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https://www.readbyqxmd.com/read/29905593/delivery-of-tdf-ftc-for-pre-exposure-prophylaxis-to-prevent-hiv-1-acquisition-in-young-adult-men-who-have-sex-with-men-and-transgender-women-of-color-using-a-urine-adherence-assay
#1
Linden Lalley-Chareczko, Devon Clark, S Caitlin Conyngham, Athena Zuppa, Ganesh Moorthy, Karam Mounzer, Helen Koenig
BACKGROUND: Pre-exposure prophylaxis(PrEP) for HIV prevention with daily TDF/FTC is effective when taken consistently. Currently, there is no objective way to monitor PrEP adherence. Urine has been shown to be highly correlated with plasma tenofovir levels, with urine tenofovir levels >1000ng/mL demonstrating recent(1-2 days) adherence to PrEP. SETTING: The present study was conducted at an urban community health center in Philadelphia, Pennsylvania. METHODS: PrEP was administered to 50 young men who have sex with men and transgender women of color using weekly, biweekly, and/or monthly dispensation schedules...
June 12, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29762169/change-in-sexual-risk-behaviour-after-six-months-of-pre-exposure-prophylaxis-use-results-from-the-amsterdam-prep-demonstration-project
#2
Elske Hoornenborg, Liza Coyer, Anna van Laarhoven, Roel Achterbergh, Henry de Vries, Maria Prins, Maarten Schim van der Loeff
OBJECTIVE: HIV pre-exposure prophylaxis (PrEP) use may lead to higher STI incidence via behavioral risk compensation. We examined changes in sexual behaviour between baseline and six months after PrEP initiation among men who have sex with men (MSM) and transgender women (TGW). DESIGN: Prospective, open-label demonstration study at a large sexually transmitted infections (STI) clinic in Amsterdam, the Netherlands. METHODS: Participants answered questions about sexual behaviour in the preceding three months, including number of anal sex partners and frequency of anal sex with and without condom by partner type and were tested for STI...
May 11, 2018: AIDS
https://www.readbyqxmd.com/read/29716789/comparison-of-hiv-status-between-transgender-women-and-men-who-have-sex-with-men-a-meta-analysis
#3
Tian-Zhang Song, Ming-Xu Zhang, Han-Dan Zhang, Yu Xiao, Wei Pang, Yong-Tang Zheng
As key population groups in HIV infection, transgender women (TGW) share the same oral and anal sexual practices with men who have sex with men (MSM). However, the differences in HIV rates between the two groups are still unclear. In our study, relevant publications were electronically searched in three databases. After excluding irrelevant studies based on review of the title, abstract, and full text, a total of 24 studies, including 37,521 cases, were identified. There were no significant differences between TGW and MSM regarding HIV status and condom use...
April 11, 2018: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/29712625/intervention-to-increase-hiv-testing-among-substance-using-young-men-who-have-sex-with-men-protocol-for-a-randomized-controlled-trial
#4
Rob Stephenson, Erin E Bonar, Adam Carrico, Alexis Hunter, Daniel Connochie, Rebecca Himmelstein, Jose Bauermeister
BACKGROUND: Young men who have sex with men (YMSM) and transgender people in the Detroit Metro Area are the only risk group for whom the incidence of HIV and sexually transmitted infections (STI) has increased since 2000, with HIV incidence nearly doubling among youth. Substance use (including alcohol), which is relatively frequent among YMSM and transgender people, creates barriers to the optimal delivery of HIV prevention and care services. Standard HIV counseling, testing, and referral (CTR) is limited in providing strategies to identify and address substance use...
April 30, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29688317/hiv-and-viral-hepatitis-among-imprisoned-key-populations
#5
Andrea L Wirtz, Ping T Yeh, Natalie L Flath, Chris Beyrer, Kate Dolan
Prisons and other closed facilities create opportunities for transmission of human immunodeficiency virus (HIV) and viral hepatitis during detention and after release. We conducted a systematic review and meta-analysis of peer-reviewed publications (2005-2015) to describe the prevalence of HIV, hepatitis C virus, and hepatitis B virus among key populations in prisons worldwide and to compare estimates of infection with those of other prison populations. Most data were reported for people who inject drugs (PWID; n = 72) and for men who have sex with men (MSM; n = 21); few data were reported on sex workers (SW; n = 6), or transgender women (n = 2)...
June 1, 2018: Epidemiologic Reviews
https://www.readbyqxmd.com/read/29672234/transgender-college-students-academic-resilience-and-striving-to-cope-in-the-face-of-marginalized-health
#6
Jenna B Messman, Leigh A Leslie
OBJECTIVE: To examine health behavior and outcome disparities between transgender, female, and male participants in a national sample of US college students. Participants and Method Summary: Analyses utilized secondary data from 32,964 undergraduate and graduate students responding to the Fall 2013 American College Health Association-National College Health Assessment; 65.8% were female, 0.4% were transgender, 67.9% were white, and 90.4% were heterosexual. RESULTS: Transgender students reported more mental health diagnoses, trauma, and suicidality; experienced more violence and less safety, reported more sex partners and sexually transmitted infections (STIs); higher rates of illicit and non-prescription substance use and binge drinking use while engaging in less harm reduction behavior; and reported more barriers to academic success...
April 19, 2018: Journal of American College Health: J of ACH
https://www.readbyqxmd.com/read/29655906/substance-use-and-sex-index-susi-first-stage-development-of-an-assessment-tool-to-measure-behaviour-change-in-sexualised-drug-use-for-substance-use-treatment-studies
#7
Nadine Ezard, Beatrice Webb, Brendan Clifford, Michael E Cecilio, Amanda Jellie, Toby Lea, Craig Rodgers, Simon Ruth, Raimondo Bruno
BACKGROUND: Existing tools for measuring blood-borne virus (BBV) and sexually transmitted infection (STI) transmission risk behaviours in substance use interventions have limited capacity to assess risk behaviours across varied social, cultural and epidemiological contexts; have not evolved alongside HIV treatment and prevention innovations; or accounted for sexual contexts of drug use including among a range of lesbian, gay, bisexual, transgender, intersex and queer (LGBTIQ) sub-communities...
May 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29603900/men-who-have-sex-with-men-more-often-chose-daily-than-event-driven-use-of-pre-exposure-prophylaxis-baseline-analysis-of-a-demonstration-study-in-amsterdam
#8
Elske Hoornenborg, Roel Ca Achterbergh, Maarten F Schim van der Loeff, Udi Davidovich, Jannie J van der Helm, Arjan Hogewoning, Yvonne Thp van Duijnhoven, Gerard Jb Sonder, Henry Jc de Vries, Maria Prins
INTRODUCTION: The Amsterdam PrEP project is a prospective, open-label demonstration study at a large sexually transmitted infection (STI) clinic. We examined the uptake of PrEP; the baseline characteristics of men who have sex with men (MSM) and transgender persons initiating PrEP; their choices of daily versus event-driven PrEP and the determinants of these choices. METHODS: From August 2015 through May 2016, enrolment took place at the STI clinic of the Public Health Service of Amsterdam, the Netherlands...
March 2018: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29554240/epidemiology-of-hiv-sexually-transmitted-infections-viral-hepatitis-and-tuberculosis-among-incarcerated-transgender-people-a-case-of-limited-data
#9
Tonia C Poteat, Mannat Malik, Chris Beyrer
Transgender people experience a disproportionate burden of human immunodeficiency virus (HIV) and incarceration. Discrimination, victimization, poverty, and poor mental health drive vulnerability to HIV and related infections, as well as risk of arrest, detention, and incarceration. In this paper, we systematically review published data on HIV, sexually transmitted infections, viral hepatitis, and tuberculosis among incarcerated transgender people; describe potential structural determinants of HIV risk and transmission; identify gaps in the literature; and make recommendations for research and interventions to address this neglected population...
March 15, 2018: Epidemiologic Reviews
https://www.readbyqxmd.com/read/29532735/-in-the-north-you-can-t-be-openly-gay-contextualising-sexual-practices-among-sexually-and-gender-diverse-persons-in-northern-canada
#10
Carmen H Logie, Candice L Lys, Nicole Schott, Lisa Dias, Makenzie R Zouboules, Kayley Mackay
Scant research has addressed health and well-being among lesbian, gay, bisexual, transgender, and queer (LGBTQ) persons in the Arctic. The Northwest Territories (NWT) has among Canada's highest rates of sexually transmitted infections (STIs). LGBTQ persons in NWT are at the nexus of LGBTQ and Arctic health disparities. Yet little is known of their sexual health needs. This qualitative study explored the sexual health needs of LGBTQ persons in the NWT. We conducted semi-structured, in-depth interviews with 51 participants, including 16 LGBTQ youth aged 15-24, 21 LGBTQ adults aged 25 and above, and 14 key informants who worked with LGBTQ persons...
March 13, 2018: Global Public Health
https://www.readbyqxmd.com/read/29509889/effects-of-pre-exposure-prophylaxis-for-the-prevention-of-hiv-infection-on-sexual-risk-behavior-in-men-who-have-sex-with-men-a-systematic-review-and-meta-analysis
#11
Michael W Traeger, Sophia E Schroeder, Edwina J Wright, Margaret E Hellard, Vincent J Cornelisse, Joseph S Doyle, Mark A Stoové
Background: HIV pre-exposure prophylaxis (PrEP) is effective in reducing HIV risk in men who have sex with men (MSM). However concerns remain that risk compensation in PrEP users may lead to decreased condom use and increased incidence of sexually transmitted infections (STIs). We assessed the impact of PrEP on sexual risk outcomes in MSM. Methods: We conducted a systematic review of open-label trials and observational studies published to August 2017 reporting sexual risk outcomes (STI diagnoses, condom use, number of sexual partners) in the context of daily oral PrEP use in HIV-negative MSM and transgender women...
March 2, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29479550/sexually-transmitted-infections-among-hiv-infected-individuals-in-the-district-of-columbia-and-estimated-hiv-transmission-risk-data-from-the-dc-cohort
#12
Jose Lucar, Rachel Hart, Nabil Rayeed, Arpi Terzian, Amy Weintrob, Marc Siegel, David M Parenti, Leah E Squires, Rush Williams, Amanda D Castel, Debra A Benator
Background: Washington, DC, has one of the highest rates of HIV infection in the United States. Sexual intercourse is the leading mode of HIV transmission, and sexually transmitted infections (STIs) are a risk factor for HIV acquisition and transmission. Methods: We evaluated the incidence and demographic factors associated with chlamydia, gonorrhea, and syphilis among HIV-infected persons enrolled at 13 DC Cohort sites from 2011 to 2015. Using Poisson regression, we assessed covariates of risk for incident STIs...
February 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29467098/retention-engagement-and-adherence-to-pre-exposure-prophylaxis-for-men-who-have-sex-with-men-and-transgender-women-in-prep-brasil-48-week-results-of-a-demonstration-study
#13
Beatriz Grinsztejn, Brenda Hoagland, Ronaldo I Moreira, Esper G Kallas, Jose V Madruga, Silvia Goulart, Iuri C Leite, Lucilene Freitas, Luana M S Martins, Thiago S Torres, Ricardo Vasconcelos, Raquel B De Boni, Peter L Anderson, Albert Liu, Paula M Luz, Valdiléa G Veloso
BACKGROUND: PrEP Brasil was a demonstration study to assess feasibility of daily oral tenofovir diphosphate disoproxil fumarate plus emtricitabine provided at no cost to men who have sex with men (MSM) and transgender women at high risk for HIV within the Brazilian public health system. We report week 48 pre-exposure prophylaxis (PrEP) retention, engagement, and adherence, trends in sexual behaviour, and incidence of HIV and sexually transmitted infections in this study cohort. METHODS: PrEP Brasil was a 48 week, open-label, demonstration study that assessed PrEP delivery at three referral centres for HIV prevention and care in Rio de Janeiro, Brazil (Fundação Oswaldo Cruz), and São Paulo, Brazil (Universidade de São Paulo and Centro de Referência e Treinamento em DST e AIDS)...
March 2018: Lancet HIV
https://www.readbyqxmd.com/read/29465654/hiv-co-infection-among-persons-diagnosed-with-sexually-transmitted-diseases-san-francisco-2007-2014
#14
Miao-Jung Chen, Susan Scheer, Trang Q Nguyen, Robert P Kohn, Sandy Schwarcz
BACKGROUND: Early syphilis, gonorrhea, and chlamydia but not HIV infections have increased in San Francisco, primarily among men. METHODS: We linked records of persons reported with early syphilis, gonorrhea, and chlamydia to records of persons reported with HIV to measure the proportion and characteristics of San Francisco residents with HIV-STD co-infection between 2007 and 2014. We measured trends in HIV co-infection separately for men and women for each STD...
January 16, 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29464455/-and-then-break-the-clich%C3%A3-understanding-and-addressing-hiv-vulnerability-through-development-of-an-hiv-prevention-telenovela-with-men-who-have-sex-with-men-and-transwomen-in-lima-peru
#15
Jonathan Garcia, Amaya G Perez-Brumer, Robinson Cabello, Jesse L Clark
HIV and other sexually transmitted infections (STIs) continue to affect men who have sex with men (MSM) and transgender women (TW) in Peru at disproportionately high rates. The ineffectiveness of traditional prevention strategies may be due to the disconnect between health promotion messages and community-level understandings of sexual cultures. We conducted 15 workshops with MSM and TW to develop a community-based sexual health intervention. Intervention development consisted of focus groups and scenic improvisation to identify sexual scripts for an HIV prevention telenovela, or Spanish soap opera...
February 20, 2018: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/29455719/community-engagement-and-venue-based-sampling-in-adolescent-male-sexually-transmitted-infection-prevention-research
#16
Mary A Ott, Julianne Campbell, Teresa M Imburgia, Ziyi Yang, Wanzhu Tu, Colette L Auerswald
OBJECTIVES: Middle adolescent males are a difficult group to recruit for community sexually transmitted infection (STI) prevention research. We describe a process of community engagement, and venue-based sampling of 14-17-year-old adolescent males, and compare rates of STIs and STI risk behaviors by venue. METHODS: Community engagement consisted of (1) informational meetings with organizations; (2) participation in community meetings and events; (3) hiring community members as study personnel; and (4) an adolescent advisory board recruited from the community...
March 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29420443/factors-associated-with-syphilis-testing-and-a-history-of-syphilis-infection-among-a-sample-of-transgender-women-in-jamaica
#17
Carmen H Logie, Ying Wang, Ashley Lacombe-Duncan, Uzma Ahmed, Nicolette Jones, Ava Neil, Tyrone Ellis, Kandasi Levermore, Annecka Marshall, Peter A Newman
BACKGROUND: Globally, social inequalities contribute to elevated sexually transmitted infections (STIs) rates among transgender women. High syphilis prevalence has been documented among transgender women in Latin America. Little is known, however, of syphilis testing uptake among transgender women in Jamaica, where homosexuality is criminalized. The study objective was to understand factors associated with opting-in for syphilis testing and a syphilis infection history among transgender women in Jamaica...
March 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29350112/a-comparison-of-hiv-risk-behaviors-between-young-black-cisgender-men-who-have-sex-with-men-and-young-black-transgender-women-who-have-sex-with-men
#18
Richard A Crosby, Laura F Salazar, Brandon Hill, Leandro Mena
This study compared sexually transmitted infection (STI)-associated risks between young Black cisgender men who have sex with men (YBMSM) and young Black transwomen who have sex with men (YBTWSM). Comparisons pertained to: (1) prevalence of infections; (2) sexual risk; (3) partner-related risks; and (4) socioeconomic marginalization. YBMSM (n = 577) and YBTWSM (n = 32) were recruited from an STI clinic in the USA. Volunteers completed a computer-assisted self-interview and medical records were abstracted for STI/HIV information...
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29095843/transgender-female-sex-workers-hiv-knowledge-experienced-stigma-and-condom-use-in-the-dominican-republic
#19
Henna Budhwani, Kristine R Hearld, Julia Hasbun, Rebecca Charow, Santo Rosario, Louise Tillotson, Elaine McGlaughlin, John Waters
INTRODUCTION: Not only do transgender female sex workers have some of the highest rates of sexually transmitted infections (STI), human immunodeficiency virus (HIV), and experienced stigma, they also have higher likelihood of early sexual debut and some of the lowest levels of educational attainment compared to other stigmatized populations. Some of the most common interventions designed to reduce transmission of HIV and STIs seek to educate high-risk groups on sexual health and encourage condom use across all partner types; however, reaching stigmatized populations, particularly those in resource-limited settings, is particularly challenging...
2017: PloS One
https://www.readbyqxmd.com/read/29091340/online-interventions-to-address-hiv-and-other-sexually-transmitted-and-blood-borne-infections-among-young-gay-bisexual-and-other-men-who-have-sex-with-men-a-systematic-review
#20
REVIEW
Rod Knight, Mohammad Karamouzian, Travis Salway, Mark Gilbert, Jean Shoveller
INTRODUCTION: Globally, young gay, bisexual and other men who have sex with men (gbMSM) continue to experience disproportionately high rates of HIV and other sexually transmitted and blood-borne infections (STBBIs). As such, there are strong public health imperatives to evaluate innovative prevention, treatment and care interventions, including online interventions. This study reviewed and assessed the status of published research (e.g. effectiveness; acceptability; differential effects across subgroups) involving online interventions that address HIV/STBBIs among young gbMSM...
November 2017: Journal of the International AIDS Society
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