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https://www.readbyqxmd.com/read/29786871/gender-specific-effects-of-selection-for-drinking-in-the-dark-on-the-network-roles-of-coding-and-non-coding-rnas
#1
Ovidiu Dan Iancu, Alex Colville, Beth Wilmot, Robert Searles, Priscila Darakjian, Christina Zheng, Shannon McWeeney, Sunita Kawane, John C Crabbe, Pamela Metten, Denesa Oberbeck, Robert Hitzemann
BACKGROUND: Transcriptional differences between Heterogeneous stock (HS/NPT) mice and High Drinking in the Dark (HDID) selected mouse lines have previously been described based on microarray technology coupled with network based analysis (Iancu et al., 2013b). The network changes were reproducible in two independent selections and largely confined to two distinct network modules; in contrast differential expression appeared more specific to each selected line. The current study extends these results by utilizing RNA-Seq technology, allowing evaluation of the relationship between genetic risk and transcription of non-coding RNA; we additionally evaluate sex-specific transcriptional effects of selection...
May 22, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29786659/deep-learning-to-predict-falls-in-older-adults-based-on-daily-life-trunk-accelerometry
#2
REVIEW
Ahmed Nait Aicha, Gwenn Englebienne, Kimberley S van Schooten, Mirjam Pijnappels, Ben Kröse
Early detection of high fall risk is an essential component of fall prevention in older adults. Wearable sensors can provide valuable insight into daily-life activities; biomechanical features extracted from such inertial data have been shown to be of added value for the assessment of fall risk. Body-worn sensors such as accelerometers can provide valuable insight into fall risk. Currently, biomechanical features derived from accelerometer data are used for the assessment of fall risk. Here, we studied whether deep learning methods from machine learning are suited to automatically derive features from raw accelerometer data that assess fall risk...
May 22, 2018: Sensors
https://www.readbyqxmd.com/read/29778516/facilitators-of-and-barriers-to-hpv-vaccination-among-sexual-and-gender-minority-patients-at-a-boston-community-health-center
#3
Kaan Z Apaydin, Holly B Fontenot, Derri Shtasel, Sannisha K Dale, Christina P C Borba, Christopher S Lathan, Lori Panther, Kenneth H Mayer, Alex S Keuroghlian
BACKGROUND: Young sexual minority individuals have lower human papillomavirus (HPV) vaccine completion rates than the general population, and little is known about how gender minority people perceive HPV vaccination. The aim of this study was to qualitatively identify patient-, provider-, and systems-level barriers and facilitators for HPV vaccination among sexual and gender minority (SGM) people. METHODS: Fifteen SGM-identified individuals, ages 23-26, were recruited at an urban community health center in Boston, MA, that specializes in care for SGM...
May 16, 2018: Vaccine
https://www.readbyqxmd.com/read/29778070/high-intensity-binge-drinking-is-associated-with-alterations-in-spontaneous-neural-oscillations-in-young-adults
#4
Rifqi O Affan, Siyuan Huang, Stephen M Cruz, Lee A Holcomb, Edward Nguyen, Ksenija Marinkovic
Heavy episodic alcohol consumption (also termed binge drinking) contributes to a wide range of health and cognitive deficits, but the associated brain-based indices are poorly understood. The current study used electroencephalography (EEG) to examine spontaneous neural oscillations in young adults as a function of quantity, frequency, and the pattern of their alcohol consumption. Sixty-one young adults (23.4 ± 3.4 years of age) were assigned to binge drinking (BD) and light drinking (LD) groups that were equated on gender, race/ethnic identity, age, educational background, and family history of alcoholism...
January 8, 2018: Alcohol
https://www.readbyqxmd.com/read/29774602/pancreas-transplantation-using-compatible-but-non-identical-abo-blood-group-donors
#5
Santosh Nagaraju, Richard S Mangus, John A Powelson, Jonathan A Fridell
METHODS: A review of all pancreas transplants from a single institution from 01/2003 to 07/2016 (n=606) revealed 41 recipients of a NIC donor pancreas which were matched for age, race, gender, year and type of transplant with 41 ABO identical cases. Groups were compared for allograft survival, incidence of acute cellular rejection (ACR), length of hospital stay, 3-month readmissions and transfusion requirements. Serum haptoglobin and Lactate dehydrogenase were used to identify hemolysis in patients requiring repeated transfusions without overt blood loss...
May 17, 2018: Clinical Transplantation
https://www.readbyqxmd.com/read/29773269/juvenile-onset-systemic-lupus-erythematosus-jsle-pathophysiological-concepts-and-treatment-options
#6
REVIEW
Christian M Hedrich, Eve M D Smith, Michael W Beresford
The systemic autoimmune/inflammatory condition systemic lupus erythematosus (SLE) manifests before the age of 16 years in 10-20% of all cases. Clinical courses are more severe, and organ complications are more common in patients with juvenile SLE. Varying gender distribution in different age groups and increasing severity with younger age and the presence of monogenic disease in early childhood indicate distinct differences in the pathophysiology of juvenile versus adult-onset SLE. Regardless of these differences, classification criteria and treatment options are identical...
August 2017: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/29771930/perspectives-of-human-verification-via-binary-qrs-template-matching-of-single-lead-and-12-lead-electrocardiogram
#7
Vessela Krasteva, Irena Jekova, Ramun Schmid
OBJECTIVE: This study aims to validate the 12-lead electrocardiogram (ECG) as a biometric modality based on two straightforward binary QRS template matching characteristics. Different perspectives of the human verification problem are considered, regarding the optimal lead selection and stability over sample size, gender, age, heart rate (HR). METHODS: A clinical 12-lead resting ECG database, including a population of 460 subjects with two-session recordings (>1 year apart) is used...
2018: PloS One
https://www.readbyqxmd.com/read/29771548/boricua-de-pura-cepa-ethnic-identity-cultural-stress-and-self-concept-in-puerto-rican-youth
#8
Jenny Zhen-Duan, Farrah Jacquez, Emily Sáez-Santiago
OBJECTIVES: The available literature on ethnic identity among Puerto Ricans has focused on those living in the United States, with little to no attention placed on examining ethnic identity and psychological constructs among youth living in Puerto Rico. Using a colonial mentality framework, the current study examined the associations between ethnic identity, cultural stress, and self-concept among adolescent boys and girls living in Puerto Rico. METHOD: The current cross-sectional study surveyed participants (N = 187) recruited from several junior high schools in the metropolitan area in Puerto Rico...
May 17, 2018: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/29769057/patterns-of-care-for-anal-cancer-in-the-united-states-a-comparison-between-academic-and-community-cancer-centers
#9
Victor E Pricolo, Matteo Bonvini, Carlo F Abelli
BACKGROUND: Management of squamous cell carcinoma of the anus (SCCA) is becoming more relevant, as its incidence increases. The purpose of this study was to investigate possible differences in patient population and care delivery for SCCA between academic and community cancer programs in the United States. METHODS: A review of available data from the American College of Surgeons Committee on Cancer National Cancer DataBase focused on gender, age, race, type of health insurance, comorbidity score, distance traveled for care, stage at diagnosis, and therapy utilization (surgery, chemotherapy, and radiation therapy) as first course of treatment (FCT)...
May 16, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29764196/a-dialectical-and-dialogical-approach-to-health-policies-and-programs-the-case-of-open-defecation-in-india
#10
Robin Patric Clair, Rahul Rastogi, Seungyoon Lee, Rosalee A Clawson, Ernest R Blatchley, Charlotte Erdmann
A multi-pronged approach to health policy and programs related to open defecation (OD) is proposed via a qualitative study conducted in rural India. A dialogic and dialectic perspective is employed to interpret the key findings from nine focus groups, highlighting the dialectical views toward OD and latrines. Findings indicate that current policy may be too narrow as it does not fully deal with the multiple reasons, including social communication as well as gender, cultural, health and work identity issues, for OD...
May 15, 2018: Health Communication
https://www.readbyqxmd.com/read/29763683/sexual-and-gender-minority-cigarette-smoking-disparities-an-analysis-of-2016-behavioral-risk-factor-surveillance-system-data
#11
Leah Hoffman, Janine Delahanty, Sarah E Johnson, Xiaoquan Zhao
We examined the association between lesbian, gay, bisexual, and transgender (LGBT) identity, cigarette and e-cigarette use, and potential risk factors in the United States. Using data from 198,057 adults in 26 states in the 2016 Behavioral Risk Factor Surveillance System (BRFSS), we estimated the prevalence of cigarette use, e-cigarette use, and potential risk factors by gender identity and sexual identity. Overall and sex-stratified bivariate and multivariate logistic regressions examined whether the relationship between sexual and gender identity and cigarette and e-cigarette use persisted after adjusting for demographics, socio-economic status, and other unhealthy behaviors...
May 12, 2018: Preventive Medicine
https://www.readbyqxmd.com/read/29761263/measuring-the-health-of-an-invisible-population-lessons-from-the-colorado-transgender-health-survey
#12
Robin Christian, Amy Anderson Mellies, Alison Grace Bui, Rita Lee, Leo Kattari, Courtney Gray
BACKGROUND: Transgender people, those whose gender identity does not match their sex assigned at birth, face barriers to receiving health care. These include discrimination, prohibitive cost, and difficulty finding transgender-inclusive providers. As transgender identities are not typically recognized in public health research, the ability to compare the health of the transgender population to the overall population is limited. OBJECTIVE: The Colorado Transgender Health Survey sought to explore current disparities and their effects on the health of transgender people in Colorado...
May 15, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29753137/perceptions-of-intersectional-stigma-among-diverse-women-living-with-hiv-in-the-united-states
#13
Whitney S Rice, Carmen H Logie, Tessa M Napoles, Melonie Walcott, Abigail W Batchelder, Mirjam-Colette Kempf, Gina M Wingood, Deborah J Konkle-Parker, Bulent Turan, Tracey E Wilson, Mallory O Johnson, Sheri D Weiser, Janet M Turan
Attitudes and behavior that devalue individuals based upon their HIV status (HIV-related stigma) are barriers to HIV prevention, treatment, and wellbeing among women living with HIV. Other coexisting forms of stigma (e.g., racism, sexism) may worsen the effects of HIV-related stigma, and may contribute to persistent racial and gendered disparities in HIV prevention and treatment. Few studies examine perceptions of intersectional stigma among women living with HIV. From June to December 2015, we conducted 76 qualitative interviews with diverse women living with HIV from varied socioeconomic backgrounds enrolled in the Women's Interagency HIV Study (WIHS) in Birmingham, Alabama; Jackson, Mississippi; Atlanta, Georgia; and San Francisco, California...
May 4, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29752630/potentially-reversible-social-deficits-among-transgender-youth
#14
Jack L Turban
Recently, there has been increased attention to a putative relationship between Autism Spectrum Disorder (ASD) and gender dysphoria, the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) diagnosis for those whose gender assigned at birth does not match their gender identity. Studies have shown an over-representation of ASD symptoms among transgender youth. These studies, however, have used scales that are non-specific for ASD. These ASD symptoms may represent social deficits that are secondary to social stress and deprivation, as transgender youth suffer high rates of peer and family rejection...
May 12, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29749299/dyadic-reporting-of-intimate-partner-violence-among-male-couples-in-three-u-s-cities
#15
Nicolas A Suarez, Matthew J Mimiaga, Robert Garofalo, Emily Brown, Anna Marie Bratcher, Taylor Wimbly, Marco A Hidalgo, Samuel Hoehnle, Jennie Thai, Erin Kahle, Patrick S Sullivan, Rob Stephenson
Intimate partner violence (IPV) is a prevalent and pressing public health concern that affects people of all gender and sexual identities. Though studies have identified that male couples may experience IPV at rates as high as or higher than women in heterosexual partnerships, the body of literature addressing this population is still nascent. This study recruited 160 male-male couples in Atlanta, Boston, and Chicago to independently complete individual surveys measuring demographic information, partner violence experience and perpetration, and individual and relationship characteristics that may shape the experience of violence...
May 1, 2018: American Journal of Men's Health
https://www.readbyqxmd.com/read/29749293/decisional-space-determines-saccadic-reaction-times-in-healthy-observers-and-acquired-prosopagnosia
#16
Meike Ramon, Nayla Sokhn, Junpeng Lao, Roberto Caldara
Determining the familiarity and identity of a face have been considered as independent processes. Covert face recognition in cases of acquired prosopagnosia, as well as rapid detection of familiarity have been taken to support this view. We tested P.S. a well-described case of acquired prosopagnosia, and two healthy controls (her sister and daughter) in two saccadic reaction time (SRT) experiments. Stimuli depicted their family members and well-matched unfamiliar distractors in the context of binary gender, or familiarity decisions...
May 11, 2018: Cognitive Neuropsychology
https://www.readbyqxmd.com/read/29746621/revisiting-the-relationship-between-acculturation-and-smoking-cessation-among-mexican-americans
#17
Yessenia Castro, Christine Vinci, Whitney L Heppner, Miguel Ángel Cano, Virmarie Correa-Fernández, David W Wetter
Background: A well-established gender-differentiated association between acculturation and current smoking exists among Latino adults. There are far fewer studies on the potential influence of acculturation on smoking cessation, and extant findings are mixed. Purpose: Using a multidimensional measure of acculturation, the current study examined the independent and interactive associations of gender and acculturation with smoking cessation among Mexican American smokers engaged in a quit attempt...
May 9, 2018: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/29744010/prevention-of-cardiovascular-disease-in-women
#18
REVIEW
Anum Saeed, June Kampangkaew, Vijay Nambi
Cardiovascular diseases are the leading cause of morbidity and mortality among women worldwide. The pathophysiological basis of cardiovascular health among men and women is not identical. This leads to variable cardiovascular responses to stimulus and presentation of cardiovascular disease symptoms, both of which can have a direct effect on treatment outcomes. Traditionally, the enrollment of women in clinical trials has been minimal, resulting in a lack of gender-specific analysis of clinical trial data and, therefore, the absence of concrete risk factor assessment among women...
October 2017: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/29741976/self-reported-autism-spectrum-disorder-symptoms-among-adults-referred-to-a-gender-identity-clinic
#19
Lieke E W Vermaat, Anna I R van der Miesen, Annelou L C de Vries, Thomas D Steensma, Arne Popma, Peggy T Cohen-Kettenis, Baudewijntje P C Kreukels
PURPOSE: The purpose of this study was to (1) investigate autism spectrum disorder (ASD) symptoms in a sample of adults referred for gender dysphoria (GD) compared to typically developing (TD) populations, (2) see whether males assigned at birth with GD (MaBGD s) and females assigned at birth with GD (FaBGD s) differ in ASD symptom levels, (3) study the role of sexual orientation, and (4) investigate ASD symptoms' correlation with GD symptoms. METHODS: The Autism-Spectrum Quotient (AQ) was used to measure ASD symptoms, and the Utrecht Gender Dysphoria Scale (UGDS) was used to measure the intensity of GD...
May 9, 2018: LGBT Health
https://www.readbyqxmd.com/read/29741966/feminine-identity-and-functional-benefits-are-key-factors-in-women-s-decision-making-about-upper-limb-prostheses-a-case-series
#20
Linda Resnik, Shana Klinger, Anisha Gill, Sarah Ekerholm Biester
PURPOSE: Although the DEKA Arm promises new abilities, it is unclear if women with upper limb amputation are willing to avail themselves of this new technology. The study purpose was to understand key factors and tradeoffs that shape women's attitudes towards the DEKA Arm. METHODS: This case series includes three women with transradial amputation. Structured surveys and semi-guided interviews were administered after completion of in-laboratory training and a home trial of the DEKA Arm...
May 9, 2018: Disability and Rehabilitation. Assistive Technology
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