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https://www.readbyqxmd.com/read/28340508/dyspareunia-in-a-survivor-of-childhood-sexual-abuse
#1
Jenna A LoGiudice
Dyspareunia is a frequent chief concern encountered by midwives and other women's health care providers. There are many possible etiologies for dyspareunia, including a history of childhood sexual abuse, and approaching assessment in a holistic manner is necessary to identify the etiology. This case report presents evidence on the importance of screening a woman who presents with dyspareunia in a therapeutic manner to facilitate disclosure of sexual abuse. Best practices for screening for sexual violence, along with recommendations for providing gynecologic care to survivors, are offered...
March 24, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28340450/health-promotion-and-psychological-interventions-for-adolescent-and-young-adult-cancer-survivors-a-systematic-literature-review
#2
REVIEW
Natalie Katrina Bradford, Raymond Javan Chan
BACKGROUND: The effects of cancer and treatment have severe and long lasting negative impacts on quality of life. Adolescents and Young Adults (AYA) have high survival rates but may not reach their full life potential because of these consequences. This review aims to identify, appraise and synthesise the effects of health promotion and psychological interventions for AYA after cancer treatment. METHODS: The review was undertaken using the preferred reporting items for systematic reviews and meta-analyses guidelines...
March 6, 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28340081/retroocular-and-subdural-hemorrhage-or-hemosiderin-deposits-in-pediatric-autopsies
#3
Marc R Del Bigio, Susan M Phillips
The presence of hemosiderin in the optic nerve sheath and/or retina is sometimes used to estimate the timing of injury in infants or children with suspected non-accidental head trauma. To determine the prevalence of hemosiderin in deaths not associated with trauma, we performed a prospective study of retroocular orbital tissue, cranial convexity, and cervical spinal cord dura mater in infants and children <2.5 years age. In 53 cases of non-traumatic death, approximately 70% had blood or hemosiderin within the orbital fat, ocular muscles, and parasagittal cranial and/or cervical spinal subdural compartment...
March 14, 2017: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/28339955/procalcitonin-in-childhood-pneumonia
#4
Samir S Shah, Todd A Florin, Lilliam Ambroggio
No abstract text is available yet for this article.
March 2, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28339840/the-effects-of-sexual-orientation-on-the-relationship-between-victimization-experiences-and-smoking-status-among-us-women
#5
Alicia K Matthews, Young Ik Cho, Tonda L Hughes, Sharon C Wilsnack, Frances Aranda, Timothy Johnson
Introduction: This study examined the relationships between experiences of childhood and adulthood victimization and current smoking among heterosexual and sexual minority women (SMW). The main hypothesis was that victimization experiences would predict current smoking status. Further, we hypothesized that the effect of childhood victimization on self-reported smoker status would be mediated by adult victimization. Methods: Data are from two studies conducted in the United States that used similar methods and questionnaires in order to conduct a comparative analysis of women based on sexual orientation...
March 1, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28339727/rapid-decrease-in-rates-of-hospitalization-resulting-from-invasive-pneumococcal-disease-and-community-acquired-pneumonia-in-children-aged-60-months-after-13-valent-pneumococcal-conjugate-vaccine-introduction-in-argentina
#6
Eduardo L López, Eduardo Glatstein, Gustavo C Ezcurra, Marisa Iacono, Eduardo Teplitz, Analía V Garnero, Daniela L Lazzarini, Miryan Vázquez, María M Contrini
Background.: In January 2012, Argentina included universal pneumococcal vaccination in the routine childhood vaccination program using a 13-valent pneumococcal conjugate vaccine (PCV13). A 2 + 1 schedule (2 doses in the first year of life and a booster dose at 12 months of age) in children aged <2 years and 2-dose catch-up immunization in children aged 13 to 24 months was administered during the first year of vaccine introduction. The purpose of this study was to assess the burdens of invasive pneumococcal disease (IPD) and/or community-acquired pneumonia (CAP) in hospitalized children younger than 5 years during the first 2 years of the program compared to those in the prevaccination period in our setting...
February 23, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28339574/arm-paralysis-after-routine-childhood-vaccinations-application-of-advanced-molecular-methods-to-the-causality-assessment-of-an-adverse-event-after-immunization
#7
Jana Shaw, Neal A Halsey, Adriana Weinberg, D Scott Schmid, Kirsten St George, William C Weldon, Michael Jordan, Patrick W Bryant, Philip S LaRussa, Deborah Y Bradshaw, Theresa Harrington, Anne Gershon
Post-licensure surveillance for adverse events following immunizations (AEFI) can identify rare complications of vaccinations and rigorous vaccine adverse event causality assessments can help to identify possible causal relationships. We report the development of arm paralysis after varicella vaccination in a 1-year-old child. Paralysis was initially presumed to be due to vOka because of the temporal relationship between vaccination and onset of arm weakness; however, molecular studies identified wild-type varicella zoster virus VZV (WT-VZV) in the CSF, leading the authors to conclude that WT-VZV was the probable cause...
January 25, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28339469/non-invasive-evaluation-of-muscle-disease-in-the-canine-model-of-duchenne-muscular-dystrophy-by-electrical-impedance-myography
#8
Chady H Hakim, Alex Mijailovic, Thais B Lessa, Joan R Coates, Carmen Shin, Seward B Rutkove, Dongsheng Duan
Dystrophin-deficient dogs are by far the best available large animal models for Duchenne muscular dystrophy (DMD), the most common lethal childhood muscle degenerative disease. The use of the canine DMD model in basic disease mechanism research and translational studies will be greatly enhanced with the development of reliable outcome measures. Electrical impedance myography (EIM) is a non-invasive painless procedure that provides quantitative data relating to muscle composition and histology. EIM has been extensively used in neuromuscular disease research in both human patients and rodent models...
2017: PloS One
https://www.readbyqxmd.com/read/28339359/cardiac-involvement-as-a-presenting-feature-of-eosinophilic-granulomatosis-with-polyangiitis-in-childhood
#9
Timothy D Reynolds, Catherine Armstrong, Athimalaipet V Ramanan
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March 15, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28339338/fertility-treatments-among-female-cancer-survivors-giving-birth-a-finnish-register-based-study
#10
Johanna Melin, Laura Madanat-Harjuoja, Sirpa Heinävaara, Nea Malila, Mika Gissler, Aila Tiitinen
BACKGROUND: Long-term survival rates for most types of childhood cancers have improved dramatically over the past decades. However, because of advances in multimodality treatments, cancer survivors nowadays more often face long-term complications, including diminished gonadal and reproductive function. The aim of this study was to identify whether the use of fertility treatments among early onset (0-34 years) cancer survivors giving birth differed from that among siblings giving birth and to identify the subgroups of cancer survivors that were most likely to require fertility treatments...
March 24, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28339329/morbidity-and-mortality-associated-with-meningioma-after-cranial-radiotherapy-a-report-from-the-childhood-cancer-survivor-study
#11
Daniel C Bowers, Chaya S Moskowitz, Joanne F Chou, Claire M Mazewski, Joseph P Neglia, Gregory T Armstrong, Wendy M Leisenring, Leslie L Robison, Kevin C Oeffinger
Purpose Little is known about neurologic morbidity attributable to cranial radiotherapy (CRT) -associated meningiomas. Materials and Methods From 4,221 survivors exposed to CRT in the Childhood Cancer Survivor Study, a diagnosis of meningioma and onset of neurologic sequelae were ascertained. Cox proportional hazards regression was used to estimate hazard ratios (HR) and 95% CIs to evaluate the factors associated with neurologic sequelae after subsequent meningioma. Results One hundred ninety-nine meningiomas were identified among 169 participants...
March 24, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28339328/mercaptopurine-ingestion-habits-red-cell-thioguanine-nucleotide-levels-and-relapse-risk-in-children-with-acute-lymphoblastic-leukemia-a-report-from-the-children-s-oncology-group-study-aall03n1
#12
Wendy Landier, Lindsey Hageman, Yanjun Chen, Nancy Kornegay, William E Evans, Bruce C Bostrom, Jacqueline Casillas, David S Dickens, Anne L Angiolillo, Glen Lew, Kelly W Maloney, Leo Mascarenhas, A Kim Ritchey, Amanda M Termuhlen, William L Carroll, Mary V Relling, F Lennie Wong, Smita Bhatia
Purpose Children with acute lymphoblastic leukemia (ALL) are generally instructed to take mercaptopurine (6-MP) in the evening and without food or dairy products. This study examines the association between 6-MP ingestion habits and 6-MP adherence, red cell thioguanine nucleotide (TGN) levels, and risk of relapse in children with TMPT wild-type genotype. Methods Participants included 441 children with ALL receiving oral 6-MP for maintenance. Adherence was monitored over 48,086 patient-days using the Medication Event Monitoring System; nonadherence was defined as adherence rate < 95%...
March 24, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28339145/respiratory-syncytial-virus-host-interaction-in-the-pathogenesis-of-bronchiolitis-and-its-impact-on-respiratory-morbidity-in-later-life
#13
REVIEW
Giovanni A Rossi, Andrew A Colin
Rossi GA, Colin AA(.) Respiratory syncytial virus - host interaction in the pathogenesis of bronchiolitis and its impact on respiratory morbidity in later life. Pediatr Allergy Immunol. Respiratory syncytial virus (RSV) is the most common agent of severe airway disease in infants and young children. Large epidemiologic studies have demonstrated a clear relationship between RSV infection and subsequent recurrent wheezing and asthma into childhood, thought to be predominantly related to long-term changes in neuroimmune control of airway tone rather than to allergic sensitization...
March 24, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28339128/life-course-of-atopy-and-allergy-related-disease-events-in-tropical-sub-saharan-africa-a-birth-cohort-study
#14
Swaib A Lule, Harriet Mpairwe, Margaret Nampijja, Florence Akello, Joyce Kabagenyi, Benigna Namara, Gyaviira Nkurunungi, Dennison Kizito, Joseph Kahwa, Lawrence Muhangi, Stephen Nash, Moses Muwanga, Emily L Webb, Alison M Elliott
BACKGROUND: In high-income countries, allergy related-diseases (ARDs) follow a typical sequence, the "Atopic March". Little is known about the life-course of ARDs in the markedly different, low-income, tropical environment. We describe ARDs in a tropical, African birth cohort. METHODS: Ugandan children were followed from birth to nine years. ISAAC questionnaires were completed at intervals; doctor-diagnosed ARDs were recorded throughout follow-up. Skin prick tests (SPTs) were done at three and nine years...
March 24, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28339061/identification-of-two-novel-mutations-in-the-slco2a1-prostaglandin-transporter-gene-in-a-chinese-patient-with-primary-hypertrophic-osteoarthropathy
#15
Ting Guo, Kai Yang, Lv Liu, Zhi-Ping Tan, Hong Luo
Primary hypertrophic osteoarthropathy (PHO), which is a rare multi‑organic disease characterized by digital clubbing, pachydermia and periosteal reaction, typically begins during childhood or adolescence and progresses gradually over years prior to disease stabilization. To date, only two genes have been reported to be associated with PHO, 15‑hydroxyprostaglandin dehydrogenase and solute carrier organic anion transporter family, member 2A1 (SLCO2A1). However, the pathogenesis and the functions of the underlying genes remain to be fully elucidated...
March 24, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28338919/genetic-overlap-between-schizophrenia-and-developmental-psychopathology-longitudinal-and-multivariate-polygenic-risk-prediction-of-common-psychiatric-traits-during-development
#16
Michel G Nivard, Suzanne H Gage, Jouke J Hottenga, Catharina E M van Beijsterveldt, Abdel Abdellaoui, Meike Bartels, Bart M L Baselmans, Lannie Ligthart, Beate St Pourcain, Dorret I Boomsma, Marcus R Munafò, Christel M Middeldorp
BACKGROUND: Several nonpsychotic psychiatric disorders in childhood and adolescence can precede the onset of schizophrenia, but the etiology of this relationship remains unclear. We investigated to what extent the association between schizophrenia and psychiatric disorders in childhood is explained by correlated genetic risk factors. METHODS: Polygenic risk scores (PRS), reflecting an individual's genetic risk for schizophrenia, were constructed for 2588 children from the Netherlands Twin Register (NTR) and 6127 from the Avon Longitudinal Study of Parents And Children (ALSPAC)...
March 11, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28338917/association-between-serum-levels-of-uric-acid-and-blood-pressure-tracking-in-childhood
#17
Bohyun Park, Hye Ah Lee, Sung Hee Lee, Bo Mi Park, Eun Ae Park, Hae Soon Kim, Su Jin Cho, Hyesook Park
BACKGROUND: Recent studies suggest that high levels of serum uric acid of very early life are a result of the in-utero environment and may lead to elevated blood pressure (BP) in adulthood. However, serum uric acid levels can change throughout life. We investigated the effect of serum uric acid levels in childhood on the BP tracking and analysed BP according to changes in serum uric acid levels in early life. METHODS: A total of 449 children from the Ewha Birth and Growth Cohort study underwent at least 2 follow-up examinations...
March 14, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28338907/fish-and-seafood-consumption-during-pregnancy-and-the-risk-of-asthma-and-allergic-rhinitis-in-childhood-a-pooled-analysis-of-18-european-and-us-birth-cohorts
#18
Nikos Stratakis, Theano Roumeliotaki, Emily Oken, Ferran Ballester, Henrique Barros, Mikel Basterrechea, Sylvaine Cordier, Renate de Groot, Herman T den Dekker, Liesbeth Duijts, Merete Eggesbø, Maria Pia Fantini, Francesco Forastiere, Ulrike Gehring, Marij Gielen, Davide Gori, Eva Govarts, Hazel M Inskip, Nina Iszatt, Maria Jansen, Cecily Kelleher, John Mehegan, Carolina Moltó-Puigmartí, Monique Mommers, Andreia Oliveira, Sjurdur F Olsen, Fabienne Pelé, Costanza Pizzi, Daniela Porta, Lorenzo Richiardi, Sheryl L Rifas-Shiman, Sian M Robinson, Greet Schoeters, Marin Strøm, Jordi Sunyer, Carel Thijs, Martine Vrijheid, Tanja G M Vrijkotte, Alet H Wijga, Manolis Kogevinas, Maurice P Zeegers, Leda Chatzi
Background: It has been suggested that prenatal exposure to n-3 long-chain fatty acids protects against asthma and other allergy-related diseases later in childhood. The extent to which fish intake in pregnancy protects against child asthma and rhinitis symptoms remains unclear. We aimed to assess whether fish and seafood consumption in pregnancy is associated with childhood wheeze, asthma and allergic rhinitis. Methods: We pooled individual data from 60 774 mother-child pairs participating in 18 European and US birth cohort studies...
February 27, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28338874/does-fetal-growth-restriction-cause-later-obesity-pitfalls-in-analyzing-causal-mediators-as-confounders
#19
Michael S Kramer, Xun Zhang, Mourad Dahhou, Seungmi Yang, Richard M Martin, Emily Oken, Robert W Platt
Recent studies finding that small-for-gestational-age (SGA) birth is associated with increased adiposity in childhood and adulthood have been based on analyses "adjusting" for height, weight, or body mass index (BMI; weight (kg)/height (m)2) measured concurrently with the adiposity measurement. To assess the potential for bias due to overadjustment for a causal mediator, we compared 2 approaches to analyzing the association between SGA birth and adiposity outcomes (skinfold thicknesses and bioelectrical impedance measurement of body fat) at age 11...
March 3, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28338830/varying-influences-of-aldosterone-on-the-plasma-potassium-concentration-in-blacks-and-whites
#20
Wanzhu Tu, George J Eckert, Brian S Decker, John Howard Pratt
BACKGROUND: Aldosterone acts to restrain the extracellular potassium (K+) concentration. Blacks have on average lower plasma aldosterone concentrations (PACs) than Whites. Whether this ethnic difference is associated with similar changes in the concentration of K+ is unclear. METHODS: Subjects were Blacks and Whites from an observational study of blood pressure regulation. PAC was known to be significantly lower in Blacks than Whites. We sought to test the hypothesis that the concentration of K+ remains constant despite variability in PAC...
February 27, 2017: American Journal of Hypertension
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