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https://www.readbyqxmd.com/read/28289843/micro-ct-evaluation-of-asymmetrical-ovine-intervertebral-disc-height-loss-from-surgical-approach
#1
Christopher Ludtka, Stefan Schwan, Andrea Friedmann, Walther Brehm, Ingo Wiesner, Felix Goehre
PURPOSE: The primary goal of this study is to clearly define and evaluate new intervertebral disc height parameters in analysing the morphological pathology of disc degeneration for application in damage model and regeneration therapy development, as well as applying traditional variables to 3-D characterization methods. METHODS: A posterolateral surgical approach was used to induce disc degeneration in an ovine model. At 12-months post-operation, sheep vertebral segments were removed and characterized using micro-CT to evaluate disc height parameters in regard to injury localization...
March 13, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28282064/predicting-the-risk-of-parafoveal-scotoma-in-myopic-normal-tension-glaucoma-role-of-optic-disc-tilt-and-rotation
#2
M S Sung, H Heo, Y S Ji, S W Park
PurposeThe purpose of the study was to evaluate the factors associated with development of parafoveal scotoma in early myopic normal tension glaucoma (NTG).Patients and methodsNinety-nine myopic NTG patients with mean deviation (MD) >-6.0 decibels (dB) were enrolled. Parafoveal scotoma was defined as a visual field (VF) defect within 10° of fixation with at least one point at P<1% lying at the four innermost central points. Systemic factors, optic disc characteristics including tilt ratio, rotation degree, β-zone parapapillary atrophy, disc hemorrhage, and peripapillary retinal nerve fiber layer and macular ganglion cell-inner plexiform layer (mGCIPL) thickness parameters using optical coherence tomography were evaluated...
March 10, 2017: Eye
https://www.readbyqxmd.com/read/28280945/influence-of-intraocular-pressure-reduction-on-progression-of-normal-tension-glaucoma-with-myopic-tilted-disc-and-associated-risk-factors
#3
Bo Ram Seol, Soa Kim, Dong Myung Kim, Ki Ho Park, Jin Wook Jeoung, Seok Hwan Kim
Purpose To evaluate the influence of intraocular pressure (IOP) reduction on progression of normal-tension glaucoma (NTG) with myopic tilted disc and to demonstrate the associated risk factors. METHODS: The medical records on 109 eyes of 109 NTG patients with myopic tilted discs who were followed up for more than 5 years and treated with topical medications were reviewed. Glaucoma progression was defined according to either structural or functional deterioration. Patients were divided into tertile groups according to the percent IOP reduction from the baseline, and the cumulative probability of NTG nonprogression of the upper- and lower-tertile groups was compared using Kaplan-Meier survival analysis...
March 9, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28265884/d%C3%A3-bridement-and-reconstrucion-improve-postoperative-sagittal-alignment-in-kyphotic-cervical-spinal-tuberculosis
#4
Zhimin Pan, Jiaquan Luo, Limin Yu, Yiwei Chen, Junlong Zhong, Zhiyun Li, Zhaoxun Zeng, Pingguo Duan, Yoon Ha, Kai Cao
BACKGROUND: Cervical spinal tuberculosis is relatively common in some developing countries. It erodes vertebrae and discs, which sometimes results in cervical kyphosis and myelopathy. However, to our knowledge, no studies have evaluated improvements to patient-reported outcomes among patients who undergo surgical cervical sagittal realignment after kyphotic cervical spinal tuberculosis has been treated by débridement and reconstruction. QUESTIONS/PURPOSES: (1) Can a spine with kyphotic cervical spinal tuberculosis be returned to normal alignment and fused successfully? (2) Will patient-reported outcomes be improved with this intervention? (3) Are patient-reported outcomes correlated with realignment? METHODS: Forty-six patients with kyphotic cervical spinal tuberculosis were evaluated in this retrospective study...
March 6, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28221329/relationship-between-anterior-lamina-cribrosa-surface-tilt-and-glaucoma-development-in-myopic-eyes
#5
Eun Jung Lee, Jong Chul Han, Changwon Kee
PURPOSE: To evaluate the anterior lamina cribrosa (LC) surface tilt angle in myopic eyes and associate it with glaucoma development. MATERIALS AND METHODS: In this retrospective study, medical records of myopic patients referred for glaucoma examination from July 1, 2012 to March 30, 2016 were reviewed. Comprehensive ophthalmic examination including spectral-domain optical coherence tomography were performed. We measured the angle of anterior LC surface tilt against Bruch's membrane opening from optical coherence tomography images at the center of the clinical optic disc margin...
February 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28178303/differentiation-of-glaucomatous-optic-discs-with-different-appearances-using-optic-disc-topography-parameters-the-glaucoma-stereo-analysis-study
#6
Masaki Tanito, Koji Nitta, Maki Katai, Yasushi Kitaoka, Yu Yokoyama, Kazuko Omodaka, Toru Nakazawa
The Glaucoma Stereo Analysis Study (GSAS) is a multicenter collaborative study of the characteristics of glaucomatous optic disc morphology using a stereo fundus camera. Using GSAS dataset, the formulas for predicting different glaucomatous optic disc appearances were established. The GSAS dataset containing three-dimensionally-analyzed optic disc topographic parameters from 187 eyes with primary open-angle glaucoma was assessed with discrimination analyses to obtain formulas predictive of glaucomatous optic disc appearances: focal ischemic (FI); generalized enlargement (GE), myopic glaucomatous (MY), and senile sclerotic (SS)...
2017: PloS One
https://www.readbyqxmd.com/read/28125859/visual-field-assessment-in-high-myopia-with-and-without-tilted-optic-disc
#7
Nasser Shoeibi, Nasrin Moghadas Sharif, Ramin Daneshvar, Asieh Ehsaei
BACKGROUND: The aim was to evaluate the effect of the tilted optic disc on the visual field in highly myopic eyes. METHODS: A total of 58 eyes from 58 highly myopic individuals underwent detailed ophthalmic examination and were categorised into two groups according to the presence of a tilted optic disc. The visual field of 20 eyes (mean age of 28.95 ± 7.22 years) with tilted optic discs were compared with 38 eyes (mean age of 27.87 ± 6.08 years) of control subjects without tilted optic discs using the 30-2 SITA standard protocol with a Humphrey Field Analyzer - HFA II-i...
January 26, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28114308/association-of-myopic-deformation-of-optic-disc-with-visual-field-progression-in-paired-eyes-with-open-angle-glaucoma
#8
Yu Sawada, Masanori Hangai, Makoto Ishikawa, Takeshi Yoshitomi
PURPOSE: The influence of myopia on glaucoma progression remains unknown, possibly because of the multifactorial nature of glaucoma and difficulty in assessing a solo contribution of myopia. The purpose of this study is to investigate the association of myopia with visual field (VF) progression in glaucoma using a paired-eye design to minimize the influence of confounding systemic factors that are diverse among individuals. METHODS: This retrospective study evaluated 144 eyes of 72 subjects with open-angle glaucoma, with similar intra-ocular pressure between paired eyes, spherical equivalent (SE) ≤ -2 diopter (D), and axial length ≥ 24 mm...
2017: PloS One
https://www.readbyqxmd.com/read/28050537/spinopelvic-balance-evaluation-of-patients-with-degenerative-spondylolisthesis-l4l5-and-l4l5-herniated-disc-who-underwent-surgery
#9
Viviane Regina Hernandez Nunes, Charbel Jacob, Igor Machado Cardoso, José Lucas Batista, Marcus Alexandre Novo Brazolino, Thiago Cardoso Maia
OBJECTIVE: To correlate spinopelvic balance with the development of degenerative spondylolisthesis and disk herniation. METHODS: This was a descriptive retrospective study that evaluated 60 patients in this hospital, 30 patients with degenerative spondylolisthesis at the L4-L5 level and 30 with herniated disk at the L4-L5 level, all of whom underwent Surgical treatment. RESULTS: Patients with lumbar disk herniation at L4-L5 level had a mean tilt of 8...
November 2016: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28046494/su-c-209-07-phantoms-for-digital-breast-tomosynthesis-imaging-system-evaluation
#10
D Jacobson, Y Liu
PURPOSE: Digital Breast Tomosynthesis (DBT) is gaining importance in breast imaging. There is a need for phantoms that can be used for image evaluation and comparison. Existing commercially available phantoms for DBT are expensive and may lack clinically relevant test objects. The purpose of this study is to develop phantoms for DBT evaluation. METHODS: Four phantoms have been designed and constructed to assess the image quality (IQ) of two DBT systems. The first contains a spiral of 0...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28003787/pseudoduplication-of-the-optic-disc-in-moderate-myopia
#11
Zeynep Eylül Ercan, Aylin Karalezli, Gokcen Coban
We report a case of optic disc pseudoduplication without pathological myopia. A 79-year-old woman presented with gradually decreased vision. Fundus examination showed macular drusen in both eyes and subretinal haemorrhage in the left eye. Both optic discs appeared to be tilted and the left optic disc was seen to be inferiorly duplicated. Pseudodoubling of the optic discs can be caused by optic disc and peripapillary chorioretinal colobomas and pathological myopia. Considering that our patient did not have enough axial length to merit a diagnosis of pathological myopia and no pathological fundus lesions typical of elongated sclera, we suggest that acquired pseudoduplication is not a condition unique to pathological myopia, but can occur in all myopic patients...
October 2016: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/27998660/prosthetic-dislocation-and-revision-after-primary-total-hip-arthroplasty-in-lumbar-fusion-patients-a-propensity-score-matched-pair-analysis
#12
Dean C Perfetti, Ran Schwarzkopf, Aaron J Buckland, Carl B Paulino, Jonathan M Vigdorchik
BACKGROUND: Lumbar-pelvic fusion reduces the variation in pelvic tilt in functional situations by reducing lumbar spine flexibility, which is thought to be important in maintaining stability of a total hip arthroplasty (THA). We compared dislocation and revision rates for patients with lumbar fusion and subsequent THA to a matched comparison cohort with hip and spine degenerative changes undergoing only THA. METHODS: We identified patients in New York State who underwent primary elective lumbar fusion for degenerative disc disease pathology and subsequent THA between January 2005 and December 2012...
November 23, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27989074/excellence-and-durability-a-normally-functioning-bj%C3%A3-%C3%A2-rk-shiley-flat-disc-prosthesis-42-years-post-implantation
#13
Armaan Shaikh, A Jamil Tajik
Mechanical heart valves have been used worldwide for more than 60 years. While the composition and design of the valves, and the surgical techniques employed to implant them, have changed and advanced over that time, some of the earlier mechanical heart valves showed such great durability that they are still functioning in patients today. One of the most often-used and long-lasting mechanical prostheses was the Björk-Shiley heart valve. While many versions of this valve were used during its 25 years of production, the most durable was the Björk-Shiley flat-disc valve...
March 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/27982204/corneal-structure-in-tilted-disc-syndrome
#14
Abuzer Gunduz, Nihat Polat, Tongabay Cumurcu, ErsinErsan Demirel, Ercan Özsoy
Purpose: To evaluate the central corneal thickness (CCT), corneal volume (CV), and anterior and posterior corneal surfaces using the Scheimpflug imaging system in patients diagnosed with tilted disc syndrome (TDS). Methods: The study group (Group 1) and the control group (Group 2) comprised 35 eyes of 35 age-, sex-, and refraction-matched cases. All cases underwent a full ophthalmic examination that included cycloplegic refraction, axial ocular length measurement, and Scheimpflug imaging...
September 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/27943601/surgical-repair-of-annulus-defect-with-biomimetic-multilamellar-nano-microfibrous-scaffold-in-a-porcine-model
#15
R Kang, H Li, Z Xi, S Ringgard, A Baatrup, K Rickers, M Sun, D Q S Le, M Wang, L Xie, Y Xie, M Chen, C Bünger
Annulus defect is associated with reherniation and disc degeneration after discectomy; currently there is no effective treatment that addresses this problem. The annulus is a hierarchical lamellar structure, where each lamella consists of aligned collagen fibers, which are parallel and tilted at 30° to the spinal axis. In this study, a biomimetic biodegradable scaffold consisting multi-lamella nano/microfibers, sharing nano-topography and micro-porosity similar to the native lamellar structure, was assessed in a porcine model, aided by sealing with fascia and medical glue and subsequent suture fixation...
December 11, 2016: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/27935604/ocular-characteristics-associated-with-the-location-of-focal-lamina-cribrosa-defects-in-open-angle-glaucoma-patients
#16
H-Yl Park, Y S Hwang, C K Park
PurposeTo investigate the clinical characteristics according to the location of focal lamina cribrosa (LC) defects and its associated ocular features.Patients and methodsA total of 139 open-angle glaucoma patients underwent Spectralis optical coherence tomography (OCT) with enhanced depth imaging. Alterations in the contour of the LC were investigated to find focal LC defects. The location of the visible LC defect from the neural canal wall (far-peripheral and mid-peripheral) and clock-hour position (superotemporal, temporal and inferotemporal) were classified...
December 9, 2016: Eye
https://www.readbyqxmd.com/read/27898445/pathologic-myopia
#17
REVIEW
Kyoko Ohno-Matsui
Pathologic myopia (PM) is the only myopia that causes the loss of best-corrected visual acuity. The main reason for best-corrected visual acuity loss is complications specific to PM, such as myopic maculopathy, myopic traction maculopathy, and myopic optic neuropathy (or glaucoma). The meta-analyses of the PM study group (META-PM study) made a classification system for myopic maculopathy. On the basis of this study, PM has been defined as eyes having atrophic changes equal to or more severe than diffuse atrophy...
November 2016: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/27847073/impingement-of-single-tilting-disc-mitral-prosthesis-during-transcatheter-aortic-valve%C3%A2-replacement
#18
John J Squiers, Katherine R Hebeler, J Michael DiMaio, Patrick Ogbue, Molly Szerlip, William T Brinkman
An 80-year-old woman with a medical history of mitral valve replacement with single-tilting disc prosthesis underwent transcatheter aortic valve replacement (TAVR). The tilting disc was noted to have abnormal motion after re-ballooning of the TAVR valve. Cardiopulmonary bypass was initiated, and the procedure was converted to surgical aortic valve replacement. After removal of the TAVR valve, the tilting disc moved freely. Although TAVR in patients with mitral prostheses is technically feasible, particular caution is necessary, and postdeployment dilation should be avoided...
December 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27837279/optic-disc-and-peripapillary-retinal-nerve-fiber-layer-characteristics-associated-with-glaucomatous-optic-disc-in-young-myopia
#19
Jong Eun Lee, Kyung Rim Sung, Ji Min Park, Joo Young Yoon, Sung Yong Kang, Sung Bae Park, Hyung Jin Koo
PURPOSE: To explore optic disc and peripapillary retinal nerve fiber layer (RNFL) features associated with glaucomatous optic disc (GOD) in young myopia. METHODS: Presence of GOD, optic disc tilt, and disc torsion were determined using fundus photographs. If the measured disc tilt ratio was >1.3, the optic disc was classified as tilted. Optic disc torsion was defined as a >15° deviation in the long axis of the optic disc from the vertical meridian. The average and four quadrants RNFL thicknesses were assessed using spectral domain optical coherence tomography (SD-OCT)...
March 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27820904/morphology-of-cyprid-attachment-organs-compared-across-disparate-barnacle-taxa-does-it-relate-to-habitat
#20
Hamad Al-Yahya, Hsi-Nien Chen, Benny K K Chan, Ryusuke Kado, Jens T Høeg
This study used morphometric analyses to compare the structure of the third antennular segment, also called the attachment organ, in cyprid larvae from cirripede species representing a diverse set of taxonomic groups. The aim was to investigate the degree of morphological variation in view of the diversity of habitats, settlement substrata, and modes of life found in the Cirripedia. In all cyprids the third segment features a flat surface (the attachment disc) covered with small cuticular villi thought to function in adhesion...
October 2016: Biological Bulletin
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