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https://www.readbyqxmd.com/read/28431123/surgical-intervention-for-ground-glass-dominant-lesions-observation-or-outright-resection
#1
Mariko Fukui, Kenji Suzuki, Takeshi Matsunaga, Shiaki Oh, Kazuya Takamochi
Background: The management of ground glass opacity (GGO) on computed tomography (CT) remains controversial. Information of the relationship between clinical behavior and pathological invasiveness of GGO is valuable for management. We conducted this retrospective study to establish differences in the pathological invasiveness between GGO with and without changes. Methods: Among 1762 patients, the following criteria was used: (1) maximum tumor diameter of 3 cm or less, (2) tumor having 50% or more GGO and (3) resection after at least three months of follow up...
April 18, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28419326/accessibility-to-surgical-robot-technology-and-prostate-cancer-patient-behavior-for-prostatectomy
#2
Toru Sugihara, Hideo Yasunaga, Hiroki Matsui, Go Nagao, Akira Ishikawa, Tetsuya Fujimura, Hiroshi Fukuhara, Kiyohide Fushimi, Makoto Ohori, Yukio Homma
Background: To examine how surgical robot emergence affects prostate-cancer patient behavior in seeking radical prostatectomy focusing on geographical accessibility. Methods: In Japan, robotic surgery was approved in April 2012. Based on data in the Japanese Diagnosis Procedure Combination database between April 2012 and March 2014, distance to nearest surgical robot and interval days to radical prostatectomy (divided by mean interval in 2011: % interval days to radical prostatectomy) were calculated for individual radical prostatectomy cases at non-robotic hospitals...
April 13, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28414769/creation-of-an-intramedullary-cavity-by-hemorrhagic-necrosis-removal-24-h-after-spinal-cord-contusion-in-rats-for-eventual-intralesional-implantation-of-restorative-materials
#3
Gabriel Guizar-Sahagun, Angelina Martinez-Cruz, Rebecca E Franco-Bourland, Eduardo Cruz-García, Alvaro Corona-Juarez, Araceli Diaz-Ruiz, Israel Grijalva, Horacio J Reyes-Alva, Ignacio Madrazo
Intramedullary hemorrhagic necrosis occurs early after spinal cord injury at the site of injury and adjacent segments. It is considered harmful because of its potential to aggravate secondary injury, and to interfere with axonal regeneration; it might also lead to an unfavorable environment for intralesional implants. Removal of hemorrhagic necrosis has been attempted before with variable results. The invasive nature of these procedures carries the risk of exacerbating damage to the injured cord. The overall objective for this study was to test several strategies for non-damaging removal of hemorrhagic necrosis and characterize the resulting cavity looking for a space for future intralesional therapeutic implants in rats with acute cord injury...
2017: PloS One
https://www.readbyqxmd.com/read/28412561/metastatic-human-breast-cancer-to-the-spine-produces-mechanical-hyperalgesia-and-gait-deficits-in-rodents
#4
Rachel Sarabia-Estrada, Alejandro Ruiz-Valls, Hugo Guerrero-Cazares, Ana M Ampuero, Ismael Jimenez-Estrada, Samantha De Silva, Lydia J Bernhardt, C Rory Goodwin, A Karim Ahmed, Yuxin Li, Neil A Phillips, Ziya L Gokaslan, Alfredo Quiñones-Hinojosa, Daniel M Sciubba
BACKGROUND CONTEXT: Metastases to the spine are a common source of severe pain in cancer patients. The secondary effects of spinal metastases include pain, bone fractures, hypercalcemia, and neurological deficits. As the disease progresses, pain severity can increase until it becomes refractory to medical treatments and leads to a decreased quality of life for patients. A key obstacle in the study of pain-induced spinal cancer is the lack of reliable and reproducible spine cancer animal models...
April 13, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28412141/toll-like-receptor-4-activation-can-be-either-detrimental-or-beneficial-following-mild-repetitive-traumatic-brain-injury-depending-on-timing-of-activation
#5
Frances Corrigan, Alina Arulsamy, Lyndsey E Collins-Praino, Joshua L Holmes, Robert Vink
A history of repeated concussion has been linked to the later development of neurodegeneration, which is associated with the accumulation of hyperphosphorylated tau and the development of behavioral deficits. However, the role that exogenous factors, such as immune activation, may play in the development of neurodegeneration following repeated mild traumatic brain injury (rmTBI) has not yet been explored. To investigate, male Sprague-Dawley rats were administered three mTBIs 5 days apart using the diffuse impact-acceleration model to generate ∼100G...
April 13, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28411313/roux-en-y-gastric-bypass-and-sleeve-gastrectomy-does-not-affect-food-preferences-when-assessed-by-an-ad-libitum-buffet-meal
#6
Mette S Nielsen, Bodil J Christensen, Christian Ritz, Simone Rasmussen, Thea T Hansen, Wender L P Bredie, Carel W le Roux, Anders Sjödin, Julie B Schmidt
BACKGROUND: Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) lead to a reduction in energy intake. It is uncertain whether this reduction is simply due to eating smaller portions or if surgery changes food preferences towards less energy-dense food. Previous results rely on verbal reports, which may be prone to recall bias and underestimation of especially unhealthy foods. METHODS: Using an ad libitum buffet meal targeting direct behavior, we investigated if RYGB and SG surgery leads to changes in food preferences...
April 14, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28410820/-optimizing-post-operative-pain-management-in-latin-america
#7
João Batista Santos Garcia, Patricia Bonilla, Durval Campos Kraychette, Fernando Cantú Flores, Elizabeth Diaz Perez de Valtolina, Carlos Guerrero
Post-operative pain management is a significant problem in clinical practice in Latin America. Insufficient or inappropriate pain management is in large part due to insufficient knowledge, attitudes and education, and poor communications at various levels. In addition, the lack of awareness of the availability and importance of clear policies and guidelines for recording pain intensity, the use of specific analgesics and the proper approach to patient education have led to the consistent under-treatment of pain management in the region...
April 11, 2017: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/28409135/evaluation-of-serum-levels-of-c-reactive-protein-after-total-knee-arthroplasty
#8
João Maurício Barretto, Fabrício Bolpato Loures, Rodrigo Sattamini Pires E Albuquerque, Filipe das Neves Bezerra, Rafael Vinagre Faro, Naasson Trindade Cavanellas
OBJECTIVE: To evaluate the behavior of C-reactive protein (CRP) levels in the first three weeks after total knee arthroplasty (TKA) and define the factors related to its variation. METHODS: We evaluated the CRP values in 103 patients undergoing primary TKA. Serum CRP was measured on the day before surgery, and on the third and twenty-first days after the procedure. RESULTS: PCR showed sudden increase on the third day after surgery, reaching the mean value of 111...
March 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28403306/quality-of-life-of-patients-who-undergone-myocardial-revascularization-surgery
#9
Hirla Vanessa Soares de Araújo, Thaisa Remigio Figueirêdo, Christefany Régia Braz Costa, Maria Mariana Barros Melo da Silveira, Rebeka Maria de Oliveira Belo, Simone Maria Muniz da Silva Bezerra
OBJECTIVE: to evaluate the quality of life of patients who underwent revascularization surgery. METHOD: a descriptive, cross sectional study, with quantitative approach carried out with 75 patients. The questionnaire WHOQOL-Bref was used to evaluate the quality of life (QOL). RESULTS: patients' QOL evaluation presented a moderate result, with need of improvement of all domains. Low income patients had the worst evaluation of QOL in the domain environment (p=0,021), and the ones from Recife/metropolitan area, in the domain social relationship (p=0,021)...
April 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28401051/surgery-in-pediatric-crohn-s-disease-indications-timing-and-post-operative-management
#10
REVIEW
Seung Kim
Pediatric onset Crohn's disease (CD) tends to have complicated behavior (stricture or penetration) than elderly onset CD at diagnosis. Considering the longer duration of the disease in pediatric patients, the accumulative chance of surgical treatment is higher than in adult onset CD patients. Possible operative indications include perianal CD, intestinal stricture or obstruction, abdominal abscess or fistula, intestinal hemorrhage, neoplastic changes and medically untreatable inflammation. Growth retardation is an operative indication only for pediatric patients...
March 2017: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/28399413/personality-traits-of-children-before-and-after-epilepsy-surgery
#11
Olga Braams, Renske Schappin, Joost Meekes, Peter C van Rijen, Onno van Nieuwenhuizen, Kees P Braun, Aag Jennekens-Schinkel
We studied how children with epilepsy (CWE) who are candidates for epilepsy surgery, perceive themselves with respect to overarching personality traits and whether the traits change after surgery. We explored influences of demographic and illness variables. A total of 23 CWE [mean age at inclusion 12.8 (sd 2.3); 12 girls] participated. Using the Dutch Personality Questionnaire Juniors (DPQ-J), we assessed 20 of the CWE shortly before epilepsy surgery and compared the results to those of 39 age- and gender-matched healthy controls...
April 3, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28396294/chronic-ambulatory-electrocorticography-from-human-speech-cortex
#12
Vikram R Rao, Matthew K Leonard, Jonathan K Kleen, Ben A Lucas, Emily A Mirro, Edward F Chang
Direct intracranial recording of human brain activity is an important approach for deciphering neural mechanisms of cognition. Such recordings, usually made in patients with epilepsy undergoing inpatient monitoring for seizure localization, are limited in duration and depend on patients' tolerance for the challenges associated with recovering from brain surgery. Thus, typical intracranial recordings, similar to most non-invasive approaches in humans, provide snapshots of brain activity in acute, highly constrained settings, limiting opportunities to understand long timescale and natural, real-world phenomena...
April 7, 2017: NeuroImage
https://www.readbyqxmd.com/read/28392713/a-case-report-on-the-treatment-of-complex-chronic-pain-and-opioid-dependence-by-a-multidisciplinary-transitional-pain-service-using-the-act-matrix-and-buprenorphine-naloxone
#13
Aliza Z Weinrib, Lindsay C Burns, Alex Mu, Muhammad Abid Azam, Salima Sj Ladak, Karen McRae, Rita Katznelson, Saam Azargive, Cieran Tran, Joel Katz, Hance Clarke
In an era of growing concern about opioid prescribing, the postsurgical period remains a critical window with the risk of significant opioid dose escalation, particularly in patients with a history of chronic pain and presurgical opioid use. The purpose of this case report is to describe the multidisciplinary care of a complex, postsurgical pain patient by an innovative transitional pain service (TPS). A 59-year-old male with complex chronic pain, as well as escalating long-term opioid use, presented with a bleeding duodenal ulcer requiring emergency surgery...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28375968/curve-modulation-and-apex-migration-using-shilla-growth-guidance-rods-for-early-onset-scoliosis-at-5-year-follow-up
#14
John T Wilkinson, Chad E Songy, David B Bumpass, Francis L McCullough, Richard E McCarthy
BACKGROUND: The Shilla procedure was designed to correct and control early-onset spinal deformity while harnessing a child's remaining spinal growth. It allows for controlled axial skeletal growth within the construct, avoiding the need for frequent surgeries to lengthen implants. We hypothesized that curve characteristics evolve over time after initial apex fusion and placement of the Shilla implants. The purpose of this study was to identify trends in curve evolution after Shilla implantation and understand how these changes influence ultimate outcome...
April 3, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28373797/refractory-lesional-parietal-lobe-epilepsy-clinical-electroencephalographic-and-neurodiagnostic-findings
#15
Oğuzhan Kurşun, Hülya Karataş, Neşe Dericioğlu, Serap Saygi
INTRODUCTION: Specialized centers, in the management and surgical treatment of medically refractory epilepsy, emphasize the importance of differentiating the varieties of localization related epilepsies. There has been considerable recent interest in temporal and frontal lobe epileptic syndromes and less attention has been paid to parietal and occipital lobe epilepsies. METHODS: Here we report the clinical, electroencephalographic and neuroimaging characteristics of 46 patients with medically refractory lesional parietal lobe epilepsy who have been followed up for 1-10 years...
September 2016: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/28369624/the-impact-of-subthalamic-deep-brain-stimulation-on-sleep-wake-behavior-a-prospective-electrophysiological-study-in-50-parkinson-patients
#16
Heide Baumann-Vogel, Lukas L Imbach, Oguzkan Sürücü, Lennart Stieglitz, Daniel Waldvogel, Christian R Baumann, Esther Werth
Study Objectives: This prospective observational study was designed to systematically examine the effect of subthalamic deep brain stimulation (DBS) on subjective and objective sleep-wake parameters in Parkinson patients. Methods: In 50 consecutive Parkinson patients undergoing subthalamic DBS, we assessed motor symptoms, medication, the position of DBS electrodes within the subthalamic nucleus, subjective sleep-wake parameters, two-week actigraphy, video-polysomnography studies and sleep EEG frequency and dynamics analyses before and 6 months after surgery...
March 23, 2017: Sleep
https://www.readbyqxmd.com/read/28365950/nitric-oxide-synthesis-modulation-a-possible-diagnostic-and-therapeutic-target-in-colorectal-cancer
#17
Branko Brankovic, Goran Stanojevic, Ivana Stojanovic, Andrej Veljkovic, Gordana Kocic, Predrag Janosevic, Milica Nestorovic, Dejan Petrovic, Boris Djindjic, Ducica Pavlovic, Zoran Krivokapic
PURPOSE: Considering the contradictory literature data about the role of nitric oxide (NO) in colon carcinogenesis, the purpose of this study was to examine the changes of L-arginine metabolites in colon cancer and surrounding tissue as possible molecular markers of tumor behavior after surgery and the possibility of NO synthesis modulation in new individualized therapeutic strategies. METHODS: The study encompassed 50 patients who underwent surgery for colorectal cancer (CRC)...
January 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28360533/effects-of-decompression-on-behavioral-electrophysiologic-and-histomorphologic-recovery-in-a-chronic-sciatic-nerve-compression-model-of-streptozotocin-induced-diabetic-rats
#18
Ping-Hui Wang, Cheng-Chang Yang, Wei-Ren Su, Po-Ting Wu, Shun-Chien Cheng, I-Ming Jou
PURPOSE: To determine susceptibility to decompression surgery in diabetic and nondiabetic peripheral neuropathy using a chronic compression neuropathy model. MATERIALS AND METHODS: Twenty-four streptozotocin-induced diabetic rats were randomly divided into three groups: group I, chronic compression of the left sciatic nerve for 4 weeks with decompression; group II, similar without decompression; and group III, sham exposing the sciatic nerve only. The other 24 nondiabetic rats were assigned to groups IV-VI, which received compression-decompression, compression, and the sham operation, respectively...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28359937/pilot-study-on-laser-propagation-in-maxillary-and-mandibular-bone-grey-level-image-analysis-for-optical-measurements
#19
Monalisa Jacob Guiselini, Alessandro Melo Deana, Daniela de Fátima Teixeira da Silva, Nelson Hideyoshi Koshoji, Raquel Agnelli Mesquita-Ferrari, Katia Llanos do Vale, Marcelo Betti Mascaro, Simone Aleksandra de Moraes, Sandra Kalil Bussadori, Kristianne Porta Santos Fernandes
BACKGROUND: Bone tissue anatomy, density and porosity vary among subjects in different phases of life and even within areas of a single specimen. The optical characteristics of changes in bone tissue are analyzed based on these properties. Photobiomodulation has been used to improve bone healing after surgery or fractures. Thus, knowledge on light propagation is of considerable importance to the obtainment of successful clinical outcomes. OBJECTIVE: This study determines light penetration and distribution in human maxillary and mandibular bones in three different regions (anterior, middle, and posterior)...
March 27, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28359099/pediatric-obesity-assessment-treatment-and-prevention-an-endocrine-society-clinical-practice-guideline
#20
Dennis M Styne, Silva A Arslanian, Ellen L Connor, Ismaa Sadaf Farooqi, M Hassan Murad, Janet H Silverstein, Jack A Yanovski
Cosponsoring Associations: The European Society of Endocrinology and the Pediatric Endocrine Society. This guideline was funded by the Endocrine Society. Objective: To formulate clinical practice guidelines for the assessment, treatment, and prevention of pediatric obesity. Participants: The participants include an Endocrine Society-appointed Task Force of 6 experts, a methodologist, and a medical writer. Evidence: This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation approach to describe the strength of recommendations and the quality of evidence...
March 1, 2017: Journal of Clinical Endocrinology and Metabolism
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