in-glaucoma-tube-shunt-surgery
#7
Masaki Tanito, Ichiya Sano, Yoshifumi Ikeda, Etsuko Fujihara
Purpose: To report the results using an ologen Collagen Matrix as a patch graft in eyes with tubal exposure after tube shunt surgery. Case Reports: Case 1 was an 82-year-old man with tubal exposure in his right eye 26 months after receiving a Baerveldt glaucoma implant. The tube was covered by surrounding conjunctival tissue combined with subconjunctival placement of an ologen Collagen Matrix as a patch graft. Two years after implantation, the tube was not exposed...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29620670/effectiveness-of-multiple-therapeutic-strategies-in-neovascular-glaucoma-patients-a-prisma-compliant-network-meta-analysis
#8
Zixian Dong, Jianyang Gong, Rongfeng Liao, Shaojun Xu
PURPOSE: Neovascular glaucoma (NVG) is a severe secondary glaucoma with uncontrolled intraocular pressure that leads to serious eye pain and vision loss. Presently, the therapeutic strategies for NVG are diverse, but the therapeutic effects are still not ideal. We performed a network analysis to assess the effect of multiple therapeutic strategies on the treatment of NVG patients. METHODS: We searched public electronic databases through April 2017 using the following keywords "neovascular glaucoma," "iris neovascularization," "hemorrhagic glaucoma," and "random" without language restrictions...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29620183/puerarin-regulates-neovascular-glaucoma-through-pigment-epithelium%C3%A2-derived-growth-factor%C3%A2-induced-nf%C3%A2-%C3%AE%C2%BAb-signaling-pathway
#9
Hui-Yu Wei, Ya-Jie Zhang, Shao-Zhen Zhao
Neovascular glaucoma is an ophthalmic disease and a potentially blinding secondary glaucoma caused by the formation of abnormal new blood vessels on the iris, which can prevent the normal drainage of water from the anterior segment of the eye. Evidence from China has suggested that puerarin benefits many diseases including myocardial infarction, stable angina, cerebral ischemia and glaucoma in a clinical setting. In the present study, the aim was to investigate the efficacies of puerarin on neovascular glaucoma in a mouse model...
March 28, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29615172/comparison-of-mean-corneal-endothelial-cell-loss-after-trabeculectomy-with-and-without-mitomycin-c
#10
Muhammad Shaheer, Arooj Amjad, Nasir Ahmed
OBJECTIVE: To compare mean endothelial cell loss in patients of primary open angle glaucoma undergoing trabeculectomy with and without mitomycin C. STUDY DESIGN: Randomised control study. PLACE AND DURATION OF STUDY: Institute of Ophthalmology, Mayo Hospital, Lahore, from May 2016 to April 2017. METHODOLOGY: Patients with primary open angle glaucoma, not controlled with medication, were selected from the outpatient department...
April 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29613981/phacomorphic-angle-closure-following-silicone-oil-tamponade-in-a-pediatric-patient
#11
Victoria C Leung, Simon Fung, Rajeev Muni, Asim Ali
PURPOSE: To report a case of phacomorphic glaucoma following retinal detachment repair with silicone oil in a pediatric patient. STUDY DESIGN: Case report. METHODS: A chart review was conducted at St. Michael's Hospital and The Hospital for Sick Children (Toronto, Canada), where the patient received ophthalmic care from July 28, 2015 onwards. RESULTS: A 14 year-old boy with a history of traumatic retinal detachment and proliferative vitreoretinopathy in the left eye, requiring two pars plana vitrectomies, membrane peel, and silicone oil tamponade, presented with one-day history of decreased vision in the left eye, severe headache, nausea, and vomiting...
April 2, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29613980/use-of-intravitreal-bevacizumab-for-the-treatment-of-secondary-glaucoma-due-to-metastatic-iris-tumor
#12
Rukiye Aydin, Tongalp H Tezel
PURPOSE: To report the efficacy of intravitreal bevacizumab to resolve secondary angle closure glaucoma caused by biliary tract carcinoma metastasis to iris. ABSTRACT: A 52-year-old Caucasian woman who was under systemic chemotherapy for biliary tract carcinoma presented with metastatic tumor in the left iris. At presentation, her visual acuity was at 20/50 level. Tumor was occupying nasal half of the iris and had already occupied 5.5 clock hours of the angle resulting intraocular pressure elevation to 34▒mm Hg...
April 2, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29613978/gonioscopy-assisted-transluminal-trabeculotomy-an-ab-interno-circumferential-trabeculotomy-24-month-follow-up
#13
Davinder S Grover, Oluwatosin Smith, Ronald L Fellman, David G Godfrey, Aditi Gupta, Ildamaris Montes de Oca, William J Feuer
PURPOSE: Provide 24-month follow up on surgical success and safety of an ab interno circumferential 360-degree trabeculotomy. PATIENTS AND METHODS: Chart review of patients who underwent a GATT procedure by 4 of the authors (D.S.G., O.S., R.L.F., D.G.G.). The surgery was performed in adults with various open-angle glaucomas with pre-operative intraocular pressures (IOP) of ≥18▒mm Hg. RESULTS: 198 patients aged 24-89 years underwent the GATT procedure with at least 18 months follow-up...
April 2, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29610849/temporary-piggyback-intraocular-lens-implantation-versus-single-intraocular-lens-implantation-in-congenital-cataracts-long-term-clinical-outcomes
#14
Sungsoon Hwang, Dong Hui Lim, Soomin Lee, Daye Diana Choi, Eui-Sang Chung, Tae-Young Chung
Purpose: To report the long-term results of temporary piggyback IOL implantation in congenital cataract and to compare the clinical outcomes of temporary piggyback IOL with those of single IOL implantation. Methods: This is a retrospective, comparative, interventional study. The medical records of all consecutive patients who underwent cataract extraction and single or temporary piggyback IOL implantation within the first 3 years of life from 1999 to 2013 at Samsung Medical Center were reviewed...
April 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29610523/physical-activity-visual-impairment-and-eye-disease
#15
REVIEW
Sharon R Ong, Jonathan G Crowston, Paul D Loprinzi, Pradeep Y Ramulu
Numerous studies have demonstrated physical activity is a strong factor in overall health and well-being, and a growing body of literature, reviewed herein, suggests that several eye conditions, including glaucoma, age-related macular degeneration, and diabetic retinopathy, are associated with lower activity levels. Likewise, physical activity levels are lower in persons with worse vision. Research in this area has utilized both self-reported physical activity measures as well as objective measures of activity (i...
April 3, 2018: Eye
https://www.readbyqxmd.com/read/29607552/pathophysiology-and-management-of-glaucoma-associated-with-phakomatoses
#16
REVIEW
Alisa T Thavikulwat, Deepak P Edward, Abdulrahman AlDarrab, Thasarat S Vajaranant
The phakomatoses, encephalotrigeminal angiomatosis (ETA; Sturge-Weber Syndrome), neurofibromatosis type 1 (NF1 or von Recklinghausen disease), Von Hippel-Lindau (VHL) disease, tuberous sclerosis (TSC), oculodermal melanocytosis (ODM), and phakomatosis pigmentovascularis are a group of neurocutaneous disorders that have characteristic systemic and ocular manifestations. Through many different mechanisms, they may cause glaucomatous damage of the optic nerve and subsequent vision loss varying from mild to severe...
April 1, 2018: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/29607217/modern-diagnostic-techniques-for-the-assessment-of-ocular-blood-flow-in-myopia-current-state-of-knowledge
#17
REVIEW
Ewa Grudzińska, Monika Modrzejewska
Myopia is the most common refractive error and the subject of interest of various studies assessing ocular blood flow. Increasing refractive error and axial elongation of the eye result in the stretching and thinning of the scleral, choroid, and retinal tissues and the decrease in retinal vessel diameter, disturbing ocular blood flow. Local and systemic factors known to change ocular blood flow include glaucoma, medications and fluctuations in intraocular pressure, and metabolic parameters. Techniques and tools assessing ocular blood flow include, among others, laser Doppler flowmetry (LDF), retinal function imager (RFI), laser speckle contrast imaging (LSCI), magnetic resonance imaging (MRI), optical coherence tomography angiography (OCTA), pulsatile ocular blood flowmeter (POBF), fundus pulsation amplitude (FPA), colour Doppler imaging (CDI), and Doppler optical coherence tomography (DOCT)...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29602960/impact-of-same-session-trabectome-surgery-on-ahmed-glaucoma-valve-outcomes
#18
Hamed Esfandiari, Tarek Shazly, Priyal Shah, Kiana Hassanpour, Pooya Torkian, Mehdi Yaseri, Nils A Loewen
PURPOSE: To evaluate the efficacy and survival rates of same session ab interno trabeculectomy with the trabectome and Ahmed glaucoma valve implant (AT) in comparison to the Ahmed glaucoma valve alone (A). METHOD: A total of 107 eyes undergoing primary glaucoma surgery were enrolled in this retrospective comparative case series, including 48 eyes which underwent AT and 59 eyes which received A alone. Participants were identified using the procedural terminology codes, and their medical records were reviewed...
March 30, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29592533/istent-inject-as-a-reasonable-alternative-procedure-following-failed-trabeculectomy
#19
Anja-Maria Davids, Milena Pahlitzsch, Alexander Boeker, Necip Torun, Eckart Bertelmann, Anna-Karina Maier-Wenzel, Annette Hager, Johannes Gonnermann, Matthias Klamann
PURPOSE: The aim of this study is to assess the intraocular pressure lowering effect and the performance of the glaucoma therapy of the iStent inject in glaucoma patients with uncontrolled intraocular pressure after failed trabeculectomy. METHODS: In this retrospective study, iStent inject implantation (Glaukos Corporation, Laguna Hills, CA, USA) was performed in 22 eyes of 21 subjects suffering from glaucoma (n = 18 primary open angle glaucoma, n = 3 pseudoexfoliation glaucoma, and n = 1 for secondary glaucoma) with an intraocular pressure above target pressure after failed trabeculectomy (mean = 9...
March 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29590684/-morphological-and-quantitative-changes-in-retinal-and-optic-nerve-vessels-in-experimental-glaucoma-model-with-elevated-iop-for-7-weeks
#20
Carolina Mann, Fabian Anders, Hanhan Liu, Katrin Brockhaus, Aiwei Liu, Franz H Grus, Norbert Pfeiffer, Solon Thanos, Verena Prokosch
INTRODUCTION: Glaucoma is characterised by progressive loss of retinal ganglion cells and axons. Experimental research has concentrated on understanding the pathophysiological mechanisms involved in glaucomatous damage. It is still a matter of debate whether neurons or capillaries are primarily damaged by elevated intraocular pressure (IOP). The aim of this study was to detect IOP-induced vascular changes in the vessels of the optic nerve head and the main vessels of the retina in vivo...
March 28, 2018: Klinische Monatsblätter Für Augenheilkunde
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