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JOURNAL ARTICLE
Amir Yari, Paniz Fasih, Mohammad Hosseini Hooshiar, Ali Goodarzi, Seyedeh Farnaz Fattahi
PURPOSE: This study aimed to assess the performance of a deep learning algorithm (YOLOv5) in detecting different mandibular fracture types in panoramic images. METHODS: This study utilized a dataset of panoramic radiographic images with mandibular fractures. The dataset was divided into training, validation, and testing sets, with 60%, 20%, and 20% of the images, respectively. An equal number of control panoramic radiographs, which did not contain any fractures, were also randomly distributed among the three sets...
April 23, 2024: Dento Maxillo Facial Radiology
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JOURNAL ARTICLE
Anna Faivre, Milica Bugarski, Anna Rinaldi, Imene B Sakhi, Thomas Verissimo, David Legouis, Sara Correia, Monika Kaminska, Delal Dalga, Daniele Malpetti, Pietro E Cippa, Sophie de Seigneux, Andrew M Hall
BACKGROUND: Large increases in glomerular protein filtration induce major changes in body homeostasis and increase risk of kidney functional decline and cardiovascular disease. We investigated how elevated protein exposure modifies the landscape of tubular function along the entire nephron, to understand the cellular changes that mediate these important clinical phenomena. METHODS: We conducted single nuclei RNA sequencing, functional intravital imaging, and antibody staining to spatially map transport processes along the mouse kidney tubule...
April 24, 2024: Journal of the American Society of Nephrology: JASN
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JOURNAL ARTICLE
Hannah Oh, Lusine Yaghjyan, Yujing J Heng, Bernard Rosner, Matt B Mahoney, Divya Murthy, Gabrielle M Baker, Rulla M Tamimi
BACKGROUND: According to the stem cell hypothesis, breast carcinogenesis may be related to the breast stem cell pool size. However, little is known about associations of breast cancer risk factors, such as anthropometric measures, with the expression of stem cell markers in non-cancerous breast tissue. METHODS: The analysis included 414 women with biopsy-confirmed benign breast disease (BBD) in the Nurses' Health Study (NHS) and NHSII. Birthweight, weight at age 18, current weight, and current height were reported via self-administered questionnaire...
April 23, 2024: Cancer Epidemiology, Biomarkers & Prevention
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REVIEW
Stephanie M Yoon, Jose G Bazan
PURPOSE: We examine the potential for curative approaches among metastatic breast cancer (MBC) patients by exploring the recent literature on local ablative therapies like surgery and stereotactic body radiation therapy (SBRT) in patients with oligometastatic (OM) breast cancer. We also cover therapies for MBC patients with oligoprogressive (OP) disease. KEY FINDINGS: Surgery and SBRT have been studied for OM and OP breast cancer, mainly in retrospective or non-randomized trials...
April 23, 2024: Current Oncology Reports
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MULTICENTER STUDY
José Luis Rodicio Miravalles, Carlos San Miguel Méndez, Javier Lopez-Monclus, María Moreno Gijón, Patricia López Quindós, Sonia Amoza Pais, Antonio López López, Isabel García Bear, Rafael Menendez de Llano Ortega, María Isabel Díez Pérez de Las Vacas, Miguel Angel Garcia-Urena
INTRODUCTION: Prophylactic meshes in high-risk patients prevent incisional hernias, although there are still some concerns about the best layer to place them in, the type of fixation, the mesh material, the significance of the level of contamination, and surgical complications. We aimed to provide answers to these questions and information about how the implanted material behaves based on its visibility under magnetic resonance imaging (MRI). METHOD: This is a prospective multicentre observational cohort study...
April 23, 2024: Langenbeck's Archives of Surgery
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JOURNAL ARTICLE
Enrico G Italiano, Francesco Bertelli, Irene Cao, Raffaella Motta, Giovanni Di Salvo, Vladimiro Vida, Massimo A Padalino
The current use of intracorporeal left ventricular assist devices in children is still limited by small body dimensions. Many children weighing of less than 30 kg requiring durable mechanical circulatory support are implanted with the Berlin Heart EXCOR, a paracorporeal device. We present the case of a girl aged 10 years with a body surface area of 1.01 m2 undergoing a safe and effective HeartMate3 implantation despite extremely small thoracic dimensions. Using computed tomography-derived three-dimensional (3D) reconstruction, it was possible to simulate several device positions finding the best HeartMate3 lodging...
October 19, 2023: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
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JOURNAL ARTICLE
Zhenglin Pan, Na Qi, Qingyuan Meng, Boyang Pan, Tao Feng, Jun Zhao, Nan-Jie Gong
BACKGROUND: The application of deep learning methods in rapid bone scintigraphy is increasingly promising for minimizing the duration of SPECT examinations. Recent works showed several deep learning models based on simulated data for the synthesis of high-count bone scintigraphy images from low-count counterparts. Few studies have been conducted and validated on real clinical pairs due to the misalignment inherent in multiple scan procedures. PURPOSE: To generate high quality whole-body bone images from 2× and 3× fast scans using deep learning based enhancement method...
April 23, 2024: Medical Physics
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JOURNAL ARTICLE
Katerina Deike, Andreas Decker, Paul Scheyhing, Julia Harten, Nadine Zimmermann, Daniel Paech, Oliver Peters, Silka D Freiesleben, Luisa-Sophie Schneider, Lukas Preis, Josef Priller, Eike Spruth, Slawek Altenstein, Andrea Lohse, Klaus Fliessbach, Okka Kimmich, Jens Wiltfang, Claudia Bartels, Niels Hansen, Frank Jessen, Ayda Rostamzadeh, Emrah Düzel, Wenzel Glanz, Enise I Incesoy, Michaela Butryn, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H Munk, Annika Spottke, Nina Roy, Michael Wagner, Sandra Roeske, Michael T Heneka, Frederic Brosseron, Alfredo Ramirez, Laura Dobisch, Steffen Wolfsgruber, Luca Kleineidam, Renat Yakupov, Melina Stark, Matthias C Schmid, Moritz Berger, Stefan Hetzer, Peter Dechent, Klaus Scheffler, Gabor C Petzold, Anja Schneider, Alexander Effland, Alexander Radbruch
OBJECTIVES: Impaired perivascular clearance has been suggested as a contributing factor to the pathogenesis of Alzheimer disease (AD). However, it remains unresolved when the anatomy of the perivascular space (PVS) is altered during AD progression. Therefore, this study investigates the association between PVS volume and AD progression in cognitively unimpaired (CU) individuals, both with and without subjective cognitive decline (SCD), and in those clinically diagnosed with mild cognitive impairment (MCI) or mild AD...
April 23, 2024: Investigative Radiology
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JOURNAL ARTICLE
Benjamin Harris Peterson Corman, Alexander Bjorling, Huseyin Isildak
Fishbone foreign body (FFB) can lodge in the upper respiratory or gastrointestinal tracts and frequently cause discomfort. While FFBs are common, variations in the hyoid may present radiographically similarly. The authors present a case in which a 32-year-old woman presented with pain in the right neck with a globus sensation after eating fish. Examination, including flexible fiberoptic laryngoscopy, did not reveal a foreign body. Given the patients' persistent symptoms, a noncontrast computed tomography was performed, demonstrating a radiopaque body superior to the right lateral hyoid bone, consistent with FFB...
April 23, 2024: Journal of Craniofacial Surgery
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JOURNAL ARTICLE
Kshipra S Kapoor, Seoyun Kong, Hikaru Sugimoto, Wenhua Guo, Vivek Boominathan, Yi-Lin Chen, Sibani Lisa Biswal, Tanguy Terlier, Kathleen M McAndrews, Raghu Kalluri
Evaluating the heterogeneity of extracellular vesicles (EVs) is crucial for unraveling their complex actions and biodistribution. Here, we identify consistent architectural heterogeneity of EVs using cryogenic transmission electron microscopy (cryo-TEM), which has an inherent ability to image biological samples without harsh labeling methods while preserving their native conformation. Imaging EVs isolated using different methodologies from distinct sources, such as cancer cells, normal cells, immortalized cells, and body fluids, we identify a structural atlas of their dominantly consistent shapes...
April 23, 2024: ACS Nano
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JOURNAL ARTICLE
Yukun Cao, Hua Peng, Kailu Zhang, Mengting Huang, Qinyue Luo, Hanting Li, Yumin Li, Lin Wang, Heshui Shi
BACKGROUND: Cardiovascular magnetic resonance (cardiac MR) reference ranges in Chinese children are lacking. PURPOSE: To establish age- and sex-specific reference ranges for cardiac MR parameters in a cohort of healthy Chinese children. STUDY TYPE: Retrospective. SUBJECTS: One hundred ninety-six healthy children (mean age 9.5 ± 3.6 years, 111 boys). FIELD STRENGTH/SEQUENCE: 1...
April 23, 2024: Journal of Magnetic Resonance Imaging: JMRI
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JOURNAL ARTICLE
Continuous Shear Wave Elastography for Liver Using Frame-to-Frame Equalization of Complex Amplitude.
Naoki Tano, Ren Koda, Shunichiro Tanigawa, Naohisa Kamiyama, Yoshiki Yamakoshi, Marie Tabaru
This study addresses a crucial necessity in the field of noninvasive liver fibrosis diagnosis by introducing the concept of continuous shear wave elastography (C-SWE), utilizing an external vibration source and color Doppler imaging. However, an application of C-SWE to assess liver elasticity, a deep region within the human body, arises an issue of signal instability in the obtained data. To tackle this challenge, this work proposes a method involving the acquisition of multiple frames of datasets, which are subsequently compressed...
April 23, 2024: Ultrasonic Imaging
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JOURNAL ARTICLE
Gerasimos Terzis, Eftychia Vekaki, Constantinos Papadopoulos, Giorgos Papadimas, Angeliki-Nikoletta Stasinaki
Ultrasonography has been extensively used to evaluate skeletal muscle morphology. The echo intensity, i.e., the mean pixel intensity of a specific region of interest in an ultrasound image, may vary among muscles and individuals with several intramuscular parameters presumed to influence it. The purpose of this study was to investigate the correlation between muscle echo intensity and muscle fiber type composition in humans. Thirteen female physical education students (age: 22.3 ± 5.4 years, height: 1...
April 5, 2024: Journal of Functional Morphology and Kinesiology
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JOURNAL ARTICLE
Anna Jalo, Jatta S Helin, Jaakko Hentilä, Tuuli A Nissinen, Sanna M Honkala, Marja A Heiskanen, Eliisa Löyttyniemi, Tarja Malm, Jarna C Hannukainen
Recent studies have shown that obesity and insulin resistance are associated with increased insulin-stimulated glucose uptake (GU) in the brain. Thus, insulin sensitivity seems to work differently in the brain compared to the peripheral tissues like skeletal muscles, but the underlying mechanisms remain unknown. Regular exercise training improves skeletal muscle and whole-body insulin sensitivity. However, the effect of exercise on glucose metabolism in the brain and internal organs is less well understood...
March 25, 2024: Journal of Functional Morphology and Kinesiology
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JOURNAL ARTICLE
Roman Alvarado, Ulrich M Scheven, Jens-Christian Meiners
PURPOSE: To observe the growth and resolution of decompression gas bubbles in the spinal cord of live rats in real time using MRI. METHODS: We constructed an MRI-compatible pressure chamber system to visualize gas bubble dynamics in deep tissues in real time. The system pressurizes and depressurizes rodents inside an MRI scanner and monitors their respiratory rate, heart rate, and body temperature while providing gaseous anesthesia under pressure during the experiments...
April 23, 2024: Magnetic Resonance in Medicine
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JOURNAL ARTICLE
Richard R A Syms, Christopher A Wadsworth, Evdokia Kardoulaki, Attapol Titapun, Wuttisak Boonphongsathien, Prakasit Sa-Ngiamwibool, Shuo Zhang, Simon D Taylor-Robinson, Nittaya Chamadol, Watcharin Loilome
Intraductal T2 mapping based on a catheter receiver is proposed as a method of visualizing the extent of intraductal and periductal cholangiocarcinoma (CCA). Compared to external receivers, internal receivers provide locally enhanced signal-to-noise ratios by virtue of their lower field-of-view for body noise, allowing smaller voxels and higher resolution. However, inherent radial sensitivity variation and segmentation for patient safety both distort image brightness. We discuss simulated T2 weighted images and T2 maps, and in vitro images obtained using a thin film catheter receiver of a freshly resected liver specimen containing a polypoid intraductal tumor from a patient with CCA...
2024: Frontiers in Oncology
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JOURNAL ARTICLE
David Mummy, Shuo Zhang, Aryil Bechtel, Junlan Lu, Joseph Mammarappallil, Suphachart Leewiwatwong, Anna Costelle, Aparna Swaminathan, Bastiaan Driehuys
INTRODUCTION: Hyperpolarized 129 Xe MRI and spectroscopy is a rapidly growing technique for assessing lung function, with applications in a wide range of obstructive, restrictive, and pulmonary vascular disease. However, normal variations in 129 Xe measures of gas exchange across healthy subjects are not well characterized, presenting an obstacle to differentiating disease processes from the consequences of expected physiological heterogeneity. Here, we use multivariate models to evaluate the role of age, sex, and BMI in a range of commonly used 129 Xe measures of gas exchange...
2024: Frontiers in Medicine
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JOURNAL ARTICLE
Tayebeh Sasanfar, Raziyeh Maasoumi, Mina Ataei, Shima Haghani, Maryam Nekoolaltak
BACKGROUND: Despite the increasing growth of female genital cosmetic procedures, the long-term effects of these procedures are not clearly understood. This study was conducted to compare the genital self-image and sexual function in women with and without female genital cosmetic procedures. METHODS: This cross-sectional study was conducted on 315 participants (210 women without a history of genital cosmetic surgery and 105 women with it) in Alborz province, Iran, from early February 2023 to mid-May 2023...
April 2024: International Journal of Community Based Nursing and Midwifery
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JOURNAL ARTICLE
Teiko Takedai, Nicole Block, Karina M Pinal, Steven W Frederick
INTRODUCTION: Acute thoracolumbar intervertebral disc herniation (IVDH) constitutes an emergency because associated neurological clinical signs can be progressive, with prognosis dependent on preoperative presence of deep pain perception. Pre-anesthetic thoracic radiographs are routinely performed to evaluate for potential pathology that could result in increased risk or change in overall prognosis. However, due to the emergent nature of this disease, the weight of thoracic radiographic findings on treatment plans for these dogs in unknown...
2024: Frontiers in Veterinary Science
#20
Hassan Hussain, Chaminda Janaka, Anne Sonali Rodrigo, Manojkumar Krishnan, Azra Hassan
Non-Hodgkin's lymphomas (NHLs) are a group of lymphoproliferative diseases that originate from different cell types, namely B cells, T cells, or natural killer cells. Herein, we report the case of a 69-year-old male patient who presented with a gradual-onset, intermittent, low-grade fever for four months and a right-sided neck lump for two months. On examination, a right-sided enlarged lymph node sized 1 × 1 cm2 was noted, which was mobile, hard in consistency, and non-tender. No other lymphadenopathy was noted in other parts of the body...
March 2024: Curēus
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