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https://www.readbyqxmd.com/read/29925038/milestone-ratings-and-supervisory-role-categorizations-swim-together-but-is-the-water-muddy
#1
Daniel J Schumacher, Kathleen W Bartlett, Sean P Elliott, Catherine Michelson, Tanvi Sharma, Lynn C Garfunkel, Beth King, Alan Schwartz
PURPOSE: This single specialty, multi-institutional study aimed to determine: 1) the association between milestone ratings for individual competencies and average milestone ratings (AMRs) and 2) the association between AMRs and recommended supervisory role categorizations made by individual clinical competency committee (CCC) members. METHODS: During the 2015-16 academic year, CCC members at 14 pediatric residencies reported milestone ratings for 21 competencies and recommended supervisory role categories (may not supervise, may supervise in some settings, may supervise in all settings) for residents they reviewed...
June 17, 2018: Academic Pediatrics
https://www.readbyqxmd.com/read/29924893/reliability-of-heartsmap-as-a-tool-for-evaluating-psychosocial-assessment-documentation-practices-in-emergency-departments-for-pediatric-mental-health-complaints
#2
Carson Gill, Brendan Arnold, Sean Nugent, Alykhan Rajwani, Michael Xu, Tyler Black, Quynh Doan
OBJECTIVES: The goal of this study was to assess the reliability of HEARTSMAP as a standardized tool for evaluating the quality of psychosocial assessment documentation of pediatric mental health presentations to the emergency department. In addition, we report on current documentation practices. METHODS: We conducted a retrospective cross-sectional study of pediatric (up to age 17) mental health-related visits to four emergency departments between April 1, 2013 and March 31, 2014...
June 20, 2018: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29924758/non-syndromic-craniosynostosis-in-children-scoping-review
#3
A Garrocho-Rangel, L Manríquez-Olmos, J Flores-Velázquez, M-A Rosales-Berber, R Martínez-Rider, A Pozos-Guillén
BACKGROUND: Craniosynostosis (CS) is a complex condition consisting of the early fusion of one or more cranial sutures in the intrauterine stage. The affected infant exhibits abnormal head shape at time of birth or shortly thereafter. It can be observed in normal individuals (non-syndromic CS or NSCS) or as a part of a multisystem syndrome. The purposes of the present article were to carry out a scoping review on Non-Syndromic CS and to discuss the most important findings retrieved. MATERIAL AND METHODS: The steps of this scoping review were as follows: first, to pose a research question; second, to identify relevant studies to answer the research question; third, to select and retrieve the studies; fourth, to chart the critical data, and finally, to collate, summarize, and report the results from the most important articles...
June 20, 2018: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29923935/comparison-of-pediatric-cardiopulmonary-resuscitation-quality-in-classic-cardiopulmonary-resuscitation-and-extracorporeal-cardiopulmonary-resuscitation-events-using-video-review
#4
Mahsheed Taeb, Amanda B Levin, Michael C Spaeder, Jamie M Schwartz
OBJECTIVES: To assess differences in cardiopulmonary resuscitation quality in classic cardiopulmonary resuscitation versus extracorporeal cardiopulmonary resuscitation events using video recordings of actual pediatric cardiac arrest events. DESIGN: Single-center, prospective, observational trial. SETTING: Tertiary-care pediatric teaching hospital, cardiac ICU. PATIENTS: All patients admitted to the pediatric cardiac ICU with cardiopulmonary resuscitation events lasting greater than 2 minutes captured on video...
June 19, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29923367/cerebral-venous-sinus-thrombosis
#5
REVIEW
Marco Capecchi, Maria Abbattista, Ida Martinelli
The cerebral venous system is an unusual site of thrombosis, with a particularly high incidence in young adults. This incidence has increased in past decades because of the improvement of neuroradiological techniques. Risk factors for cerebral venous sinus thrombosis overlap with those of other venous thromboembolism sites, however, some are specific for this particular anatomical district. Prognosis is favorable in most cases if diagnosis is made rapidly and treatment is promptly initiated, even if acute complications or chronic invalidity still occur in a quarter of patients...
June 19, 2018: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29923253/comparison-of-survival-outcome-between-donor-types-or-stem-cell-sources-for-childhood-acute-myeloid-leukemia-after-allogenic-hematopoietic-stem-cell-transplantation-a-multicenter-retrospective-study-of-study-alliance-of-yeungnam-pediatric-hematology-oncology
#6
Ye Jee Shim, Jae Min Lee, Heung Sik Kim, Nani Jung, Young Tak Lim, Eu Jeen Yang, Jeong Ok Hah, Young-Ho Lee, Hee Won Chueh, Jae Young Lim, Eun Sil Park, Jeong A Park, Ji Kyoung Park, Sang Kyu Park
We compared transplant outcomes between donor types and stem cell sources for childhood acute myeloid leukemia (AML). The medical records of children with AML in the Yeungnam region of Korea from January 2000 to June 2017 were reviewed. In all, 76 children with AML (male-to-female ratio = 46:30) received allogenic hematopoietic stem cell transplantation (allo-HSCT). In total, 29 patients received HSCT from either a matched-related donor or a mismatched-related donor, 32 patients received an unrelated donor, and 15 patients received umbilical cord blood...
June 19, 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29923186/environmental-risk-factors-and-non-pharmacological-non-surgical-interventions-for-obesity-an-umbrella-review-of-meta-analyses-of-cohort-studies-and-randomized-controlled-trials
#7
REVIEW
Marco Solmi, Cristiano A Köhler, Brendon Stubbs, Ai Koyanagi, Beatrice Bortolato, Francesco Monaco, Davy Vancampfort, Myrela O Machado, Michael Maes, Ioanna Tzoulaki, Joseph Firth, John P A Ioannidis, André F Carvalho
BACKGROUND: Multiple environmental factors have been implicated in obesity and multiple interventions, besides drugs and surgery, have been assessed in obese patients. Results are scattered across many studies and meta-analyses and they often mix obese and overweight individuals. MATERIALS AND METHODS: PubMed and Cochrane Database of Systematic Reviews were searched through January 21st , 2017 for meta-analyses of cohort studies assessing environmental risk factors for obesity, and randomized controlled trials investigating non-pharmacological, non-surgical therapeutic interventions for obesity...
June 20, 2018: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29922984/neurocognitive-functioning-in-patients-with-22q11-2-deletion-syndrome-a-meta-analytic-review
#8
REVIEW
Paul J Moberg, Mara J Richman, David R Roalf, Chelsea L Morse, Anna C Graefe, Laura Brennan, Kayci Vickers, Wangchen Tsering, Vidyulata Kamath, Bruce I Turetsky, Ruben C Gur, Raquel E Gur
The 22q11.2 deletion syndrome (22q11.2DS) is a known risk factor for development of schizophrenia and is characterized by a complex neuropsychological profile. To date, a quantitative meta-analysis examining cognitive functioning in 22q11.2DS has not been conducted. A systematic review of cross-sectional studies comparing neuropsychological performance of individuals with 22q11.2DS with age-matched healthy typically developing and sibling comparison subjects was carried out. Potential moderators were analyzed...
June 19, 2018: Behavior Genetics
https://www.readbyqxmd.com/read/29922525/spanning-external-fixation-for-the-treatment-of-open-joint-injuries-in-pediatric-burn-patients
#9
Kelly Carmichael, Daniel Torres, Carlos J Jimenez, Matthew C Comley, Ernest B Evans
In this article, we report a case series on spanning external fixation for the treatment of open joint burn injuries in a pediatric population. We reviewed the case logs of all orthopedic surgeons from 2000 to 2010 at a burn hospital to identify pediatric patients with open joints secondary to burn injuries. Nine patients who sustained open joint injuries after a burn and treated with a spanning external fixator (SEF) were identified. Characteristics of the burns included: five elbow, four knee; seven flame, two electrical; average total body surface area affected 49...
April 16, 2018: Curēus
https://www.readbyqxmd.com/read/29922296/insights-gained-from-the-study-of-pediatric-systemic-lupus-erythematosus
#10
REVIEW
Mindy S Lo
The pathophysiology of systemic lupus erythematosus (SLE) has been intensely studied but remains incompletely defined. Currently, multiple mechanisms are known to contribute to the development of SLE. These include inadequate clearance of apoptotic debris, aberrant presentation of self nucleic antigens, loss of tolerance, and inappropriate activation of T and B cells. Genetic, hormonal, and environmental influences are also known to play a role. The study of lupus in children, in whom there is presumed to be greater genetic influence, has led to new understandings that are applicable to SLE pathophysiology as a whole...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29921249/robotic-enucleation-for-pediatric-insulinoma-with-men1-syndrome-a-case-report-and-literature-review
#11
Mei Liang, Jialin Jiang, Hongmei Dai, Xiafei Hong, Xianlin Han, Lin Cong, Anli Tong, Fang Li, Yaping Luo, Weinan Liu, Liangrui Zhou, Wenyu Di, Wenming Wu, Yupei Zhao
BACKGROUND: A patient with a rare pediatric insulinoma and MEN1 syndrome was treated by robotic enucleation surgery. CASE PRESENTATION: We present a case of a 9-year-old girl presenting with repeated loss of consciousness, concomitant with a pale face, palpitations, and convulsions, which had persisted for 2 years and had been aggravated during the previous 2 months. She was previously misdiagnosed with epilepsy in another hospital. We further examined her while she was hospitalized...
June 19, 2018: BMC Surgery
https://www.readbyqxmd.com/read/29921243/changing-outpatient-referral-patterns-in-a-small-pediatric-nephrology-practice
#12
Coral Hanevold, Susan Halbach, Jin Mou, Karyn Yonekawa
BACKGROUND: We have noted a large number of referrals for abnormal kidney imaging and laboratory tests and postulated that such referrals have increased significantly over time. Understanding changes in referral patterns is helpful in tailoring education and communication between specialists and primary providers. METHODS: We performed a retrospective chart review of new patient referrals to Mary Bridge Children's Nephrology clinic for early (2002 to 2004) and late (2011 to 2013) cohorts...
June 19, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29921210/off-label-use-of-drugs-and-adverse-drug-reactions-in-pediatric-units-a-prospective-multicenter-study
#13
Andrea D Pratico, Laura Longo, Silvana Mansueto, Lucia Gozzo, Ignazio Barberi, Venera Tiralongo, Vincenzo Salvo, Raffaele Falsaperla, Giovanna Vitaliti, Mario La Rosa, Antonio Rotondo, Nicoletta Avola, Debora Sgarlata, Annalisa Damiano, Massimo Tirantello, Gaspare Anzelmo, Domenico Cipolla, Angelo Rizzo, Antonio Russo, Martino Ruggieri, Salvatore Salomone, Filippo Drago
BACKGROUND: Given the growing use of off-label in pediatric practice, there is a growing interest on pharmacovigilance programs monitoring the occurrence of adverse drug reactions related to off-label drug prescription in childhood. PATIENTS AND METHODS: The results of a one-year program of pharmacovigilance issued in the Sicilian Region, Italy, are herein presented. The study involved 6 pediatric and neonatal centres and prospectively reviewed the prescriptions of 5,060 patients, who were stratified for age (newborn, infant, children, adolescents)...
June 19, 2018: Current Drug Safety
https://www.readbyqxmd.com/read/29921021/hepatosplenic-%C3%AE-%C3%AE-t-cell-lymphoma-of-two-adolescents-case-report-and-retrospective-literature-review-in-children-adolescents-and-young-adults
#14
Sheila S McThenia, Jawhar Rawwas, Jennifer L Oliveira, Shakila P Khan, Vilmarie Rodriguez
HSTCL is a highly aggressive malignancy with a poor prognosis. Case series and accounts have reported the use of different chemotherapy regimens with diverse patient outcomes. Most long-term survivors had undergone high-dose chemotherapy with autologous or allogeneic HCT. We describe two pediatric patients with HSTCL who were treated with chemotherapy followed by allogeneic HCT. Both patients are alive and in complete remission 2 and 8 years after therapy. Multiagent chemotherapy followed with allogeneic HCT seems to provide patients who have chemotherapy-sensitive disease a long-term disease-free survival...
June 19, 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29920880/effect-of-cyp3a5-1-expression-on-tacrolimus-required-dose-for-transplant-pediatrics-a-systematic-review-and-meta-analysis
#15
REVIEW
Fatemeh Hendijani, Negar Azarpira, Maryam Kaviani
This systematic review was designed to find out optimal tacrolimus dose in pediatrics according to their CYP3A5*1 genotype by performing meta-analysis. PubMed, Scopus, ISI web of Science, ProQuest, Cochrane library, and clinicaltrail.gov were systematically searched to find studies in which tacrolimus dose and/or blood concentration and/or concentration-to-dose (C/D) ratio were determined in genotype groups of CYP3A5*1 in pediatric population. Data were extracted at 14 time points post-transplantation and meta-analysis of mean and SD was performed...
June 19, 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29920709/management-of-pediatric-acute-hematogenous-osteomyelitis-part-i-antimicrobial-stewardship-approach-and-review-of-therapies-for-methicillin-susceptible-staphylococcus-aureus-streptococcus-pyogenes-and-kingella-kingae
#16
Kailynn J DeRonde, Jennifer E Girotto, David P Nicolau
Acute hematogenous osteomyelitis (AHO), often occurring in young children, is the most frequently diagnosed type of osteomyelitis in pediatric patients. Optimizing antibiotics is essential as delays to receipt of appropriate therapy can lead to chronic osteomyelitis, as well as impairments in bone growth and development. Antimicrobial Stewardship Programs (ASPs) are in a key position to help improve the care of patients with AHO as they contain a pharmacist with expertise in antibiotic drug selection, optimization of dosing, and microbiologic test review...
June 19, 2018: Pharmacotherapy
https://www.readbyqxmd.com/read/29920580/insights-from-the-geographic-spread-of-the-lyme-disease-epidemic
#17
Taylor Eddens, Daniel J Kaplan, Alyce J M Anderson, Andrew J Nowalk, Brian T Campfield
Background: Lyme disease is the most common reportable zoonotic infection in the United States. Recent data suggests spread of the Ixodes tick vector and increasing incidence of Lyme disease in several states, including Pennsylvania. We sought to determine the clinical presentation and healthcare utilization patterns for pediatric Lyme disease in western Pennsylvania. Methods: The electronic medical records of all patients with an ICD9 diagnosis of Lyme disease between 2003-2013 at Children's Hospital of Pittsburgh were individually reviewed for cases meeting the 2011 CDC case definition for Lyme disease...
June 16, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29920492/pediatric-intracranial-hydatid-cyst-a-case-series-with-literature-review
#18
Humam Tanki, Harshita Singh, Uday S Raswan, Abdul R Bhat, Altaf R Kirmani, Altaf U Ramzan
Hydatid disease is an endemic zoonotic disease in many areas of the world. An intracranial hydatid cyst is a relatively rare entity, accounting for only 1-2% of all intracranial space-occupying lesions. Most commonly they are seen in children and young adults. Here, we present 9 cases of pediatric intracranial hydatid cyst operated at Sher-I-Kashmir Institute of Medical Sciences, Srinagar, India, between 2009 and 2015. The mean age of presentation was 11.5 years. The male to female ratio was 5: 4. In 7 cases, a history of contact with pet dogs was present...
June 19, 2018: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29917225/psychological-treatments-for-adults-and-children-with-epilepsy-evidence-based-recommendations-by-the-international-league-against-epilepsy-psychology-task-force
#19
Rosa Michaelis, Venus Tang, Laura H Goldstein, Markus Reuber, William Curt LaFrance, Tobias Lundgren, Avani C Modi, Janelle L Wagner
Given the significant impact that psychosocial factors and epilepsy treatments can have on the health-related quality of life (HRQOL) of individuals with epilepsy and their families, there is great clinical interest in the role of psychological evaluation and treatments to improve HRQOL and comorbidities. Therefore, the International League Against Epilepsy (ILAE) charged the Psychology Task Force with the development of recommendations for clinical care based on evaluation of the evidence from their recent Cochrane review of psychological treatments in individuals with epilepsy...
June 19, 2018: Epilepsia
https://www.readbyqxmd.com/read/29917092/systematic-review-and-meta-analysis-of-controlled-intervention-studies-on-the-effectiveness-of-long-chain-omega-3-fatty-acids-in-patients-with-nonalcoholic-fatty-liver-disease
#20
Kathy Musa-Veloso, Carolina Venditti, Han Youl Lee, Maryse Darch, Seth Floyd, Spencer West, Ryan Simon
Context: Treatment options for nonalcoholic fatty liver disease (NAFLD) are needed. Objective: The aim of this review was to systematically assess the effects of omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFAs), particularly eicosapentaenoic acid and docosahexaenoic acid, on liver-related and metabolic outcomes in adult and pediatric patients with NAFLD. Data Sources: The online information service ProQuest Dialog was used to search 8 literature databases...
June 15, 2018: Nutrition Reviews
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