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cryptoxanthin

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https://www.readbyqxmd.com/read/29785849/dietary-carotenoid-roles-in-redox-homeostasis-and-human-health
#1
Marcelo Paes Barros, Maria J Rodrigo, Lorenzo Zacarias
Classic nutrition believed that healthy diets should simply provide sufficient antioxidant loads to organisms, to hamper free radical processes and avoid oxidative stress. Current redox biology was proven much more intricate. Carotenoids are bioactive compounds in human diet with a multifaceted role in redox metabolism. This review discusses the participation of α/β-carotene, lutein, zeaxanthin, lycopene, β-cryptoxanthin, astaxanthin, and derivatives in redox homeostasis focusing on: (i) their anti-/pro-oxidant activities; (ii) control of gene expression via Nrf2-Keap1 and NF-ΚB pathways; and (iii) their link with (sub)cellular redox circuits, as part of the 'redox code' that orchestrates physiological processes and health in humans...
May 22, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29767694/shorter-time-to-pregnancy-with-increasing-preconception-carotene-concentrations-among-women-with-1-to-2-previous-pregnancy-losses
#2
Keewan Kim, Enrique F Schisterman, Robert M Silver, Brian D Wilcox, Anne M Lynch, Neil J Perkins, Richard W Browne, Laurie L Lesher, Joseph B Stanford, Aijun Ye, Jean Wactawski-Wende, Sunni L Mumford
Although maternal nutrition may impact fecundity, associations between preconception micronutrients and time to pregnancy (TTP) has not been examined. We assessed the relationship between preconception fat-soluble micronutrient concentrations and TTP among women with 1-2 prior pregnancy losses. This is a prospective cohort study of 1,228 women set in the EAGeR Trial (US, 2007-2011), which assessed the effect of preconception-initiated daily low dose aspirin on reproductive outcomes. We measured preconception zeaxanthin, cryptoxanthin, lycopene, α- and β-carotene, and α- and γ-tocopherol in serum...
May 14, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29751912/%C3%AE-cryptoxanthin-is-more-bioavailable-in-humans-from-fermented-orange-juice-than-from-orange-juice
#3
Dámaso Hornero-Méndez, Isabel Cerrillo, Ángeles Ortega, María-Rosario Rodríguez-Griñolo, Blanca Escudero-López, Franz Martín, María-Soledad Fernández-Pachón
Carotenoids, especially β-cryptoxanthin, exert multiple biological activities in the organism. Various processing techniques can improve carotenoid bioavailability in relation to the food matrix. The study objective was to compare the bioavailability of carotenoids from orange juice (OJ) with that from a beverage obtained by alcoholic fermentation of orange juice (FOB). Seven volunteers were recruited for a randomized, controlled, and crossover study. Post-intake plasma carotenoid concentrations were measured by HPLC in the subjects at 0-8 h after their consumption of OJ or FOB...
October 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29746108/screening-and-assessment-of-low-molecular-weight-biomarkers-of-milk-from-cow-and-water-buffalo-an-alternative-approach-for-the-rapid-identification-of-adulterated-water-buffalo-mozzarellas
#4
Chiara Dal Bosco, Stefania Panero, Maria Assunta Navarra, Pierpaolo Tomai, Roberta Curini, Alessandra Gentili
Adulteration of Mozzarella di Bufala Campana with cow milk is a common fraud because of high price and limited seasonal availability of water buffalo milk. In order to identify such adulteration, this work proposes a novel approach based on the use of low molecular weight biomarkers (LMWBs) species-specific. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) screening analyses identified β-carotene, lutein and β-cryptoxanthin as LMWBs of cow milk, while ergocalciferol was found only in water buffalo milk...
May 10, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29719199/antioxidants-linked-with-physical-cognitive-and-psychological-frailty-analysis-of-candidate-biomarkers-and-markers-derived-from-the-mark-age-study
#5
M Liset Rietman, Annemieke M W Spijkerman, Albert Wong, Harry van Steeg, Alexander Bürkle, María Moreno-Villanueva, Thilo Sindlinger, Claudio Franceschi, Beatrix Grubeck-Loebenstein, Jürgen Bernhardt, P Eline Slagboom, Olivier Toussaint, Florence Debacq-Chainiaux, Ewa Sikora, Efstathios S Gonos, Nicolle Breusing, Wolfgang Stuetz, Daniela Weber, Tilman Grune, Andrea Basso, Francesco Piacenza, Marco Malavolta, Sebastiano Collino, Eugene H J M Jansen, W M Monique Verschuren, Martijn E T Dollé
Frailty among elderly people leads to an increased risk for negative health outcomes. To prevent frailty, we need a better understanding of the underlying mechanisms and early detection of individuals at risk. Both may be served by identifying candidate (bio)markers, i.e. biomarkers and markers, for the physical, cognitive, and psychological frailty domains. We used univariate (Rank-ANOVA) and multivariate (elastic net) approaches on the RASIG study population (age range: 35-74 years, n = 2220) of the MARK-AGE Study to study up to 331 (bio)markers between individuals with and without frailty for each domain...
April 29, 2018: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/29696082/oxidant-status-iron-homeostasis-and-carotenoid-levels-of-copd-patients-with-advanced-disease-and-ltot
#6
M Kentson, P Leanderson, P Jacobson, H L Persson
Background : The pathogenesis of chronic obstructive pulmonary disease (COPD) is associated with oxidative stress. Both iron (Fe) and oxygen are involved in the chemical reactions that lead to increased formation of reactive oxygen species. Oxidative reactions are prevented by antioxidants such as carotenoids. Objective : To study the differences in Fe status, carotenoid levels, healthy eating habits, and markers of inflammation and oxidative damage on proteins in subjects with severe COPD ± long-term oxygen therapy (LTOT) and lung-healthy control subjects...
2018: European Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29695195/serum-levels-of-carotenoids-in-patients-with-osteonecrosis-of-the-femoral-head-are-lower-than-in-healthy-community-living-people
#7
Toshiaki Okura, Taisuke Seki, Koji Suzuki, Naoki Ishiguro, Yukiharu Hasegawa
PURPOSE: Oxidative stress is closely associated with the pathogenesis of nontraumatic osteonecrosis of the femoral head (ONFH). This study aimed to determine whether the serum levels of antioxidant nutrients were decreased in patients with ONFH. METHODS: We analyzed the serum levels of antioxidant nutrients in 39 patients with ONFH (ONFH group) and 78 age- and gender-matched healthy people (control group) who voluntarily participated in the Yakumo study, which is a comprehensive health examination program...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29686863/fat-soluble-vitamins-a-and-e-and-health-disparities-in-a-cohort-of-pregnant-women-at-delivery
#8
Corrine Hanson, Marina Verdi Schumacher, Elizabeth Lyden, Dejun Su, Jeremy Furtado, Rex Cammack, Bradley Bereitschaft, Matthew Van Ormer, Howard Needelman, Elizabeth McGinn, Katherine Rilett, Caleb Cave, Rebecca Johnson, Kara Weishaar, Ann Anderson-Berry
The objective of the present study was to evaluate intakes and serum levels of vitamin A, vitamin E, and related compounds in a cohort of maternal-infant pairs in the Midwestern USA in relation to measures of health disparities. Concentrations of carotenoids and tocopherols in maternal serum were measured using HPLC and measures of socio-economic status, including food security and food desert residence, were obtained in 180 mothers upon admission to a Midwestern Academic Medical Center labour and delivery unit...
2018: Journal of Nutritional Science
https://www.readbyqxmd.com/read/29674043/-1-h-nmr-and-antioxidant-profiles-of-polar-and-non-polar-extracts-of-persimmon-diospyros-kaki-l-metabolomics-study-based-on-cultivars-and-origins
#9
M Maulidiani, Ahmed Mediani, Faridah Abas, Yong Seo Park, Yang-Kyun Park, Young Mo Kim, Shela Gorinstein
Persimmon (Diospyros kaki L.) is one of the most important fruits that has been consumed for its medicinal properties due to the presence of some active metabolites, particularly polyphenols and carotenoids. Previously described methods, including HPLC, were limited in the determination of metabolites in different persimmon varieties. The present study shows the evaluation and the differences among persimmon polar and non-polar extracts by 1 H NMR-based metabolomics approach. The hierarchical clustering analysis (HCA) based on score values of principal component analysis (PCA) model was used to analyze the important compounds in investigated fruits...
July 1, 2018: Talanta
https://www.readbyqxmd.com/read/29666539/oxidative-status-of-a-yogurt-like-fermented-maize-product-containing-phytosterols
#10
Adriana María Descalzo, Sergio Aníbal Rizzo, Adrien Servent, Luciana Rossetti, Marc Lebrun, Carolina Daiana Pérez, Renaud Boulanger, Christian Mestres, Dominique Pallet, Claudie Dhuique-Mayer
This work describes the formulation of a functional yogurt-like product based on fermented maize with added phytosterols and its oxidative stability during cold storage. The technological challenge was to stabilize 3.5% esterified phytosterols (between 2 and 3 g of free sterols) in a low-fat emulsion and to preserve the obtained product throughout processing and storage. The natural bioactive compounds: lutein, zeaxanthin, β-cryptoxanthin, β-carotene and γ-tocopherol were detected in the yogurt, and remained stable during 12 days of refrigeration...
May 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29605494/plasma-proteins-associated-with-circulating-carotenoids-in-nepalese-school-aged-children
#11
Abdulkerim Eroglu, Kerry J Schulze, James Yager, Robert N Cole, Parul Christian, Bareng A S Nonyane, Sun Eun Lee, Lee Shu Fune Wu, Subarna Khatry, John Groopman, Keith P West
Carotenoids are naturally occurring pigments that function as vitamin A precursors, antioxidants, anti-inflammatory agents or biomarkers of recent vegetable and fruit intake, and are thus important for population health and nutritional assessment. An assay approach that measures proteins could be more technologically feasible than chromatography, thus enabling more frequent carotenoid status assessment. We explored associations between proteomic biomarkers and concentrations of 6 common dietary carotenoids (α-carotene, β-carotene, lutein/zeaxanthin, β-cryptoxanthin, and lycopene) in plasma from 500 6-8 year old Nepalese children...
March 29, 2018: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/29605302/higher-dietary-carotenoid-intake-associated-with-lower-risk-of-hip-fracture-in-middle-aged-and-elderly-chinese-a-matched-case-control-study
#12
Wen-Ting Cao, Fang-Fang Zeng, Bao-Lin Li, Jie-Sheng Lin, Ya-Yong Liang, Yu-Ming Chen
BACKGROUND: Mechanism studies have suggested that carotenoids may benefit bone health due to their antioxidant properties, but epidemiological data on their effects on risk of hip fracture are sparse. PURPOSE: To explore the relationships between dietary total and specific carotenoids and the risk of hip fracture in a middle-aged and elderly Chinese population. DESIGN: A case-control study of 1070 patients with hip fractures (diagnosed within 2 weeks) aged 55-80 years and 1070 age- (within 3 years) and gender-matched controls was conducted in Guangdong, China between 2009 and 2015...
March 29, 2018: Bone
https://www.readbyqxmd.com/read/29594435/higher-serum-carotenoids-associated-with-improvement-of-non-alcoholic-fatty-liver-disease-in-adults-a-prospective-study
#13
Mian-Li Xiao, Geng-Dong Chen, Fang-Fang Zeng, Rui Qiu, Wen-Qi Shi, Jie-Sheng Lin, Yi Cao, Hua-Bin Li, Wen-Hua Ling, Yu-Ming Chen
PURPOSE: Previous studies have suggested that serum carotenoids might be inversely associated with non-alcoholic fatty liver disease (NAFLD), but little data came from longitudinal studies. We prospectively examined the associations between serum-carotenoid levels and NAFLD severity and the intermediary effects of retinol-binding protein 4 (RBP4), HOMA insulin-resistance index (HOMA-IR), body mass index (BMI), and serum triglycerides in middle-aged and elderly Chinese adults. METHODS: This prospective study included 3336 Chinese adults (40-75 years)...
March 29, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29566784/antioxidant-cryptoxanthin-enhances-porcine-oocyte-maturation-and-subsequent-embryo-development-in-vitro
#14
Yun-Gwi Park, Seung-Eun Lee, Yeo-Jin Son, Sang-Gi Jeong, Min-Young Shin, Won-Jae Kim, Eun-Young Kim, Se-Pill Park
Oxidative stress is partly responsible for the poor quality of IVM oocytes. The present study investigated the effects of the antioxidant β-cryptoxanthin on the IVM of porcine oocytes and the in vitro development of the ensuing embryos. Oocytes were matured in IVM medium containing different concentrations of β-cryptoxanthin (0, 0.1, 1, 10 or 100μM). Treatment with 1µM β-cryptoxanthin (Group 1B) improved polar body extrusion and the expression of maturation-related genes in cumulus cells and oocytes compared with control...
March 23, 2018: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/29551944/medically-important-carotenoids-from-momordica-charantia-and-their-gene-expressions-in-different-organs
#15
Do Manh Cuong, Mariadhas Valan Arasu, Jin Jeon, Yun Ji Park, Soon-Jae Kwon, Naif Abdullah Al-Dhabi, Sang Un Park
Carotenoids, found in the fruit and different organs of bitter melon ( Momordica charantia ), have attracted great attention for their potential health benefits in treating several major chronic diseases. Therefore, study related to the identification and quantification of the medically important carotenoid metabolites is highly important for the treatment of various disorderes. The present study involved in the identification and quantification of the various carotenoids present in the different organs of M...
December 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/29534543/validation-of-a-dietary-screening-tool-in-a-middle-aged-appalachian-population
#16
Melissa Ventura Marra, Sowmyanarayanan V Thuppal, Elizabeth J Johnson, Regan L Bailey
Proactive nutrition screening is an effective public health strategy for identifying and targeting individuals who could benefit from making dietary improvements for primary and secondary prevention of disease. The Dietary Screening Tool (DST) was developed and validated to assess nutritional risk among rural older adults. The purpose of this study was to evaluate the utility and validity of the DST to identify nutritional risk in middle-aged adults. This cross-sectional study in middle-aged adults (45-64 year olds, n = 87) who reside in Appalachia, examined nutritional status using an online health survey, biochemical measures, anthropometry, and three representative 24-h dietary recalls...
March 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29508696/higher-dietary-and-serum-carotenoid-levels-are-associated-with-lower-carotid-intima-media-thickness-in-middle-aged-and-elderly-people
#17
Cheng Wang, Rui Qiu, Yi Cao, Wei-Fu Ouyang, Hua-Bin Li, Wen-Hua Ling, Yu-Ming Chen
Several studies have suggested that higher carotenoid levels may be beneficial for atherosclerosis patients, but few studies have examined this relationship in the Chinese population. This cross-sectional study examined the association between the levels of carotenoids in diet and serum and carotid intima-media thickness (IMT) in Chinese adults aged 50-75 years in Guangzhou, China. Dietary intake was assessed using a FFQ. HPLC was used to assay the serum concentrations of α-carotene, β-carotene, lutein+zeaxanthin, β-cryptoxanthin and lycopene...
March 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29439339/plasma-antioxidant-status-in-patients-with-alzheimer-s-disease-and-cognitively-intact-elderly-a-meta-analysis-of-case-control-studies
#18
Kathryn Mullan, Chris R Cardwell, Bernadette McGuinness, Jayne V Woodside, Gareth J McKay
Serum antioxidants may afford neuroprotection against Alzheimer's disease (AD) via correction of the pro-oxidative imbalance but findings reported have been inconsistent. We compared the pooled mean difference in serum levels of ten dietary antioxidants between patients with AD and cognitively intact controls from 52 studies in meta-analyses using random-effects models. Patients with AD had significantly lower plasma levels of α-carotene, β-carotene, lycopene, lutein, vitamin A, C, and E, and uric acid. No significant difference was observed for plasma levels of β-cryptoxanthin and zeaxanthin...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29401293/fruit-and-vegetable-consumption-and-risk-of-endometriosis
#19
H R Harris, A C Eke, J E Chavarro, S A Missmer
STUDY QUESTION: Is there an association between intake of fruits and vegetables and risk of laparoscopically confirmed endometriosis? SUMMARY ANSWER: Higher intake of fruits, particularly citrus fruits, is associated with a lower risk of endometriosis. WHAT IS KNOWN ALREADY: Two case-control studies have examined the associations between fruit and vegetable intake and endometriosis risk with contrasting results. Diets rich in fruits and vegetables include higher levels of pro-vitamin A nutrients (alpha-carotene, beta-carotene, beta-cryptoxanthin) and women with endometriosis have been reported to have lower intake of vitamin A than women without endometriosis...
April 1, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29384387/racial-differences-in-dietary-antioxidant-intake-and-cardiac-event-free-survival-in-patients-with-heart-failure
#20
Jia-Rong Wu, Eun Kyeung Song, Debra K Moser, Terry A Lennie
BACKGROUND: Heart failure is a chronic, burdensome condition with higher re-hospitalization rates in African Americans than Whites. Higher dietary antioxidant intake is associated with lower oxidative stress and improved endothelial function. Lower dietary antioxidant intake in African Americans may play a role in the re-hospitalization disparity between African American and White patients with heart failure. OBJECTIVE: The objective of this study was to examine the associations among race, dietary antioxidant intake, and cardiac event-free survival in patients with heart failure...
April 2018: European Journal of Cardiovascular Nursing
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