Ian R Reid, Richard Eastell, Ignac Fogelman, Jonathon D Adachi, Amy Rosen, Coen Netelenbos, Nelson B Watts, Ego Seeman, Angelina V Ciaccia, Michael W Draper
BACKGROUND: Although many studies have assessed the effects of estrogen and raloxifene hydrochloride on bone mineral density and serum lipid concentrations, there are few direct comparative data. METHODS: Randomized placebo-controlled trial for 3 years, intention-to-treat analysis. Six hundred nineteen postmenopausal women with prior hysterectomy (mean age, 53.0 years) were studied in 38 centers in Europe, North America, Australasia, and South Africa. They were randomized to 60 mg/d or 150 mg/d of raloxifene, 0...
April 26, 2004: Archives of Internal Medicine