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https://www.readbyqxmd.com/read/29230597/presence-of-post-systolic-shortening-is-an-independent-predictor-of-heart-failure-in-patients-following-st-segment-elevation-myocardial-infarction
#1
Philip Brainin, Sune Haahr-Pedersen, Morten Sengeløv, Flemming Javier Olsen, Thomas Fritz-Hansen, Jan Skov Jensen, Tor Biering-Sørensen
Following an ischemic event post systolic shortening (PSS) may occur. We investigated the association between PSS in patients with ST-segment elevation myocardial infarction (STEMI) following primary percutaneous coronary intervention (pPCI) and occurrence of cardiovascular events at follow-up. A total of 373 patients admitted with STEMI and treated with pPCI were prospectively included in the study cohort. All patients were examined by echocardiography a median of 2 days after admission (interquartile range, 1-3 days)...
December 11, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29226357/atrial-deformation-correlated-with-functional-capacity-in-mitral-stenosis-patients
#2
Chen-Yu Chien, Chih-Wei Chen, Tin-Kwang Lin, Yu Lin, Jnnu-Wen Lin, Yi-Da Li, Chi-Hsien Chen, Wei-Chuan Tsai
BACKGROUND: Left atrial (LA) dysfunction, expressed as impaired LA deformation using two-dimensional (2D) strain imaging, has been observed in association with rheumatic mitral stenosis (MS). However, the clinical role of speckle tracking echocardiography (STE)-derived LA strain has rarely been studied in MS. AIM: This study aimed to identify the determinants of New York Heart Association (NYHA) functional class in patients with mitral stenosis and to investigate the relationship between left atrial deformation as measured by two-dimensional STE-derived LA strain and heart failure symptoms...
December 11, 2017: Echocardiography
https://www.readbyqxmd.com/read/29216794/fragmented-qrs-complexes-are-associated-with-left-ventricular-dysfunction-in-patients-with-type-2-diabetes-mellitus-a-two-dimensional-speckle-tracking-echocardiography-study
#3
Adil Bayramoğlu, Hakan Taşolar, Yasemin Kaya, Osman Bektaş, Ahmet Kaya, Mehmet Yaman, Zeki Yüksel Günaydın
BACKGROUND: Heart failure may develop independently of coronary artery disease in diabetes mellitus (DM) patients. Fragmented QRS (fQRS) is a marker of myocardial fibrosis or scar tissue and is related to an increase in cardiovascular adverse events. In this study, we examined the utility of speckle tracking echocardiography (STE) in assessing LV function in DM patients with fQRS. METHODS AND RESULTS: The current study included 178 consecutive patients diagnosed with type-2 DM...
December 7, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/29196096/effects-of-isolated-tobacco-alkaloids-and-tobacco-products-on-deprivation-induced-food-intake-and-meal-patterns-in-rats
#4
Patricia E Bunney, Mylissa Hansen, Mark LeSage
The ability of smoking to reduce body weight serves as motivation for continued smoking. It is unclear to what extent non-nicotine constituents in cigarettes are contributing to the weight-reducing effect of smoking. The purpose of the current study was to examine the effects of nicotine and four minor tobacco alkaloids (nornicotine, cotinine, anatabine, and anabasine) on food intake, one of the key regulators of body weight. In addition, a smokeless tobacco extract (STE) and e-cigarette (EC) refill liquid were used to model the effects of actual tobacco product exposure on food intake...
November 28, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/29195659/validation-of-cardiac-magnetic-resonance-tissue-tracking-in-the-rapid-assessment-of-rv-function-a%C3%A2-comparative-study-to-echocardiography
#5
X Tong, J Poon, A Li, C Kit, A Yamada, K Shiino, L F Ling, Y H Choe, J Chan, Y-K Lau, M-Y Ng
AIM: To investigate the accuracy of cardiac magnetic resonance (CMR) tissue tracking (CMR-TT) and speckle tracking echocardiography (STE) against CMR determined right ventricular (RV) ejection fraction (RVEF) and to identify an optimal cut-off value for STE and CMR-TT to determine RVEF <45% and compare this to other conventional methods for estimating RVEF in dilated cardiomyopathy (DCM) patients. MATERIALS AND METHODS: Twenty-nine DCM patients were recruited prospectively...
November 28, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29191713/assessment-of-right-atrial-function-with-speckle-tracking-echocardiography-after-percutaneous-closure-of-an-atrial-septal-defect
#6
Onder Ozturk, Unal Ozturk, Sengul Ozturk
INTRODUCTION: Speckle tracking echocardiography (STE) for two-dimensional (2D) strain analysis is a new tool to assess myocardial function. The aim of this study was to assess right atrial (RA) function using STE in patients with an atrial septal defect (ASD) before and one month after percutaneous closure. METHODS: We prospectively examined 32 consecutive patients (nine male, 23 female) who underwent percutaneous transcatheter closure of a secundum ASD between June 2013 and December 2015...
November 27, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29188318/myocardial-strain-using-cardiac-mr-feature-tracking-and-speckle-tracking-echocardiography-in-duchenne-muscular-dystrophy-patients
#7
Bryan Siegel, Laura Olivieri, Heather Gordish-Dressman, Christopher F Spurney
Duchenne muscular dystrophy (DMD) is an inherited X-linked disorder with an incidence of 1 in 3500 male births, and cardiomyopathy is becoming the leading cause of death. While Cardiac MRI (CMR) and late gadolinium enhancement (LGE) are important tools in recognizing myocardial involvement, myocardial strain imaging may demonstrate early changes and allow patients to avoid gadolinium contrast. We performed CMR feature tracking (FT) and echo-based speckle tracking (STE) strain measures on DMD patients and age/sex matched controls who had received a CMR with contrast and transthoracic echocardiogram...
November 29, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29178486/developing-and-characterizing-mr-ct-visible-materials-used-in-qa-phantoms-for-mrgrt-systems
#8
Angela Steinmann, R Jason Stafford, Gabriel Sawakuchi, Zhifei Wen, Laurence Court, Clifton D Fuller, David Followill
PURPOSE: Synthetic tissue equivalent (STE) materials currently used to simulate tumor and surrounding tissues for IROC-Houston's anthropomorphic head and thorax QA phantoms cannot be visualized using magnetic resonance (MR) imaging. The purpose of this study was to characterize dual MR/CT visible STE materials that can be used in an end-to-end QA phantom for MR guided radiotherapy (MRgRT) modalities. METHODS: Over 80 materials' MR, CT, and dosimetric STE properties were investigated for use in MRgRT QA phantoms...
November 27, 2017: Medical Physics
https://www.readbyqxmd.com/read/29174985/role-of-p-glycoprotein-in-deoxynivalenol-mediated-in-vitro-toxicity
#9
Lada Ivanova, Christiane Kruse Fæste, Anita Solhaug
Deoxynivalenol (DON) is the most prevalent mycotoxin produced by grain-infecting Fusarium strains and frequently occurs in small cereals all over the world. After ingestion, DON is absorbed in the gut, which leads dose-dependently to critical health effects. In the present study, we have further investigated DON's previously reported affinity to the efflux transporter P-glycoprotein (Pgp) in the apical enterocyte membrane. Interaction with Pgp was studied in human colorectal adenocarcinoma (Caco-2) cells and Madin-Darby Canine Kidney wild-type (MDCKII-wt) and Pgp-overexpressing (MDCKII-MDR1) cells in different transport and cytotoxicity experiments...
November 23, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/29174339/feasibility-of-left-ventricular-global-longitudinal-strain-measurements-from-contrast-enhanced-echocardiographic-images
#10
Diego Medvedofsky, Roberto M Lang, Eric Kruse, Brittney Guile, Lynn Weinert, Boguslawa Ciszek, Zachary Jacobson, Jacqueline Negron, Valentina Volpato, Aldo Prado, Amit R Patel, Victor Mor-Avi
BACKGROUND: Although left ventricular global longitudinal strain (GLS) is an index of systolic function recommended by the guidelines, poor image quality may hamper strain measurements. While contrast agents are commonly used to improve endocardial visualization, no commercial speckle-tracking software is able to measure strain in contrast-enhanced images. This study aimed to test the accuracy of speckle-tracking software when applied to contrast-enhanced images in patients with suboptimal image quality...
November 23, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29174244/left-ventricular-global-longitudinal-strain-following-revascularization-in-acute-st-elevation-myocardial-infarction-a-comparison-of-primary-angioplasty-and-streptokinase-based-pharmacoinvasive-strategy
#11
Amal Paul, Paul V George
OBJECTIVE: Tenecteplase-based pharmacoinvasive percutaneous coronary intervention (PCI) has been shown to yield outcomes comparable to primary PCI in the setting of acute ST elevation myocardial infarction (STEMI). This study was designed to compare the efficacy of pharmacoinvasive PCI following successful thrombolysis with Streptokinase versus primary PCI in patients with STEMI. METHODOLOGY: We conducted a prospective single center observational study in 120 patients with STEMI who underwent primary PCI (n=60) and Streptokinase-based pharmacoinvasive PCI (n=60)...
November 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/29168054/cardiac-function-in-patients-with-polymyositis-or-dermatomyositis-a-three-dimensional-speckle-tracking-echocardiography-study
#12
Yue Zhong, Wenjuan Bai, Qibing Xie, Jianhong Sun, Hong Tang, Li Rao
Cardiac event is a major cause of death in patients with idiopathic inflammatory myopathies (IIM). The most frequent IIMs are polymyositis (PM) and dermatomyositis (DM). The purpose of this study was to analyze cardiac involvement by three-dimensional speckle-tracking echocardiography (3D STE) in patients with PM or DM, and to identify the relationship of cardiac injury with clinical characteristics and disease-specific parameters. 60 PM/DM patients with preserved left ventricular ejection fraction and 30 matched healthy controls were assessed by conventional echocardiography, 3D STE with biventricular strain analysis and electrocardiogram...
November 22, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29167183/evolution-of-subclinical-myocardial-dysfunction-detected-by-two-dimensional-and-three-dimensional-speckle-tracking-in-asymptomatic-type-1-diabetic-patients-a-long%C3%A2-term-follow-up-study
#13
Anne Ringle, Anne Dornhorst, Michaela B Rehman, Cristina Ruisanchez, Petros Nihoyannopoulos
BACKGROUND: We sought to assess the long-term evolution of left ventricular (LV) function using two-dimensional (2D) and three-dimensional (3D) speckle tracking echocardiography (STE) for the detection of preclinical diabetic cardiomyopathy, in asymptomatic type 1 diabetic patients, over a 6-year follow-up. DESIGN AND METHODS: Sixty-six asymptomatic type 1 diabetic patients with no cardiovascular risk factors were compared to 26 matched healthy controls. Conventional, 2D and 3D-STE were performed at baseline...
December 2017: Echo Research and Practice
https://www.readbyqxmd.com/read/29164624/suppression-of-uvb-mediated-matrix-metalloproteinase-generation-by-sorbus-commixta-twig-extract-in-human-dermal-fibroblasts
#14
Song Hua Xuan, Young Min Park, So Hyun Park, Hyo Jin Jeong, Soo Nam Park
Sorbus commixta is a traditional oriental medicinal plant that grows in East Asian countries such as Korea, Japan, and China. The twig of S. commixta has been considered valuable for centuries to treat diseases including asthma, cough, and other bronchial disorders. However, the effect of S. commixta twig extract on human skin has not been investigated well. The present study aimed at assessing the anti-photoaging effect of S. commixta twig ethanol extract (STE) on ultraviolet B (UVB)-induced matrix metalloproteinase (MMP) levels and its underlying mechanism in human dermal fibroblasts...
November 22, 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/29151290/-early-detection-of-the-cardiotoxicity-induced-by-chemotherapy-drug-through-two-dimensional-speckle-tracking-echocardiography-combined-with-high-sensitive-cardiac-troponin-t
#15
W Wang, Y Kang, X H Shu, X D Shen, B He
Objective: To investigate the clinical value of two-dimensional speckle tracking echocardiography(2D-STE) combined with high-sensitive cardiac troponin T (hs-cTnT) in early detection of the cardiotoxicity induced by chemotherapy drug. Methods: Seventy-five non-Hodgkin's lymphoma patients who received the CHOP regimen were recruited in this study. Conventional echocardiography and 2D-STE were performed on these patients before chemotherapy, the second day after the third course of chemotherapy (during chemotherapy) and the second day after the last course of chemotherapy (after chemotherapy)...
November 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/29150155/the-association-of-functional-capacity-with-right-atrial-deformation-in-patients-with-pulmonary-arterial-hypertension-a-study-with-two-dimensional-speckle-tracking
#16
Weiwei Liu, Yueheng Wang, Jinling Zhou, Hui Bai, Feng Wang, Ju Wang
BACKGROUND: The purpose of this study was to assess right atrial (RA) myocardial mechanics in pulmonary hypertension (PH) patients using two-dimensional speckle tracking (2D-STE), and define the relationship between RA function and exercise capacity in PH patients. METHODS: Thirty-eight consecutive PH patients were studied and compared with a control group of 25 healthy volunteers. Peak atrial longitudinal strain (PALS), RA strain rate were measured in all subjects...
April 13, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29146487/mitochondria-a-master-regulator-in-macrophage-and-t-cell-immunity
#17
REVIEW
Pu-Ste Liu, Ping-Chih Ho
Orchestrating biological activities of immune cells through metabolic reprogramming reveals a new approach to harnessing immune responses. Increasing evidence reveals that the mitochondrion is a central regulator for modulating metabolic reprogramming and controlling immune cell activation and functions. In addition to supporting bioenergetic demands, the mitochondrion serves as a signaling platform through the generation of reactive oxygen species and metabolites of the tricarboxylic acid cycle to modulate signaling cascades controlling immune cell activation and immune responses...
November 13, 2017: Mitochondrion
https://www.readbyqxmd.com/read/29133200/histologic-and-hemodynamic-correlates-of-right-ventricular-function-in-a-pressure-overload-model-a-study-using-three-dimensional-speckle-tracking-echocardiography
#18
Yuman Li, Lei Li, Junwei Liu, Mengmei Li, Qing Lv, Jing Wang, Lin He, Mingxing Xie
The aim of our study was to assess the characterization of right ventricular (RV) deformation using three-dimensional (3D) speckle tracking echocardiography (STE) and association of 3D-STE indices with histologic and hemodynamic parameters in a chronic RV pressure overload animal model. Pulmonary artery banding (PAB) was used to induce RV pressure overload in seven beagles. 3D-STE, histologic and hemodynamic measurements were performed in PAB and sham-operated beagles 3 mo after PAB. RV longitudinal, radial and circumferential strain was measured from 3D-STE...
November 10, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29131285/favourable-hypotensive-effect-after-standardised-tomato-extract-treatment-in-hypertensive-subjects-at-high-estimated-cardiovascular-risk-a-randomised-controlled-trial
#19
Beata Krasińska, Angelika Osińska, Aleksandra Krasińska, Maciej Osiński, Piotr Rzymski, Andrzej Tykarski, Zbigniew Krasiński
BACKGROUND: Cardiovascular (CV) diseases remain a leading global cause of death. Lowering blood pressure (BP) reduces the risk of CV complications, especially stroke and acute coronary events, and it delays the progression of kidney disease. Adequate non-pharmacological treatment improves the effectiveness of the antihypertensive therapy. A Mediterranean diet with high content of vegetables (rich in tomatoes) is associated with a reduced CV risk. AIM: The main objective of the present study was to assess if the addition of standardised extract of tomato (STE) or acetylsalicylic acid (ASA) to standard antihypertensive therapy can improve blood pressure control in patients with hypertension (HT)...
November 13, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/29130575/a-prospective-investigation-to-evaluate-risk-factors-for-lower-extremity-injury-risk-in-male-youth-soccer-players
#20
Paul J Read, Jon L Oliver, Mark B A De Ste Croix, Gregory D Myer, Rhodri S Lloyd
There is an inherent risk of injury in male youth football; however, pertinent risk factors for injury have yet to be examined. This study used a prospective cohort design with 357 elite male youth football players (aged 10-18 years) assessed during the pre-season period and then monitored during the season recording all non-contact lower extremity injuries. Screening tests included: single leg hop for distance (SLHD); 75% of maximum hop and stick (75%Hop); single leg countermovement jump (SLCMJ); and the tuck jump assessment (TJ)...
November 11, 2017: Scandinavian Journal of Medicine & Science in Sports
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