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Neuro radiology

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https://www.readbyqxmd.com/read/29752700/neuro-radiological-features-can-predict-hypopituitarism-in-primary-autoimmune-hypophysitis
#1
Tommaso Tartaglione, Sabrina Chiloiro, Maria Elena Laino, Antonella Giampietro, Simona Gaudino, Angelo Zoli, Antonio Bianchi, Alfredo Pontecorvi, Cesare Colosimo, Laura De Marinis
Primary autoimmune hypophysitis (PAH) is considered an underdiagnosed disease, due to the difficulty in reaching a definitive diagnosis. PAH clinical diagnosis remains an exclusion diagnosis. We aimed to correlate PAH neuro-radiological signs to endocrine features and evaluate their prognostic role. 24 PAH cases were enrolled and classified according to neuro-radiological signs: in 12 adeno-hypophysitis (AHs), 8 infundibulo-neuro-hypophysitis (INHs) and 4 pan-hypophysitis (PHs). Secondary hypogonadism developed more frequently in INHs as compared to AHs (54...
May 11, 2018: Pituitary
https://www.readbyqxmd.com/read/29709755/the-outcomes-of-pituitary-apoplexy-with-conservative-treatment-experiences-at-a-single-institution
#2
Youngbeom Seo, Yong Hwy Kim, Yun-Sik Dho, Jung Hee Kim, Jin Wook Kim, Chul-Kee Park, Dong Gyu Kim
OBJECTIVE: Pituitary apoplexy is an unpredictable complication caused by hemorrhage or infarction in a pituitary adenoma. We retrospectively analyzed the radiological and clinical outcomes of patients with conservatively managed pituitary apoplexy. METHODS: A total of 32 patients who had undergone conservative treatment with high-dose corticosteroid replacement were enrolled in this study. This cohort study consisted of 20 male and 12 female patients. The median patient age was 60 years...
April 27, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29682076/neurocysticercosis-in-japan
#3
Victor Kwasi, Kunihiko Kodama, Toshiya Uchiyama, Yoshikazu Kusano, Toshiyuki Shimizu, Kazuo Tokushige, Toshiki Takemae
Neurocysticercosis is a condition rarely reported in Japan, and therefore, the specific route of infestation in our set up has not been conclusively elucidated. Preoperative diagnosis remains difficult to make with certainty due to the slowly evolving nature of the disease and the fact that there are no typical characteristic clinical findings particularly associated with the disease. The hematological, serological, serum biochemistry, stool, and radiological tests were nonspecific for neurocysticercosis. The characteristic neuro-imaging findings were demonstrated in this case, and histopathology confirmed Taenia solium parenchymal infestation...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29675083/neuroimaging-in-menkes-disease
#4
Molla I Ahmed, Nahin Hussain
Menkes disease (MD) is a rare infantile onset neurodegenerative disorder due to mutations in the X linked ATP7A gene. These patients can present with failure to thrive, severe psychomotor retardation, seizures and hypopigmented hair, which is characteristic of this condition. A number of neuro-radiological findings have been reported in this condition. We report the spectrum of neuro-radiological findings in three affected boys being treated at our centre. We suggest that magnetic resonance imaging (MRI) and, in particular magnetic resonance angiography (MRA) when taken in the context of the clinical presentation may be helpful in making an early diagnosis of this devastating condition...
October 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29674411/sequential-apparent-diffusion-coefficient-for-assessment-of-tumor-progression-in-patients-with-low-grade-glioma
#5
I E Chen, N Swinburne, N M Tsankova, M M Hefti, A Aggarwal, A H Doshi, A Hormigo, B N Delman, K Nael
BACKGROUND AND PURPOSE: Early and accurate identification of tumor progression in patients with low-grade gliomas is challenging. We aimed to assess the role of quantitative ADC analysis in the sequential follow-up of patients with low-grade gliomas as a potential imaging marker of tumor stability or progression. MATERIALS AND METHODS: In this retrospective study, patients with a diagnosis of low-grade glioma with at least 12 months of imaging follow-up were retrospectively reviewed...
April 19, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29644808/prognostic-evaluation-of-neurological-assessment-of-the-neuro-oncology-scale-in-glioblastoma-patients
#6
Jiwook Lee, Sung Hyun Park, Young Zoon Kim
BACKGROUND: The aims of this study were to investigate the role of the Neurological Assessment of Neuro-Oncology (NANO) scale in predicting the prognosis of patients with glioblastoma, and compare these results to predicted data of the Karnofsky Performance Scale (KPS), and Eastern Cooperative Oncology Group (ECOG)/World Health Organization (WHO) performance status. Additionally, we examined other prognostic factors in glioblastoma patients. METHODS: The medical records of 76 patients with a new diagnosis of histologically ascertained glioblastoma in the period from January 2002 to December 2015 at the authors' institution were retrospectively reviewed...
April 2, 2018: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29618103/the-neurologic-assessment-in-neuro-oncology-nano-scale-as-an-assessment-tool-for-survival-in-patients-with-primary-glioblastoma
#7
Timothy H Ung, Douglas E Ney, Denise Damek, Chad G Rusthoven, A Samy Youssef, Kevin O Lillehei, D Ryan Ormond
BACKGROUND: The Neurologic Assessment in Neuro-Oncology (NANO) scale is a standardized objective metric designed to measure neurological function in neuro-oncology. Current neuroradiological evaluation guidelines fail to use specific clinical criteria for progression. OBJECTIVE: To determine if the NANO scale was a reliable assessment tool in glioblastoma (GBM) patients and whether it correlated to survival. METHODS: Our group performed a retrospective review of all patients with newly diagnosed GBM from January 1, 2010, through December 31, 2012, at our institution...
March 30, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29508764/working-plan-for-the-use-of-patient-reported-outcome-measures-in-adults-with-brain-tumours-a-response-assessment-in-neuro-oncology-rano-initiative
#8
REVIEW
Linda Dirven, Terri S Armstrong, Jaishri O Blakeley, Paul D Brown, Robin Grant, Rakesh Jalali, Heather Leeper, Tito Mendoza, Lakshmi Nayak, Jaap C Reijneveld, Emilie Le Rhun, Tobias Walbert, Michael Weller, Patrick Y Wen, Martin J B Taphoorn
The Response Assessment in Neuro-Oncology-Patient-Reported Outcome (RANO-PRO) working group is an international multidisciplinary collaboration that provides guidance on the use of patient-reported outcome (PRO) measures in clinical trials and practice for adult patients with brain tumours. Findings from both PROs and traditional outcome measures, such as survival, and clinical or radiological response, are essential to inform the research community, policy makers, physicians, and patients in the treatment decision-making process...
March 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29492925/predictive-factors-of-urinary-incontinence-after-radical-prostatectomy-systematic-review
#9
Sataa Sallami
PURPOSE: To determine the predictive factors of urinary incontinence (UI) after radical prostatectomy (RP) for localized prostate cancer. METHODS: Review of the French and English literature between 1996 and 2015 treating risk factors of UI after RP. RESULTS: We identified 46 articles to be analyzed. Preoperative risk factors of UI were age, BMI, prostate surgery history, the sphincter deficit, bladder instability, the quality of the surgical technique (preservation of neuro-vacsulaire strips, blood loss) The morphology of the prostate on MRI and the importance of the loss of urine after the removal of the bladder catheter...
April 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/29475379/transmastoid-implantability-of-an-active-transcutaneous-bone-conduction-implant-in-adults-with-regard-to-the-underlying-pathology-a-radiological-simulation-study
#10
Jan Peter Thomas, Konstantin van Ackeren, Stefan Dazert, Ingo Todt, Andreas Prescher, Christiane Voelter
OBJECTIVES: To compare the feasibility of transmastoid implantation of an active transcutaneous bone conduction device (BCD) in the most important pathologies of the temporal bone and the impact of implant lifts in adulthood. METHODS: First, clinical predominant pathologies for implantation of this BCD were evaluated by a literature review. Then, high-resolution CT of 240 temporal bones with neuro-otologic diseases (NOD), chronic otitis media (COM), or cholesteatoma, respectively, were investigated regarding their implantability, using a radiological simulation program...
June 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29475026/results-of-interdisciplinary-management-of-693-patients-with-aneurysmal-subarachnoid-hemorrhage-clinical-outcome-and-relevant-prognostic-factors
#11
Muhammad AlMatter, Marta Aguilar Péreza, Pervinder Bhogal, Victoria Hellstern, Oliver Ganslandt, Hans Henkes
OBJECTIVES: Aneurysmal subarachnoid hemorrhage (aSAH) is associated with high rates of morbidities and fatalities. The continuous evolution of neurosurgical, endovascular and neuro-intensive cares has improved the overall mortality. In this study we sought to evaluate the clinical outcome after aSAH from a single tertiary center. PATIENTS AND METHODS: We retrospectively identified and reviewed all consecutive patients with aSAH treated at our center between 2007 and 2016...
April 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29459844/magnetic-resonance-spectroscopy-positron-emission-tomography-and-radiogenomics-relevance-to-glioma
#12
REVIEW
Gloria C Chiang, Ilhami Kovanlikaya, Changho Choi, Rohan Ramakrishna, Rajiv Magge, Dikoma C Shungu
Advances in metabolic imaging techniques have allowed for more precise characterization of gliomas, particularly as it relates to tumor recurrence or pseudoprogression. Furthermore, the emerging field of radiogenomics where radiographic features are systemically correlated with molecular markers has the potential to achieve the holy grail of neuro-oncologic neuro-radiology, namely molecular diagnosis without requiring tissue specimens. In this section, we will review the utility of metabolic imaging and discuss the current state of the art related to the radiogenomics of glioblastoma...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29459606/clinical-and-neuro-radiological-presentation-of-tuberous-sclerosis-complex-in-tertiary-care-centre
#13
G K Kundu, S Ahmed, S Akhter, M T Islam, T Dwa, A M Sabbir
Tuberous sclerosis complex (TSC) is a common neurocutaneous disorder characterized by hamartomatous changes in the lungs, brain, kidneys, skin, heart, and other organs. This retrospective study was done to see the clinical presentation and neuro imaging pattern of TSC in a tertiary care centre of Bangladesh and was conducted at Pediatric Neurology Unit of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from January 2013 to December 2013. Among total 10 patients male-female ratio was 3:2...
January 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29434566/assessment-of-platelet-function-in-traumatic-brain-injury-a-retrospective-observational-study-in-the-neuro-critical-care-setting
#14
Caroline Lindblad, Eric Peter Thelin, Michael Nekludov, Arvid Frostell, David W Nelson, Mikael Svensson, Bo-Michael Bellander
Background: Despite seemingly functional coagulation, hemorrhagic lesion progression is a common and devastating condition following traumatic brain injury (TBI), stressing the need for new diagnostic techniques. Multiple electrode aggregometry (MEA) measures platelet function and could aid in coagulopathy assessment following TBI. The aims of this study were to evaluate MEA temporal dynamics, influence of concomitant therapy, and its capabilities to predict lesion progression and clinical outcome in a TBI cohort...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29433183/quality-of-life-after-craniovertebral-junction-meningioma-resection-shaping-the-real-neurologic-and-functional-expectancies-about-these-surgeries-in-a-contemporary-large-multicenter-experience
#15
Antonino Raco, Alessandro Pesce, Giada Toccaceli, Alessandro Frati, Demo Eugenio Dugoni, Roberto Delfini
OBJECTIVE: Craniovertebral junction (CVJ) meningiomas are one of the most surgically complex conditions in neuro-oncologic surgery. The aim of this work is to correlate our data with clinical outcome to outline factors leading to a worse functional prognosis. METHODS: We analyzed sex, age, clinical presentation, topography, surgical approach, Simpson grade resection, postoperative lower cranial nerve deficits, consistency, histology, site of origin, presence of a capsule, and radiologic and clinical follow-up at 1, 6, and 12 months of 61 patients affected by CVJ meningiomas, operated on in our institution from 1992 to 2014...
February 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29425986/is-edema-a-matter-of-concern-after-laser-ablation-of-epileptogenic-focus
#16
Vivek Tandon, Michael Lang, Poodipedi Sarat Chandra, Ashwini Sharan, Ajay Garg, Manjari Tripathi
BACKGROUND: A stereotactically placed laser fiber can deliver thermal energy to an epileptogenic focus in the brain. This procedure is done under intraoperative (thermography) magnetic resonance imaging (MRI) guidance. Thermoablation can lead to edema in the surrounding area and can cause a secondary insult. In this report of 3 cases, we have quantified the edema produced after laser ablation by sequential MRI in the immediate postoperative period. CASE DESCRIPTIONS: Three patients with intractable epilepsy underwent a detailed neurologic and neuroradiologic workup to localize the site of epileptogenic foci...
May 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29370869/a-new-enzyme-linked-immunosorbent-assay-for-neurofilament-light-in-cerebrospinal-fluid-analytical-validation-and-clinical-evaluation
#17
Lorenzo Gaetani, Kina Höglund, Lucilla Parnetti, Fani Pujol-Calderon, Bruno Becker, Paolo Eusebi, Paola Sarchielli, Paolo Calabresi, Massimiliano Di Filippo, Henrik Zetterberg, Kaj Blennow
BACKGROUND: Cerebrospinal fluid (CSF) neurofilament light (NfL) is a reliable marker of neuro-axonal damage in different neurological disorders that is related to disease severity. To date, all recent studies performed in human CSF have used the same enzyme-linked immunosorbent assay (ELISA). To confirm the large body of evidence for NfL, we developed a new ELISA method and here we present the performance characteristics of this new ELISA for CSF NfL in different neurological disorders...
January 23, 2018: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/29352231/the-direction-of-tumour-growth-in-glioblastoma-patients
#18
Morteza Esmaeili, Anne Line Stensjøen, Erik Magnus Berntsen, Ole Solheim, Ingerid Reinertsen
Generating MR-derived growth pattern models for glioblastoma multiforme (GBM) has been an attractive approach in neuro-oncology, suggesting a distinct pattern of lesion spread with a tendency in growing along the white matter (WM) fibre direction for the invasive component. However, the direction of growth is not much studied in vivo. In this study, we sought to study the dominant directions of tumour expansion/shrinkage pre-treatment. We examined fifty-six GBMs at two time-points: at radiological diagnosis and as part of the pre-operative planning, both with contrast-enhanced T1-weighted MRIs...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29286511/cerebral-impact-of-prenatal-irradiation-by-131i-an-experimental-model-of-clinical-neuroradioembryological-effects
#19
V V Talko, K M Loganovsky, I P Drozd, Ye V Tukalenko, T K Loganovska, S Yu Nechayev, S V Masiuk, Ye M Prokhorova
Human brain in prenatal period is a most vulnerable to ionizing radiation body structure. Unlike atomic bombings or radiological interventions in healthcare leading at most to external irradiation the intensive internal exposure may occur upon nuclear reactor accidents followed by substantial release and fallout of radioactive 131I. The latter can lead to specific neuroradioembryological effects. OBJECTIVE: To create an experimental model of prenatal cerebral radiation effects of 131I in human and to determine the experimental and clinical neuroradioembryological effects...
December 2017: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://www.readbyqxmd.com/read/29283100/the-efficacy-of-magnetic-resonance-imaging-for-the-diagnosis-of-superior-semicircular-canal-dehiscence
#20
Fatma Beyazal Çeliker, Abdulkadir Özgür, Metin Çeliker, Mehmet Beyazal, Arzu Turan, Suat Terzi, Mehmet Fatih İnecikli
OBJECTIVE: This study aimed to evaluate the efficacy of magnetic resonance imaging (MRI) for diagnosing superior semicircular canal dehiscence (SSCD). MATERIALS AND METHODS: The radiological records of patients who were admitted to our clinic with complaints of otologic and neuro-otologic symptoms between October 2014 and December 2015 were retrospectively reviewed. Among these patients, those who underwent both computed tomography and MRI and were reported to have SSCD in the temporal bone on at least one side were included in the study group...
December 14, 2017: Journal of International Advanced Otology
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