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https://www.readbyqxmd.com/read/29774938/-analysis-of-risk-factors-of-prolonged-postoperative-ileus-after-gastric-cancer-surgery
#1
Ning Wang, Lin Chen, Mingsen Li, Naizhong Jin, Bo Wei
OBJECTIVE: To investigate the risk factors of prolonged postoperative ileus (PPOI) after gastric cancer surgery. METHODS: Definition of PPOI was that gastrointestinal function did not return to normal within 96 hours after operation. Diagnostic criteria of PPOI were as follows: according with over 2 below conditions at postoperative 97-hour: (1) moderate to severe sick (mild: 1-3 points, moderate: 4-7 points, severe: 8-10 points) or vomiting occurred in past 12 hours...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29763594/patient-controlled-paravertebral-block-for-video-assisted-thoracic-surgery-a-randomized-trial
#2
Zixiang Wu, Shuai Fang, Qi Wang, Cong Wu, Tianwei Zhan, Ming Wu
BACKGROUND: Paravertebral block (PVB) has been proven to be an efficient way to control postoperative pain in patients who have undergone a thoracotomy. This study aimed to explore whether the utilization of a patient-controlled PVB can provide benefits over intravenous patient-controlled analgesia (PCA) for three-port single-intercostal video-assisted thoracic surgery. METHODS: From May 2015 to December 2016, patients who had solitary pulmonary nodules or spontaneous pneumothorax and underwent single-intercostal video-assisted thoracic surgery were randomly allocated to receive patient-controlled PVB or intravenous PCA...
May 12, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29740688/the-safety-and-efficacy-of-oxycodone-versus-fentanyl-in-percutaneous-microwave-ablation-of-a-liver-tumour-abutting-the-capsule
#3
Wen-Tao Wu, Zhen-Yu Jia, Yu Chen, Qi-Feng Chen, Qing-Quan Zu, Zheng-Qiang Yang, Sheng Liu, Hai-Bin Shi
PURPOSE: The present study compared the safety and efficacy of oxycodone with those of fentanyl under non-intubated general anaesthesia in percutaneous microwave ablation (MWA) of a liver tumour abutting the capsule. MATERIALS AND METHODS: Thirty-eight patients underwent MWA of liver cancers abutting the capsule. Patients received 0.1 mg/kg oxycodone (O group) or 1 μg/kg fentanyl (F group) prior to the start of ablation. Both groups received continuous infusions of propofol for non-intubated general anaesthesia during ablation...
May 8, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29701042/-effects-of-transcutaneous-electrical-acupoint-stimulation-on-quality-of-recovery-during-early-period-after-laparoscopic-cholecystectomy
#4
Zhihua Mi, Ju Gao, Xiaoping Chen, Yali Ge, Kaixin Lu
OBJECTIVE: To evaluate the effect of transcutaneous electrical acupoint stimulation (TEAS) on the quality of recovery during the early period after laparoscopic cholecystectomy and the dosage of anesthetic and analgesic. METHODS: One hundred patients who received laparoscopic cholecystectomy with gradeⅠand Ⅱ of American Society of Anesthesiologists (ASA) criteria were randomly assigned into an observation group and a control group according to random number table, 50 cases in each group...
March 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29624527/dezocine-alleviates-morphine-induced-dependence-in-rats
#5
Fei-Xiang Wu, Hasan Babazada, Hao Gao, Xi-Ping Huang, Chun-Hua Xi, Chun-Hua Chen, Jin Xi, Wei-Feng Yu, Renyu Liu
BACKGROUND: Opioid dependence is a major public health issue without optimal therapeutics. This study investigates the potential therapeutic effect of dezocine, a nonaddictive opioid, in opioid dependence in rat models. METHODS: Dezocine was administered intraperitoneally to a morphine-dependent rat model to investigate its effect on withdrawal and conditioned place preference (CPP). Effect of dezocine on morphine withdrawal syndrome and CPP was analyzed using 2-way analysis of variance (ANOVA) followed by Tukey's post hoc test...
April 5, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29416260/intravenous-dezocine-for-suppressing-fentanyl-induced-cough-during-general-anesthesia-induction-a-potentially-effective-and-clinically-feasible-method
#6
Aria Soleimani, Farshad Hasanzadeh Kiabi, Mohammad Reza Habibi, Amir Emami Zeydi, Abdolghader Assarroudi, Hassan Sharifi
No abstract text is available yet for this article.
October 2017: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/29399191/effects-of-flurbiprofen-on-serum-level-of-interleukin-6-prostacyclin-and-corticosteroid-a2-in-patients-with-bone-metastases-of-cancer
#7
Yanwei Yin, Yusheng Yi, Junmin Yu, Xiuming Sun, Chuansheng Liu, Fenghe Xu
The present study aimed to investigate the effects of flurbiprofen on serum level of interleukin-6 (IL-6), prostacyclin (PGI2) and corticosteroid A2 (TXA2) in patients with bone metastases of cancer. A total of 210 patients with bone metastasis of cancer were randomly divided into two groups: Flurbiprofen axetil analgesia group (group A) and dezocine analgesia group (group B), 105 cases in each group. The analgesic effect was evaluated using visual analogue scale (VAS) scoring system at 1, 12, 24 and 48 h after treatment...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29325337/-the-application-of-combining-low-dose-naloxone-with-ropivacaine-in-supraclavicular-brachial-plexus-block
#8
J Tang, S Y Zhang, F J Lu, W H Qin, Y S Shi
Objective: To observe the effect of low dose naloxone combinewith ropivacaine for supraclavicular brachial plexus block. Methods: Seventy patients undergoing elective upper limb surgery were randomly divided into two groups, ropivacaine group (Group R, n =35) and naloxone group (Group N, n =35). An ultrasound guided technique was used in both two groups.The onset and duration time of sensory and motor blockade, visual analog score(VAS)of 3, 6, 12, 18, 24 h postoperatively, time of first request fordezocine, total amount of dezocine needed, incidence of nausea and vomiting postoperatively(PONV) and patients' satisfaction score for analgesia in 24 h after surgery were measured...
December 26, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29246707/reprint-of-efficacy-and-safety-of-different-doses-of-dezocine-for-preemptive-analgesia-in-gynecological-laparoscopic-surgeries-a-prospective-double-blind-and-randomized-controlled-clinical-trial
#9
Meiyan Zhou, Liwei Wang, Congyou Wu, Li Yan, Rongguo Wang, Bin Sun, Jianhua Wang
BACKGROUND: The incidence of reproductive system tumors in Chinese females is increasing year by year, with the trend of younger onset ages. Laparoscopic surgery has been recognized by the majority of medical staff and patients, but the postoperative pain still exists. Therefore, it has become the focus of attention of medical workers to take effective analgesia measures to alleviate postoperative pain as well as to improve the degree of comfort and satisfaction for the patients. OBJECTIVES: The research objective was to study the effect of different doses of dezocine preemptive analgesia on the safety and the pain post laparoscopic surgeries, in order to explore the best dose of dezocine for postoperative analgesia in gynecological laparoscopic surgeries...
January 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29228438/analgesic-effect-of-dezocine-in-different-doses-on-elderly-patients-undergoing-abdominal-operation-under-general-anesthesia-and-its-influence-on-stress-response-to-postoperative-tracheal-extubation
#10
Z-Y Yao, Z Jia, Y-H Xie, L-L Zhang, H-S Zhang, W-Q Wu, C-K Zhang, L-J Gan
OBJECTIVE: To study the analgesic effect of dezocine in different doses on elderly patients undergoing abdominal operation under general anesthesia and to investigate the influence of dezocine on stress response to postoperative tracheal extubation. PATIENTS AND METHODS: A total of 76 elderly patients undergoing abdominal operation under general anesthesia and postoperative analgesia in our hospital from January 2015 to January 2016 were selected, and patients treated with fentanyl were selected as the control group (fentanyl: 10 μg/kg, n=19)...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29191264/the-effect-of-dezocine-pretreatment-on-dexamethasone-induced-perineal-irritation
#11
LETTER
Junwei Zheng, Yonghai Zhang, Yang Gu, Fan Yang, Hanxiang Ma
No abstract text is available yet for this article.
February 2018: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29166854/a-single-dose-of-dezocine-suppresses-emergence-agitation-in-preschool-children-anesthetized-with-sevoflurane-remifentanil
#12
Li-Jun An, Yang Zhang, Zheng Su, Xian-Long Zhang, Hai-Lin Liu, Zhi-Jie Zhang, Jian-Lin Hu, Shi-Tong Li
BACKGROUND: Emergence agitation (EA) is a common phenomenon in preschool children during emergence from general anesthesia. This study evaluated the safety and efficacy of dezocine for emergence agitation in preschool children anesthetized with sevoflurane-remifentanil. METHODS: A total of 100 preschool children, scheduled for elective laparoscopic repair of an inguinal hernia by high ligation of the hernia sac under sevoflurane-remifentanil anesthesia were randomized into two groups: Group C (n = 50) received Ringer's lactate 10 mL and Group D received Ringer's lactate 10 mL containing dezocine 0...
November 22, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/29097325/efficacy-and-safety-of-different-doses-of-dezocine-for-preemptive-analgesia-in-gynecological-laparoscopic-surgeries-a-prospective-double-blind-and-randomized-controlled-clinical-trial
#13
Meiyan Zhou, Liwei Wang, Congyou Wu, Li Yan, Rongguo Wang, Bin Sun, Jianhua Wang
BACKGROUND: The incidence of reproductive system tumors in Chinese females is increasing year by year, with the trend of younger onset ages. Laparoscopic surgery has been recognized by the majority of medical staff and patients, but the postoperative pain still exists. Therefore, it has become the focus of attention of medical workers to take effective analgesia measures to alleviate postoperative pain as well as to improve the degree of comfort and satisfaction for the patients. OBJECTIVES: The research objective was to study the effect of different doses of dezocine preemptive analgesia on the safety and the pain post laparoscopic surgeries, in order to explore the best dose of dezocine for postoperative analgesia in gynecological laparoscopic surgeries...
January 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28864688/effect-of-propofol-combined-with-opioids-on-cough-reflex-suppression-in-gastroscopy-study-protocol-for-a-double-blind-randomized-controlled-trial
#14
Ning Yin, Jiangyan Xia, Yi-Zhi Cao, Xinjian Lu, Jing Yuan, Jue Xie
INTRODUCTION: The best methods for inducing analgesia and sedation for gastroscopy are still debated but finding an adequate regimen of sedation/analgesia is important. Stimulation of the larynx under sedation can cause reflex responses. Propofol with opioids has been recommended for gastroscopy sedation but the effects on cough reflex suppression remain unclear. This trial will evaluate the effects of propofol combined with small doses of dezocine, oxycodone, sufentanil or fentanyl for gastroscopy...
September 1, 2017: BMJ Open
https://www.readbyqxmd.com/read/28858135/stability-study-of-dezocine-in-0-9-sodium-chloride-solutions-for-patient-controlled-analgesia-administration
#15
Bao-Xia Fang, Lin-Hai Wang, Hui-Min Liu, Fu-Chao Chen, Jing Liu
BACKGROUND: Dezocine, a mixed agonist/antagonist of opioid receptors, has been used in iv patient-controlled analgesia (PCA) pumps for postoperative pain control. The aim of this study was to investigate the physicochemical stability of dezocine solutions in 0.9% sodium chloride for injection for PCA administration. METHODS: Solutions of dezocine (0.3, 0.45, or 0.6 mg/mL in 0.9% sodium chloride for injection) were stored in polyolefin bags and glass bottles. Their stabilities at storage conditions of 4°C for 14 days and 25°C for 72 hours were studied...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28761332/using-dezocine-to-prevent-etomidate-induced-myoclonus-a-meta-analysis-of-randomized-trials
#16
Yu Zhu, Yuting Yang, Chengmao Zhou, Zeqing Bao
OBJECTIVE: This study was designed to evaluate the efficacy and safety of preinjection of dezocine in preventing etomidate-induced myoclonus. METHODS: PubMed, Embase, The Cochrane Library, and China National Knowledge Infrastructure (CNKI) were searched to collect relevant randomized controlled trials (RCTs) from inception to July 2016 on the preinjection of dezocine in preventing etomidate-induced myoclonus. Two researchers independently screened literature, extracted data, and evaluated bias risks in accordance with inclusion and exclusion criteria, and then used RevMan 5...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28671091/research-on-dezocine-in-peritoneal-gynecology-operation-under-the-target-organ-effect
#17
Song Lili, Zhao Song
This paper was aimed to further analyze the concrete clinical efficacy of dezocine as an anesthetic for peritoneal gynecology operation and to offer a scientific guidance for future surgical treatments. This paper randomly selected 1000 peritoneal gynecology operation patients in 5 hospitals from January to December 2015 as research objects in the observation group, who were mainly applied with dezocine in operative anesthesia. By analyzing data of cases, it concluded efficacy characteristics of dezocine in various phases, and thus provide scientific guidance for future surgical treatments...
May 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28615968/effects-of-dezocine-on-prevention-of-propofol-injection-pain-a-meta-analysis
#18
REVIEW
Chengmao Zhou, Yuting Yang, Yu Zhu, Lin Ruan
OBJECTIVE: The objective of this study was to evaluate the effects of dezocine on the prevention of propofol injection pain. MATERIALS AND METHODS: We searched for randomized controlled trials (RCTs) of dezocine in preventing propofol injection pain, from inception to April 2016, in PubMed, Embase, Cochrane Library, and CNKI. Next, two reviewers independently screened literature, extracted data, and assessed quality in accordance with the inclusion and exclusion criteria...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28533424/comparison-of-the-efficacy-and-safety-between-dezocine-injection-and-morphine-injection-for-persistence-of-pain-in-chinese-cancer-patients-a-meta-analysis
#19
REVIEW
Lei Wang, Xudong Liu, Jianfeng Wang, Yingjiao Sun, Guozhuan Zhang, Lishuang Liang
The association between the efficacy and safety of dezocine injection and morphine injection for persistence of pain in patients with cancer had yielded controversial results. Therefore, we conduct a meta-analysis of existing observational published studies to assess the relationship between them among Chinese. We conducted a comprehensive research from the databases of PubMed, Web of Science, and Wan Fang Med Online for the related studies up to October 2016. Summary odds ratio (OR) with 95% confidence interval (95% CI) were calculated with the random effects model...
June 30, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28339439/dezocine-antagonizes-morphine-analgesia-upon-simultaneous-administration-in-rodent-models-of-acute-nociception
#20
Na-Na Li, Ya-Qin Huang, Ling-Er Huang, Shao-Hui Guo, Maxwell R Shen, Chen-Ling Guo, Sheng-Mei Zhu, Yong-Xing Yao
BACKGROUND: Dezocine is a powerful analgesic that can be less addictive than morphine, yet how the two drugs interact in vivo is poorly understood. Here we administered dezocine alone or in combination with morphine to different acute nociception paradigms to explore the interactions of the 2 drugs upon co-administration. OBJECTIVE: To evaluate how dezocine interacts with morphine in different acute nociception paradigms. STUDY DESIGN: Laboratory animal study...
March 2017: Pain Physician
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