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https://www.readbyqxmd.com/read/29140397/progress-in-the-understanding-of-the-pathology-of-allergic-asthma-and-the-potential-of-fruit-proanthocyanidins-as-modulators-of-airway-inflammation
#1
REVIEW
Sara L Coleman, Odette M Shaw
Allergic asthma is a chronic inflammatory lung disease characterized by sensitization of the airways, and the development of immunoglobulin E antibodies, to benign antigens. The established pathophysiology of asthma includes recurrent lung epithelial inflammation, excessive mucus production, bronchial smooth muscle hyperreactivity, and chronic lung tissue remodeling, resulting in reversible airflow restriction. Immune cells, including eosinophils and the recently characterized type 2 innate lymphoid cells, infiltrate into the lung tissue as part of the inflammatory response in allergic asthma...
November 15, 2017: Food & Function
https://www.readbyqxmd.com/read/29127476/co-supplementation-of-isomalto-oligosaccharides-potentiates-metabolic-health-benefits-of-polyphenol-rich-cranberry-extract-in-high-fat-diet-fed-mice-via-enhanced-gut-butyrate-production
#2
Dhirendra Pratap Singh, Shashank Singh, Vandana Bijalwan, Vijay Kumar, Pragyanshu Khare, Ritesh Kumar Baboota, Paramdeep Singh, Ravneet Kaur Boparai, Jagdeep Singh, Kanthi Kiran Kondepudi, Kanwaljit Chopra, Mahendra Bishnoi
PURPOSE: Cranberries are a rich source of polyphenolic antioxidants. Purified sugars or artificial sweeteners are being added to cranberry-based food products to mask tartness. Refined sugar and artificial sweeteners intake modulate gut microbiota and result in metabolic complications. We evaluated effects of isomalto-oligosaccharides (IMOs; sweet tasting non-digestible oligosaccharides) with cranberry extract (CRX) on high fat diet (HFD)-induced metabolic alterations in mice. METHODS: Male Swiss albino mice were fed normal chow or HFD (58% fat kcal), and were administered either CRX (200 mg/kg) alone or in combination with IMOs (1 g/kg)...
November 10, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/29111902/the-effect-of-cranberry-juice-consumption-on-the-recurrence-of-urinary-tract-infection-relationship-to-baseline-risk-factors
#3
Kevin C Maki, Kristin M Nieman, Arianne L Schild, Kerrie L Kaspar, Christina Khoo
OBJECTIVE: The objective of this study was to assess relationships between clinical predictors of urinary tract infection (UTI) and effects of cranberry juice consumption on recurrence in a post hoc analysis of a 24-week, randomized, double-blind, placebo-controlled, multicenter clinical trial in women with a recent history of UTI. METHODS: Participants consumed a cranberry (n = 185) or placebo (n = 188) beverage (240 mL) daily. Odds ratios (OR) from 20 candidate predictor variables were evaluated in univariate analyses to assess clinical UTI incidence relationships in the placebo group...
November 7, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29107524/a-polyphenol-rich-cranberry-extract-reverses-insulin-resistance-and-hepatic-steatosis-independently-of-body-weight-loss
#4
Fernando F Anhê, Renato T Nachbar, Thibault V Varin, Vanessa Vilela, Stéphanie Dudonné, Geneviève Pilon, Maryse Fournier, Marc-André Lecours, Yves Desjardins, Denis Roy, Emile Levy, André Marette
OBJECTIVE: Previous studies have reported that polyphenol-rich extracts from various sources can prevent obesity and associated gastro-hepatic and metabolic disorders in diet-induced obese (DIO) mice. However, whether such extracts can reverse obesity-linked metabolic alterations remains unknown. In the present study, we aimed to investigate the potential of a polyphenol-rich extract from cranberry (CE) to reverse obesity and associated metabolic disorders in DIO-mice. METHODS: Mice were pre-fed either a Chow or a High Fat-High Sucrose (HFHS) diet for 13 weeks to induce obesity and then treated either with CE (200 mg/kg, Chow + CE, HFHS + CE) or vehicle (Chow, HFHS) for 8 additional weeks...
October 18, 2017: Molecular Metabolism
https://www.readbyqxmd.com/read/29072566/does-cranberry-have-a-role-in-catheter-associated-urinary-tract-infections
#5
Dominique Thomas, Matthew Rutman, Kimberly Cooper, Andrew Abrams, Julia Finkelstein, Bilal Chughtai
INTRODUCTION: Catheter-associated urinary tract infections (CA-UTIs) are a prevalent and costly condition, with very few therapeutic options. We sought to evaluate the efficacy of an oral cranberry supplement on catheter-associated urinary tracts infections over a six-month period. METHODS: Subjects with long-term indwelling catheters and recurrent symptomatic CA-UTIs were enrolled to take a once-daily cranberry supplement - an oral cranberry supplement with 36 mg of the active ingredient proanthocyanidin (PACs)...
November 11, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29064320/the-hospital-acquired-conditions-hac-reduction-program-using-cranberry-treatment-to-reduce-catheter-associated-urinary-tract-infections-and-avoid-medicare-payment-reduction-penalties
#6
T L Saitone, R J Sexton, A Sexton Ward
OBJECTIVE: The Affordable Care Act (ACA) established the Hospital-Acquired Condition (HAC) Reduction Program. The Centers for Medicare and Medicaid Services (CMS) established a total HAC scoring methodology to rank hospitals based upon their HAC performance. Hospitals that rank in the lowest quartile based on their HAC score are subject to a 1% reduction in their total Medicare reimbursements. In FY 2017, 769 hospitals incurred payment reductions totaling $430 million. This study analyzes how improvements in the rate of catheter-associated urinary tract infections (CAUTI), based on the implementation of a cranberry-treatment regimen, impact hospitals' HAC scores and likelihood of avoiding the Medicare-reimbursement penalty...
November 14, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/29046404/cranberry-reduces-the-risk-of-urinary-tract-infection-recurrence-in-otherwise-healthy-women-a-systematic-review-and-meta-analysis
#7
Zhuxuan Fu, DeAnn Liska, David Talan, Mei Chung
Background: Cranberry (Vaccinium spp.) has been advocated for treatment of urinary tract infection (UTI); however, its efficacy is controversial. Women have a 50% risk of UTI over their lifetime, and ∼20-30% experience a subsequent UTI recurrence.Objective: We conducted this meta-analysis to assess the effect of cranberry on the risk of UTI recurrence in otherwise healthy women.Methods: Literature published before January 2011 was obtained from 2 published systematic reviews, and we conducted updated searches in EMBASE and MEDLINE (through July 2017)...
October 18, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/29038797/anthocyanin-profile-antioxidant-activity-and-enzyme-inhibiting-properties-of-blueberry-and-cranberry-juices-a-comparative-study
#8
Guillermo Cásedas, Francisco Les, María Pilar Gómez-Serranillos, Carine Smith, Víctor López
Cranberry (Vaccinium macrocarpon) and blueberry (Vaccinium myrtillus) juices are commonly consumed as a source of antioxidants. The aim of this study was to compare bioactivities as well as the differences in the polyphenol content and anthocyanin profile of both juices. Polyphenol and anthocyanin contents were quantified using spectrophotometric and chromatographic methods. Bioassays were carried out in terms of antioxidant properties in cell and cell free systems as well as inhibition of physiological enzymes that are targets involved in the prevention of chronic diseases (monoamine oxidase A, tyrosinase, acetylcholinesterase, α-glucosidase and dipeptidyl peptidase-4)...
October 17, 2017: Food & Function
https://www.readbyqxmd.com/read/29033364/-recurrent-cystisis-no-medicine-preventive-means
#9
A Julien
OBJECTIVE: To estimate from the literature review, the interest of hygienic and behavioural measures and the use of food supplements (herbal) to prevent female urinary tract infection. METHODS: Pubmed research was focused on the efficiency of prophylactic measures in recurrent cystisis management. RESULTS: Due to many predisposing factors such as anatomical charasteristics, hydration and lifestyle, cystisis is more common in female subjects than in male...
November 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/29028333/profiling-and-quantification-of-regioisomeric-caffeoyl-glucoses-in-berry-fruits
#10
Maria Alexandra Patras, Nikolai Kuhnert, Rakesh Jaiswal, Gordon J McDougall
Based on a recently developed tandem MS based hierarchical scheme for the identification of regioisomeric caffeoyl glucoses, selected berry fruits were profiled for their caffeoyl glucose ester content. Fresh edible berries profiled included strawberries, raspberries, blueberries, blackberries, red and black currants, lingonberries, gooseberries, cranberries, juice of elderberries, goji berries, chokeberries, cranberries, açai berries, sea buckthorn berries, Montmorency sour cherries, and pomegranate were investigated...
October 13, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28987724/effect-of-proanthocyanidin-enriched-extracts-on-the-inhibition-of-wear-and-degradation-of-dentin-demineralized-organic-matrix
#11
Ana Paula Boteon, Melissa Thiemi Kato, Marília Afonso Rabelo Buzalaf, Anuradha Prakki, Linda Wang, Daniela Rios, Heitor Marques Honório
OBJECTIVES: The aim of this study was to evaluate the effect of Cranberry and Grape seed-enriched extract gels in inhibiting wear and degradation of demineralized organic matrix (DOM). DESIGN: 225 dentin specimens obtained from bovine incisors were randomly allocated into 5 groups (n=45): 10% Grape seed extract gel (GSE), 10% Cranberry extract gel (CE), 0.012% Chlorhexidine gel (CX), 1.23% NaF gel (F), and no active compound gel (P, placebo). Before the treatments, samples were demineralized by immersion in 0...
September 25, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28982414/single-laboratory-validation-for-determination-of-total-soluble-proanthocyanidins-in-cranberry-using-4-dimethylaminocinnamaldehyde
#12
Marsha Sintara, Lin Li, David G Cunningham, Ronald L Prior, Xianli Wu, Tony Chang
American cranberry (Vaccinium macrocarpon) is native to Eastern North America. Recent studies have suggested that the A-type proanthocyanidins (PACs) in cranberries are effective in preventing urinary tract infection. To meet the growing interest in the cranberry market, an accurate, reliable, and simple method to determine PAC concentration is needed. In this study, a modified method using 4-dimethylaminocinnamaldehyde to quantify total PACs in cranberry products was validated. Cranberry juice extract powder, cranberry capsules containing juice extract, and cranberry juice concentrate were used as the samples in this study...
October 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28973819/phytochemical-compounds-and-antioxidant-activity-in-different-cultivars-of-cranberry-vaccinium-macrocarpon-l
#13
Jan Oszmiański, Joanna Kolniak-Ostek, Sabina Lachowicz, Józef Gorzelany, Natalia Matłok
Cranberries can be a component of a healthy diet, because they are a great source of health-promoting compounds and nutrients. The aims of this study were to evaluated phytochemicals and antioxidant activity in 6 cultivars of cranberry fruit grown in Poland. The content of polyphenols, carotenoids, chlorophylls, and triterpenoids were determined with the use of UPLC-PDA-MS/MS, although antioxidant activity was examined with DPPH, ABTS, and FRAP assays. The cvs. "Franklin," "Howes," and "Stevens" were characterized by the highest concentration of total polyphenols (4219, 3995, and 3584 mg/100 g dm), triterpenoids (3582, 3671, and 3451 mg/kg dm), carotenoids (9...
October 3, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28968554/quality-evaluation-of-low-fat-bologna-type-meat-product-with-a-nutritional-profile-designed-for-the-elderly
#14
Elizabeth Reyes-Padilla, Martín Valenzuela-Melendres, Juan Pedro Camou, Joseph G Sebranek, Heliodoro Alemán-Mateo, José Luis Dávila-Ramírez, German Cumplido-Barbeitia, Humberto González-Ríos
The objective of this work was to evaluate the quality of a bologna-type meat product designed for the elderly. Treatments were: control, without addition of cranberries (C), prunes (P), pecan nuts (N) or flaxseed (F); NP, with 5% N+5% P; FC, with 5% F+5% C; NC, with 5% N+5% C; FP, with 5% F+5% P. These formulations resulted in a product with high protein, low SFA and high antioxidant activity. Treatments with pecan nuts had higher MUFA while those with flaxseed had higher polyunsaturated fatty acids (PUFA)...
January 2018: Meat Science
https://www.readbyqxmd.com/read/28950214/advantages-of-a-validated-uplc-ms-ms-standard-addition-method-for-the-quantification-of-a-type-dimeric-and-trimeric-proanthocyanidins-in-cranberry-extracts-in-comparison-with-well-known-quantification-methods
#15
Ines van Dooren, Kenn Foubert, Mart Theunis, Tania Naessens, Luc Pieters, Sandra Apers
The berries of Vaccinium macrocarpon, cranberry, are widely used for the prevention of urinary tract infections. This species contains A-type proanthocyanidins (PACs), which intervene in the initial phase of the development of urinary tract infections by preventing the adherence of Escherichia coli by their P-type fimbriae to uroepithelial cells. Unfortunately, the existing clinical studies used different cranberry preparations, which were poorly standardized. Because of this, the results were hard to compare, which led sometimes to conflicting results...
September 9, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28946297/drying-induced-physico-chemical-changes-in-cranberry-products
#16
Anna Michalska, Aneta Wojdyło, Joanna Honke, Ewa Ciska, Wilfried Andlauer
Sugar-free cranberry juice (XAD) and juice with 15% of maltodextrin were dried by freeze-, vacuum and spray drying methods. Total phenolics (589-6435mg/kg dry matter) including 5 flavonols, 3 phenolic acids, 2 procyanidins and 5 anthocyanins were stronger affected by juice formulation than by drying methods. Spray drying of juice, regardless of its formulation, was competitive to freeze drying in terms of polyphenols' retention. Increase in temperature up to 100°C during vacuum drying of XAD extracts resulted in degradation of polyphenolics (down to 4%), except chlorogenic acid...
February 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28944014/honey-bee-collected-pollen-in-agro-ecosystems-reveals-diet-diversity-diet-quality-and-pesticide-exposure
#17
Megan J Colwell, Geoffrey R Williams, Rodger C Evans, Dave Shutler
European honey bees Apis mellifera are important commercial pollinators that have suffered greater than normal overwintering losses since 2007 in North America and Europe. Contributing factors likely include a combination of parasites, pesticides, and poor nutrition. We examined diet diversity, diet nutritional quality, and pesticides in honey bee-collected pollen from commercial colonies in the Canadian Maritime Provinces in spring and summer 2011. We sampled pollen collected by honey bees at colonies in four site types: apple orchards, blueberry fields, cranberry bogs, and fallow fields...
September 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28941672/phenolic-composition-and-antioxidant-potential-of-grain-legume-seeds-a-review
#18
REVIEW
Balwinder Singh, Jatinder Pal Singh, Amritpal Kaur, Narpinder Singh
Legumes are a good source of bioactive phenolic compounds which play significant roles in many physiological as well as metabolic processes. Phenolic acids, flavonoids and condensed tannins are the primary phenolic compounds that are present in legume seeds. Majority of the phenolic compounds are present in the legume seed coats. The seed coat of legume seeds primarily contains phenolic acids and flavonoids (mainly catechins and procyanidins). Gallic and protocatechuic acids are common in kidney bean and mung bean...
November 2017: Food Research International
https://www.readbyqxmd.com/read/28935065/no-250-recurrent-urinary-tract-infection
#19
Annette Epp, Annick Larochelle
OBJECTIVE: To provide an update of the definition, epidemiology, clinical presentation, investigation, treatment, and prevention of recurrent urinary tract infections in women. OPTIONS: Continuous antibiotic prophylaxis, post-coital antibiotic prophylaxis, and acute self-treatment are all efficient alternatives to prevent recurrent urinary tract infection. Vaginal estrogen and cranberry juice can also be effective prophylaxis alternatives. EVIDENCE: A search of PubMed and The Cochrane Library for articles published in English identified the most relevant literature...
October 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28924329/a-computational-tool-for-accelerated-analysis-of-oligomeric-proanthocyanidins-in-plants
#20
Mengliang Zhang, Jianghao Sun, Pei Chen
A computational tool was developed to facilitate proanthocyanidin analysis using data collected by ultra-high-performance liquid chromatography-diode array detection-high resolution accurate mass-mass spectrometry (UHPLC-DAD-HRAM-MS). Both identification and semi-quantitation of proanthocyanidins can be achieved by the developed computational tool. It can extract proanthocyanidin chromatographic peaks, deconvolute the isotopic patterns of A-type, B-type, and multi-charged proanthocyanidins ions, and predict proanthocyanidin structures...
March 2017: Journal of Food Composition and Analysis
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