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https://www.readbyqxmd.com/read/29935493/the-effect-of-exercise-on-breast-cancer-related-lymphedema-what-the-lymphatic-surgeon-needs-to-know
#1
Daniel Panchik, Sarah Masco, Patrice Zinnikas, Brooke Hillriegel, Tori Lauder, Erica Suttmann, Vernon Chinchilli, Maureen McBeth, William Hermann
BACKGROUND:  Breast cancer-related lymphedema (BCRL) affects many areas of daily living. Individuals with lymphedema may experience chronic and progressive swelling, recurrent skin infections, and decreased self-image and quality of life. For many years, it was considered best practice for this population to avoid exercise; however, in recent years, research has begun to challenge this belief. This systematic review and meta-analyses examined the recent literature on the effects of exercise for patients with, or at risk for, BCRL to inform best practice...
June 23, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29935414/correlation-between-clinical-and-cognitive-aspects-and-nutritional-indicators-of-elderly-patients-with-new-onset-epilepsy
#2
Gloria Maria A S Tedrus, Silvana Mariana Screbenich, Tamires Barbosa Nascimento Santos
OBJECTIVE: Nutritional indicators were correlated with cognitive and clinical aspects of 25 elderly patients with new-onset epilepsy (EPWE). The nutritional indicators of the EPWE were compared with those of a similar control group at a significance level of p < 0.05. RESULTS: There was lower cognitive performance, greater risk of malnutrition and muscle tissue depletion, and higher waist circumference (WC) in the EPWE. Longer epilepsy duration was correlated with loss of muscle mass (Pearson's correlation: 0...
June 20, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29935236/association-between-nonalcoholic-fatty-liver-disease-and-colorectal-tumours-in-asymptomatic-adults-undergoing-screening-colonoscopy-a-systematic-review-and-meta-analysis
#3
Alessandro Mantovani, Marco Dauriz, Christopher D Byrne, Amedeo Lonardo, Giacomo Zoppini, Enzo Bonora, Giovanni Targher
BACKGROUND: It is currently uncertain whether non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of colorectal tumours. We performed a meta-analysis of relevant observational studies to quantify the magnitude of the association between NAFLD and risk of colorectal adenomas and cancer. METHODS: We searched PubMed, Scopus and Web of Science from January 2000 to November 2017 using pre-defined keywords to identify observational studies of asymptomatic adults undergoing screening colonoscopy, in which NAFLD was diagnosed by imaging or histology...
June 20, 2018: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29934276/targeting-accuracy-of-image-guided-stereotactic-body-radiation-therapy-for-hepatocellular-carcinoma-in-real-life-clinical-practice-in-vivo-assessment-using-hepatic-parenchymal-changes-on-gd-eob-dtpa-enhanced-magnetic-resonance-images
#4
Jinhong Jung, Hojin Kim, Sang Min Yoon, Byungchul Cho, Yeon Joo Kim, Jungwon Kwak, Jong Hoon Kim
PURPOSE: Stereotactic body radiation therapy (SBRT) for hepatocellular carcinoma (HCC) has emerged as an alternative treatment option when curative treatment modalities cannot be applied. Although excellent local tumor control has been achieved with SBRT, the targeting accuracy in real-life practice remains poorly understood. We proposed an in vivo assessment of targeting accuracy using hepatic parenchymal changes observed on gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance (MR) images and applied this method to investigate the "real-life" targeting accuracy of image-guided SBRT...
May 14, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29934196/evidence-for-dopaminergic-axonal-degeneration-as-an-early-pathological-process-in-parkinson-s-disease
#5
REVIEW
Gerard W O'Keeffe, Aideen M Sullivan
Parkinson's disease is a common neurodegenerative disorder presenting with a variety of motor and non-motor symptoms. The motor symptoms manifest as a result of the progressive degeneration of midbrain dopaminergic neurons. The axons of these neurons project to the striatum as the nigrostriatal pathway, which is a crucial part of the basal ganglia circuitry controlling movement. In addition to the neuronal degeneration, abnormal intraneuronal α-synuclein protein inclusions called Lewy bodies and Lewy neurites increase in number and spread throughout the nervous system as the disease progresses...
June 19, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29934132/body-image-dis-satisfaction-among-low-income-adult-women
#6
Natália Luiza Kops, Marina Bessel, Daniela Riva Knauth, Maira Caleffi, Eliana Marcia Wendland
BACKGROUND & AIMS: A better understanding of the factors that affect self-perception of body characteristics may play an important role in weight control practices. The objective of this study was to analyze body weight perception and body image satisfaction in low-income adult women in Southern Brazil. METHODS: This was a cross-sectional survey study in a cohort of women recruited from areas of social vulnerability in the city of Porto Alegre, RS. A random sample (n = 218) of women was interviewed, and socioeconomic and lifestyle factors, body image perception using the Stunkard Scale, body weight estimation, weight concern and duplicate anthropometric measurements were obtained...
June 13, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29933722/what-do-australian-dermatologists-expect-to-be-paid-for-store-and-forward-teledermoscopy-a-preliminary-investigation
#7
Centaine L Snoswell, Jennifer A Whitty, Liam J Caffery, Anna Finnane, H Peter Soyer
Introduction Determining appropriate remuneration for teledermoscopy service is important because inadequate remuneration can be a barrier to practitioner uptake and participation. This study explores dermatologist remuneration expectations for a single lesion store-and-forward teledermoscopy consultation. Methods Fourteen dermatologists participated in telephone interviews during May-June 2017. Questions regarding remuneration focused on a clinical scenario involving teledermoscopy of a single lesion suspected to be skin cancer...
January 1, 2018: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/29933390/impact-of-inherent-aspects-of-body-image-eating-behavior-and-perceived-health-competence-on-quality-of-life-of-university-students
#8
Wanderson Roberto da Silva, Juliana Alvares Duarte Bonini Campos, João Marôco
The aim of this study was to assess the impact of inherent aspects of body image, eating behavior and perceived health competence on quality of life of university students. Participants completed the instruments Body Shape Questionnaire (reduced version, BSQ-8B), Male Body Dissatisfaction Scale (reduced version, MBDS-R), Three-Factor Eating Questionnaire (reduced version, TFEQ-18), Perceived Health Competence Scale (bifactorial version, PHCS-B), World Health Organization Quality of Life Questionnaire-Short Form (WHOQoL-bref) and a questionnaire for characterization of sample...
2018: PloS One
https://www.readbyqxmd.com/read/29933089/new-technology-for-surgical-treatment-of-osteoporotic-vertebral-compression-fractures-the-transvertebral-bone-graft-and-fixation
#9
Yang Hou, Jingchuan Sun, Jiangang Shi, Guodong Shi, Guohua Xu, Yongfei Guo, Dan Han
OBJECTIVE: To introduce an innovative surgical technique named as trans-vertebral bone graft and augmentation(TBGA) and evaluate its clinical efficacy with balloon Kyphoplasty (BKP) as control for osteoporotic VCFs. METHODS: A total of 81 patients with one-level osteoporotic VCFs received the TBGA(n=38) or BKP(n=43) from October 2012 to January 2015. The average follow-up period of the patients was 27.9 months. The patients were evaluated using plain radiographs, computerized tomography and magnetic resonance imaging preoperatively...
June 19, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29932368/pure-arterial-malformation-of-the-posterior-inferior-cerebellar-artery-with-interspersed-adipose-tissue-case-report
#10
Thomas J Sorenson, Waleed Brinjikji, Kelly D Flemming, Giuseppe Lanzino
Incidental vascular lesions are being discovered at an increasing frequency due to widespread noninvasive brain imaging studies. One of these lesions has recently been termed a "pure arterial malformation" (PAM), which is defined as dilated, overlapping, and tortuous arteries forming a mass of arterial loops with a coil-like appearance in the absence of arteriovenous shunting. The pathogenesis of these lesions is not known, but a congenital etiology is suspected. The authors report the case of a 17-year-old female who was found to have a PAM of the posterior inferior cerebellar artery with adipose tissue interspersed within the arterial loops...
June 22, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29932244/tumor-targeting-salmonella-typhimurium-a1-r-arrests-a-doxorubicin-resistant-pdgfra-amplified-patient-derived-orthotopic-xenograft-mouse-model-of-pleomorphic-liposarcoma
#11
Tasuku Kiyuna, Yasunori Tome, Takashi Murakami, Ming Zhao, Kentaro Miyake, Kentaro Igarashi, Kei Kawaguchi, Masuyo Miyake, Hiromichi Oshiro, Takashi Higuchi, Yunfeng Li, Sarah M Dry, Scott D Nelson, Tara A Russell, Mark A Eckardt, Arun S Singh, Fuminori Kanaya, Fritz C Eilber, Robert M Hoffman
Pleomorphic liposarcoma (PLPS) is a recalcitrant soft-tissue sarcoma (STS) subtype in need of transformative therapy. We have previously established a patient-derived orthotopic xenograft (PDOX) model, of PLPS with PDGFRA amplification, using surgical orthotopic implantation. In the current study, the PLPS PDOX model was randomized into 3 groups of 7 mice each: untreated control; doxorubicin (DOX)-treated; and treated with Salmonella typhimurium A1-R (S. typhimurium A1-R) expressing green fluorescent protein (GFP)...
June 22, 2018: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29932160/solitary-brain-mass-in-a-patient-with-seizures-an-unexpected-infectious-etiology
#12
Mohammed Raja, Jose Armando Gonzales Zamora, Ali Hassoun
Neurocysticercosis is a parasitosis caused by the larval stage of the pork tapeworm Taenia solium. The diagnosis is challenging as morphology on neuroimaging can be inconclusive and serology is frequently negative. We describe the case of a 24-year old Hispanic man who presented with seizures and loss of consciousness. Magnetic resonance imaging (MRI) showed a cystic mass in right frontal lobe. Work-up that included body computed tomography (CT) scan and Western blot serology for Echinococcus and cysticercosis was unrevealing...
June 22, 2018: Diseases (Basel)
https://www.readbyqxmd.com/read/29931753/turning-toxicants-into-safe-therapeutic-drugs-cytolytic-peptide-photosensitizer-assemblies-for-optimized-in-vivo-delivery-of-melittin
#13
Hao-Ran Jia, Ya-Xuan Zhu, Ke-Fei Xu, Fu-Gen Wu
Melittin (MEL) is recognized as a highly potent therapeutic peptide for treating various human diseases including cancer. However, the clinical applications of MEL are largely restricted by its severe hemolytic activity and nonspecific cytotoxicity. Here, it is found that MEL can form a stable supramolecular nanocomplex of ≈60 nm with the photosensitizer chlorin e6 (Ce6), which after hyaluronic acid (HA) coating can achieve robust, safe, and imaging-guided tumor ablation. The as-designed nanocomplex (denoted as MEL/Ce6@HA) shows largely reduced hemolysis and selective cytolytic activity toward cancer cells...
June 21, 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29931685/body-image-concerns-in-patients-with-an-implantable-cardioverter-defibrillator-a-scoping-review
#14
REVIEW
Vivi S Frydensberg, Søren J Skovbakke, Susanne S Pedersen, Robin N Kok
BACKGROUND: Patients with an implantable cardioverter defibrillator (ICD) retain a scar and a bump at the site of implant. This may lead to body image concerns (BICs) that influence patients' quality of life. Few studies have examined the prevalence and impact of BICs post implant, prompting us to conduct a scoping review of the field. METHODS: We searched the Medline, Embase, PsycINFO and Cinahl databases in August 2016 and repeated May 2017. Included were studies reporting on patients ≥ 18 years, an ICD implant (transvenous, subcutaneous, or ICD with cardiac resynchronization therapy (CRT-D), reporting on BICs, and published in peer-reviewed English-language journals...
June 22, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29931431/imaging-cobalamin-uptake-within-malignant-breast-tumors-in-vivo
#15
Douglas A Collins
PURPOSE: To image the uptake of cobalamin (Cbl) within malignant breast tumors in vivo. PROCEDURES: Prior to surgery 20 female patients with clinically suspected breast tumors were intravenously administered 0.25 μg of an In-111 labeled 5-deoxyadenosylcobalamin (AC) analog ([111 In]AC) and sequentially imaged with whole-body planar (WBP) and single-photon emission computed tomography (SPECT) between 2-5 h and 20-24 h post-injection (P.I.). The tumor to background (T/B) ratio for [111 In]AC in breast tumors at 2-5 h was correlated to its expression of estrogen (ER), progesterone (PR), and human epidermal growth factor 2 (HER2) receptors...
June 21, 2018: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/29931314/scip-a-single-cell-image-processor-toolbox
#16
Leonardo Martins, Ramakanth Neeli-Venkata, Samuel M D Oliveira, Antti Häkkinen, Andre S Ribeiro, José M Fonseca
Summary: Each cell is a phenotypically unique individual that is influenced by internal and external processes, operating in parallel. To characterize the dynamics of cellular processes one needs to observe many individual cells from multiple points of view and over time, so as to identify commonalities and variability. With this aim, we engineered a software, "SCIP", to analyse multi-modal, multi-process, time-lapse microscopy morphological and functional images. SCIP is capable of automatic and/or manually corrected segmentation of cells and lineages, automatic alignment of different microscopy channels, as well as detect, count and characterize fluorescent spots (such as RNA tagged by MS2-GFP), nucleoids, Z rings, Min system, inclusion bodies, undefined structures, etc...
June 21, 2018: Bioinformatics
https://www.readbyqxmd.com/read/29931096/association-of-biological-markers-of-alcohol-consumption-and-self-reported-drinking-with-hippocampal-volume-in-a-population-based-sample-of-adults
#17
Andrew Naglich, Erin Van Enkevort, Bryon Adinoff, E Sherwood Brown
Aims: The current study examined a large community cohort to understand relationships between indicators of alcohol consumption and hippocampal volume. Short summary: Alcohol use measures were not associated with hippocampal volume in a population-based sample. However, alcohol consumption was associated with hippocampal volume reduction in subsets of the sample including subjects aged ≥50 years old, and those with none to moderate levels of depressive symptoms...
June 21, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/29931068/serum-25-hydroxyvitamin-d-concentrations-are-associated-with-computed-tomography-markers-of-subclinical-interstitial-lung-disease-among-community-dwelling-adults-in-the-multi-ethnic-study-of-atherosclerosis-mesa
#18
Samuel M Kim, Di Zhao, Anna J Podolanczuk, Pamela L Lutsey, Eliseo Guallar, Steven M Kawut, R Graham Barr, Ian H de Boer, Bryan R Kestenbaum, David J Lederer, Erin D Michos
Background: Activated vitamin D has anti-inflammatory properties. 25-Hydroxyvitamin D [25(OH)D] deficiency might contribute to subclinical interstitial lung disease (ILD). Objective: We examined associations between serum 25(OH)D concentrations and subclinical ILD among middle-aged to older adults who were free of cardiovascular disease at baseline. Methods: We studied 6302 Multi-Ethnic Study of Atherosclerosis (MESA) participants who had baseline serum 25(OH)D concentrations and computed tomography (CT) imaging spanning ≤ 10 y...
June 19, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29930476/traditional-and-confocal-descriptions-of-a-new-genus-and-two-new-species-of-deep-water-cerviniinae-sars-1903-from-the-southern-atlantic-and-the-norwegian-sea-with-a-discussion-on-the-use-of-digital-media-in-taxonomy-copepoda-harpacticoida-aegisthidae
#19
Paulo H C Corgosinho, Terue C Kihara, Nikolaos V Schizas, Alexandra Ostmann, Pedro Martínez Arbizu, Viatcheslav N Ivanenko
Aegisthidae is one of the most abundant and diverse families of harpacticoid copepods living in deep-sea benthos, and the phylogenetic relationships within the family are in state of flux. Females of two new deep-water species of harpacticoid copepods belonging to the Hase gen. n. (Aegisthidae: Cerviniinae) are described. The first taxonomic description of marine copepod species based on the combined use of interference and confocal microscopy for the study of the habitus and dissected appendages is presented here...
2018: ZooKeys
https://www.readbyqxmd.com/read/29930452/distinguishing-midzonal-iris-pigment-epithelial-cyst-from-adenoma-and-ciliary-body-melanoma
#20
Eileen L Mayro, Thamolwan Surakiatchanukul, Jerry A Shields, Carol L Shields
A 49-year old male with corrected visual acuity of 20/25 OD and 20/20 OS was found to have an asymptomatic dark iris mass OD with suspicion for ciliary body melanoma. Predilation slit-lamp biomicroscopy revealed a well-circumscribed brown round mass arising posterior to the iris, presumably from the ciliary body; however, postdilation demonstrated an extended fusiform mass of the iris pigment epithelium (IPE). By anterior segment imaging, the well-circumscribed IPE mass was cystic and measured 1440 microns in thickness peripherally predilation and 300 microns in thickness postdilation...
May 2018: Oman Journal of Ophthalmology
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