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https://www.readbyqxmd.com/read/28190352/polyphenol-interactions-mitigate-the-immunogenicity-and-allergenicity-of-gliadins
#1
Maxime Perot, Roberta Lupi, Sylvain Guyot, Carine Delayre-Orthez, Pascale Gadonna-Widehem, Jean-Yves Thebaudin, Marie Bodinier, Colette Larre
Wheat allergy is an IgE-mediated disorder. Polyphenols, which are known to interact with certain proteins, could be used to reduce allergic reactions. In this study, we screened several polyphenol sources for their ability to interact with gliadins, mask epitopes and impact basophil degranulation. Polyphenol extracts from artichoke leaves, cranberries, apples and green tea leaves were examined. Of these extracts, the first three formed insoluble complexes with gliadins. Only the cranberry and apple extracts masked epitopes in dot blot assays using anti-gliadin IgG and IgE antibodies from patients with wheat allergies...
February 13, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28186383/cranberry-capsules-to-prevent-nosocomial-urinary-tract-bacteriuria-after-pelvic-surgery-a-randomised-controlled-trial
#2
V Letouzey, D Ulrich, C Demattei, S Alonso, S Huberlant, J-P Lavigne, R de Tayrac
OBJECTIVE: To evaluate whether cranberries are able to prevent postoperative urinary bacteriuria in patients undergoing pelvic surgery and receiving transurethral catheterisation. DESIGN: Randomised, double-blind, placebo-controlled trial. SETTINGS: French tertiary Care centre, University Hospital. POPULATION: A total of 272 women undergoing pelvic surgery aged 18 or older. METHODS: Participants undergoing pelvic surgery were randomised to 36 mg cranberry (proanthocyanidins, PAC) or placebo once daily for 10 days...
February 10, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28165546/highly-standardized-cranberry-extract-supplementation-anthocran%C3%A2-as-prophylaxis-in-young-healthy-subjects-with-recurrent-urinary-tract-infections
#3
A Ledda, G Belcaro, M Dugall, A Riva, S Togni, R Eggenhoffner, L Giacomelli
OBJECTIVE: Several studies have investigated the role of cranberry extract in the prevention of recurrent urinary tract infections (UTIs), on different selected subpopulations at increased risk of UTI. In this registry, we tested the prophylactic effects of an oral supplementation containing a highly standardized cranberry extract (Anthocran®) in young subjects with a previous history of recurrent UTIs, over a 2-months follow-up. PATIENTS AND METHODS: 36 otherwise healthy subjects in juvenile age (between 12 and 18 years of age) suffering by recurrent UTIs were enrolled...
January 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28161211/cranberry-extract-inhibits-in-vitro-adhesion-of-f4-and-f18-escherichia-coli-to-pig-intestinal-epithelium-and-reduces-in-vivo-excretion-of-pigs-orally-challenged-with-f18-verotoxigenic-e-coli
#4
Annelies Coddens, Michaela Loos, Daisy Vanrompay, Jean Paul Remon, Eric Cox
F4(+)E. coli and F18(+)E. coli infections are an important threat for pig industry worldwide. Antibiotics are commonly used to treat infected piglets, but the emerging development of resistance against antibiotics raises major concerns. Hence, alternative therapies to prevent pigs from F4(+)E. coli and F18(+)E. coli infections need to be developed. Since cranberry previously showed anti-adhesive activity against uropathogenic E. coli, we aimed to investigate whether cranberry extract could also inhibit binding of F4(+)E...
January 20, 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28157162/evidence%C3%A2-of%C3%A2-some%C3%A2-natural%C3%A2-products%C3%A2-with%C3%A2-antigenotoxic%C3%A2-effects-%C3%A2-part%C3%A2-1-%C3%A2-fruits%C3%A2-and%C3%A2-polysaccharides
#5
REVIEW
Jeannett Alejandra Izquierdo-Vega, José Antonio Morales-González, Manuel SánchezGutiérrez, Gabriel Betanzos-Cabrera, Sara M Sosa-Delgado, María Teresa Sumaya-Martínez, Ángel Morales-González, Rogelio Paniagua-Pérez, Eduardo Madrigal-Bujaidar, Eduardo Madrigal-Santillán
Cancer is one of the leading causes of deaths worldwide. The agents capable of causing damage to genetic material are known  as genotoxins and, according to their mode of action, are classified into mutagens, carcinogens or teratogens. Genotoxins are  involved in the pathogenesis of several chronic degenerative diseases including hepatic, neurodegenerative and cardiovascular  disorders, diabetes, arthritis, cancer, chronic inflammation and ageing. In recent decades, researchers have found novel bioactive  phytocompounds able to counteract the effects of physical and chemical mutagens...
February 2, 2017: Nutrients
https://www.readbyqxmd.com/read/28151514/-cranberry-juice-and-urinary-tract-infections
#6
A Cura Della Redazione
No abstract text is available yet for this article.
October 2016: Assistenza Infermieristica e Ricerca: AIR
https://www.readbyqxmd.com/read/28144131/cranberry-juice-concentrate-does-not-significantly-decrease-the-incidence-of-acquired-bacteriuria-in-female-hip-fracture-patients-receiving-urine-catheter-a-double-blind-randomized-trial
#7
Anna-Karin Gunnarsson, Lena Gunningberg, Sune Larsson, Kenneth B Jonsson
BACKGROUND: Urinary tract infection (UTI) is a common complication among patients with hip fractures. Receiving an indwelling urinary catheter is a risk factor for developing UTIs. Treatment of symptomatic UTIs with antibiotics is expensive and can result in the development of antimicrobial resistance. Cranberries are thought to prevent UTI. There is no previous research on this potential effect in patients with hip fracture who receive urinary catheters. AIM: The aim of this study is to investigate whether intake of cranberry juice concentrate pre-operatively decreases the incidence of postoperative UTIs in hip fracture patients that received a urinary catheter...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28130087/sensory-perception-of-and-salivary-protein-response-to-astringency-as-a-function-of-the-6-n-propylthioural-prop-bitter-taste-phenotype
#8
Melania Melis, Neeta Y Yousaf, Mitchell Z Mattes, Tiziana Cabras, Irene Messana, Roberto Crnjar, Iole Tomassini Barbarossa, Beverly J Tepper
Individual differences in astringency perception are poorly understood. Astringency from tannins stimulates the release of specific classes of salivary proteins. These proteins form complexes with tannins, altering their perceived astringency and reducing their bioavailability. We studied the bitter compound, 6-n-propylthioural (PROP), as a phenotypic marker for variation in astringency perception and salivary protein responses. Seventy-nine subjects classified by PROP taster status rated cranberry juice cocktail (CJC; with added sugar) supplemented with 0, 1...
January 24, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28100853/antioxidant-and-antimicrobial-properties-of-bioactive-phytochemicals-from-cranberry
#9
Monika Baranowska, Agnieszka Bartoszek
In the rational human diet, the important role of fruits and vegetables, which are a source of bioactive phytochemicals, is emphasized. Among fruits particular attention, due to a number of documented health-promoting properties, is focused on cranberry. This fruit is characterized by the high content of antioxidant phenolic compounds, which may support the natural antioxidant defense system of the body in the prevention of damage caused by oxidative stress induced by reactive oxygen species (ROS). Therefore, cranberry is suggested for the prevention of civilization diseases such as atherosclerosis, hypertension and cancer, whose etiology is associated directly with oxidative stress...
December 31, 2016: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/28070326/effects-of-cranberry-extracts-on-gene-expression-in-thp-1-cells
#10
Daniel B Hannon, Jerry T Thompson, Christina Khoo, Vijaya Juturu, John P Vanden Heuvel
Cranberry contains high levels of nutrients and bioactive molecules that have health-promoting properties. The purpose of the present studies was to determine if cranberry extracts (CEs) contain phytochemicals that exert anti-inflammatory effects. The human monocytic cell line THP-1 was treated with two CEs (CE and 90MX) and subsequently challenged with Lipopolysaccharides (LPS). Tumor necrosis factor α (TNF α) expression was decreased in the CE-treated cells, indicative of an anti-inflammatory effect. Gene expression microarrays identified several immune-related genes that were responsive to CEs including interferon-induced protein with tetratricopeptide repeats 1 and 3 (IFIT 1 and 3), macrophage scavenger receptor 1 (MSR1) and colony-stimulating factor 2 (CSF2)...
January 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28065420/effectiveness-of-dietary-supplements-in-spinal-cord-injury-subjects
#11
REVIEW
Angela Navarrete-Opazo, Pilar Cuitiño, Inés Salas
BACKGROUND: Individuals with spinal cord injury (SCI) consume more dietary supplements than the general population. However, there is limited information regarding the clinical effectiveness of dietary supplements in SCI population. OBJECTIVE: To systematically review the effectiveness of dietary supplements for the prevention or treatment of health-related conditions associated with SCI. METHODS: Randomized or non-randomized controlled clinical trials were selected, comparing the effect of any dose and form of a dietary supplement (defined by the Dietary Supplement Health and Education Act), with either no treatment, placebo, or other medication...
December 19, 2016: Disability and Health Journal
https://www.readbyqxmd.com/read/28051247/supplementation-with-high-titer-cranberry-extract-anthocran%C3%A2-for-the-prevention-of-recurrent-urinary-tract-infections-in-elderly-men-suffering-from-moderate-prostatic-hyperplasia-a-pilot-study
#12
A Ledda, G Belcaro, M Dugall, B Feragalli, A Riva, S Togni, L Giacomelli
OBJECTIVE: Recently, cranberry extracts have been tested as a nutritional supplementation in the prevention of lower urinary tract symptoms (LUTS) as well as recurrent urinary tract infections (UTIs) in subjects at risk, with mixed results. However, evidence of efficacy should be considered only for well-characterized and standardized products in a more selected study population. Moreover, the efficacy of these interventions in elderly must be further investigated. The aim of this pilot, registry study was to evaluate the prophylactic effects of an oral supplementation containing a highly concentrated and standardized cranberry extract reproducing the natural total profile of cranberry fruits, in elderly men with benign prostatic hyperplasia (BPH), suffering from recurrent UTIs, over a 2-months follow-up...
December 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28034861/dtb-select-1-january-2017
#13
(no author information available yet)
Brimonidine gel: risk of exacerbation of rosacea ● Metformin for patients with moderately reduced kidney function ● Effect of an optimal cranberry dose on bacteriuria ● Amitriptyline and topiramate ineffective for paediatric migraine prophylaxis ● Etoricoxib: 60mg dose for RA and ankylosing spondylitis ● CRP and diagnosis of CAP ● International travel and antimicrobial resistance ● Effect of telemedicine on diabetes control.
December 29, 2016: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28012791/aromatic-profile-and-sensory-characterisation-of-ultrasound-treated-cranberry-juice-and-nectar
#14
Anet Režek Jambrak, Marina Šimunek, Marinko Petrović, Helena Bedić, Zoran Herceg, Hrvoje Juretić
Ultrasonication is a nonthermal food processing technology that is used in several applications (extraction, pretreatment before drying, freezing, inactivation of microorganisms etc.). The objective of this study was to investigate the effect of high power ultrasound and pasteurisation on the aroma profile and sensory properties of cranberry juice and nectar. Samples were treated according to the experimental design, with high power sonicator at ultrasound frequency of 20kHz under various conditions (treatment time 3, 6 and 9min, sample temperature: 20, 40 and 60°C and amplitude 60, 90 and 120μm)...
November 25, 2016: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/27979205/characterization-classification-and-authentication-of-fruit-based-extracts-by-means-of-hplc-uv-chromatographic-fingerprints-polyphenolic-profiles-and-chemometric-methods
#15
Naiara Pardo-Mates, Alex Vera, Sergio Barbosa, Míriam Hidalgo-Serrano, Oscar Núñez, Javier Saurina, Santiago Hernández-Cassou, Lluis Puignou
HPLC-UV was applied to the analysis and characterization of fruit-based and fruit-processed products. A Kinetex C18 reversed-phase column was proposed under gradient elution for the determination of 17 polyphenols. Acceptable sensitivity (LODs below 0.16mg/L), and good linearity (r(2) higher than 0.995), precision (RSD below 6.8%), and method trueness (relative errors below 11%) were obtained. Data corresponding to polyphenolic peak areas and HPLC-UV chromatographic fingerprints were then analyzed by exploratory principal component analysis (PCA) to extract information of the most significant variables contributing to characterization and classification of analyzed samples regarding the fruit of origin...
April 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27979197/potential-health-benefits-and-quality-of-dried-fruits-goji-fruits-cranberries-and-raisins
#16
Magdalena Jeszka-Skowron, Agnieszka Zgoła-Grześkowiak, Ewa Stanisz, Agnieszka Waśkiewicz
Dried fruits are important snacks and additives to other foods due to their taste and nutritional advantages. Therefore there is an important goal to control the quality of the food on the market for consumer's safety. Antioxidant activity of goji fruits (Lycium barbarum), cranberries (Vaccinium macrocarpon and oxycoccus) and raisins (Vitis vinifera) were studied using the DPPH (2,2-diphenyl-1-picrylhydrazyl) and Folin-Ciocalteu assays. Cu, Mn and Ge influencing antioxidant activity were determined together with selected toxic metals (Cd, Ni and Pb)...
April 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27976244/solid-liquid-extraction-as-key-step-for-quality-assessment-of-commercial-cranberry-products-using-hptlc-densitometry
#17
L Boudesocque-Delaye, J Dorat, A Lanoue, E Ceniviva, F Bruyère, C Enguehard-Gueiffier
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27976148/innovative-bioguided-fractionation-of-cranberry-juice-for-candida-biofilm-treatment-and-infected-wound-healing
#18
L Boudesocque-Delaye, T Puy, M Girardot, A Lanoue, L Bazinet, C Bodet, C Imbert, C Enguehard-Gueiffier
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27960275/phenolics-of-selected-cranberry-genotypes-vaccinium-macrocarpon-ait-and-their-antioxidant-efficacy
#19
Gihan Abeywickrama, Samir C Debnath, Priyatharini Ambigaipalan, Fereidoon Shahidi
Free, esterified, and bound phenolic fractions of berries from five different cranberry genotypes and two market samples were evaluated for their total phenolic, flavonoid, and monomeric anthocyanin contents as well as their antioxidant efficacy using TEAC, ORAC, DPPH radical, reducing power, and ferrous ion chelation capacity assays. HPLC-MS/MS analysis was performed for two of the rich sources (Pilgrim and wild clone NL2) of phenolics and high antioxidant activity. Among the genotypes, Pilgrim showed the highest phenolic and flavonoid contents and wild clones NL3 and NL2 showed the highest monomeric anthocyanin and proanthocyanidin content, respectively...
December 14, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27937080/photoprotective-effects-of-cranberry-juice-and-its-various-fractions-against-blue-light-induced-impairment-in-human-retinal-pigment-epithelial-cells
#20
Chi-Huang Chang, Hui-Fang Chiu, Yi-Chun Han, I-Hsien Chen, You-Cheng Shen, Kamesh Venkatakrishnan, Chin-Kun Wang
CONTEXT: Cranberry has numerous biological activities, including antioxidation, anticancer, cardioprotection, as well as treatment of urinary tract infection (UTI), attributed to abundant phenolic contents. OBJECTIVE: The current study focused on the effect of cranberry juice (CJ) on blue light exposed human retinal pigment epithelial (ARPE-19) cells which mimic age-related macular degeneration (AMD). MATERIALS AND METHODS: Preliminary phytochemical and HPLC analysis, as well as total antioxidant capacity and scavenging activity of cranberry ethyl acetate extract and different CJ fractions (condensed tannins containing fraction), were evaluated...
December 2017: Pharmaceutical Biology
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