Yilei Ma, Jia Yi, Jing Ruan, Jiahui Ma, Qinsi Yang, Kun Zhang, Maolan Zhang, Guoming Zeng, Libo Jin, Xiaobei Huang, Jianshu Li, Haifeng Yang, Wei Wu, Da Sun
Gliomas, the most prevalent primary brain tumors, pose considerable challenges due to their heterogeneity, intricate tumor microenvironment (TME), and blood-brain barrier (BBB), which restrict the effectiveness of traditional treatments like surgery and chemotherapy. This review provides an overview of engineered cell membrane technologies in glioma therapy, with a specific emphasis on targeted drug delivery and modulation of the immune microenvironment. This study investigates the progress in engineered cell membranes, encompassing physical, chemical, and genetic alterations, to improve drug delivery across the BBB and effectively target gliomas...
April 23, 2024: Advanced Healthcare Materials