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Pelvic nerves endometriosis

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https://www.readbyqxmd.com/read/28703103/shining-light-in-a-dark-landscape-mri-evaluation-of-unusual-localization-of-endometriosis
#1
Benedetta Gui, Anna Lia Valentini, Valeria Ninivaggi, Maura Miccò, Viola Zecchi, Pier Paolo Grimaldi, Francesco Cambi, Maurizio Guido, Lorenzo Bonomo
Endometriosis is a disease distinguished by the presence of endometrial tissue outside the uterine cavity with intralesional recurrent bleeding and resulting fibrosis. The most common locations for endometriosis are the ovaries, pelvic peritoneum, uterosacral ligaments, and torus uterinus. Typical symptoms are secondary dysmenorrhea and cyclic or chronic pelvic pain. Unusual sites of endometriosis may be associated with specific symptoms depending on the localization. Atypical pelvic endometriosis localizations can occur in the cervix, vagina, round ligaments, ureter, and nerves...
July 2017: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/28683027/pelvic-denervation-procedures-for-dysmenorrhea
#2
Christina Ramirez, Nicole Donnellan
PURPOSE OF REVIEW: Chronic pelvic pain and dysmenorrhea are common conditions affecting reproductive-age women. Surgical pelvic denervation procedures may be a treatment option for women with midline dysmenorrhea, in which medical management is declined by the patient, ineffective at managing symptoms, or medically contraindicated. This review describes the surgical techniques and complications associated with pelvic denervation procedures as well as the current evidence for these procedures in women with primary dysmenorrhea and dysmenorrhea secondary to endometriosis...
August 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28673205/nerve-growth-factor-is-associated-with-sexual-pain-in-women-with-endometriosis
#3
Bo Peng, Hong Zhan, Fahad Alotaibi, Ghadeer M Alkusayer, Mohamed A Bedaiwy, Paul J Yong
Endometriosis is present in 1 in 10 reproductive-age women, and half experience deep dyspareunia (pelvic pain with sexual intercourse). Our objective was to investigate nerve growth factor (NGF) and its receptors (TrkA/p75NTR) in endometriosis-associated deep dyspareunia. A total of 32 women with endometriosis in the posterior pelvic compartment (cul-de-sac/uterosacrals) were included, either with (n = 17) or without (n = 15) deep dyspareunia symptoms confirmed by endovaginal ultrasound-assisted palpation on examination...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28467398/pathophysiology-and-management-of-urinary-tract-endometriosis
#4
REVIEW
Camran Nezhat, Rebecca Falik, Sara McKinney, Louise P King
Endometriosis predominantly affects the pelvic reproductive organs but can also affect the urinary tract. A number of theories for the pathogenesis of endometriosis have been suggested, but the exact mechanisms remain elusive. Endometriotic lesions can be found on both the ureter and bladder, and the optimal therapeutic approach depends on the extent, depth, and location of these lesions. Medical approaches, including hormonal therapies such as GnRH agonists and oral contraceptives, tend to be a temporary measure, but can be useful in a preoperative setting or if the patient is unsuitable for surgery, and are also useful as a postoperative treatment...
June 2017: Nature Reviews. Urology
https://www.readbyqxmd.com/read/28339446/pulsed-radiofrequency-ablation-of-pudendal-nerve-for-treatment-of-a-case-of-refractory-pelvic-pain
#5
Vadim Petrov-Kondratov, Avneesh Chhabra, Stephanie Jones
Pudendal neuralgia (PN) is a result of pudendal nerve entrapment or injury, also called "Alcock syndrome." Pain that develops is often chronic, and at times debilitating. If conservative measures fail, invasive treatment modalities can be considered. The goal of this case report is to add to a small body of literature that a pulsed radiofrequency (PRF) ablation can be effectively used to treat PN and to show that high resolution MR neurography imaging can be used to detect pudendal neuropathy. CASE PRESENTATION: We present a case of a 51-year-old woman with 5 years of worsening right groin and vulva pain...
March 2017: Pain Physician
https://www.readbyqxmd.com/read/28323223/robotic-assisted-conservative-excision-of-retrocervical-rectal-deep-infiltrating-endometriosis-a-case-series
#6
Alfredo Ercoli, Emma Bassi, Stefania Ferrari, Daniela Surico, Anna Fagotti, Francesco Fanfani, Fiorenzo De Cicco, Nicola Surico, Giovanni Scambia
Deep infiltrating endometriosis (DIE) is a complex disease that impairs the quality of life and the fertility of women. Colorectal DIE accounts for 70% to 93% of all the intestinal endometriotic sites and frequently needs a surgical approach. However, the indications for the surgical management of this condition are still controversial. From March 2010 to June 2014, we scheduled 33 consecutive patients presenting with retrocervical-rectal DIE of any diameter not involving the mucosa nor producing rectal stenosis > 50% for laparoscopic robotic assisted nerve-sparing rectal nodulectomy (LRN)...
March 18, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27951614/nerve-sparing-and-surgery-for-deep-infiltrating-endometriosis-pessimism-of-the-intellect-or-optimism-of-the-will
#7
Basma Darwish, Horace Roman
Nerve-sparing surgery is an emerging technique for surgery-related dysfunction. Within the past 15 years, an essential progress in recognition and understanding of the anatomy of the pelvic autonomous nervous system has been made. Surgical preservation of vegetative nerves has become well known in many cancer centers. The technique has led to improvement of the quality of life following oncologic radical procedures. Positive results have led to the adoption of such techniques in the surgical treatment of deep infiltrating endometriosis in an aim to prevent urinary, rectal, and sexual dysfunction...
January 2017: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/27678760/nerve-sparing-rectosigmoid-resection-and-low-rectal-anastomosis-for-deep-pelvic-endometriosis
#8
S Aksu, S Misirlioglu, C Taskiran, B Urman
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27666420/evaluation-of-the-sacral-nerve-plexus-in-pelvic-endometriosis-by-three-dimensional-mr-neurography
#9
Xiaoling Zhang, Meizhi Li, Jian Guan, Huanjun Wang, Shurong Li, Yan Guo, Mingjuan Liu
PURPOSE: To investigate the feasibility of three-dimensional MR neurography (3D MRN) for the sacral plexus using sampling perfection with application-optimized contrasts using different flip angle evolution (SPACE) sequences, and to demonstrate structural abnormalities in the pelvic nerve of women with pelvic endometriosis. MATERIALS AND METHODS: Twenty patients with pelvic endometriosis and 20 healthy controls were examined by contrast-enhanced 3D short time inversion recovery T2-weighted imaging (CE 3D STIR T2WI) SPACE sequences on 3 Tesla MRI...
September 26, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27558236/reduced-sympathetic-innervation-in-endometriosis-is-associated-to-semaphorin-3c-and-3f-expression
#10
Claudia Scheerer, Sergio Frangini, Vito Chiantera, Sylvia Mechsner
Endometriosis is a chronic inflammatory disease and one of the most common causes of pelvic pain. The mechanisms underlying pain emergence or chronic inflammation during endometriosis remain unknown. Several chronic inflammatory diseases including endometriosis show reduced amounts of noradrenergic nerve fibers. The source of the affected innervation is still unclear. Semaphorins represent potential elicitors, due to their known role as axonal guidance cues, and are suggested as nerve repellent factors in different chronic inflammatory diseases...
August 24, 2016: Molecular Neurobiology
https://www.readbyqxmd.com/read/27454463/genome-wide-association-analysis-of-pain-severity-in-dysmenorrhea-identifies-association-at-chromosome-1p13-2-near-the-nerve-growth-factor-locus
#11
Amy V Jones, James R F Hockley, Craig Hyde, Donal Gorman, Ana Sredic-Rhodes, James Bilsland, Gordon McMurray, Nicholas A Furlotte, Youna Hu, David A Hinds, Peter J Cox, Serena Scollen
Dysmenorrhea is a common chronic pelvic pain syndrome affecting women of childbearing potential. Family studies suggest that genetic background influences the severity of dysmenorrhea, but genetic predisposition and molecular mechanisms underlying dysmenorrhea are not understood. In this study, we conduct the first genome-wide association study to identify genetic factors associated with dysmenorrhea pain severity. A cohort of females of European descent (n = 11,891) aged 18 to 45 years rated their average dysmenorrhea pain severity...
November 2016: Pain
https://www.readbyqxmd.com/read/27296002/-morphological-substrate-and-pathogenetic-mechanisms-of-pelvic-pain-syndrome-in-endometriosis-part-ii-peripheral-nerve-tissue-remodeling-in-the-foci-of-endometriosis
#12
E A Kogan, A S Ovakimyan, N B Paramonova, N M Faizullina, I F Kazachenko, L V Adamyan
UNLABELLED: Endometriosis (EM) is morphologically characterized by the development of extrauterine endometrioid heterotopies, the major clinical symptoms of which is chronic pelvic pain, which is a serious problem not only in modern gynecology, but also in public health as a whole. AIM: to investigate neurogenic markers in the foci of EM of various sites and histological structure in women with and without pain syndrome. MATERIAL AND METHODS: The investigation was performed using the operative material (resected segments of the intestine, bladder, rectovaginal septum, and small pelvic peritoneum) obtained from 52 women with an intraoperative and morphologically verified diagnosis of EM and (Group 1) and without (Group 2) pain syndrome...
May 2016: Arkhiv Patologii
https://www.readbyqxmd.com/read/27118342/-deep-infiltrating-endometriosis-surgical-management-and-pelvic-nerves-injury
#13
M Fermaut, K Nyangoh Timoh, C Lebacle, D Moszkowicz, G Benoit, T Bessede
OBJECTIVES: Deep pelvic endometriosis surgery may need substantial excisions, which in turn expose to risks of injury to the pelvic nerves. To limit functional complications, nerve-sparing surgical techniques have been developed but should be adapted to the specific multifocal character of endometriotic lesions. The objective was to identify the anatomical areas where the pelvic nerves are most at risk of injury during endometriotic excisions. METHODS: The Medline and Embase databases have been searched for available literature using the keywords "hypogastric nerve or hypogastric plexus [Mesh] or autonomic pathway [Mesh], anatomy, endometriosis, surgery [Mesh]"...
May 2016: Gynécologie, Obstétrique & Fertilité
https://www.readbyqxmd.com/read/27078713/sciatic-neuroendometriosis-magnetic-resonance-imaging-defined-perineural-spread-of-endometriosis
#14
Canan Cimsit, Tevfik Yoldemir, Ihsan Nuri Akpinar
Catamenial sciatic radiculopathy resulting from endometriosis is a rare presentation of a common disease in which the pathogenesis of pain is still under debate. A 32-year-old woman presented complaining of infertility, catamenial sciatica, and pelvic and gluteal pain. Magnetic resonance imaging showed endometriotic infiltration of the left proximal lumbosacral plexus, sacral nerve track, sciatic nerve at the sciatic notch and pudendal nerve along the iliococcygeus muscle, together with left endometrioma and deep infiltrating endometriosis lesions...
April 14, 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/26968908/autonomic-denervation-a-new-aetiological-framework-for-clinical-obstetrics-and-gynaecology
#15
M J Quinn
The hypothesis is that many clinical conditions in obstetrics and gynaecology result from the diverse and varying consequences of injuries to pelvic autonomic nerves. These injuries result from difficult first labours, persistent physical efforts during defaecation, and, medical and surgical techniques for evacuation of the uterus. The neuro-immunohistochemical "signatures" of these injuries are variations of the Dixon-Robertson-Brosens (DRB) lesion in preeclampsia, where there is hyperplasia of the tunica intima and media of arterioles with narrowing of the lumen of the vessel...
April 2016: Medical Hypotheses
https://www.readbyqxmd.com/read/26926975/chronic-pelvic-pain-in-women
#16
REVIEW
Linda M Speer, Saudia Mushkbar, Tara Erbele
Chronic pelvic pain in women is defined as persistent, noncyclic pain perceived to be in structures related to the pelvis and lasting more than six months. Often no specific etiology can be identified, and it can be conceptualized as a chronic regional pain syndrome or functional somatic pain syndrome. It is typically associated with other functional somatic pain syndromes (e.g., irritable bowel syndrome, nonspecific chronic fatigue syndrome) and mental health disorders (e.g., posttraumatic stress disorder, depression)...
March 1, 2016: American Family Physician
https://www.readbyqxmd.com/read/26688332/sciatic-endometriosis-induces-mechanical-hypersensitivity-segmental-nerve-damage-and-robust-local-inflammation-in-rats
#17
S Chen, W Xie, J A Strong, J Jiang, J-M Zhang
BACKGROUND: Endometriosis is a common cause of pain including radicular pain. Ectopic endometrial tissue may directly affect peripheral nerves including the sciatic, which has not been modelled in animals. METHODS: We developed a rat model for sciatic endometriosis by grafting a piece of autologous uterine tissue around the sciatic nerve. Control animals underwent a similar surgery but received a graft of pelvic fat tissue. RESULTS: The uterine grafts survived and developed fluid-filled cysts; the adjacent nerve showed signs of swelling and damage...
August 2016: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/26680392/laparascopic-neurolysis-of-deep-endometriosis-infiltrating-left-femoral-nerve-case-report
#18
Cláudia Andrade, Sónia Barata, Francisco António, Conceição Alho, Carlos Calhaz-Jorge, Filipa Osório
Pelvic endometriosis may infiltrate somatic nerves causing severe neuropathic symptoms with a high impact on quality of life. It is a medical condition poorly known, and few published data about involvement of femoral nerve are available. We report an isolated unilateral endometriosis lesion of the left lumbar region infiltrating the femoral nerve in a 38-year-old woman. She described severe dysmenorrhea, dyspareunia, dischezia, and chronic pelvic pain with irradiation to the anterior part of the left thigh...
November 2015: Surgical Technology International
https://www.readbyqxmd.com/read/26472151/are-endometrial-nerve-fibres-unique-to-endometriosis-a-prospective-case-control-study-of-endometrial-biopsy-as-a-diagnostic-test-for-endometriosis-in-women-with-pelvic-pain
#19
Lenore Ellett, Emma Readman, Marsali Newman, Kate McIlwaine, Rocio Villegas, Nisha Jagasia, Peter Maher
STUDY QUESTION: Can the presence of endometrial nerve fibres be used as a diagnostic test for endometriosis in women with pelvic pain? SUMMARY ANSWER: Endometrial fine nerve fibres were seen in the endometrium of women both with and without endometriosis, making their detection a poor diagnostic tool for endometriosis. WHAT IS KNOWN ALREADY: Laparoscopy and biopsy are currently the gold standard for making a diagnosis of endometriosis. It has been reported that small density nerve fibres in the functional layer of the endometrium are unique to women with endometriosis and hence nerve fibre detection could function as a less invasive diagnostic test of endometriosis...
December 2015: Human Reproduction
https://www.readbyqxmd.com/read/26460864/laparascopic-neurolysis-of-deep-endometriosis-infiltrating-left-femoral-nerve-case-report
#20
Cláudia Andrade, Sónia Barata, Francisco António, Conceição Alho, Carlos Calhaz-Jorge, Filipa Osório
Pelvic endometriosis may infiltrate somatic nerves causing severe neuropathic symptoms with a high impact on quality of life. It is a medical condition poorly known, and few published data about involvement of femoral nerve are available. We report an isolated unilateral endometriosis lesion of the left lumbar region infiltrating the femoral nerve in a 38-year-old woman. She described severe dysmenorrhea, dyspareunia, dischezia, and chronic pelvic pain with irradiation to the anterior part of the left thigh...
October 7, 2015: Surgical Technology International
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