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https://www.readbyqxmd.com/read/27913933/fatigue-reduction-diet-in-breast-cancer-survivors-a-pilot-randomized-clinical-trial
#1
Suzanna Maria Zick, Justin Colacino, Maria Cornellier, Tohfa Khabir, Katie Surnow, Zora Djuric
PURPOSE: Fatigue is a prevalent and burdensome effect of breast cancer. Fatigue has been linked to chronic inflammation, and diets high in antioxidant nutrients have been associated with lesser prevalence and severity of fatigue. Studies are needed, however, to test if antioxidant-rich diets could improve fatigue. METHODS: Pilot, randomized, trial conducted between January 2014 and April 2015, to investigate if a 3-month diet rich in fruit, vegetables, whole grains, and omega-3 fatty acid-rich foods, named the fatigue reduction diet (FRD), improved fatigue and sleep compared to an attention control, named the general health curriculum (GHC)...
December 2, 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27903840/evaluation-of-antioxidant-intakes-in-relation-to-inflammatory-markers-expression-within-the-normal-breast-tissue-of-breast-cancer-patients
#2
Danielle Larouche, Mirette Hanna, Sue-Ling Chang, Simon Jacob, Bernard Têtu, Caroline Diorio
Chronic inflammation may be a causative factor in breast cancer. One possible underlying mechanism is the generation of oxidative stress, which may favor tumorigenic processes. Antioxidant consumption may, therefore, help reduce tissue inflammation levels. However, few studies have explored this relation in breast tissue. We aimed to evaluate correlations between antioxidant (vitamin A/retinol, vitamin C, vitamin E, β-carotene, α-carotene, lycopene, lutein/zeaxanthin, β-cryptoxanthin, selenium, and zinc) intakes and protein expression levels of interleukin (IL)-6, tumor necrosis factor-α, C-reactive protein, cyclooxygenase-2, leptin, serum amyloid A1, signal transducer and activator of transcription 3, IL-8, IL-10, lactoferrin, and transforming growth factor-β measured in the normal breast tissue of 160 women diagnosed with breast cancer...
November 30, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/27899047/phytochemicals-and-antioxidant-capacity-in-four-italian-traditional-maize-zea-mays-l-varieties
#3
Antonella Capocchi, Stefania Bottega, Carmelina Spanò, Debora Fontanini
Flours of four pigmented (from orange to red and dark red) local Italian corns, studied for their soluble, soluble conjugate, and insoluble-bound phenols and flavonoids, showed a prevalence of the insoluble-bound fraction (70-80%). Correlations were found between the flours antioxidant capacity, measured with CUPRAC, FRAP, and DPPH methods, and soluble phenols and flavonoids content. A correlation was also found between ascorbic acid content and flours antioxidant power. Anthocyanins were present in small amounts in the red/dark red seeds; however, acid-alcohol assays and spectral analyses of pericarp extracts indicated the presence of red-brick phlobaphenes in these varieties...
November 29, 2016: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/27862386/no-detectable-carotenoid-concentrations-in-serum-of-llamas-and-alpacas
#4
J Raila, F J Schweigert, A Stanitznig, B Lambacher, S Franz, S Baldermann, T Wittek
Carotenoids are lipid-soluble pigments and important for a variety of physiological functions. They are major dietary vitamin A precursors and act as lipophilic antioxidants in a variety of tissues and are associated with important health benefits in humans and animals. All animals must acquire carotenoids from their diet, but to our knowledge, there are no studies investigating the intestinal carotenoid absorption and their blood concentrations in New World camelids. The present study aimed to assess the serum concentrations of selected carotenoids in llamas (n = 13) and alpacas (n = 27)...
November 9, 2016: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/27862054/determination-of-target-fat-soluble-micronutrients-in-rainbow-trout-s-muscle-and-liver-tissues-by-liquid-chromatography-with-diode-array-tandem-mass-spectrometry-detection
#5
Virginia Pérez Fernández, Salvatore Ventura, Pierpaolo Tomai, Roberta Curini, Alessandra Gentili
This paper describes an analytical approach, based on liquid chromatography-diode array detection-tandem mass spectrometry (LC-DAD-MS/MS), for characterizing the fat-soluble micronutrient fraction in rainbow trout (Oncorhynchus mykiss). Two different procedures were applied to isolate the analytes from liver and muscle tissue: overnight cold saponification to hydrolyze bound forms and to simplify the analysis; matrix solid phase dispersion (MSPD) to avoid artifacts and to maintain unaltered the naturally occurring forms...
November 12, 2016: Electrophoresis
https://www.readbyqxmd.com/read/27812831/carotenoids-phenolic-profile-mineral-content-and-antioxidant-properties-in-flesh-and-peel-of-prunus-persica-fruits-during-two-maturation-stages
#6
Samia Dabbou, Samira Maatallah, Antonella Castagna, Monia Guizani, Wala Sghaeir, Hichem Hajlaloui, Annamaria Ranieri
Carotenoids and phenolic profile, antioxidant activity as well as concentrations of selected macronutrients (K, N, Mg, Ca and Na) and micronutrients (Zn, Cu and Mn) in flesh and peel of peach fruit were recorded at two harvest dates. Predominant mineral was potassium, followed by calcium, magnesium and sodium. The concentration of most micronutrients was greater in the peel than in the flesh especially in early season. The concentration of most elements in flesh and peel decreased during fruit maturation. Total carotenoids content varied with respect to the cultivar...
November 3, 2016: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/27801820/a-comparison-of-nutritional-antioxidant-content-in-breast-milk-donor-milk-and-infant-formulas
#7
Corrine Hanson, Elizabeth Lyden, Jeremy Furtado, Matthew Van Ormer, Ann Anderson-Berry
Human milk is the optimal food for human infants, including infants born prematurely. In the event that a mother of a hospitalized infant cannot provide breast milk, donor milk is considered an acceptable alternative. It is known that the macronutrient composition of donor milk is different than human milk, with variable fat content and protein content. However, much less is known about the micronutrient content of donor milk, including nutritional antioxidants. Samples of breast milk from 12 mothers of infants hospitalized in the Newborn Intensive Care Unit until were collected and analyzed for concentrations of nutritional antioxidants, including α-carotene, β-carotene, β-cryptoxanthin, lycopene, lutein + zeaxanthin, retinol, and α-tocopherol...
October 28, 2016: Nutrients
https://www.readbyqxmd.com/read/27712060/composition-by-lc-ms-ms-of-new-carotenoid-esters-in-mango-and-citrus
#8
Fabiane Cristina Petry, Adriana Zerlotti Mercadante
Interest about composition of carotenoid esters of fruits is growing since esterification may affect their bioavailability. Thus, the aim was to provide detailed identification of carotenoid esters in Citrus and mango. Orange cv. Valencia and cv. Pera presented 9 free carotenoids, 38 mono- and 60 diesters. Violaxanthin and luteoxanthin derivatives were the major ones, followed by antheraxanthin, lutein, zeaxanthin, β-cryptoxanthin and zeinoxanthin esters; many of them reported for the first time in orange pulp...
October 7, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27706032/plasma-carotenoids-tocopherols-and-retinol-in-the-age-stratified-35-74-years-general-population-a-cross-sectional-study-in-six-european-countries
#9
Wolfgang Stuetz, Daniela Weber, Martijn E T Dollé, Eugène Jansen, Beatrix Grubeck-Loebenstein, Simone Fiegl, Olivier Toussaint, Juergen Bernhardt, Efstathios S Gonos, Claudio Franceschi, Ewa Sikora, María Moreno-Villanueva, Nicolle Breusing, Tilman Grune, Alexander Bürkle
Blood micronutrient status may change with age. We analyzed plasma carotenoids, α-/γ-tocopherol, and retinol and their associations with age, demographic characteristics, and dietary habits (assessed by a short food frequency questionnaire) in a cross-sectional study of 2118 women and men (age-stratified from 35 to 74 years) of the general population from six European countries. Higher age was associated with lower lycopene and α-/β-carotene and higher β-cryptoxanthin, lutein, zeaxanthin, α-/γ-tocopherol, and retinol levels...
September 30, 2016: Nutrients
https://www.readbyqxmd.com/read/27706028/lycopene-lutein-and-zeaxanthin-may-reduce-faecal-blood-mucus-and-pus-but-not-abdominal-pain-in-individuals-with-ulcerative-colitis
#10
Dominika Głąbska, Dominika Guzek, Paulina Zakrzewska, Dariusz Włodarek, Gustaw Lech
BACKGROUND: The main symptom of ulcerative colitis is diarrhoea, which is often accompanied by painful tenesmus and faecal blood and mucus. It sometimes co-occurs with abdominal pain, fever, feeling of fatigue, loss of appetite and weight loss. Some dietary factors have been indicated as important in the treatment of ulcerative colitis. The aim of the study was to analyse the association between retinoid intake (total vitamin A, retinol, β-carotene, α-carotene, β-cryptoxanthin, lycopene, lutein and zeaxanthin) and ulcerative colitis symptoms (abdominal pain, faecal blood, faecal mucus, faecal pus) in individuals with ulcerative colitis in remission...
September 30, 2016: Nutrients
https://www.readbyqxmd.com/read/27633975/validity-and-reliability-of-a-brief-self-reported-questionnaire-assessing-fruit-and-vegetable-consumption-among-pregnant-women
#11
Lydi-Anne Vézina-Im, Gaston Godin, Charles Couillard, Julie Perron, Simone Lemieux, Julie Robitaille
BACKGROUND: Short instruments measuring frequency of specific foods, such as fruit and vegetable (FV), are increasingly used in interventions. The objective of the study was to verify the validity and test-retest reliability of such an instrument among pregnant women. METHODS: Pregnant women from the region of Quebec City, Quebec, Canada, were recruited through e-mails sent to female students and employees of the local university from October 2014 to April 2015...
2016: BMC Public Health
https://www.readbyqxmd.com/read/27628580/modelling-the-growth-kinetics-of-kocuria-marina-dagii-as-a-function-of-single-and-binary-substrate-during-batch-production-of-%C3%AE-cryptoxanthin
#12
Ruchira Mitra, Surabhi Chaudhuri, Debjani Dutta
In the present investigation, growth kinetics of Kocuria marina DAGII during batch production of β-Cryptoxanthin (β-CRX) was studied by considering the effect of glucose and maltose as a single and binary substrate. The importance of mixed substrate over single substrate has been emphasised in the present study. Different mathematical models namely, the Logistic model for cell growth, the Logistic mass balance equation for substrate consumption and the Luedeking-Piret model for β-CRX production were successfully implemented...
September 15, 2016: Bioprocess and Biosystems Engineering
https://www.readbyqxmd.com/read/27623933/%C3%AE-cryptoxanthin-reduced-lung-tumor-multiplicity-and-inhibited-lung-cancer-cell-motility-by-downregulating-nicotinic-acetylcholine-receptor-%C3%AE-7-signaling
#13
Anita R Iskandar, Benchun Miao, Xinli Li, Kang-Quan Hu, Chun Liu, Xiang-Dong Wang
Despite the consistent association between a higher intake of the provitamin A carotenoid β-cryptoxanthin (BCX) and a lower risk of lung cancer among smokers, potential mechanisms supporting BCX as a chemopreventive agent are needed. We first examined the effects of BCX on 4-[methyl nitrosamino]-1-[3-pyridyl]-1-butanone (NNK)-induced lung tumorigenesis in A/J mice. BCX supplementation was given daily to the mice starting 2 weeks prior to the injection of NNK and continued 16 weeks after NNK injection. BCX supplementation resulted in a dose-dependent increase of BCX concentration in both serum and lungs of the mice without a significant alteration of vitamin A (retinol and retinyl palmitate) concentration...
November 2016: Cancer Prevention Research
https://www.readbyqxmd.com/read/27592828/possible-gender-difference-in-anti-stress-effect-of-%C3%AE-cryptoxanthin
#14
Keiko Unno, Shigenori Noda, Yohei Kawasaki, Kazuaki Iguchi, Hiroshi Yamada
Beta-cryptoxanthin [β-CRX, (3R)-β, β-caroten-3-ol] is a provitamin A and a potent antioxidant that is abundant in Satsuma mandarin orange (Citrus unshiu MARC.), which is the most popular fruit in Japan. The anti-stress effect of β-CRX on humans was evaluated in fifth-year university students during both routine daily life at the university and at pharmacy practice. The study design was a double-blind group comparison and participants (n=20; female 12, male 8) were randomly assigned to β-CRX-rich orange juice or placebo (β-CRX was removed from orange juice) groups...
2016: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/27591863/plasma-fat-soluble-vitamin-and-carotenoid-concentrations-after-plant-sterol-and-plant-stanol-consumption-a-meta-analysis-of-randomized-controlled-trials
#15
Sabine Baumgartner, Rouyanne T Ras, Elke A Trautwein, Ronald P Mensink, Jogchum Plat
PURPOSE: Plant sterols and stanols interfere with intestinal cholesterol absorption, and it has been questioned whether absorption and plasma concentrations of fat-soluble vitamins and carotenoids are also affected. We conducted a meta-analysis to assess the effects of plant sterol and stanol consumption on plasma fat-soluble vitamin and carotenoid concentrations. METHODS: Forty-one randomized controlled trials involving 3306 subjects were included. Weighted absolute and relative changes of non-standardized and total cholesterol (TC)-standardized values (expressed as summary estimates and 95 % CIs) were calculated for three fat-soluble vitamins (α- and γ-tocopherol, retinol and vitamin D) and six carotenoids (β-carotene, α-carotene, lycopene, lutein, zeaxanthin and β-cryptoxanthin) using a random effects model...
September 3, 2016: European Journal of Nutrition
https://www.readbyqxmd.com/read/27572625/carotenoids-as-biomarkers-of-fruit-and-vegetable-intake-in-men-and-women
#16
Charles Couillard, Simone Lemieux, Marie-Claude Vohl, Patrick Couture, Benoît Lamarche
High fruit and vegetable (FAV) intake is associated with a lower prevalence of chronic diseases. Identifying the ideal number of FAV servings needed to reduce chronic disease risk is, however, difficult because of biases inherent to common self-report dietary assessment tools. The aim of our study was to examine the associations between daily FAV intake and plasma carotenoid concentrations in men and women enrolled in a series of fully controlled dietary interventions. We compiled and analysed data from a group of 155 men and 109 women who participated in six fully controlled dietary interventions and compared post-intervention fasting plasma carotenoid (α-carotene, β-carotene, β-cryptoxanthin, lutein, lycopene, zeaxanthin) concentrations with regard to the daily FAV servings consumed by the participants...
October 2016: British Journal of Nutrition
https://www.readbyqxmd.com/read/27570271/bioactive-compounds-and-quality-parameters-of-natural-cloudy-lemon-juices
#17
Filiz Uçan, Erdal Ağçam, Asiye Akyildiz
In this study, bioactive compounds (phenolic and carotenoid) and some quality parameters (color, browning index and hydroxymethylfurfural (HMF)) of natural cloudy lemon juice, pasteurized (90 °C/15 s) and storage stability of concentrated lemon juice (-25 °C/180 days) were carried out. Fifteen phenolic compounds were determined in the lemon juice and the most abounded phenolic compounds were hesperidin, eriocitrin, chlorogenic acid and neoeriocitrin. In generally, phenolic compound concentrations of lemon juice samples increased after the pasteurization treatment...
March 2016: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/27529203/in-vitro-inhibition-of-human-udp-glucuronosyl-transferase-ugt-isoforms-by-astaxanthin-%C3%AE-cryptoxanthin-canthaxanthin-lutein-and-zeaxanthin-prediction-of-in-vivo-dietary-supplement-drug-interactions
#18
Yu Fen Zheng, Jee Sun Min, Doyun Kim, Jung Bae Park, Sung-Wook Choi, Eun Seong Lee, Kun Na, Soo Kyung Bae
Despite the widespread use of the five major xanthophylls astaxanthin, β-cryptoxanthin, canthaxanthin, lutein, and zeaxanthin as dietary supplements, there have been no studies regarding their inhibitory effects on hepatic UDP-glucuronosyltransferases (UGTs). Here, we evaluated the inhibitory potential of these xanthophylls on the seven major human hepatic UGTs (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, UGT2B7 and UGT2B15) in vitro by LC-MS/MS using specific marker reactions in human liver microsomes (except UGT2B15) or recombinant supersomes (UGT2B15)...
2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27485231/carotenoids-in-adipose-tissue-biology-and-obesity
#19
M Luisa Bonet, Jose A Canas, Joan Ribot, Andreu Palou
Cell, animal and human studies dealing with carotenoids and carotenoid derivatives as nutritional regulators of adipose tissue biology with implications for the etiology and management of obesity and obesity-related metabolic diseases are reviewed. Most studied carotenoids in this context are β-carotene, cryptoxanthin, astaxanthin and fucoxanthin, together with β-carotene-derived retinoids and some other apocarotenoids. Studies indicate an impact of these compounds on essential aspects of adipose tissue biology including the control of adipocyte differentiation (adipogenesis), adipocyte metabolism, oxidative stress and the production of adipose tissue-derived regulatory signals and inflammatory mediators...
2016: Sub-cellular Biochemistry
https://www.readbyqxmd.com/read/27465725/high-vitamin-c-intake-with-high-serum-%C3%AE-cryptoxanthin-associated-with-lower-risk-for-osteoporosis-in-post-menopausal-japanese-female-subjects-mikkabi-cohort-study
#20
Minoru Sugiura, Mieko Nakamura, Kazunori Ogawa, Yoshinori Ikoma, Masamichi Yano
Recent epidemiological studies show that antioxidant vitamins and carotenoids might be beneficial to the maintenance of bone health. Recently, we found that serum carotenoids were inversely associated with the risk of developing osteoporosis in post-menopausal Japanese female subjects. However, little is known about the vitamin alone and/or the combination of the vitamin and carotenoid with the risk of osteoporosis. The objective of this study was to investigate longitudinally whether antioxidant vitamins and their combination with carotenoids are associated with the risk of developing of osteoporosis...
2016: Journal of Nutritional Science and Vitaminology
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