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Sérgio Monteiro de Almeida, Sônia Mara Raboni, Meri Bordignon Nogueira, Luine R Renaud Vidal
The presence of hemoglobin in samples are considered an important inhibitory factor for polymerase chain reaction (PCR). The aim of this study was to examine the influence of red blood cells (RBC)s in cerebrospinal fluid (CSF) as an inhibitory factor to reverse transcription polymerase chain reaction (RT-PCR) for enteroviruses (EV). Forty-four CSF samples from patients showing characteristics of viral meningitis were assessed for EV by RT-PCR. Viral RNA extracted with guanidine isothyocianate buffer and virus detection was performed by in-house nested PCR...
October 2016: Arquivos de Neuro-psiquiatria
Sanna L Lahtinen, Janne H Liisanantti, Meri M Poukkanen, Päivi A Laurila
BACKGROUND: Goal-directed fluid management using stroke volume variation (SVV) analysis is not well studied in free flap reconstruction surgery in patients with head and neck cancer. METHODS: Patients operated due to cancer of the head and neck with free flap reconstruction during 2008-2010 and 2012-2014 in Oulu University Hospital were retrospectively evaluated to determine the impact of SVV-guided fluid management on perioperative fluid balance, postoperative complications and hospital length of stay (LOS)...
October 19, 2016: Minerva Anestesiologica
Carlos M Mery, Keila N Lopez, Silvana Molossi, S Kristen Sexson-Tejtel, Rajesh Krishnamurthy, E Dean McKenzie, Charles D Fraser, Scott B Cantor
OBJECTIVES: The goal of this study was to use decision analysis to evaluate the impact of varying uncertainties on the outcomes of patients with anomalous aortic origin of a coronary artery. METHODS: Two separate decision analysis models were created: one for anomalous left coronary artery (ALCA) and one for anomalous right coronary artery (ARCA). Three strategies were compared: observation, exercise restriction, and surgery. Probabilities and health utilities were estimated on the basis of existing literature...
November 2016: Journal of Thoracic and Cardiovascular Surgery
Virginie Cailleau, Bérangère Thirioux, Bernard Méry, Jean-Louis Senon, Nematollah Jaafari
The review of literature devoted to empathy deficits of sexual offenders shows that they have difficulties in identifying specific emotions in specific situations. Their perspective taking abilities range from weak to normal. Face to their victims suffering, their emotional replication would be inhibited. Affective and cognitive impairments in sexual offenders do not result from a general empathy deficit but would however result from the context, cognitive distortions or indifference towards victims. Some sexual offenders are able to decenter from themselves and understand their victims' mental states, but maintain their viewpoint, leading them to not identify with their victims or share their feelings...
October 10, 2016: La Presse Médicale
Eline Lima Borges, José Ferreira Pires, Mery Natali Silva Abreu, Vera Lúcia de Araújo Lima, Patrícia Aparecida Barbosa Silva, Sônia Maria Soares
Objective: to estimate the healing rate of complex surgical wounds and its associated factors. Method: retrospective cohort study from 2003 to 2014 with 160 outpatients of a Brazilian university hospital. Data were obtained through consultation of the medical records. Survival function was estimated using the Kaplan-Meier method and Cox regression model to estimate the likelihood of the occurrence of healing. Results: the complex surgical wound healing rate was 67...
October 10, 2016: Revista Latino-americana de Enfermagem
Wei Phin Tan, Carol Lin, Meri Chen, Leslie A Deane
No abstract text is available yet for this article.
October 7, 2016: Urology
Meena Nathan, Marshall L Jacobs, J William Gaynor, Jane W Newburger, Carolyn Dunbar Masterson, Linda M Lambert, Danielle Hollenbeck-Pringle, Felicia L Trachtenberg, Owen White, Brett R Anderson, Margaret C Bell, Phillip T Burch, Eric M Graham, Jonathan R Kaltman, Kirk R Kanter, Carlos M Mery, Christian Pizarro, Marcus S Schamberger, Michael D Taylor, Jeffrey P Jacobs, Sara K Pasquali
BACKGROUND: Data routinely captured in clinical registries may be leveraged to enhance efficiency of prospective research. The quality of registry data for this purpose has not been studied, however. We evaluated the completeness and accuracy of perioperative data within congenital heart centers' local surgical registries. METHODS: Within 12 Pediatric Heart Network (PHN) sites, we evaluated 31 perioperative variables (and their subcategories, totaling 113 unique fields) collected via sites' local clinical registries for submission to The Society of Thoracic Surgeons Database, compared with chart review by PHN research coordinators...
October 7, 2016: Annals of Thoracic Surgery
Brian Finan, Christoffer Clemmensen, Zhimeng Zhu, Kerstin Stemmer, Karine Gauthier, Luisa Müller, Meri De Angelis, Kristin Moreth, Frauke Neff, Diego Perez-Tilve, Katrin Fischer, Dominik Lutter, Miguel A Sánchez-Garrido, Peng Liu, Jan Tuckermann, Mohsen Malehmir, Marc E Healy, Achim Weber, Mathias Heikenwalder, Martin Jastroch, Maximilian Kleinert, Sigrid Jall, Sara Brandt, Frédéric Flamant, Karl-Werner Schramm, Heike Biebermann, Yvonne Döring, Christian Weber, Kirk M Habegger, Michaela Keuper, Vasily Gelfanov, Fa Liu, Josef Köhrle, Jan Rozman, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Susanna M Hofmann, Bin Yang, Matthias H Tschöp, Richard DiMarchi, Timo D Müller
Glucagon and thyroid hormone (T3) exhibit therapeutic potential for metabolic disease but also exhibit undesired effects. We achieved synergistic effects of these two hormones and mitigation of their adverse effects by engineering chemical conjugates enabling delivery of both activities within one precisely targeted molecule. Coordinated glucagon and T3 actions synergize to correct hyperlipidemia, steatohepatitis, atherosclerosis, glucose intolerance, and obesity in metabolically compromised mice. We demonstrate that each hormonal constituent mutually enriches cellular processes in hepatocytes and adipocytes via enhanced hepatic cholesterol metabolism and white fat browning...
October 5, 2016: Cell
Carlos M Mery, R Michael Nieto, Luis E De León, Shaine A Morris, Wei Zhang, John L Colquitt, Iki Adachi, Lauren C Kane, Jeffrey S Heinle, E Dean McKenzie, Charles D Fraser
BACKGROUND: Predictors for single ventricle palliation (SVP) or successful biventricular repair (BVR) in patients with borderline left-side heart structures are not well defined. The goal was to evaluate the role of echocardiography and intracardiac exploration in determining feasibility of BVR. METHODS: All neonates surgically treated from 1995 to 2015 with mitral valve (MV), aortic valve, or left ventricle end-diastolic dimension z score of -2 or less for whom management was controversial were included...
October 4, 2016: Annals of Thoracic Surgery
Siyi Wanggou, Chengyuan Feng, Yuanyang Xie, Linrong Ye, Feiyifan Wang, Xuejun Li
Background: Glioblastoma is the most lethal primary brain tumor in adults. Aberrant signal transduction pathways, associated with the progression of glioblastoma, have been identified recently and may offer a potential gene therapy strategy. Methods and Findings: We first used the sample level enrichment analysis to transfer gene expression profile of TCGA dataset into pathway enrichment z-score matrix. Then, we classified glioblastoma into five subtypes (Cluster A to Cluster E) by the consensus clustering and silhouette analysis...
2016: Journal of Cancer
Peter Hilpert, Ashley K Randall, Piotr Sorokowski, David C Atkins, Agnieszka Sorokowska, Khodabakhsh Ahmadi, Ahmad M Alghraibeh, Richmond Aryeetey, Anna Bertoni, Karim Bettache, Marta Błażejewska, Guy Bodenmann, Jessica Borders, Tiago S Bortolini, Marina Butovskaya, Felipe N Castro, Hakan Cetinkaya, Diana Cunha, Oana A David, Anita DeLongis, Fahd A Dileym, Alejandra D C Domínguez Espinosa, Silvia Donato, Daria Dronova, Seda Dural, Maryanne Fisher, Tomasz Frackowiak, Evrim Gulbetekin, Aslıhan Hamamcıoğlu Akkaya, Karolina Hansen, Wallisen T Hattori, Ivana Hromatko, Raffaella Iafrate, Bawo O James, Feng Jiang, Charles O Kimamo, David B King, Fırat Koç, Amos Laar, Fívia De Araújo Lopes, Rocio Martinez, Norbert Mesko, Natalya Molodovskaya, Khadijeh Moradi, Zahrasadat Motahari, Jean C Natividade, Joseph Ntayi, Oluyinka Ojedokun, Mohd S B Omar-Fauzee, Ike E Onyishi, Barış Özener, Anna Paluszak, Alda Portugal, Ana P Relvas, Muhammad Rizwan, Svjetlana Salkičević, Ivan Sarmány-Schuller, Eftychia Stamkou, Stanislava Stoyanova, Denisa Šukolová, Nina Sutresna, Meri Tadinac, Andero Teras, Edna L Tinoco Ponciano, Ritu Tripathi, Nachiketa Tripathi, Mamta Tripathi, Noa Vilchinsky, Feng Xu, Maria E Yamamoto, Gyesook Yoo
[This corrects the article on p. 1106 in vol. 7, PMID: 27551269.].
2016: Frontiers in Psychology
Kristian M Forbes, Tapio Mappes, Tarja Sironen, Tomas Strandin, Peter Stuart, Seppo Meri, Olli Vapalahti, Heikki Henttonen, Otso Huitu
Trade-offs in the allocation of finite-energy resources among immunological defences and other physiological processes are believed to influence infection risk and disease severity in food-limited wildlife populations. However, this prediction has received little experimental investigation. Here we test the hypothesis that food limitation impairs the ability of wild field voles (Microtus agrestis) to mount an immune response against parasite infections. We conducted a replicated experiment on vole populations maintained in large outdoor enclosures during boreal winter, using food supplementation and anthelmintic treatment of intestinal nematodes...
September 2016: Biology Letters
J B Guy, B Méry, C Rancoule, A Vallard, S Espenel, A S Wozny, S Simonet, D Bernard, D Ardail, M Beuve, G Alphonse, C Rodriguez-Lafrasse, N Magné
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
Anna Rozman, David Turk, Mery Elashvili, Carolin Dohle
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
Carlos M Mery
No abstract text is available yet for this article.
September 3, 2016: Journal of Thoracic and Cardiovascular Surgery
Meri De Angelis, Florian Giesert, Brian Finan, Christoffer Clemmensen, Timo D Müller, Daniela Vogt-Weisenhorn, Matthias H Tschöp, Karl-Werner Schramm
Thyroid hormones (THs) play a critical role in the regulation of many biological processes such as growth, metabolism and development both in humans and wildlife. In general, TH levels are measured by immunoassay (IA) methods but the specificity of the antibodies used in these assays limits selectivity. In the last decade, several analytical methods using liquid chromatography-mass spectrometry (LC-MS) and tandem mass spectrometry (LC-MS/MS) have been developed to measure THs. These new techniques proved to be more accurate than the IA analysis and they were widely used for the determination of TH level in different human and animal tissues...
October 15, 2016: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
Sharmila Chatterjee, Amit Chattopadhyay, Surendra Nath Senapati, Dipti Rani Samanta, Leslie Elliott, Dana Loomis, Lesly Mery, Pinaki Panigrahi
Cancer registration, an important component of cancer surveillance, is essential to a uni ed, scienti c and public health approach to cancer prevention and control. India has one of the highest cancer incidence and mortality rates in the world. A good surveillance system in the form of cancer registries is important for planning and evaluating cancer-control activities. Cancer registration in India was initiated in 1964 and expanded since 1982, through initiation of the National Cancer Registry Program (NCRP) by the Indian Council of Medical Research...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
Alexandre Mery, Boualem Sendid, Nadine François, Marjorie Cornu, Julien Poissy, Yann Guerardel, Daniel Poulain
BACKGROUND: We recently developed a mass spectrometry (MS) procedure based on the detection of a serum disaccharide (MS-DS) in patients with invasive candidiasis (IC). Here, we compare the performance of MS-DS for the diagnosis of IC, invasive aspergillosis (IA) and mucormycosis (MM) with commercially available antigen detection tests. METHODS: This retrospective study included 48 patients (23 IC/74 sera, 15 IA/40 sera and 10 MM/15 sera) and 49 appropriate controls (102 sera)...
September 7, 2016: Journal of Clinical Microbiology
Wei Phin Tan, Carol Lin, Meri Chen, Leslie A Deane
OBJECTIVE: To evaluate whether periprostatic fat volume and periprostatic fat ratio as determined by multiparametric magnetic resonance imaging (mpMRI) correlate with the presence of high-grade prostate cancer. MATERIALS AND METHODS: A total of 295 consecutive patients (median age: 64, range: 38-84) underwent mpMRI of the prostate gland between August 2013 and February 2015. All patients underwent a 3 Tesla mpMRI. Using DynaCAD (Invivo, Gainesville, FL), we calculated the prostate volume and volume of the periprostatic fat seen on mpMRI...
September 1, 2016: Urology
David Horne, Jolie J Britt, Wanda C Miller-Hance, Shailendra Das, Carlos M Mery
No abstract text is available yet for this article.
September 2016: World Journal for Pediatric & Congenital Heart Surgery
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