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https://www.readbyqxmd.com/read/29135072/measuring-human-placental-blood-flow-with-multidelay-3d-grase-pseudocontinuous-arterial-spin-labeling-at-3t
#1
Xingfeng Shao, Dapeng Liu, Thomas Martin, Teresa Chanlaw, Sherin U Devaskar, Carla Janzen, Aisling M Murphy, Daniel Margolis, Kyunghyun Sung, Danny J J Wang
BACKGROUND: Placenta influences the health of both a woman and her fetus during pregnancy. Maternal blood supply to placenta can be measured noninvasively using arterial spin labeling (ASL). PURPOSE: To present a multidelay pseudocontinuous arterial spin labeling (pCASL) combined with a fast 3D inner-volume gradient- and spin-echo (GRASE) imaging technique to simultaneously measure placental blood flow (PBF) and arterial transit time (ATT), and to study PBF and ATT evolution with gestational age during the second trimester...
November 14, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29108612/sleep-disordered-breathing-caused-by-chronic-opioid-use-diverse-manifestations-and-their-management
#2
REVIEW
Susmita Chowdhuri, Shahrokh Javaheri
Opioid-induced sleep disordered breathing presents a therapeutic predicament with the increasing incidence of prescription opioid use for noncancer chronic pain in the United States. Central sleep apnea with a Biot or cluster breathing pattern is characteristic of polysomnography studies; however, long-term clinical outcomes and the impact of therapy remain unknown. Novel ampakine-based therapies are being investigated. Randomized controlled trials with therapies that target the underlying pathophysiologic mechanisms of opioid-induced sleep disordered breathing are required...
December 2017: Sleep Medicine Clinics
https://www.readbyqxmd.com/read/29075622/autistic-siblings-with-novel-mutations-in-two-different-genes-insight-for-genetic-workups-of-autistic-siblings-and-connection-to-mitochondrial-dysfunction
#3
Barrett J Burger, Shannon Rose, Sirish C Bennuri, Pritmohinder S Gill, Marie L Tippett, Leanna Delhey, Stepan Melnyk, Richard E Frye
The prevalence of autism spectrum disorder (ASD) is high, yet the etiology of this disorder is still uncertain. Advancements in genetic analysis have provided the ability to identify potential genetic changes that may contribute to ASD. Interestingly, several genetic syndromes have been linked to metabolic dysfunction, suggesting an avenue for treatment. In this case study, we report siblings with ASD who had similar initial phenotypic presentations. Whole exome sequencing (WES) revealed a novel c.795delT mutation in the WDR45 gene affecting the girl, which was consistent with her eventual progression to a Rett-like syndrome phenotype including seizures along with a stereotypical cyclic breathing pattern...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29064170/sleep-disordered-breathing-in-bronchopulmonary-dysplasia
#4
Luis E Ortiz, Sharon A McGrath-Morrow, Laura M Sterni, Joseph M Collaco
BACKGROUND: There are limited data on the effect of bronchopulmonary dysplasia (BPD) on sleep disordered breathing (SDB). We hypothesized that both the severity of prematurity and BPD would increase the likelihood of SDB in early childhood. Our secondary aim was to evaluate the association of demographic factors on the development of SDB. METHODS: This is a retrospective study of patient factors and overnight polysomnogram (PSG) data of children enrolled in our BPD registry between 2008 and 2015...
October 24, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29060172/monitoring-of-nocturnal-central-sleep-apnea-in-heart-failure-patients-using-noncontact-respiratory-differences
#5
Rami N Khushaba, Jeff Armitstead, Klaus Schindhelm
Monitoring of respiration patterns allows the early detection of various breathing disorders and may better identify those at risk for adverse acute outcomes in a variety of clinical settings. In this paper, we report on the use of SleepMinder (SM), a bedside non-contact Doppler-based biomotion recording sensor, to monitor remotely the nocturnal respiration patterns of 50 patients with systolic Heart failure (HF) while undergoing a lab based Polysomnography (PSG) test. A new respiration rate (RR) monitoring algorithm was developed based on the collected overnight radar signals...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29059625/association-of-pm2-5-with-sleep-disordered-breathing-from-a-population-based-study-in-northern-taiwan-urban-areas
#6
Yen-Ling Shen, Wen-Te Liu, Kang-Yun Lee, Hsiao-Chi Chuang, Hua-Wei Chen, Kai-Jen Chuang
Recent studies suggest that exposure to air pollution might be associated with severity of sleep-disordered breathing (SDB). However, the association between air pollution exposure, especially particulate matter with aerodynamic diameters <= 2.5 μm (PM2.5), and SDB is still unclear. We collected 4312 participants' data from the Taipei Medical University Hospital's Sleep Center and air pollution data from the Taiwan Environmental Protection Administration. Associations of particulate matter with aerodynamic diameters <=10 μm (PM10), PM2...
October 20, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29031758/the-association-of-mothers-and-fathers-insomnia-symptoms-with-school-aged-children-s-sleep-assessed-by-parent-report-and-in-home-sleep-electroencephalography
#7
Natalie Urfer-Maurer, Rebekka Weidmann, Serge Brand, Edith Holsboer-Trachsler, Alexander Grob, Peter Weber, Sakari Lemola
OBJECTIVE: Sleep plays an essential role for children's well-being. Because children's sleep is associated with parental sleep patterns, it must be considered in the family context. As a first aim of the present study, we test whether parental insomnia symptoms are related to children's in-home sleep-electroencephalography (EEG). Second, we examine the association between parental insomnia symptoms and maternal and paternal perception of children's sleep using actor-partner interdependence models...
October 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29023738/klf2-mediates-enhanced-chemoreflex-sensitivity-disordered-breathing-and-autonomic-dysregulation-in-heart-failure
#8
Noah J Marcus, Rodrigo Del Rio, Yanfeng Ding, Harold D Schultz
KEY POINTS: Enhanced carotid body chemoreflex activity contributes to development of disordered breathing patterns, autonomic dysregulation and increases in incidence of arrhythmia in animal models of reduced ejection fraction heart failure. Chronic reductions in carotid artery blood flow are associated with increased carotid body chemoreceptor activity. Krüppel-like Factor 2 (KLF2) is a shear stress-sensitive transcription factor that regulates the expression of enzymes which have previously been shown to play a role in increased chemoreflex sensitivity...
September 6, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28970105/sleep-patterns-and-hypertension-using-actigraphy-in-the-hispanic-community-health-study-study-of-latinos
#9
Alberto R Ramos, Jia Weng, Douglas M Wallace, Megan R Petrov, William K Wohlgemuth, Daniela Sotres-Alvarez, Jose S Loredo, Kathryn J Reid, Phyllis C Zee, Yasmin Mossavar-Rahmani, Sanjay R Patel
BACKGROUND: The aim of this study was to evaluate the association between actigraphy-based measures of sleep and prevalent hypertension in a sample of US Latinos. METHODS: We analyzed data from 2,148 participants of the Sueño Sleep Ancillary Study of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), who underwent 1 week of wrist actigraphy to characterize sleep duration, sleep efficiency, sleep fragmentation index, and daytime naps. Insomnia was defined as an Insomnia Severity Index ≥ 15...
September 29, 2017: Chest
https://www.readbyqxmd.com/read/28964100/spatial-acoustic-radiation-of-respiratory-sounds-for-sleep-evaluation
#10
Noam R Shabtai, Yaniv Zigel
Body posture has an effect on sleeping quality and breathing disorders and therefore it is important to be recognized for the completion of the sleep evaluation process. Since humans have a directional acoustic radiation pattern, it is hypothesized that microphone arrays can be used to recognize different body postures, which is highly practical for sleep evaluation applications that already measure respiratory sounds using distant microphones. Furthermore, body posture may have an effect on distant microphone measurement; hence, the measurement can be compensated if the body posture is correctly recognized...
September 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28953832/biofeedback-and-neurofeedback-application-in-the-treatment-of-migraine
#11
Sanja Martic-Biocina, Ivana Zivoder, Goran Kozina
INTRODUCTION: Biofeedback is a non-invasive method of measurement of physiological functions. Precise instruments measure the slightest changes of different body functions-which are then in a clear and understandable manner shown in the form of feedback. Person gets an insight into what is going on inside the body and thus learns to change the patterns of behavior to improve health and performance. Any changes that are wanted are rewarded, which leads to learning of the new patterns of behavior...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28947266/dynamics-of-defensive-response-mobilization-during-repeated-terminations-of-exposure-to-increasing-interoceptive-threat
#12
Christoph Benke, Elischa Krause, Alfons O Hamm, Christiane A Pané-Farré
Resistant avoidance behaviors play a crucial role in the maintenance of anxiety disorders and are therefore central targets of therapeutic interventions. In the present study, the development of avoidance behavior was investigated in 24 healthy participants who repeatedly prematurely terminated the exposure to increasing interoceptive threat, i.e., the feeling of dyspnea induced by increasing inspiratory resistive loads that were followed by the ultimate threat, a short breathing occlusion. Physiological responses and subjective anxiety preceding terminations were compared to matched intervals of a matched control group (N=24) who completed the exposure...
September 23, 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/28945103/insurance-coverage-and-acute-care-revisits-after-pediatric-ambulatory-tonsillectomy
#13
Dmitry Tumin, Vidya T Raman, Joseph D Tobias
We investigated whether patterns of health insurance coverage were associated with 30-day all-cause acute care revisits after ambulatory tonsillectomy at a free-standing quaternary-care pediatric hospital. Insurance patterns were classified from past encounters as continuous private, continuous Medicaid, Medicaid-to-private change, or private-to-Medicaid change. Among 478/675 boys/girls (age 9 ± 4 years) selected for analysis, 148 (13%) had 30-day revisits, whereas 96 (8%) changed from Medicaid to private insurance, and 99 (9%) changed from private insurance to Medicaid...
September 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28918418/new-aspects-in-the-pathomechanism-of-diseases-of-civilization-particularly-psychosomatic-disorders-part-1-theoretical-background-of-a-hypothesis
#14
Andras Sikter, Zoltan Rihmer, Roberto de Guevara
The stress defence-cascade is mostly not biphasic as Cannon thought, the sympathicotonic stress response is preceded by a vagotonic phase called freeze response. Alteration of the carbon dioxide level plays an important role during defence-cascade as its changes interfere with stress hormones, e.g. with catecholamines, thus affecting the degree of arousal. In case of humans, learned behaviour dominates instead of instinctive, so the fight-or-flight often lags; the consequence can be persistent hypocapnia or hypercapnia...
June 2017: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/28905471/novel-assessment-tool-to-detect-breathing-pattern-disorder-in-patients-with-refractory-asthma
#15
Sarah Todd, Emil S Walsted, Lizzie Grillo, Rebecca Livingston, Andrew Menzies-Gow, James H Hull
BACKGROUND AND OBJECTIVE: Breathing pattern disorder (BPD) can co-exist with and mimic asthma, acting to amplify symptoms and confound assessment of disease control, resulting in inappropriate treatment escalation. The aim of this research was to report the utility of a novel breathing pattern assessment tool (BPAT) to detect BPD in treatment-refractory asthma. METHODS: As a component of a multidisciplinary assessment, adult patients referred with treatment-refractory asthma underwent respiratory physiotherapy assessment to diagnose BPD...
September 14, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28893762/sleep-disordered-breathing-in-acute-ischemic-stroke-a-mechanistic-link-to-peripheral-endothelial-dysfunction
#16
Nadja Scherbakov, Anja Sandek, Nicole Ebner, Miroslava Valentova, Alexander Heinrich Nave, Ewa A Jankowska, Jörg C Schefold, Stephan von Haehling, Stefan D Anker, Ingo Fietze, Jochen B Fiebach, Karl Georg Haeusler, Wolfram Doehner
BACKGROUND: Sleep-disordered breathing (SDB) after acute ischemic stroke is frequent and may be linked to stroke-induced autonomic imbalance. In the present study, the interaction between SDB and peripheral endothelial dysfunction (ED) was investigated in patients with acute ischemic stroke and at 1-year follow-up. METHODS AND RESULTS: SDB was assessed by transthoracic impedance records in 101 patients with acute ischemic stroke (mean age, 69 years; 61% men; median National Institutes of Health Stroke Scale, 4) while being on the stroke unit...
September 11, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28883930/breathing-swallowing-discoordination-is-associated-with-frequent-exacerbations-of-copd
#17
Shinsuke Nagami, Yoshitaka Oku, Naomi Yagi, Susumu Sato, Ryuji Uozumi, Satoshi Morita, Yoshie Yamagata, Jun Kayashita, Kazuya Tanimura, Atsuyasu Sato, Ryosuke Takahashi, Shigeo Muro
INTRODUCTION: Impaired coordination between breathing and swallowing (breathing-swallowing discoordination) may be a significant risk factor for the exacerbation of chronic obstructive pulmonary disease (COPD). We examined breathing-swallowing discoordination in patients with COPD using a non-invasive and quantitative technique and determined its association with COPD exacerbation. METHODS: We recruited 65 stable outpatients with COPD who were enrolled in our prospective observational cohort study and did not manifest an apparent swallowing disorder...
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/28852230/sleep-pattern-and-sleep-hygiene-practices-among-nigerian-schooling-adolescents
#18
Igoche David Peter, Halima Adamu, Mustafa O Asani, Ibrahim Aliyu, Umar A Sabo, Umar I Umar
BACKGROUND: Sleep problems, especially in the adolescent stage of development, may be associated with excessive daytime sleepiness, impaired neurocognitive function, and a host of others leading to suboptimal performance. OBJECTIVES: To determine the pattern of sleep problems in school-going adolescents based on the bedtime problems; excessive daytime sleepiness; awakenings during the night and problems falling back asleep; regularity and duration of sleep; sleep-disordered breathing (BEARS) sleep screening algorithm...
July 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28843731/ethanol-induced-autonomic-responses-and-risk-taking-increase-in-young-adults-with-a-positive-family-history-of-alcohol-problems
#19
Florencia Caneto, Ricardo Marcos Pautassi, Angelina Pilatti
The mechanisms that underlie the greater prevalence of alcohol use disorders in individuals with a positive family history (FH+) of alcohol abuse are still under investigation. These subjects may exhibit differential sensitivity to alcohol's effects on psychomotor stimulation and impulsivity. Alcohol-induced psychomotor stimulation, measured as the heart rate (HR) response, is a proxy for the positive rewarding effects of the drug. We analyzed alcohol-induced effects on time perception (Time Production Task), risk taking (Balloon Analogue Risk Task [BART]), and HR in FH+ and FH- participants...
August 16, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28838793/the-impact-of-glottal-configuration-on-speech-breathing
#20
Elizabeth S Heller Murray, Carolyn M Michener, Laura Enflo, Gabriel J Cler, Cara E Stepp
OBJECTIVE: The purpose of this study was to examine whether changes in respiratory patterns occurred in response to volitional changes in glottal configuration. METHODS: Twelve vocally healthy participants read a passage while wearing the Inductotrace respiratory inductive plethysmograph, which measures the excursions of the rib cage and abdomen. Participants read the passage 5 times in a typical speaking voice (baseline phase), 10 times in an experimental voice, which was similar to a breathy vocal quality (experimental phase), and 5 times again in a typical speaking voice (return phase)...
August 21, 2017: Journal of Voice: Official Journal of the Voice Foundation
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