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https://www.readbyqxmd.com/read/29454351/disparate-compensation-policies-for-research-related-injury-in-an-era-of-multinational-trials-a-case-study-of-brazil-russia-india-china-and-south-africa
#1
George Rugare Chingarande, Keymanthri Moodley
BACKGROUND: Compensation for research related injuries is a subject that is increasingly gaining traction in developing countries which are burgeoning destinations of multi center research. However, the existence of disparate compensation rules violates the ethical principle of fairness. The current paper presents a comparison of the policies of Brazil, Russia, India, China and South Africa (BRICS). METHODS: A systematic search of good clinical practice guidelines was conducted employing search strategies modeled in line with the recommendations of ADPTE Collaboration (2007)...
February 17, 2018: BMC Medical Ethics
https://www.readbyqxmd.com/read/29452550/an-eye-on-vision-20-questions-about-vision-screening-and-eye-health
#2
P Kay Nottingham Chaplin, Kira Baldonado, Geoffrey E Bradford, Susan Cotter, Bruce Moore
Current evidence-based and best practice vision screening and eye health approaches, tools, and procedures are the result of revised national guidelines in the past 3 years and advances in research during the last 16 years. To help the busy school nurse with little time to keep up with changes in children's vision practices and a growing body of literature, the National Center for Children's Vision and Eye Health at Prevent Blindness is providing answers to 20 questions received most often from the field. Question topics are: (1) arranging the screening environment, (2) occluders to cover the eyes during vision screening, (3) optotype-based screening at distance, (4) optotype-based screening at near, (5) instrument-based screening, (6) muscle imbalance screening, (7) referrals, and (8) vision screening certification...
March 2018: NASN School Nurse
https://www.readbyqxmd.com/read/29452361/iui-review-and-systematic-assessment-of-the-evidence-that-supports-global-recommendations
#3
Ben Cohlen, Aartjan Bijkerk, Sheryl Van der Poel, Willem Ombelet
BACKGROUND: IUI with or without ovarian stimulation (OS) has become a first-line treatment option for many infertile couples, worldwide. The appropriate treatment modality for couples and their clinical management through IUI or IUI/OS cycles must consider maternal and perinatal outcomes, most notably the clinical complication of higher-order multiple pregnancies associated with IUI-OS. With a current global emphasis to continue to decrease maternal and perinatal mortality and morbidity, the World Health Organization (WHO) had established a multi-year project to review the evidence for the establishment of normative guidance for the implementation of IUI as a treatment to address fertility problems, and to consider its cost-effectiveness for lower resource settings...
February 14, 2018: Human Reproduction Update
https://www.readbyqxmd.com/read/29451509/-diagnosis-and-treatment-of-blood-volume-changes-in-acute-heart-failure-a-brief-practical-guide
#4
Paola Ciancetta, Salvatore M Maggiore, Flavia Petrini, Raffaele De Caterina
The correct management of acute heart failure continues to pose diagnostic and therapeutic challenges. In particular, administering the right type and dose of fluids and drugs, thus avoiding fluid overload while establishing organ perfusion, is of key importance in stabilizing critical patients and improving prognosis. A correct estimate of the fluid volume status, however, may be difficult, as the invasive evaluation of cardiac filling pressures by cardiac catheterization is limited in routine medical practice, and there is no universal consensus on the best tools for its non-invasive evaluation...
January 2018: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29449241/simplified-guideline-for-prescribing-medical-cannabinoids-in-primary-care
#5
G Michael Allan, Jamil Ramji, Danielle Perry, Joey Ton, Nathan P Beahm, Nicole Crisp, Beverly Dockrill, Ruth E Dubin, Ted Findlay, Jessica Kirkwood, Michael Fleming, Ken Makus, Xiaofu Zhu, Christina Korownyk, Michael R Kolber, James McCormack, Sharon Nickel, Guillermina Noël, Adrienne J Lindblad
OBJECTIVE: To develop a clinical practice guideline for a simplified approach to medical cannabinoid use in primary care; the focus was on primary care application, with a strong emphasis on best available evidence and a promotion of shared, informed decision making. METHODS: The Evidence Review Group performed a detailed systematic review of 4 clinical areas with the best evidence around cannabinoids: pain, nausea and vomiting, spasticity, and adverse events. Nine health professionals (2 generalist family physicians, 2 pain management-focused family physicians, 1 inner-city family physician, 1 neurologist, 1 oncologist, 1 nurse practitioner, and 1 pharmacist) and a patient representative comprised the Prescribing Guideline Committee (PGC), along with 2 nonvoting members (pharmacist project managers)...
February 2018: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29447403/assessment-of-data-quality-and-reporting-systems-for-underserved-populations-the-case-of-integrated-community-case-management-programs-in-nigeria
#6
Florence M Nyangara, Tajrina Hai, Kirsten Zalisk, Lynda Ozor, Joy Ufere, Chinwoke Isiguzo, Ibrahim Ndaliman Abubakar
Decision makers are searching for reliable data and best practices to support the implementation and scale-up of the integrated community case management (iCCM) programs in underserved areas to reduce under-five mortality in low-income countries. This study assesses data quality and reporting systems of the World Health Organization supported Rapid Access Expansion program implementing iCCM in Abia and Niger States, Nigeria. This cross-sectional study used data from 16 primary health facilities in both states...
February 13, 2018: Health Policy and Planning
https://www.readbyqxmd.com/read/29447370/management-of-gout-by-uk-rheumatologists-a-british-society-for-rheumatology-national-audit
#7
Edward Roddy, Jon Packham, Karen Obrenovic, Ali Rivett, Joanna M Ledingham
Objectives: To assess the concordance of gout management by UK rheumatologists with evidence-based best-practice recommendations. Methods: Data were collected on patients newly referred to UK rheumatology out-patient departments over an 8-week period. Baseline data included demographics, method of diagnosis, clinical features, comorbidities, urate-lowering therapy (ULT), prophylaxis and blood tests. Twelve months later, the most recent serum uric acid level was collected...
February 13, 2018: Rheumatology
https://www.readbyqxmd.com/read/29447071/a-social-media-intervention-to-improve-hypoglycaemia-management-at-a-multi-centre-hospital-a-quality-improvement-pilot-for-clinical-nurses
#8
Filomena De Sousa, Jennifer Jackson, Ruth Knight, Edith Cloutier, Rosemary Basa, Anne Fourney, Kathleen Devecseri
BACKGROUND: Hypoglycaemia is associated with increased mortality, length of stay, readmission and adverse events. Nursing management of hypoglycaemia is a challenge, despite established best practice guidelines. Social media is an effective tool for sharing information, and had potential to overcome barriers to clinical education at a multi-centre hospital. AIMS: The purpose of this quality improvement intervention was to create and disseminate social media posts about best practices in hypoglycaemia management...
February 15, 2018: Contemporary Nurse
https://www.readbyqxmd.com/read/29446071/indistinguishability-tests-in-the-actor-partner-interdependence-model
#9
Fien Gistelinck, Tom Loeys, Mieke Decuyper, Marieke Dewitte
When considering dyadic data, one of the questions is whether the roles of the two dyad members can be considered equal. This question may be answered empirically using indistinguishability tests in the actor-partner interdependence model. In this paper several issues related to such indistinguishability tests are discussed: the difference between maximum likelihood and restricted maximum likelihood based tests for equality in variance parameters; the choice between the structural equation modelling and multilevel modelling framework; and the use of sequential testing rather than one global test for a set of indistinguishability tests...
February 15, 2018: British Journal of Mathematical and Statistical Psychology
https://www.readbyqxmd.com/read/29444992/microbiological-control-for-affinity-capture-chromatography-processing-an-industry-perspective
#10
Marie Murphy, Brian Bell, James Moshi, Robert Grassi, Ren-Yo Forng, Angel Salaman, Petra Wawra Jordi, Simin Zaidi, Marcella Goodnight, Kim McFarland, Diane Hardy, Michael Knight, Mousumi Paul, Andreas Keller, Bill Carpenter, Donal McLaughlin, Una Hearty, Jose Marrero, David Bain, Derek Willison-Parry
The purpose of this paper is to provide a summary of a BPOG-led industry survey of the microbiological control aspects of affinity chromatography processing in the biopharmaceutical industry. The document provides a summary of historical microbiological control concerns, coupled with industry-derived best practices for material, equipment, and storage controls required to mitigate the potential for microbial ingress and contamination of chromatography resin and equipment. These best practice guidelines, which are derived from the members of the BPOG Bioburden Working Group, are intended to assist biopharmaceutical manufacturers enhance microbial control and monitoring strategies for chromatography systems...
February 14, 2018: PDA Journal of Pharmaceutical Science and Technology
https://www.readbyqxmd.com/read/29441604/national-survey-of-patch-testing-in-the-united-kingdom-and-republic-of-ireland-what-proportion-of-the-population-is-and-should-be-tested
#11
Bevin Bhoyrul, Samantha Keegan, Avad Mughal
BACKGROUND: An initial study of patch testing practices across Wales, United Kingdom, showed wide variation in practice against a standardized set of guidelines and best practice recommendations. OBJECTIVES: To evaluate (i) current patch testing practice on a national level in the United Kingdom and Republic of Ireland (ROI), (ii) compliance with the current published guidelines, and (iii) the proportion of the catchment population tested by patch testing centres...
February 14, 2018: Contact Dermatitis
https://www.readbyqxmd.com/read/29439286/evidence-flowers-an-innovative-visual-method-of-presenting-best-evidence-summaries-to-health-professional-and-lay-audiences
#12
O O Babatunde, V Tan, J L Jordan, K Dziedzic, C A Chew-Graham, C Jinks, J Protheroe, D A van der Windt
BACKGROUND & AIMS: Barriers to dissemination and engagement with evidence pose a threat to implementing evidence-based medicine. Understanding, retention and recall can be enhanced by visual presentation of information. The aim of this exploratory research was to develop and evaluate the accessibility and acceptability of visual summaries for presenting evidence syntheses with multiple exposures or outcomes to professional and lay audiences. METHODS: 'Evidence flowers' were developed as a visual method of presenting data from four case scenarios: two complex evidence syntheses with multiple outcomes, Cochrane reviews and clinical guidelines...
February 13, 2018: Research Synthesis Methods
https://www.readbyqxmd.com/read/29437084/increasing-adherence-to-brain-trauma-foundation-guidelines-for-hospital-care-of-patients-with-traumatic-brain-injury
#13
Ali A Saherwala, Mary Kay Bader, Sonja E Stutzman, Stephen A Figueroa, Jamshid Ghajar, April R Gorman, Abu Minhajuddin, DaiWai M Olson
BACKGROUND: The Brain Trauma Foundation has developed treatment guidelines for the care of patients with acute traumatic brain injury. The Adam Williams Initiative is a program established to provide education and resources to encourage hospitals across the United States to incorporate the guidelines into practice. OBJECTIVE: To explore the relationship in hospitals between participation in the Adam Williams Initiative and adherence to the Brain Trauma Foundation guidelines for patients with acute traumatic brain injury...
February 2018: Critical Care Nurse
https://www.readbyqxmd.com/read/29436699/-bipolar-disorder-and-alcohol-use-disorder-practical-recommendations-for-treatment-based-on-a-literature-review
#14
A T Spijker, J van Zaane, M A Koenders, R Hoekstra, R W Kupka
A fairly large proportion (25-50%) of patients with bipolar disorder (bd) also suffer from comorbid alcohol use disorder (aud). However, little is known how this type of morbidity should be treated. It is also unclear whether the current guidelines on bd have been influenced by aud.<br/> AIM: To provide an overview of recent literature concerning the diagnosis and treatment of comorbid bd and aud.<br/> METHOD: We systematically reviewed studies that have addressed three treatment options for this group of patients: pharmaco-therapy, psychological interventions and self-management techniques...
2018: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/29432601/surf-copd-the-recording-of-cardiovascular-risk-in-patients-with-chronic-lung-disease
#15
A Dudina, S Lane, M Butler, M-T Cooney, I Graham
Background: Cardiovascular disease (CVD) is the leading cause of death in patients with chronic obstructive pulmonary disease (COPD) and such patients tend to carry a heavy burden of risk factors for CVD. There is little information on the documentation and management of CVD risk factors in COPD patients. Aim: To audit the recording and management of CVD risk factors in 200 COPD patients attending the respiratory out-patient clinics at two University teaching hospitals...
February 8, 2018: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29427992/apple-condom-and-cocaine-body-stuffing-in-prison-a-case-report
#16
Benedicte Jalbert, Nguyen Toan Tran, Stephan von Düring, Pierre-Alexandre Poletti, Ian Fournier, Catherine Hafner, Celestine Dubost, Laurent Gétaz, Hans Wolff
BACKGROUND: Drug dealers and drug users resort to body stuffing to hastily conceal illicit drugs by ingesting their drug packets. This practice represents a medical challenge because rupture of the often insecure packaging can be toxic and even lethal. In an emergency setting, official guidelines are needed to help the medical team decide on the proper treatment. A preliminary observation period is generally accepted but its duration varies from hours to eventual packet expulsion. CASE PRESENTATION: This case involves a 20-year-old white man in detention who claimed to have ingested one cocaine packet wrapped in plastic food-wrap and a condom in anticipation of an impending cell search...
February 11, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29427494/diagnosis-of-non-alcoholic-fatty-liver-disease-non-alcoholic-steatohepatitis-non-invasive-tests-are-enough
#17
REVIEW
Laurent Castera
Non-alcoholic fatty liver disease is a major cause of liver disease worldwide and the most common liver disorder in Western countries, affecting around 25% of the general population. Fibrosis is the major long-term histological prognostic criteria of this disease. Liver biopsy cannot be realistically performed in such a huge population and, moreover, has well-known limitations (invasiveness, rare but potentially life-threatening complications and sampling variability). Over the past decade, there has been a growing interest in alternative novel strategies for the non-invasive evaluation of fibrosis...
February 2018: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29422373/international-commission-for-mountain-emergency-medicine-consensus-guidelines-for-on-site-management-and-transport-of-patients-in-canyoning-incidents
#18
REVIEW
Giacomo Strapazzon, Oliver Reisten, Fabien Argenone, Ken Zafren, Greg Zen-Ruffinen, Gordon L Larsen, Inigo Soteras
Canyoning is a recreational activity that has increased in popularity in the last decade in Europe and North America, resulting in up to 40% of the total search and rescue costs in some geographic locations. The International Commission for Mountain Emergency Medicine convened an expert panel to develop recommendations for on-site management and transport of patients in canyoning incidents. The goal of the current review is to provide guidance to healthcare providers and canyoning rescue professionals about best practices for rescue and medical treatment through the evaluation of the existing best evidence, focusing on the unique combination of remoteness, water exposure, limited on-site patient management options, and technically challenging terrain...
February 5, 2018: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/29422252/achieving-high-quality-standards-in-laparoscopic-colon-resection-for-cancer-a-delphi-consensus-based-position-paper
#19
Laura Lorenzon, Alberto Biondi, Thomas Carus, Adam Dziki, Eloy Espin, Nuno Figueiredo, Marcos Gomez Ruiz, Tamas Mersich, Isacco Montroni, Pieter J Tanis, Stefan Rolf Benz, Paolo Pietro Bianchi, Matthias Biebl, Ivo Broeders, Raffaele De Luca, Paolo Delrio, Mathieu D'Hondt, Alois Fürst, Jan Grosek, Jose Flavio Guimaraes Videira, Friedrich Herbst, David Jayne, György Lázár, Danilo Miskovic, Andrea Muratore, Ole Helmer Sjo, Tom Scheinin, Ales Tomazic, Andreas Türler, Cornelius Van de Velde, Steven D Wexner, Christoph Wullstein, Wojciech Zegarski, Domenico D'Ugo
AIM: To investigate the rate of laparoscopic colectomies for colon cancer using registries and population-based studies. To provide a position paper on mini-invasive (MIS) colon cancer surgery based on the opinion of experts leader in this field. METHODS: A systematic review of the literature was conducted using PRISMA guidelines for the rate of laparoscopy in colon cancer. Moreover, Delphi methodology was used to reach consensus among 35 international experts in four study rounds...
February 5, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29421949/sperm-toxicity-testing-uk-best-practice-guideline-from-the-association-of-biomedical-andrologists
#20
S Long, B Woodward, M Tomlinson
In order to ensure the quality and integrity of diagnostic semen analysis results, materials used should be tested to ensure that they do not interfere with sperm function. As a toxicity test, complex sperm function testing may be considered controversial, since the fertilizing capacity of single sperm can never be assured. In preference, sperm motility offers a unique means of assessing the toxicity of reagents and materials before they are used in routine practice. Motility is the semen parameter most likely to be influenced by the external environment...
February 9, 2018: British Journal of Biomedical Science
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