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https://www.readbyqxmd.com/read/27902522/the-effect-of-topical-use-of-petroselinum-crispum-parsley-versus-that-of-hydroquinone-cream-on-reduction-of-epidermal-melasma-a-randomized-clinical-trial
#1
Shahla Khosravan, Ali Alami, Hossein Mohammadzadeh-Moghadam, Vahide Ramezani
Melasma disfigures the skin and thus influences people's self-image and self-concept. Therefore, melasma influences emotional and psychosocial health in addition to physical health. This clinical trial was performed to assess the effect of the topical use of Petroselinum crispum (parsley) on reduction of the severity of epidermal melasma.
January 2017: Holistic Nursing Practice
https://www.readbyqxmd.com/read/27885677/chemical-composition-of-microalgae-heterochlorella-luteoviridis-and-dunaliella-tertiolecta-with-emphasis-on-carotenoids
#2
Andressa Bacalau Diprat, Tania Menegol, Juliana Ferreira Boelter, Ariane Zmozinski, Maria Goreti Rodrigues Vale, Eliseu Rodrigues, Rosane Rech
BACKGROUND: Microalgae have been used as food supplements due their high protein, polyunsaturated fatty acids and carotenoid contents. As different carotenoids have distinct properties, and carotenoid composition from microalgae were poorly explored in the literature, this study determined the complete carotenoid composition from two microalgae species, Heterochlorella luteoviridis and Dunaliella tertiolecta, using high-performance liquid chromatography coupled to diode array detector and a mass spectrometry (HPLC-DAD-MS(2) )...
November 24, 2016: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/27862006/developmental-sexual-dimorphism-and-the-evolution-of-mechanisms-for-adjustment-of-sex-ratios-in-mammals
#3
Elissa Z Cameron, Amy M Edwards, Laura M Parsley
Sex allocation theory predicts biased offspring sex ratios in relation to local conditions if they would maximize parental lifetime reproductive return. In mammals, the extent of the birth sex bias is often unpredictable and inconsistent, leading some to question its evolutionary significance. For facultative adjustment of sex ratios to occur, males and females would need to be detectably different from an early developmental stage, but classic sexual dimorphism arises from hormonal influences after gonadal development...
November 18, 2016: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/27812547/acute-hemodynamic-effects-of-inhaled-sodium-nitrite-in-pulmonary-hypertension-associated-with-heart-failure-with-preserved-ejection-fraction
#4
Marc A Simon, Rebecca R Vanderpool, Mehdi Nouraie, Timothy N Bachman, Pamela M White, Masataka Sugahara, John Gorcsan, Ed L Parsley, Mark T Gladwin
BACKGROUND: Pulmonary hypertension (PH) is associated with poor outcomes, yet specific treatments only exist for a small subset of patients. The most common form of PH is that associated with left heart disease (Group 2), for which there is no approved therapy. Nitrite has shown efficacy in preclinical animal models of Group 1 and 2 PH, as well as in patients with left heart failure with preserved ejection fraction (HFpEF). We evaluated the safety and efficacy of a potentially novel inhaled formulation of nitrite in PH-HFpEF patients as compared with Group 1 and 3 PH...
November 3, 2016: JCI Insight
https://www.readbyqxmd.com/read/27807783/assessment-of-uptake-and-phytotoxicity-of-cyanobacterial-extracts-containing-microcystins-or-cylindrospermopsin-on-parsley-petroselinum-crispum-l-and-coriander-coriandrum-sativum-l
#5
Ana L Pereira, Joana Azevedo, Vitor Vasconcelos
Blooms of harmful cyanobacteria that synthesize cyanotoxins are increasing worldwide. Agronomic plants can uptake these cyanotoxins and given that plants are ultimately ingested by humans, this represents a public health problem. In this research, parsley and coriander grown in soil and watered through 7 days with crude extracts containing microcystins (MCs) or cylindrospermopsin (CYN) in 0.1-1 μg mL(-1) concentration range were evaluated concerning their biomass, biochemical parameters and uptake of cyanotoxins...
November 2, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27795735/respiration-activity-monitoring-system-for-any-individual-well-of-a-48-well-microtiter-plate
#6
David Flitsch, Sebastian Krabbe, Tobias Ladner, Mario Beckers, Jana Schilling, Stefan Mahr, Uwe Conrath, Werner K Schomburg, Jochen Büchs
BACKGROUND: Small-scale micro-bioreactors have become the cultivation vessel of choice during the first steps of bioprocess development. They combine high cultivation throughput with enhanced cost efficiency per cultivation. To gain the most possible information in the early phases of process development, online monitoring of important process parameters is highly advantageous. One of these important process parameters is the oxygen transfer rate (OTR). Measurement of the OTR, however, is only available for small-scale fermentations in shake flasks via the established RAMOS technology until now...
2016: Journal of Biological Engineering
https://www.readbyqxmd.com/read/27771948/level-of-alkenylbenzenes-in-parsley-and-dill-based-teas-and-associated-risk-assessment-using-the-margin-of-exposure-approach
#7
Abdalmajeed M Alajlouni, Amer J Almalahmeh, Farida Nur Isnaeni, Sebastiaan Wesseling, Jacques Vervoort, Ivonne Magdalena Catharina Maria Rietjens
Risk assessment of parsley and dill based teas that contain alkenylbenzenes was performed. To this end the estimated daily intake (EDI) of alkenylbenzenes resulting from use of the teas was quantified. Since most teas appeared to contain more than one alkenylbenzene a combined risk assessment was performed based on equal potency of all alkenylbenzenes or using a so-called Toxic Equivalency (TEQ) approach through defining Toxic Equivalency Factors (TEFs) for the different alkenylbenzenes. The EDI values resulting from consuming one cup of tea a day were 0...
October 22, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27766890/pharmacokinetic-properties-and-drug-interactions-of-apigenin-a-natural-flavone
#8
Ding Tang, Keli Chen, Luqi Huang, Juan Li
Apigenin, a natural flavone, is widely distributed in plants such as celery, parsley and chamomile. It is present principally as glycosylated in nature. Higher intake of apigenin could reduce the risk of chronic diseases. It has gained particular interest in recent years as a beneficial, health-promoting agent with low intrinsic toxicity. Areas covered: This review summarizes and the absorption, distribution, metabolism and excretion (ADME) properties of apigenin, and drug-drug interaction of apigenin. Expert opinion: Since apigenin is a bioactive plant flavone and is widely distributed in common food, its consumption through the diet is recommended...
October 21, 2016: Expert Opinion on Drug Metabolism & Toxicology
https://www.readbyqxmd.com/read/27756017/consumers-sensitivity-to-androstenone-and-the-evaluation-of-different-cooking-methods-to-mask-boar-taint
#9
F Borrisser-Pairó, N Panella-Riera, M Gil, Z Kallas, M B Linares, M Egea, M D Garrido, M A Oliver
Boar taint is an unpleasant odour and flavour present in some entire male pigs that is due to the presence of androstenone and skatole. The aim of the study was to assess the sensitivity of 150 consumers to androstenone and to compare the acceptability and liking of meat from castrated and entire pigs, cooked with different cooking methods. Meat samples consisted of loins from castrated (CM) and entire male pigs (EM) with high levels of androstenone cooked by two cooking methods: sous-vide and fried/breaded with garlic and parsley...
October 13, 2016: Meat Science
https://www.readbyqxmd.com/read/27746803/suitable-reference-genes-for-accurate-gene-expression-analysis-in-parsley-petroselinum-crispum-for-abiotic-stresses-and-hormone-stimuli
#10
Meng-Yao Li, Xiong Song, Feng Wang, Ai-Sheng Xiong
Parsley, one of the most important vegetables in the Apiaceae family, is widely used in the food, medicinal, and cosmetic industries. Recent studies on parsley mainly focus on its chemical composition, and further research involving the analysis of the plant's gene functions and expressions is required. qPCR is a powerful method for detecting very low quantities of target transcript levels and is widely used to study gene expression. To ensure the accuracy of results, a suitable reference gene is necessary for expression normalization...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27706237/inducible-expression-of-the-de-novo-designed-antimicrobial-peptide-sp1-1-in-tomato-confers-resistance-to-xanthomonas-campestris-pv-vesicatoria
#11
Areli Herrera Diaz, Izabella Kovacs, Christian Lindermayr
Antimicrobial peptides (AMPs) are small peptides with less than 50 amino acids and are part of the innate immune response in almost all organisms, including bacteria, vertebrates, invertebrates and plants. AMPs are active against a broad-spectrum of pathogens. The inducible expression of AMPs in plants is a promising approach to combat plant pathogens with minimal negative side effects, such as phytotoxicity or infertility. In this study, inducible expression of the de-novo designed AMP SP1-1 in Micro Tom tomato protected tomato fruits against bacterial spot disease caused by Xanthomonas campestris pv...
2016: PloS One
https://www.readbyqxmd.com/read/27704219/abundant-collateralization-of-temporal-lobe-projections-to-the-accumbens-bed-nucleus-of-stria-terminalis-central-amygdala-and-lateral-septum
#12
Rhett A Reichard, Suriya Subramanian, Mikiyas T Desta, Tej Sura, Mary L Becker, Comeron W Ghobadi, Kenneth P Parsley, Daniel S Zahm
Behavioral flexibility is subserved in part by outputs from the cerebral cortex to telencephalic subcortical structures. In our earlier evaluation of the organization of the cortical-subcortical output system (Reynolds and Zahm, J Neurosci 25:11757-11767, 2005), retrograde double-labeling was evaluated in the prefrontal cortex following tracer injections into pairs of the following subcortical telencephalic structures: caudate-putamen, core and shell of the accumbens (Acb), bed nucleus of stria terminalis (BST) and central nucleus of the amygdala (CeA)...
October 4, 2016: Brain Structure & Function
https://www.readbyqxmd.com/read/27677090/red-light-dose-or-wavelength-dependent-photoresponse-of-antioxidants-in-herb-microgreens
#13
Giedė Samuolienė, Aušra Brazaitytė, Akvilė Viršilė, Julė Jankauskienė, Sandra Sakalauskienė, Pavelas Duchovskis
The purpose of this study was to evaluate the role of 638-nm and 665-nm LEDs on changes of antioxidants of basil (Ocimum basilicum) and parsley (Petroselinum crispum), and to assess the effect of light quality on antioxidative status. Plants were grown in peat substrate for 19 days (21/17 ±2°C, 16 h). Experiments were performed in (I) a controlled-environment: B455,R638,R665,FR731(control); B455,R*638,R665,FR731; B455,R638,R*665,FR731; R638; R665 (B-blue, R- red, FR-far-red light). PPFD was set from 231 during growth, upto 300 μmol m-2 s-1 during 3-day treatment changing R638 or R665 PPFD level; in (II) greenhouse (November): high-pressure sodium lamps (HPS) (control-300 μmol m-2s-1); and HPS + 638 (HPS generated 90 and red LEDs-210 μmol m-2s-1)...
2016: PloS One
https://www.readbyqxmd.com/read/27651256/role-of-quercetin-benefits-in-neurodegeneration
#14
Preetham Elumalai, Sreeja Lakshmi
Neurodegenerative disorders are often life threatening and hired as an economic burden to the health-care system. Nutritional interventions principally involving polyphenols were practiced to arrest or reverse the age-related health disorders. Flavonoids, a class of dietary polyphenols, are rising to superstardom in preventing brain disorders with their potent antioxidant defense mechanism. Quercetin is a ubiquitous flavonoid reported to have all-natural myriad of health benefits. Citrus fruits, apple, onion, parsley, berries, green tea, and red wine comprise the major dietary supplements of quercetin apart from some herbal remedies like Ginkgo biloba...
2016: Advances in Neurobiology
https://www.readbyqxmd.com/read/27557767/analysis-of-microbe-associated-molecular-pattern-responsive-synthetic-promoters-with-the-parsley-protoplast-system
#15
Konstantin Kanofsky, Mona Lehmeyer, Jutta Schulze, Reinhard Hehl
Plants recognize pathogens by microbe-associated molecular patterns (MAMPs) and subsequently induce an immune response. The regulation of gene expression during the immune response depends largely on cis-sequences conserved in promoters of MAMP-responsive genes. These cis-sequences can be analyzed by constructing synthetic promoters linked to a reporter gene and by testing these constructs in transient expression systems. Here, the use of the parsley (Petroselinum crispum) protoplast system for analyzing MAMP-responsive synthetic promoters is described...
2016: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27525894/antifungal-and-antibacterial-activities-of-petroselinum-crispum-essential-oil
#16
G A Linde, Z C Gazim, B K Cardoso, L F Jorge, V Tešević, J Glamoćlija, M Soković, N B Colauto
Parsley [Petroselinum crispum (Mill.) Fuss] is regarded as an aromatic, culinary, and medicinal plant and is used in the cosmetic, food, and pharmaceutical industries. However, few studies with conflicting results have been conducted on the antimicrobial activity of parsley essential oil. In addition, there have been no reports of essential oil obtained from parsley aerial parts, except seeds, as an alternative natural antimicrobial agent. Also, microorganism resistance is still a challenge for health and food production...
2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27450280/guinea-pig-cavia-porcellus-drinking-preferences-do-nipple-drinkers-compensate-for-behaviourally-deficient-diets
#17
A Balsiger, M Clauss, A Liesegang, B Dobenecker, J-M Hatt
When offered diets with hay ad libitum, rabbits (Oryctolagus cuniculus) clearly prefer open dishes over nipple drinkers, but whether this preference also applies in guinea pigs (Cavia porcellus) is unsure. We tested the drinker preference of 10 guinea pigs when offered open dishes (OD) and nipple drinkers (ND) simultaneously and measured the amount of water consumed by each animal on four different diets (grass hay 100%, or as 10% of intake on diets of fresh parsley, seed mix or pelleted complete feed, respectively) on either of the drinking systems...
July 23, 2016: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/27447854/clinical-benefit-of-a-precision-medicine-based-approach-for-guiding-treatment-of-refractory-cancers
#18
Milan Radovich, Patrick J Kiel, Stacy M Nance, Erin E Niland, Megan E Parsley, Meagan E Ferguson, Guanglong Jiang, Natraj R Ammakkanavar, Lawrence H Einhorn, Liang Cheng, Mehdi Nassiri, Darrell D Davidson, Daniel A Rushing, Patrick J Loehrer, Roberto Pili, Nasser Hanna, J Thomas Callaghan, Todd C Skaar, Paul R Helft, Safi Shahda, Bert H O'Neil, Bryan P Schneider
PATIENTS AND METHODS: Patients with metastatic solid tumors who had progressed on at least one line of standard of care therapy were referred to the Indiana University Health Precision Genomics Program. Tumor samples were submitted for DNA & RNA next-generation sequencing, fluorescence in situ hybridization, and immunohistochemistry for actionable targets. A multi-disciplinary tumor board reviewed all results. For each patient, the ratio of progression-free survival (PFS) of the genomically guided line of therapy divided by the PFS of their prior line was calculated...
July 15, 2016: Oncotarget
https://www.readbyqxmd.com/read/27421086/first-detection-of-toxoplasma-gondii-dna-in-the-fresh-leafs-of-vegetables-in-south-america
#19
Ariella A Marchioro, Bruna T Tiyo, Cristiane M Colli, Carla Z de Souza, João L Garcia, Mônica L Gomes, Ana L Falavigna-Guilherme
Despite the high dispersion of Toxoplasma gondii oocysts in the environment, there are few studies investigating their presence in vegetables consumed by the general population. This has led us to investigate its occurrence in raw vegetables. A total of 238 samples of vegetables were collected, including crisp lettuce, regular lettuce, chicory, rocket, and parsley, both organic and nonorganic, locally in northwestern Parana, Southern Brazil. Each sample (50 g) was washed and filtered separately. A PCR was performed to detect the parasite DNA from the sediment of each sample, using B1 (B22-23) and Toxo4-5 primers...
September 2016: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/27302434/investigation-of-parasitic-contaminations-of-vegetables-sold-in-markets-in-the-city-of-tabriz-in-2014
#20
Davoud Balarak, Masomeh Ebrahimi, Mohammad Jafari Modrek, Edris Bazrafshan, Amir Hossein Mahvi, Yousef Mahdavi
Parasitic diseases are among the most common problems in developing countries. Various parasitic forms such as cysts, larvae and eggs of the parasite are transmitted orally through the consumption of vegetables. So, the aim of this study was to evaluate parasitic contamination of fresh vegetables consumed in the city of Tabriz. This cross-sectional study was conducted for 3 months in 2014 in Tabriz. In this study, 1620 samples from 10 kinds of vegetables (leeks, basil, mint, chives, radishes, parsley, lettuce, watercress, tarragon and coriander) were collected from 54 vegetable shops...
1, 2016: Global Journal of Health Science
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