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https://www.readbyqxmd.com/read/29345907/effects-of-plant-sterols-and-or-%C3%AE-cryptoxanthin-at-physiological-serum-concentrations-on-suicidal-erythrocyte-death
#1
Andrea Alvarez-Sala, Gabriel López-García, Alessandro Attanzio, Luisa Tesoriere, Antonio Cilla, Reyes Barbera, Amparo Alegria
The eryptotic and hemolytic effects of a phytosterol (PS) mixture (β-sitosterol, campesterol, stigmasterol) and/or β-cryptoxanthin (β-Cx) at physiological serum concentration and their effect against oxidative stress induced by tert-butylhydroperoxide (tBOOH) (75 and 300 µM) were evaluated. β-Cryptoxanthin produced an increase in eryptotic cells, cell volume, hemolysis and glutathione depletion (GSH), without ROS overproduction and intracellular Ca2+ influx. Co-incubation of both bioactive compounds protected against β-Cx-induced eryptosis...
January 18, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29338336/changes-in-microbial-growth-carotenoids-and-water-soluble-tannin-content-of-ripe-persimmon-beverage-after-ultra-high-pressure-treatment
#2
Gi-Chang Kim, Sang-Bum Kim, Jin-Sook Kim, Kyung-Mi Kim, Song-Yi Choi
To avoid the loss of carotenoids and increasing the tannin content associated with pasteurization, we tested ultra-high pressure treatment of ripe persimmon beverage. We compared microbial counts (aerobic bacteria, coliforms, and mould), carotenoid contents, and water-soluble tannin contents between heat- and ultra-high pressure-treated beverages. No microbial contamination was detected after pasteurization or ultra-high pressure treatment at 400 MPa for more than 5 min. Ultra-high pressure treatment significantly prevented the reduction in carotenoids (lutein, zeaxanthin, β-cryptoxanthin, β-carotene, lycopene), with losses of 3...
January 1, 2018: Food Science and Technology International, Ciencia y Tecnología de Los Alimentos Internacional
https://www.readbyqxmd.com/read/29334323/development-of-functional-agricultural-products-utilizing-the-new-health-claim-labeling-system-in-japan
#3
Mari Maeda-Yamamoto, Toshio Ohtani
In April 2015, Consumer Affairs Agency of Japan launched a new food labeling system known as "Foods with Function Claims (FFC)." Under this system, the food industry independently evaluates scientific evidence on foods and describes their functional properties. As of May 23, 2017, 1023 FFC containing 8 fresh foods have been launched. Meanwhile, to clarify the health-promoting effects of agricultural products, National Agriculture and Food Research Organization (NARO) implemented the "Research Project on Development of Agricultural Products" and demonstrated the risk reduction of osteoporosis of β-cryptoxanthin rich Satsuma mandarins and the anti-allergic effect of the O-methylated catechin rich tea cultivar Benifuuki...
January 15, 2018: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/29324670/dietary-carotenoid-intakes-and-prostate-cancer-risk-a-case-control-study-from-vietnam
#4
Dong Van Hoang, Ngoc Minh Pham, Andy H Lee, Duong Nhu Tran, Colin W Binns
The incidence of prostate cancer has increased in Vietnam, but there have been few studies of the risk factors associated with this change. This retrospective case-control study investigated the relation of the intake of carotenoids and their food sources to prostate cancer risk. A sample of 652 participants (244 incident prostate cancer patients, aged 64-75 years, and 408 age frequency-matched controls) were recruited in Ho Chi Minh City during 2013-2015. The habitual diet was ascertained with a validated food-frequency questionnaire, and other factors including demographic and lifestyle characteristics were assessed via face-to-face interviews by trained nurses...
January 11, 2018: Nutrients
https://www.readbyqxmd.com/read/29321687/impact-of-biofortified-maize-consumption-on-serum-carotenoid-concentrations-in-zambian-children
#5
Amanda C Palmer, Neal E Craft, Kerry J Schulze, Maxwell Barffour, Justin Chileshe, Ward Siamusantu, Keith P West
Biofortified maize, designed as an intervention strategy to prevent vitamin A deficiency, can provide upwards of 15 μg β-carotene per g dry weight. Some varieties also have elevated concentrations of other carotenoids. We conducted a cluster randomized, controlled feeding trial in rural Zambia to test the impact of daily consumption of biofortified maize over a 6-month period on vitamin A status. Serum concentrations of retinol and carotenoids were assessed by high-performance liquid chromatography. Data on circulating carotenoids by intervention group in 679 children are reported here...
January 10, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29249178/biomarkers-of-cardiometabolic-health-and-nutritional-status-in-individuals-with-positive-celiac-disease-serology
#6
Joseph Jamnik, David Ja Jenkins, Ahmed El-Sohemy
BACKGROUND: Celiac disease (CD) is an autoimmune disorder characterized by damage to the intestinal mucosa and nutrient malabsorption in severe cases. However, it remains unclear whether nutrient deficiencies and other adverse health effects are prevalent in individuals with positive CD serology identified through screening studies. OBJECTIVE: The objective was to determine whether biomarkers of cardiometabolic health and nutritional status differ between those with positive and negative CD serology identified in a screening study of Canadian adults...
January 1, 2017: Nutrition and Health
https://www.readbyqxmd.com/read/29230830/in-vitro-bioaccessibility-of-individual-carotenoids-from-persimmon-diospyros-kaki-cv-rojo-brillante-used-as-an-ingredient-in-a-model-dairy-food
#7
Tomás García-Cayuela, Beatriz Nuño Escobar, Jorge Welti-Chanes, M Pilar Cano
BACKGROUND: Addition of persimmon fruit, which is highly rich in carotenoids, to dairy products represents an alternative to obtain functional foods. However, carotenoid bioaccessibility is strongly influenced by fat content and food composition. That is why in vitro bioaccessibility of individual carotenoids was evaluated in persimmon-based dairy products formulated with whole (3.6 % fat) or skimmed milk (0.25% fat) and different freeze-dried persimmon tissues. RESULTS: Unambiguous identification of 7 xanthophylls (neoxanthin, violaxanthin, antheraxanthin, lutein, zeaxanthin, lutein epoxide and β-cryptoxanthin) and 3 hydrocarbon carotenes (α-carotene, β-carotene and lycopene) was achieved using high perfomance liquid chromatography with a reverse phase C-30...
December 11, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29215107/%C3%AE-carotene-bioaccessibility-from-biofortified-maize-zea-mays-is-related-to-its-density-and-is-negatively-influenced-by-lutein-and-zeaxanthin
#8
Nivedita Dube, Purna Chandra Mashurabad, Firoz Hossain, Raghu Pullakhandam, Longvah Thingnganing, Dinesh Kumar Bharatraj
Biofortification of maize with provitamin A (pro-VA) carotenoids has been successful, but the bioavailability of carotenoids needs to be explored. In the present study, we investigated the carotenoid content, micellarization and intestinal cell uptake of carotenoids from 10 maize hybrids [normal maize, quality protein maize (QPM), pro-VA carotenoid and double biofortified QPM + pro-VA maize hybrids] using a simulated in vitro digestion/Caco-2 cell model. The pro-VA carotenoid content of biofortified maize hybrids is 2-10 fold higher compared to that of normal maize...
December 7, 2017: Food & Function
https://www.readbyqxmd.com/read/29207502/relationship-between-vitamin-intake-and-depressive-symptoms-in-elderly-japanese-individuals-differences-with-gender-and-body-mass-index
#9
Thao Thi Thu Nguyen, Hiromasa Tsujiguchi, Yasuhiro Kambayashi, Akinori Hara, Sakae Miyagi, Yohei Yamada, Haruki Nakamura, Yukari Shimizu, Daisuke Hori, Fumihiko Suzuki, Koichiro Hayashi, Hiroyuki Nakamura
Only a few studies have focused on the relationship between vitamin intake and depressive symptoms in Japanese individuals. This cross-sectional study investigated the relationship between vitamin intake and depressive symptoms in 1634 elderly Japanese individuals (65 years and older). The consumption of fifteen vitamins including retinol, a retinol equivalent, beta-carotene equivalent, vitamin D, alpha-tocopherol, vitamin K, vitamin group B, vitamin C, and cryptoxanthine was analyzed using a brief-type self-administered diet history questionnaire (BDHQ)...
December 3, 2017: Nutrients
https://www.readbyqxmd.com/read/29131551/%C3%AE-cryptoxanthin-inhibits-angiogenesis-in-human-umbilical-vein-endothelial-cells-huvec-through-retinoic-acid-receptor-rar
#10
José Manuel Quesada-Gómez, Raquel Santiago-Mora, Mario Durán-Prado, Gabriel Dorado, Gema Pereira-Caro, José Manuel Moreno-Rojas, Antonio Casado-Díaz
SCOPE: β-Cryptoxanthin is an abundant carotenoid in fruits and vegetables that can be quantified in human blood-serum. Yet, contrary to other carotenoids, its effects on endothelial cells and angiogenesis remain unknown. METHODS AND RESULTS: Human umbilical-vein endothelial cells (HUVEC) were treated with 0.01, 0.1 or 1 μM of β-cryptoxanthin. Antioxidant activity was determined by its free radical scavenging and oxygen-radical absorbance capacity (ABTS and ORAC assays)...
November 13, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/29120377/concentrations-of-carotenoids-and-tocopherols-in-breast-milk-from-urban-chinese-mothers-and-their-associations-with-maternal-characteristics-a-cross-sectional-study
#11
Yong Xue, Esther Campos-Giménez, Karine Meisser Redeuil, Antoine Lévèques, Lucas Actis-Goretta, Gerard Vinyes-Pares, Yumei Zhang, Peiyu Wang, Sagar K Thakkar
Milk composition remains the best estimate of infant requirements. The aims of this study were to quantify carotenoids and tocopherols in human milk from healthy Chinese mothers, and to explore their associations with lactation stage, region, socio-economic and obstetric characteristics, and dietary intake. Human milk was obtained from 509 healthy mothers, and concentrations of carotenoids and tocopherols were analyzed by Ultra High Performance Liquid Chromatography. The mothers' socio-economic and obstetric characteristics and dietary intake through a single 24-h dietary recall were evaluated...
November 9, 2017: Nutrients
https://www.readbyqxmd.com/read/29110607/serum-carotenoids-and-risks-of-diabetes-and-diabetic-retinopathy-in-a-chinese-population-sample
#12
C She, F Shang, K Zhou, N Liu
OBJECTIVE: Diabetes mellitus (DM) and diabetic retinopathy (DR) are associated with oxidative stress and carotenoids have antioxidant properties. This study aimed to test the relationship between serum carotenoid concentrations and the risk for DM and DR. METHODS: This is a cross-sectional study of the Chinese urban population. A total of 747 subjects, consisting of 272 DR patients, 190 diabetic patients without retinopathy, and 285 non-diabetes mellitus healthy controls, were recruited to this study...
November 5, 2017: Current Molecular Medicine
https://www.readbyqxmd.com/read/29106966/single-step-preparation-of-selected-biological-fluids-for-the-high-performance-liquid-chromatographic-analysis-of-fat-soluble-vitamins-and-antioxidants
#13
Giacomo Lazzarino, Salvatore Longo, Angela Maria Amorini, Valentina Di Pietro, Serafina D'Urso, Giuseppe Lazzarino, Antonio Belli, Barbara Tavazzi
Fat-soluble vitamins and antioxidants are of relevance in health and disease. Current methods to extract these compounds from biological fluids mainly need use of multi-steps and multi organic solvents. They are time-consuming and difficult to apply to treat simultaneously large sample number. We here describe a single-step, one solvent extraction of fat-soluble vitamins and antioxidants from biological fluids, and the chromatographic separation of all-trans-retinoic acid, 25-hydroxycholecalciferol, all-trans-retinol, astaxanthin, lutein, zeaxanthin, trans-β-apo-8'-carotenal, γ-tocopherol, β-cryptoxanthin, α-tocopherol, phylloquinone, lycopene, α-carotene, β-carotene and coenzyme Q10...
December 8, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28972218/impact-of-in-vitro-digestion-phases-on-the-stability-and-bioaccessibility-of-carotenoids-and-their-esters-in-mandarin-pulps
#14
Fabiane Cristina Petry, Adriana Zerlotti Mercadante
The composition of carotenoids (carotenes and free and acylated xanthophylls) and their bioaccessibilities were determined for the first time in pulps of mandarins cultivated in Brazil. Two cultivars of mandarin, Citrus reticulata Blanco cv. 'Ponkan' and Citrus reticulata × C. sinensis cv. 'Murcott', showed higher contents of most carotenoids compared to those found in C. deliciosa Tenore cv. 'Rio'. The major carotenoids in mandarin cv. 'Ponkan' and 'Murcott' were (all-E)-β-cryptoxanthin laurate (19-21%), (all-E)-β-cryptoxanthin myristate (15-17%) and (Z)-ζ-carotene (7-12%), followed by (all-E)-β-cryptoxanthin palmitate (4-7%), free (all-E)-β-cryptoxanthin (5-6%) and (all-E)-β-carotene (4-5%), while in mandarin cv...
October 3, 2017: Food & Function
https://www.readbyqxmd.com/read/28942446/status-of-vitamin-a-and-related-compounds-and-clinical-outcomes-in-maternal-infant-pairs-in-the-midwestern-united-states
#15
Corrine Hanson, Marina Schumacher, Elizabeth Lyden, Jeremy Furtado, Matthew Van Ormer, Elizabeth McGinn, Katherine Rilett, Caleb Cave, Rebecca Johnson, Kara Weishaar, Ann Anderson-Berry
BACKGROUND: Vitamin A is an essential nutrient for pregnant women, and other vitamin A-related compounds, including lutein and lycopene, have been associated with maternal-infant outcomes. The objective of this study was to quantify the status of vitamin A and related compounds in maternal-infant pairs at the time of delivery, and to determine its impact on clinical outcomes. METHODS: Maternal and cord blood samples were collected in 189 mother-infant pairs. Concentrations of lutein + zeaxanthin, β-cryptoxanthin, lycopene, carotenes, and retinol were measured using high-performance liquid chromatography...
September 22, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28926945/association-between-dietary-carotenoid-intake-and-bone-mineral-density-in-korean-adults-aged-30-75-years-using-data-from-the-fourth-and-fifth-korean-national-health-and-nutrition-examination-surveys-2008-2011
#16
Gebereamanuel Meron Regu, Hyesook Kim, You Jin Kim, Ju Eun Paek, Gunjeong Lee, Namsoo Chang, Oran Kwon
Age-related bone loss is a major public health problem. This cross-sectional study examined the association between the dietary intake of carotenoids and bone mineral density (BMD). Data from 8022 subjects (3763 males and 4259 females) aged 30-75 years included in the Korean National Health and Nutrition Examination Survey (2008-2011) were analyzed. BMD was measured by dual-energy X-ray absorptiometry. Intake of carotenoids was estimated using 24-h dietary recall. In multiple linear analysis, after adjusting for covariates, lutein + zeaxanthin and β-cryptoxanthin intake was positively associated with total hip BMD in males and premenopausal women respectively, while β-carotene intake was positively correlated with femoral neck, total hip, and whole-body BMD in postmenopausal women...
September 16, 2017: Nutrients
https://www.readbyqxmd.com/read/28895235/infrared-assisted-extraction-and-hplc-analysis-of-prunus-armeniaca-l-pomace-and-detoxified-kernel-and-their-antidiabetic-effects
#17
Karim Raafat, Nada El-Darra, Fatima A Saleh, Hiba N Rajha, Richard G Maroun, Nicolas Louka
INTRODUCTION: Prunus armeniaca L. (P. armeniaca) is one of the medicinal plants with a high safety-profile. OBJECTIVES: The aim of this work was to make an infrared-assisted extraction (IR-AE) of P. armeniaca fruit (pomace) and kernel, and analyse them using reverse phase high-performance liquid chromatography (RP-HPLC) aided method. METHODS: IR-AE is a novel-technique aimed at increasing the extraction-efficiency. The antidiabetic-potentials of the P...
September 12, 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/28888458/the-high-content-of-%C3%AE-carotene-present-in-orange-pulp-fruits-of-carica-papaya-l-is-not-correlated-with-a-high-expression-of-the-cplcy-%C3%AE-2-gene
#18
Arianna C Chan-León, Humberto Estrella-Maldonado, Pascal Dubé, Gabriela Fuentes Ortiz, Francisco Espadas-Gil, Carlos Talavera May, Jorge Ramírez Prado, Yves Desjardins, Jorge M Santamaría
We investigated the transcriptional regulation of six genes involved in carotenoid biosynthesis, together with the carotenoid accumulation during postharvest ripening of three different papaya genotypes of contrasting pulp color. Red-pulp genotype (RPG) showed the lowest content of yellow pigments (YP), such as β-cryptoxanthin, zeaxanthin, and violaxanthin, together with the lowest relative expression levels (REL) of CpLCY-β2 and CpCHX-β genes. On the contrary, the yellow-pulp genotype (YPG) showed the highest content of YP and the highest REL of CpLCY-β2 and CpCHX-β genes...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28873580/thermal-degradation-kinetics-of-all-trans-and-cis-carotenoids-in-a-light-induced-model-system
#19
Ya-Dong Xiao, Wu-Yang Huang, Da-Jing Li, Jiang-Feng Song, Chun-Quan Liu, Qiu-Yu Wei, Min Zhang, Qiu-Ming Yang
Thermal degradation kinetics of lutein, zeaxanthin, β-cryptoxanthin, β-carotene was studied at 25, 35, and 45°C in a model system. Qualitative and quantitative analyses of all-trans- and cis-carotenoids were conducted using HPLC-DAD-MS technologies. Kinetic and thermodynamic parameters were calculated by non-linear regression. A total of 29 geometrical isomers and four oxidation products were detected, including all-trans-, keto compounds, mono-cis- and di-cis-isomers. Degradations of all-trans-lutein, zeaxanthin, β-cryptoxanthin, and β-carotene were described by a first-order kinetic model, with the order of rate constants as kβ-carotene>kβ-cryptoxanthin>klutein>kzeaxanthin...
January 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28836851/provitamin-a-biofortified-maize-consumption-increases-serum-xanthophylls-and-13-c-natural-abundance-of-retinol-in-zambian-children
#20
RANDOMIZED CONTROLLED TRIAL
Jesse Sheftel, Bryan M Gannon, Christopher R Davis, Sherry A Tanumihardjo
Plants that undergo C4 photosynthesis, such as maize, are enriched in the stable isotope of carbon ((13)C) compared with other dietary plants and foods. Consumption of maize that has been biofortified to contain elevated levels of provitamin A carotenoids (orange maize) increased the abundance of (13)C in serum retinol of Mongolian gerbils. We evaluated this method in humans to determine if it has potential for further use in intervention effectiveness studies. A random subset of samples from a two-month randomized controlled feeding trial of rural three- to five-year old Zambian children were used to determine the impact of orange maize intake on serum carotenoid concentrations ( n = 88) and (13)C-natural abundance in serum retinol ( n = 77)...
September 2017: Experimental Biology and Medicine
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