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https://www.readbyqxmd.com/read/29225897/-bottom-hung-window-trauma-in-cats-neurological-evaluation-and-outcome-in-71-cats-with-bilateral-hindlimb-injury
#1
Gabriele M Gradner, Lina Dogman-Rauberger, Gilles Dupré
Objectives: Influence of neurological status on the mortality rate of paraparetic/paralysed cats presenting after entrapment in a bottom-hung window was evaluated. It was hypothesised that (1) loss of deep pain sensation at admission would not be a negative prognostic factor for regaining motor function and that (2) mortality rate would be influenced by the severity of neurological grade upon admission. Methods: Clinical and pathological data of affected cats that presented at our institution between 2001 and 2012 for this specific trauma were collected retrospectively: breed, age, sex, last contact with owner (<3 hours and >3 hours), whether the cat was suffering from monoparesis or paraparesis/paraplegia, duration of hospitalisation, rectal temperature, surface temperature of the skin of the hindlimbs, femoral pulse and tone of the pelvic musculature...
2017: Veterinary Record Open
https://www.readbyqxmd.com/read/29198905/the-microbiota-regulates-immunity-and-immunologic-diseases-in-dogs-and-cats
#2
REVIEW
Ian R Tizard, Sydney W Jones
The complex commensal microbiota found on body surfaces controls immune responses and the development of allergic and inflammatory diseases. New genetic technologies permit investigators to determine the composition of the complex microbial populations found on these surfaces. Changes in the microbiota (dysbiosis) as a result of antibiotic use, diet, or other factors thus influence the development of many diseases in the dog and cat. The most important of these include chronic gastrointestinal disease; respiratory allergies, such as asthma; skin diseases, especially atopic dermatitis; and some autoimmune diseases...
November 29, 2017: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/29197056/current-state-of-yusho-and-prospects-for-therapeutic-strategies
#3
Chikage Mitoma, Hiroshi Uchi, Kiyomi Tsukimori, Takashi Todaka, Jumboku Kajiwara, Takayuki Shimose, Manabu Akahane, Tomoaki Imamura, Masutaka Furue
The mass food poisoning incident yusho occurred in Japan in 1968. It was caused by the ingestion of rice bran oil contaminated with polychlorinated biphenyls and various dioxins and dioxin-like compounds including polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDFs). Notably, PCDFs were found to contribute to approximately 65% of the total toxicity equivalent in the blood of yusho patients. Lipophilic dioxins are retained in the body for a longer period than previously estimated. Victims suffered from characteristic skin manifestations associated with non-specific systemic symptoms, neurological symptoms, and respiratory symptoms...
December 1, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29126801/species-differences-between-rat-and-human-in-vitro-metabolite-profile-in-vivo-predicted-clearance-cyp450-inhibition-and-cyp450-isoforms-that-metabolize-benzanthrone-implications-in-risk-assessment
#4
Isha Taneja, Kajal Karsauliya, Mamunur Rashid, Ashish Kumar Sonkar, Kanumuri Siva Rama Raju, Sandeep Kumar Singh, Mukul Das, Muhammad Wahajuddin, Sheelendra Pratap Singh
Benzanthrone (BNZ) is a polycyclic aromatic hydrocarbon found in industrial effluent causing skin, respiratory, gastrointestinal, genitourinary, nervous and hemopoietic toxicity. While its toxicity has been well studied, its metabolism in humans has not been investigated. The aim of this study was to characterize species differences in the in vitro metabolism of BNZ in rat and human liver microsomes and to identify the CYP isoforms involved in its metabolism. Upon incubation in liver microsomes, BNZ was found to be a direct substrate of phase I metabolism in both rat and human, undergoing oxidation and reduction...
November 7, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29118359/visualization-and-quantification-of-injury-to-the-ciliated-epithelium-using-quantitative-flow-imaging-and-speckle-variance-optical-coherence-tomography
#5
Ute A Gamm, Brendan K Huang, Emily K Mis, Mustafa K Khokha, Michael A Choma
Mucociliary flow is an important defense mechanism in the lung to remove inhaled pathogens and pollutants. Disruption of ciliary flow can lead to respiratory infections. Multiple factors, from drugs to disease can cause an alteration in ciliary flow. However, less attention has been given to injury of the ciliated epithelium. In this study, we show how optical coherence tomography (OCT) can be used to investigate injury to the ciliated epithelium in a multi-contrast setting. We used particle tracking velocimetry (PTV-OCT) to investigate the cilia-driven flow field and 3D speckle variance imaging to investigate size and extent of injury caused to the skin of Xenopus embryos...
November 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29116316/characteristics-and-factors-associated-with-hospitalization-in-early-childhood-2004-pelotas-brazil-birth-cohort
#6
Vera Lucia Schmidt da Silva, Giovanny Vinícius Araújo de França, Iná S Santos, Fernando C Barros, Alícia Matijasevich
Hospitalization is a frequent event in early childhood. In Brazil, the National Household Sample Survey of 2008 showed a 9% hospitalization rate among children in the first four years of life. The study aimed to describe the characteristics of hospitalization in the first six years of life and analyze the early factors associated with hospitalization in a birth cohort in southern Brazil. A zero-inflated Poisson model was used to simultaneously examine the effects of co-variables for the occurrence of a given event and to count events...
November 6, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/29077993/epidemiology-of-staphylococcal-scalded-skin-syndrome-in-united-states-children
#7
A Staiman, D Y Hsu, J I Silverberg
BACKGROUND: Staphylococcal scalded skin syndrome (SSSS) is a blistering dermatosis caused by exfoliative toxins released from Staphylococcus aureus. We sought to describe the incidence, costs, length of stay (LOS), comorbidities, and mortality of SSSS in US children. METHODS: The Nationwide Inpatient Sample 2008-2012 was analyzed, including a 20% sample of US hospitalizations and 589 cases of SSSS. RESULTS: The annual incidence of SSSS was 7...
October 27, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/29063426/introduction
#8
Erica A Fortson, Becky Li, Mahima Bhayana
Atopic dermatitis (AD) is a chronic relapsing condition that is characterized by itching and redness of the skin. Our modern usage of atopic dermatitis dates back to 1933, when Wise and Sulzberger first coined the term to signify the disease's close association with other respiratory atopy, such as bronchial asthma and allergic rhinitis. A recent systematic review of 69 cross-sectional and cohort studies has confirmed that AD is now a worldwide phenomenon with lifetime AD prevalences of well over 20% in many affluent country settings...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29045689/sensitivity-to-house-dust-mites-allergens-with-atopic-asthma-and-its-relationship-with-cd14-c-159t-polymorphism-in-patients-of-west-bengal-india
#9
Amlan Ghosh, Shampa Dutta, Sanjoy Podder, Priti Mondal, Arghya Laha, Nimai Chandra Saha, Saibal Moitra, Goutam Kumar Saha
India is the home to around 15-20 million asthmatics, and asthma prevalence is increasing in Indian metropolitan area, including Kolkata, West Bengal. Complex interactions of genetic and environmental factors are involved in asthma. Genome-wide search for susceptible loci regulating IgE response (atopy) have identified a candidate gene CD14 which is most important in the context of allergic responses of respiratory system. This study was aimed to investigate the role of house dust and house dust mites in development of bronchial asthma and to explore the possible association of candidate gene CD14 with disease manifestation among Kolkata patient population...
October 17, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29037654/systemic-sclerosis-association-between-physical-function-handgrip-strength-and-pulmonary-function
#10
Agnaldo José Lopes, Amanda Cristina Justo, Arthur Sá Ferreira, Fernando Silva Guimaraes
BACKGROUND: Systemic sclerosis (SSc) is a multisystem disease affecting the skin, respiratory system and skeletal muscles. In SSc patients, hand function disability is the major factor limiting daily activities. AIM: To evaluate the association of physical function with handgrip strength and pulmonary function in SSc patients. A further aim was to assess the relationship between handgrip strength and pulmonary function in patients with SSc. METHOD: A cross-sectional study in which 28 patients with SSc underwent isometric handgrip strength (IHGS) measurement and pulmonary function tests and completed the Health Assessment Questionnaire Disability Index (HAQ-DI) to measure physical function...
October 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29022537/respiratory-comorbidity-in-south-african-children-with-atopic-dermatitis
#11
C L Gray, M E Levin, G Du Toit
BACKGROUND: Atopic dermatitis (AD) is an early and important step in the propagation of the allergic march, enhancing food and respiratory allergies via epicutaneous sensitisation to allergens. OBJECTIVES: To determine the prevalence and patterns of aeroallergen sensitisation, asthma and allergic rhinitis in South African (SA) children with AD. METHODS: This was a prospective, observational study in a paediatric university hospital in Cape Town, SA...
September 22, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28992352/in-vivo-pathogenicity-of-trichosporon-asahii-isolates-with-different-in-vitro-enzymatic-profiles-in-an-immunocompetent-murine-model-of-systemic-trichosporonosis
#12
Alexandra M Montoya, Carolina E Luna-Rodríguez, Rogelio de J Treviño-Rangel, Miguel Becerril-García, Raquel G Ballesteros-Elizondo, Odila Saucedo-Cárdenas, Gloria M González
Trichosporon asahii is an opportunistic yeastlike fungus that colonizes the gastrointestinal and respiratory tracts and human skin. Although it is an important cause of disseminated infections by non-Candida species, there are a few reports related to its virulence factors and their possible role in in vivo pathogenicity. We developed a murine model of disseminated trichosporonosis in immunocompetent mice for the evaluation of the in vivo pathogenicity of 6 T. asahii isolates with different in vitro virulence factor profiles...
September 9, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28992033/veal-calf-health-on-the-day-of-arrival-at-growers-in-ohio
#13
J Pempek, D Trearchis, M Masterson, G Habing, K Proudfoot
Veal calves are at high risk for disease and mortality in early life. Calves face a number of stressors before arriving at the grower, including long transport times, which may contribute to poor health. Our objectives were to 1) estimate the prevalence of poor health outcomes in veal calves on arrival at growers in Ohio; 2) determine risk factors for health outcomes on arrival, including BW and auction site (spread across 5 states in the Northeastern United States); and 3) determine if health outcomes on arrival predict early mortality...
September 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28967432/dermal-exposure-to-toluene-diisocyanate-and-respiratory-cancer-risk
#14
REVIEW
Robyn L Prueitt, Heather N Lynch, Ke Zu, Liuhua Shi, Julie E Goodman
Human exposure to toluene diisocyanate (TDI) occurs mainly through inhalation of vapors in occupational settings where TDI is produced or used, but dermal exposure to TDI is also possible during some operations. Because of a recent epidemiology study reporting a possible association with lung cancer risk in workers with potential dermal exposure to TDI, we evaluated the evidence from epidemiological, toxicological, and toxicokinetic studies to assess whether it is likely that dermal exposure to TDI can cause human respiratory cancers...
December 2017: Environment International
https://www.readbyqxmd.com/read/28943132/types-and-microbiological-spectrum-of-infections-in-patients-with-cirrhosis-a-single-centre-experience-in-upper-egypt
#15
Hussein El-Amin, Abeer M M Sabry, Rabab E Ahmed, Nahed A Makhlouf
BACKGROUND AND STUDY AIMS: Egypt has a high prevalence of hepatitis C virus (HCV) and high morbidity and mortality related to cirrhosis complications. Patients with cirrhosis have an increased risk of bacterial infections. Approximately 25-35% of cirrhotics had infections at admission or during hospitalisation. Data on infection among cirrhotics in Egypt are limited. This study aimed to determine the frequency and microbiological spectrum of infections in cirrhotics and possible risk factors...
September 2017: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/28913989/patterns-of-inhalant-allergen-sensitization-and-geographical-variation-in-korean-adults-a-multicenter-retrospective-study
#16
Min Gyu Kang, Mi Yeong Kim, Woo Jung Song, Sujeong Kim, Eun Jung Jo, Seung Eun Lee, Jae Woo Kwon, Sang Min Lee, Chan Sun Park, Hye Kyung Park, Heung Woo Park, Yoon Seok Chang, Jaechun Lee, Young Min Lee, Young Koo Jee, Jong Myung Lee, Inseon S Choi, Sang Heon Cho
PURPOSE: Inhalant allergen sensitization is one of the major factors involved in the pathogenesis of allergic respiratory diseases. However, the sensitization is determined by interactions between genetic and environmental factors. Thus, testing panels of inhalant allergens may differ among geographical areas. Here we aimed to determine 10 common inhalant allergens in Korean adult patients with suspected respiratory allergies and to examine the variation between different geographical locations...
November 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28840092/smear-grading-and-the-mantoux-skin-test-can-be-used-to-predict-sputum-smear-conversion-in-patients-suffering-from-tuberculosis
#17
Mahmood Saffari, Hadis Alizadeh Jolandimi, Mojtaba Sehat, Nastarn Vali Nejad, Mehrdad Hedayati, Mahbobeh Zamani, Amir Ghasemi
Purpose: Smear scores and induration sizes resulting from the PPD (tuberculin purified protein derivative) test can serve as indicators of whether a patient suffering from tuberculosis shows smear conversion or not. Methods: Using microbiological methods smear and sputum tests, patients diagnosed as infected with Mycobacterium tuberculosis between 2002 and 2015 were included in this study. All of the assumed factors that may have a role in smear conversion were studied, in addition to the prolongation of tuberculosis...
2017: GMS Hygiene and Infection Control
https://www.readbyqxmd.com/read/28829345/allergies-and-exercise-induced-bronchoconstriction-in-a-youth-academy-and-reserve-professional-soccer-team
#18
Valérie Bougault, François Drouard, Franck Legall, Grégory Dupont, Benoit Wallaert
OBJECTIVES: A high prevalence of respiratory allergies and exercise-induced bronchoconstriction (EIB) has been reported among endurance athletes. This study was designed to analyze the frequency of sensitization to respiratory allergens and EIB in young soccer players. DESIGN: Prospective cohort design. SETTING: Youth academy and reserve professional soccer team during the seasons 2012 to 2013 and 2013 to 2014. PARTICIPANTS: Eighty-five soccer players (mean age: 20 ± 4 years) participated...
September 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28783215/sensitization-to-dust-mite-defines-different-phenotypes-of-asthma-a-multicenter-study
#19
Silvia Ruggieri, Gaspare Drago, Valeria Longo, Paolo Colombo, Martin Balzan, David Bilocca, Christopher Zammit, Stephen Montefort, Gianluca Scaccianoce, Giuseppina Cuttitta, Giovanni Viegi, Fabio Cibella
BACKGROUND: Indoor allergens are risk factors for asthma: Thus, the characterization of indoor air quality is important for studying environment-health relationships in children. In particular, Dermatophagoides pteronyssinus is the dominant allergen for asthma. We cross-sectionally investigated the relationships among respiratory symptoms and function, airway inflammation, allergen sensitization, and indoor allergen concentration. METHODS: One hundred and thirty-two children aging 10-14 years and living in a Southern Mediterranean area were evaluated by parental questionnaires...
November 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28775385/-guidelines-for-the-preventive-health-care-of-hairdressing-apprentices
#20
Aleksandra Golińska-Zach, Marta Wiszniewska, Jolanta Walusiak-Skorupa
Hairdressing is one of the most developing branch of the service industry in Poland. Providing representatives of this occupational group with preventive health care services it should be remembered that they are at risk of skin and respiratory diseases, which occur due to a quite frequent exposure to harmful agents in the work environment of hairdressers and hairdressing apprentices. Interestingly, a much lower number of researches concentrate on respiratory symptoms than on skin disorders in hairdressers...
July 26, 2017: Medycyna Pracy
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