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https://www.readbyqxmd.com/read/29036027/early-macrophage-infiltration-improves-the-fat-graft-survival-by-inducing-angiogenesis-and-hematopoietic-stem-cell-recruitment
#1
Junrong Cai, Jingwei Feng, Kaiyang Liu, Shaolong Zhou, Feng Lu
BACKGROUND: Fat grafting is a popular soft tissue filler method; however, its results are variable and technique-dependent. Macrophages are present in fat grafts and closely associated with tissue regeneration. We hypothesized that activation/depletion of early macrophages in transferred fat improves/impairs fat graft survival. METHODS: Mouse inguinal fat (~150 mg) was transferred autologously. Fat grafting was first performed without other manipulations to obtain baseline information...
October 12, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29028858/approach-to-the-mature-cosmetic-patient-aging-gracefully
#2
Susan Weinkle, Michael Saco
<p>Aging gracefully has taken on a whole new meaning over the past few decades as new aesthetic treatments have been developed and are becoming more sophisticated by the day. The aging process, which is exacerbated by chronic UV exposure, results in dyspigmentation, loss of skin laxity, precancerous and cancerous skin lesions, fat loss and redistribution, and bone resorption. Laser and light devices can be used to treat dyspigmentation, while neuromodulators and soft tissue fillers can be used for rhytides and revolumization...
June 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29025237/the-role-of-injectables-in-aesthetic-surgery-financial-implications
#3
Bryson G Richards, William F Schleicher, Gehaan F D'Souza, Raymond Isakov, James E Zins
Background: The plastic surgeon competes with both core and noncore physicians and surgeons for traditional cosmetic procedures. In 2007, the American Society for Aesthetic Plastic Surgery (ASAPS) and the American Society of Plastic Surgeons (ASPS) joined efforts to form a Cosmetic Medicine Task Force to further analyze this trend. Objectives: Our objective is to document and quantify the patient capture and total collections generated in a single surgeon's practice exclusive from Botulinum Toxin A and filler injections over a 10-year period...
October 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29025217/use-of-lipotransfer-in-scleroderma
#4
Michelle F Griffin, Aurora Almadori, Peter E Butler
Lipotransfer for soft tissue filling is a well-established plastic and aesthetic surgical technique. Elective fat grafting is considered a safe and well-tolerated procedure. Coleman and others have reported that fat grafting may have tissue regenerative properties and not only serve as a soft tissue filler. There have been reports from our group and others that it may improve fibrosis secondary to many different pathological aetiologies including scleroderma, burn injury, lichen sclerosis, graft vs host disease, and radiation...
July 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28987016/sensitivity-of-aspiration-as-a-safety-test-before-injection-of-soft-tissue-fillers
#5
Jani Aj Van Loghem, James J Fouché, Job Thuis
BACKGROUND: Embolism due to accidental intra-arterial injection of a soft tissue filler (STF) can lead to serious complications. Physicians practice aspiration as a safety test before injection to rule out intra-arterial placement of the needle tip. The value of aspiration as a safety test is evaluated in this study, which also considered the rheological properties of different STFs and their needle dimensions. METHODS: Aspiration with eleven different needle sizes and 24 different STFs was performed using Ringer's lactate (RL) colored with blue skin marking ink and secondly an empty saline bag containing anticoagulated blood, both pressurized to 150 mm Hg to mimic arterial blood pressure...
October 7, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28953747/reply-the-role-of-bacterial-biofilm-in-adverse-soft-tissue-filler-reactions-a-combined-laboratory-and-clinical-study
#6
Anand K Deva
No abstract text is available yet for this article.
October 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28941654/soft-tissue-fillers-for-adipose-tissue-regeneration-from-hydrogel-development-toward-clinical-applications
#7
REVIEW
I Van Nieuwenhove, L Tytgat, M Ryx, P Blondeel, F Stillaert, H Thienpont, H Ottevaere, P Dubruel, S Van Vlierberghe
There is a clear and urgent clinical need to develop soft tissue fillers that outperform the materials currently used for adipose tissue reconstruction. Recently, extensive research has been performed within this field of adipose tissue engineering as the commercially available products and the currently existing techniques are concomitant with several disadvantages. Commercial products are highly expensive and associated with an imposing need for repeated injections. Lipofilling or free fat transfer has an unpredictable outcome with respect to cell survival and potential resorption of the fat grafts...
September 20, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28930789/intracranial-penetration-during-temporal-soft-tissue-filler-injection-is-it-possible
#8
Wolfgang G Philipp-Dormston, Lara Bieler, Mathias Hessenberger, Thilo L Schenck, Konstantin Frank, Johann Fierlbeck, Sebastian Cotofana
BACKGROUND: Treating temporal volume loss for aesthetic and reconstructive purposes can be achieved by superficial or deep injections of soft tissue fillers into the temples. The latter is performed with bone contact that can lead to intracranial penetration when the bone is accidentally penetrated. OBJECTIVE: Based on a clinical case, the potential risk of accidental intracranial penetration was investigated. MATERIALS AND METHODS: Twenty fresh-frozen hemi-faces (all Caucasian ethnicity, 10 women, 10 men, mean age 72...
September 19, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28923273/surgeon-s-guide-to-facial-soft-tissue-filler-injections-relevant-anatomy-and-safety-considerations
#9
REVIEW
Elie M Ferneini, Steven Hapelas, James Watras, Antoine M Ferneini, Drew Weyman, Jenna Fewins
The purpose of this study is to provide a review of the relevant facial anatomy related to soft tissue filler injections. Facial fillers are used daily in our clinical practice. Although their use is safe and predictable, adverse events do occur. Some of these dire events include vascular complications leading to blindness, ischemia, and even stroke. Proper knowledge and understanding of the anatomic landmarks can minimize the risk of these vascular events. In addition, early recognition and treatment are necessary to prevent permanent complications...
August 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28915281/precision-in-dermal-filling-a-comparison-between-needle-and-cannula-when-using-soft-tissue-fillers
#10
Tatjana Pavicic, Konstantin Frank, Katharina Erlbacher, Romy Neuner, Stefan Targosinski, Thilo Schenck, Robert H Gotkin, Sebastian Cotofana
BACKGROUND: Precise implantation of soft tissue fillers to treat the signs of aging is crucial for patient safety and the best aesthetic outcome. Injections are performed commonly with either needles or cannulas, but quantitative comparative data on precise implantation are still elusive. METHODS: Ten fresh-frozen cephalic foreheads (9 male, 1 female) were injected with radiopaque material using both needles and cannulas. Needle injection relied on a perpendicular transcutaneous approach, whereas cannulas were moved in the supra-periosteal plane until reaching the same location as the needle...
September 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28902161/biological-evaluation-of-flexible-polyurethane-poly-l-lactic-acid-composite-scaffold-as-a-potential-filler-for-bone-regeneration
#11
Yuk Fai Lui, Wing Yuk Ip
Degradable bone graft substitute for large-volume bone defects is a continuously developing field in orthopedics. With the advance in biomaterial in past decades, a wide range of new materials has been investigated for their potential in this application. When compared to common biopolymers within the field such as PLA or PCL, elastomers such as polyurethane offer some unique advantages in terms of flexibility. In cases of bone defect treatments, a flexible soft filler can help to establish an intimate contact with surrounding bones to provide a stable bone-material interface for cell proliferation and ingrowth of tissue...
September 13, 2017: Materials
https://www.readbyqxmd.com/read/28866223/development-of-polyurethanes-for-bone-repair
#12
REVIEW
M Marzec, J Kucińska-Lipka, I Kalaszczyńska, H Janik
The purpose of this paper is to review recent developments on polyurethanes aimed at the design, synthesis, modifications, and biological properties in the field of bone tissue engineering. Different polyurethane systems are presented and discussed in terms of biodegradation, biocompatibility and bioactivity. A comprehensive discussion is provided of the influence of hard to soft segments ratio, catalysts, stiffness and hydrophilicity of polyurethanes. Interaction with various cells, behavior in vivo and current strategies in enhancing bioactivity of polyurethanes are described...
November 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28865186/hyaluronic-acid-hydroxyapatite-nanocomposite-hydrogels-for-enhanced-biophysical-and-biological-performance-in-a-dermal-matrix
#13
Seol-Ha Jeong, Yingfang Fan, Kwang-Hee Cheon, Jaeuk Baek, Sukwha Kim, Hyoun-Ee Kim
A hyaluronic acid (HAc) - hydroxyapatite (HAp) nanocomposite (HAc-nanoHAp) hydrogel was fabricated through an in situ precipitation process for mechanical and biological enhancement as a soft tissue augmentation product. In this study, these composite hydrogel fillers were analyzed from three different perspectives and compared with pure HAc hydrogel for soft tissue augmentation application: 1) rheological behaviors, 2) in vivo lateral diffusion under mouse skin, and 3) wrinkle improvement in a photo-aged mouse model...
September 2, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28858938/pilot-study-examining-the-safety-and-efficacy-of-calcium-hydroxylapatite-filler-with-integral-lidocaine-over-a-12-month-period-to-correct-temporal-fossa-volume-loss
#14
Margit L W Juhász, Melissa K Levin, Ellen S Marmur
BACKGROUND: Age-related volume loss in the temporal fossae is due to thinning of the epidermis, loss of subcutaneous structural volume, and change in the bony architecture. Temporal concavities are important areas of 3-dimensional volume restoration. The temporal fossae is becoming an increasingly popular area for patients seeking soft tissue augmentation with injectable fillers such as calcium hydroxylapatite with integral lidocaine [CaHA (+)]. OBJECTIVE: This pilot study aims to define the safety, efficacy, technique, and patient-reported outcomes for injectable CaHA (+) to correct volume loss in the temporal fossae over a 12-month period...
August 29, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28858935/facial-soft-tissue-augmentation-in-males-an-anatomical-and-practical-approach
#15
Anthony M Rossi, Rebecca Fitzgerald, Shannon Humphrey
BACKGROUND: Soft tissue augmentation is increasingly being performed to treat male facial aging. OBJECTIVE: To review anatomical consideration specific for the male face and define an approach to male soft tissue augmentation that creates harmonious and natural results. CONCLUSION: Addressing aesthetic concerns in the upper face, midface, and lower face should be performed in concert with a combinatorial and pan facial approach. Correct filler placement at different areas of concern is important to achieve desired and natural results...
August 29, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28852297/assessment-of-the-efficacy-and-safety-of-hyaluronic-acid-gel-injection-in-the-restoration-of-fullness-of-the-upper-lips
#16
Taraneh Yazdanparast, Aniseh Samadi, Hournaz Hasanzadeh, Saman Ahmad Nasrollahi, Alireza Firooz, Mansour Nassiri Kashani
BACKGROUND AND AIM: Lips have a significant role in face aesthetic perception, and lip augmentation is one of the most commonly requested aesthetic procedures. Non-permanent dermal fillers, such as hyaluronic acid (HA), are used for augmenting the lips. This article presents the results of Phase II, before - after designed study, assessing the safety and efficacy of a soft tissue HA filler, for upper lip augmentation. MATERIALS AND METHODS: Investigators treated 10 healthy adult women 28-45 years old, using a single injection of Hyamax Kiss soft tissue HA filler (a product from Hyamed Laboratories, Switzerland) for upper lip augmentation...
April 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28841604/facial-assessment-and-injection-guide-for-botulinum-toxin-and-injectable-hyaluronic-acid-fillers-focus-on-the-lower-face
#17
Maurício de Maio, Woffles T L Wu, Greg J Goodman, Gary Monheit
This third article of a three-part series addresses techniques and recommendations for aesthetic treatment of the lower face. The lower face is considered an advanced area for facial aesthetic treatment. In this region, soft-tissue fillers play a more important role than neuromodulators and should be used first to provide structure and support before neuromodulators are considered for treatment of dynamic lines. Treatment of the lip, perioral region, and chin, in addition to maintaining balance of the lower face with the face overall, is challenging...
September 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28804933/chemical-functionalization-of-polysaccharides-towards-biocompatible-hydrogels-for-biomedical-applications
#18
Andreas Kirschning, Gerald Dräger, Nick Dibbert
Hydrogels have emerged as a highly interdisciplinary topic as they play a significant role for a vast number of applications. They have been studied extensively as materials for contact lenses, wound dressing and as filler material in soft-tissue augmentation, in which classical polymer backbones such as hydroxyethylmethacrylate (HEMA) are typically employed. More recently, polysaccharides have received attention, particularly in the fields of regenerative medicine and tissue engineering, as ideal candidate materials for artificial extracellular matrices (ECM)...
August 13, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28778112/-soft-tissue-fillers-state-of-the-art-and-future-perspectives
#19
Matthias M Aitzetmüller, Inesa Sukhova, Georg M Huemer, Hans-Guenther Machens, Jan-Thorsten Schantz, Dominik Duscher
In addition to cosmetic use, filler materials are frequently employed for reconstruction of contour defects. Scars and tissue defects after accidents, surgery and irradiation are also ideal indications for injectables. The ideal filler should be easy to inject, easy to form, and should remain in the body as long as possible. It should neither be allergenic or carcinogenic nor susceptible to infections or biofilms, but still potentially reversible, temperature-stable, and cheap. There is still no augmentation material that fulfils all of these criteria...
August 4, 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28746209/pedicled-buccal-fat-pad-for-the-augmentation-of-facial-depression-deformity-a-case-report
#20
Seiji Komatsu, Kou Ikemura, Yoshihiro Kimata
RATIONALE: Tissue augmentation of facial depression deformities can be achieved by volume replacement with autologous fat injection, dermal filler injection, etc. Here, we report a case of tissue augmentation of a facial depression deformity using a pedicled buccal fat pad (BFP). PATIENT CONCERNS: A 64-year-old woman was referred with a chief complaint of facial depression deformity. DIAGNOSES: Her molars had been removed at another hospital 12 years prior to this referral, and the patient suffered from a left cheek depression deformity as a sequela of a postextraction infection...
July 2017: Medicine (Baltimore)
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