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https://www.readbyqxmd.com/read/28343067/reading-problems-and-major-mental-disorders-co-occurrences-and-familial-overlaps-in-a-swedish-nationwide-cohort
#1
Martin Cederlöf, Barbara Maughan, Henrik Larsson, Brian M D'Onofrio, Robert Plomin
Reading problems often co-occur with ADHD and conduct disorder. However, the patterns of co-occurrence and familial overlap between reading problems and other psychiatric disorders have not been systematically explored. We conducted a register-based cohort study including 8719 individuals with reading problems and their siblings, along with matched comparison individuals. Conditional logistic regressions estimated risks for ADHD, autism, obsessive-compulsive disorder, anorexia nervosa, schizophrenia, bipolar disorder, depression, substance use disorder, and violent/non-violent criminality in individuals with reading problems and their siblings...
March 21, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28342401/sudden-gains-in-exposure-therapy-for-obsessive-compulsive-disorder
#2
Lindsey M Collins, Meredith E Coles
Prior research in the treatment of depression and anxiety has demonstrated that a sudden reduction in symptoms between two consecutive sessions (sudden gain) is related to lower post-treatment symptom severity (e.g. Hofmann, Schulz, Meuret, Moscovitch, & Suvak, 2006; Tang & DeRubeis, 1999). However, only one study has examined sudden gains in the treatment of obsessive compulsive disorder (OCD). In that study, one-third of the patients with OCD experienced a sudden gain (Aderka et al., 2012). Further, patients who had a sudden gain had lower clinician-rated OCD symptom severity post-treatment (Aderka et al...
March 19, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28340445/an-updated-meta-analysis-short-term-therapeutic-effects-of-repeated-transcranial-magnetic-stimulation-in-treating-obsessive-compulsive-disorder
#3
REVIEW
Dong-Dong Zhou, Wo Wang, Gao-Mao Wang, Da-Qi Li, Li Kuang
BACKGROUND: This study was conducted to evaluate the short-term therapeutic effects of using repeated transcranial magnetic stimulation (rTMS) to treat obsessive-compulsive disorder (OCD) and to examine potential influencing factors. METHOD: We searched the PubMed, EMBASE, CENTRAL, Wanfang, CNKI, and Sinomed databases on September 18, 2016 and reviewed the references of previous meta-analyses. Sham-controlled, randomized clinical trials using rTMS to treat OCD were included...
March 18, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28339164/are-schizophrenia-autistic-and-obsessive-spectrum-disorders-dissociable-on-the-basis-of-neuroimaging-morphological-findings-a-voxel-based-meta-analysis
#4
Franco Cauda, Tommaso Costa, Andrea Nani, Luciano Fava, Sara Palermo, Francesca Bianco, Sergio Duca, Karina Tatu, Roberto Keller
Schizophrenia spectrum disorder (SCZD), autism spectrum disorder (ASD), and obsessive-compulsive spectrum disorder (OCSD) are considered as three separate psychiatric conditions with, supposedly, different brain alterations patterns. From a neuroimaging perspective, this meta-analytic study aimed to address whether this nosographical differentiation is actually supported by different brain patterns of gray matter (GM) or white matter (WM) morphological alterations. We explored two possibilities: (a) to find out whether GM alterations are specific for SCZD, ASD, and OCSD; and (b) to associate the identified brain alteration patterns with cognitive dysfunctions by means of an analysis of lesion decoding...
March 24, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28339122/mortality-risk-in-a-nationwide-cohort-of-individuals-with-tic-disorders-and-with-tourette-syndrome
#5
Sandra M Meier, Søren Dalsgaard, Preben B Mortensen, James F Leckman, Kerstin J Plessen
BACKGROUND: Few studies have investigated mortality risk in individuals with tic disorders. METHODS: We thus measured the risk of premature death in individuals with tic disorders and with Tourette syndrome in a prospective cohort study with 80 million person-years of follow-up. We estimated mortality rate ratios and adjusted for calendar year, age, sex, urbanicity, maternal and paternal age, and psychiatric disorders to compare individuals with and without tic disorders...
March 24, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28338440/a-study-of-cognitive-function-in-treatment-refractory-obsessive-compulsive-disorder-treated-with-capsulotomy
#6
Feilong Gong, Peng Li, Bin Li, Shizhen Zhang, Xinjie Zhang, Sen Yang, Hongbin Liu, Wei Wang
OBJECTIVE Anterior capsulotomy (AC) is sometimes used as a last resort for treatment-refractory obsessive-compulsive disorder (OCD). Previous studies assessing neuropsychological outcomes in patients with OCD have identified several forms of cognitive dysfunction that are associated with the disease, but few have focused on changes in cognitive function in OCD patients who have undergone surgery. In the present study, the authors investigated the effects of AC on the cognitive function of patients with treatment-refractory OCD...
March 24, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28338269/silymarin-for-the-treatment-of-obsessive-compulsive-disorders-in-dermatology
#7
Katlein França, Torello Lotti
No abstract text is available yet for this article.
March 24, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28335874/course-of-tourette-syndrome-and-comorbidities-in-a-large-prospective-clinical-study
#8
Camilla Groth, Nanette Mol Debes, Charlotte Ulrikka Rask, Theis Lange, Liselotte Skov
OBJECTIVE: Tourette syndrome (TS) is a childhood-onset neurodevelopmental disorder characterized by tics and frequent comorbidities. Although tics often improve during adolescence, recent studies suggest that comorbid obsessive-compulsive disorder (OCD) and attention-deficit/hyperactivity disorder (ADHD) tend to persist. This large prospective follow-up study describes the clinical course of tics and comorbidities during adolescence and the prevalence of coexisting psychopathologies. METHOD: The clinical cohort was recruited at the Danish National Tourette Clinic, and data were collected at baseline (n = 314, age range 5-19 years) and at follow-up 6 years later (n = 227) to establish the persistence and severity of tics and comorbidities...
April 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28334708/repetitive-transcranial-magnetic-stimulation-improved-symptoms-of-obsessive-compulsive-disorders-but-not-executive-functions-results-from-a-randomized-clinical-trial-with-crossover-design-and-sham-condition
#9
Mehran Shayganfard, Leila Jahangard, Marzieh Nazaribadie, Mohammad Haghighi, Mohammad Ahmadpanah, Dena Sadeghi Bahmani, Hafez Bajoghli, Edith Holsboer-Trachsler, Serge Brand
OBJECTIVE: Whereas there is growing evidence that repetitive transcranial magnetic stimulation (rTMS) favorably impacts on symptoms of obsessive-compulsive disorders (OCD), less is known regarding the influence of rTMS on cognitive performance of patients with OCD. Here, we tested the hypothesis that rTMS has a positive impact both on symptom severity and executive functions in such patients. METHODS: We assessed 10 patients diagnosed with OCD (mean age: 33.5 years) and treated with a standard medication; they were randomly assigned either to a treatment-first or to a sham-first condition...
March 24, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/28331571/clinical-evaluation-of-autistic-symptoms-in-women-with-anorexia-nervosa
#10
Heather Westwood, William Mandy, Kate Tchanturia
BACKGROUND: Despite a suggested link between anorexia nervosa (AN) and autism spectrum disorder (ASD), previous studies have used self-report or diagnostic criteria to assess for ASD in AN populations, rather than direct observation of symptom characteristic of ASD. The aim of this study was to use a standardised, clinical assessment of ASD, the Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2), to investigate the presence of autistic symptoms in a cross-sectional sample of women with AN...
2017: Molecular Autism
https://www.readbyqxmd.com/read/28331505/fear-of-vomiting-and-low-body-weight-in-two-pediatric-patients-diagnostic-challenges
#11
Charlotte Maertens, Jennifer Couturier, Christina Grant, Natasha Johnson
Fear of vomiting can be a symptom associated with several disorders, including Eating Disorders (ED), Specific Phobia (Emetophobia), Avoidant Restrictive Food Intake Disorder (ARFID) and Obsessive Compulsive Disorder (OCD), making proper diagnosis challenging. At this time the literature exploring this symptom is limited, and to our knowledge very few cases have been described in the child and adolescent population. We report here the cases of one child and one adolescent presenting with significant weight loss, food restriction and fear of vomiting...
2017: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28331322/the-role-of-deep-brain-stimulation-in-parkinson-s-disease-an-overview-and-update-on-new-developments
#12
REVIEW
John Y Fang, Christopher Tolleson
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the loss of neuronal dopamine production in the brain. Oral therapies primarily augment the dopaminergic pathway. As the disease progresses, more continuous delivery of therapy is commonly needed. Deep brain stimulation (DBS) has become an effective therapy option for several different neurologic and psychiatric conditions, including PD. It currently has US Food and Drug Administration approval for PD and essential tremor, as well as a humanitarian device exception for dystonia and obsessive-compulsive disorder...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28326752/minimal-role-of-comorbid-personality-disorder-on-the-quality-of-life-in-patients-with-anxiety-spectrum-disorders
#13
Dana Kamaradova, Klara Latalova, Jan Prasko, Ales Grambal, Zuzana Sigmundova, Petra Kasalova, Snezana Cakirpaloglu
OBJECTIVES: There is no consensus on the definition of Quality of life (QoL). It is considered to be comprised of both psychological and somatical well-being. A variety of tools has been developed to measure subjective and objective (QoL). A number of factors, including demographical and medical may have an impact on QoL. The aim of our study was to compare the QoL in selected anxiety disorders and evaluate the influence of comorbid personality disorder. METHOD: We evaluated data from 278 patients suffering from social phobia, panic disorder and/or agoraphobia, adjustment disorder, generalized anxiety disorder and obsessive-compulsive disorder...
January 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28322616/how-individuals-with-body-dysmorphic-disorder-bdd-process-their-own-face-a-quantitative-and-qualitative-investigation-based-on-an-eye-tracking-paradigm
#14
Wei Lin Toh, David J Castle, Susan L Rossell
INTRODUCTION: Body dysmorphic disorder (BDD) is characterised by repetitive behaviours and/or mental acts occurring in response to preoccupations with perceived flaws in physical appearance. Based on an eye-tracking paradigm, this study aimed to examine how individuals with BDD processed their own face. METHODS: Participants were 21 BDD patients, 19 obsessive-compulsive disorder patients and 21 healthy controls (HC), who were age-, sex-, and IQ-matched. Stimuli were photographs of participants' own faces as well as those from the Pictures of Facial Affect battery...
March 21, 2017: Cognitive Neuropsychiatry
https://www.readbyqxmd.com/read/28322166/glutamate-modulating-drugs-as-a-potential-therapeutic-strategy-in-obsessive-compulsive-disorder
#15
Zoya Marinova, De-Maw Chuang, Naomi Fineberg
OBJECTIVE: Obsessive-compulsive disorder (OCD) is a mental disease commonly associated with severe distress and impairment of social functioning. Serotonin reuptake inhibitors and/or cognitive behavioural therapy are the therapy of choice, however up to 40% of patients do not respond to treatment. Glutamatergic signalling has also been implicated in OCD. The aim of the current study was to review the clinical evidence for therapeutic utility of glutamate-modulating drugs as an augmentation or monotherapy in OCD patients...
March 20, 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28321149/family-and-friendship-networks-and-obsessive-compulsive-disorder-among-african-americans-and-black-caribbeans
#16
Joseph A Himle, Robert Joseph Taylor, Ann W Nguyen, Monnica T Williams, Karen D Lincoln, Harry Owen Taylor, Linda M Chatters
Although there is a large literature on the influence of social support on mental health there is limited research on social support and OCD. This is especially the case for African Americans and Black Caribbeans. This study examines the relationship between family and friendship networks and the prevalence of OCD. The analysis is based on the National Survey of American Life a nationally representative sample of African Americans and Black Caribbeans. Variables included frequency of contact with family and friends, subjective closeness with family and friends, and negative interactions (conflict, criticisms) with family members...
March 2017: Behavior Therapist
https://www.readbyqxmd.com/read/28320191/c9orf72-hexanucleotide-repeat-expansions-are-not-a-common-cause-of-obsessive-compulsive-disorder
#17
Karissa C Arthur, Alberto M Rivera, Jack Samuels, Ying Wang, Marco Grados, Fernando S Goes, Brion Maher, Gerald Nestadt, Bryan J Traynor
Obsessive-compulsive disorder (OCD) is a polygenic neuropsychiatric disorder characterized by repetitive thoughts and behaviors that cause distress. The pathogenic repeat expansion [GGGGCC]n found at the C9orf72 locus is the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), and has also been documented in patients with psychosis and schizophrenia. Furthermore, obsessions and compulsions have been identified in patients diagnosed with ALS and/or FTD and carrying the pathogenic repeat expansion...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28319785/the-long-and-complex-road-in-the-search-for-treatment-for-mental-disorders-an-analysis-of-the-process-in-five-groups-of-patients
#18
Gema Del Valle, Amparo Belloch, Carmen Carrió
Seeking treatment for mental-health problems is a complex process, with different underlying motives in each stage. However, the entire process and these motives have hardly been investigated. This study aims to analyze the different stages of the help-seeking process and their underlying motives in five groups of patients with different mental disorders. In all, 156 patients seeking treatment in outpatient mental health clinics were individually interviewed: 71 had Obsessive-Compulsive Disorder (OCD), 21 had Agoraphobia (AGO), 18 had Major Depressive Disorder (MDD), 20 had Anorexia Nervosa (AN), and 22 had Cocaine Dependence (COC)...
March 15, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28303109/the-effect-of-abuse-history-on-adolescent-patients-with-feeding-and-eating-disorders-treated-through-psychodynamic-therapy-comorbidities-and-outcome
#19
Annamaria M Strangio, Lucio Rinaldi, Gianluigi Monniello, Leuconoe Grazia Sisti, Chiara de Waure, Luigi Janiri
OBJECTIVES: The first aim of our study was to compare the characteristics and comorbidities of patients with eating disorders between those who suffered from a childhood abuse and those who did not. Our second aim was to analyze the differences in the outcome of the psychodynamic therapy between abused and not abused patients. METHODS: Twenty-six adolescent patients with eating disorders were assessed. Adolescent were evaluated by a single expert psychiatrist by checklists and questionnaires: EDI 3, SCL 90, BIS11, Dissociative Experiences Scale, Global Assessment of Functioning, SCID II, and CTQ-Self control (SF)...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28302189/temporal-dynamics-of-rituals-in-obsessive-compulsive-disorder
#20
Robert W Bond, Stephen J Guastello, Andrea D Guastello
Obsessive-compulsive disorder (OCD) is characterized by obsessions, defined as intrusive and persistent thoughts, and compulsions, defined as repetitive ritualistic behaviors that attempt to neutralize the anxiety associated with the obsessions. The present study investigated the patterns of symptoms as they occur over time in order to generate new insights about the triggers to symptoms. Fourteen adult participants who met the DSM-5 criteria for OCD completed 7-day logbooks of daily activities including the times when they engaged in compulsive rituals...
April 2017: Nonlinear Dynamics, Psychology, and Life Sciences
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