Boyun Yang, Hanxiao Yu, Wo Yao, Ran Diao, Bohui Li, Yongfang Wang, Ting Li, Liuya Ge, Yingying Hu, Huiying Wang
Allergic diseases in children are major public health concerns due to their widespread and rising prevalence. Food-specific immunoglobulin G4(FS-IgG4) has been detected in patients with allergic diseases, but its clinical significance is still debated. In the present study, 407 children with allergic diseases were recruited and categorized into three groups according to the different systems involved: the respiratory system group, the skin system group, and a multiple system group, with the collection of clinical symptoms and serum antibodies, including total immunoglobulin E (IgE), house dust mite (HDM) IgE, food-specific IgE (FS-IgE), and FS-IgG4...
2024: Frontiers in Immunology