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Thyroid and coronary heart disease

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https://www.readbyqxmd.com/read/27926474/the-association-of-thyroid-function-and-the-risk-of-kidney-function-decline-a-population-based-cohort-study
#1
Layal Chaker, Sanaz Sedaghat, Ewout J Hoorn, Wendy P J Den Elzen, Jacobijn Gussekloo, Albert Hofman, M Arfan Ikram, Oscar H Franco, Abbas Dehghan, Robin P Peeters
OBJECTIVES: Thyroid dysfunction has been associated with kidney function decline, but mainly in cross-sectional studies. Therefore, we aimed to determine the association between thyroid and kidney function in a prospective population-based cohort study longitudinally. DESIGN: Prospective cohort study. METHODS: Participants aged ≥45 years from the Rotterdam Study with thyroid and kidney function assessment were included. Kidney function and new onset chronic kidney disease (CKD) were defined using estimated glomerular filtration ate (eGFR), with CKD defined as eGFR <60 mL/min/1...
December 2016: European Journal of Endocrinology
https://www.readbyqxmd.com/read/27913498/long-term-risk-of-second-malignancy-and-cardiovascular-disease-after-hodgkin-lymphoma-treatment
#2
Flora E van Leeuwen, Andrea K Ng
Long-term survivors of Hodgkin lymphoma (HL) experience several late adverse effects of treatment, with second malignant neoplasms (SMNs) and cardiovascular diseases (CVDs) being the leading causes of death in these patients. Other late effects have also been identified, such as pulmonary dysfunction, endocrinopathies (thyroid dysfunction, infertility), neck muscle atrophy, and persistent fatigue. HL survivors have two- to fourfold increased risks to develop SMNs and CVD compared with the general population...
December 2, 2016: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/27903390/-current-status-of-antiarrhythmic-drug-use-and-safety-assessment-in-chinese-patients-with-atrial-fibrillation
#3
R He, X Du, S W Liu, L J Sun, Y Li, H Zeng, Y Y Li, C Sun, Y Zhang, C S Ma, W Gao
Objective: To investigate the current status of antiarrhythmic drugs (AADs) use in Chinese patients with atrial fibrillation(AF) and assess the safety of AADs in this patient cohort. Methods: From January 2011 to December 2013, a total of 4 008 AF patients treated with AADs was enrolled in this study and patients were followed up for 24 months. Detailed information of prescribed drug, the causes of drug discontinuation and side effects were recorded. Results: Amiodarone was prescribed to 64.3%(2 579 cases) and propafenone to 31...
November 24, 2016: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/27886135/soy-and-health-update-evaluation-of-the-clinical-and-epidemiologic-literature
#4
REVIEW
Mark Messina
Soyfoods have long been recognized as sources of high-quality protein and healthful fat, but over the past 25 years these foods have been rigorously investigated for their role in chronic disease prevention and treatment. There is evidence, for example, that they reduce risk of coronary heart disease and breast and prostate cancer. In addition, soy alleviates hot flashes and may favorably affect renal function, alleviate depressive symptoms and improve skin health. Much of the focus on soyfoods is because they are uniquely-rich sources of isoflavones...
November 24, 2016: Nutrients
https://www.readbyqxmd.com/read/27849383/free-thyroid-hormones-and-mortality-in-caucasians-undergoing-angiography-the-ludwigshafen-risk-and-cardiovascular-health-luric-study
#5
Anette Merke, Jürgen Merke, Guenther Silbernagel, Winfried März
TITLE: Free Thyroid Hormones and Mortality in Caucasians undergoing Angiography: The LUdwigshafen RIsk and Cardiovascular Health Study (LURIC) Objective: Alterations in thyroid hormone functions are associated with mortality and morbidity. Data on euthyroid individuals are very limited and controversial. We therefore investigated the relationship between circulating thyroid hormones and all-cause and cardiovascular (CV) mortality in participants of the LURIC study and their association with morbidity...
November 16, 2016: Endocrine Practice
https://www.readbyqxmd.com/read/27776249/non-thyroidal-illness-syndrome-in-patients-with-cardiovascular-diseases-a-systematic-review-and-meta-analysis
#6
Bin Wang, Suijun Liu, Ling Li, Qiuming Yao, Ronghua Song, Xiaoqing Shao, Qian Li, Xiaohong Shi, Jin-An Zhang
BACKGROUND: Non-thyroidal illness syndrome (NTIS) is characterized by decreased serum triiodothyronine level without increased thyroid-stimulating hormone level during critical illness. The summary data on the prevalence of NTIS in cardiovascular patients are lacking, and its prognostic role in cardiovascular patients is also unclear. METHODS: We performed a systematic review and meta-analysis to comprehensively determine the prevalence and the prognostic role of NTIS in cardiovascular patients...
January 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27729057/takotsubo-like-syndrome-triggered-by-fludrocortisone-overdose-for-addison-s-disease-a-case-report
#7
Radu Campean, Matthias Hasun, Claudia Stöllberger, Johannes Bucher, Josef Finsterer, Christoph Schnack, Franz Weidinger
BACKGROUND: Reversible left ventricular dysfunction, also termed Takotsubo cardiomyopathy, is rarely reported in Addison's disease after initiation of hormone replacement therapy. The pathogenesis of this cardiomyopathy is unknown. CASE PRESENTATION: A 41-year-old white woman with a history of autoimmune Hashimoto thyroiditis diagnosed 3 years earlier and acute adrenal insufficiency diagnosed 3 weeks earlier presented with new onset of heart failure New York Heart Association class IV, which had started shortly after initiation of hormone replacement therapy with hydrocortisone 20 mg/day and fludrocortisone 0...
October 12, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27630135/lone-atrial-fibrillation-is-associated-with-impaired-left-ventricular-energetics-that-persists-despite-successful-catheter-ablation
#8
Rohan S Wijesurendra, Alexander Liu, Christian Eichhorn, Rina Ariga, Eylem Levelt, William T Clarke, Christopher T Rodgers, Theodoros D Karamitsos, Yaver Bashir, Matthew Ginks, Kim Rajappan, Tim Betts, Vanessa M Ferreira, Stefan Neubauer, Barbara Casadei
BACKGROUND: Lone atrial fibrillation (AF) may reflect a subclinical cardiomyopathy that persists after sinus rhythm (SR) restoration, providing a substrate for AF recurrence. To test this hypothesis, we investigated the effect of restoring SR by catheter ablation on left ventricular (LV) function and energetics in patients with AF but no significant comorbidities. METHODS: Fifty-three patients with symptomatic paroxysmal or persistent AF and without significant valvular disease, uncontrolled hypertension, coronary artery disease, uncontrolled thyroid disease, systemic inflammatory disease, diabetes mellitus, or obstructive sleep apnea (ie, lone AF) undergoing ablation and 25 matched control subjects in SR were investigated...
October 11, 2016: Circulation
https://www.readbyqxmd.com/read/27558484/recombinant-human-thyrotropin-improves-endothelial-coronary-flow-reserve-in-thyroidectomized-patients-with-differentiated-thyroid-cancer
#9
Serena Ippolito, Renato Ippolito, Carmela Peirce, Roberta Esposito, Debora Arpaia, Ciro Santoro, Gilda Pontieri, Sara Cocozza, Maurizio Galderisi, Bernadette Biondi
BACKGROUND: The role of thyrotropin (TSH) on the cardiovascular system has been poorly investigated. It is unknown whether the changes in the vasculature associated with thyroid diseases result from altered thyroid hormone action or whether they are a consequence of a direct effect of TSH on endothelial cells. The present study was designed to evaluate the endothelial response of coronary flow to TSH in patients with differentiated thyroid cancer (DTC) without cardiovascular risk factors...
October 14, 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27358549/combined-open-heart-coronary-artery-bypass-surgery-and-subtotal-thyroidectomy-in-a-54-year-old-patient-a-case-report
#10
Shahriar Mali, Mohammadtaghi Sarebanhassanabadi
BACKGROUND: Combined open-heart surgery and thyroidectomy is a rare procedure. However, some difficulties will occur for cardiac surgery when thyromegaly extends into the retrosternal space. CASE DETAILS: A 54-year-old woman suffering from dyspnea, chest pain and decreased left ventricular function (EF=40%) was diagnosed with coronary artery disease (3 vessel disease) and became candidate for coronary artery bypass grafting (CABG). Also, she had multinodular goiter with normal thyroid function test...
May 2016: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/27347890/thyroid-hormone-and-cardioprotection
#11
Anthony Martin Gerdes, Kaie Ojamaa
The heart is a major target of thyroid hormones, with maintenance of euthyroid hormone balance critical for proper function. In particular, chronic low thyroid function can eventually lead to dilated heart failure with impaired coronary blood flow. New evidence also suggests that heart diseases trigger a reduction in cardiac tissue thyroid hormone levels, a condition that may not be detectible using serum hormone assays. Many animal and clinical studies have demonstrated a high prevalence of low thyroid function in heart diseases with worse outcomes from this condition...
2016: Comprehensive Physiology
https://www.readbyqxmd.com/read/27263064/prognostic-impact-of-comorbidities-in-hospitalized-patients-with-acute-exacerbation-of-chronic-heart-failure
#12
Domenico Scrutinio, Andrea Passantino, Pietro Guida, Enrico Ammirati, Fabrizio Oliva, Simona Sarzi Braga, Maria Teresa La Rovere, Rocco Lagioia, Maria Frigerio
BACKGROUND: To assess the impact of comorbidities on long-term all-cause mortality in patients hospitalized with exacerbated signs/symptoms of previously chronic stable HF (AE-CHF). METHODS: 1119 patients admitted for AE-CHF and with NT-proBNP levels >900pg/mL were enrolled. Univariable and multivariable Cox analyses were performed to assess the association of age, gender, hypertension, diabetes, obesity, atrial fibrillation, coronary heart disease (CHD), chronic obstructive pulmonary disease, previous cerebrovascular accidents, chronic liver disease (CLD), thyroid disease, renal impairment (RI), and anemia with 3-year all-cause mortality...
June 1, 2016: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/27137820/-arrhythmia-device-interventions-and-mortality-analysis-in-patients-with-implanted-cardioverter-defibrillator-with-without-resynchronisation-therapy-in-dilative-cardiomyopathy-in-primary-prevention-of-sudden-cardiac-death
#13
Jacek Lelakowski, Joanna Pudło, Maria Lelakowska-Pieła, Anna Rydlewska, Justyna Piekarz, Donat Domaracki
UNLABELLED: Ambulatory follow-up of patients with implanted cardioverter-defibrillator (ICD) with/without resynchronisation therapy (CRTD) requires regular visits to assess arrhythmias, device interventions and mortality. AIM: The aim of the study was to examine arrhythmia prevalence, device interventions and mortality in patients with dilative cardiomyopathy with ICD/CRTD implanted in primary sudden cardiac death (SCD) prevention. MATERIALS AND METHODS: The study consisted of patients with ICD and/or CRTD implanted between 2010-2011...
April 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27111311/the-relationship-between-serum-thyroid-hormone-levels-subclinical-hypothyroidism-and-coronary-collateral-circulation-in-patients-with-stable-coronary-artery-disease
#14
Mehmet Ballı, Mustafa Çetin, Hakan Taşolar, Onur Kadir Uysal, Mahmut Yılmaz, Mine Durukan, Zafer Elbasan, Murat Çaylı
OBJECTIVE: Thyroid disease is a common endocrine disease with important effects on the cardiovascular system. As an adaptive response to myocardial ischemia, coronary collateral circulation (CCC) plays an important role in obstructive coronary artery disease (CAD). The association between serum thyroid hormone levels and development of CCC was investigated in the present study. METHODS: In total, 430 consecutive patients who underwent coronary angiography procedure and had documented total occlusion in at least 1 major coronary artery were investigated retrospectively...
March 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/27085207/blood-pressure-response-is-impaired-in-patients-with-exercise-induced-ventricular-ectopy
#15
Oguzhan Ekrem Turan, Mustafa Ozturk, Ibrahim Kocaoglu, Selen Gursoy Turan
Exercise-induced ventricular ectopy (EIVE) has clinical and prognostic significance. But the mechanism underlying EIVE-related mortality still remains unclear. This study aims to assess blood pressure alteration in patients with EIVE and to identify the potential causes of increased mortality in this patient group. A total number of 3611 patients were screened within a 1-year period, and patients with a structural heart disease, coronary artery disease, hypertension, diabetes mellitus, thyroid dysfunction, and chronic renal disease were excluded from the study...
May 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27052547/the-clinical-analysis-of-bilateral-successive-sudden-sensorineural-hearing-loss
#16
Yaowen Wang, Litao Zhang, Jianhua Zhang, Xuqun Zhang, Weimin Zhang, Xing Chen, Shixiong Tang
The objective of this study is to investigate the clinical characteristics of successive bilateral sudden sensorineural hearing loss (SSNHL) with an interval of more than 1 year to aid the evaluation and management of successive bilateral SSNHL (BSSNHL). 14 successive BSSNHL patients and 118 unilateral SSNHL patients with severe and profound hearing loss were reviewed retrospectively. Information about successive BSSNHL was collected included demographics, the intervals between the attacks of bilateral ears, the past medical history, inducing factors, accompanying symptoms, pure-tone tests, blood tests, b-ultrasound examinations of vertebral artery and carotid artery, and medical interventions...
November 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27011011/cardioprotection-and-thyroid-hormones
#17
Alessandro Pingitore, Giuseppina Nicolini, Claudia Kusmic, Giorgio Iervasi, Paolo Grigolini, Francesca Forini
The evolution of cardiac disease after an acute ischemic event depends on a complex and dynamic network of mechanisms alternating from ischemic damage due to acute coronary occlusion to reperfusion injury due to the adverse effects of coronary revascularization till post-ischemic remodeling. Cardioprotection is a new purpose of the therapeutic interventions in cardiology with the goal to reduce infarct size and thus prevent the progression toward heart failure after an acute ischemic event. In a complex biological system such as the human one, an effective cardioprotective strategy should diachronically target the network of cross-talking pathways underlying the disease progression...
July 2016: Heart Failure Reviews
https://www.readbyqxmd.com/read/27003842/perfluoroalkyl-substances-in-older-male-anglers-in-wisconsin
#18
Krista Y Christensen, Michelle Raymond, Brooke A Thompson, Henry A Anderson
BACKGROUND: Perfluoroalkyl substances (PFAS) are an emerging class of contaminants. Certain PFAS are regulated or voluntarily limited due to concern about environmental persistence and adverse health effects, including thyroid disease and to dyslipidemia. The major source of PFAS exposure in the general population is seafood. OBJECTIVES: In this analysis we examine PFAS levels and their determinants, as well as associations between PFAS levels and self-reported health outcomes, in a group of older male anglers in Wisconsin with high fish consumption...
May 2016: Environment International
https://www.readbyqxmd.com/read/26981865/safe-oral-triiodo-l-thyronine-therapy-protects-from-post-infarct-cardiac-dysfunction-and-arrhythmias-without-cardiovascular-adverse-effects
#19
Viswanathan Rajagopalan, Youhua Zhang, Kaie Ojamaa, Yue-Feng Chen, Alessandro Pingitore, Christine J Pol, Debra Saunders, Krithika Balasubramanian, Rheal A Towner, A Martin Gerdes
BACKGROUND: A large body of evidence suggests that thyroid hormones (THs) are beneficial for the treatment of cardiovascular disorders. We have shown that 3 days of triiodo-L-thyronine (T3) treatment in myocardial infarction (MI) rats increased left ventricular (LV) contractility and decreased myocyte apoptosis. However, no clinically translatable protocol is established for T3 treatment of ischemic heart disease. We hypothesized that low-dose oral T3 will offer safe therapeutic benefits in MI...
2016: PloS One
https://www.readbyqxmd.com/read/26927632/is-there-any-effect-on-smell-and-taste-functions-with-levothyroxine-treatment-in-subclinical-hypothyroidism
#20
Kamil Baskoy, Seyid Ahmet Ay, Aytug Altundag, Onuralp Kurt, Murat Salihoglu, Ferhat Deniz, Hakan Tekeli, Arif Yonem, Thomas Hummel
Subclinical hypothyroidism has been accused for coronary heart disease, lipid metabolism disorders, neuropsychiatric disorders, infertility or pregnancy related problems with various strength of evidence. Currently there is insufficient knowledge about olfaction and taste functions in subclinical hypothyroidism. Aim of the present study is to investigate the degree of smell and taste dysfunction in patients with subclinical hypothyroidism. 28 subclinical hypothyroid patients, and 31 controls enrolled in the prospective study in Istanbul, Turkey...
2016: PloS One
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