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exercise training and cardiac disease

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https://www.readbyqxmd.com/read/28919891/moderate-intensity-exercise-affects-gut-microbiome-composition-and-influences-cardiac-function-in-myocardial-infarction-mice
#1
Zuheng Liu, Hai-Yue Liu, Haobin Zhou, Qiong Zhan, Wenyan Lai, Qingchun Zeng, Hao Ren, Dingli Xu
Physical exercise is commonly regarded as protective against cardiovascular disease (CVD). Recent studies have reported that exercise alters the gut microbiota and that modification of the gut microbiota can influence cardiac function. Here, we focused on the relationships among exercise, the gut microbiota and cardiac function after myocardial infarction (MI). Four-week-old C57BL/6J mice were exercised on a treadmill for 4 weeks before undergoing left coronary artery ligation. Cardiac function was assessed using echocardiography...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28904878/the-effects-of-different-physical-activities-on-atrial-fibrillation-in-patients-with-hypertension-and-chronic-kidney-disease
#2
Márcio Galindo Kiuchi, Shaojie Chen, Neil Alexander Hoye
BACKGROUND: Atrial fibrillation (AF) is highly common, and is most frequently observed in individuals with hypertension and structural cardiac disease. Sympathetic hyperactivity plays a fundamental role in the progression, maintenance and aggravation of arrhythmia. Endurance exercise training clearly lowers sympathetic activity in sympathoexcitatory disease states, and is well-tolerated by patients with chronic kidney disease (CKD). METHODS: We assessed 50 CKD patients with hypertension...
September 2017: Kidney Research and Clinical Practice
https://www.readbyqxmd.com/read/28903763/troponin-as-ischemic-biomarker-is-related-with-all-three-echocardiographic-risk-factors-for-sudden-death-in-hypertrophic-cardiomyopathy-esc-guidelines-2014
#3
Rafał Hładij, Renata Rajtar-Salwa, Paweł Petkow Dimitrow
BACKGROUND: Sudden cardiac death (SCD) risk stratification is the most important preventive action in patients with hypertrophic cardiomyopathy (HCM). The identification of the ischemia biomarker high sensitive troponin I (hs-TnI) role for this arrhythmic disease may provide additional information for SCD risk stratification. The aim of the study was to compare echocardiographic parameters (prognostic for risk stratification of SCD in HCM) among two subgroups of HCM patients: with elevated hs-TnI versus non-elevated hs-TnI level...
September 13, 2017: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28888482/exercise-training-and-cardiac-autonomic-function-in-type-2-diabetes-mellitus-a-systematic-review
#4
REVIEW
Pooja Bhati, Shweta Shenoy, M Ejaz Hussain
Cardiac autonomic neuropathy (CAN) is a common complication of type 2 diabetes mellitus (T2DM). It has been found to independently predict all cause and cardiovascular disease (CVD) mortality. It remains unclear whether exercise training could improve autonomic control in T2DM patients. The purpose of this study was to systematically review the effects of exercise training on cardiac autonomic function in T2DM patients. Electronic databases (MEDLINE, CENTRAL, PEDro, Scopus and Web of science) were systematically searched to retrieve relevant evidence...
September 6, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28871552/lessons-from-a-tarantula-new-insights-into-myosin-interacting-heads-motif-evolution-and-its-implications-on-disease
#5
REVIEW
Lorenzo Alamo, Antonio Pinto, Guidenn Sulbarán, Jesús Mavárez, Raúl Padrón
Tarantula's leg muscle thick filament is the ideal model for the study of the structure and function of skeletal muscle thick filaments. Its analysis has given rise to a series of structural and functional studies, leading, among other things, to the discovery of the myosin interacting-heads motif (IHM). Further electron microscopy (EM) studies have shown the presence of IHM in frozen-hydrated and negatively stained thick filaments of striated, cardiac, and smooth muscle of bilaterians, most showing the IHM parallel to the filament axis...
September 4, 2017: Biophysical Reviews
https://www.readbyqxmd.com/read/28862950/cardiac-adaptations-to-high-intensity-aerobic-training-in-premenopausal-and-recent-postmenopausal-women-the-copenhagen-women-study
#6
Jon Egelund, Peter G Jørgensen, Camilla M Mandrup, Thomas Fritz-Hansen, Bente Stallknecht, Jens Bangsbo, Michael Nyberg, Ylva Hellsten
BACKGROUND: We examined the role of menopause on cardiac dimensions and function and assessed the efficacy of exercise training before and after menopause. METHODS AND RESULTS: Two groups of healthy premenopausal (n=36, 49.4±0.3 years) and postmenopausal (n=37, 53.5±0.5 years) women with no history of cardiovascular disease and with a mean age difference between groups of only 4 years were studied. Cardiac dimensions and systolic and diastolic function were determined by transthoracic echocardiography with tissue Doppler imaging and 2-dimensional speckle tracking...
August 18, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28856140/new-insights-about-the-putative-role-of-myokines-in-the-context-of-cardiac-rehabilitation-and-secondary-cardiovascular-prevention
#7
REVIEW
Domenico Di Raimondo, Giuseppe Miceli, Gaia Musiari, Antonino Tuttolomondo, Antonio Pinto
Exercise training prevents the onset and the development of many chronic diseases, acting as an effective tool both for primary and for secondary prevention. Various mechanisms that may be the effectors of these beneficial effects have been proposed during the past decades: some of these are well recognized, others less. Muscular myokines, released during and after muscular contraction, have been proposed as key mediators of the systemic effects of the exercise. Nevertheless the availability of an impressive amount of evidence regarding the systemic effects of muscle-derived factors, few studies have examined key issues: (I) if skeletal muscle cells themselves are the main source of cytokine during exercise; (II) if the release of myokines into the systemic circulation reach an adequate concentration to provide significant effects in tissues far from skeletal muscle; (III) what may be the role carried out by muscular cytokine regarding the well-known benefits induced by regular exercise, first of all the anti-inflammatory effect of exercise...
August 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28837549/use-of-outpatient-cardiac-rehabilitation-among-heart-attack-survivors-20-states-and-the-district-of-columbia-2013-and-four-states-2015
#8
Jing Fang, Carma Ayala, Cecily Luncheon, Matthew Ritchey, Fleetwood Loustalot
Heart disease is the leading cause of death in the United States (1). Each year, approximately 790,000 adults have a myocardial infarction (heart attack), including 210,000 that are recurrent heart attacks (2). Cardiac rehabilitation (rehab) includes exercise counseling and training, education for heart-healthy living, and counseling to reduce stress. Cardiac rehab provides patients with education regarding the causes of heart attacks and tools to initiate positive behavior change, and extends patients' medical management after a heart attack to prevent future negative sequelae (3)...
August 25, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28803675/the-yale-fitness-intervention-trial-in-female-cancer-survivors-cardiovascular-and-physiological-outcomes
#9
M Tish Knobf, Sangchoon Jeon, Barbara Smith, Lyndsay Harris, Siobhan Thompson, Mitchel R Stacy, Karl Insogna, Albert J Sinusas
BACKGROUND: Induced premature menopause and cardio-toxic therapy increase cardiovascular disease risk in female cancer survivors. OBJECTIVE: To compare the effects of a 12 month aerobic-resistance fitness center intervention to home based physical activity on cardiovascular function and metabolic risk factors. METHODS: Subjects (N = 154) who had completed primary and/or adjuvant chemotherapy (past 3 years) were randomized to a fitness center intervention or a home based group...
August 10, 2017: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/28796004/effects-of-exercise-training-on-exercise-capacity-cardiac-function-bmi-and-quality-of-life-in-patients-with-atrial-fibrillation-a-meta-analysis-of-randomized-controlled-trials
#10
Michitaka Kato, Akira Kubo, Fumi Nihei, Michio Ogano, Hisato Takagi
Exercise training has become part of the standard care for patients with cardiovascular disease. We investigated the effects of exercise training on exercise capacity, cardiac function, BMI, and quality of life in patients with atrial fibrillation (AF). We searched for randomized-controlled trials of supervised exercise training versus care without exercise training (the control) in patients with permanent or nonpermanent AF published up to November 2016. Standard mean differences (SMD) or mean differences (MD), and 95% confidence intervals (CIs) were calculated using random-effect models...
September 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28762234/the-link-between-exercise-and-titin-passive-stiffness
#11
Sophie Lalande, Patrick J Mueller, Charles S Chung
What is the topic of this review? This review focuses on how in vivo and molecular measurements of cardiac passive stiffness can predict exercise tolerance and how exercise training can reduce cardiac passive stiffness. What advances does it highlight? This review highlights advances in understanding the relationship between molecular (titin-based) and in vivo (left ventricular) passive stiffness, how passive stiffness modifies exercise tolerance, and how exercise training may be therapeutic for cardiac diseases with increased passive stiffness...
September 1, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28757291/protein-aggregation-cardiovascular-diseases-and-exercise-training-where-do-we-stand
#12
Marisol Gouveia, Ke Xia, Wilfredo Colón, Sandra I Vieira, Fernando Ribeiro
Cells ensure their protein quality control through the proteostasis network. Aging and age-related diseases, such as neurodegenerative and cardiovascular diseases, have been associated to the reduction of proteostasis network efficiency and, consequently, to the accumulation of protein misfolded aggregates. The decline in protein homeostasis has been associated with the development and progression of atherosclerotic cardiovascular disease, cardiac hypertrophy, cardiomyopathies, and heart failure. Exercise training is a key component of the management of patients with cardiovascular disease, consistently improving quality of life and prognosis...
July 28, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28747269/high-intensity-interval-training-and-cardiac-autonomic-control-in-individuals-with-metabolic-syndrome-a-randomised-trial
#13
Joyce S Ramos, Lance C Dalleck, Fabio Borrani, Kassia S Beetham, Gregore Iven Mielke, Katrin A Dias, Matthew P Wallen, Shelley E Keating, Robert G Fassett, Jeff S Coombes
BACKGROUND: Insulin resistance has been postulated to play a central role in the co-appearance of various cardiovascular disease risk factors constituting the metabolic syndrome (MetS). There is evidence that altered cardiac autonomic function (CAF) may precede the onset of insulin resistance. Exercise training has been shown to improve CAF in different populations, yet little is known regarding the exercise dose response for CAF. The aim of this study was to investigate the impact of different volumes of high-intensity interval training (HIIT) and traditional moderate-intensity continuous training (MICT) on CAF in participants with MetS...
July 21, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28735757/the-influence-of-training-characteristics-on-the-effect-of-exercise-training-in-patients-with-coronary-artery-disease-systematic-review-and-meta-regression-analysis
#14
Jos J Kraal, Tom Vromen, Ruud Spee, Hareld M C Kemps, Niels Peek
BACKGROUND: Although exercise-based cardiac rehabilitation improves exercise capacity of coronary artery disease patients, it is unclear which training characteristic determines this improvement. Total energy expenditure and its constituent training characteristics (training intensity, session frequency, session duration and programme length) vary considerably among clinical trials, making it hard to compare studies directly. Therefore, we performed a systematic review and meta-regression analysis to assess the effect of total energy expenditure and its constituent training characteristics on exercise capacity...
July 18, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28719753/exercise-prescriptions-for-training-and-rehabilitation-in-patients-with-heart-and-lung-disease
#15
Pietro Palermo, Ugo Corrà
Rehabilitation in patients with advanced cardiac and pulmonary disease has been shown to increase survival and improve quality of life, among many other benefits. Exercise training is the fundamental ingredient in these rehabilitation programs. However, determining the amount of exercise is not straightforward or uniform. Most rehabilitation and training programs fix the time of exercise and set the exercise intensity to the goals of the rehabilitation program and the exercise-related hurdles of the individual...
July 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28705551/effects-of-progressive-resistance-training-on-cardiovascular-autonomic-regulation-in-patients-with-parkinson-disease-a-randomized-controlled-trial
#16
Hélcio Kanegusuku, Carla Silva-Batista, Tiago Peçanha, Alice Nieuwboer, Natan D Silva, Luiz A Costa, Marco T de Mello, Maria E Piemonte, Carlos Ugrinowitsch, Cláudia L Forjaz
OBJECTIVE: To evaluate the effects of a progressive resistance training (RT) on cardiac autonomic modulation and on cardiovascular responses to autonomic stress tests in patients with Parkinson disease (PD). DESIGN: Randomized clinical trial. SETTING: The Brazil Parkinson Association. PARTICIPANTS: Patients (N=30) with PD (modified Hoehn & Yahr stages 2-3) were randomly divided into 2 groups: a progressive RT group (PD training [PDT] group) and a control group (PD control [PDC] group)...
July 10, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28689854/impact-of-cardiac-rehabilitation-and-exercise-training-programs-in-coronary-heart-disease
#17
REVIEW
Sergey Kachur, Vasutakarn Chongthammakun, Carl J Lavie, Alban De Schutter, Ross Arena, Richard V Milani, Barry A Franklin
Cardiovascular rehabilitation (CR) is the process of developing and maintaining an optimal level of physical, social, and psychological well-being in order to promote recovery from cardiovascular (CV) illness. It is a multi-disciplinary approach encompassing supervised exercise training, patient counseling, education and nutritional guidance that may also enhance quality of life. Beneficial CV effects may include improving coronary heart disease risk factors; particularly exercise capacity, reversing cardiac remodeling, and favorably modifying metabolism and systemic oxygen transport...
June 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28682654/effect-of-exercise-training-on-cardiac-biomarkers-in-at-risk-populations-a-systematic-review
#18
Susan Sullivan Glenney, Derrick Paul Brockemer, Andy C Ng, Michael A Smolewski, Vladimir M Smolgovskiy, Adam S Lepley
BACKGROUND: Studies have demonstrated beneficial effects of exercise on cardiovascular disease (CVD) biomarkers for healthy individuals, however a comprehensive review regarding the effect of exercise on CVD biomarkers in at-risk populations is lacking. METHODS: Literature search was performed to identify studies meeting the following criteria: RCT; participants with pathology/activity limitations; biomarker outcome (total cholesterol, HDL, LDL, C-reactive protein, insulin, triglycerides, or glucose); exercise intervention...
July 6, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28677944/heart-rate-response-and-recovery-in-wheelchair-tetraplegic-rugby-athletes-a-pilot-study
#19
Michelle C Coutinho, Patrícia S Vigário, Agnaldo J Lopes, Fernando S Guimarães
BACKGROUND: Subjects with spinal cord injuries (SCI) have impaired autonomic cardiac regulation and increased risk of cardiovascular disease. In face of the insufficient research data on the autonomic control of physically active subjects with SCI, this study aimed at describing the chronotropic response, as well as the heart rate recovery behaviour of a cohort of elite wheelchair rugby athletes. METHODS: This is a cross-sectional study including a convenience sample of 17 elite wheelchair rugby athletes with tetraplegia...
July 5, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28666746/micrornas-as-important-regulators-of-exercise-adaptation
#20
REVIEW
Gustavo J J Silva, Anja Bye, Hamid El Azzouzi, Ulrik Wisløff
A significant body of evidence supports the protective role of exercise training (ET) in cardiovascular diseases, skeletal muscle dystrophies, several types of cancer, Alzheimer disease or even in the recovery of spinal cord injury. In spite of this, the molecular mechanisms underlying the beneficial effects of exercise training are not well understood and remain elusive. Several mechanisms have been proposed in the past, but more recently microRNAs (miRNAs), small non-coding RNA molecules involved in a variety of basic biological processes that negatively modulate gene expression, recognized as important regulatory molecules...
June 2017: Progress in Cardiovascular Diseases
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