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https://www.readbyqxmd.com/read/27618153/emu-oil-combined-with-lyprinol%C3%A2-reduces-small-intestinal-damage-in-a-rat-model-of-chemotherapy-induced-mucositis
#1
Suzanne Mashtoub, Lorrinne S Lampton, Georgina L Eden, Ker Y Cheah, Kerry A Lymn, Juliana E Bajic, Gordon S Howarth
Chemotherapy-induced mucositis is characterized by inflammation and ulcerating lesions lining the alimentary tract. Emu Oil and Lyprinol™ have independently demonstrated their therapeutic potential in intestinal inflammatory disorders, including mucositis. We investigated Emu Oil and Lyprinol™ in combination for their further potential to alleviate chemotherapy-induced mucositis in rats. Rats were gavaged with (1 ml) water, Olive Oil, Emu Oil + Olive Oil, Lyprinol™ + Olive Oil or Emu Oil + Lyprinol™ from Days 0 to 7, injected with saline (control) or 5-Fluorouracil (5-FU) on Day 5 and euthanized on Day 8...
October 2016: Nutrition and Cancer
https://www.readbyqxmd.com/read/27383819/visual-pigments-in-a-palaeognath-bird-the-emu-dromaius-novaehollandiae-implications-for-spectral-sensitivity-and-the-origin-of-ultraviolet-vision
#2
Nathan S Hart, Jessica K Mountford, Wayne I L Davies, Shaun P Collin, David M Hunt
A comprehensive description of the spectral characteristics of retinal photoreceptors in palaeognaths is lacking. Moreover, controversy exists with respect to the spectral sensitivity of the short-wavelength-sensitive-1 (SWS1) opsin-based visual pigment expressed in one type of single cone: previous microspectrophotometric (MSP) measurements in the ostrich (Struthio camelus) suggested a violet-sensitive (VS) SWS1 pigment, but all palaeognath SWS1 opsin sequences obtained to date (including the ostrich) imply that the visual pigment is ultraviolet-sensitive (UVS)...
July 13, 2016: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/27191775/in-situ-dispersion-of-non-aqueous-fe3o4-nanocolloids-by-microdroplet-coalescence-and-their-use-in-the-preparation-of-magnetic-composite-particles
#3
Le Du, Yujun Wang, Jianhong Xu, Chun Shen, Guangsheng Luo
Monodispersity and size uniformity are critical issues for nanoparticles, especially for the inorganic particles dispersed in organic carriers serving as the precursor of composites. Herein, for the first time, we have developed a method based on flow-induced droplet coalescence for in situ dispersion of surface-modified Fe3O4 nanoparticles to prepare Fe3O4/polystyrene (Fe3O4/PS) composite particles. A plate-type microchannel was constructed to initiate droplet coalescence for reducing the water-oil interfacial area and for dispersing Fe3O4 nanoparticles into the precursor suspensions...
June 21, 2016: Soft Matter
https://www.readbyqxmd.com/read/27178879/amelioration-of-fca-induced-arthritis-on-topical-application-of-curcumin-in-combination-with-emu-oil
#4
Manish Kumar Jeengar, Shweta Shrivastava, S Chandra Mouli Veeravalli, V G M Naidu, Ramakrishna Sistla
OBJECTIVE: The aim of the present study was to investigate the skin penetration potential of emu oil and the possibility of enhancing the antiarthritic potential of lipophilic bioactive curcumin, which has poor permeability through biological membranes. METHODS: Solubility and ex vivo skin permeation studies were performed with water, corn oil, and emu oil as a vehicle using curcumin as a model drug. Carrageenan induced inflammation and Freund's complete adjuvant-induced arthritic rat models were used to evaluate enhanced antiinflammatory and antiarthritic effect of curcumin in combination of emu oil via topical route...
September 2016: Nutrition
https://www.readbyqxmd.com/read/27109049/emu-oil-based-nano-emulgel-for-topical-delivery-of-curcumin
#5
Manish Kumar Jeengar, Sri Vishnu Kiran Rompicharla, Shweta Shrivastava, Naveen Chella, Nalini R Shastri, V G M Naidu, Ramakrishna Sistla
Curcumin and emu oil derived from emu bird (Dromaius novaehollandiae) has shown promising results against inflammation. However, the delivery of curcumin is hindered due to low solubility and poor permeation. In addition, till date the role of emu oil in drug delivery has not been explored systemically. Hence, the current investigation was designed to evaluate the anti-inflammatory potential of curcumin in combination with emu oil from a nanoemulgel formulation in experimental inflammation and arthritic in vivo models...
June 15, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27069472/effects-of-topical-emu-oil-on-burn-wounds-in-the-skin-of-balb-c-mice
#6
Mohammad Afshar, Reza Ghaderi, Mahmoud Zardast, Parvin Delshad
The goal of this study was to determine the effect of topical Emu oil on the healing of burn wounds and hair follicle restoration in superficial II-degree burns in the skin of Balb/c mice. Thirty-two male Balb/c mice with burns on the back of the neck were divided into two groups: The Emu oil group received topical Emu oil twice daily, whereas the control was left untreated. Skin biopsies were obtained on days 4, 7, 10, and 14 of the experiment. Then the specimens were viewed with Olympus SZX research microscope...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/26852336/emu-oil-offers-protection-in-crohn-s-disease-model-in-rats
#7
Bhaskar Vemu, S Selvasubramanian, V Pandiyan
BACKGROUND: Emu oil is a product of animal origin used for the treatment of inflammation, burns etc. as a part of aboriginal medicine in Australia. Crohn's disease is a common inflammatory manifestation in humans and other animal species relating to the ulceration and digestive disturbances in upper gastro-intestinal tract. Aloe vera is commonly used substance from plant sources for inflammation, wound healing and various other properties. Given the difference in the source of the substances all the while playing a similar therapeutic role in different parts of the world, the present investigation was undertaken to evaluate the protective effect of aloe vera and emu oil alone and in combination; in comparison to sulfasalazine (Allopathic drug) as an alternative for the treatment of Crohn's disease...
2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/26217022/ratite-oils-promote-keratinocyte-cell-growth-and-inhibit-leukocyte-activation
#8
Darin C Bennett, Gigi Leung, Eddy Wang, Sam Ma, Blanche K K Lo, Kevin J McElwee, Kimberly M Cheng
Traditionally, native Australian aborigines have used emu oil for the treatment of inflammation and to accelerate wound healing. Studies on mice suggest that topically applied emu oil may have anti-inflammatory properties and may promote wound healing. We investigated the effects of ratite oils (6 emu, 3 ostrich, 1 rhea) on immortalized human keratinocytes (HaCaT cells) in vitro by culturing the cells in media with oil concentrations of 0%, 0.5%, and 1.0%. Peking duck, tea tree, and olive oils were used as comparative controls...
September 2015: Poultry Science
https://www.readbyqxmd.com/read/26161938/penetration-enhancing-effects-of-selected-natural-oils-utilized-in-topical-dosage-forms
#9
Joe M Viljoen, Amé Cowley, Jan du Preez, Minja Gerber, Jeanetta du Plessis
CONTEXT: Various natural products, including oils, have been utilized as penetration enhancers due to their "safety profiles". These oils contain fatty acids promoting skin permeability through lipid fluidization within the stratum corneum; and might therefore be able to effectively enhance transdermal drug delivery. OBJECTIVE: We investigated possible penetration enhancing properties of selected oils, utilizing flurbiprofen as marker compound in emulgel formulations...
2015: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/26153074/chemical-profiling-and-anti-psoriatic-activity-of-methanolic-extract-of-andrographis-nallamalayana-j-l-ellis
#10
Sunitha Parlapally, Neeraja Cherukupalli, Sudarshana Reddy Bhumireddy, Prabhakar Sripadi, Ravindernath Anisetti, Charu Chandra Giri, Venkateswara Rao Khareedu, Dashavantha Reddy Vudem
Andrographis nallamalayana is being widely used as tribal medicine in the treatment of leucoderma and mouth ulcers. Chemical profiling of methanolic extract of the whole plant (PE), using GC-MS and LC-MS, revealed the presence of compounds viz. α-tocopherol, β-sitosterol, tetradecanoic acid, monostearin, flavones/flavanones and their glycosides, chromones, etc. Topical application of imiquimod on the dorsal portion of male BALB/C mice resulted in the development of psoriatic symptoms (erythema, scaling, thickening and folding) with a mean disease activity index (DAI) of >7...
June 2016: Natural Product Research
https://www.readbyqxmd.com/read/26080458/efficacy-of-topical-application-of-emu-oil-on-areola-skin-barrier-in-breastfeeding-women
#11
Vincenzo Zanardo, David Giarrizzo, Luigi Maiolo, Gianluca Straface
Appropriate hydration and skin surface pH are of fundamental importance in preventing areola skin barrier damage and breastfeeding success. We studied the dermal effects of emu oil on areola skin soon after birth in 70 at-term breastfeeding mothers by noninvasive bioengineering method. Emu oil-based cream was found to be effective in improving stratum corneum hydration of breast areolae (mean ± standard deviation, from 56.9 ± 18.2 to 65.0 ± 17.2 conventional units, P < .003) and did not affect skin pH, temperature, or elasticity...
January 2016: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/25936812/double-blind-placebo-controlled-pilot-study-of-processed-ultra-emu-oil-versus-placebo-in-the-prevention-of-radiation-dermatitis
#12
RANDOMIZED CONTROLLED TRIAL
Denise C Rollmann, Paul J Novotny, Ivy A Petersen, Yolanda I Garces, Heather J Bauer, Elizabeth S Yan, Dietlind Wahner-Roedler, Ann Vincent, Jeff A Sloan, Nadia N Issa Laack
PURPOSE: The purpose of this single-institution pilot study was to evaluate the feasibility and safety of an oil-based skin agent, Ultra Emu Oil, on skin-related toxicity in patients undergoing radiation therapy to the breast or chest wall. METHODS AND MATERIALS: Patients were randomized 2:1 in a double-blind fashion and were instructed to apply processed Ultra Emu Oil or placebo (cottonseed oil) twice daily during the course of radiation therapy. The oils were applied before the third fraction and continued for 6 weeks after completion of treatment...
July 1, 2015: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/25657781/preparation-and-evaluation-of-minoxidil-foamable-emu-oil-emulsion
#13
M A Shatalebi, Y Rafiei
The aim of this work was to develop and evaluate a minoxidil foamable emu oil emulsion with the purpose of improving minoxidil permeation into the skin, increasing hair growth, reducing skin irritation, and increasing consumer compliance. Minoxidil was dissolved in a solvent system comprising ethanol: glycerin: lactic acid: water (10:20:5:65). The foamable emulsion was prepared by mixing the oil phase with minoxidil solution using different amount of various emulsifiers. Seventeen formulations were prepared and the most stable foamable emulsion was selected and evaluated for various pharmaceutical parameters such as homogeneity, pH, stability to centrifugal stress, freeze-thaw and foamability...
March 2014: Research in Pharmaceutical Sciences
https://www.readbyqxmd.com/read/25625116/evaluation-of-the-clinical-efficacy-and-safety-of-an-eye-counter-pad-containing-caffeine-and-vitamin-k-in-emulsified-emu-oil-base
#14
Fatemeh Ahmadraji, Mohammad Ali Shatalebi
BACKGROUND: People strive to maintain the best look and have a youthful appearance. The skin around the eye is an area without many oil glands and collagen in comparison to the body rest, so it is more prone to fine lines and dehydration, which makes it look dull. The aim of this research is to develop and evaluate in vivo efficacy of an anti-wrinkle and dark circle eye pad consisting of 3% w/w caffeine and 1% vitamin K in a convenient, healthy, and cosmeceutical base. MATERIALS AND METHODS: Pre-emulsions containing selected ingredients in a specified effective concentration were prepared...
2015: Advanced Biomedical Research
https://www.readbyqxmd.com/read/25560991/modulation-of-ppar%C3%AE-and-tnf%C3%AE-by-emu-oil-and-glycyrrhizin-in-ulcerative-colitis
#15
Sri Nandhini Sethuraman, Selvasubramanian Swaminathan, Shinu B Nelson, Preetha S Palaninathan, Tirumurugaan K Gopalan, Pandiyan Velayudham
Ulcerative Colitis (UC) is an inflammatory bowel disorder that affects colon and rectum. Treatments in many UC patients remain variably effective and are associated with considerable adverse effects. So the present study was undertaken to explore the antiinflammatory effects of emu oil, glycyrrhizin, and combination of emu oil and glycyrrhizin in acetic acid-induced UC in rats. UC was induced by intracolonic instillation of 5% acetic acid in rats. Emu oil and glycyrrhizin were orally administered to test groups...
February 2015: Inflammopharmacology
https://www.readbyqxmd.com/read/25441585/review-on-emu-products-for-use-as-complementary-and-alternative-medicine
#16
REVIEW
Manish Kumar Jeengar, P Sravan Kumar, Dinesh Thummuri, Shweta Shrivastava, Lalita Guntuku, Ramakrishna Sistla, V G M Naidu
Emu (Dromaius novaehallandiae), the flightless bird native to Australia and found in many countries, is receiving much attention for its nutritional benefits as well as its medicinal value. Emu oil contains high amounts of polyunsaturated fatty acids and antioxidants. It has potent anti-inflammatory actions and thus can be used topically and orally to treat conditions such as mucositis, inflammatory bowel syndrome, and auricular inflammation, and to prevent chemotherapy-induced bone loss. Emu oil also has a hypocholesterolemic effect, transdermal penetration-enhancing activity, cosmetic and insect repellent activity, and so on...
January 2015: Nutrition
https://www.readbyqxmd.com/read/25301983/synthesis-and-heating-effect-of-iron-iron-oxide-composite-and-iron-oxide-nanoparticles
#17
Q Zeng, I Baker, J A Loudis, Y F Liao, P J Hoopes
Fe/Fe oxide nanoparticles, in which the core consists of metallic Fe and the shell is composed of Fe oxides, were obtained by reduction of an aqueous solution of FeCl3 within a NaBH4 solution, or, using a water-in-oil micro-emulsion with CTAB as the surfactant. The reduction was performed either in an inert atmosphere or in air, and passivation with air was performed to produce the Fe/Fe3O4 core/shell composite. Phase identification and particle size were determined by X-ray diffraction and TEM. Thermal analysis was performed using a differential scanning calorimeter...
February 9, 2007: Proceedings—Society of Photo-Optical Instrumentation Engineers
https://www.readbyqxmd.com/read/25028100/improvement-of-bioavailability-and-anti-inflammatory-potential-of-curcumin-in-combination-with-emu-oil
#18
Manish Kumar Jeengar, Shweta Shrivastava, Kala Nair, Sreenivasa Reddy Singareddy, Uday Kumar Putcha, M V N Kumar Talluri, V G M Naidu, Ramakrishna Sistla
The purpose of the present study is to evaluate the effect of emu oil on bioavailability of curcumin when co-administered and to evaluate the property that enhances the anti-inflammatory potential of curcumin. Oral bioavailability of curcumin in combination with emu oil was determined by measuring the plasma concentration of curcumin by HPLC. The anti-inflammatory potential was evaluated in carrageenan-induced paw edema model (acute model) and in Freund's complete adjuvant (FCA)-induced arthritis model (chronic model) in male SD rats...
December 2014: Inflammation
https://www.readbyqxmd.com/read/24559739/a-new-magnetic-expanded-graphite-for-removal-of-oil-leakage
#19
Xiaohui Ding, Rong Wang, Xin Zhang, Yanzong Zhang, Shihuai Deng, Fei Shen, Xiaohong Zhang, Hong Xiao, Lilin Wang
Magnetic expanded graphite (MEG) was prepared using the blended calcination method under a nitrogen atmosphere. MEG was characterized by scanning electron microscope (SEM), X-ray powder diffraction (XRD), Raman spectroscopy, and vibrating sample magnetization (VSM). Results show that the cobalt ferrite nanoparticles were uniformly and efficiently deposited on expanded graphite (EG). The saturation magnetization reached 55.05 emu g(-1), and the adsorption capacity of MEG under the optimal condition was 35.72 g g(-1) for crude oil...
April 15, 2014: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/24492410/hollow-superparamagnetic-plga-fe3o4-composite-microspheres-for-lysozyme-adsorption
#20
Qi Yang, Yao Wu, Fang Lan, Shaohua Ma, Liqin Xie, Bin He, Zhongwei Gu
Uniform hollow superparamagnetic poly(lactic-co-glycolic acid) (PLGA)/Fe(3)O(4) composite microspheres composed of an inner cavity, PLGA inner shell and Fe(3)O(4) outer shell have been synthesized by a modified oil-in-water (O/W) emulsion-solvent evaporation method using Fe(3)O(4) nanoparticles as a particulate emulsifier. The obtained composite microspheres with an average diameter of 2.5 μm showed excellent monodispersity and stability in aqueous medium, strong magnetic responsiveness, high magnetite content (>68%), high saturation magnetization (58 emu g(-1)) and high efficiency in lysozyme adsorption...
February 28, 2014: Nanotechnology
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