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https://www.readbyqxmd.com/read/28651300/noninvasive-assessment-of-advanced-fibrosis-based-on-hepatic-volume-in-patients-with-nonalcoholic-fatty-liver-disease
#1
Tatsuya Hayashi, Satoshi Saitoh, Kei Fukuzawa, Yoshinori Tsuji, Junji Takahashi, Yusuke Kawamura, Norio Akuta, Masahiro Kobayashi, Kenji Ikeda, Takeshi Fujii, Tosiaki Miyati, Hiromitsu Kumada
Background/Aims: Noninvasive liver fibrosis evaluation was performed in patients with nonalcoholic fatty liver disease (NAFLD). We used a quantitative method based on the hepatic volume acquired from gadoxetate disodium-enhanced (Gd-EOB-DTPA-enhanced) magnetic resonance imaging (MRI) for diagnosing advanced fibrosis in patients with NAFLD. Methods: A total of 130 patients who were diagnosed with NAFLD and underwent Gd-EOB-DTPA-enhanced MRI were retrospectively included...
June 27, 2017: Gut and Liver
https://www.readbyqxmd.com/read/28651263/quality-and-dose-optimized-ct-trauma-protocol-recommendation-from-a-university-level-i-trauma-center
#2
Johannes Kahn, David Kaul, Georg Böning, Roman Rotzinger, Patrick Freyhardt, Philipp Schwabe, Martin H Maurer, Diane Miriam Renz, Florian Streitparth
Purpose As a supra-regional level-I trauma center, we evaluated computed tomography (CT) acquisitions of polytraumatized patients for quality and dose optimization purposes. Adapted statistical iterative reconstruction [(AS)IR] levels, tube voltage reduction as well as a split-bolus contrast agent (CA) protocol were applied. Materials and Methods 61 patients were split into 3 different groups that differed with respect to tube voltage (120 - 140 kVp) and level of applied ASIR reconstruction (ASIR 20 - 50 %)...
June 26, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28650888/false-positive-uptake-of-radioiodine-in-renal-hamartoma-in-a-patient-with-differentiated-thyroid-cancer
#3
Guohua Shen, Zhongzhi Qi, Rui Huang, Bin Liu, Anren Kuang
A 46-year-old woman with a history of papillary thyroid cancer status post total thyroidectomy underwent the second I radioiodine ablation therapy for lung metastases. Posttherapeutic whole-body I planar images showed diffuse uptake in the lungs and intense focal activity in both sides of the upper abdomen. SPECT/CT of the abdomen localized the uptake in the upper pole of the left kidney and the lower pole of the right kidney. The patient received bilateral partial nephrectomy with pathology demonstrating that these 2 renal lesions were renal hamartomas...
June 24, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28650389/prevalence-of-pancreatic-cystic-lesions-is-associated-with-diabetes-mellitus-and-obesity-an-analysis-of-5296-individuals-who-underwent-a-preventive-medical-examination
#4
Suguru Mizuno, Hiroyuki Isayama, Yousuke Nakai, Takeharu Yoshikawa, Kazunaga Ishigaki, Saburo Matsubara, Natsuyo Yamamoto, Hideaki Ijichi, Keisuke Tateishi, Minoru Tada, Naoto Hayashi, Kazuhiko Koike
OBJECTIVES: Pancreatic cystic lesions (PCLs) are considered precursors of pancreatic cancer. Diabetes mellitus (DM) and obesity are known as risk factors for pancreatic cancer. We investigated the prevalence of PCLs in the general population and the relationship between PCLs and DM/obesity. METHODS: This cross-sectional analysis included 5296 individuals who underwent a preventive medical examination between October 2006 and June 2013 at our institution. Magnetic resonance imaging, including magnetic resonance cholangiopancreatography, was performed using a 3...
June 22, 2017: Pancreas
https://www.readbyqxmd.com/read/28650235/evaluation-of-infrared-thermography-as-a-diagnostic-tool-to-predict-heat-stress-events-in-feedlot-cattle
#5
Ellen M Unruh, Miles E Theurer, Brad J White, Robert L Larson, James S Drouillard, Nora Schrag
OBJECTIVE To determine whether infrared thermographic images obtained the morning after overnight heat abatement could be used as the basis for diagnostic algorithms to predict subsequent heat stress events in feedlot cattle exposed to high ambient temperatures. ANIMALS 60 crossbred beef heifers (mean ± SD body weight, 385.8 ± 20.3 kg). PROCEDURES Calves were housed in groups of 20 in 3 pens without any shade. During the 6 am and 3 pm hours on each of 10 days during a 14-day period when the daily ambient temperature was forecasted to be > 29...
July 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28650110/reproducibility-of-in-vivo-magnetic-resonance-imaging-t1-rho-and-t2-relaxation-time-measurements-of-hip-cartilage-at-3-0t-in-healthy-volunteers
#6
Angeline Nemeth, Lucy Di Marco, Florent Boutitie, Michael Sdika, Denis Grenier, Muriel Rabilloud, Olivier Beuf, Jean-Baptiste Pialat
PURPOSE: To assess the T1 ρ and T2 values in the hip cartilage of healthy volunteers and to evaluate the reproducibility of these measurements. MATERIALS AND METHODS: The right hip joint of 30 asymptomatic volunteers was explored with 3T magnetic resonance imaging (MRI). Quantitative 3D T1 ρ- and T2 -maps sequences were repeated twice with a 30-minute delay (immediate reproducibility). The same protocol was repeated 14 days later (short-term reproducibility). Immediate and short-term reproducibility were estimated using coefficients of variation and correlation concordance coefficients (CCC)...
June 26, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28649898/a-review-of-body-composition-and-pharmacokinetics-in-oncology
#7
Jessica J Hopkins, Michael B Sawyer
Body surface area dosing of chemotherapeutic agents is based on limited scientific data, and often results in unpredictable plasma drug levels. Cross-sectional computed tomography (CT) imaging provides an accurate measurement of lean mass. This review summarizes emerging roles of lean mass in predicting pharmacokinetics and drug toxicities in cancer patients. Areas covered: A concise review of body composition measurement with CT cross-sectional imaging and its relationship to drug pharmacokinetics and toxicities...
June 26, 2017: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/28649640/mri-derived-diffusion-parameters-in-the-human-optic-nerve-and-its-surrounding-sheath-during-head-down-tilt
#8
Darius A Gerlach, Karina Marshall-Goebel, Khader M Hasan, Larry A Kramer, Noam Alperin, Joern Rittweger
More than half of astronauts present with significant neuro-ophthalmic findings during 6-month missions onboard the International Space Station. Although the underlying cause of this Microgravity Ocular Syndrome is currently unknown, alterations in cerebrospinal fluid dynamics within the optic nerve sheath may play a role. In the presented study, diffusion tensor imaging was used to assess changes in diffusivity of the optic nerve and its surrounding sheath during head-down tilt, a ground-based model of microgravity...
2017: NPJ Microgravity
https://www.readbyqxmd.com/read/28649624/spaceflight-induced-neuroplasticity-in-humans-as-measured-by-mri-what-do-we-know-so-far
#9
Angelique Van Ombergen, Steven Laureys, Stefan Sunaert, Elena Tomilovskaya, Paul M Parizel, Floris L Wuyts
Space travel poses an enormous challenge on the human body; microgravity, ionizing radiation, absence of circadian rhythm, confinement and isolation are just some of the features associated with it. Obviously, all of the latter can have an impact on human physiology and even induce detrimental changes. Some organ systems have been studied thoroughly under space conditions, however, not much is known on the functional and morphological effects of spaceflight on the human central nervous system. Previous studies have already shown that central nervous system changes occur during and after spaceflight in the form of neurovestibular problems, alterations in cognitive function and sensory perception, cephalic fluid shifts and psychological disturbances...
2017: NPJ Microgravity
https://www.readbyqxmd.com/read/28649563/symptomatic-congenital-cytomegalovirus-infection-in-children-of-seropositive-women
#10
Ines Mack, Marie-Anne Burckhardt, Ulrich Heininger, Friederike Prüfer, Sven Schulzke, Sven Wellmann
Cytomegalovirus (CMV) is the most frequent congenital virus infection worldwide. The risk of congenital CMV (cCMV) transmission is highest in seronegative women who acquire primary CMV infection during pregnancy. A growing body of evidence indicates that secondary CMV infections in pregnant women with preconceptual immunity (either through reactivation of latent virus or re-infection with a new strain of CMV) contribute to a much greater proportion of symptomatic cCMV than was previously thought. Here, we describe a case of symptomatic cCMV infection in the newborn of a woman with proven immunity prior to pregnancy...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28649394/functional-neuroimaging-and-chorea-a-systematic-review
#11
REVIEW
Debra J Ehrlich, Ruth H Walker
Chorea is a hyperkinetic movement disorder consisting of involuntary irregular, flowing movements of the trunk, neck or face. Although Huntington's disease is the most common cause of chorea in adults, chorea can also result from many other neurodegenerative, metabolic, and autoimmune conditions. While the pathophysiology of these different conditions is quite variable, recent advances in functional imaging have enabled the development of new methods for analysis of brain activity and neuronal dysfunction. In this paper we review the growing body of functional imaging data that has been performed in chorea syndromes and identify particular trends, which can be used to better understand the underlying network changes within the basal ganglia...
2017: Journal of Clinical Movement Disorders
https://www.readbyqxmd.com/read/28649300/negative-body-experience-in-women-with-early-childhood-trauma-associations-with-trauma-severity-and-dissociation
#12
Mia Scheffers, Maike Hoek, Ruud J Bosscher, Marijtje A J van Duijn, Robert A Schoevers, Jooske T van Busschbach
Background: A crucial but often overlooked impact of early life exposure to trauma is its far-reaching effect on a person's relationship with their body. Several domains of body experience may be negatively influenced or damaged as a result of early childhood trauma. Objective: The aim of this study was to investigate disturbances in three domains of body experience: body attitude, body satisfaction, and body awareness. Furthermore, associations between domains of body experience and severity of trauma symptoms as well as frequency of dissociation were evaluated...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/28649080/effects-of-oral-administration-of-black-seed-nigella-sativa-oil-on-histomorphometric-dynamics-of-testes-and-testosterone-profile-in-rabbits
#13
Zaima Umar, Anas Sarwar Qureshi, Sarmad Rehan, Misbah Ijaz, Tanzeela Faisal, Saqib Umar
The present study was conducted to evaluate the influence of oral administration of black seed (Nigella sativa) oil on histomorphometrical characteristics of testes and testosterone profile in adult rabbits. Twenty adult male rabbits aged seven months were divided into two groups: control and treated. Black seed oil was administrated orally for 60 days at 5ml/kg body weight/day on daily basis in addition to the food and water ad lib to the treated group. Biometric parameters of the testes were recorded immediately after their removal...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28648916/long-term-changes-in-time-spent-walking-and-subsequent-cognitive-and-structural-brain-changes-in-older-adults
#14
John R Best, Caterina Rosano, Howard J Aizenstein, Qu Tian, Robert M Boudreau, Hilsa N Ayonayon, Suzanne Satterfield, Eleanor M Simonsick, Stephanie Studenski, Kristine Yaffe, Teresa Liu-Ambrose
Previous studies have shown that more active older adults have better cognition and brain health based on a variety of structural neuroimaging measures. Nevertheless, the effects of maintaining physical activity (PA) over an extended period of time on future changes in older adults' cognition and brain structure are unknown. Participants were 141 initially well-functioning community-dwelling older adults (aged 70-79 years at baseline; 60% female; 42% black) studied over a 13-year period. PA (self-reported time spent walking) was assessed annually from years 1 to 10...
June 6, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28648410/the-great-unknown-a-systematic-literature-review-about-risk-associated-with-intraoperative-imaging-during-orthopaedic-surgeries
#15
REVIEW
Amir Matityahu, Ryan K Duffy, Sabine Goldhahn, Alexander Joeris, Peter H Richter, Florian Gebhard
INTRODUCTION: Modern techniques in orthopaedic surgery using minimally invasive procedures, and increased use of fluoroscopic imaging present a potential increased risk to surgeons due to ionizing radiation exposure. This article is a systematic review of recent literature on radiation exposure of orthopaedic surgeons. MATERIALS AND METHODS: Pubmed and Cochrane searches were performed on intraoperative radiation exposure covering English and German articles published between 1...
April 21, 2017: Injury
https://www.readbyqxmd.com/read/28648301/associations-of-early-kidney-disease-with-brain-magnetic-resonance-imaging-and-cognitive-function-in-african-americans-with-type-2-diabetes-mellitus
#16
Barry I Freedman, Kaycee M Sink, Christina E Hugenschmidt, Timothy M Hughes, Jeff D Williamson, Christopher T Whitlow, Nicholette D Palmer, Michael E Miller, Laura C Lovato, Jianzhao Xu, S Carrie Smith, Lenore J Launer, Joshua I Barzilay, Robert M Cohen, Mark D Sullivan, R Nick Bryan, Benjamin C Wagner, Donald W Bowden, Joseph A Maldjian, Jasmin Divers
BACKGROUND: Relationships between early kidney disease, neurocognitive function, and brain anatomy are poorly defined in African Americans with type 2 diabetes mellitus (T2DM). STUDY DESIGN: Cross-sectional associations were assessed between cerebral anatomy and cognitive performance with estimated glomerular filtration rate (eGFR) and urine albumin-creatinine ratio (UACR) in African Americans with T2DM. SETTING & PARTICIPANTS: African Americans with cognitive testing and cerebral magnetic resonance imaging (MRI) in the African American-Diabetes Heart Study Memory in Diabetes (AA-DHS MIND; n=512; 480 with MRI) and Action to Control Cardiovascular Risk in Diabetes (ACCORD) MIND (n=484; 104 with MRI) studies...
June 22, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28647522/functional-medium-term-results-after-autologous-matrix-induced-chondrogenesis-for-osteochondral-lesions-of-the-talus-a-5-year-prospective-cohort-study
#17
Oliver Gottschalk, Sebastian Altenberger, Sebastian Baumbach, Stefanie Kriegelstein, Florian Dreyer, Alexander Mehlhorn, Hubert Hörterer, Andreas Töpfer, Anke Röser, Markus Walther
Autologous matrix-induced chondrogenesis (AMIC) has gained popularity in the treatment of osteochondral lesions of the talus. Previous studies have presented promising short-term results for AMIC talar osteochondral lesion repair, a 1-step technique using a collagen type I/III bilayer matrix. The aim of the present study was to investigate the mid-term effects. The 5-year results of a prospective cohort study are presented. All patients underwent an open AMIC procedure for a talar osteochondral lesion. Data analysis included general demographic data, preoperative magnetic resonance imaging findings, intraoperative details, and German version of the Foot Function Index (FFI-D) scores preoperatively and at 1 and 5 years after surgery...
June 21, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28647449/igrt-and-motion-management-during-lung-sbrt-delivery
#18
REVIEW
Vincent Caillet, Jeremy T Booth, Paul Keall
Patient motion can cause misalignment of the tumour and toxicities to the healthy lung tissue during lung stereotactic body radiation therapy (SBRT). Any deviations from the reference setup can miss the target and have acute toxic effects on the patient with consequences onto its quality of life and survival outcomes. Correction for motion, either immediately prior to treatment or intra-treatment, can be realized with image-guided radiation therapy (IGRT) and motion management devices. The use of these techniques has demonstrated the feasibility of integrating complex technology with clinical linear accelerator to provide a higher standard of care for the patients and increase their quality of life...
June 21, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28647385/hunger-and-disinhibition-but-not-cognitive-restraint-are-associated-with-central-norepinephrine-transporter-availability
#19
A Bresch, M Rullmann, J Luthardt, G A Becker, M Patt, Y-S Ding, A Hilbert, O Sabri, S Hesse
The relationship between food-intake related behaviours measured by the Three-Factor Eating Questionnaire (TFEQ) and in vivo norepinephrine transporter (NET) availability has not been explored yet. We investigated ten obese individuals (body mass index (BMI) 42.4 ± 3.7 kg/m(2)) and ten normal-weight healthy controls (HC, BMI 23.9 ± 2.5 kg/m(2)) with (S,S)-[(11)C]-O-methylreboxetine ([(11)C]MRB) positron emission tomography (PET). All participants completed the TFEQ, which measures cognitive restraint, disinhibition and hunger...
June 21, 2017: Appetite
https://www.readbyqxmd.com/read/28646645/comorbidity-assessment-in-patients-with-oral-squamous-cell-carcinoma-can-imaging-techniques-fludeoxyglucose-positron-emission-tomographic-computed-tomography-and-contrast-enhanced-computed-tomography-provide-additional-information
#20
Matthias Troeltzsch, Florian Andreas Probst, Axel Rominger, Ulrich Müller-Lisse, Monika Probst, Katharina Obermeier, Michael Ehrenfeld, Sven Otto
PURPOSE: This study evaluated the role of imaging staging examinations (positron-emission tomographic computed tomography [PET/CT] and contrast-enhanced computed tomography [ceCT]) for the assessment of the comorbidity status of patients with oral squamous cell carcinoma (OSCC). A binary null hypothesis was drafted: 1) imaging staging examinations do not augment knowledge about the comorbidity status of patients with OSCC and 2) there is no difference between PET/CT and ceCT in this regard...
May 31, 2017: Journal of Oral and Maxillofacial Surgery
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