Weili Liu, Hua Li, Yuan Gao, Xuelian Zhang, Zilin Wei, Dong Yang, Min Jin, Zhigang Qiu, Zhiqiang Shen, Zhaoli Chen, Yamei Qiao, Lingling Pu, Changqing Yan, Shuang Zhang, Xinxing Wang, Junwen Li
The composition, quantity, and function of peripheral blood mononuclear cells (PBMCs) are closely correlated with tumorigenesis. However, the mechanisms of PBMCs in lung cancer are not clear. Mitochondria are energy factories of cells, and almost all cellular functions rely on their energy metabolism level. The present study aimed to test whether the mitochondrial function of PBMCs directly determines their tumor immune monitoring function. We recruited 211 subjects, including 105 healthy controls and 106 patients with recently diagnosed with lung cancer...
April 11, 2024: International Immunopharmacology