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https://www.readbyqxmd.com/read/27925706/influence-of-temperature-and-brewing-time-of-nettle-urtica-dioica-l-infusions-on-vitamin-c-content
#1
Jolanta Wolska, Michał Czop, Karolina Jakubczyk, Katarzyna Janda
Background: Stinging nettle (Urtica dioica L.) can be found in temperate climate zones of Europe, Africa and America Nettle may be a source of nutritional ingredients, mineral salts, vitamins and antioxidants. Objective: The aim of the study was to determine the effect of temperature and brewing time Urtica dioica L. infusions from different parts of this plant on vitamin C (ascorbic acid) content. Material and methods: Infusions of nettle leaf, stem and root were prepared at room temperature, 50°C, 60°C, 70°C and 80°C for 10 minutes...
2016: Roczniki Państwowego Zakładu Higieny
https://www.readbyqxmd.com/read/27919809/effect-of-novel-bioactive-edible-coatings-based-on-jujube-gum-and-nettle-oil-loaded-nanoemulsions-on-the-shelf-life-of-beluga-sturgeon-fillets
#2
Seyed Mohammad Taghi Gharibzahedi, Sara Mohammadnabi
Effect of jujube gum (JG; 4, 8 and 12% wt)-based nanoemulsions (NEs) containing nettle essential oil (NEO; 2, 3.5 and 5% wt) as new edible coatings was investigated to preserve Beluga sturgeon fillets (BSFs) during 15 day-refrigerated storage at 4°C. Physical (weight loss, cooking loss, color and texture), chemical (pH, FFA, PV, TBARS and TVB-N), microbiological (total and psychrotrophic bacterial counts), and sensorial characteristics of BSFs were kinetically analyzed. Preliminary studies showed that the NEs formulated with NEO lower than 5% at all JG concentrations were able to form stable coating solutions owing to the highest short-term stability (>90%) and entrapment efficiency (94...
December 2, 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27919657/synthesis-of-novel-steroidal-agonists-partial-agonists-and-antagonists-for-the-glucocorticoid-receptor
#3
Zhuang Jin, Hua Lin, Sathish Srinivasan, Jerome C Nwachukwu, Nelson Bruno, Patrick R Griffin, Kendall W Nettles, Theodore M Kamenecka
Adverse effects of glucocorticoids could be limited by developing new compounds that selectively modulate anti-inflammatory activity of the glucocorticoid receptor (GR). We have synthesized a novel series of steroidal GR ligands, including potent agonists, partial agonists and antagonists with a wide range of effects on inhibiting secretion of interleukin-6. Some of these new ligands were designed to directly impact conformational stability of helix-12, in the GR ligand-binding domain (LBD). These compounds modulated GR activity and glucocorticoid-induced gene expression in a manner that was inversely correlated to the degree of inflammatory response...
November 15, 2016: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/27891221/brood-size-moderates-associations-between-relative-size-telomere-length-and-immune-development-in-european-starling-nestlings
#4
Daniel Nettle, Clare Andrews, Sophie Reichert, Tom Bedford, Annie Gott, Craig Parker, Claire Kolenda, Carmen Martin-Ruiz, Pat Monaghan, Melissa Bateson
For young birds in a nest, body size may have implications for other aspects of development such as telomere length and immune function. However, it is possible to predict associations in either direction. On the one hand, there may be trade-offs between growth and telomere maintenance, and growth and investment in immune function, suggesting there will be negative correlations. On the other hand, relatively larger individuals might be advantaged in competition with their nest-mates, allowing them to garner more resources overall, leading to positive correlations...
November 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/27870835/full-antagonism-of-the-estrogen-receptor-without-a-prototypical-ligand-side-chain
#5
Sathish Srinivasan, Jerome C Nwachukwu, Nelson E Bruno, Venkatasubramanian Dharmarajan, Devrishi Goswami, Irida Kastrati, Scott Novick, Jason Nowak, Valerie Cavett, Hai-Bing Zhou, Nittaya Boonmuen, Yuechao Zhao, Jian Min, Jonna Frasor, Benita S Katzenellenbogen, Patrick R Griffin, John A Katzenellenbogen, Kendall W Nettles
Resistance to endocrine therapies remains a major clinical problem for the treatment of estrogen receptor-α (ERα)-positive breast cancer. On-target side effects limit therapeutic compliance and use for chemoprevention, highlighting an unmet need for new therapies. Here we present a full-antagonist ligand series lacking the prototypical ligand side chain that has been universally used to engender antagonism of ERα through poorly understood structural mechanisms. A series of crystal structures and phenotypic assays reveal a structure-based design strategy with separate design elements for antagonism and degradation of the receptor, and access to a structurally distinct space for further improvements in ligand design...
November 21, 2016: Nature Chemical Biology
https://www.readbyqxmd.com/read/27859808/diet-assessment-of-the-atlantic-sea-nettle-chrysaora-quinquecirrha-in-barnegat-bay-new-jersey-using-next-generation-sequencing
#6
Robert W Meredith, John J Gaynor, Paul A X Bologna
Next generation sequencing (NGS) methodologies have proven useful in deciphering the food items of generalist predators, but have yet to be applied to gelatinous animal gut and tentacle content. NGS can potentially supplement traditional methods of visual identification. Chrysaora quinquecirrha (Atlantic sea nettle) has progressively become more abundant in Mid-Atlantic United States' estuaries including Barnegat Bay (New Jersey), potentially having detrimental effects on both marine organisms and human enterprises...
November 17, 2016: Molecular Ecology
https://www.readbyqxmd.com/read/27788883/urtica-dioica-pollen-allergy-clinical-biological-and-allergomics-analysis
#7
Angelica Tiotiu, Andrea Brazdova, Cyril Longé, Patrice Gallet, Martine Morisset, Virginie Leduc, Christiane Hilger, Cédric Broussard, Rémy Couderc, Jean-Pierre Sutra, Hélène Sénéchal, Pascal Poncet
BACKGROUND: The most emblematic members of Urticaceae at allergic risk level are wall pellitories (Parietaria), whereas nettle (Urtica) pollen is considered as poorly allergenic. No allergen from nettle pollen has yet been characterized, whereas 4 are listed for Parietaria pollen by the International Union of Immunological Societies. Clinical and biological profiles of 2 adult men who developed symptoms against nettle pollen and/or leaves were studied. OBJECTIVE: To characterize the allergic reaction and identify the potential nettle pollen sensitizing allergens...
November 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27775975/the-scourge-of-the-spurge-family-an-imitator-of-rhus-dermatitis
#8
Kimberly A Huerth, Jason E Hawkes, Laurence J Meyer, Douglas L Powell
The Euphorbiaceae family (commonly known as "spurge") is a large, diverse, and widely distributed family of plants that encompass around 300 genera and more than 8000 species. Their attractiveness and hearty nature have made them popular for both indoor ornamentation and outdoor landscaping. Despite their ubiquity, the potential to cause irritant contact dermatitis (ICD) is often overlooked in favor of more notorious causes of phytodermatitis, namely, Toxicodendron species and nettles. We examined case reports spanning 40 years and discovered that spurge-induced ICD tends to befall children and middle-aged adults who unwittingly encounter the plant through play or horticulture, respectively...
November 2016: Dermatitis
https://www.readbyqxmd.com/read/27766153/physiological-stress-response-reflex-impairment-and-delayed-mortality-of-white-sturgeon-acipenser-transmontanus-exposed-to-simulated-fisheries-stressors
#9
Montana F McLean, Kyle C Hanson, Steven J Cooke, Scott G Hinch, David A Patterson, Taylor L Nettles, Matt K Litvak, Glenn T Crossin
White sturgeon (Acipenser transmontanus) are the largest freshwater fish in North America and a species exposed to widespread fishing pressure. Despite the growing interest in recreational fishing for white sturgeon, little is known about the sublethal and lethal impacts of angling on released sturgeon. In summer (July 2014, mean water temperature 15.3°C) and winter (February 2015, mean water temperature 6.6°C), captive white sturgeon (n = 48) were exposed to a combination of exercise and air exposure as a method of simulating an angling event...
2016: Conservation Physiology
https://www.readbyqxmd.com/read/27752448/accumulation-and-variability-of-maize-pollen-deposition-on-leaves-of-european-lepidoptera-host-plants-and-relation-to-release-rates-and-deposition-determined-by-standardised-technical-sampling
#10
Frieder Hofmann, Maren Kruse-Plass, Ulrike Kuhn, Mathias Otto, Ulrich Schlechtriemen, Boris Schröder, Rudolf Vögel, Werner Wosniok
BACKGROUND: Risk assessment for GMOs such as Bt maize requires detailed data concerning pollen deposition onto non-target host-plant leaves. A field study of pollen on lepidopteran host-plant leaves was therefore undertaken in 2009-2012 in Germany. During the maize flowering period, we used in situ microscopy at a spatial resolution adequate to monitor the feeding behaviour of butterfly larvae. The plant-specific pollen deposition data were supplemented with standardised measurements of pollen release rates and deposition obtained by volumetric pollen monitors and passive samplers...
2016: Environmental Sciences Europe
https://www.readbyqxmd.com/read/27713992/in-vitro-bioaccessibility-transepithelial-transport-and-antioxidant-activity-of-urtica-dioica-l-phenolic-compounds-in-nettle-based-food-products
#11
Gianpiero Bonetti, Paola Tedeschi, Giuseppe Meca, Davide Bertelli, Jordi Mañes, Vincenzo Brandolini, Annalisa Maietti
Nettle (Urtica dioica L.) is a well-known plant with a wide historical background use of stems, roots and leaves. Nettle leaves are an excellent source of phenolic compounds, principally 3-caffeoylquinic acid (3-CQA), caffeoylmalic acid (CMA) and rutin. The aim of this work was to evaluate the bioaccessibility (BAC), the bioavailability (BAV) and the antioxidant activity of nettle phenolic compounds present in foods and supplements. The BAC of nettle phenolics was evaluated with an in vitro dynamic digestion of real food matrices: the type of food matrix and chemical characteristic affected the kinetics of release and solubilization, with the highest BAC after duodenal digestion...
October 12, 2016: Food & Function
https://www.readbyqxmd.com/read/27688974/evaluation-of-the-effectiveness-of-insecticide-trunk-injections-for-control-of-latoia-lepida-cramer-in-the-sweet-olive-tree-osmanthus-fragrans
#12
Jun Huang, Juan Zhang, Yan Li, Jun Li, Xiao-Hua Shi
The screening of suitable insecticides is a key factor in successfully applying trunk injection technology to ornamental plants. In this study, six chemical pesticides were selected and injected into the trunks of Osmanthus fragrans to control the nettle caterpillar, Latoia lepida (Lepidoptera: Limacodidae), using a no-pressure injection system. The absorption rate of the insecticides, the leaf loss due to insect damage, and the mortality and frass amount of L. lepida larvae were evaluated after 77 and 429 days...
2016: PeerJ
https://www.readbyqxmd.com/read/27686361/review-of-daniel-nettle-s-tyneside-neighborhood-deprivation-social-life-and-social-behavior-in-one-british-city-open-book-2015
#13
Benjamin Campbell
No abstract text is available yet for this article.
September 29, 2016: Human Nature: An Interdisciplinary Biosocial Perspective
https://www.readbyqxmd.com/read/27679811/adult-neurogenesis-in-the-female-mouse-hypothalamus-estradiol-and-high-fat-diet-alter-the-generation-of-newborn-neurons-expressing-estrogen-receptor-%C3%AE
#14
Elizabeth P Bless, Jane Yang, Kalpana D Acharya, Sabin A Nettles, Fair M Vassoler, Elizabeth M Byrnes, Marc J Tetel
Estrogens and leptins act in the hypothalamus to maintain reproduction and energy homeostasis. Neurogenesis in the adult mammalian hypothalamus has been implicated in the regulation of energy homeostasis. Recently, high-fat diet (HFD) and estradiol (E2) have been shown to alter cell proliferation and the number of newborn leptin-responsive neurons in the hypothalamus of adult female mice. The current study tested the hypothesis that new cells expressing estrogen receptor α (ERα) are generated in the arcuate nucleus (ARC) and the ventromedial nucleus of the hypothalamus (VMH) of the adult female mouse, hypothalamic regions that are critical in energy homeostasis...
July 2016: ENeuro
https://www.readbyqxmd.com/read/27674877/head-and-neck-lymphedema-reducing-a-growing-problem
#15
M K Nettles, M Pishgou, C A Solares, J Brown, M Salgueiro, J K Byrd, M Groves, S Shaaban, S Reyes, K Ciarrocca, F Mott, G Postma, S DeRossi, S Kountakis, W F Mourad, B M Rabatic
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27565659/percutaneous-image-guided-pelvic-procedures-in-women-with-gynecologic-cancers-utilization-complications-and-impact-on-patient-management
#16
Rubina Zahedi, Shitanshu Uppal, Mishal Mendiratta-Lala, Ellen J Higgins, Ashley N Nettles, Katherine E Maturen
PURPOSE: Image-guided percutaneous pelvic procedures often play an important role in the management of women with gynecologic cancers. The purpose of this study is to evaluate the utilization of and indications for these procedures, and quantify their impact on patient management. METHODS: IRB-approved retrospective record review of percutaneous pelvic procedures requested by gynecologic oncology, 2005 to 2015. Descriptive statistics and logistic regression were performed...
August 27, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27561996/on-resonance-fluorescence-resonance-rayleigh-scattering-and-ratiometric-resonance-synchronous-spectroscopy-of-molecular-and-quantum-dot-fluorophores
#17
Kumudu Siriwardana, Charles B Nettles, Buddhini C N Vithanage, Yadong Zhou, Shengli Zou, Dongmao Zhang
Existing studies on molecular fluorescence have almost exclusively been focused on Stokes-shifted fluorescence spectroscopy (SSF) in which the emitted photon is detected at the wavelengths longer than that for the excitation photons. Information on fluorophore on-resonance fluorescence (ORF) and resonance Rayleigh scattering (RRS) is limited and often problematic due to the complex interplay of the fluorophore photon absorption, ORF emission, RRS, and solvent Rayleigh scattering. Reported herein is a relatively large-scale systematic study on fluorophore ORF and RRS using the conventional UV-vis extinction and SSF measurements in combination with the recently reported ratiometric resonance synchronous spectroscopic (R2S2, pronounced as "R-Two-S-Two") method...
September 20, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27464638/food-insecurity-as-a-driver-of-obesity-in-humans-the-insurance-hypothesis
#18
Daniel Nettle, Clare Andrews, Melissa Bateson
Integrative explanations of why obesity is more prevalent in some sectors of the human population than others are lacking. Here, we outline and evaluate one candidate explanation, the insurance hypothesis (IH). The IH is rooted in adaptive evolutionary thinking: the function of storing fat is to provide a buffer against shortfall in the food supply. Thus, individuals should store more fat when they receive cues that access to food is uncertain. Applied to humans, this implies that an important proximate driver of obesity should be food insecurity rather than food abundance per se...
July 28, 2016: Behavioral and Brain Sciences
https://www.readbyqxmd.com/read/27424771/chitosan-films-incorporated-with-nettle-urtica-dioica-l-extract-loaded-nanoliposomes-i-physicochemical-characterisation-and-antimicrobial-properties
#19
Sara Haghju, Sara Beigzadeh, Hadi Almasi, Hamed Hamishehkar
The objective of this study was to characterise and compare physical, mechanical and antimicrobial properties of chitosan-based films, containing free or nanoencapsulated nettle (Urtica dioica L.) extract (NE) at concentrations of 0, 0.5, 1 and 1.5% w/w. Nanoliposomes were prepared using soy-lecithin by thin-film hydration and sonication method to generate an average size of 107-136 nm with 70% encapsulation efficiency. The information on FT-IR reflected that some new interaction have occurred between chitosan and nanoliposomes...
July 17, 2016: Journal of Microencapsulation
https://www.readbyqxmd.com/read/27416783/chitosan-films-incorporated-with-nettle-urtica-dioica-l-extract-loaded-nanoliposomes-ii-antioxidant-activity-and-release-properties
#20
Hadi Almasi, Mohsen Zandi, Sara Beigzadeh, Sara Haghju, Nazila Mehrnow
Chitosan films were loaded with NE nettle (Urtica dioica L.) extract (NE) at concentrations of 0, 0.5, 1 and 1.5%w/w in the free or nanoliposomal form to obtain active and nanoactive films, respectively. The antioxidant potential of the films containing NE-loaded nanoliposomes was decreased in comparison of free NE incorporated films. Diffusion of NE to soybean oil was enough to delay the induction of the oxidation of soybean oil stored for 60 days in contact with chitosan based films. Release studies indicated that the release rate of NE in 95% ethanol simulant significantly decreased by the nanoencapsulation of NE...
July 14, 2016: Journal of Microencapsulation
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