keyword
https://read.qxmd.com/read/38544291/extra-prostatic-extension-epe-grading-system-correlation-with-mri-features-and-integration-of-capsular-enhancement-sign-ces-for-enhanced-detection-of-t3a-lesions
#1
JOURNAL ARTICLE
Federica Martini, Maria Pigati, Matilde Mattiauda, Marta Ponzano, Nataniele Piol, Simona Pigozzi, Bruno Spina, Giuseppe Cittadini, Veronica Giasotto, Jeries Paolo Zawaideh
PURPOSE: This study aims to confirm the diagnostic accuracy of extra-prostatic extension (EPE) grading system and to explore the predictive capabilities of the prostate MRI while considering various MRI features such as lesion location, ADC values and capsular enhancement sign (CES). MATERIALS AND METHODS: Our monocentric study is based on a retrospective analysis of 99 patients who underwent radical prostatectomy from January 2021 to January 2023. The observers reviewed for each lesion, including location (transitional or peripheral zone, anterior or posterior location), capsular contact length, irregular bulging of the capsule, asymmetry of the neuro-vascular bundle, obliteration of the recto-prostatic angle, macroscopic EPE, ADC value, and CES...
March 27, 2024: British Journal of Radiology
https://read.qxmd.com/read/38525561/structural-mri-measures-are-associated-with-fatigue-severity-and-persistence-in-a-large-real-world-cohort-of-people-with-multiple-sclerosis
#2
JOURNAL ARTICLE
Alexandra C Simpson, Chen Hu, Ellen M Mowry, Robert T Naismith, Kathryn C Fitzgerald, Bardia Nourbakhsh
BACKGROUND: Results of research on radiological hallmarks of multiple sclerosis (MS) fatigue have been conflicting. OBJECTIVE: To investigate the associations of lesion and brain compartment volumes with fatigue severity and persistence in people with multiple sclerosis (PwMS). METHODS: The Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS) network collects standardized data during routine care of PwMS from 10 healthcare institutions...
March 25, 2024: Multiple Sclerosis: Clinical and Laboratory Research
https://read.qxmd.com/read/38518385/radiologically-derived-3d-virtual-models-for-neurosurgical-planning
#3
JOURNAL ARTICLE
Hyun-Jae Cho, Thomas Lloyd, Adrian Zammit, Ananthababu Pattavilakom Sadasivan, Michael Wagels, Allison Sutherland
Three dimensional (3D) virtual models for neurosurgery have demonstrated substantial clinical utility, especially for neuro-oncological cases. Computer-aided design (CAD) modelling of radiological images can provide realistic and high-quality 3D models which neurosurgeons may use pre-operatively for surgical planning. 3D virtual models are useful as they are the basis for other models that build off this design. 3D virtual models are quick to segment but can also be easily added to normal neurosurgical and radiological workflow without disruption...
March 21, 2024: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://read.qxmd.com/read/38507506/insights-from-a-multicenter-study-on-adult-h3-k27m-mutated-glioma-surgical-resection-s-limited-influence-on-overall-survival-atrx-as-molecular-prognosticator
#4
JOURNAL ARTICLE
A Ryba, Z Özdemir, N Nissimov, L Hönikl, N Neidert, M Jakobs, D Kalasauskas, A Krigers, C Thomé, C F Freyschlag, F Ringel, A Unterberg, P Dao Trong, J Beck, D H Heiland, B Meyer, P Vajkoczy, J Onken, W Stummer, E Suero Molina, J Gempt, M Westphal, U Schüller, M Mohme
BACKGROUND: H3 K27M-mutated gliomas were first described as a new grade 4 entity in the 2016 WHO classification. Current studies have focused on its typical appearance in children and young adults, increasing the need to better understand the prognostic factors and impact of surgery on adults. Here, we report a multicentric study of this entity in adults. METHODS: We included molecularly confirmed H3 K27M-mutated glioma cases in patients >18 years diagnosed between 2016 and 2022...
March 20, 2024: Neuro-oncology
https://read.qxmd.com/read/38502219/the-increasing-burden-of-emergency-department-and-inpatient-consultations-for-papilledema
#5
JOURNAL ARTICLE
Hetal J Ray, Avital Lily Okrent Smolar, Michael Dattilo, Walid Bouthour, Gabriele Berman, Jason H Peragallo, Sachin Kedar, Andrew M Pendley, James G Greene, Matthew T Keadey, David W Wright, Beau B Bruce, Nancy J Newman, Valérie Biousse
BACKGROUND: Increasing incidence of idiopathic intracranial hypertension (IIH), overreported radiologic signs of intracranial hypertension, difficult access to outpatient neuro-ophthalmology services, poor insurance coverage, and medicolegal concerns have lowered the threshold for emergency department (ED) visits for "papilledema." Our objective was to examine referral patterns and outcomes of neuro-ophthalmology ED and inpatient consultations for concern for papilledema. METHODS: At one university-based quaternary care center, all adults referred for "papilledema" over one year underwent a standardized ED "papilledema protocol...
March 19, 2024: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://read.qxmd.com/read/38496127/using-diagnostic-radiological-imaging-modalities-to-explore-neurological-dysfunction-and-renal-failure-in-the-intersection-of-hemophagocytic-lymphohistiocytosis-macrophage-activation-syndrome-and-lupus
#6
Juliana Cazzaniga, Kateryna Georgiyeva, Andrea Siguenza, Teresita Gonzalez, Pablo Ferraro
This comprehensive case report and literature review explore the intricate intersection of hemophagocytic lymphohistiocytosis (HLH), macrophage activation syndrome (MAS), and systemic lupus erythematosus (SLE) in a 39-year-old patient, emphasizing the challenging diagnostic and therapeutic landscape. The patient's journey includes neurological dysfunction, renal failure, and clinical complexities, showcasing the rarity of these overlapping conditions. The report explains the diagnostic process, clinical and laboratory findings, specialty consultations, and treatment decisions leading to the diagnosis of SLE with features of MAS overlapping with HLH...
February 2024: Curēus
https://read.qxmd.com/read/38493891/intracranial-epidermoid-cyst-a-volumetric-study-of-a-surgically-challenging-benign-lesion
#7
JOURNAL ARTICLE
Daniel Kiss-Bodolay, Xenia Hautmann, Kok Sin Lee, Veit Rohde, Karl Schaller
BACKGROUND: Intracranial epidermoid cysts are rare, benign tumors. Nevertheless, the microsurgical removal of these cysts is challenging. This is due to their capacity to adhere to the neuro-vascular tissue as well as the associated difficulties in micro-surgically peeling off their capsular wall hidden in dead angles. To better understand the rate of recurrence after surgical intervention, we have performed pre- and postoperative volumetric analysis of epidermoid cysts allowing the estimation of their growth rate after resection...
March 15, 2024: World Neurosurgery
https://read.qxmd.com/read/38492275/regoma-oss-a-large-italian-multicenter-prospective-observational-study-evaluating-the-efficacy-and-safety-of-regorafenib-in-patients-with-recurrent-glioblastoma
#8
JOURNAL ARTICLE
M Caccese, I Desideri, V Villani, M Simonelli, M Buglione, S Chiesa, E Franceschi, P Gaviani, I Stasi, C Caserta, S Brugnara, I Lolli, E Bennicelli, P Bini, A S Cuccu, S Scoccianti, M Padovan, S Gori, A Bonetti, P Giordano, A Pellerino, F Gregucci, N Riva, S Cinieri, V Internò, M Santoni, G Pernice, C Dealis, L Stievano, F Paiar, G Magni, G L De Salvo, V Zagonel, G Lombardi
BACKGROUND: In the randomized phase II REGOMA trial, regorafenib showed promising activity in patients with recurrent glioblastoma. We conducted a large, multicenter, prospective, observational study to confirm the REGOMA data in a real-world setting. PATIENTS AND METHODS: The major inclusion criteria were histologically confirmed diagnosis of glioblastoma according to the World Health Organization (WHO) 2016 classification and relapse after radiotherapy with concurrent/adjuvant temozolomide treatment, good performance status [Eastern Cooperative Oncology Group performance status (ECOG PS 0-1)] and good liver function...
March 15, 2024: ESMO Open
https://read.qxmd.com/read/38488499/gammatile-reshaping-brachytherapy
#9
JOURNAL ARTICLE
David Casper, Joel Hayden, Mayra Anthony, Nick Matthees, Raza Mushtaq
No abstract text is available yet for this article.
March 2024: Radiology. Imaging cancer
https://read.qxmd.com/read/38484938/a-comprehensive-review-of-empty-sella-and-empty-sella-syndrome
#10
REVIEW
Michelle D Lundholm, Divya Yogi-Morren
Incidental radiographic findings of an empty sella are prevalent in up to 35% of the general population. While empty sella was initially considered clinically insignificant, a subset of patients exhibits endocrine or neuro-ophthalmologic manifestations which are diagnostic of empty sella syndrome (ESS). Recent studies suggest that more patients are affected by ESS than previously recognized, necessitating a deeper understanding of this condition and an approach to evaluating and managing these patients. This comprehensive review addresses the etiologies and risk factors associated with primary and secondary empty sella, the radiological features that differentiate empty sella from other sellar lesions, and the role of clinical history and hormone testing in identifying patients with ESS...
March 12, 2024: Endocrine Practice
https://read.qxmd.com/read/38477525/advanced-imaging-in-the-diagnosis-and-response-assessment-of-high-grade-glioma-ajr-expert-panel-narrative-review
#11
REVIEW
Leland S Hu, Marion Smits, Timothy J Kaufmann, Linda Knutsson, Otto Rapalino, Norbert Galldiks, Pia C Sundgrene, Soonmee Cha
This AJR Expert Panel Narrative explores the current status of advanced MRI and PET techniques for the post-therapeutic response assessment of high-grade adult-type gliomas, focusing on ongoing clinical controversies in current practice. Discussed techniques that complement conventional MRI and aid the differentiation of recurrent tumor from post-treatment effects include DWI and diffusion tensor imaging; perfusion MRI techniques including dynamic susceptibility contrast (DSC), dynamic contrast-enhanced MRI, and arterial spin labeling; MR spectroscopy including assessment of 2-hydroxyglutarate (2HG) concentration; glucose- and amino acid (AA)-based PET; and amide proton transfer imaging...
March 13, 2024: AJR. American Journal of Roentgenology
https://read.qxmd.com/read/38469574/retinal-structure-and-vessel-density-changes-in-cerebral-small-vessel-disease
#12
JOURNAL ARTICLE
Dandan Wang, Lina Wang, Jinjin Wang, Yang Du, Kaiyue Wang, Meizi Wang, Liu Yang, Xingquan Zhao
BACKGROUND: Cerebral small vessel disease (CSVD) attaches people's attention in recent years. In this study, we aim to explore retinal structure and vessel density changes in CSVD patients. METHODS: We collected information on retinal metrics assessed by optical coherence tomography (OCT) and OCT angiography and CSVD characters. Logistic and liner regression was used to analyze the relationship between retinal metrics and CSVD. RESULTS: Vessel density of superficial retinal capillary plexus (SRCP), foveal density- 300 length (FD-300), radial peripapillary capillary (RPC) and thickness of retina were significantly lower in CSVD patients, the difference only existed in the thickness of retina after adjusted relevant risk factors (OR (95% CI): 0...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38445427/cerebral-palsy-of-the-child-in-rehabilitation-environment-epidemiologic-and-clinical-profile-and-therapeutic-modalities
#13
JOURNAL ARTICLE
Rim Maaoui, Souad Karoui, Meriem Hfaidh, Najla Mouhli, Zied Ezzine, Imene Ksibi, Hajer Rahali, Hajer Barakizou, Khouloud Hamdi
INTRODUCTION: Cerebral palsy (CP) is a group of permanent disorders of the development of movement and posture causing activity limitation. AIM: To evaluate the epidemiological, clinical, and radiological profile of children with CP and to study the therapeutic modalities in daily clinical practice. METHOD: This was a retrospective, descriptive study, carried out in a physical medicine and rehabilitation department, including all the patients referred with the diagnosis of cerebral palsy between January 2000 and December 2016...
July 5, 2023: La Tunisie Médicale
https://read.qxmd.com/read/38440533/morphometric-analysis-of-temporal-bone-radiology-for-cochlear-implant-candidacy
#14
JOURNAL ARTICLE
Vibhor Malhotra, Savith Kumar, Gayathri S Menon, Anand Hejjaji Krishnamurthy, Shankar Medikeri, Sunil Narayan Dutt
Cochlear Implantation (CI) is a well-accepted treatment for severe-to-profound sensorineural hearing loss, refractory to conventional hearing amplification. Pre-operative Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) play pivotal roles in patient selection to rule out findings that preclude surgery or identify conditions that may impact the surgical procedure. A prospective study was carried out in a tertiary care center over three years, from January 2020 to January 2023. One hundred and ninety (380 ears) patients' High-Resolution Computed Tomography (HRCT) studies of the temporal bone and MRI scans of the auditory pathways were analyzed...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38433865/artificial-intelligence-enabled-ophthalmoscopy-for-papilledema-a-systematic-review-protocol
#15
JOURNAL ARTICLE
Lekaashree Rambabu, Brandon G Smith, Stasa Tumpa, Katharina Kohler, Angelos G Kolias, Peter J Hutchinson, Tom Bashford
Papilledema is a pathology delineated by the swelling of the optic disc secondary to raised intracranial pressure (ICP). Diagnosis by ophthalmoscopy can be useful in the timely stratification of further investigations, such as magnetic resonance imaging or computed tomography to rule out pathologies associated with raised ICP. In resource-limited settings, in particular, access to trained specialists or radiological imaging may not always be readily available, and accurate fundoscopy-based identification of papilledema could be a useful tool for triage and escalation to tertiary care centres...
March 2024: International journal of surgery protocols
https://read.qxmd.com/read/38430420/prognostic-impact-of-clinical-and-radiological-factors-on-leptomeningeal-metastasis-from-solid-cancers
#16
JOURNAL ARTICLE
Kanji Nakagawa, Koji Takano, Kazumi Nishino, Shuichi Ohe, Takahiro Nakayama, Hideyuki Arita
PURPOSE: The number of leptomeningeal metastasis (LM) patients has increased in recent years, as the cancer survival rates increased. An optimal prediction of prognosis is essential for selecting an appropriate treatment. The European Association of Neuro-Oncology-European Society for Medical Oncology (EANO-ESMO) guidelines for LM proposed a classification based on the cerebrospinal fluid cytological findings and contrast-enhanced magnetic resonance imaging (MRI) pattern. However, few studies have validated the utility of this classification...
March 2, 2024: Journal of Neuro-oncology
https://read.qxmd.com/read/38428951/does-spinal-cord-type-predict-intraoperative-neuro-monitoring-alerts-in-scoliosis-correction-surgery-a-systematic-review-and-meta-analysis-of-operative-and-radiologic-predictors
#17
REVIEW
Abdulrahman O Al-Naseem, Abdulaziz O Al-Naseem, Derek T Cawley, Ahmed Aoude, Anthony A Catanzano, Muhammad M Abd-El-Barr, Aman Sharma, Roozbeh Shafafy
STUDY DESIGN: Systematic literature review and meta-analysis. OBJECTIVES: Predicting patient risk of intraoperative neuromonitoring (IONM) alerts preoperatively can aid patient counselling and surgical planning. Sielatycki et al established an axial-MRI-based spinal cord classification system to predict risk of IONM alerts in scoliosis correction surgery. We aim to systematically review the literature on operative and radiologic factors associated with IONM alerts, including a novel spinal cord classification...
March 1, 2024: Global Spine Journal
https://read.qxmd.com/read/38427131/virtual-multi-institutional-tumor-board-a-strategy-for-personalized-diagnoses-and-management-of-rare-cns-tumors
#18
JOURNAL ARTICLE
James L Rogers, Thomas Wall, Alvina A Acquaye-Mallory, Lisa Boris, Yeonju Kim, Kenneth Aldape, Martha M Quezado, John A Butman, James G Smirniotopoulos, Huma Chaudhry, Christina I Tsien, Prashant Chittiboina, Kareem Zaghloul, Orwa Aboud, Nicholas G Avgeropoulos, Eric C Burton, David M Cachia, Karan S Dixit, Jan Drappatz, Erin M Dunbar, Peter Forsyth, Edina Komlodi-Pasztor, Jacob Mandel, Byram H Ozer, Eudocia Q Lee, Surabhi Ranjan, Rimas V Lukas, Margarita Raygada, Michael E Salacz, Matthew A Smith-Cohn, James Snyder, Ariane Soldatos, Brett J Theeler, Brigitte C Widemann, Kevin A Camphausen, John D Heiss, Terri S Armstrong, Mark R Gilbert, Marta Penas-Prado
PURPOSE: Multidisciplinary tumor boards (MTBs) integrate clinical, molecular, and radiological information and facilitate coordination of neuro-oncology care. During the COVID-19 pandemic, our MTB transitioned to a virtual and multi-institutional format. We hypothesized that this expansion would allow expert review of challenging neuro-oncology cases and contribute to the care of patients with limited access to specialized centers. METHODS: We retrospectively reviewed records from virtual MTBs held between 04/2020-03/2021...
March 1, 2024: Journal of Neuro-oncology
https://read.qxmd.com/read/38423768/prospective-study-examining-the-impact-of-cerebral-angiography-on-quantitative-pupillometer-values-in-the-interventional-radiology-suite
#19
JOURNAL ARTICLE
Brian Nguyen, Jade L Marshall, Chahat Rana, Folefac D Atem, Sonja E Stutzman, DaiWai M Olson, Venkatesh Aiyagari, Bappaditya Ray
OBJECTIVES: The purpose of this pilot study was to obtain baseline quantitative pupillometry (QP) measurements before and after catheter-directed cerebral angiography (DCA) to explore the hypothesis that cerebral angiography is an independent predictor of change in pupillary light reflex (PLR) metrics. DESIGN: This was a prospective, observational pilot study of PLR assessments obtained using QP 30 min before and after DCA. All patients had QP measurements performed with the NPi-300 (Neuroptics) pupillometer...
February 29, 2024: BMJ Open
https://read.qxmd.com/read/38421185/comprehensive-and-integrated-management-of-basilar-impression-platybasia-and-cranio-vertebral-junction-abnormality-a-case-report
#20
JOURNAL ARTICLE
Nikhil Pantbalekundri, Anjalee Chiwane, Harshita Reddy, Manjit Kothari
Platybasia is a developmental defect of the occipital bone and upper cervical spine resulting from anomalous development. The mechanism of such anomaly is not known however the most accepted theory includes abnormal basi-occiput development. It tends to produce marked pressure effects on the brain stem and cervical vertebrae. These pressure effects may present as signs similar to progressive spastic paralysis, cerebellar symptoms or cranial nerve palsy besides musculoskeletal symptoms. It is, therefore, crucial for physicians and radiologists to be familiar with clinical manifestations and radiological findings...
February 29, 2024: International Journal of Neuroscience
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