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https://www.readbyqxmd.com/read/27898456/the-role-of-nonantibiotic-treatment-of-community-acquired-urinary-tract-infections
#1
Elisabetta Costantini, Konstantinos Giannitsas, Ester Illiano
PURPOSE OF REVIEW: To summarize evidence on the efficacy of nonantibiotic treatments in the prevention of recurrent urinary tract infections (UTIs). The need for antibiotic-free regimens seems to be imperative given the worldwide rates of resistance of uropathogens to available antibiotics. RECENT FINDINGS: In the recently published literature, cranberry products and probiotics are the focus of research. They both seem to be effective in preventing recurrent UTIs compared with placebo, but their benefit becomes less clear when they are compared with antibiotics...
November 24, 2016: Current Opinion in Urology
https://www.readbyqxmd.com/read/27889156/survival-of-hepatitis-a-virus-and-aichi-virus-in-cranberry-based-juices-at-refrigeration-4%C3%A2-%C3%A2-c
#2
Snigdha Sewlikar, Doris H D'Souza
Viral foodborne illness continues to be a health-concern globally, with numerous fruit and juice outbreaks of Hepatitis A virus (HAV) reported worldwide. Aichi virus (AiV) is an emerging pathogen with limited epidemiological data. Both, HAV and AiV are resistant to low pH and can survive under adverse environmental conditions leading to transmission ease. The objective of this study was to evaluate the survival of HAV and AiV in commercially-available cranberry-based juices (Cranberry juice cocktail, CJ and a 100% juice with cranberry, MJ) over 21 days at refrigeration (4 °C)...
April 2017: Food Microbiology
https://www.readbyqxmd.com/read/27866177/cranberries-for-preventing-recurrent-urinary-tract-infections-in-uncircumcised-boys
#3
Kong-Sang Wan, Chih-Kuang Liu, Wen-Kai Lee, Ming-Chung Ko, Che-Sheng Huang
Background • Highly concentrated cranberry juice has long been considered to have protective properties against urinary tract infections (UTIs), on the basis of its content of cranberry proanthocyanidins, with A-type interflavan bonds. Objective • This study intended to evaluate the benefits of a highly concentrated cranberry juice for the prevention of repeated episodes of UTI in uncircumcised boys. Design • The study was a randomized, controlled trial. Setting • The study took place at Taipei City Hospital, Renai and Zhongxing Branches (Taipei City, Taiwan)...
November 2016: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/27843960/addition-of-cranberry-to-proton-pump-inhibitor-based-triple-therapy-for-helicobacter-pylori-eradication
#4
Mohammadreza Seyyedmajidi, Anahita Ahmadi, Shahin Hajiebrahimi, Seyedali Seyedmajidi, Majid Rajabikashani, Mona Firoozabadi, Jamshid Vafaeimanesh
OBJECTIVE: Proton pump inhibitor-based triple therapy with two antibiotics for Helicobacter pylori eradication is widely accepted, but this combination fails in a considerable number of cases. Some studies have shown that cranberry inhibits the adhesion of a wide range of microbial pathogens, including H. pylori. The aim of this study was to assess the effect of cranberry on H. pylori eradication with a standard therapy including lansoprazole, clarithromycin, and amoxicillin (LCA) in patients with peptic ulcer disease (PUD)...
October 2016: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/27833172/cranberry-intervention-in-patients-with-prostate-cancer-prior-to-radical-prostatectomy-clinical-pathological-and-laboratory-findings
#5
Vladimir Student, Ales Vidlar, Jan Bouchal, Jana Vrbkova, Zdenek Kolar, Milan Kral, Pavel Kosina, Jitka Vostalova
BACKGROUND AND OBJECTIVES: Recently, we described an inverse association between cranberry supplementation and serum prostate specific antigen (PSA) in patients with negative biopsy for prostate cancer (PCa) and chronic nonbacterial prostatitis. This double blind placebo controlled study evaluates the effects of cranberry consumption on PSA values and other markers in men with PCa before radical prostatectomy. METHODS: Prior to surgery, 64 patients with prostate cancer were randomized to a cranberry or placebo group...
November 10, 2016: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/27799145/cranberry-capsules-do-not-reduce-urinary-tract-infections-in-older-women-study-finds
#6
Susan Mayor
No abstract text is available yet for this article.
October 30, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27787564/effect-of-cranberry-capsules-on-bacteriuria-plus-pyuria-among-older-women-in-nursing-homes-a-randomized-clinical-trial
#7
Manisha Juthani-Mehta, Peter H Van Ness, Luann Bianco, Andrea Rink, Sabina Rubeck, Sandra Ginter, Stephanie Argraves, Peter Charpentier, Denise Acampora, Mark Trentalange, Vincent Quagliarello, Peter Peduzzi
Importance: Bacteriuria plus pyuria is highly prevalent among older women living in nursing homes. Cranberry capsules are an understudied, nonantimicrobial prevention strategy used in this population. Objective: To test the effect of 2 oral cranberry capsules once a day on presence of bacteriuria plus pyuria among women residing in nursing homes. Design, Setting, and Participants: Double-blind, randomized, placebo-controlled efficacy trial with stratification by nursing home and involving 185 English-speaking women aged 65 years or older, with or without bacteriuria plus pyuria at baseline, residing in 21 nursing homes located within 50 miles (80 km) of New Haven, Connecticut (August 24, 2012-October 26, 2015)...
November 8, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27787544/cranberry-for-prevention-of-urinary-tract-infection-time-to-move-on
#8
EDITORIAL
Lindsay E Nicolle
No abstract text is available yet for this article.
November 8, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27778523/the-multifunctionality-of-berries-toward-blood-platelets-and-the-role-of-berry-phenolics-in-cardiovascular-disorders
#9
Beata Olas
Diet and nutrition have an important influence on the prophylaxis and progression of cardiovascular disease; one example is the inhibition of blood platelet functions by specific components of fruits and vegetables. Garlic, onion, ginger, dark chocolate and polyunsaturated fatty acids all reduce blood platelet aggregation. A number of fruits contain a range of cardioprotective antioxidants and vitamins, together with a large number of non-nutrient phytochemicals such as phenolic compounds, which may possess both antioxidant properties and anti-platelet activity...
October 25, 2016: Platelets
https://www.readbyqxmd.com/read/27774898/medicinal-plants-with-multiple-effects-on-cardiovascular-diseases-a-systematic-review
#10
Hojjat Rouhi-Boroujeni, Esfandiar Heidarian, Hamid Rouhi-Boroujeni, Fatemeh Deris, Mahmoud Rafieian-Kopaei
INTRODUCTION: Hyperlipidemia, obesity, hypertension, and diabetes are the most important risk factors for cardiovascular diseases. The aim of this systematic review article is to introduce the medicinal plants that exert significant clinical effects on hypertension, hyperlipidemia, obesity, and diabetes. METHODS: In this review article, the international research databases including MEDLINE, Google scholar, EBSCO, Academic Search, Web of Science, SciVerse, Scopus (SCOPUS), EBSCO, Academic Search, Cochrane, Central Register of Controlled Trials (CENTRAL) and a Chinese database (China Network Knowledge Infrastructure [CNKI]) were searched using the key words hyperlipidemia, hypertension, diabetes, herbal, obesity, and phytomedicine, matched by MESH, from their respective inceptions up to March, 2016...
October 21, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27754657/demonstrating-a-nutritional-advantage-to-the-fast-cooking-dry-bean-phaseolus-vulgaris-l
#11
Jason A Wiesinger, Karen A Cichy, Raymond P Glahn, Michael A Grusak, Mark A Brick, Henry J Thompson, Elad Tako
Dry beans (Phaseolus vulgaris L.) are a nutrient dense food rich in protein and micronutrients. Despite their nutritional benefits, long cooking times limit the consumption of dry beans worldwide, especially in nations where fuelwood for cooking is often expensive or scarce. This study evaluated the nutritive value of 12 dry edible bean lines that vary for cooking time (20 to 89 min) from four market classes (yellow, cranberry, light red kidney, and red mottled) of economic importance in bean consuming regions of Africa and the Americas...
October 18, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27739084/multidimensional-comparative-analysis-of-phenolic-compounds-in-organic-juices-with-high-antioxidant-capacity
#12
Dariusz Nowak, Michał Gośliński, Artur Szwengiel
BACKGROUND: A diet rich in fruit, vegetables and juices is associated with health benefit and reduced risk of certain civilization diseases. Antioxidant properties depend mainly on the total content of polyphenols and their composition. The aim of this study was to perform a multidimensional comparative analysis of phenolic compounds of organic juices with high antioxidant capacity (chokeberry, elderberry, cranberry, pomegranate). RESULTS: All the analyzed juices were a rich source of phenolic compounds...
October 14, 2016: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/27719908/effect-of-ultrasound-followed-by-high-pressure-processing-on-prebiotic-cranberry-juice
#13
Wesley Faria Gomes, Brijesh Kumar Tiwari, Óscar Rodriguez, Edy Sousa de Brito, Fabiano André Narciso Fernandes, Sueli Rodrigues
This work evaluated the effect of high pressure processing (HPP) and ultrasound (US) on the quality of prebiotic cranberry juice fortified with fructo-oligosaccharides (FOS). The juice was subjected to HPP for 5min (450MPa) and to ultrasonic treatment for 5min (600 and 1200W/L) followed by HPP for 5min (450MPa). Chemical analyses were carried out to identify and quantify the anthocyanins, and to quantify FOS, organic acids, instrumental color, soluble solids, pH and antioxidant capacity. Both non-thermal treatments preserved the FOS content maintaining the prebiotic property of the juice...
March 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27711848/metabolism-and-growth-inhibitory-activity-of-cranberry-derived-flavonoids-in-bladder-cancer-cells
#14
Jeevan K Prasain, Rajani Rajbhandari, Adam B Keeton, Gary A Piazza, Stephen Barnes
In the present study, anti-proliferative activities of cranberry derived flavonoids and some of their in vivo metabolites were evaluated using a panel of human bladder tumor cell lines (RT4, SCABER, and SW-780) and non-tumorigenic immortalized human uroepithelial cells (SV-HUC). Among the compounds tested, quercetin 3-O-glucoside, isorhamnetin (3'-O-methylquercetin), myricetin and quercetin showed strong concentration-dependent cell growth inhibitory activities in bladder cancer cells with IC50 values in a range of 8-92 μM...
September 14, 2016: Food & Function
https://www.readbyqxmd.com/read/27696537/expression-modulation-and-clinical-correlates-of-the-autophagy-protein-beclin-1-in-esophageal-adenocarcinoma
#15
Katherine M Weh, Amy B Howell, Laura A Kresty
Esophageal adenocarcinoma (EAC) is characterized by rapidly increasing incidence and mortality rates and poor survival. Efficacious preventive and treatment options are urgently needed. An increasing number of pharmacologic agents targeting cancer cell death via autophagy mechanisms are being evaluated in hopes of circumventing apoptotic and therapeutic resistance. We report for the first time, loss of Beclin-1, a key mediator of autophagy, was significantly linked to prognostic factors in EAC. Specifically, Beclin-1 expression loss occurred in 49...
November 2016: Molecular Carcinogenesis
https://www.readbyqxmd.com/read/27690414/urinary-clearance-of-cranberry-flavonol-glycosides-in-humans
#16
Yifei Wang, Ajay P Singh, Heather N Nelson, Amanda J Kaiser, Nicolette C Reker, Tisha L Hooks, Ted Wilson, Nicholi Vorsa
Cranberry is reported to have health benefits including prevention of urinary tract infections and other chronic diseases, due to the high content of polyphenols including flavonols and flavan-3-ols. The aim of this study was to determine the clearance of flavonol glycosides and flavan-3-ols and/or their metabolites in human urine. Ten healthy women volunteers ingested 240 ml cranberry juice containing flavonol glycosides. Urine samples were collected at 0, 90, 225 and 360 minutes post-ingestion. While flavan-3-ols were not detected, five flavonol glycosides common in cranberry were identified...
October 3, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27677719/botanicals-and-their-bioactive-phytochemicals-for-women-s-health
#17
Birgit M Dietz, Atieh Hajirahimkhan, Tareisha L Dunlap, Judy L Bolton
Botanical dietary supplements are increasingly popular for women's health, particularly for older women. The specific botanicals women take vary as a function of age. Younger women will use botanicals for urinary tract infections, especially Vaccinium macrocarpon (cranberry), where there is evidence for efficacy. Botanical dietary supplements for premenstrual syndrome (PMS) are less commonly used, and rigorous clinical trials have not been done. Some examples include Vitex agnus-castus (chasteberry), Angelica sinensis (dong quai), Viburnum opulus/prunifolium (cramp bark and black haw), and Zingiber officinale (ginger)...
October 2016: Pharmacological Reviews
https://www.readbyqxmd.com/read/27664641/electroanalytical-tools-for-antioxidant-evaluation-of-red-fruits-dry-extracts
#18
Isaac Yves Lopes de Macêdo, Luane Ferreira Garcia, Jerônimo Raimundo Oliveira Neto, Karla Carneiro de Siqueira Leite, Valdir Souza Ferreira, Paulo César Ghedini, Eric de Souza Gil
Red fruits are rich sources of antioxidant compounds with recognized health benefits. Since they are perishable, dried extracts emerge as more durable products and their quality control must include antioxidant capacity assays. In this study, the redox behavior of commercial dried products obtained from camu-camu, açai, acerola and cranberry red fruits was evaluated by electroanalytical approaches. The antioxidant potential was determined by 2,2-diphenyl-1-picrylhydrazyl free radical assay and the electrochemical index concept...
February 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27625778/anthocyanin-analyses-of-vaccinium-fruit-dietary-supplements
#19
Jungmin Lee
Vaccinium fruit ingredients within dietary supplements were identified by comparisons with anthocyanin analyses of known Vaccinium profiles (demonstration of anthocyanin fingerprinting). Available Vaccinium supplements were purchased and analyzed, their anthocyanin profiles (based on high-performance liquid chromatography [HPLC] separation) indicated if products' fruit origin listings were authentic. Over 30% of the Vaccinium fruit (cranberry, lingonberry, bilberry, and blueberry; 14 of 45) products available as dietary supplements did not contain the fruit listed as ingredients...
September 2016: Food Science & Nutrition
https://www.readbyqxmd.com/read/27619543/cranberry-extract-attenuates-hepatic-inflammation-in-high-fat-fed-obese-mice
#20
Shannon L Glisan, Caroline Ryan, Andrew P Neilson, Joshua D Lambert
Cranberry (Vaccinium macrocarpon) consumption has been associated with health beneficial effects. Nonalcoholic fatty liver disease (NAFLD) is a comorbidity of obesity. In the present study, we investigated the effect of a polyphenol-rich cranberry extract (CBE) on hepatic inflammation in high fat (HF)-fed obese C57BL/6J mice. Following dietary treatment with 0.8% CBE for 10 weeks, we observed no change in body weight or visceral fat mass in CBE-supplemented mice compared to HF-fed control mice. We did observe a significant decrease in plasma alanine aminotransferase (31%) and histological severity of NAFLD (33% decrease in area of involvement, 29% decrease in lipid droplet size) compared to HF-fed controls...
August 4, 2016: Journal of Nutritional Biochemistry
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