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https://www.readbyqxmd.com/read/28096041/advance-care-planning-in-adults-with-congenital-heart-disease-a-patient-priority
#1
Lisa X Deng, Lacey P Gleason, Abigail M Khan, David Drajpuch, Stephanie Fuller, Leah A Goldberg, Christopher E Mascio, Sara L Partington, Lynda Tobin, Yuli Y Kim, Adrienne H Kovacs
BACKGROUND: Adult congenital heart disease (ACHD) patients with moderate or great defect complexity are at risk for premature death. Although early engagement in advance care planning (ACP) is recommended, previous research suggests that it seldom occurs. METHODS: This study investigated ACHD patient preferences for ACP and factors that impact preferences. ACHD patients completed an ACP preferences questionnaire, the Hospital Anxiety and Depression Scale and a measure of attachment styles...
January 4, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28092429/residents-understanding-of-adult-congenital-heart-disease
#2
Paul Cooper, Morgan Hindes, Timothy M Maul, Stephen C Cook
OBJECTIVE: Medical residents are exposed to increasing numbers of adults with congenital heart disease (ACHD). While inadequate ACHD knowledge may lead to inappropriate practice, this educational deficit has not been investigated. Our aim was to analyze residents' attitudes, perceived ability, and knowledge of ACHD medicine. DESIGN, METHODS, OUTCOME MEASURES: A single center, multiprogram cross-sectional study was conducted in 2015 using an electronic survey to assess 472 medical residents' perceived knowledge and self-assessed skills related to ACHD medicine...
January 16, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28091794/the-impact-of-liver-disorders-on-perioperative-management-of-reoperative-cardiac-surgery-a-retrospective-study-in-adult-congenital-heart-disease-patients
#3
Koko Adachi, Hiroaki Toyama, Yu Kaiho, Osamu Adachi, Hiroto Hudeta, Masanori Yamauchi
PURPOSE: We evaluated the preoperative prevalence of risk factors for liver disorders and the relationship between the liver disorders and perioperative outcomes in adult congenital heart disease (ACHD) patients. METHODS: This retrospective study included 32 ACHD patients who underwent reoperative cardiac surgery. RESULTS: Preoperatively, 38% of the study patients had risk factors, including congestive liver (CL) due to right heart failure (31%), chronic hepatitis C (HC) (22%), and both CL and HC (16%)...
January 16, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28087052/contraceptive-practices-of-women-with-complex-congenital-heart-disease
#4
Pamela D Miner, Mary M Canobbio, Dorothy D Pearson, Mary Schlater, Yvonne Balon, Kathryn J Junge, Ami Bhatt, Deena Barber, Michelle J Nickolaus, Adrienne H Kovacs, Philip Moons, Kate Shaw, Susan M Fernandes
Understanding the contraceptive practices of women with complex congenital heart disease (CHD) and providing them individualized contraception counseling may prevent adverse events and unplanned high-risk pregnancies. Given this, we sought to examine the contraceptive practices in women with CHD, describe adverse events associated with contraceptive use, and describe the provision of contraception counseling. Women >18 years were recruited from 2011 to 2014 from 9 adult CHD (ACHD) centers throughout North America...
December 18, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/28072626/acquired-coronary-artery-disease-in-adult-patients-with-congenital-heart-disease-a-true-or-a-false-problem
#5
Alessandro Giamberti, Mauro Lo Rito, Erika Conforti, Alessandro Varrica, Mario Carminati, Alessandro Frigiola, Lorenzo Menicanti, Massimo Chessa
BACKGROUND: The population of adults with congenital heart disease (ACHD) is increasing and aging, and a large percentage of this population is now over 65 years of age. For this reason, it is probable that acquired coronary artery disease (CAD) will become an important issue that needs to be addressed also in these patients. We retrospectively analyzed all ACHD patients who underwent surgery in our Institution with the aim to investigate the incidence of associated CAD and the results of surgical treatment...
January 7, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28065906/incidence-risk-factors-and-predictors-of-infective-endocarditis-in-adult-congenital-heart-disease-focus-on-the-use-of-prosthetic-material
#6
Joey M Kuijpers, Dave R Koolbergen, Maarten Groenink, Kathinka C H Peels, Constant L A Reichert, Marco C Post, Hans A Bosker, Elly M C J Wajon, Aeilko H Zwinderman, Barbara J M Mulder, Berto J Bouma
AIMS: Adult congenital heart disease (ACHD) predisposes to infective endocarditis (IE). Surgical advancements have changed the ACHD population, whereas associated prosthetic material may constitute additional IE targets. We aimed to prospectively determine contemporary incidence, risk factors, and predictors of IE in a nationwide ACHD cohort, focusing on the presence of prosthetics. METHODS AND RESULTS: We identified 14 224 patients prospectively followed in the CONCOR ACHD registry (50...
January 8, 2017: European Heart Journal
https://www.readbyqxmd.com/read/27931725/body-weights-in-adults-with-congenital-heart-disease-and-the-obesity-frequency
#7
Joseph B Lerman, Ira A Parness, Rajesh U Shenoy
Obesity may associate with greater cardiovascular risk in adults with congenital heart disease (ACHD) than in the general population. As ACHD often have exercise limitations, they may be uniquely predisposed to obesity. Nevertheless, obesity prevalence in ACHD, compared with the general population, has not been quantified in a large US cohort. Hence, we sought to determine the prevalence of obesity (30 ≤ body mass index <40) and morbid obesity (body mass index ≥40), in a large cohort of ACHD, compared with matched controls...
November 16, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27878778/elevated-serum-levels-of-ghrelin-and-tnf-%C3%AE-in-patients-with-cyanotic-and-acyanotic-congenital-heart-disease
#8
Sai Zhang, Gong-Liang Guo, Li-Li Yang, Li-Qun Sun
BACKGROUND: The levels of ghrelin and tumor necrosis factor alpha (TNF-α) are considered biological markers of congenital heart diseases (CHD). The present meta-analysis was conducted to investigate the clinical significance of serum levels of ghrelin and TNF-α in children with (CHD). METHODS: Chinese and English scientific literature databases were searched to retrieve published studies relevant to ghrelin, TNF-α and CHD. Manual search was additionally employed to identify other relevant studies from cross-references...
November 23, 2016: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/27836946/heart-transplantation-in-adult-congenital-heart-disease
#9
REVIEW
Luke J Burchill
Heart failure (HF) in adult congenital heart disease (ACHD) is vastly different to that observed in acquired heart disease. Unlike acquired HF in which pharmacological strategies are the cornerstone for protecting and improving ventricular function, ACHD-related HF relies heavily upon structural and other interventions to achieve these aims. patients with ACHD constitute a small percentage of the total adult heart transplant population (∼3%), although the number of ACHD heart transplant recipients is growing rapidly with a 40% increase over the last two decades...
December 1, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27834768/design-and-implementation-of-a-prospective-adult-congenital-heart-disease-biobank
#10
Alexander R Opotowsky, Brittani Loukas, Christina Ellervik, Lilamarie E Moko, Michael N Singh, Elizabeth I Landzberg, Eric B Rimm, Michael J Landzberg
BACKGROUND: Adults with congenital heart disease (ACHD) comprise a growing, increasingly complex population. The Boston Adult Congenital Heart Disease Biobank is a program for the collection and storage of biospecimens to provide a sustainable resource for scientific biomarker investigation in ACHD. METHODS: We describe a protocol to collect, process, and store biospecimens for ACHD or associated diagnoses developed based on existing literature and consultation with cardiovascular biomarker epidemiologists...
November 2016: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/27832613/prognostic-value-of-n-terminal-pro-b-type-natriuretic-peptide-troponin-t-and-growth-differentiation-factor-15-in-adult-congenital-heart-disease
#11
Vivan J Baggen, Annemien van den Bosch, Jannet A Eindhoven, Anne-Rose Schut, Judith A A E Cuypers, Maarten Witsenburg, Monique de Waart, Ron H van Schaik, Felix Zijlstra, Eric Boersma, Jolien W Roos-Hesselink
BACKGROUND: -The number of patients with adult congenital heart disease (ACHD) is rapidly increasing. In order to optimize patient management, there is a great need to accurately identify high-risk patients. Still, no biomarker has been firmly established as a clinically useful prognostic tool in this group. We studied the association of N-terminal pro-B-type natriuretic peptide (NT-proBNP), high-sensitive troponin-T (hs-TnT) and growth-differentiation factor 15 (GDF-15) with cardiovascular events in ACHD...
November 3, 2016: Circulation
https://www.readbyqxmd.com/read/27738072/surgery-for-supraventricular-tachycardia-and-congenital-heart-defects-long-term-efficacy-of-the-combined-approach-in-adult-patients
#12
Alessandro Giamberti, Francesca R Pluchinotta, Massimo Chessa, Alessandro Varrica, Raffaele Vitale, Alessandro Frigiola, Carlo Pappone, Marco Ranucci
AIMS: Supraventricular arrhythmias are a major cause of morbidity and mortality in adult patients with congenital heart disease (CHD). Intraoperative ablation offers an alternative for patients who failed ablation procedures or are requiring concomitant surgical intervention. We present our long-term results with the surgical treatment of arrhythmias in adults with CHD (ACHD) undergoing elective cardiac surgery and the clinical predictors for arrhythmia recurrence. METHODS AND RESULTS: Between 2002 and 2013, 80 consecutive patients with CHD, mean age of 39 years, underwent intraoperative ablation with monopolar irrigated radiofrequency during cardiac surgery procedures...
October 12, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/27642135/pulmonary-arterial-hypertension-in-congenital-heart-disease-current-perspectives-and-future-challenges
#13
George Giannakoulas, Michael A Gatzoulis
Medical and scientific research in the field of pulmonary arterial hypertension (PAH) in adults with congenital heart disease (ACHD) has gradually become globalized, inclusive and collaborative over the past few years. The education of physicians, health administrators and patients on congenital heart disease (CHD), specifically in the field of PAH, is of paramount importance. It is also crucial for ACHD patients with PAH to be followed in tertiary centers and to benefit from a multidisciplinary approach. Shared care models dictate a closer collaboration between tertiary expert centers and local non-specialist services, as well as networking between expert physicians in CHD and PAH and geneticists/epidemiologists, with the inclusion of PAH-CHD patients in national and international registries with a detailed genotypic/phenotypic characterization...
August 20, 2016: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/27634029/short-term-costs-and-hospitalization-rates-in-patients-with-adult-congenital-heart-disease-after-pulmonic-valve-replacement
#14
Deana Mikhalkova, Eric Novak, Ari Cedars
In the adult congenital heart disease (ACHD) population, pulmonary valve replacement (PVR) is a common intervention, its benefit, however, has been incompletely investigated. This study investigates short- and intermediate-term outcomes after PVR in ACHD. Using State Inpatient Databases from the Healthcare Cost and Utilization Project, we investigated both hospitalization rate and financial burden accrued over the 12-month period after PVR compared with the 12 months before. Among 202 patients who underwent PVR, per patient-year hospitalization rates doubled in the year after PVR compared with the year before (0...
August 22, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27620913/nt-probnp-and-exercise-capacity-in-adult-patients-with-congenital-heart-disease-and-a%C3%A2-prosthetic-valve-a%C3%A2-multicentre-prostava-study
#15
R C Schoonbeek, P G Pieper, Y J van Slooten, H G Freling, G T Sieswerda, A P J van Dijk, M R M Jongbloed, M C Post, B J Bouma, R M F Berger, T Ebels, J P van Melle
OBJECTIVES: N-terminal B‑type natriuretic peptide (NT-proBNP) is an important biomarker for the detection of heart failure. Adults with congenital heart disease (ACHD) and a prosthetic heart valve are at risk for heart failure. This study aimed to determine the value of NT-proBNP in ACHD patients with a prosthetic valve and investigate its relationship with cardiac function and exercise capacity. METHODS: In this multi-centre cross-sectional observational study, data regarding medical history, echocardiography, exercise testing (VO2peak) and laboratory blood evaluation (including NT-proBNP) were collected in ACHD patients with a single prosthetic valve (either homografts, heterografts or mechanical valves)...
November 2016: Netherlands Heart Journal
https://www.readbyqxmd.com/read/27561764/wait-list-outcomes-for-adults-with-congenital-heart-disease-listed-for-heart%C3%A2-transplantation-in-the-u-s
#16
Laith I Alshawabkeh, Nan Hu, Knute D Carter, Alexander R Opotowsky, KellyAnn Light-McGroary, Joseph E Cavanaugh, Heather L Bartlett
BACKGROUND: Heart failure represents a common end-stage syndrome for many adults with congenital heart disease (ACHD). These patients, however, have been excluded from most heart transplantation research. It is not known how current criteria, derived from non-ACHD populations, used to determine priority at the time of transplant listing, impact the outcomes for ACHD patients listed for heart transplantation. OBJECTIVES: The goal of this study was to investigate outcomes of ACHD in comparison to non-ACHD patients while listed for heart transplantation...
August 30, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27485737/burden-of-heart-failure-in-adults-with-congenital-heart-disease
#17
Laith I Alshawabkeh, Alexander R Opotowsky
Patients born with congenital heart disease (CHD) have benefited from remarkable advances in surgical and catheter-based interventions. As a result, the majority of children born with even the most complex forms of CHD live into adulthood. The specialized field of adult CHD (ACHD) was born out of the necessity to care for this new population of survivors of childhood CHD and their distinctive features. In this review, relevant aspects of ACHD that lead to, and are affected by, heart failure will be examined along with the increasing prevalence of HF in the burgeoning population of ACHD...
October 2016: Current Heart Failure Reports
https://www.readbyqxmd.com/read/27476099/health-care-costs-for-adults-with-congenital-heart-disease-in-the-united-states-2002-to-2012
#18
David A Briston, Elisa A Bradley, Aarthi Sabanayagam, Ali N Zaidi
More adults than children with congenital heart disease (CHD) are alive today. Few studies have evaluated adult congenital heart disease (ACHD) health care utilization in the United States. Data from the National Inpatient Sample from 2002 to 2012, using International Classification of Diseases, Ninth Revision, codes for moderate and complex CHD were analyzed. Hospital discharges, total billed and reimbursed amounts, length of stay, and gender/age disparities were evaluated. There was an increase in CHD discharges (moderate CHD: 4,742 vs 6,545; severe CHD: 807 vs 1,115) and total billed and reimbursed dollar amounts across all CHD (billed: $2...
August 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27436116/postcardiotomy-ecmo-support-after-high-risk-operations-in-adult-congenital-heart-disease
#19
Benjamin Acheampong, Jonathan N Johnson, John M Stulak, Joseph A Dearani, Sudhir S Kushwaha, Richard C Daly, Dawit T Haile, Gregory J Schears
BACKGROUND: Cardiac operations in high-risk adult congenital heart disease (ACHD) patients may require mechanical circulatory support (MCS), such as extracorporeal membrane oxygenation (ECMO) or intraaortic balloon pump (IABP), to allow the cardiopulmonary system to recover. METHODS: We reviewed records for all ACHD patients who required MCS following cardiotomy at our institution from 1/2001 to 12/2013. RESULTS: During the study period, 2264 (mean age 39...
December 2016: Congenital Heart Disease
https://www.readbyqxmd.com/read/27435587/use-of-dofetilide-in-adult-patients-with-atrial-arrhythmias-and-congenital-heart-disease-a-paces-collaborative-study
#20
Iqbal El-Assaad, Sadeer G Al-Kindi, JoEllyn Abraham, Shubhayan Sanatani, David J Bradley, Colby Halsey, Ian H Law, Seshadri Balaji, Ira Shetty, Peter F Aziz
BACKGROUND: Arrhythmia management has become the major treatment challenge in adult patients with congenital heart disease (ACHD). OBJECTIVE: We sought to investigate the utility and safety profile of dofetilide for atrial arrhythmias in ACHD. METHODS: A retrospective chart review was performed. We included patients (age ≥18 years) with congenital heart disease who had atrial fibrillation (AF) or intra-atrial reentrant tachycardia treated with dofetilide...
October 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
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