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https://www.readbyqxmd.com/read/27294709/twenty-years-of-mycobacterial-glycans-furanosides-and-beyond
#1
Todd L Lowary
The cell surface (or cell wall) of bacteria is coated with carbohydrate (or glycan) structures that play a number of important roles. These include providing structural integrity, serving as a permeability barrier to extracellular compounds (e.g., drugs) and modulating the immune system of the host. Of interest to this Account is the cell wall structure of mycobacteria. There are a host of different mycobacterial species, some of which cause human disease. The most well-known is Mycobacterium tuberculosis, the causative agent of tuberculosis...
July 19, 2016: Accounts of Chemical Research
https://www.readbyqxmd.com/read/27038773/a-stratified-myeloid-system-the-challenge-of-understanding-macrophage-diversity
#2
REVIEW
F Geissmann, E Mass
The present issue of 'Seminars in Immunology' addresses the topic of macrophage biology, 100 years after the death of Elie Metchnikoff (May 1845-July 1916). As foreseen by Metchnikoff, the roles of macrophages in the maintenance of homeostasis and immunity against pathogens have become a broad and active area of investigation. We now start to realize that the myeloid system includes a multiplicity of cell types with diverse developmental origins and functions. Therefore, the textbook picture of a plastic and multifunctional macrophage does not meet the requirements of our current knowledge anymore...
December 2015: Seminars in Immunology
https://www.readbyqxmd.com/read/25367978/prostate-cancer-immunotherapy-beyond-immunity-to-curability
#3
REVIEW
Jonathan W Simons
Metastatic prostate cancer is the second leading cause of death from cancer in the United States. It is the first prevalent cancer in which overall survival in advanced disease is modestly, but objectively, improved with outpatient delivered dendritic cell-based immunotherapy. More prostate cancer patients have enrolled through Facebook and trusted-site Internet searches in clinical trials for prostate cancer vaccine-based immunotherapy than in immunotherapy trials for lung, breast, colon, pancreas, ovarian, and bladder cancer combined in the past 7 years...
November 2014: Cancer Immunology Research
https://www.readbyqxmd.com/read/25188097/hematopathology-ss14-1-t-and-nk-cell-neoplasms-lessons-for-the-world-from-asia
#4
Shigeo Nakamura
The WHO classification of lymphoid neoplasms was published in 2001, then was updated in 2008, and will be evolving in the future. This classification is based on the disease discovery and accurate description by pathologists beyond the heterogeneity in the geographical distribution of the disease entities. It is now increasingly recognized that some peculiar T and NK cell lymphomas are largely prevalent in the East Asia as mostly represented by adult T-cell leukemia/lymphoma, NK/T-cell lymphoma, intestinal T-cell lymphoma, and chronic active EBV infection...
October 2014: Pathology
https://www.readbyqxmd.com/read/25168400/introduction-mechanisms-of-tissue-injury-in-autoimmune-diseases
#5
EDITORIAL
Dan Eilat
This issue of Seminars in Immunopathology is devoted to the most recent developments in our understanding of the mechanisms leading to tissue injury in autoimmune diseases. These include rheumatoid arthritis, systemic lupus erythematosus, type I diabetes, autoimmune liver diseases, inflammatory bowel diseases, autoimmune skin diseases, autoimmune uveitis, and autoinflammatory diseases. This impressive account of basic and clinical research in a wide spectrum of immunological disorders provides the reader with a comprehensive view of the common and unique features of these diverse conditions...
September 2014: Seminars in Immunopathology
https://www.readbyqxmd.com/read/24679963/seminars-in-immunology-new-vistas-on-nk-cell-development-and-function-preface
#6
Lorenzo Moretta
No abstract text is available yet for this article.
April 2014: Seminars in Immunology
https://www.readbyqxmd.com/read/24275600/overview-of-the-interleukin-1-family-of-ligands-and-receptors
#7
EDITORIAL
Charles A Dinarello
This issue of Seminars in Immunology on The Interleukin-1 (IL-1) Family of Ligands and Receptors updates the rapidly expanding importance of this family. There are individual chapters on IL-1α, IL-1β, processing and secretion of IL-1β, IL-18, IL-33, IL-36 and IL-37. In addition, a chapter of IL-1 decoy receptors, IL-1 signaling receptors and the clinical applications of IL-1 blockade in human disease is included. More than any other cytokine family, the IL-1 family is closely linked to innate inflammatory and immune responses...
December 15, 2013: Seminars in Immunology
https://www.readbyqxmd.com/read/24260725/what-taiwan-contributes-to-the-world-of-allergy-and-clinical-immunology
#8
Jiu-Yao Wang
In commemorate the 9th Asia Pacific Congress of Allergy, Asthma, and Clinical Immunology (APCAACI) in Taipei, Taiwan in November this year, some of the seminar works and contributions by the researchers from Taiwan to the advance in the field of allergy and clinical immunology, such as DNA vaccine, traditional Chinese medicine, anti-IgE antibody, and personalized medicine for severe drug allergic reaction, are summarized in this special review.
October 2013: Asia Pacific Allergy
https://www.readbyqxmd.com/read/23953334/a-50-year-journey-to-cure-childhood-acute-lymphoblastic-leukemia
#9
REVIEW
Ching-Hon Pui, William E Evans
The 50th anniversary of Seminars in Hematology coincides with the 50th anniversary of St. Jude Children's Research Hospital, and both milestones are inexorably linked to studies contributing to the cure of childhood acute lymphoblastic leukemia (ALL). We thought it fitting, therefore, to mark these events by traveling back in time to point out some of the achievements, institutions, study groups, and individuals that have made cure of childhood ALL a reality. In many instances, progress was driven by new ideas, while in others it was driven by new experimental tools that allowed more precise assessment of the biology of leukemic blasts and their utility in selecting therapy...
July 2013: Seminars in Hematology
https://www.readbyqxmd.com/read/23850297/seminars-in-immunology-technologies-and-opportunities-for-vaccines-introduction
#10
EDITORIAL
Rino Rappuoli
No abstract text is available yet for this article.
April 2013: Seminars in Immunology
https://www.readbyqxmd.com/read/23664513/selected-topics-of-the-4th-international-cooperative-study-group-meeting-on-immune-thrombocytopenia-revisited
#11
Urs E Nydegger, Lorenz Risch
The Intercontinental Cooperative immune thrombocytopenia (ITP) Study Group (ICIS) held its 4th Expert Meeting in September 2012 in Montreux, Switzerland. The program reunited researchers and clinicians from all over the globe and was organized with lectures and seminars for real-time exchange of latest information. Platelets target victims of autoimmune disease on their own, participating under physiological conditions in the immune network; these small cells are more immunologically savvy than previously thought...
January 2013: Seminars in Hematology
https://www.readbyqxmd.com/read/22737057/from-structure-to-solutions-the-role-of-basic-research-in-developing-anthrax-countermeasures-microbiology-graduate-program-seminar-anthrax-toxin
#12
Camille A Hardiman
Dr. John Collier traced the discoveries that elucidated the structure and function of the anthrax toxin in his talk "Anthrax Toxin," which was part of the Microbiology Graduate Program Seminar Series at Yale School of Medicine on February 23, 2012. Dr. Collier, Professor of Microbiology and Immunobiology at Harvard University, began by noting the advantages to studying anthrax pathogenesis in a biosafety level-1 lab. This designation does not merely facilitate his research, but also reflects a larger trend of basic research being leveraged to develop translational applications...
June 2012: Yale Journal of Biology and Medicine
https://www.readbyqxmd.com/read/22386796/understanding-the-complexity-of-ige-related-phenotypes-from-childhood-to-young-adulthood-a-mechanisms-of-the-development-of-allergy-medall-seminar
#13
REVIEW
Josep M Antó, Mariona Pinart, Mübeccel Akdis, Charles Auffray, Claus Bachert, Xavier Basagaña, Kai-Håkon Carlsen, Stefano Guerra, Leena von Hertzen, Sabina Illi, Francine Kauffmann, Thomas Keil, James P Kiley, Gerard H Koppelman, Christian Lupinek, Fernando D Martinez, Martijn C Nawijn, Dirkje S Postma, Valérie Siroux, Henriette A Smit, Peter J Sterk, Jordi Sunyer, Rudolf Valenta, Sergio Valverde, Cezmi A Akdis, Isabella Annesi-Maesano, Ferran Ballester, Marta Benet, Anne Cambon-Thomsen, Leda Chatzi, Jonathan Coquet, Pascal Demoly, Weiniu Gan, Judith Garcia-Aymerich, Elena Gimeno-Santos, Chantal Guihenneuc-Jouyaux, Tari Haahtela, Joachim Heinrich, Marie Herr, Cynthia Hohmann, Bénédicte Jacquemin, Jocelyne Just, Marjan Kerkhof, Manolis Kogevinas, Marek L Kowalski, Bart N Lambrecht, Susanne Lau, Karin C Lødrup Carlsen, Dieter Maier, Isabelle Momas, Patricia Noel, Sam Oddie, Susanna Palkonen, Isabelle Pin, Daniela Porta, Antonello Punturieri, Fanny Rancière, Robert A Smith, Barbara Stanic, Renato T Stein, Willem van de Veen, Antoon J M van Oosterhout, Raphaelle Varraso, Magnus Wickman, Cisca Wijmenga, John Wright, Gorkem Yaman, Torsten Zuberbier, Jean Bousquet
Mechanisms of the Development of Allergy (MeDALL), a Seventh Framework Program European Union project, aims to generate novel knowledge on the mechanisms of initiation of allergy. Precise phenotypes of IgE-mediated allergic diseases will be defined in MeDALL. As part of MeDALL, a scientific seminar was held on January 24, 2011, to review current knowledge on the IgE-related phenotypes and to explore how a multidisciplinary effort could result in a new integrative translational approach. This article provides a summary of the meeting...
April 2012: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/22359872/-chronologic-annotation-on-the-development-of-allergology-and-clinical-immunology-in-croatia
#14
Branimir Cvoriscec, Jasna Lipozencić, Asja Stipić Marković, Ivan Palecek
This issue of Acta Medica Croatica is dedicated to historical development and role of allergology and clinical immunology in Croatia. Also listed are the names of experts who have historically marked allergology and contributed to its development. Understanding the origin of allergies as immune phenomena occurred in Croatia simultaneously to many other European countries. The origin and development of institutions established in the early 1920s constituted the backbone of a solid vertical line, crucial for the development of allergology and immunology in Croatia during the past century...
2011: Acta Medica Croatica: C̆asopis Hravatske Akademije Medicinskih Znanosti
https://www.readbyqxmd.com/read/22253049/the-new-era-of-pompe-disease-advances-in-the-detection-understanding-of-the-phenotypic-spectrum-pathophysiology-and-management
#15
Priya S Kishnani, Alexandra A Beckemeyer, Nancy J Mendelsohn
Pompe disease is an autosomal recessive neuromuscular disorder marked by progressive muscle weakness due to lysosomal buildup of glycogen. Presentation is described as a spectrum, varying by age of onset, organ involvement, and degree of myopathy. Given the phenotypic variability, Pompe disease is broadly classified into an infantile form and a late onset (juvenile, childhood, adult onset) form. Prior to the advent of enzyme replacement therapy (ERT) with alglucosidase alfa and approval for human use in 2006, the natural history was limited due to death before age 2 years for infantile onset cases and significant morbidity and early mortality for late onset Pompe disease (LOPD)...
February 15, 2012: American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
https://www.readbyqxmd.com/read/22250435/-report-from-the-12th-tokai-chapter-educational-seminar-immunological-abnormalities-in-disorders-of-internal-medicine
#16
Tatsuo Ishizuka, Yoshitaka Fukuzawa, Takafumi Ando, Hidemi Goto, Yasushi Ohno, Yasuhiro Hakamata, Katsuhisa Matsumoto, Yasuomi Usui, Hiroyuki Morita, Zentaro Ohno
No abstract text is available yet for this article.
November 10, 2011: Nihon Naika Gakkai Zasshi. the Journal of the Japanese Society of Internal Medicine
https://www.readbyqxmd.com/read/21691035/kawasaki-disease-in-mongolia-results-from-2-nationwide-retrospective-surveys-1996-2008
#17
Dambadarjaa Davaalkham, Yosikazu Nakamura, Davaakhuu Baigalmaa, Gombojav Davaa, Ochir Chimedsuren, Nyamjav Sumberzul, Tserenkhuu Lkhagvasuren, Ritei Uehara, Hiroshi Yanagawa, Tomisaku Kawasaki
BACKGROUND: Kawasaki disease (KD) has been reported in many countries. However, the incidence of KD in Mongolia is not known. This is the first report of incident cases of KD in Mongolia, which were identified using data from 2 nationwide surveys. METHODS: Two nationwide retrospective surveys were conducted: medical histories were collected from patients aged 0 to 16 years who were hospitalized countrywide between 1996 and 2008. Hospital records for these patients were also reviewed...
2011: Journal of Epidemiology
https://www.readbyqxmd.com/read/21565925/recent-progress-in-carcinogenesis-progression-and-therapy-of-breast-cancer-the-20th-hiroshima-cancer-seminar-the-4th-three-universities-consortium-international-symposium-october-2010-31-october-2010-international-conference-center-hiroshima
#18
Masakazu Toi, Wataru Yasui, Hisao Ito, Eiichi Tahara
The 20th Hiroshima Cancer seminar focused upon breast cancer research and treatment particularly on the mechanism of tumorigenesis and drug resistance and development of novel therapeutics. Several molecules such as retinoblastoma and p16 were raised as key factors in tumorigenesis and invasiveness. Estrogen-related pathways seem to be closely involved in the process. For the tumor lacking hormone receptor and human epidermal growth factor 2, some other mechanisms could be responsible. It seems that MicroRNA 22 directing some putative targets such as SIRT1, Sp1 and CDK6 plays a crucial role in breast tumor growth and metastasis...
July 2011: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/20803837/preparing-online-students-for-comprehensive-examinations
#19
Michelle S Kanuth, E Camellia St John
OBJECTIVE: Identify and remedy difficulties in the preparation of online students for certification examination success. DESIGN: The final examination scores for the CLS Seminar course for the 2008 class of 27 on-campus and 10 online students were compared for statistical differences in seven examination areas. Problem areas were identified and changes in the CLS Seminar course were made in 2009 to improve the scores of the online students. The examination scores for the 2009 class of 33 on-campus and 10 online students were studied to determine improvement...
2010: Clinical Laboratory Science: Journal of the American Society for Medical Technology
https://www.readbyqxmd.com/read/19282026/graft-versus-host-disease
#20
REVIEW
James L M Ferrara, John E Levine, Pavan Reddy, Ernst Holler
Haemopoietic-cell transplantation (HCT) is an intensive therapy used to treat high-risk haematological malignant disorders and other life-threatening haematological and genetic diseases. The main complication of HCT is graft-versus-host disease (GVHD), an immunological disorder that affects many organ systems, including the gastrointestinal tract, liver, skin, and lungs. The number of patients with this complication continues to grow, and many return home from transplant centres after HCT requiring continued treatment with immunosuppressive drugs that increases their risks for serious infections and other complications...
May 2, 2009: Lancet
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