keyword
MENU ▼
Read by QxMD icon Read
search

Risperidone

keyword
https://www.readbyqxmd.com/read/29048191/risperidone-in-combination-with-other-drugs-experimental-research-in-individuals-with-autism-spectrum-disorder
#1
Anita Li, Brian MacNeill, Hugo Curiel, Alan Poling
Many individuals with autism spectrum disorder simultaneously receive 2 or more drugs intended to improve their behavior, but few studies have evaluated the effects of such polypharmacy. This article summarizes those studies that have systematically examined the effects of risperidone, an antipsychotic drug that is approved by the U.S. Food and Drug Administration to treat "irritability" in children and adolescents with autism spectrum disorder, in combination with another drug with respect to experimental design, assessment techniques, drug co-administered, reported effects, and participant characteristics...
October 2017: Experimental and Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29045769/placebo-effects-in-the-treatment-of-noncognitive-symptoms-of-alzheimer-s-disease-analysis-of-the-catie-ad-data
#2
Chisa Ozawa, Rachel Roberts, Kazunari Yoshida, Takefumi Suzuki, Barry Lebowitz, Suzanne Reeves, Robert Howard, Takayuki Abe, Masaru Mimura, Hiroyuki Uchida
OBJECTIVE: To compare symptom trajectories between placebo and active drug responders and to examine whether early placebo improvement would be associated with subsequent placebo response in the treatment of patients with behavioral and psychological symptoms of dementia. METHODS: A post hoc analysis of data from 371 patients with DSM-IV Alzheimer's disease in Phase 1 of the Clinical Antipsychotic Trials of Intervention Effectiveness for Alzheimer's disease (CATIE-AD) (April 2001 to November 2004) was conducted...
October 17, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29045304/effect-of-clozapine-vs-other-second-generation-antipsychotics-on-hospitalization-and-seclusion-a-retrospective-mirror-image-study-in-a-japanese-public-psychiatric-hospital
#3
Fuminari Misawa, Takefumi Suzuki, Yasuo Fujii
BACKGROUND: Clozapine has been regarded as the gold standard for patients with treatment-resistant schizophrenia, but a recent network meta-analysis has questioned its relative superiority over other second-generation antipsychotics (SGAs) such as olanzapine and risperidone. PURPOSE: We conducted a retrospective mirror-image study of clozapine vs other SGAs to evaluate real-world effectiveness of clozapine in terms of the duration of hospitalization and seclusion, both of which represent a critical outcome...
October 17, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29037878/risperidone-ameliorates-cognitive-deficits-promotes-hippocampal-proliferation-and-enhances-notch-signaling-in-a-murine-model-of-schizophrenia
#4
Fen Xue, Yun-Chun Chen, Cui-Hong Zhou, Ying Wang, Min Cai, Wen-Jun Yan, Rui Wu, Hua-Ning Wang, Zheng-Wu Peng
Antipsychotic agents have been reported to promote hippocampal neurogenesis and improve cognitive deficits; yet, the molecular mechanisms underlying these actions remain unclear. In the present study, we used a murine model of schizophrenia induced by 5-day intraperitoneal injection with the non-competitive N-methyl-d-aspartate receptor antagonist MK801 (0.3mg/kg/day) to assess cognitive behavioral deficits, changes in Notch signaling, and cellular proliferation in the hippocampus of adult male C57BL/6 mice after 2-week administration of risperidone (Rip, 0...
October 13, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/29034440/risperidone-induced-metabolic-dysfunction-is-attenuated-by-curcuma-longa-extract-administration-in-mice
#5
Florent Auger, Françoise Martin, Olivier Pétrault, Jennifer Samaillie, Thierry Hennebelle, Mohamed-Sami Trabelsi, François Bailleul, Bart Staels, Régis Bordet, Patrick Duriez
Antipsychotics, such as risperidone, increase food intake and induce alteration in glucose and lipid metabolism concomitantly with overweight and body fat increase, these biological abnormalities belong to the metabolic syndrome definition (high visceral adiposity, hypertriglyceridemia, hyperglycemia, low HDL-cholesterol and high blood pressure). Curcumin is a major component of traditional turmeric (Curcuma longa) which has been reported to improve lipid and glucose metabolism and to decrease weight in obese mice...
October 16, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/29027815/l-carnosine-as-an-adjunctive-therapy-to-risperidone-in-children-with-autistic-disorder-a-randomized-double-blind-placebo-controlled-trial
#6
Reihaneh Hajizadeh-Zaker, Alireza Ghajar, Bita Mesgarpour, Mohsen Afarideh, Mohammad-Reza Mohammadi, Shahin Akhondzadeh
OBJECTIVES: This study aimed at investigating the efficacy and tolerability of l-carnosine as an add-on to risperidone in the management of children with autism. METHODS: This was a 10-week, randomized, double-blind, placebo-controlled study. Seventy drug-free children aged 4-12 years old with a diagnosis of autism spectrum disorder (ASD), according to the Diagnostic and Statistical Manual of Mental Disorders, fifth edition. (DSM-5) who had an Aberrant Behavior Checklist-Community (ABC-C) scale irritability subscale score of ≥12, entered the study...
October 13, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28987309/risperidone-in-the-emergency-setting-is-associated-with-more-hypotension-in-elderly-patients
#7
Michael P Wilson, Kimberly Nordstrom, Austin Hopper, Austin Porter, Edward M Castillo, Gary M Vilke
BACKGROUND: Expert consensus panels have recommended risperidone as first-line treatment for agitation of psychiatric origin. However, there are few if any studies on this medication in the emergency setting. OBJECTIVES: To assess the hemodynamic effects of risperidone in an emergency department (ED) setting, stratified by age. METHODS: This is a structured chart review of all patients who received oral risperidone over a 6-year period in an ED setting, excluding patients who received this medication as a prescription refill...
October 5, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28982383/unexpected-hypotension-in-catecholamine-reversal-a-case-report
#8
Yohei Okada, Wataru Ishi, Hiromichi Narumiya, Ryoji Liduka
BACKGROUND: Catecholamine agents are commonly used to support circulation; however, they may cause unexpected hypotension in a special situation. Here we describe the first unexpected case of hypotension in response to catecholamine agents. CASE PRESENTATION: A 29-year-old Japanese man with schizophrenia was transferred to our emergency department. He was in shock and in coma. After fluid resuscitation, we induced catecholamine agents; however, his blood pressure decreased to 59/40 mmHg in response to catecholamine infusion...
October 6, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28966250/psychiatric-patients-with-antipsychotic-drug-induced-hyperprolactinemia-and-menstruation-disorders
#9
Kenshi Takechi, Yurika Yoshioka, Hitoshi Kawazoe, Mamoru Tanaka, Shingo Takatori, Miwako Kobayashi, Ichiro Matsuoka, Hiroaki Yanagawa, Yoshito Zamami, Masaki Imanishi, Keisuke Ishizawa, Akihiro Tanaka, Hiroaki Araki
Treatment with antipsychotic drugs has been associated with hyperprolactinemia. The same antipsychotic drugs have also been associated with side effects such as menstruation disorders. The aim of this study was to evaluate the prevalence of hyperprolactinemia and menstruation disorders in women undergoing antipsychotic treatment. We performed a retrospective chart review study of psychiatric patients who underwent laboratory testing for serum prolactin (PRL) level between March 2011 and March 2015 in Ehime University Hospital...
2017: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28962597/periodic-catatonia-with-long-term-treatment-a-case-report
#10
Ruei-An Chen, Tiao-Lai Huang
BACKGROUND: Periodic catatonia has long been a challenging diagnosis and there are no absolute guidelines for treatment when precipitating factors are also unclear. We report a schizophrenia patient with periodic catatonia with a 15-year treatment course. A possible correlation between decreased daylight exposure and periodic attacks has been observed. CASE PRESENTATION: We describe a 49-year-old woman with periodic catatonia associated with schizophrenia with 15 years of follow-up...
September 29, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28956466/preparation-and-characterization-of-silk-fibroin-hydrogel-as-injectable-implants-for-sustained-release-of-risperidone
#11
Atefeh Ebrahimi, Komail Sadrjavadi, Marziyeh Hajialyani, Yalda Shokoohinia, Ali Fattahi
The principal objective of the present study is to achieve a depot formulation of Risperidone by gelation of silk fibroin (SF). For this purpose, hydrochloric acid (HCl)/acetone based and methanol based hydrogels were prepared with different drug/polymer ratios (1:3, 1:6 and 1:15). For all the drug-loaded methanol based hydrogels, gel transition of SF solutions occurred immediately and gelation time was 1 min, while the gelation time of HCL/acetone based hydrogels was around 360 min. From Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD) spectra, solvent systems, and Risperidone could induce β-sheet structure, but HCL/acetone system had the lowest effect on induction of β-sheets...
September 28, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28955666/comparison-of-the-effect-of-lithium-plus-quetiapine-with-lithium-plus-risperidone-in-children-and-adolescents-with-bipolar-i-disorder-a-randomized-clinical-trial
#12
Nastaran Habibi, Nasrin Dodangi, Ali Nazeri
Background: In the treatment of bipolar disorder in youths, often more than one medication should be prescribed. In the current study, we compared the efficacy and tolerability of the combination of lithium and quetiapine with lithium and risperidone in the treatment of manic or mixed episodes in children and adolescents. Methods: Thirty patients (aged 10-18 years) who were hospitalized for a manic or mixed episode were recruited from consecutive inpatient admissions to the Child and Adolescent Psychiatric Unit at Razi Psychiatric Hospital (University of Social Welfare and Rehabilitation Sciences, Tehran, Iran) from June 2012 to September...
2017: Medical Journal of the Islamic Republic of Iran
https://www.readbyqxmd.com/read/28954970/effectiveness-of-levodopa-treatment-for-diabetic-chorea-with-reduced-striatal-accumulation-in-dopamine-transporter-spect-a-case-report
#13
Katsunori Yokoi, Tomoyuki Kazuta, Ryouta Torii, Toshihiro Endo, Amane Araki, Shinichi Terao
We report the case of a 77-year-old woman with diabetic chorea, which presented as hemiballism of the right limbs. Initial blood examination revealed that sugar and hemoglobin A1c levels were 732 mg/dl and 12.2%, respectively. Thus, a diagnosis of hyperglycemic hyperosmolar syndrome was made at a previous hospital. Ballism of the right limbs developed after 10 days and progressively worsened. After a month, the patient was admitted to our hospital. Brain MRI (axial T1-weighted imaging) revealed a high-signal-intensity area in the left striatum...
September 28, 2017: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/28953846/does-risperidone-long-acting-injectable-depot-rlai-reduce-number-of-admissions-to-hospital
#14
Hellme Najim, Ashish Pathak, Andrea Pathak
BACKGROUND: Adherence to treatment is a major issue in relapse prevention in schizophrenia. Injectable depot has been claimed to improve non-adherence. A study in the North of England has shown that risperidone long acting injectable form has reduced number of admissions and number of days stayed in hospital. Our study aimed to replicate the previous study in the South of England. METHODS: A retrospective study was conducted in the South Essex Foundation University NHS trust...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28953820/study-on-the-prescribing-patterns-of-antipsychotic-medication-in-a-rural-england-community-mental-health-team
#15
Madhavan Seshadri, Ahmed Elsemary, Madhusudan Deepak Thalitaya, Lawrence Chikodzore, Priya Nagalingam
INTRODUCTION: Providing comprehensive services for about 400 patients in the South Herefordshire area, the community mental health team manages cases of varying severity and complexity, ranging from Schizophrenia, to neuroses and disorders of adult personality. Antipsychotic medication remains a mainstay of treatment and management for patients under the team case load; hence a need exists for a detailed look into the prescription patterns of such medications. AIM: The aim of this study was to look into the prescribing patterns of antipsychotics for a sample of 50 patients in the South Herefordshire community team during the year of 2016 (from Jan 2016 to Dec 2016), as well as investigate whether these antipsychotics were licensed to be used for the corresponding diagnoses of these patients...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28953766/delusional-parasitosis-treated-by-atypical-antipsychotic-and-selective-serotonin-reuptake-inhibitor-a-case-report
#16
Tiffany Roulet, Nicolas Zdanowicz
BACKGROUND: Delusional parasitosis (DP) is an uncommon psychiatric disorder. Patients suffering from this disorder have the fixed false belief of being infested by a parasite. Because of this condition, patients mainly consult with dermatologists or general practitioners. They are often reluctant to see a psychiatrist and to take treatment with antipsychotics because of their belief. The following describes the case of a woman who has the particularity that the DP started a few days after sertraline interruption...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28948091/successful-treatment-with-risperidone-increases-5-ht-3a-receptor-gene-expression-in-patients-with-paranoid-schizophrenia-data-from-a-prospective-study
#17
Hongying Chen, Yong Fan, Lei Zhao, Yong Hao, Xiajun Zhou, Yangtai Guan, Zezhi Li
INTRODUCTION: The relationship between peripheral 5-HT3A receptor mRNA level and risperidone efficiency in paranoid schizophrenia patients is still unknown. METHODS: A total 52 first-episode and drug-naive paranoid schizophrenia patients who were treated with risperidone and 53 matched healthy controls were enrolled. Patients were naturalistically followed up for 8 weeks. Positive and Negative Syndrome Scale (PANSS) was applied to assess symptom severity of the patients at baseline and at the end of 8th week...
September 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28945664/correlates-of-nonimprovement-to-pharmacotherapy-for-chronic-antidepressant-resistant-military-service-related-posttraumatic-stress-disorder-insights-from-the-veterans-affairs-cooperative-study-no-504
#18
Simon P Byrne, John H Krystal, Robert A Rosenheck, Jennier Vessicchio, Robert H Pietrzak
BACKGROUND: Posttraumatic stress disorder (PTSD) is a chronic and often difficult-to-treat condition that is prevalent among military veterans. First-line pharmacotherapy for this population typically involves antidepressants; however, veterans who do not improve are sometimes prescribed antipsychotics such as risperidone. A 2011 randomized controlled trial of adjunctive risperidone versus placebo for veterans with chronic, antidepressant-resistant, military service-related PTSD revealed no difference between groups...
September 22, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28942217/risperidone-versus-olanzapine-among-patients-with-schizophrenia-participating-in-supported-employment-eighteen-month-outcomes
#19
Douglas L Noordsy, Shirley M Glynn, Catherine A Sugar, Christopher D O'Keefe, Stephen R Marder
This study compares the efficacy and tolerability of olanzapine versus risperidone among patients with schizophrenia who are established in outpatient psychiatric care and entering supported employment. A multicenter, randomized, double-blind trial was conducted among 107 outpatients with schizophrenia, who were cross-titrated to flexible dose risperidone or olanzapine over 2 weeks. Clinical endpoints included time to hospitalization and persistence on assigned medication. Weight, laboratory tests, psychopathology, neurologic side effects, social adjustment and role functioning were assessed at 3-6 month intervals...
September 8, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28940543/association-between-5-htr2c-759c-t-rs3813929-and-697g-c-rs518147-gene-polymorphisms-and-risperidone-induced-insulin-resistance-syndrome-in-an-indian-population
#20
Saibal Das, Jayanta Kumar Dey, Niranjan Prabhu Ss, Sachin David, Aniket Kumar, Deepa Braganza, Margaret Shanthi Fx
This study was performed to examine the association of 2 functional polymorphisms of the promoter region of the serotonin 5-HTR2C receptor gene: -759C/T (rs3813929) and -97G/C (rs518147) with risperidone-induced insulin resistance syndrome in an Indian population. In this case-control study, 52 adult patients of either sex, having no insulin resistance syndrome before initiating treatment, who were previously drug naive and who received risperidone monotherapy for ≥1 year, were recruited in 2 arms. Of them, 26 had risperidone-induced insulin resistance syndrome, and 26 did not have risperidone-induced insulin resistance syndrome...
September 22, 2017: Journal of Clinical Pharmacology
keyword
keyword
4837
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"