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Depressive disorder

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https://www.readbyqxmd.com/read/29053981/clinical-efficacy-onset-time-and-safety-of-bright-light-therapy-in-acute-bipolar-depression-as-an-adjunctive-therapy-a-randomized-controlled-trial
#1
Tian-Hang Zhou, Wei-Min Dang, Yan-Tao Ma, Chang-Qing Hu, Ning Wang, Guo-Yi Zhang, Gang Wang, Chuan Shi, Hua Zhang, Bin Guo, Shu-Zhe Zhou, Lei Feng, Shu-Xia Geng, Yu-Zhen Tong, Guan-Wen Tang, Zhong-Kai He, Long Zhen, Xin Yu
BACKGROUND: Bright light therapy (BLT) is an effective treatment for seasonal affective disorder and non- seasonal depression. The efficacy of BLT in treating patients with bipolar disorder is still unknown. AIMS: The aim of this study is to examine the efficacy, onset time and clinical safety of BLT in treating patients with acute bipolar depression as an adjunctive therapy (trial registration at ClinicalTrials.gov: NCT02009371). METHODS: This was a multi-center, single blind, randomized clinical trial...
September 25, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29053980/incident-mental-disorders-in-the-aftermath-of-traumatic-events-a-prospective-longitudinal-community-study
#2
Eva Asselmann, Hans-Ulrich Wittchen, Roselind Lieb, Axel Perkonigg, Katja Beesdo-Baum
BACKGROUND: Few strictly prospective-longitudinal community studies examined the role of traumatic events for risk of developing a broad range of incident mental disorders over several years. METHOD: A representative community sample of adolescents and young adults (n = 2797, baseline age 14-24) was prospectively examined in up to three assessment waves over up to 10 years. Traumatic events and DSM-IV mental disorders were assessed at each wave using the DIA-X/M-CIDI...
October 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29053976/longitudinal-association-between-mental-disorders-in-childhood-and-subsequent-depression-a-nationwide-prospective-cohort-study
#3
Louise Krarup Gundel, Carsten Bøcker Pedersen, Trine Munk-Olsen, Søren Dalsgaard
BACKGROUND: Depression ranges among the most impairing mental disorders worldwide, and early detection is a global health priority. Little is known about the association between non-affective mental disorders in childhood/adolescence and later depression. METHODS: Nationwide register-based prospective cohort study, estimating cumulative incidences and incidence rate ratios (IRR) for later depression in individuals with and without non-affective mental disorders in early life...
October 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29053849/a-network-meta-analysis-comparing-effects-of-various-antidepressant-classes-on-the-digit-symbol-substitution-test-dsst-as-a-measure-of-cognitive-dysfunction-in-patients-with-major-depressive-disorder
#4
Bernhard T Baune, Mélanie Brignone, Klaus Groes Larsen
Background: Major depressive disorder (MDD) is a common condition that often includes cognitive dysfunction. A systematic literature review of studies and a network meta-analysis (NMA) were carried out to assess the relative effect of antidepressants on cognitive dysfunction in MDD. Methods: MEDLINE ®, Embase ®, Cochrane, CDSR, PsychINFO ® databases, clinical trial registries, and relevant conference abstracts were searched for randomised controlled trials (RCTs) assessing the effects of antidepressants/placebo on cognition...
October 19, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29053820/mood-disorders-and-risk-of-herpes-zoster-in-two-population-based-case-control-studies-in-denmark-and-the-united-kingdom
#5
Sigrun A J Schmidt, Sinéad M Langan, Henrik S Pedersen, Henrik C Schønheyder, Sara L Thomas, Liam Smeeth, Kathryn E Mansfield, Henrik T Sørensen, Harriet J Forbes, Mogens Vestergaard
We examined the association between mood disorders and risk of herpes zoster in two case-control studies using data from nationwide Danish registries and practices in the UK Clinical Practice Research Datalink. We included incident zoster cases diagnosed in general practice (using systemic antivirals as proxy in Denmark) or hospital during 1997-2013 in Denmark (n = 190,671) and during 2000-2013 in the UK (n = 177,361). We risk-set sampled four matched population controls per case. Conditional logistic regression analyses adjusted for zoster risk factors showed that the odds ratios (ORs) for previous mood disorder among cases vs...
October 19, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29053648/influence-of-clinical-and-psychological-variables-upon-the-oral-health-related-quality-of-life-in-patients-with-temporomandibular-disorders
#6
A Blanco-Aguilera, E Blanco-Aguilera, R Serrano-Del-Rosal, L Biedma-Velázquez, A Rodriguez-Torronteras, R Segura-Saint-Gerons, A Blanco-Hungria
BACKGROUND: To analyze the association between the OHIP-14 and the different subtypes making up the clinical and psychological axis obtained using the RDC/TMD. MATERIAL AND METHODS: 407 patients treated at the TMD unit of the Andalusian Healthcare Service were administered the Spanish version of the Research Diagnostic Criteria for Temporomandibular Disorders questionnaire (RDC/TMD), together with the Oral Health Impact Profile questionnaire (OHIP-14). The degree of association between the patients' score in the OHIP-14 and the clinical and biopsychosocial variables was analyzed through bivariate and multivariate analyses, specifically through linear regression...
October 20, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29053637/progress-in-genetic-studies-of-tourette-s-syndrome
#7
REVIEW
Yanjie Qi, Yi Zheng, Zhanjiang Li, Lan Xiong
Tourette's Syndrome (TS) is a complex disorder characterized by repetitive, sudden, and involuntary movements or vocalizations, called tics. Tics usually appear in childhood, and their severity varies over time. In addition to frequent tics, people with TS are at risk for associated problems including attention deficit hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), anxiety, depression, and problems with sleep. TS occurs in most populations and ethnic groups worldwide, and it is more common in males than in females...
October 20, 2017: Brain Sciences
https://www.readbyqxmd.com/read/29053114/-evolution-of-the-schizophrenic-deficit-concept
#8
A B Smulevich, D V Romanov, E I Voronova, A K Mukhorina, V V Chitlova, O Yu Sorokina
The relevance of this study is the high prevalence and clinical heterogeneity of deficit states in chronic schizophrenia and schizophrenia spectrum disorders. The study aimed at analyzing negative symptoms in schizophrenia and schizophrenia spectrum disorders from historical and modern perspectives. An analysis of available literature, along with own observations, has been performed. It was found that negative symptoms comprise 3 clinical types: 1) 'pseudopsychopathic' type (overlapping personality dimensions and premorbid/initial negative symptoms), 2) pseudoorganic/asthenic/pseudobradiphrenic type (pseudoorganic states), developing at different stages of schizophrenia), 3) 'new'-life pseudopsychopathic type (not associated with premorbid personality traits), developing at late stages in schizophrenia...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29053048/neurofibromatosis-type-1-a-neuro-psycho-cutaneous-syndrome
#9
Christopher K H Burris, Michael A Stier, Shahriar Salamat, Shari Thomas, Simone Lauderdale, Meisha L Raven, Maria E Rodriguez, Devasis N Reddy, Heather D Potter, Daniel M Albert
Neurofibromatosis type 1 (NF1) is an inherited disorder often associated with optic nerve gliomas, low-grade brain tumors, and readily visible signs. Though these features are frequently emphasized, the psychosocial and emotional morbidities are often overlooked. We present a patient with depressive disorder resulting in suicide in a patient with NF1.
October 20, 2017: Orbit
https://www.readbyqxmd.com/read/29053023/n-acetylcysteine-for-nonsuicidal-self-injurious-behavior-in-adolescents-an-open-label-pilot-study
#10
Kathryn R Cullen, Bonnie Klimes-Dougan, Melinda Westlund Schreiner, Patricia Carstedt, Nicholas Marka, Katharine Nelson, Michael J Miller, Kristina Reigstad, Ana Westervelt, Meredith Gunlicks-Stoessel, Lynn E Eberly
BACKGROUND: Nonsuicidal self-injury (NSSI) is common in adolescents and young adults, and few evidence-based treatments are available for this significant problem. N-acetylcysteine (NAC) is a widely available nutritional supplement that has been studied in some psychiatric disorders relevant to NSSI including mood and addictive disorders. This pilot study tested the use of NAC as a potential treatment for NSSI in youth. METHODS: Thirty-five female adolescents and young adults with NSSI aged 13-21 years were enrolled in this study that had an open-label, single-arm study design...
October 20, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29052947/exploring-opportunities-to-support-mental-health-care-using-social-media-a-survey-of-social-media-users-with-mental-illness
#11
John A Naslund, Kelly A Aschbrenner, Gregory J McHugo, Jürgen Unützer, Lisa A Marsch, Stephen J Bartels
AIM: Social media holds promise for expanding the reach of mental health services, especially for young people who frequently use these popular platforms. We surveyed social media users who self-identified as having a mental illness to learn about their use of social media for mental health and to identify opportunities to augment existing mental health services. METHODS: We asked 240 Twitter users who self-identified in their profile as having a mental illness to participate in an online survey...
October 20, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29052616/pregenual-anterior-cingulate-dysfunction-associated-with-depression-in-ocd-an-integrated-multimodal-fmri-1-h-mrs-study
#12
Reza Tadayonnejad, Rangaprakash Deshpande, Olusola Ajilore, Teena Moody, Francesca Morfini, Ronald Ly, Joseph O'Neill, Jamie D Feusner
Depression is a commonly-occurring symptom in obsessive-compulsive disorder (OCD), and is associated with worse functional impairment, poorer quality of life, and poorer treatment response. Understanding the underlying neurochemical and connectivity-based brain mechanisms of this important symptom domain in OCD is necessary for development of novel, more globally effective treatments. To investigate biopsychological mechanisms of comorbid depression in OCD, we examined effective connectivity and neurochemical signatures in the pregenual anterior cingulate cortex (pACC), a structure known to be involved in both OCD and depression...
October 20, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29052464/longitudinal-study-of-objective-and-subjective-cognitive-performance-and-psychological-distress-in-oef-oif-veterans-with-and-without-traumatic-brain-injury
#13
Kerry Donnelly, James P Donnelly, Gary C Warner, C James Kittleson, Paul R King
OBJECTIVE: To describe changes in post-deployment objective and subjective cognitive performance in combat Veterans over 18 months, relative to traumatic brain injury (TBI) status and psychological distress. METHOD: This prospective cohort study examined 500 Veterans from Upstate New York at four time points, six months apart. TBI status was determined by a structured clinical interview. Neuropsychological instruments focused on attention, memory, and executive functions...
October 20, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/29052240/testing-predictions-of-the-emotion-regulation-model-of-binge-eating-disorder
#14
Therese E Kenny, Christopher Singleton, Jacqueline C Carter
OBJECTIVE: The emotion regulation (ER) model of binge eating posits that individuals with binge-eating disorder (BED) experience more intense emotions and greater difficulties in ER than individuals without BED, leading them to binge eat as a means of regulating emotions. According to this model, individuals with BED should report greater difficulties in ER than their non-BED counterparts, the severity of these difficulties should be positively associated with BED symptoms, and this association should be stronger when individuals experience persistent negative emotions (i...
October 20, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29052121/co-occurring-posttraumatic-stress-disorder-and-depression-among-young-children
#15
Alison Salloum, Carly Johnco, Kristin M Smyth, Tanya K Murphy, Eric A Storch
The purpose of this study was to examine differences in: (1) mental health emotional and behavioral problems between young children experiencing PTSD with and without MDD; (2) the incidence of caregiver PTSD and MDD between children with PTSD ± MDD; and (3) the number of traumatic events and interpersonal versus non-interpersonal nature of trauma events among children whose parents sought child trauma-focused treatment. Sixty-six caregivers of children aged 3-7 with PTSD completed semi-structured interviews regarding caregiver and child diagnoses, and caregivers completed self-report measures regarding child symptomatology...
October 19, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/29051842/is-there-a-premotor-phase-of-essential-tremor
#16
REVIEW
Abhishek Lenka, Julian Benito-León, Elan D Louis
BACKGROUND: Essential tremor (ET) is the most common tremor disorder. In addition to its hallmark feature, kinetic tremor of the upper limbs, patients may have a number of non-motor symptoms and signs (NMS). Several lines of evidence suggest that ET is a neurodegenerative disorder and certain NMS may antedate the onset of tremor. This article comprehensively reviews the evidence for the existence of a "premotor phase" of ET, and discusses plausible biological explanations and implications...
2017: Tremor and Other Hyperkinetic Movements
https://www.readbyqxmd.com/read/29051549/chronic-antidepressant-potentiates-spontaneous-activity-of-dorsal-raphe-serotonergic-neurons-by-decreasing-gabab-receptor-mediated-inhibition-of-l-type-calcium-channels
#17
Nozomi Asaoka, Naoya Nishitani, Haruko Kinoshita, Hiroyuki Kawai, Norihiro Shibui, Kazuki Nagayasu, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kaneko
Spontaneous activity of serotonergic neurons of the dorsal raphe nucleus (DRN) regulates mood and motivational state. Potentiation of serotonergic function is one of the therapeutic strategies for treatment of various psychiatric disorders, such as major depression, panic disorder and obsessive-compulsive disorder. However, the control mechanisms of the serotonergic firing activity are still unknown. In this study, we examined the control mechanisms for serotonergic spontaneous activity and effects of chronic antidepressant administration on these mechanisms by using modified ex vivo electrophysiological recording methods...
October 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29051523/emotion-regulating-attentional-control-abnormalities-in-major-depressive-disorder-an-event-related-potential-study
#18
Bin Hu, Juan Rao, Xiaowei Li, Tong Cao, Jianxiu Li, Dennis Majoe, Jürg Gutknecht
Major depressive disorders (MDD) exhibit cognitive dysfunction with respect to attention. The deficiencies in cognitive control of emotional information are associated with MDD as compared to healthy controls (HC). However, the brain mechanism underlying emotion that influences the attentional control in MDD necessitates further research. The present study explores the emotion-regulated cognitive competence in MDD at a dynamic attentional stage. Event-Related Potentials (ERPs) were recorded from 35 clinical MDD outpatients and matched HCs by applying a modified affective priming dot-probe paradigm, which consisted of various emotional facial expression pairs...
October 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29051341/indoor-tanning-dependence-in-young-adult-women
#19
Darren Mays, Michael B Atkins, Jaeil Ahn, Kenneth P Tercyak
Background: There is mounting evidence that young people can develop a dependence on indoor tanning, but research on factors associated with indoor tanning dependence remains limited.Methods: This cross-sectional study investigated factors associated with indoor tanning dependence in a community sample of 389 non-Hispanic white young adult women ages 18 to 30 who had indoor tanned ≥1 time in the past year. Participants completed measures of indoor tanning dependence, including the modified CAGE and modified Diagnostic and Statistical Manual for Mental Disorders-IV psychiatric screening assessments, indoor tanning behavior and beliefs, and behavioral and psychiatric comorbidity...
October 19, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/29051175/associations-between-residual-depressive-symptoms-cognition-and-functioning-in-patients-with-euthymic-bipolar-disorder-results-from-the-face-bd-cohort
#20
Paul Roux, Aurélie Raust, Anne-Sophie Cannavo, Valérie Aubin, Bruno Aouizerate, Jean-Michel Azorin, Frank Bellivier, Raoul Belzeaux, Thierry Bougerol, Iréna Cussac, Philippe Courtet, Bruno Etain, Sébastien Gard, Sophie Job, Jean-Pierre Kahn, Marion Leboyer, Emilie Olié, Chantal Henry, Christine Passerieux
BackgroundThe relationship between residual depressive symptoms, cognition and functioning in patients with euthymic bipolar disorder is a subject of debate.AimsTo assess whether cognition mediates the association between residual depressive symptoms and functioning in patients with bipolar disorder who were euthymic.MethodWe included 241 adults with euthymic bipolar disorder in a multicentre cross-sectional study. We used a battery of tests to assess six cognition domains. A path analysis was then used to perform a mediation analysis of the relationship between residual depressive symptoms, cognitive components and functioning...
October 19, 2017: British Journal of Psychiatry: the Journal of Mental Science
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