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https://www.readbyqxmd.com/read/29929117/psychiatric-comorbidity-increases-mortality-in-immune-mediated-inflammatory-diseases
#1
Ruth Ann Marrie, Randy Walld, James M Bolton, Jitender Sareen, Scott B Patten, Alexander Singer, Lisa M Lix, Carol A Hitchon, Renée El-Gabalawy, Alan Katz, John D Fisk, Charles N Bernstein
OBJECTIVE: We determined the association between any common mental disorder (CMD: depression, anxiety disorder, bipolar disorder) and mortality and suicide in three immune-mediated inflammatory diseases (IMID), inflammatory bowel disease (IBD), multiple sclerosis (MS) and rheumatoid arthritis (RA), versus age-, sex- and geographically-matched controls. METHODS: Using administrative data, we identified 28,384 IMID cases (IBD: 8695; MS: 5496; RA: 14,503) and 141,672 matched controls...
June 7, 2018: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29928864/definition-development-and-prevalence-of-new-persistent-opioid-use-following-hysterectomy
#2
Carolyn W Swenson, Neil S Kamdar, Kristian Seiler, Daniel M Morgan, Paul Lin, Sawsan As-Sanie
BACKGROUND: Opioids used for postoperative pain control after surgery have been associated with an increased risk of chronic opioid use. Hysterectomy is the most common major gynecologic procedure in the United States; however, we lack a data-driven definition of new persistent opioid use specific to hysterectomy. OBJECTIVE: 1) Determine a data-driven definition of new persistent opioid use among opioid naïve women undergoing hysterectomy; 2) Determine the prevalence of and risk factors for new persistent opioid use...
June 18, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29928823/weaning-and-mixed-mania-a-case-report
#3
Verinder Sharma
INTRODUCTION: The development of mania during weaning is an underreported phenomenon that has received little attention in the recent past. Lack of timely diagnosis and effective management can negatively affect not only the mother but also her family. Main issue: I describe the case of a woman who experienced onset of mixed mania during weaning. At that time, she was diagnosed with bipolar I disorder, current episode manic, and a mixed-features specifier. The woman had a history of bipolar II disorder and a family history of postpartum depression and bipolar disorder...
June 1, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/29928593/diminished-hedonic-response-in-neuroleptic-free-youth-at-ultra-high-risk-for-psychosis
#4
Gregory P Strauss, Ivan Ruiz, Katherine H Visser, Laura P Crespo, Elizabeth K Dickinson
Hedonic response is preserved in schizophrenia. However, it is unclear whether this is also true in individuals meeting criteria for "prodromal" psychosis, who are considered to be at symptomatic high risk for developing the disorder. In this study, we examined neurophysiological and self-reported response to emotional stimuli in UHR ( n  = 23) and healthy control (CN: n  = 30) participants who passively viewed pleasant, unpleasant, and neutral images for 500 ms while the electroencephalogram was recorded and then provided self-reports of valence and arousal to the stimuli...
June 2018: Schizophrenia Research. Cognition
https://www.readbyqxmd.com/read/29928468/tolerability-and-safety-profile-of-a-new-brand-generic-product-of-glatiramer-acetate-in-iranian-patients-with-relapsing-remitting-multiple-sclerosis-an-observational-cohort-study
#5
Roya Abolfazli, Shirin Pournourmohammadi, Ahmadreza Shamshiri, Sara Samadzadeh
Background: The aim of this study was to evaluate the safety, tolerability, and efficacy of a brand-generic glatiramer acetate product in patients with relapsing-remitting multiple sclerosis over a 12-month period. A noninterventional cohort study was conducted on 185 patients. The patients had a confirmed and documented diagnosis of relapsing-remitting multiple sclerosis as defined by the Revised McDonald Criteria (2010), were ambulatory with a Kurtzke Expanded Disability Status Scale score of 0 to 5...
2018: Current Therapeutic Research, Clinical and Experimental
https://www.readbyqxmd.com/read/29928292/a-patient-perspective-on-recurrent-or-prolonged-contact-with-psychiatric-inpatient-care-for-affective-disorder
#6
Emil Brännström, Jennifer Strand, Peter Sand
Background: The aim of this qualitative study was to explore why some patients receive recurrent or prolonged psychiatric inpatient care, based on the experiences of the patients themselves. Methods: The participants were recruited at an outpatient clinic at the department of psychiatry for patients with affective disorders at Sahlgrenska University Hospital, Sweden. Ten patients, nine women and one man, aged 22-61 years, agreed to participate. A semi-structured interview guide was used during the interviews, which were audiotaped, transcribed, and analyzed using interpretative phenomenological analysis...
2018: International Journal of Mental Health Systems
https://www.readbyqxmd.com/read/29928190/mitochondria-and-mood-mitochondrial-dysfunction-as-a-key-player-in-the-manifestation-of-depression
#7
REVIEW
Josh Allen, Raquel Romay-Tallon, Kyle J Brymer, Hector J Caruncho, Lisa E Kalynchuk
Human and animal studies suggest an intriguing link between mitochondrial diseases and depression. Although depression has historically been linked to alterations in monoaminergic pharmacology and adult hippocampal neurogenesis, new data increasingly implicate broader forms of dampened plasticity, including plasticity within the cell. Mitochondria are the cellular powerhouse of eukaryotic cells, and they also regulate brain function through oxidative stress and apoptosis. In this paper, we make the case that mitochondrial dysfunction could play an important role in the pathophysiology of depression...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29928123/addictive-potential-of-novel-treatments-for-refractory-depression-and-anxiety
#8
REVIEW
Dusan Kolar
Treatment-resistant mood disorders and anxiety disorders require intensive treatment, but treatment options should balance benefits and adverse effects or other potential detrimental effects on patients, including the risk of developing prescription medication addiction. Some of the newer treatment modalities for mood and anxiety disorders may have similar properties to benzodiazepines. The goal of this review was to identify the potential for developing dependence on the novel treatment approaches to treatment-resistant depression and refractory anxiety disorders...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29928121/electroencephalogram-alpha-asymmetry-in-patients-with-depressive-disorders-current-perspectives
#9
REVIEW
Andreas Kurt Kaiser, Maria-Theresa Gnjezda, Stephanie Knasmüller, Wolfgang Aichhorn
Purpose: Electroencephalogram (EEG) alpha asymmetry (AA) in depressive disorders has been of interest over the last few decades, but it continues to remain unclear whether EEG AA can discriminate between healthy and depressive individuals. Materials and methods: A systematic literature search for papers addressing EEG AA using the keywords alpha asymmetry, depression, and EEG was performed in PubMed. All studies were checked for sample size, gender, handedness, reference, recording protocol, EEG band range, impedance, type of analysis, drugs, and comorbidity...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29927960/occupational-exposure-factors-for-mental-and-behavioral-disorders-at-work-the-forec-thesaurus
#10
Alain Chamoux, Céline Lambert, Audrey Vilmant, Charlotte Lanhers, Raymond Agius, Mounir Boutaleb, Vincent Bonneterre, Geraldine Naughton, Bruno Pereira, Khalid Djeriri, Eric Ben-Brik, Christine Breton, Caroline De Clavière, Corinne Letheux, Anne-Gaëlle Paolillo, Madeleine Valenty, Odile Vandenberghe, Marie-Pierre Aeschlimann, Gérard Lasfargues, Francois-Xavier Lesage, Frédéric Dutheil
BACKGROUND: Mental disorders in the workplace are a major public health problem. Knowledge of the impact of the psychosocial work environment on mental and behavioral disorders can assist occupational physicians in the identification and description of occupational risk situations, and help to define priority actions. However, no classification for occupational exposure factors is currently available. We aimed to build a thesaurus of "Organizational, Relational, Ethical and other Contributing Factors" (FOREC) linked with the onset of mental and behavioral disorders...
2018: PloS One
https://www.readbyqxmd.com/read/29927937/binge-eating-trauma-and-suicide-attempt-in-community-adults-with-major-depressive-disorder
#11
Ji Hyun Baek, Kiwon Kim, Jin Pyo Hong, Maeng Je Cho, Maurizio Fava, David Mischoulon, Sung Man Chang, Ji Yeon Kim, Hana Cho, Hong Jin Jeon
Eating disorders comorbid with depression are an established risk factor for suicide. In this study, we aimed to determine the effects of binge eating (BE) symptoms on suicidality and related clinical characteristics in major depressive disorder (MDD). A total of 817 community participants with MDD were included. We compared two groups (with and without lifetime BE symptoms). The MDD with BE group was subdivided into a frequent BE (FBE) subgroup (BE symptoms greater than twice weekly) and any BE (ABE) subgroup (BE symptoms greater than twice weekly)...
2018: PloS One
https://www.readbyqxmd.com/read/29927803/postural-disorders-and-antiparkinsonian-treatments-in-parkinson-disease-an-exploratory-case-control-study
#12
Lucía Ameghino, Verónica Bruno, Marcelo Merello
OBJECTIVE: The aim of this study was to evaluate the relationship between antiparkinsonian treatments, especially dopamine agonist (DAs) and the development of postural disorders in patients with Parkinson's disease (PD). METHODS: We performed an exploratory case-control study. Cases were PD patients with camptocormia, Pisa syndrome, or anterocollis. Control subjects were PD patients without postural disorders matched by sex and age. Demographic and clinical data including pharmacologic treatments history were collected retrospectively...
June 20, 2018: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/29927696/pregnancy-as-a-window-to-racial-disparities-in-hypertension
#13
Claire E Margerison, Janet Catov, Claudia Holzman
BACKGROUND: The black-white disparity in hypertension (HTN) among U.S. women persists after accounting for known risk factors. Pregnancy complications may reveal increased risks for later HTN. We examined the contribution of HTN risk factors measured at both midlife and pregnancy to black-white disparities in midlife HTN. METHODS: Data came from a Michigan-based longitudinal study beginning in pregnancy. At 7-15 years postpregnancy (n = 615, mean age = 37), women were assessed for cardiovascular health, including blood pressure, and categorized as hypertensive (n = 126), prehypertensive (n = 149), and normotensive (n = 340)...
June 21, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29927417/-a-role-of-progesterone-and-its-metabolites-in-regulation-functions-of-the-brain
#14
G P Ivanova, L N Gorobets, A V Litvinov, V S Bulanov, L M Vasilenko
The review presents literature data reflecting the nature and mechanism of the effect of progesterone and its metabolites on human and animal brain structures. Particular attention is paid to neuroprotective, anticonvulsant, anti-anxiety and sedative properties of this hormone, which determines the prospect of its use for the prevention and treatment of human neurodegenerative diseases, epilepsy, sleep disorders, and anxiety-depressive spectrum disorders, including premenstrual and climacteric syndromes.
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29927272/condom-use-self-efficacy-as-a-mediator-between-syndemics-and-condomless-sex-in-men-who-have-sex-with-men-msm
#15
Steven A Safren, Aaron J Blashill, Jasper S Lee, Conall O'Cleirigh, Julia Tomassili, Katie B Biello, Matthew J Mimiaga, Kenneth H Mayer
OBJECTIVE: Among men who have sex with men (MSM), HIV sexual risk and poor self-care behavior is associated with syndemics, or co-occurring psychosocial problems. Though prior research has demonstrated an additive total effect of syndemics on HIV risk behavior and infection, mostly within cross-sectional designs, it is possible that these associations are not direct but rather that syndemics disrupt relevant individual-level mediating psychological variables. One of the more common individual-level psychological variables that predicts health behavior generally, and HIV risk behavior specifically, is self-efficacy...
June 21, 2018: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/29927088/diversity-of-neurodegenerative-pathophysiology-in-nondemented-patients-with-major-depressive-disorder-evidence-of-cerebral-amyloidosis-and-hippocampal-atrophy
#16
Kuan-Yi Wu, Kun-Ju Lin, Chia-Hsiang Chen, Cheng-Sheng Chen, Chia-Yih Liu, Sheng-Yao Huang, Tzu-Chen Yen, Ing-Tsung Hsiao
BACKGROUND: Patients with late-life depression may be at the preclinical stage of dementia. However, the neurodegenerative processes in late-life depression are poorly understood. This study aimed to investigate the distribution patterns of amyloid pathology and neurodegeneration in a depressive population without dementia. METHODS: The study recruited 63 middle-aged and elderly patients with major depressive disorder (MDD) and 22 control subjects. The MDD patients were further subdivided into those with mild cognitive impairment (MCI) (n = 24) and non-MCI (n = 39) patients...
June 21, 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29927066/cannabis-use-as-a-risk-factor-for-psychotic-like-experiences-a-systematic-review-of-non-clinical-populations-evaluated-with-the-community-assessment-of-psychic-experiences
#17
REVIEW
Taciana C C Ragazzi, Rosana Shuhama, Paulo R Menezes, Cristina M Del-Ben
AIM: Epidemiological data have provided evidence that psychotic-like experiences (PLEs) can occur in the general population, not necessarily accompanied by the impairment and suffering observed in formal psychiatric diagnoses. According to the psychosis continuum hypothesis, PLEs would be subject to the same risk factors as frank psychosis. The aim of this review was to summarize observational studies that evaluated cannabis use as a risk factor for PLEs as determined by the Community Assessment of Psychic Experiences in non-clinical samples...
June 21, 2018: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29926933/relative-importance-of-posttraumatic-stress-disorder-and-depression-in-predicting-risk-of-suicide-among-a-cohort-of-vietnam-veterans
#18
Tim Bullman, Aaron Schneiderman, Jaimie L Gradus
OBJECTIVE: Research has demonstrated that posttraumatic stress disorder (PTSD) among Vietnam veterans is associated with increased risk of suicide. It is also widely reported that suicide is related to depression. This study examined the effect of PTSD and depression on risk of suicide among a cohort of Vietnam veterans. METHOD: All study subjects were selected from the Department of Veterans Affairs Agent Orange Registry. Suicide risk associated with PTSD was first assessed by comparing the number of suicides among a cohort of 2,874 veterans with PTSD to that of 8,537 veterans not diagnosed with PTSD...
June 21, 2018: Suicide & Life-threatening Behavior
https://www.readbyqxmd.com/read/29926533/incidence-and-characteristics-of-the-nocebo-response-from-meta-analyses-of-the-placebo-arms-of-clinical-trials-of-olanzapine-for-bipolar-disorder
#19
Seetal Dodd, Adam J Walker, Alan J M Brnabic, Nancy Hong, Amber Burns, Michael Berk
OBJECTIVES: In the clinical setting, the nocebo phenomenon is where clinical worsening or adverse events occur as a response to a treatment, in a situation in which conditioning from previous treatment exposure and/or expectations of sickness or symptoms lead to sickness and symptoms in a conditioned or expectant individual. The nocebo response may thus be a confounder in clinical treatment and clinical research. There is a need to know how to predict if an individual is likely to be a nocebo responder, and how significant and commonplace the nocebo effect might be...
June 21, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29926532/multigenerational-transmission-of-liability-to-psychiatric-illness-in-offspring-of-parents-with-bipolar-disorder
#20
Robert M Post, Lori L Altshuler, Ralph Kupka, Susan L McElroy, Mark A Frye, Michael Rowe, Heinz Grunze, Trisha Suppes, Paul E Keck, Gabriele S Leverich, Willem A Nolen
INTRODUCTION: Instead of the typical assessment of risk of illness in the offspring based on a parent with bipolar disorder, we explored the potential multigenerational conveyance across several disorders of the vulnerability to illness in the offspring of a patient with bipolar disorder. METHODS: A total of 968 outpatients (average age 41 years) with bipolar illness gave informed consent and filled out a detailed questionnaire about a family history in their parents, grandparents, and offspring of: depression; bipolar disorder; alcohol abuse; substance abuse; suicide attempt; or "other" illness...
June 21, 2018: Bipolar Disorders
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