Erik Cederlöf, Minna Holm, Heidi Taipale, Jari Tiihonen, Antti Tanskanen, Markku Lähteenvuo, Kaisla Lahdensuo, Olli Kampman, Asko Wegelius, Erkki Isometsä, Tuula Kieseppä, Aarno Palotie, Jaana Suvisaari, Tiina Paunio
BACKGROUND: Sleep problems are common and related to a worse quality of life in patients with schizophrenia. Almost all patients with schizophrenia use antipsychotic medications, which usually increase sleep. Still, the differences in subjective sleep outcomes between different antipsychotic medications are not entirely clear. METHODS: This study assessed 5466 patients with schizophrenia and is part of the nationwide Finnish SUPER study. We examined how the five most common antipsychotic medications (clozapine, olanzapine, quetiapine, aripiprazole, and risperidone) associate with questionnaire-based sleep problems in logistic regression analyses, including head-to-head analyses between different antipsychotic medications...
April 4, 2024: Schizophrenia Research